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Conserved domains on  [gi|1336409412|gb|AUV48731|]
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DNA-dependent DNA polymerase, partial [Emydoidea herpesvirus 1]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DNA_pol_B super family cl29029
DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one ...
 1-88 1.03e-39

DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities.


The actual alignment was detected with superfamily member pfam00136:

Pssm-ID: 395085  Cd Length: 439  Bit Score: 135.43  E-value: 1.03e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGR 79
Cdd:pfam00136 111 FVKDHVREGLLPKLLKDLLAKRKAIKKLLKEETdPFERAILDKQQLALKITANSVYGFTGFANGRLPCLPIAASVTAIGR 190


                  ....*....
gi 1336409412  80 NMLLATRDY 88
Cdd:pfam00136 191 EMLENTKDL 199
 
Name Accession Description Interval E-value
DNA_pol_B pfam00136
DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one ...
 1-88 1.03e-39

DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities.


Pssm-ID: 395085  Cd Length: 439  Bit Score: 135.43  E-value: 1.03e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGR 79
Cdd:pfam00136 111 FVKDHVREGLLPKLLKDLLAKRKAIKKLLKEETdPFERAILDKQQLALKITANSVYGFTGFANGRLPCLPIAASVTAIGR 190


                  ....*....
gi 1336409412  80 NMLLATRDY 88
Cdd:pfam00136 191 EMLENTKDL 199
POLBc smart00486
DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), ...
 1-88 4.02e-28

DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), DNA polymerases in archaea, DNA polymerase II in e. coli, mitochondrial DNA polymerases and and virus DNA polymerases


Pssm-ID: 214691 [Multi-domain]  Cd Length: 474  Bit Score: 104.92  E-value: 4.02e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412    1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTASPE---EQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTV 77
Cdd:smart00486 357 FVKKNIRKGILPKLLKKLLDKRKEIKKLMKKEKDEseeLKKLLDSRQLALKLTANSVYGYLGFTNSRLPCKPLAASVTAL 436

                           90
                   ....*....|.
gi 1336409412   78 GRNMLLATRDY 88
Cdd:smart00486 437 GREILEKTKEL 447
POLBc_delta cd05533
DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases ...
 1-87 4.82e-27

DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. Presently, no direct data is available regarding the strand specificity of DNA polymerase during DNA replication in vivo. However, mutation analysis supports the hypothesis that DNA polymerase delta is the enzyme responsible for both elongation and maturation of Okazaki fragments on the lagging strand.


Pssm-ID: 99916  Cd Length: 393  Bit Score: 101.19  E-value: 4.82e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGR 79
Cdd:cd05533    66 FVKSSVRKGLLPEILEELLAARKRAKKDLKEETdPFKKAVLDGRQLALKISANSVYGFTGATVGKLPCLEISSSVTSFGR 145


                  ....*...
gi 1336409412  80 NMLLATRD 87
Cdd:cd05533   146 QMIEKTKK 153
PTZ00166 PTZ00166
DNA polymerase delta catalytic subunit; Provisional
 1-87 3.52e-25

DNA polymerase delta catalytic subunit; Provisional


Pssm-ID: 240301 [Multi-domain]  Cd Length: 1054  Bit Score: 97.02  E-value: 3.52e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412    1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTG-VAMGLLPCLEVASTVTTVG 78
Cdd:PTZ00166   603 FVKKEVRKGILPLIVEELIAARKKAKKEMKDEKdPLLKKVLNGRQLALKISANSVYGYTGaQVGGQLPCLEVSTSITSFG 682


                   ....*....
gi 1336409412   79 RNMLLATRD 87
Cdd:PTZ00166   683 RQMIDKTKE 691
pol2 TIGR00592
DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA ...
 4-87 8.45e-12

DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA polymerases.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273159 [Multi-domain]  Cd Length: 1172  Bit Score: 58.91  E-value: 8.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412    4 PHIKQSLLGELLTDWLALRKAIRLRMKT-ASPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNML 82
Cdd:TIGR00592  851 SELEMGILPRELRKLVERRKEVKKLMKQdLNPDLRLQYDIRQKALKLTANSMYGCLGYSKSRFYAKPLAALVTAKGREIL 930


                   ....*
gi 1336409412   83 LATRD 87
Cdd:TIGR00592  931 EHTRQ 935
 
Name Accession Description Interval E-value
DNA_pol_B pfam00136
DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one ...
 1-88 1.03e-39

DNA polymerase family B; This region of DNA polymerase B appears to consist of more than one structural domain, possibly including elongation, DNA-binding and dNTP binding activities.


Pssm-ID: 395085  Cd Length: 439  Bit Score: 135.43  E-value: 1.03e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGR 79
Cdd:pfam00136 111 FVKDHVREGLLPKLLKDLLAKRKAIKKLLKEETdPFERAILDKQQLALKITANSVYGFTGFANGRLPCLPIAASVTAIGR 190


                  ....*....
gi 1336409412  80 NMLLATRDY 88
Cdd:pfam00136 191 EMLENTKDL 199
POLBc smart00486
DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), ...
 1-88 4.02e-28

DNA polymerase type-B family; DNA polymerase alpha, delta, epsilon and zeta chain (eukaryota), DNA polymerases in archaea, DNA polymerase II in e. coli, mitochondrial DNA polymerases and and virus DNA polymerases


Pssm-ID: 214691 [Multi-domain]  Cd Length: 474  Bit Score: 104.92  E-value: 4.02e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412    1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTASPE---EQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTV 77
Cdd:smart00486 357 FVKKNIRKGILPKLLKKLLDKRKEIKKLMKKEKDEseeLKKLLDSRQLALKLTANSVYGYLGFTNSRLPCKPLAASVTAL 436

                           90
                   ....*....|.
gi 1336409412   78 GRNMLLATRDY 88
Cdd:smart00486 437 GREILEKTKEL 447
POLBc_delta cd05533
DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases ...
 1-87 4.82e-27

DNA polymerase type-B delta subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. Presently, no direct data is available regarding the strand specificity of DNA polymerase during DNA replication in vivo. However, mutation analysis supports the hypothesis that DNA polymerase delta is the enzyme responsible for both elongation and maturation of Okazaki fragments on the lagging strand.


Pssm-ID: 99916  Cd Length: 393  Bit Score: 101.19  E-value: 4.82e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGR 79
Cdd:cd05533    66 FVKSSVRKGLLPEILEELLAARKRAKKDLKEETdPFKKAVLDGRQLALKISANSVYGFTGATVGKLPCLEISSSVTSFGR 145


                  ....*...
gi 1336409412  80 NMLLATRD 87
Cdd:cd05533   146 QMIEKTKK 153
PTZ00166 PTZ00166
DNA polymerase delta catalytic subunit; Provisional
 1-87 3.52e-25

DNA polymerase delta catalytic subunit; Provisional


Pssm-ID: 240301 [Multi-domain]  Cd Length: 1054  Bit Score: 97.02  E-value: 3.52e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412    1 YVLPHIKQSLLGELLTDWLALRKAIRLRMKTAS-PEEQLLLDKQQLAIKVTCNSVYGFTG-VAMGLLPCLEVASTVTTVG 78
Cdd:PTZ00166   603 FVKKEVRKGILPLIVEELIAARKKAKKEMKDEKdPLLKKVLNGRQLALKISANSVYGYTGaQVGGQLPCLEVSTSITSFG 682


                   ....*....
gi 1336409412   79 RNMLLATRD 87
Cdd:PTZ00166   683 RQMIDKTKE 691
POLBc cd00145
DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by ...
 4-82 4.35e-15

DNA polymerase type-B family catalytic domain. DNA-directed DNA polymerases elongate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of the growing chain of DNA. DNA-directed DNA polymerases are multifunctional with both synthetic (polymerase) and degradative modes (exonucleases) and play roles in the processes of DNA replication, repair, and recombination. DNA-dependent DNA polymerases can be classified in six main groups based upon their phylogenetic relationships with E. coli polymerase I (class A), E. coli polymerase II (class B), E. coli polymerase III (class C), euryarchaeota polymerase II (class D), human polymerase beta (class x), E. coli UmuC/DinB, and eukaryotic RAP 30/Xeroderma pigmentosum variant (class Y). Family B DNA polymerases include E. coli DNA polymerase II, some eubacterial phage DNA polymerases, nuclear replicative DNA polymerases (alpha, delta, epsilon, and zeta), and eukaryotic viral and plasmid-borne enzymes. DNA polymerase is made up of distinct domains and sub-domains. The polymerase domain of DNA polymerase type B (Pol domain) is responsible for the template-directed polymerization of dNTPs onto the growing primer strand of duplex DNA that is usually magnesium dependent. In general, the architecture of the Pol domain has been likened to a right hand with fingers, thumb, and palm sub-domains with a deep groove to accommodate the nucleic acid substrate. There are a few conserved motifs in the Pol domain of family B DNA polymerases. The conserved aspartic acid residues in the DTDS motifs of the palm sub-domain is crucial for binding to divalent metal ion and is suggested to be important for polymerase catalysis.


Pssm-ID: 99912 [Multi-domain]  Cd Length: 323  Bit Score: 67.78  E-value: 4.35e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   4 PHIKQSLLGELLTDWLALRKAIRLRMKTA--SPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNM 81
Cdd:cd00145    62 PKDRKGLLPRILEELLNFRDEAKKRMKAAklAPEERVLYDNRQQALKVLANSFYGYLGAKFFRFYDPEVAASITSFGREI 141


                  .
gi 1336409412  82 L 82
Cdd:cd00145   142 I 142
POLBc_B3 cd05536
DNA polymerase type-B B3 subfamily catalytic domain. Archaeal proteins that are involved in ...
 4-88 6.23e-13

DNA polymerase type-B B3 subfamily catalytic domain. Archaeal proteins that are involved in DNA replication are similar to those from eukaryotes. Some members of the archaea also possess multiple family B DNA polymerases (B1, B2 and B3). So far there is no specific function(s) has been assigned for different members of the archaea type B DNA polymerases. Phylogenetic analyses of eubacterial, archaeal, and eukaryotic family B DNA polymerases are support independent gene duplications during the evolution of archaeal and eukaryotic family B DNA polymerases. Structural comparison of the thermostable DNA polymerase type B to its mesostable homolog suggests several adaptations to high temperature such as shorter loops, disulfide bridges, and increasing electrostatic interaction at subdomain interfaces.


Pssm-ID: 99919  Cd Length: 371  Bit Score: 61.96  E-value: 6.23e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   4 PHIKQSLLGELLTdwlaLRKAIRLRMKTASPE--EQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNM 81
Cdd:cd05536    66 PGFIPSVLEDLLE----ERRRIKEKMKKLDPEseEYKLLDERQRAIKILANSFYGYMGWANARWYCKECAEAVTAWGREY 141


                  ....*..
gi 1336409412  82 LLATRDY 88
Cdd:cd05536   142 IKTTIKI 148
pol2 TIGR00592
DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA ...
 4-87 8.45e-12

DNA polymerase (pol2); All proteins in this superfamily for which functions are known are DNA polymerases.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273159 [Multi-domain]  Cd Length: 1172  Bit Score: 58.91  E-value: 8.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412    4 PHIKQSLLGELLTDWLALRKAIRLRMKT-ASPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNML 82
Cdd:TIGR00592  851 SELEMGILPRELRKLVERRKEVKKLMKQdLNPDLRLQYDIRQKALKLTANSMYGCLGYSKSRFYAKPLAALVTAKGREIL 930


                   ....*
gi 1336409412   83 LATRD 87
Cdd:TIGR00592  931 EHTRQ 935
POLBc_zeta cd05534
DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member ...
 1-88 2.71e-11

DNA polymerase type-B zeta subfamily catalytic domain. DNA polymerase (Pol) zeta is a member of the eukaryotic B-family of DNA polymerases and distantly related to DNA Pol delta. Pol zeta plays a major role in translesion replication and the production of either spontaneous or induced mutations. Apart from its role in translesion replication, Pol zeta also appears to be involved in somatic hypermutability in B lymphocytes, an important element for the production of high affinity antibodies in response to an antigen.


Pssm-ID: 99917  Cd Length: 451  Bit Score: 57.61  E-value: 2.71e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   1 YVLPHIKQSLLGELLTDWLALRKAIRLRMK--TASPEEQLLLDKQQLAIKVTCNSVYGFTGVAM-GLLPCLEVASTVTTV 77
Cdd:cd05534   121 FVKKSVRKGILPKMLEEILDTRIMVKKAMKkyKDDKKLQRILDARQLALKLLANVTYGYTAASFsGRMPCVEIADSIVQT 200

                          90
                  ....*....|.
gi 1336409412  78 GRNMLLATRDY 88
Cdd:cd05534   201 GRETLERAIEL 211
POLBc_alpha cd05532
DNA polymerase type-B alpha subfamily catalytic domain. Three DNA-dependent DNA polymerases ...
 2-87 4.13e-10

DNA polymerase type-B alpha subfamily catalytic domain. Three DNA-dependent DNA polymerases type B (alpha, delta, and epsilon) have been identified as essential for nuclear DNA replication in eukaryotes. DNA polymerase (Pol) alpha is almost exclusively required for the initiation of DNA replication and the priming of Okazaki fragments during elongation. In most organisms no specific repair role, other than check point control, has been assigned to this enzyme. Pol alpha contains both polymerase and exonuclease domains, but lacks exonuclease activity suggesting that the exonuclease domain may be for structural purposes only.


Pssm-ID: 99915  Cd Length: 400  Bit Score: 54.12  E-value: 4.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   2 VLPHIKQSLLgelltdwlALRKAIRLRMKT-ASPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRN 80
Cdd:cd05532    72 ILPRIIRKLV--------ERRRQVKKLMKSeKDPDKKAQLDIRQLALKLTANSMYGCLGFSYSRFYAKPLAALITSKGRE 143


                  ....*..
gi 1336409412  81 MLLATRD 87
Cdd:cd05532   144 ILQKTKD 150
POLBc_B1 cd05530
DNA polymerase type-B B1 subfamily catalytic domain. Archaeal proteins that are involved in ...
 30-88 2.16e-05

DNA polymerase type-B B1 subfamily catalytic domain. Archaeal proteins that are involved in DNA replication are similar to those from eukaryotes. Some archaeal members also possess multiple family B DNA polymerases (B1, B2 and B3). So far there is no specific function(s) has been assigned for different members of the archaea type B DNA polymerases. Phylogenetic analyses of eubacterial, archaeal, and eukaryotic family B DNA polymerases are support independent gene duplications during the evolution of archaeal and eukaryotic family B DNA polymerases.


Pssm-ID: 99913  Cd Length: 372  Bit Score: 40.80  E-value: 2.16e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1336409412  30 KTASPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNMLLATRDY 88
Cdd:cd05530   101 KSLDEEMRQWYDVVQSAMKVFINASYGVFGAENFPLYCPPVAESTTALGRYIITSTIKK 159
PHA03036 PHA03036
DNA polymerase; Provisional
 14-82 7.16e-05

DNA polymerase; Provisional


Pssm-ID: 222962 [Multi-domain]  Cd Length: 1004  Bit Score: 39.23  E-value: 7.16e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   14 LLTDWLALRKAIRLRMKTASPE-EQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNML 82
Cdd:PHA03036   628 LLKTFLEERARYKKLLKEATSSvEKAIYDSMQYTYKIVANSVYGLMGFRNSALYSYASAKSCTAIGRNMI 697
PRK05762 PRK05762
DNA polymerase II; Reviewed
 4-88 8.51e-05

DNA polymerase II; Reviewed


Pssm-ID: 235595 [Multi-domain]  Cd Length: 786  Bit Score: 39.07  E-value: 8.51e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   4 PHIKQSLLGELLtdwlALRKAIRLRMKTAspeeqllldKQQlAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNMLL 83
Cdd:PRK05762  464 KHFLPEIVERLW----EGRDEAKREMNKP---------LSQ-AIKIIMNAFYGVLGSSGCRFFDPRLASSITMRGHEIMK 529


                  ....*
gi 1336409412  84 ATRDY 88
Cdd:PRK05762  530 QTREL 534
PRK05761 PRK05761
DNA-directed DNA polymerase I;
9-85 9.07e-05

DNA-directed DNA polymerase I;


Pssm-ID: 235594 [Multi-domain]  Cd Length: 787  Bit Score: 38.90  E-value: 9.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1336409412   9 SLLGELLTDwlaLRKAIRLRM---KTASPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNMLLAT 85
Cdd:PRK05761  475 SVLVGLLRD---FRVKIYKKKakdPNLDEERRAWYDVVQRALKVFLNASYGVFGAENFKLYRIEVAESITALGREILLST 551
POLBc_Pol_II_B cd05538
DNA polymerase type-II B subfamily catalytic domain. Bacteria contain five DNA polymerases (I, ...
 9-82 7.48e-03

DNA polymerase type-II B subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as repair of DNA damaged by UV irradiation or oxidation has been proved by genetic studies. DNA polymerase III is the main enzyme responsible for replication of the bacterial chromosome; however, In vivo studies have also shown that Pol II is able to participate in chromosomal DNA replication with larger role in lagging-strand replication.


Pssm-ID: 99921  Cd Length: 347  Bit Score: 33.61  E-value: 7.48e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1336409412   9 SLLGELLTDWLALRKAIRlrmKTASPEEQLLLDKQQLAIKVTCNSVYGFTGVAMGLLPCLEVASTVTTVGRNML 82
Cdd:cd05538    49 ALLKYLVELRLAAKESAR---AAARPAERDAFKAKQAAFKVLINSFYGYLGTGLHAFSDPEAAAEVTRLGRELL 119
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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