DNA polymerase, partial [Thalassarchid herpesvirus 1]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| DNA_pol_B super family | cl29029 | DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one ... |
1-79 | 1.34e-23 | ||
DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities. The actual alignment was detected with superfamily member pfam00136: Pssm-ID: 395085 Cd Length: 439 Bit Score: 91.52 E-value: 1.34e-23
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| Name | Accession | Description | Interval | E-value | ||
| DNA_pol_B | pfam00136 | DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one ... |
1-79 | 1.34e-23 | ||
DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities. Pssm-ID: 395085 Cd Length: 439 Bit Score: 91.52 E-value: 1.34e-23
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| POLBc | smart00486 | DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), ... |
1-79 | 4.12e-18 | ||
DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), DNA polymerases in archaea, DNA polymerase II in e. coli, mitochondrial DNA polymerases and and virus DNA polymerases Pssm-ID: 214691 [Multi-domain] Cd Length: 474 Bit Score: 76.42 E-value: 4.12e-18
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| PTZ00166 | PTZ00166 | DNA polymerase delta catalytic subunit; Provisional |
2-79 | 7.24e-17 | ||
DNA polymerase delta catalytic subunit; Provisional Pssm-ID: 240301 [Multi-domain] Cd Length: 1054 Bit Score: 73.14 E-value: 7.24e-17
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| POLBc_delta | cd05533 | DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases ... |
2-79 | 7.31e-17 | ||
DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. Presently, no direct data is available regarding the strand specificity of DNA polymerase during DNA replication in vivo. However, mutation analysis supports the hypothesis that DNA polymerase delta is the enzyme responsible for both elongation and maturation of Okazaki fragments on the lagging strand. Pssm-ID: 99916 Cd Length: 393 Bit Score: 72.68 E-value: 7.31e-17
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| pol2 | TIGR00592 | DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA ... |
2-79 | 4.49e-07 | ||
DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA polymerases.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273159 [Multi-domain] Cd Length: 1172 Bit Score: 45.43 E-value: 4.49e-07
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| PolB | COG0417 | DNA polymerase B elongation subunit [Replication, recombination and repair]; |
17-79 | 1.62e-05 | ||
DNA polymerase B elongation subunit [Replication, recombination and repair]; Pssm-ID: 440186 [Multi-domain] Cd Length: 794 Bit Score: 40.58 E-value: 1.62e-05
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| Name | Accession | Description | Interval | E-value | ||
| DNA_pol_B | pfam00136 | DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one ... |
1-79 | 1.34e-23 | ||
DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities. Pssm-ID: 395085 Cd Length: 439 Bit Score: 91.52 E-value: 1.34e-23
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| POLBc | smart00486 | DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), ... |
1-79 | 4.12e-18 | ||
DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), DNA polymerases in archaea, DNA polymerase II in e. coli, mitochondrial DNA polymerases and and virus DNA polymerases Pssm-ID: 214691 [Multi-domain] Cd Length: 474 Bit Score: 76.42 E-value: 4.12e-18
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| PTZ00166 | PTZ00166 | DNA polymerase delta catalytic subunit; Provisional |
2-79 | 7.24e-17 | ||
DNA polymerase delta catalytic subunit; Provisional Pssm-ID: 240301 [Multi-domain] Cd Length: 1054 Bit Score: 73.14 E-value: 7.24e-17
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| POLBc_delta | cd05533 | DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases ... |
2-79 | 7.31e-17 | ||
DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. Presently, no direct data is available regarding the strand specificity of DNA polymerase during DNA replication in vivo. However, mutation analysis supports the hypothesis that DNA polymerase delta is the enzyme responsible for both elongation and maturation of Okazaki fragments on the lagging strand. Pssm-ID: 99916 Cd Length: 393 Bit Score: 72.68 E-value: 7.31e-17
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| POLBc | cd00145 | DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by ... |
2-79 | 5.62e-08 | ||
DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic (polymerase) and degradative modes (exonucleases) and play roles in the processes of DNA replication, repair, and recombination. DNA-dependent DNA polymerases can be classified in six main groups based upon their phylogenetic relationships with E. coli polymerase I (class A), E. coli polymerase II (class B), E. coli polymerase III (class C), euryarchaeota polymerase II (class D), human polymerase beta (class x), E. coli UmuC/DinB, and eukaryotic RAP 30/Xeroderma pigmentosum variant (class Y). Family B DNA polymerases include E. coli DNA polymerase II, some eubacterial phage DNA polymerases, nuclear replicative DNA polymerases (alpha, delta, epsilon, and zeta), and eukaryotic viral and plasmid-borne enzymes. DNA polymerase is made up of distinct domains and sub-domains. The polymerase domain of DNA polymerase type B (Pol domain) is responsible for the template-directed polymerization of dNTPs onto the growing primer strand of duplex DNA that is usually magnesium dependent. In general, the architecture of the Pol domain has been likened to a right hand with fingers, thumb, and palm sub-domains with a deep groove to accommodate the nucleic acid substrate. There are a few conserved motifs in the Pol domain of family B DNA polymerases. The conserved aspartic acid residues in the DTDS motifs of the palm sub-domain is crucial for binding to divalent metal ion and is suggested to be important for polymerase catalysis. Pssm-ID: 99912 [Multi-domain] Cd Length: 323 Bit Score: 47.75 E-value: 5.62e-08
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| POLBc_zeta | cd05534 | DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member ... |
1-79 | 2.99e-07 | ||
DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production of either spontaneous or induced mutations. Apart from its role in translesion replication, Pol zeta also appears to be involved in somatic hypermutability in B lymphocytes, an important element for the production of high affinity antibodies in response to an antigen. Pssm-ID: 99917 Cd Length: 451 Bit Score: 45.67 E-value: 2.99e-07
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| pol2 | TIGR00592 | DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA ... |
2-79 | 4.49e-07 | ||
DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA polymerases.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair] Pssm-ID: 273159 [Multi-domain] Cd Length: 1172 Bit Score: 45.43 E-value: 4.49e-07
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| PolB | COG0417 | DNA polymerase B elongation subunit [Replication, recombination and repair]; |
17-79 | 1.62e-05 | ||
DNA polymerase B elongation subunit [Replication, recombination and repair]; Pssm-ID: 440186 [Multi-domain] Cd Length: 794 Bit Score: 40.58 E-value: 1.62e-05
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| PRK05762 | PRK05762 | DNA polymerase II; Reviewed |
20-79 | 1.89e-03 | ||
DNA polymerase II; Reviewed Pssm-ID: 235595 [Multi-domain] Cd Length: 786 Bit Score: 34.83 E-value: 1.89e-03
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