NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|459654424|gb|AGG79074|]
View 

NADH dehydrogenase subunit 4, partial (mitochondrion) [Drosophila melanogaster]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-153 2.66e-52

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00163:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 445  Bit Score: 171.49  E-value: 2.66e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   1 INKHNNYKNLFLLNIIILLLLLILTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGI 80
Cdd:MTH00163  79 VYKKNNYSNLFLFLILFLLIFLLLTFSSMNLLLFYIFFESSLIPTLFLILGWGYQPERLQAGIYLLFYTLFASLPLLVGI 158

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 459654424  81 FYVMNKIGSMNFYLMNNFMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00163 159 FYLYNNSGSLSFFLLNFFGSLNFLWYLSMILAFLVKMPMFFVHLWLPKAHVEAPVSGSMILAGVLLKLGGYGL 231
 
Name Accession Description Interval E-value
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-153 2.66e-52

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 171.49  E-value: 2.66e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   1 INKHNNYKNLFLLNIIILLLLLILTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGI 80
Cdd:MTH00163  79 VYKKNNYSNLFLFLILFLLIFLLLTFSSMNLLLFYIFFESSLIPTLFLILGWGYQPERLQAGIYLLFYTLFASLPLLVGI 158

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 459654424  81 FYVMNKIGSMNFYLMNNFMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00163 159 FYLYNNSGSLSFFLLNFFGSLNFLWYLSMILAFLVKMPMFFVHLWLPKAHVEAPVSGSMILAGVLLKLGGYGL 231
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 25-153 2.84e-32

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 119.03  E-value: 2.84e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYqPERLQAGLYLLFYTLLVSLPMLIGIF--YVMNKIGSMNFYLMNNFMFNY 102
Cdd:COG1008  127 VFLALDLFLFYVFWELMLIPMYFLIGIWGG-ERRIYAAIKFFLYTLAGSLLMLVAILalYFLAGALTFDIAELAAAPLPL 205

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 459654424 103 D---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:COG1008  206 TaqlLLFLAFFIAFAVKVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLKMGGYGL 259
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 28-152 4.82e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 99.70  E-value: 4.82e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   28 SMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYD---- 103
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 459654424  104 --LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYG 152
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYG 131
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 25-153 1.35e-25

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 100.78  E-value: 1.35e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   25 TFSSMSLFMFYLFFESSLIPTLFLILGWGyQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIG-SMNFYLMNNFMFNYD 103
Cdd:TIGR01972 122 VFLALDLFLFYVFWEAMLIPMYLLIGVWG-GPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgTFDLLELLNLPLPFG 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 459654424  104 ---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:TIGR01972 201 vqtWLFLAFFIAFAVKVPLFPLHTWLPDAHVEAPTAGSVILAGVLLKMGTYGF 253
 
Name Accession Description Interval E-value
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-153 2.66e-52

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 171.49  E-value: 2.66e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   1 INKHNNYKNLFLLNIIILLLLLILTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGI 80
Cdd:MTH00163  79 VYKKNNYSNLFLFLILFLLIFLLLTFSSMNLLLFYIFFESSLIPTLFLILGWGYQPERLQAGIYLLFYTLFASLPLLVGI 158

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 459654424  81 FYVMNKIGSMNFYLMNNFMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00163 159 FYLYNNSGSLSFFLLNFFGSLNFLWYLSMILAFLVKMPMFFVHLWLPKAHVEAPVSGSMILAGVLLKLGGYGL 231
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 25-153 6.08e-49

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 162.32  E-value: 6.08e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLM---NNFMFN 101
Cdd:MTH00150  71 AFSVSSLLMFYFFFEASLIPTLLLILGWGYQPERLQAGMYMMLYTVGASLPLLLVILWMSSSYGSSFMLLIsslRKLLSS 150

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 459654424 102 YDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00150 151 MGLWGLLVFLAFLVKLPMYPFHLWLPKAHVEAPVAGSMILAGILLKLGGYGI 202
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 25-153 1.08e-47

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 159.59  E-value: 1.08e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLM---NNFMFN 101
Cdd:MTH00124 109 AFSATELTLFYIMFEATLIPTLILITRWGNQPERLSAGTYFLFYTLISSLPLLIAILYLHNQTGTLSLPMLqltHPTLTN 188

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 459654424 102 Y---DLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00124 189 SwtnLLLWLACLMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGI 243
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 25-153 3.09e-46

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 155.82  E-value: 3.09e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMN------NF 98
Cdd:MTH00110 109 TFTATELIMFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLVGSLPLLVALLYIQNNLGSLNFLLLQlwaqplPN 188

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 459654424  99 MFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00110 189 SWSNNLLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAILLKLGGYGM 243
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 26-153 1.62e-44

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 151.61  E-value: 1.62e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDLL 105
Cdd:MTH00068 110 FSATELILFYIFFEATLIPTLIIITRWGNQEERLNAGTYFLFYTLAGSLPLLIALLILQNSLGSLSLILLELMSPMQLMT 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 459654424 106 Y-------FCLLcAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00068 190 YtnkiwwlACLL-AFMVKMPLYGLHLWLPKAHVEAPIAGSMILAAVLLKLGGYGI 243
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 5-153 2.53e-43

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 148.35  E-value: 2.53e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   5 NNYKNLFLLNIIILLLLLILTFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVM 84
Cdd:MTH00014  86 NKAPKTFMTNILILNLILLLTFSASNLLMFYIFFEASLIPTLFLILGWGYQPERLQASFYLMIYTVTASLPLLMSILLIF 165

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 459654424  85 NKIGSMNFYLMN---NFMFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00014 166 YTNNSLSMLMSSmepPSIYLMNLWWLITILAFMVKMPLYTVHLWLPKAHVEAPVAGSMILAGILLKLGGYGL 237
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 25-153 3.67e-43

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 147.82  E-value: 3.67e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYD- 103
Cdd:MTH00205 104 SFSVDNLLLFYITFEASLIPTLILILGWGYQPERLQASMYMMMYTLCASLPLLIGLFFLNSLNFSLSMFFNFPLNFSDFy 183

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 459654424 104 --LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00205 184 lfLYWIFLMLAFLVKLPMYFVHLWLPKAHVEAPVSGSMILAGVLLKLGGYGL 235
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 25-153 2.99e-42

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 145.50  E-value: 2.99e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMN------NF 98
Cdd:MTH00044 110 TFSSLELILFYIAFETTLIPTLILITRWGAQKERIQAGLYFLFYTLFGSLPLLISLIAIYSSSSSLSIPLSElnwltsLS 189

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 459654424  99 MFNYDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00044 190 SNSSSIWWIFCILAFLVKMPIYGFHLWLPKAHVEAPVAGSMILAAILLKLGGYGL 244
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 25-153 3.55e-37

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 131.99  E-value: 3.55e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLM---NNFMFN 101
Cdd:MTH00206 108 FFSSSNLLLFYILFEASLIPTLLLITRWGNQKERLNAGYYFLFYTLIGSLPLLIALLFLQNSLGSLSLYILyfsKLTTWN 187

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 459654424 102 YDLLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00206 188 NNLWWLACILAFLVKLPLYGVHLWLPKAHVEAPVAGSMVLAGVLLKLGGYGM 239
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 26-153 6.72e-34

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 123.14  E-value: 6.72e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDLL 105
Cdd:MTH00127 111 FGATEIIMFYVMFEATLIPTLIIITRWGNQTERLNAGTYFLFYTLAGSLPLLVALLLLQNSTGTLSMLTLQYSQPLQLSS 190

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 459654424 106 YF-------CLLcAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00127 191 WAdklwwagCLL-AFLVKMPLYGVHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGM 244
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 26-153 2.77e-32

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 119.15  E-value: 2.77e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYqPERLQAGLYLLFYTLLVSLPMLIGIFYV----MNKIGSMNFYLMNNFMFN 101
Cdd:PRK05846 128 FAALDLLLFYVFFEAMLIPMYFLIGVWGG-KNRIYAATKFFLYTLLGSLLMLVAIIYLvvvyYNATGTFDIADLLNLPLP 206

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 459654424 102 YD---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK05846 207 PGvqyWLFLAFFIAFAVKMPMFPLHTWLPDAHVQAPTAGSVLLAGILLKMGAYGL 261
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 25-153 2.84e-32

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 119.03  E-value: 2.84e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYqPERLQAGLYLLFYTLLVSLPMLIGIF--YVMNKIGSMNFYLMNNFMFNY 102
Cdd:COG1008  127 VFLALDLFLFYVFWELMLIPMYFLIGIWGG-ERRIYAAIKFFLYTLAGSLLMLVAILalYFLAGALTFDIAELAAAPLPL 205

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 459654424 103 D---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:COG1008  206 TaqlLLFLAFFIAFAVKVPMFPFHTWLPDAHVEAPTAGSVLLAGVLLKMGGYGL 259
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 26-153 1.41e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 111.69  E-value: 1.41e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDLL 105
Cdd:MTH00204 129 FSVLDLLLFYILFEGILIPMFLLIGIWGSREEKVRASYYFFFYTFAGSVFMLLGIFQLYSITGTTDYQILLNIKLPLSIQ 208

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 459654424 106 YFCLLCAFL---VKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00204 209 KWLLVGFFLslaVKIPQIPFHIWLPQAHVEAPVAGSVILAGILLKLGGYGF 259
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 26-152 2.61e-29

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 110.91  E-value: 2.61e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPtLFLILG-WGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDL 104
Cdd:MTH00217 126 FTILDLVGFYILFEGILIP-MFLIIGiWGSREEKVQASYYFFFYTFIGSVFMLLGIFTLYSYAGTTDYQALCCLKIEKEL 204

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 459654424 105 LYFCLLCAFL---VKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYG 152
Cdd:MTH00217 205 QYFIFLGFFLslaIKIPKIPFHIWLPQAHVEAPVAGSVILAGVLLKLGGYG 255
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 28-152 4.82e-26

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 99.70  E-value: 4.82e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   28 SMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYD---- 103
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 459654424  104 --LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYG 152
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAATLVKAGGYG 131
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 25-153 1.35e-25

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 100.78  E-value: 1.35e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424   25 TFSSMSLFMFYLFFESSLIPTLFLILGWGyQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIG-SMNFYLMNNFMFNYD 103
Cdd:TIGR01972 122 VFLALDLFLFYVFWEAMLIPMYLLIGVWG-GPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgTFDLLELLNLPLPFG 200

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 459654424  104 ---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:TIGR01972 201 vqtWLFLAFFIAFAVKVPLFPLHTWLPDAHVEAPTAGSVILAGVLLKMGTYGF 253
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 26-153 1.36e-25

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 100.77  E-value: 1.36e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPtLFLILG-WGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLM--NNFMFNY 102
Cdd:MTH00226 148 FSVLDIFMFYILFEGVLIP-MYLILGiWGSREEKMQAAYYFFFYTLIGSVLMLLCLFSLYNIHGTTDYLTLasCSHVVSE 226

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 459654424 103 DL---LYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:MTH00226 227 QTqkwIFLGIFLAMAVKIPIFPFHIWLPKAHVEAPVAGSVLLAGILLKLGGYGL 280
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 26-152 5.41e-21

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 87.65  E-value: 5.41e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNkigsMNFYLMNNFMFNYDLL 105
Cdd:MTH00094  79 FVSSNMLMLYMFFELSMFPILIMILGYGSQIEKINSSYYLLFYAAFFSFPFLFVYLKNFF----FFSLCYFDFFLSWEMF 154

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 459654424 106 YFCLLCaFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYG 152
Cdd:MTH00094 155 FILSLS-FMMKFPVYFLHLWLPKAHVEAPTTASMLLAGLLLKLGTAG 200
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 26-153 1.87e-20

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 86.24  E-value: 1.87e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQpERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYD-- 103
Cdd:PRK12561 104 FLAQDLLLFFLMWELELVPVYLLISIWGGQ-KRLYAATKFILYTALASIFILVAGLALALSGDTFTFDLAELGAKSYPla 182

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 459654424 104 ---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK12561 183 lelLLYAGFLIAFGVKLPIFPLHTWLPDAHGEASAPVSMILAGVLLKMGGYAL 235
ndhD CHL00011
NADH dehydrogenase subunit 4
 26-153 3.94e-17

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 76.91  E-value: 3.94e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQpERLQAGLYLLFYTLLVSLPMLIGIFyvmnkigSMNFYLMNNFMFNYD-- 103
Cdd:CHL00011 129 FSSRDLLLFFIMWELELIPVYLLLSMWGGK-KRLYSATKFILYTAGGSIFLLIGVL-------GMGLYGSNEPTLNFEtl 200

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 459654424 104 -----------LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:CHL00011 201 anqsypvaleiLFYIGFLIAYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGL 261
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 31-153 7.55e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 75.95  E-value: 7.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  31 LFMFYLFFESSLIPTLFLILGWGYqPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYD-----LL 105
Cdd:COG0651  129 LFNLFVFFEVMLLASYGLVALGGT-KEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAELDpglllAA 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 459654424 106 YFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:COG0651  208 FALLLVGFGIKAALFPLHFWLPDAYPAAPSPVSALLSGLLTKVGVYAI 255
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
26-153 6.85e-16

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 73.20  E-value: 6.85e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQpERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYD-- 103
Cdd:PRK06473 124 FLAQDLLLFFLFYELELIPLYLLIAIWGGQ-RRGYAATKFLLYTAISGILILVSFLGLVWLSGASSFDYEPLRSHTLPls 202

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 459654424 104 ---LLYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK06473 203 tqlLLLAPILVGFGIKIPLVPFHTWLPDAHVEASTPVSVLLAGVLLKLGTYGL 255
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 26-153 5.25e-15

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 70.89  E-value: 5.25e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQpERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMN----NFMFN 101
Cdd:PRK02546 132 FAVQDMLLFFLAWELELIPVYLLLAIWGGK-KRQYAATKFILYTAGSSLFILLAALAMAFYGDTPTFDMTAlaakDFGLG 210

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 459654424 102 YDLL-YFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK02546 211 FQLLcYAGLLIAYGVKLPIVPLHTWLPDAHGEATAPVHMLLAGILLKMGGYAL 263
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 25-149 6.31e-14

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 67.64  E-value: 6.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDL 104
Cdd:MTH00062  87 CFCVNNSLLFWFFYELSIIPLLYLLFSESPYSERYLASWYFLGYLLLTSLPLLLCLLYLSLVNGSFNFSDWGSDDSVSLI 166

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 459654424 105 LYFCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLG 149
Cdd:MTH00062 167 VYYVLSFMFITKVPLFPFHTWLPIVHAEASSPVSIFLSGYIMKLG 211
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
26-153 6.34e-11

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 58.96  E-value: 6.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILGWGYQpERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMN----NFMFN 101
Cdd:PRK07363 124 LLAQNLLLFFLFYELELIPFYLLIAIWGGE-KRGYASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFDYDAistqNLSLN 202

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 459654424 102 YDLLYFC-LLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK07363 203 TQLILLTgLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGGVLAKLGTYGL 255
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 26-153 4.69e-09

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 53.85  E-value: 4.69e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  26 FSSMSLFMFYLFFESSLIPTLFLILgWGYQPERLQAGLYLLFyTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFN---- 101
Cdd:PRK08668 115 FLANDLLTLYIFWEIMTFSSFMMVP-MGKKESRKASLKYFVL-SAIGAYAMLYAIFLIYAKTGTFDFADISQGLINdtst 192

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 459654424 102 -YDLLYFCLLCAF-LVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK08668 193 gFALIVFLFLLAFgVAKAGIFPLHVWAPDAYSEAPQSFSAVLSGQLSKLGAYGF 246
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 31-153 3.90e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.03  E-value: 3.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  31 LFMFYLFFESSLIPTLFLIlGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLM-NNFMFNYDL---LY 106
Cdd:PRK08375 128 LFNLFVFLEIMSLSSYALV-AMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLaGALAENPTVvtaFG 206

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 459654424 107 FCLLcAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK08375 207 FVLL-ALALKAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVYAL 252
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 28-153 2.13e-07

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 48.96  E-value: 2.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  28 SMSLFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDLLYF 107
Cdd:PRK08667 130 SANTFSFLFFWEIMALSSFFLVMNDYQEEETQRAGIFYFVMTQLSTVFLMLGIIVLFIQTGSFELSPLGASAGILSLVFL 209

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 459654424 108 CLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK08667 210 LLFLGFGIKAGIIPFHKWLPYAHPASPSNVSALMSGVMLKVAVYGL 255
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 25-153 1.84e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 46.10  E-value: 1.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  25 TFSSMSLFMFYLFFESSLIPTlFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNfmfnYDL 104
Cdd:PRK07234 110 AFVCADLISLYVALEVLSIAT-FLLVAYPRTDRAIWVGLRYLFYSNVAMLFYLIGAVLVYQANGTFAFSGLAT----ADP 184

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 459654424 105 LYFCLLCA-FLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK07234 185 EAFALIALgLLVKGGIFVSGLWLPLTHSEAEPPVSALLSGVVVKAGVFPL 234
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 31-141 3.69e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 42.39  E-value: 3.69e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  31 LFMFYLFFESSLIPTLFLILGWGYQPERLQAGLYLLFYTLLVSLPMLIGIFYVMNKIGSMNF----YLMNNFMFNYDLLY 106
Cdd:PRK08376 143 LFNFFVFLEIMSIASYALVAFRNDTWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYGTLNMaylaVKMSENPTVVAKIA 222

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 459654424 107 FCLLCA-FLVKMPMFLVHLWLPKAHVEAPVSGSMIL 141
Cdd:PRK08376 223 LALFIAgLAMKSGAVPVHMWLPDAYPAAPSSISAML 258
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 28-149 8.76e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 41.34  E-value: 8.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 459654424  28 SMSLFMFYLFFESSLIPTLFLIlGWGYQPERLQAGL-YLLFYTLLVSLPMLIGIFYVMNKIGSMNFYLMNNFMFNYDLLY 106
Cdd:PRK06589 135 SSDLFTMFVCYELLTISTAFLI-GHTRNNISLSGGYkYLKILMISALLLFLPAVILIYTKTGNLDFVSGGLFSKNQSIIL 213

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 459654424 107 FCLLCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLG 149
Cdd:PRK06589 214 LLMFIYGIAKTAIFPVHSWLPAAMVAHYPVSALLHAVIVVKTG 256
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 112-153 1.45e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 40.72  E-value: 1.45e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 459654424 112 AFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK12667 232 AFTIKAAIFPNHFWLPDAHPAAPSPVSAMLSGLVVNVGAYAI 273
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 110-153 1.63e-03

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 37.56  E-value: 1.63e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 459654424 110 LCAFLVKMPMFLVHLWLPKAHVEAPVSGSMILAGIMLKLGGYGM 153
Cdd:PRK06521 217 LFGFGAKAGLVPLHVWLPRAHPAAPSHVSALMSGVMLKVAIYGI 260
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH