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Conserved domains on  [gi|440462244|gb|AGC08106|]
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LRR-7037, partial [Anopheles gambiae]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
11-191 3.78e-13

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.88  E-value: 3.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  11 AFDGLGHLRLLYMDENQLEKLPEGLfSGLEELQILELQHNRIKEINDDqFVLCPMLRELNLSANMISTFNMSqLQSLNKL 90
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEEL-ANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEE-LGNLTNL 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  91 ETLDIARNYLDEVFVT----KYLRTLNAQENQISRIVMDQGDFFQLTHLNLSRNNIANINNIFKFRNLIELDVSYNELVT 166
Cdd:COG4886  185 KELDLSNNQITDLPEPlgnlTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTD 264

                        170       180
                 ....*....|....*....|....*
gi 440462244 167 LDFviFAFMKNLKDIKLNNNRLWIL 191
Cdd:COG4886  265 LPP--LANLTNLKTLDLSNNQLTDL 287
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
11-191 3.78e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.88  E-value: 3.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  11 AFDGLGHLRLLYMDENQLEKLPEGLfSGLEELQILELQHNRIKEINDDqFVLCPMLRELNLSANMISTFNMSqLQSLNKL 90
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEEL-ANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEE-LGNLTNL 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  91 ETLDIARNYLDEVFVT----KYLRTLNAQENQISRIVMDQGDFFQLTHLNLSRNNIANINNIFKFRNLIELDVSYNELVT 166
Cdd:COG4886  185 KELDLSNNQITDLPEPlgnlTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTD 264

                        170       180
                 ....*....|....*....|....*
gi 440462244 167 LDFviFAFMKNLKDIKLNNNRLWIL 191
Cdd:COG4886  265 LPP--LANLTNLKTLDLSNNQLTDL 287
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 17-186 1.82e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 52.10  E-value: 1.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  17 HLRLLYMDENQLEKLPEglFSGLEELQILELQHNRIKEINDdqFVLCPMLRELNLSANMISTfnMSQLQSLNKLETLDIA 96
Cdd:cd21340   25 NLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISV--VEGLENLTNLEELHIE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  97 RNYLDE-VFVTKYLRTLNAQENQisrivmdqgdffqLTHLNLSRNNIANINNIFKFRNLIELDVSYNELVTLDFVIFAF- 174
Cdd:cd21340   99 NQRLPPgEKLTFDPRSLAALSNS-------------LRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDLLs 165

                        170
                 ....*....|...
gi 440462244 175 -MKNLKDIKLNNN 186
Cdd:cd21340  166 sWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
17-76 2.47e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 2.47e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244   17 HLRLLYMDENQLEKLPEGLFSGLEELQILELQHNRIKEINDDQFVLCPMLRELNLSANMI 76
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 16-188 1.49e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 47.54  E-value: 1.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  16 GHLRLLYMDENQLE-KLPEGLfSGLEELQILELQHNRIKEINDDQFVLCPMLRELNLSANMISTFNMSQLQSLNKLETLD 94
Cdd:PLN00113 380 GNLFKLILFSNSLEgEIPKSL-GACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLS 458

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  95 IARNY----LDEVFVTKYLRTLNAQENQISRIVMDQ-GDFFQLTHLNLSRNNIANI--NNIFKFRNLIELDVSYNELVTL 167
Cdd:PLN00113 459 LARNKffggLPDSFGSKRLENLDLSRNQFSGAVPRKlGSLSELMQLKLSENKLSGEipDELSSCKKLVSLDLSHNQLSGQ 538

                        170       180
                 ....*....|....*....|.
gi 440462244 168 DFVIFAFMKNLKDIKLNNNRL 188
Cdd:PLN00113 539 IPASFSEMPVLSQLDLSQNQL 559
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
11-191 3.78e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 66.88  E-value: 3.78e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  11 AFDGLGHLRLLYMDENQLEKLPEGLfSGLEELQILELQHNRIKEINDDqFVLCPMLRELNLSANMISTFNMSqLQSLNKL 90
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEEL-ANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPEE-LGNLTNL 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  91 ETLDIARNYLDEVFVT----KYLRTLNAQENQISRIVMDQGDFFQLTHLNLSRNNIANINNIFKFRNLIELDVSYNELVT 166
Cdd:COG4886  185 KELDLSNNQITDLPEPlgnlTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLTD 264

                        170       180
                 ....*....|....*....|....*
gi 440462244 167 LDFviFAFMKNLKDIKLNNNRLWIL 191
Cdd:COG4886  265 LPP--LANLTNLKTLDLSNNQLTDL 287
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
11-191 2.37e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 58.79  E-value: 2.37e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  11 AFDGLGHLRLLYMDENQLEKLPEGLfSGLEELQILELQHNRIKEInDDQFVLCPMLRELNLSANMISTFNMSqLQSLNKL 90
Cdd:COG4886  131 ELANLTNLKELDLSNNQLTDLPEPL-GNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPEP-LGNLTNL 207

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  91 ETLDIARNYLDEVFVT----KYLRTLNAQENQISRIVmDQGDFFQLTHLNLSRNNIANINNIFKFRNLIELDVSYNELVT 166
Cdd:COG4886  208 EELDLSGNQLTDLPEPlanlTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTD 286

                        170       180
                 ....*....|....*....|....*
gi 440462244 167 LDFVIFAFMKNLKDIKLNNNRLWIL 191
Cdd:COG4886  287 LKLKELELLLGLNSLLLLLLLLNLL 311
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 17-186 1.82e-08

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 52.10  E-value: 1.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  17 HLRLLYMDENQLEKLPEglFSGLEELQILELQHNRIKEINDdqFVLCPMLRELNLSANMISTfnMSQLQSLNKLETLDIA 96
Cdd:cd21340   25 NLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISV--VEGLENLTNLEELHIE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  97 RNYLDE-VFVTKYLRTLNAQENQisrivmdqgdffqLTHLNLSRNNIANINNIFKFRNLIELDVSYNELVTLDFVIFAF- 174
Cdd:cd21340   99 NQRLPPgEKLTFDPRSLAALSNS-------------LRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEELLDLLs 165

                        170
                 ....*....|...
gi 440462244 175 -MKNLKDIKLNNN 186
Cdd:cd21340  166 sWPSLRELDLTGN 178
LRR_8 pfam13855
Leucine rich repeat;
17-76 2.47e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.67  E-value: 2.47e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244   17 HLRLLYMDENQLEKLPEGLFSGLEELQILELQHNRIKEINDDQFVLCPMLRELNLSANMI 76
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 1-122 1.70e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.40  E-value: 1.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244   1 NN*IK**EEhaFDGLGHLRLLYMDENQLEKLpEGLfSGLEELQILELQHNRIKEinDDQFV--------LCPMLRELNLS 72
Cdd:cd21340   55 NNQIEKIEN--LENLVNLKKLYLGGNRISVV-EGL-ENLTNLEELHIENQRLPP--GEKLTfdprslaaLSNSLRVLNIS 128

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 440462244  73 ANMISTfnMSQLQSLNKLETLDIARNYL---DEVFVT----KYLRTLNAQENQISRI 122
Cdd:cd21340  129 GNNIDS--LEPLAPLRNLEQLDASNNQIsdlEELLDLlsswPSLRELDLTGNPVCKK 183
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 1-138 2.30e-07

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 49.01  E-value: 2.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244   1 NN*IK**EehAFDGLGHLRLLYMDENQLEKLpEGLfSGLEELQILELQHNRIKEINDdqFVLCPMLREL-----NLSANM 75
Cdd:cd21340   33 DNKITKIE--NLEFLTNLTHLYLQNNQIEKI-ENL-ENLVNLKKLYLGGNRISVVEG--LENLTNLEELhienqRLPPGE 106

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  76 ISTFNMSQLQSL-NKLETLDIARN---YLDEVFVTKYLRTLNAQENQISR---IVMDQGDFFQLTHLNLS 138
Cdd:cd21340  107 KLTFDPRSLAALsNSLRVLNISGNnidSLEPLAPLRNLEQLDASNNQISDleeLLDLLSSWPSLRELDLT 176
LRR_8 pfam13855
Leucine rich repeat;
41-100 3.50e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 45.59  E-value: 3.50e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244   41 ELQILELQHNRIKEINDDQFVLCPMLRELNLSANMISTFNMSQLQSLNKLETLDIARNYL 100
Cdd:pfam13855   2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 16-188 1.49e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 47.54  E-value: 1.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  16 GHLRLLYMDENQLE-KLPEGLfSGLEELQILELQHNRIKEINDDQFVLCPMLRELNLSANMISTFNMSQLQSLNKLETLD 94
Cdd:PLN00113 380 GNLFKLILFSNSLEgEIPKSL-GACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGRINSRKWDMPSLQMLS 458

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  95 IARNY----LDEVFVTKYLRTLNAQENQISRIVMDQ-GDFFQLTHLNLSRNNIANI--NNIFKFRNLIELDVSYNELVTL 167
Cdd:PLN00113 459 LARNKffggLPDSFGSKRLENLDLSRNQFSGAVPRKlGSLSELMQLKLSENKLSGEipDELSSCKKLVSLDLSHNQLSGQ 538

                        170       180
                 ....*....|....*....|.
gi 440462244 168 DFVIFAFMKNLKDIKLNNNRL 188
Cdd:PLN00113 539 IPASFSEMPVLSQLDLSQNQL 559
LRR_8 pfam13855
Leucine rich repeat;
1-52 3.04e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 3.04e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 440462244    1 NN*IK**EEHAFDGLGHLRLLYMDENQLEKLPEGLFSGLEELQILELQHNRI 52
Cdd:pfam13855  10 NNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
1-100 5.08e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 43.15  E-value: 5.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244   1 NN*IK**EEHAFdglGHLRLLYMDENQLEKLPEGLfsgLEELQILELQHNRIKEINDDqfvLCPMLRELNLSANMISTF- 79
Cdd:PRK15370 208 NNELKSLPENLQ---GNIKTLYANSNQLTSIPATL---PDTIQEMELSINRITELPER---LPSALQSLDLFHNKISCLp 278

                         90       100
                 ....*....|....*....|..
gi 440462244  80 -NMSQlqslnKLETLDIARNYL 100
Cdd:PRK15370 279 eNLPE-----ELRYLSVYDNSI 295
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
11-133 1.55e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 41.46  E-value: 1.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  11 AFDGLGHLRLLYMDENQLEKLPEglFSGLEELQILELQHNRIKEINDDQFVlcPMLRELNLSANMISTFNMSQLQSLNKL 90
Cdd:COG4886  223 PLANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLANL--TNLKTLDLSNNQLTDLKLKELELLLGL 298

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 440462244  91 ETLDIARNYLDEVFVTKYLRTLNAQENQISRIVMDQGDFFQLT 133
Cdd:COG4886  299 NSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLA 341
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 31-138 3.56e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 3.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  31 LPEglFSGLEELQILELQHNRIKEINDDQFVLCPMLRELNLSANMISTFNMSQLQSLNKLETLDIARNYLDEVFVTKY-- 108
Cdd:PLN00113 468 LPD--SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFse 545

                         90       100       110
                 ....*....|....*....|....*....|....
gi 440462244 109 ---LRTLNAQENQIS-RIVMDQGDFFQLTHLNLS 138
Cdd:PLN00113 546 mpvLSQLDLSQNQLSgEIPKNLGNVESLVQVNIS 579
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
66-188 6.25e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 36.84  E-value: 6.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 440462244  66 LRELNLSANMISTFNMSQLQSLNKLETLDIARNylDEVFVTKYLRTLNAQENQISRIVMDQGDFFQLTHLNLSRNNIANI 145
Cdd:COG4886   74 LLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN--EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL 151

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 440462244 146 NNIF-KFRNLIELDVSYNELVTLDFVIFAfMKNLKDIKLNNNRL 188
Cdd:COG4886  152 PEPLgNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQI 194
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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