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Conserved domains on  [gi|576733507|gb|AHH33333|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Platyrhina tangi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 4.48e-151

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 428.84  E-value: 4.48e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00135   2 NPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLyHLLNSDLLLIMGISS 160
Cdd:MTH00135  82 GQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPYQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTLTT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 4.48e-151

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 428.84  E-value: 4.48e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00135   2 NPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLyHLLNSDLLLIMGISS 160
Cdd:MTH00135  82 GQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPYQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTLTT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 3-299 1.07e-16

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 80.55  E-value: 1.07e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   3 LILFILisslgLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQ-QHPRAVEASTKYFLT*******LLFAGTMNAWLTG 81
Cdd:COG1007  107 LLLFAT-----LGMMLMASANDLLTLFLGLELLSLSLYVLVAFRrDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATG 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  82 QWNITEMTNFTSTT------------LITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLN 149
Cdd:COG1007  182 SLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAF 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 150 SDLLLIMGISSIIIGGW-------GGLNQTQLRKILAYSSIAHLGWMITIL----HYAPNLTLLNLILYIIMTTSMFLLF 218
Cdd:COG1007  262 PGLAADWQLLLAVLAVLsmtvgnlAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAFAVI 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 219 -----KMFNCTKINSITPSTSKSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYL 293
Cdd:COG1007  342 lllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYL 421


                 ....*.
gi 576733507 294 RLSYSM 299
Cdd:COG1007  422 RVVKAM 427
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-285 2.22e-16

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 78.12  E-value: 2.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   23 THWLLIWMGLEINTMAIIPMMIY-QQHPRAVEASTKYFLT*******LLFAGTMNAWLTGQWNITEM-----------TN 90
Cdd:pfam00361   2 NDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   91 FTSTTLITIALALKIGLAPMHFWLPEVIQGLSL-ITGLVLSTWQKLAPFAVLLQLYHLLNSD-----LLLIMGISSIIIG 164
Cdd:pfam00361  82 LLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLIRRSLLYLPSSpfiqqILLILAIISMLLG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  165 GWGGLNQTQLRKILAYSSIAHLGWMITIL----HYAPNLTLLNLILYIIMTTSMFLLFKMFNC----TKINSITPSTSKS 236
Cdd:pfam00361 162 SLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYrrvhTRNIRDYGGLAKT 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 576733507  237 -PLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALAT 285
Cdd:pfam00361 242 mPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 3-299 7.01e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 72.29  E-value: 7.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507    3 LILFILISSLGLGTTITflGTHWLLIWMGLEINTMAIIPMMIYQ-QHPRAVEASTKYFLT*******LLFAGTMNAWLTG 81
Cdd:TIGR01770 104 FYILLLFALLGIFLLVS--SNDLLSIYLGLELQSLCFYVLAGLKrKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   82 QWNITEMTNFTSTT------------LITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLY---- 145
Cdd:TIGR01770 182 SLNFEDLLLFLSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyil 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  146 ---HLLNSDLLLIMGISSIIIGGWGGLNQTQLRKILAYSSIAHLGWMITILhYAPNL-----TLLNLILYIIMTTSMFLL 217
Cdd:TIGR01770 262 fgfSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGL-LAGTLegikaVLFYIFIYALMSLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  218 FKMFNCTKINSITPSTSKS------PLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFF 291
Cdd:TIGR01770 341 LSLLRSYKDEWIEYISDFAglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420


                  ....*...
gi 576733507  292 YLRLSYSM 299
Cdd:TIGR01770 421 YLRVVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-347 4.48e-151

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 428.84  E-value: 4.48e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00135   2 NPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLyHLLNSDLLLIMGISS 160
Cdd:MTH00135  82 GQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPYQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320

                        330       340
                 ....*....|....*....|....*..
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTLTT 347
Cdd:MTH00135 321 LTLPLAISTTATLMLLPLTPAILALLT 347
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-345 9.41e-125

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 361.93  E-value: 9.41e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00070   2 SPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISS 160
Cdd:MTH00070  82 GEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00070 162 TLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPyQ 320
Cdd:MTH00070 242 SMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKN-K 320

                        330       340
                 ....*....|....*....|....*
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTL 345
Cdd:MTH00070 321 TNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-346 2.15e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 332.94  E-value: 2.15e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00112   2 NPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISS 160
Cdd:MTH00112  82 GQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00112 162 TLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLN 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPYQ 320
Cdd:MTH00112 242 TTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKK 321

                        330       340
                 ....*....|....*....|....*.
gi 576733507 321 pNPILATTASISTLLLPLTPMMYTLT 346
Cdd:MTH00112 322 -NTLTATLTTLSTLLLPLSPMILTII 346
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-346 7.59e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 326.42  E-value: 7.59e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00105   2 NPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISS 160
Cdd:MTH00105  82 GQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00105 162 ILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMT 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPYQ 320
Cdd:MTH00105 242 SLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTK 321

                        330       340
                 ....*....|....*....|....*.
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTLT 346
Cdd:MTH00105 322 PMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-347 9.84e-101

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 300.73  E-value: 9.84e-101
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00200   2 SPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISS 160
Cdd:MTH00200  82 GQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00200 162 VLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILS 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKPYq 320
Cdd:MTH00200 242 MLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN- 320

                        330       340
                 ....*....|....*....|....*..
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTLTT 347
Cdd:MTH00200 321 SNLLVGLLLLLSILGLPLTPQLLFLFF 347
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-339 8.26e-73

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 229.43  E-value: 8.26e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLT 80
Cdd:MTH00041   2 NRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 GQWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISS 160
Cdd:MTH00041  82 GSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILS 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00041 162 VLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISA 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWR----T 316
Cdd:MTH00041 242 FLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRnsgnI 321

                        330       340
                 ....*....|....*....|....
gi 576733507 317 KPYQP-NPILATTASISTLLLPLT 339
Cdd:MTH00041 322 TVYGViLSILSSISILGLLLIPLF 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-345 8.84e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 161.53  E-value: 8.84e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   1 NPLILFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAwlt 80
Cdd:MTH00160   3 MNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNM--- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  81 gqwNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLlqlYHLLNSDLLLIMGISS 160
Cdd:MTH00160  80 ---LNLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILL---SYLINNNFIIIIIILS 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 161 IIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLT 240
Cdd:MTH00160 154 AIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIK 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 241 IIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSwrtKPYQ 320
Cdd:MTH00160 234 FLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKK---KKNK 310

                        330       340
                 ....*....|....*....|....*
gi 576733507 321 PNPILATTASISTLLLPLTPMMYTL 345
Cdd:MTH00160 311 FSLILNFLSFISLFGLILSSLLFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-318 9.37e-41

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 145.41  E-value: 9.37e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   4 ILFILISslGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLTGQW 83
Cdd:MTH00144   7 LLFLFLM--VMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  84 NitemtnftSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISSIII 163
Cdd:MTH00144  85 F--------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLAYLLCVISVLSAL 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 164 G-GWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITpSTSKSPLLTII 242
Cdd:MTH00144 157 VgSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLG-SLKPSYKTGLS 235

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 576733507 243 ALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLTISPNTTPSLSSWRTKP 318
Cdd:MTH00144 236 IISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSS 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-340 1.59e-36

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 134.52  E-value: 1.59e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   5 LFILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMnawltgQWN 84
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MWS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  85 ITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSDLLLIMGISSIIIG 164
Cdd:MTH00011  82 FPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 165 GWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLTIIAL 244
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 245 TTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSMTLtispnTTPSLSSWRTKPYQPNPI 324
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMY-----LSPTFSSLKSAPYEPKTK 316

                        330
                 ....*....|....*.
gi 576733507 325 LATtaSISTLLLPLTP 340
Cdd:MTH00011 317 ILI--SMCTLSLGLIP 330
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 6-298 3.78e-30

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 117.08  E-value: 3.78e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   6 FILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGtmnaWLTGQWNI 85
Cdd:MTH00197   1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGG----SLSFSNLY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  86 TEMTnftSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHllNSDLLLIMGISSIIIGG 165
Cdd:MTH00197  77 LSLL---SVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS--SFMGLLICSVLSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 166 WGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYIIMTTSMFLLFKMFNCTKINSITPSTSKSPLLTIIALT 245
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 576733507 246 TLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYS 298
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYK 284
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 3-299 1.07e-16

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 80.55  E-value: 1.07e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   3 LILFILisslgLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQ-QHPRAVEASTKYFLT*******LLFAGTMNAWLTG 81
Cdd:COG1007  107 LLLFAT-----LGMMLMASANDLLTLFLGLELLSLSLYVLVAFRrDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATG 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  82 QWNITEMTNFTSTT------------LITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLN 149
Cdd:COG1007  182 SLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAF 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 150 SDLLLIMGISSIIIGGW-------GGLNQTQLRKILAYSSIAHLGWMITIL----HYAPNLTLLNLILYIIMTTSMFLLF 218
Cdd:COG1007  262 PGLAADWQLLLAVLAVLsmtvgnlAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAFAVI 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 219 -----KMFNCTKINSITPSTSKSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYL 293
Cdd:COG1007  342 lllsrKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYL 421


                 ....*.
gi 576733507 294 RLSYSM 299
Cdd:COG1007  422 RVVKAM 427
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 3-295 1.64e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 80.06  E-value: 1.64e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   3 LILFILISSLGLGTTItflgtHWLLIWMGLEINTMAI-IPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLTG 81
Cdd:MTH00199 102 LILIVALGSLLLVSSI-----NWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTG 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  82 QWNITEMTNFTST----TLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNsdLLLIMG 157
Cdd:MTH00199 177 ETSIQGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICA 254

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 158 ISSIIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPN----LTLLNLILYIIMTTSMFLLFKMFNCTK--INSITP 231
Cdd:MTH00199 255 VLSIIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSFesiqASLIYMIIYVIMSICSFSIILSLKLTKglIVEVSG 334

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 576733507 232 STSKSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRL 295
Cdd:MTH00199 335 LSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-285 2.22e-16

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 78.12  E-value: 2.22e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   23 THWLLIWMGLEINTMAIIPMMIY-QQHPRAVEASTKYFLT*******LLFAGTMNAWLTGQWNITEM-----------TN 90
Cdd:pfam00361   2 NDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELskaltgglnssGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   91 FTSTTLITIALALKIGLAPMHFWLPEVIQGLSL-ITGLVLSTWQKLAPFAVLLQLYHLLNSD-----LLLIMGISSIIIG 164
Cdd:pfam00361  82 LLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTpVSALLAATLVKAGGYGLIRRSLLYLPSSpfiqqILLILAIISMLLG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  165 GWGGLNQTQLRKILAYSSIAHLGWMITIL----HYAPNLTLLNLILYIIMTTSMFLLFKMFNC----TKINSITPSTSKS 236
Cdd:pfam00361 162 SLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYrrvhTRNIRDYGGLAKT 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 576733507  237 -PLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALAT 285
Cdd:pfam00361 242 mPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 14-295 3.24e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 75.84  E-value: 3.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  14 LGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHP-RAVEASTKYFLT*******LLFAGTMNAWLTG----------- 81
Cdd:MTH00196   4 LGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGglhlsyinlvl 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  82 --QWNITEMTNFTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYhlLNSDLLLIMGIS 159
Cdd:MTH00196  84 nsGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIG--LNVNILLIGGLF 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 160 SIIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAP----NLTLLNLILYIIMTTSMFLLFKMFNCTK--INSITPST 233
Cdd:MTH00196 162 SLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYKnlIIEFSGLS 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 576733507 234 SKSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRL 295
Cdd:MTH00196 242 RRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
7-341 2.99e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 73.32  E-value: 2.99e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   7 ILISSLGLGTTITflGTHWLLIWMGLEINTMAI-IPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLTGQWNI 85
Cdd:PRK05777 109 VLFALLGMMVMVS--ANDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSF 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  86 TEMTNFTSTT------------LITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLL----- 148
Cdd:PRK05777 187 AGIAKALADGsgnsllllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLVVAfggls 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 149 --NSDLLLIMGISSIIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNL----TLLNLILYIIMTTSMF-----LL 217
Cdd:PRK05777 267 edWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGAFgvislLR 346

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 218 FKMFNCTKINSITPSTSKSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSY 297
Cdd:PRK05777 347 RKGGEAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIK 426

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 576733507 298 SMTLTISPNTTPSlsswrTKPYQPNPILATTASISTLLLPLTPM 341
Cdd:PRK05777 427 LMYFDEPPRDAPV-----NWPLSAGGAVLSVSALLVLVLGIFPQ 465
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 3-299 7.01e-14

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 72.29  E-value: 7.01e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507    3 LILFILISSLGLGTTITflGTHWLLIWMGLEINTMAIIPMMIYQ-QHPRAVEASTKYFLT*******LLFAGTMNAWLTG 81
Cdd:TIGR01770 104 FYILLLFALLGIFLLVS--SNDLLSIYLGLELQSLCFYVLAGLKrKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTG 181

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   82 QWNITEMTNFTSTT------------LITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLY---- 145
Cdd:TIGR01770 182 SLNFEDLLLFLSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyil 261

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  146 ---HLLNSDLLLIMGISSIIIGGWGGLNQTQLRKILAYSSIAHLGWMITILhYAPNL-----TLLNLILYIIMTTSMFLL 217
Cdd:TIGR01770 262 fgfSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGL-LAGTLegikaVLFYIFIYALMSLGAFGV 340

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  218 FKMFNCTKINSITPSTSKS------PLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFF 291
Cdd:TIGR01770 341 LSLLRSYKDEWIEYISDFAglfktnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFY 420


                  ....*...
gi 576733507  292 YLRLSYSM 299
Cdd:TIGR01770 421 YLRVVKVM 428
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 2-299 1.06e-09

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 59.39  E-value: 1.06e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   2 PLILFILISSLGLgttitFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLTG 81
Cdd:COG0651  111 PLFLLLLAGMNGA-----FLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATG 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  82 QWNITEMTNFTST----------TLITIALALKIGLAPMHFWLPEV-----IQGLSLITGLVLstwqKLAPFAVLLQLYH 146
Cdd:COG0651  186 TLNMADLAARLAEldpglllaafALLLVGFGIKAALFPLHFWLPDAypaapSPVSALLSGLLT----KVGVYAILRVLTL 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 147 LLNSDLLLIMGISSIIIGG-------WGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYII----MTTSMF 215
Cdd:COG0651  262 LFGADPALFLGTLLLVLGLltmlvgaLGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhalAKALLF 341

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 216 L----LFKMFNCTKINSITPSTSKSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFF 291
Cdd:COG0651  342 LaagaIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAY 421


                 ....*...
gi 576733507 292 YLRLSYSM 299
Cdd:COG0651  422 FVRIFGRA 429
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 6-190 7.30e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 57.18  E-value: 7.30e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   6 FILISSLGLGTTITFLGTHWLLIWMGLEINTMAIIPMMIYQQHPRAV---------EASTKYFLT*******LLFAGTMN 76
Cdd:MTH00198 191 FALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALY 270

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  77 AWLTGqwNITEMTNFTSTTL----------------ITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAV 140
Cdd:MTH00198 271 FGFTG--NEGMLGTILSATLettnielrqgslgylfITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYIL 348

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 576733507 141 LLQLyhLLNSDLLLIMGISSIIIGGWGGLNQTQLRKILAYSSIAHLGWMI 190
Cdd:MTH00198 349 LTSL--VITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-340 5.50e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 48.79  E-value: 5.50e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 576733507  290 FFYLRLSYSMTLTISPNTTPSLSSWRTKPYQPNPILATTASISTLLLPLTP 340
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 32-297 1.06e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.18  E-value: 1.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  32 LEINTMAIIPMMIYQQHPRAVEASTKYFLT*******LLFAGTMNAWLTGQWNITEMTN--------FTSTTLITIALAL 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGalaenptvVTAFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 104 KIGLAPMHFWLPEVIQGLSLITGLVLS-TWQKLAPFAVLLQLYH---------LLNSDLLLIMGISSIIIGGWGGLNQTQ 173
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIRIYFTvfggdfrfaLGLGWLLAVLALLSMLVGSLAALGQDD 294

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 174 LRKILAYSSIAHLGWMITILHYAPNLTLLNLILYI----IMTTSMFLLFKMFNCT----KINSITPSTSKSPLLTIIALT 245
Cdd:PRK08375 295 VKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLlhhaLMKGALFLAAGAIEVTygtrRLSELSGLGRRMPLTAAAFAV 374

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 576733507 246 TLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSY 297
Cdd:PRK08375 375 ASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 43-299 4.97e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 44.96  E-value: 4.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  43 MIYQQHPRAVEASTKYFLT*******LLFA--------GTMN----AWLTGQWNITEMTNFTSTTLITIALAL------- 103
Cdd:PRK12667 154 AYYRDRGDAVEAAIKYALIGAVGTTLYFLAlaflyatfGTLNmadlSAKIRGLSFPLTGGLAGNPPLALGVALalalwaf 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 104 --KIGLAPMHFWLPEVIQGL-----SLITGLVLstwqKLAPFAVLLQLYHLLNSDLLLIMGISSIIIGGWGG-------- 168
Cdd:PRK12667 234 tiKAAIFPNHFWLPDAHPAApspvsAMLSGLVV----NVGAYAIIRFLYTIFGISPSLIDFRAALSPILIILgavsaiig 309

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507 169 ----LNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYII----------MTTSMFLlfKMFNCTKINSITPSTS 234
Cdd:PRK12667 310 almmVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksllfLASGVFI--HAAGTRDIDELAGLGR 387

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 576733507 235 KSPLLTIIALTTLLSLGGLPPLSGFLPKWLILQELTKQNLILPATIMALATLLSLFFYLRLSYSM 299
Cdd:PRK12667 388 KMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSL 452
ndhB CHL00049
NADH dehydrogenase subunit 2
 86-216 6.59e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 38.06  E-value: 6.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  86 TEMTN----FTSTTLITIALALKIGLAPMHFWLPEVIQGLSLITGLVLSTWQKLAPFAVLLQLYHLLNSD-------LLL 154
Cdd:CHL00049 205 TQMYNspgiSIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFssnewhlLLE 284

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 576733507 155 IMGISSIIIGGWGGLNQTQLRKILAYSSIAHLGW-MITILHYAPNLTLLNLILYIIMTTSMFL 216
Cdd:CHL00049 285 ILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYIFMNL 347
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 4-209 8.46e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 37.81  E-value: 8.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507   4 ILFILISSLGLGTTITFLGTHWLLIWMGLEINTMaIIPMMIYQQHPRA-VEASTKYFLT*****------**LLFAGTMN 76
Cdd:PRK08676 103 VFYLGFNLLLSVITFAFFSDNLALFWIFAELTTV-FSAMLIAILSAREnIDAALKYIFIASTAMifafigLIFLFSLTRQ 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 576733507  77 AWLTGQWNITEMTN----------FTSTTLITIALALKIGLAPMHFWLPEV-IQGLSLITGLVLSTWQKLAPFAVLlQLY 145
Cdd:PRK08676 182 ALGTGTLNWTELAAhasllspsvlGASFLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGIL-RLS 260

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 576733507 146 HLLN--------SDLLLIMGISSIIIGGWGGLNQTQLRKILAYSSIAHLGWMITILHYAPNLTLLNLILYII 209
Cdd:PRK08676 261 ALLRqsgaaeqfSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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