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Conserved domains on  [gi|291291688|gb|ADD91679|]
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50S ribosomal protein L11 [Enterococcus faecium]

Protein Classification

50S ribosomal protein L11 methyltransferase( domain architecture ID 11455142)

50S ribosomal protein L11 methyltransferase is a class I SAM-dependent methyltransferase that methylates ribosomal protein L11 using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-313 4.52e-119

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 343.69  E-value: 4.52e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   1 MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDvehfqsdqygeildkndftSLKEGALVMAYFPETTFLPEILPF 80
Cdd:COG2264    1 MKWIELTITTPEEAAEALSDALEELGAEGVEIEDAPP-------------------GLWERVGVKAYFPEDEDLEELLAA 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  81 IKDRITQLPEFglaigknKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHP 160
Cdd:COG2264   62 LAEALGELGAP-------EITVEEVEEEDWVEEWKKYFKPIRVGDRLVIVPSWEEY-EPDPGEIVIEIDPGMAFGTGTHP 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 161 TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTgiEI 240
Cdd:COG2264  134 TTRLCLEALEKLLKPGKTVLDVGCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLLE--DG 211

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 291291688 241 ESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPE 313
Cdd:COG2264  212 PYDLVVANILANPLIELAPDLAALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRKKA 284
 
Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-313 4.52e-119

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 343.69  E-value: 4.52e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   1 MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDvehfqsdqygeildkndftSLKEGALVMAYFPETTFLPEILPF 80
Cdd:COG2264    1 MKWIELTITTPEEAAEALSDALEELGAEGVEIEDAPP-------------------GLWERVGVKAYFPEDEDLEELLAA 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  81 IKDRITQLPEFglaigknKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHP 160
Cdd:COG2264   62 LAEALGELGAP-------EITVEEVEEEDWVEEWKKYFKPIRVGDRLVIVPSWEEY-EPDPGEIVIEIDPGMAFGTGTHP 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 161 TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTgiEI 240
Cdd:COG2264  134 TTRLCLEALEKLLKPGKTVLDVGCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLLE--DG 211

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 291291688 241 ESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPE 313
Cdd:COG2264  212 PYDLVVANILANPLIELAPDLAALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRKKA 284
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 2-311 3.53e-115

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 334.23  E-value: 3.53e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688    2 KWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSDQYGEildknDFTSLKEGALVMAYFPETTFLPEILPFI 81
Cdd:pfam06325   1 TWLELSIHTTREAAEPVSNILEEFGALGVAIEDADLLEDRDIFEPGL-----GEERLWDEVRVKALFDEETDALELIAQL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   82 KDRItqlpeFGLAIGKnkVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHPT 161
Cdd:pfam06325  76 AELI-----GGLDSPK--VTVEEVAEEDWARAWKKYFHPVRIGERLTIVPSWEDY-PENPDALNIELDPGMAFGTGTHPT 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  162 TSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSAndLLTGIEIE 241
Cdd:pfam06325 148 TKLCLEALERLVKPGESVLDVGCGSGILAIAALKLGAKKVVGVDIDPVAVRAAKENAELNGVEARLEVYL--PGDLPKEK 225

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  242 SDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAmLEQGFIVDQIFQQKDWYAIILKK 311
Cdd:pfam06325 226 ADVVVANILADPLIELAPDIYALVKPGGYLILSGILKEQAQMVAEA-YSQGFELITVEHREEWVCIVGKK 294
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
1-312 2.02e-110

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 320.56  E-value: 2.02e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   1 MKWNEVKVETESEAVEAVANILMEAGASgvaiedsldvehfqsdqygeildkndftslkegalvmayfpettflpeilpf 80
Cdd:PRK00517   1 MKWIELTLNTTPEAAEALSDILMELGAL---------------------------------------------------- 28

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  81 ikDRITQLPEFGLAIGKNKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDplEKIITLDPGMAFGTGTHP 160
Cdd:PRK00517  29 --AALANLAGLGLDLGEPTYTIEEVEDEDWEREWKKYFHPIRIGDRLWIVPSWEDPPDPD--EINIELDPGMAFGTGTHP 104

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 161 TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLltgiei 240
Cdd:PRK00517 105 TTRLCLEALEKLVLPGKTVLDVGCGSGILAIAAAKLGAKKVLAVDIDPQAVEAARENAELNGVELNVYLPQGDL------ 178

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 291291688 241 ESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKP 312
Cdd:PRK00517 179 KADVIVANILANPLLELAPDLARLLKPGGRLILSGILEEQADEVLEAYEEAGFTLDEVLERGEWVALVGKKK 250
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 3-304 1.01e-86

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 261.69  E-value: 1.01e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688    3 WNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSDQYGEildkndfTSLKEGALVMAYFPETTFLPEILpfik 82
Cdd:TIGR00406   1 WIEIRINTTKELAEATSDALEEAGAVGVTFEDDKDTIYFEPHLPGE-------KRLWGNLDVIALFDAETDMNNSV---- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   83 drITQLPEFGLAIGKNKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHPTT 162
Cdd:TIGR00406  70 --IPLLEAFCLDLGRNHKIEFDEFSKDWERAWKDNFHPVQFGKRFWICPSWRDV-PSDEDALIIMLDPGLAFGTGTHPTT 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  163 SLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTGIEIES 242
Cdd:TIGR00406 147 SLCLEWLEDLDLKDKNVIDVGCGSGILSIAALKLGAAKVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQPIEGKA 226

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 291291688  243 DVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAmLEQGFIVDQIFQQKDW 304
Cdd:TIGR00406 227 DVIVANILAEVIKELYPQFSRLVKPGGWLILSGILETQAQSVCDA-YEQGFTVVEIRQREEW 287
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 178-274 1.31e-08

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 52.05  E-value: 1.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 178 TLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEiAKDVHVSANDLLTGIEIES---DVIVANILADII 254
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALL-ADNVEVLKGDAEELPPEADesfDVIISDPPLHHL 79

                         90       100
                 ....*....|....*....|....
gi 291291688 255 LLMIPD----AWRLLKQTGTLIVS 274
Cdd:cd02440   80 VEDLARfleeARRLLKPGGVLVLT 103
 
Name Accession Description Interval E-value
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
1-313 4.52e-119

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 343.69  E-value: 4.52e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   1 MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDvehfqsdqygeildkndftSLKEGALVMAYFPETTFLPEILPF 80
Cdd:COG2264    1 MKWIELTITTPEEAAEALSDALEELGAEGVEIEDAPP-------------------GLWERVGVKAYFPEDEDLEELLAA 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  81 IKDRITQLPEFglaigknKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHP 160
Cdd:COG2264   62 LAEALGELGAP-------EITVEEVEEEDWVEEWKKYFKPIRVGDRLVIVPSWEEY-EPDPGEIVIEIDPGMAFGTGTHP 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 161 TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTgiEI 240
Cdd:COG2264  134 TTRLCLEALEKLLKPGKTVLDVGCGSGILAIAAAKLGAKRVLAVDIDPVAVEAARENAELNGVEDRIEVVLGDLLE--DG 211

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 291291688 241 ESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPE 313
Cdd:COG2264  212 PYDLVVANILANPLIELAPDLAALLKPGGYLILSGILEEQADEVLAAYEAAGFELVERRERGEWVALVLRKKA 284
PrmA pfam06325
Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal ...
 2-311 3.53e-115

Ribosomal protein L11 methyltransferase (PrmA); This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.


Pssm-ID: 428888 [Multi-domain]  Cd Length: 294  Bit Score: 334.23  E-value: 3.53e-115
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688    2 KWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSDQYGEildknDFTSLKEGALVMAYFPETTFLPEILPFI 81
Cdd:pfam06325   1 TWLELSIHTTREAAEPVSNILEEFGALGVAIEDADLLEDRDIFEPGL-----GEERLWDEVRVKALFDEETDALELIAQL 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   82 KDRItqlpeFGLAIGKnkVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHPT 161
Cdd:pfam06325  76 AELI-----GGLDSPK--VTVEEVAEEDWARAWKKYFHPVRIGERLTIVPSWEDY-PENPDALNIELDPGMAFGTGTHPT 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  162 TSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSAndLLTGIEIE 241
Cdd:pfam06325 148 TKLCLEALERLVKPGESVLDVGCGSGILAIAALKLGAKKVVGVDIDPVAVRAAKENAELNGVEARLEVYL--PGDLPKEK 225

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  242 SDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAmLEQGFIVDQIFQQKDWYAIILKK 311
Cdd:pfam06325 226 ADVVVANILADPLIELAPDIYALVKPGGYLILSGILKEQAQMVAEA-YSQGFELITVEHREEWVCIVGKK 294
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
1-312 2.02e-110

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 320.56  E-value: 2.02e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   1 MKWNEVKVETESEAVEAVANILMEAGASgvaiedsldvehfqsdqygeildkndftslkegalvmayfpettflpeilpf 80
Cdd:PRK00517   1 MKWIELTLNTTPEAAEALSDILMELGAL---------------------------------------------------- 28

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  81 ikDRITQLPEFGLAIGKNKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDplEKIITLDPGMAFGTGTHP 160
Cdd:PRK00517  29 --AALANLAGLGLDLGEPTYTIEEVEDEDWEREWKKYFHPIRIGDRLWIVPSWEDPPDPD--EINIELDPGMAFGTGTHP 104

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 161 TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLltgiei 240
Cdd:PRK00517 105 TTRLCLEALEKLVLPGKTVLDVGCGSGILAIAAAKLGAKKVLAVDIDPQAVEAARENAELNGVELNVYLPQGDL------ 178

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 291291688 241 ESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKP 312
Cdd:PRK00517 179 KADVIVANILANPLLELAPDLARLLKPGGRLILSGILEEQADEVLEAYEEAGFTLDEVLERGEWVALVGKKK 250
prmA TIGR00406
ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an ...
 3-304 1.01e-86

ribosomal protein L11 methyltransferase; Ribosomal protein L11 methyltransferase is an S-adenosyl-L-methionine-dependent methyltransferase required for the modification of ribosomal protein L11. This protein is found in bacteria and (with a probable transit peptide) in Arabidopsis. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 273061  Cd Length: 288  Bit Score: 261.69  E-value: 1.01e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688    3 WNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSDQYGEildkndfTSLKEGALVMAYFPETTFLPEILpfik 82
Cdd:TIGR00406   1 WIEIRINTTKELAEATSDALEEAGAVGVTFEDDKDTIYFEPHLPGE-------KRLWGNLDVIALFDAETDMNNSV---- 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688   83 drITQLPEFGLAIGKNKVTVSEVEESNWATAWKKYYHPVRITRMLTVAPSWENYqTEDPLEKIITLDPGMAFGTGTHPTT 162
Cdd:TIGR00406  70 --IPLLEAFCLDLGRNHKIEFDEFSKDWERAWKDNFHPVQFGKRFWICPSWRDV-PSDEDALIIMLDPGLAFGTGTHPTT 146

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  163 SLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTGIEIES 242
Cdd:TIGR00406 147 SLCLEWLEDLDLKDKNVIDVGCGSGILSIAALKLGAAKVVGIDIDPLAVESARKNAELNQVSDRLQVKLIYLEQPIEGKA 226

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 291291688  243 DVIVANILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAmLEQGFIVDQIFQQKDW 304
Cdd:TIGR00406 227 DVIVANILAEVIKELYPQFSRLVKPGGWLILSGILETQAQSVCDA-YEQGFTVVEIRQREEW 287
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 148-273 1.85e-16

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 76.00  E-value: 1.85e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 148 LDPGmafgtgthptTSLTLTALETVLRGgeTLLDVGTGSGVLSIA-AKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAkD 226
Cdd:COG2813   34 LDIG----------TRLLLEHLPEPLGG--RVLDLGCGYGVIGLAlAKRNPEARVTLVDVNARAVELARANAAANGLE-N 100

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 291291688 227 VHVSANDLLTGIEIES-DVIVAN--------ILADIILLMIPDAWRLLKQTGTLIV 273
Cdd:COG2813  101 VEVLWSDGLSGVPDGSfDLILSNppfhagraVDKEVAHALIADAARHLRPGGELWL 156
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 145-273 3.86e-12

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 63.38  E-value: 3.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  145 IITLDPGMAFGTGTHPTTSLTLTALETVLRGgeTLLDVGTGSGVLSIAAKYLGAK-DVYAFDLDEVAVRSAKENMDMNEI 223
Cdd:pfam05175   3 TFKTLPGVFSHGRLDIGSRLLLEHLPKDLSG--KVLDLGCGAGVLGAALAKESPDaELTMVDINARALESARENLAANGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 291291688  224 aKDVHVSANDLLTGIEIES-DVIVAN--------ILADIILLMIPDAWRLLKQTGTLIV 273
Cdd:pfam05175  81 -ENGEVVASDVYSGVEDGKfDLIISNppfhaglaTTYNVAQRFIADAKRHLRPGGELWI 138
HemK COG2890
Methylase of polypeptide chain release factors [Translation, ribosomal structure and ...
 167-273 1.34e-11

Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis];


Pssm-ID: 442135 [Multi-domain]  Cd Length: 282  Bit Score: 64.02  E-value: 1.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 167 TALETVLRGGE-TLLDVGTGSGVLSIA-AKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTGIEIES-- 242
Cdd:COG2890  103 LALALLPAGAPpRVLDLGTGSGAIALAlAKERPDARVTAVDISPDALAVARRNAERLGLEDRVRFLQGDLFEPLPGDGrf 182

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 243 DVIVAN---------------------ILA--------DIILLMIPDAWRLLKQTGTLIV 273
Cdd:COG2890  183 DLIVSNppyipedeiallppevrdhepRLAldggedglDFYRRIIAQAPRLLKPGGWLLL 242
PRK09328 PRK09328
N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional
 167-311 4.68e-11

N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional


Pssm-ID: 236467 [Multi-domain]  Cd Length: 275  Bit Score: 62.10  E-value: 4.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 167 TALETVLRGGE-TLLDVGTGSGVLSIA-AKYLGAKDVYAFDLDEVAVRSAKENMDMNEiAKDVHVSANDLLTGIEIES-D 243
Cdd:PRK09328  99 WALEALLLKEPlRVLDLGTGSGAIALAlAKERPDAEVTAVDISPEALAVARRNAKHGL-GARVEFLQGDWFEPLPGGRfD 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 244 VIVAN---------------------ILA--------DIILLMIPDAWRLLKQTGTLIvsgiieekkqmvldamLE---- 290
Cdd:PRK09328 178 LIVSNppyipeadihllqpevrdhepHLAlfggedglDFYRRIIEQAPRYLKPGGWLL----------------LEigyd 241

                        170       180
                 ....*....|....*....|.
gi 291291688 291 QGFIVDQIFQQKDWYAIILKK 311
Cdd:PRK09328 242 QGEAVRALLAAAGFADVETRK 262
PRK14967 PRK14967
putative methyltransferase; Provisional
 176-248 3.94e-10

putative methyltransferase; Provisional


Pssm-ID: 184931 [Multi-domain]  Cd Length: 223  Bit Score: 58.91  E-value: 3.94e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 291291688 176 GETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNeiAKDVHVSANDLLTGIEIES-DVIVAN 248
Cdd:PRK14967  37 GRRVLDLCTGSGALAVAAAAAGAGSVTAVDISRRAVRSARLNALLA--GVDVDVRRGDWARAVEFRPfDVVVSN 108
PRK14968 PRK14968
putative methyltransferase; Provisional
 172-248 5.60e-10

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 57.60  E-value: 5.60e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 291291688 172 VLRGGETLLDVGTGSGVLSIAAKYLGaKDVYAFDLDEVAVRSAKENMDMNEI-AKDVHVSANDLLTGIEIES-DVIVAN 248
Cdd:PRK14968  20 VDKKGDRVLEVGTGSGIVAIVAAKNG-KKVVGVDINPYAVECAKCNAKLNNIrNNGVEVIRSDLFEPFRGDKfDVILFN 97
COG2263 COG2263
Predicted RNA methylase [General function prediction only];
176-248 5.64e-10

Predicted RNA methylase [General function prediction only];


Pssm-ID: 441864 [Multi-domain]  Cd Length: 199  Bit Score: 57.99  E-value: 5.64e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 291291688 176 GETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKEN-MDMNEIAKDVHVSANDLltGIEIESDVIVAN 248
Cdd:COG2263   46 GKTVLDLGCGTGMLAIGAALLGAKKVVGVDIDPEALEIARENaERLGVRVDFIRADVTRI--PLGGSVDTVVMN 117
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
168-272 1.39e-09

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 57.35  E-value: 1.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 168 ALETVLRGGETLLDVGTGSGVLS-IAAKYlGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVsANDLLTGIEIE--SDV 244
Cdd:COG4076   28 AIERVVKPGDVVLDIGTGSGLLSmLAARA-GAKKVYAVEVNPDIAAVARRIIAANGLSDRITV-INADATDLDLPekADV 105

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 291291688 245 IVANILaDIILL---MIP---DAW-RLLKQTGTLI 272
Cdd:COG4076  106 IISEML-DTALLdegQVPilnHARkRLLKPGGRII 139
TrmN6 COG4123
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ...
 173-248 1.74e-09

tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443299 [Multi-domain]  Cd Length: 238  Bit Score: 57.08  E-value: 1.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 173 LRGGETLLDVGTGSGVLSI--AAKYLGAKdVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLT---GIEIES-DVIV 246
Cdd:COG4123   35 VKKGGRVLDLGTGTGVIALmlAQRSPGAR-ITGVEIQPEAAELARRNVALNGLEDRITVIHGDLKEfaaELPPGSfDLVV 113


                 ..
gi 291291688 247 AN 248
Cdd:COG4123  114 SN 115
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 178-274 1.31e-08

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 52.05  E-value: 1.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 178 TLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEiAKDVHVSANDLLTGIEIES---DVIVANILADII 254
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALL-ADNVEVLKGDAEELPPEADesfDVIISDPPLHHL 79

                         90       100
                 ....*....|....*....|....
gi 291291688 255 LLMIPD----AWRLLKQTGTLIVS 274
Cdd:cd02440   80 VEDLARfleeARRLLKPGGVLVLT 103
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 169-274 2.41e-08

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 51.56  E-value: 2.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 169 LETVLRGGETLLDVGTGSGVLSIAAKYLGAkDVYAFDLDEVAVRSAKENMDmneiAKDVHVSANDLLTgIEIES---DVI 245
Cdd:COG2227   18 LARLLPAGGRVLDVGCGTGRLALALARRGA-DVTGVDISPEALEIARERAA----ELNVDFVQGDLED-LPLEDgsfDLV 91

                         90       100       110
                 ....*....|....*....|....*....|..
gi 291291688 246 VA-NILADI--ILLMIPDAWRLLKQTGTLIVS 274
Cdd:COG2227   92 ICsEVLEHLpdPAALLRELARLLKPGGLLLLS 123
Trm5 COG2520
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ...
 174-296 9.89e-08

tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442010 [Multi-domain]  Cd Length: 333  Bit Score: 52.56  E-value: 9.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 174 RGGETLLDVGTGSGVLSI-AAKYLGAKdVYAFDLDEVAVRSAKENMDMNEIAKDVHVS---ANDLLTGIEIESDVIVANi 249
Cdd:COG2520  179 KPGERVLDMFAGVGPFSIpIAKRSGAK-VVAIDINPDAVEYLKENIRLNKVEDRVTPIlgdAREVAPELEGKADRIIMN- 256

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 291291688 250 LADIILLMIPDAWRLLKQTGTLIV------SGIIEEKKQMVLDAMLEQGFIVD 296
Cdd:COG2520  257 LPHSADEFLDAALRALKPGGVIHYyeivpeEDPFERAEERIEEAAEEAGYEVE 309
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 173-293 2.37e-07

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 49.22  E-value: 2.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 173 LRGGETLLDVGTGSGVLSIAAKYLGAKdVYAFDLDEVAVRSAKENM-DMNEIAKDVHVSANDLltGIEIES-DVIVANIL 250
Cdd:COG2226   20 LRPGARVLDLGCGTGRLALALAERGAR-VTGVDISPEMLELARERAaEAGLNVEFVVGDAEDL--PFPDGSfDLVISSFV 96

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 291291688 251 adiiLLMIPD-------AWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGF 293
Cdd:COG2226   97 ----LHHLPDperalaeIARVLKPGGRLVVVDFSPPDLAELEELLAEAGF 142
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 173-293 6.09e-07

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 49.03  E-value: 6.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 173 LRGGETLLDVGTGSGVLSI-AAKYLGAKD-VYAFDLDEVAVRSAKENMDMNEIAKDVHV---SANDLLTGIEIESDVIVA 247
Cdd:PRK00377  38 LRKGDMILDIGCGTGSVTVeASLLVGETGkVYAVDKDEKAINLTRRNAEKFGVLNNIVLikgEAPEILFTINEKFDRIFI 117

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 291291688 248 NILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGF 293
Cdd:PRK00377 118 GGGSEKLKEIISASWEIIKKGGRIVIDAILLETVNNALSALENIGF 163
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 173-308 9.52e-07

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 47.80  E-value: 9.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  173 LRGGETLLDVGTGSGVLSI-AAKYLGAK-DVYAFDLDEVAVRSAKENMDMNEIA--KDVHVSANDLLTGIEIES-DVIVA 247
Cdd:pfam13847   1 IDKGMRVLDLGCGTGHLSFeLAEELGPNaEVVGIDISEEAIEKARENAQKLGFDnvEFEQGDIEELPELLEDDKfDVVIS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  248 N-------ILADIILLMIpdawRLLKQTGTLIVS--GIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAII 308
Cdd:pfam13847  81 NcvlnhipDPDKVLQEIL----RVLKPGGRLIISdpDSLAELPAHVKEDSTYYAGCVGGAILKKKLYELL 146
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 173-310 1.06e-06

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 48.37  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 173 LRGGETLLDVGTGSGVLSIA-AKYLGAKdVYAFDLDEVAVRSAKENMDMNEIAKdVHVSANDLLTGIEIES---DVIVAN 248
Cdd:COG0500   24 LPKGGRVLDLGCGTGRNLLAlAARFGGR-VIGIDLSPEAIALARARAAKAGLGN-VEFLVADLAELDPLPAesfDLVVAF 101

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 291291688 249 -----ILADIILLMIPDAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILK 310
Cdd:COG0500  102 gvlhhLPPEEREALLRELARALKPGGVLLLSASDAAAALSLARLLLLATASLLELLLLLRLLALELY 168
TRM1 COG1867
tRNA G26 N,N-dimethylase Trm1 [Translation, ribosomal structure and biogenesis]; tRNA G26 N, ...
 162-235 1.13e-06

tRNA G26 N,N-dimethylase Trm1 [Translation, ribosomal structure and biogenesis]; tRNA G26 N,N-dimethylase Trm1 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441472  Cd Length: 383  Bit Score: 49.49  E-value: 1.13e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 291291688 162 TSLTLTALETVLRGGETLLDVGTGSGVLSI-AAKYLGAKdVYAFDLDEVAVRSAKENMDMNEIaKDVHVS---ANDLL 235
Cdd:COG1867   44 SVAALRAYRERLKREISYLDALAASGIRGLrYALEVGIK-VTLNDIDPEAVELIRENLELNGL-EDVEVYnrdANALL 119
Trm11 COG1041
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ...
 171-302 1.98e-06

tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 440663 [Multi-domain]  Cd Length: 172  Bit Score: 47.25  E-value: 1.98e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 171 TVLRGGETLLD--VGTGsGVLsIAAKYLGAkDVYAFDLDEVAVRSAKENMDMNEIAK-DVHVS-ANDLltGIEIES-DVI 245
Cdd:COG1041   22 AGAKEGDTVLDpfCGTG-TIL-IEAGLLGR-RVIGSDIDPKMVEGARENLEHYGYEDaDVIRGdARDL--PLADESvDAI 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 291291688 246 V------------ANILADIILLMIPDAWRLLKQTGTLIVSGIIEekkqmVLDAMLEQGFIVDQIFQQK 302
Cdd:COG1041   97 VtdppygrsskisGEELLELYEKALEEAARVLKPGGRVVIVTPRD-----IDELLEEAGFKVLERHEQR 160
CobL COG2242
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ...
 164-293 2.70e-06

Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 441843 [Multi-domain]  Cd Length: 403  Bit Score: 48.62  E-value: 2.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 164 LTLTALEtvLRGGETLLDVGTGSGVLSI-AAKYLGAKDVYAFDLDEVAVRSAKENMD-MNeiAKDVHV---SANDLLTGI 238
Cdd:COG2242  238 LTLAKLA--LRPGDVLWDIGAGSGSVSIeAARLAPGGRVYAIERDPERAALIRANARrFG--VPNVEVvegEAPEALADL 313

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 291291688 239 EiESDVIVanI------LADIILLmipdAWRLLKQTGTLIVSGIIEEKKQMVLDAMLEQGF 293
Cdd:COG2242  314 P-DPDAVF--IggsggnLPEILEA----CWARLRPGGRLVANAVTLETLALALEALAELGY 367
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 148-247 3.65e-06

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 46.08  E-value: 3.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 148 LDPGMAFGTGTHPTTSLTLTALET----------VLRGGETLLDVGTGSGVLSI-AAKYLGAKdVYAFDLDEVAVRSAKE 216
Cdd:COG2230   14 LDPTMTYSCAYFEDPDDTLEEAQEakldlilrklGLKPGMRVLDIGCGWGGLALyLARRYGVR-VTGVTLSPEQLEYARE 92

                         90       100       110
                 ....*....|....*....|....*....|..
gi 291291688 217 NMDMNEIAKDVHVSANDLLTGIEIES-DVIVA 247
Cdd:COG2230   93 RAAEAGLADRVEVRLADYRDLPADGQfDAIVS 124
CbiT TIGR02469
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes ...
 164-276 6.20e-06

precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes the CbiT methylase which is responsible, in part (along with CbiE), for methylating precorrin-6y (or cobalt-precorrin-6y) at both the 5 and 15 positions as well as the concomitant decarbozylation at C-12. In many organisms, this protein is fused to the CbiE subunit. The fused protein, when found in organisms catalyzing the oxidative version of the cobalamin biosynthesis pathway, is called CobL. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 274148 [Multi-domain]  Cd Length: 124  Bit Score: 44.63  E-value: 6.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  164 LTLTALEtvLRGGETLLDVGTGSGVLSI-AAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHV--SANDLLTGIEI 240
Cdd:TIGR02469  10 LTLAKLR--LRPGDVLWDIGAGTGSVTIeAARLVPNGRVYAIERNPEALDLIERNLRRFGVSNIVIVegDAPEAPEALLP 87

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 291291688  241 ESDVIV----ANILADIILLmipdAWRLLKQTGTLIVSGI 276
Cdd:TIGR02469  88 DPDAVFvggsGGLLQEILEA----VERRLRPGGRIVLNAI 123
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
175-274 8.37e-06

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 43.66  E-value: 8.37e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 175 GGETLLDVGTGSGVLS--IAAKYLGAkDVYAFDLDEVAVRSAKENMDmneiakDVHVSANDLLTgIEIES--DVIVAN-- 248
Cdd:COG4106    1 PPRRVLDLGCGTGRLTalLAERFPGA-RVTGVDLSPEMLARARARLP------NVRFVVADLRD-LDPPEpfDLVVSNaa 72

                         90       100
                 ....*....|....*....|....*...
gi 291291688 249 --ILADIILLmIPDAWRLLKQTGTLIVS 274
Cdd:COG4106   73 lhWLPDHAAL-LARLAAALAPGGVLAVQ 99
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 180-267 8.68e-06

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 43.71  E-value: 8.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  180 LDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHV-SANDLltGIEIES-DVIVANILadIILLM 257
Cdd:pfam13649   2 LDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAEAGLNVEFVQgDAEDL--PFPDGSfDLVVSSGV--LHHLP 77

                          90
                  ....*....|
gi 291291688  258 IPDAWRLLKQ 267
Cdd:pfam13649  78 DPDLEAALRE 87
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 173-299 7.74e-05

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 43.22  E-value: 7.74e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 173 LRGGETLLDVGTGSGVLSIA-AKYLGAK-DVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTGIEiESDVivanil 250
Cdd:COG2519   89 IFPGARVLEAGTGSGALTLAlARAVGPEgKVYSYERREDFAEIARKNLERFGLPDNVELKLGDIREGID-EGDV------ 161

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 291291688 251 aDIILLMIPDAWRLLKQTGT-LIVSGIIE------EKKQMVLDAMLEQGFIVDQIF 299
Cdd:COG2519  162 -DAVFLDMPDPWEALEAVAKaLKPGGVLVayvptvNQVSKLVEALRESGFTDIEAV 216
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 166-273 2.36e-04

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 41.23  E-value: 2.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 166 LTALEtvLRGGETLLDVGTGSG----VLSiaakYLGAKdVYAFDLDEVAVRSAKENMDMNEIAkDVHVSANDLLTGIEIE 241
Cdd:COG2518   59 LEALD--LKPGDRVLEIGTGSGyqaaVLA----RLAGR-VYSVERDPELAERARERLAALGYD-NVTVRVGDGALGWPEH 130

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 291291688 242 S--DVIVANILADIillmIPDAW-RLLKQTGTLIV 273
Cdd:COG2518  131 ApfDRIIVTAAAPE----VPEALlEQLAPGGRLVA 161
hemK_fam TIGR00536
HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme ...
 180-248 2.40e-04

HemK family putative methylases; The gene hemK from E. coli was found to contribute to heme biosynthesis and originally suggested to be protoporphyrinogen oxidase. Functional analysis of the nearest homolog in Saccharomyces cerevisiae, YNL063w, finds it is not protoporphyrinogen oxidase and sequence analysis suggests that HemK homologs have S-adenosyl-methionine-dependent methyltransferase activity (Medline 99237242). Homologs are found, usually in a single copy, in nearly all completed genomes, but varying somewhat in apparent domain architecture. Both E. coli and H. influenzae have two members rather than one. The members from the Mycoplasmas have an additional C-terminal domain. [Protein fate, Protein modification and repair]


Pssm-ID: 273125 [Multi-domain]  Cd Length: 284  Bit Score: 41.96  E-value: 2.40e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 291291688  180 LDVGTGSGVLSIA-AKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDLLTGIE-IESDVIVAN 248
Cdd:TIGR00536 119 LDLGTGSGCIALAlAYEFPNAEVIAVDISPDALAVAEENAEKNQLEHRVEFIQSNLFEPLAgQKIDIIVSN 189
rsmC PRK09489
16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC;
133-248 2.62e-04

16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC;


Pssm-ID: 181902 [Multi-domain]  Cd Length: 342  Bit Score: 42.23  E-value: 2.62e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 133 WENYQTEDPleKIITLdPGMAFGTGTHPTTSLTLTALETVLRGgeTLLDVGTGSGVLS--IAAKYLGAK----DVYAfdl 206
Cdd:PRK09489 159 WKEYQVDGL--TVKTL-PGVFSRDGLDVGSQLLLSTLTPHTKG--KVLDVGCGAGVLSavLARHSPKIRltlsDVSA--- 230

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 291291688 207 deVAVRSAKENMDMNEIAKDVHVSanDLLTGIEIESDVIVAN 248
Cdd:PRK09489 231 --AALESSRATLAANGLEGEVFAS--NVFSDIKGRFDMIISN 268
PRK04338 PRK04338
N(2),N(2)-dimethylguanosine tRNA methyltransferase; Provisional
 164-245 3.03e-04

N(2),N(2)-dimethylguanosine tRNA methyltransferase; Provisional


Pssm-ID: 235286  Cd Length: 382  Bit Score: 42.21  E-value: 3.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688 164 LTLTALETVLR--GGETLLDVGTGSGVLSI-AAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKD--VHVSANDLLTGi 238
Cdd:PRK04338  44 ISVLVLRAFGPklPRESVLDALSASGIRGIrYALETGVEKVTLNDINPDAVELIKKNLELNGLENEkvFNKDANALLHE- 122


                 ....*..
gi 291291688 239 EIESDVI 245
Cdd:PRK04338 123 ERKFDVV 129
UPF0020 pfam01170
Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated ...
 174-248 5.05e-04

Putative RNA methylase family UPF0020; This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.


Pssm-ID: 395932 [Multi-domain]  Cd Length: 184  Bit Score: 40.42  E-value: 5.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  174 RGGETLLDVGTGSGVLSIAAKYLGAK------------DVYAFDLDEVAVRSAKENMDMNEIAKDVHVSANDL--LTGIE 239
Cdd:pfam01170  27 KPGDPLLDPMCGSGTILIEAALMGANiapgkfdarvraPLYGSDIDRRMVQGARLNAENAGVGDLIEFVQADAadLPLLE 106


                  ....*....
gi 291291688  240 IESDVIVAN 248
Cdd:pfam01170 107 GSVDVIVTN 115
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 180-271 6.35e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 38.50  E-value: 6.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  180 LDVGTGSGVLSIA-AKYLGAKDVYAFDLDEVAVRSAKENMDMNEI--AKDVHVSANDLLTGIEIESDVIVANI----LAD 252
Cdd:pfam08242   1 LEIGCGTGTLLRAlLEALPGLEYTGLDISPAALEAARERLAALGLlnAVRVELFQLDLGELDPGSFDVVVASNvlhhLAD 80

                          90
                  ....*....|....*....
gi 291291688  253 IILLMIpDAWRLLKQTGTL 271
Cdd:pfam08242  81 PRAVLR-NIRRLLKPGGVL 98
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 180-273 7.85e-04

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 38.03  E-value: 7.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  180 LDVGTGSGVLSIAAKYLGAkDVYAFDLDEVAVRSAKENMDmNEIAKDVHVSANDLltGIEIES-DVIVANILadiiLLMI 258
Cdd:pfam08241   1 LDVGCGTGLLTELLARLGA-RVTGVDISPEMLELAREKAP-REGLTFVVGDAEDL--PFPDNSfDLVLSSEV----LHHV 72

                          90       100
                  ....*....|....*....|..
gi 291291688  259 PD-------AWRLLKQTGTLIV 273
Cdd:pfam08241  73 EDperalreIARVLKPGGILII 94
Cons_hypoth95 pfam03602
Conserved hypothetical protein 95;
155-279 8.88e-04

Conserved hypothetical protein 95;


Pssm-ID: 427391 [Multi-domain]  Cd Length: 179  Bit Score: 39.53  E-value: 8.88e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 291291688  155 GTGTHPTTSLTLTALETVLR---GGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDVHV-- 229
Cdd:pfam03602  18 GPGTRPTTDRVREALFNWLApyiEGARVLDLFAGSGALGLEALSRGAKRVTLVEKDKRAVQILKENLQLLGLPGAVLVmd 97

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 291291688  230 SANDLLTgieiesdVIVANILADIILLMIPDAWRLLKQTGTLIV-SGIIEE 279
Cdd:pfam03602  98 ALLALLR-------LAGKGPVFDIVFLDPPYAKGLIEEVLDLLAeKGWLKP 141
TIGR00095 TIGR00095
16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of ...
 155-217 1.24e-03

16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; This model represents a family of uncharacterized bacterial proteins. Members are present in nearly every complete bacterial genome, always in a single copy. PSI-BLAST analysis shows homology to several families of SAM-dependent methyltransferases, including ribosomal RNA adenine dimethylases. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 188022 [Multi-domain]  Cd Length: 190  Bit Score: 39.31  E-value: 1.24e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 291291688  155 GTGTHPTTSLTLTALETVLRG---GETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKEN 217
Cdd:TIGR00095  27 GPSTRPTTDRVRESLFNILRPdivGAHFLDLFAGSGALGLEALSRGAASAVFVEQDRKVAQTLKEN 92
Met_10 pfam02475
Met-10+ like-protein; The methionine-10 mutant allele of N. crassa codes for a protein of ...
 176-227 3.42e-03

Met-10+ like-protein; The methionine-10 mutant allele of N. crassa codes for a protein of unknown function, Swiss:O27901. However, homologous proteins have been found in yeast suggesting this protein may be involved in methionine biosynthesis, transport and/or utilization.


Pssm-ID: 396850 [Multi-domain]  Cd Length: 198  Bit Score: 38.10  E-value: 3.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 291291688  176 GETLLDVGTGSGVLSI-AAKYLGAKDVYAFDLDEVAVRSAKENMDMNEIAKDV 227
Cdd:pfam02475 100 GEVVVDMFAGIGPFSIpIAKHSKARRVYAIELNPESYKYLKENIKLNKVEDVV 152
Methyltransf_23 pfam13489
Methyltransferase domain; This family appears to be a methyltransferase domain.
 166-220 6.51e-03

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 404385 [Multi-domain]  Cd Length: 162  Bit Score: 36.64  E-value: 6.51e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 291291688  166 LTALETVLRGGETLLDVGTGSGVLSIAAKYLGAkDVYAFDLDEVAVRSAKENMDM 220
Cdd:pfam13489  13 LLRLLPKLPSPGRVLDFGCGTGIFLRLLRAQGF-SVTGVDPSPIAIERALLNVRF 66
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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