9-O-acetyl-N-acetylneuraminic acid deacetylase [Escherichia coli str. K-12 substr. MG1655]
Protein Classification
sialate O-acetylesterase family protein( domain architecture ID 4012)
sialate O-acetylesterase family protein similar to Homo sapiens sialate O-acetylesterase and Escherichia coli 9-O-acetyl-N-acetylneuraminic acid deacetylase
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| SASA super family | cl04187 | Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ... |
11-209 | 3.74e-15 | ||||
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665. The actual alignment was detected with superfamily member pfam03629: Pssm-ID: 427409 Cd Length: 227 Bit Score: 73.39 E-value: 3.74e-15
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| Name | Accession | Description | Interval | E-value | ||||
| SASA | pfam03629 | Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ... |
11-209 | 3.74e-15 | ||||
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665. Pssm-ID: 427409 Cd Length: 227 Bit Score: 73.39 E-value: 3.74e-15
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| KLF1_2_4_N-like | cd22056 | N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of ... |
17-100 | 4.00e-03 | ||||
N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of Kruppel-like factor (KLF)1, KLF2, and KLF4; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specifity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domains of an unknown subfamily of KLFs, predominantly found in fish, related to the N-terminal domains of KLF1, KLF2, and KLF4. Pssm-ID: 409231 [Multi-domain] Cd Length: 339 Bit Score: 38.49 E-value: 4.00e-03
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| Name | Accession | Description | Interval | E-value | ||||
| SASA | pfam03629 | Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this ... |
11-209 | 3.74e-15 | ||||
Carbohydrate esterase, sialic acid-specific acetylesterase; The catalytic triad of this esterase enzyme comprises residues Ser127, His403 and Asp391 in UniProtKB:P70665. Pssm-ID: 427409 Cd Length: 227 Bit Score: 73.39 E-value: 3.74e-15
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| KLF1_2_4_N-like | cd22056 | N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of ... |
17-100 | 4.00e-03 | ||||
N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of Kruppel-like factor (KLF)1, KLF2, and KLF4; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specifity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domains of an unknown subfamily of KLFs, predominantly found in fish, related to the N-terminal domains of KLF1, KLF2, and KLF4. Pssm-ID: 409231 [Multi-domain] Cd Length: 339 Bit Score: 38.49 E-value: 4.00e-03
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| Blast search parameters | ||||
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