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Conserved domains on  [gi|308912655|gb|ADO51418|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Oscarella microlobata]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009544)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00057
NADH dehydrogenase subunit 6; Provisional
 1-197 1.18e-89

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177129 [Multi-domain]  Cd Length: 186  Bit Score: 260.70  E-value: 1.18e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   1 MEGLFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLE 80
Cdd:MTH00057   1 MEGLFYLFALGVIISGIMVISALNPVHSVLWLIVAFTSASALFILLEVEFIALIFLIVYVGAIAILFLFVIMMLNLTDLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  81 GGGDMSNYIPIGSVIGVLLLFEVlimgreataysYRDIDHECLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIA 160
Cdd:MTH00057  81 GGGDMSNYLPAGFIIGVVFLFEV-----------SSGISLLSSGTKIGQWDFPNWIEKESNIEVLGRVLYTDYYYLFILA 149

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 308912655 161 SFILLVAMIGAIVLTHELGAELKRQDLFIQTSRSLWQ 197
Cdd:MTH00057 150 SFILLVAMIGAIVLTHDLIIEIKRQDIFIQTSRQLWQ 186
 
Name Accession Description Interval E-value
ND6 MTH00057
NADH dehydrogenase subunit 6; Provisional
 1-197 1.18e-89

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177129 [Multi-domain]  Cd Length: 186  Bit Score: 260.70  E-value: 1.18e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   1 MEGLFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLE 80
Cdd:MTH00057   1 MEGLFYLFALGVIISGIMVISALNPVHSVLWLIVAFTSASALFILLEVEFIALIFLIVYVGAIAILFLFVIMMLNLTDLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  81 GGGDMSNYIPIGSVIGVLLLFEVlimgreataysYRDIDHECLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIA 160
Cdd:MTH00057  81 GGGDMSNYLPAGFIIGVVFLFEV-----------SSGISLLSSGTKIGQWDFPNWIEKESNIEVLGRVLYTDYYYLFILA 149

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 308912655 161 SFILLVAMIGAIVLTHELGAELKRQDLFIQTSRSLWQ 197
Cdd:MTH00057 150 SFILLVAMIGAIVLTHDLIIEIKRQDIFIQTSRQLWQ 186
NuoJ COG0839
NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; NADH: ...
 4-177 3.26e-40

NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 6 (chain J) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440601 [Multi-domain]  Cd Length: 162  Bit Score: 134.09  E-value: 3.26e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   4 LFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLEGGG 83
Cdd:COG0839    4 LFYIFAALAVASALGVVTSRNPVHAALYLVLTFLSVAGLYLLLGAEFLAAVQVIVYVGAVMVLFLFVVMLLDLDKEELRE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  84 DMSNYIPIGSVIGVLLLFEVLIMgreataysyrdidhecLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIASFI 163
Cdd:COG0839   84 GFRKYRPLAALVGLLLLAELAYV----------------LLSTSWAAAPAAAAAAVGNTKALGELLFTDYLLPFELASVL 147

                        170
                 ....*....|....
gi 308912655 164 LLVAMIGAIVLTHE 177
Cdd:COG0839  148 LLVAMIGAIVLARR 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-174 2.38e-28

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 103.35  E-value: 2.38e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   17 IMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLEGGgdMSNYIPIGSVIG 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEK--LRSGLPLAALLL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 308912655   97 VLLLFEVLIMGreataysyrdidhecLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIASFILLVAMIGAIVL 174
Cdd:pfam00499  79 GLLLLALLLLV---------------LLSASLTPAAAAAAPDVGNIEAIGELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00057
NADH dehydrogenase subunit 6; Provisional
 1-197 1.18e-89

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177129 [Multi-domain]  Cd Length: 186  Bit Score: 260.70  E-value: 1.18e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   1 MEGLFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLE 80
Cdd:MTH00057   1 MEGLFYLFALGVIISGIMVISALNPVHSVLWLIVAFTSASALFILLEVEFIALIFLIVYVGAIAILFLFVIMMLNLTDLE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  81 GGGDMSNYIPIGSVIGVLLLFEVlimgreataysYRDIDHECLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIA 160
Cdd:MTH00057  81 GGGDMSNYLPAGFIIGVVFLFEV-----------SSGISLLSSGTKIGQWDFPNWIEKESNIEVLGRVLYTDYYYLFILA 149

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 308912655 161 SFILLVAMIGAIVLTHELGAELKRQDLFIQTSRSLWQ 197
Cdd:MTH00057 150 SFILLVAMIGAIVLTHDLIIEIKRQDIFIQTSRQLWQ 186
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-193 4.24e-54

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 170.68  E-value: 4.24e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   7 MFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTD----LEGG 82
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIMLLNLTDfppaFGGE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  83 GDMSNYIPIGSVIGVLLLFEVLIMGREATAYSYRDIDHEClkggvdawdtSIEIIKSSNIEVLGRVLYTDYYYLFIIASF 162
Cdd:MTH00021  81 ADMTNYIPIGLIIGTLFFSEIASSWLIIGGPYVERWDLAF----------PWFLISYHNIEALGRILYITCYYLFLLASF 150

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 308912655 163 ILLVAMIGAIVLTHELGAEL----KRQDLFIQTSR 193
Cdd:MTH00021 151 ILLVAMIGAIVLTQEPGSEVgplsKKQDIFFQISR 185
PRK06638 PRK06638
NADH-quinone oxidoreductase subunit J;
1-193 7.90e-42

NADH-quinone oxidoreductase subunit J;


Pssm-ID: 235844 [Multi-domain]  Cd Length: 198  Bit Score: 139.59  E-value: 7.90e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   1 MEGLFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLtDLE 80
Cdd:PRK06638   4 EAIAFYILALLAVLAALGVVTSRNPVHSALFLILTFLSIAGLYFLLGAEFLGVVQIIVYVGAVMVLFLFVVMMLDV-DFS 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  81 GGGDMSNYIPIGSVIGVLLLFEVLIMgreATAYSYRDIDHECLKGGVDAWdtsieiiksSNIEVLGRVLYTDYYYLFIIA 160
Cdd:PRK06638  83 EREQLREWLPGGVLIGLVILLGLLLL---LIVGAIIAASGVNAQGIAAGE---------GNTKAIGILLFTDYLLPFELA 150

                        170       180       190
                 ....*....|....*....|....*....|...
gi 308912655 161 SFILLVAMIGAIVLTHELGAELKRQDLFIQTSR 193
Cdd:PRK06638 151 SVLLLVAMVGAIVLARRERARVKRQDVPAQLPD 183
NuoJ COG0839
NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; NADH: ...
 4-177 3.26e-40

NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 6 (chain J) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440601 [Multi-domain]  Cd Length: 162  Bit Score: 134.09  E-value: 3.26e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   4 LFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLEGGG 83
Cdd:COG0839    4 LFYIFAALAVASALGVVTSRNPVHAALYLVLTFLSVAGLYLLLGAEFLAAVQVIVYVGAVMVLFLFVVMLLDLDKEELRE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  84 DMSNYIPIGSVIGVLLLFEVLIMgreataysyrdidhecLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIASFI 163
Cdd:COG0839   84 GFRKYRPLAALVGLLLLAELAYV----------------LLSTSWAAAPAAAAAAVGNTKALGELLFTDYLLPFELASVL 147

                        170
                 ....*....|....
gi 308912655 164 LLVAMIGAIVLTHE 177
Cdd:COG0839  148 LLVAMIGAIVLARR 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-174 2.38e-28

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 103.35  E-value: 2.38e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   17 IMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNLTDLEGGgdMSNYIPIGSVIG 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEK--LRSGLPLAALLL 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 308912655   97 VLLLFEVLIMGreataysyrdidhecLKGGVDAWDTSIEIIKSSNIEVLGRVLYTDYYYLFIIASFILLVAMIGAIVL 174
Cdd:pfam00499  79 GLLLLALLLLV---------------LLSASLTPAAAAAAPDVGNIEAIGELLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00213
NADH dehydrogenase subunit 6; Provisional
 21-174 8.25e-28

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177256 [Multi-domain]  Cd Length: 239  Bit Score: 104.60  E-value: 8.25e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  21 SALNPIH------SVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMM-----------------LNLT 77
Cdd:MTH00213  13 SAVTPTYshnflaSVFWLILTFIGSSGLFIVLGMEFLGLIFLIVYVGAICIIFLFVIMMipggakgfkptkgnkkeKERK 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  78 DLEGGGDMSNYIPIGSVIGVLLLFEV-------------------------LIMGREATAYSYRDIDHECLKGGVDAWDT 132
Cdd:MTH00213  93 KGEETGRIGAPPAIGILIGAILAAELasavpdsflnnpsgrggaeryeltnILSDRNRGVSSLLGSDKESITTGIQNNIY 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 308912655 133 SIEIIKS-----------------SNIEVLGRVLYTDYYYLFIIASFILLVAMIGAIVL 174
Cdd:MTH00213 173 MRVGATGapylyndsfftlngsggTNLEAIGSVLYINYYYAFILVSFILLVAMIGAIVL 231
ndhG CHL00016
NADH dehydrogenase subunit 6
 4-174 1.79e-11

NADH dehydrogenase subunit 6


Pssm-ID: 214335 [Multi-domain]  Cd Length: 182  Bit Score: 59.92  E-value: 1.79e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   4 LFYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNltdlegGG 83
Cdd:CHL00016  11 LLVFLGSGLILGSLGVVLLTNPIYSAFSLGLVLVCISLFYILLNADFVAAAQLLIYVGAINVLIIFAVMFMN------GP 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  84 DMSNYIP-------IGSVIGVLLLFEVLIMGREATAYSYRDIDHEclkggvdawDTSIEIIKSSNIEVLGRVLYTDYYYL 156
Cdd:CHL00016  85 EYSKDFNlwtvgdgITSLVCTSLFFSLITTILDTSWYGIIWTTRS---------NQIIEQDLISNVQQIGIHLSTDFLLP 155

                        170
                 ....*....|....*...
gi 308912655 157 FIIASFILLVAMIGAIVL 174
Cdd:CHL00016 156 FELISIILLVALIGAITV 173
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 5-177 1.72e-04

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 40.27  E-value: 1.72e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655   5 FYMFALGVIISGIMVISALNPIHSVFWLIVVFLGASALFILLGIDFIALIFLIVYVG*IAILFLFVIMMLNltdlEGGGD 84
Cdd:MTH00045   3 FYLFLILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSA----ERYPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 308912655  85 MSNyipIGSVIGVLLLFEVLImgreataYSYRDIDHEClkggvdaWDTSIEIIKSSNIEVLGrVLYTDYYYLFIIASFIL 164
Cdd:MTH00045  79 VSN---LGEVLVLSLLLSLWV-------FISFDNFLEL-------SNNNWSLVSLSDLVGSS-ELYNSGGLYLLLGGFIL 140

                        170
                 ....*....|...
gi 308912655 165 LVAMIGAIVLTHE 177
Cdd:MTH00045 141 LVALVVALVISFG 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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