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Conserved domains on  [gi|1393630121|gb|AWN85513|]
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PRDM9, partial [Mus musculus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
8-353 1.86e-12

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.18  E-value: 1.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121   8 FSDKSNVNEHQKTHTGEKPYVCRECGRGFTQK--SDLIKHQRTHTGEKPYVCRECGRGFTQKSDLIK------------- 72
Cdd:COG5048    43 FSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlsssssnsndnnl 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121  73 ------------------HQRTHTGEKPY---------------------VCRECGRGFTQKSVLIQHQRTHTGEKPYVC 113
Cdd:COG5048   123 lsshslppssrdpqlpdlLSISNLRNNPLpgnnsssvntpqsnslhpplpANSLSKDPSSNLSLLISSNVSTSIPSSSEN 202
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 114 RECGRgFTAKSNLIQHQRTHTGEKPYVCRECGRGFTAKSVLIQHQRTHTGEKPYVCRECGRGFTQKSDLIKHQRTHTGE- 192
Cdd:COG5048   203 SPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSs 281
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 193 ------KPYVCRECGRGFTAKSNLIQHQRT--HTGE--KPYVCRE--CGRGFTEKSSLIKHQRTHTGEKPYVCRECGRGF 260
Cdd:COG5048   282 sekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSS 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 261 TAKSNL-------IQHQKTHTGEKPYVC--RECGRGFTQKSNLIKHQRTHTGEKPYVCR--ECGRGFTAKSVLIQHQRTH 329
Cdd:COG5048   362 KFSPLLnneppqsLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIH 441
                         410       420
                  ....*....|....*....|....
gi 1393630121 330 TGEKPYVCreCGWGFTQKSDLIQH 353
Cdd:COG5048   442 TNHAPLLC--SILKSFRRDLDLSN 463
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
8-353 1.86e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.18  E-value: 1.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121   8 FSDKSNVNEHQKTHTGEKPYVCRECGRGFTQK--SDLIKHQRTHTGEKPYVCRECGRGFTQKSDLIK------------- 72
Cdd:COG5048    43 FSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlsssssnsndnnl 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121  73 ------------------HQRTHTGEKPY---------------------VCRECGRGFTQKSVLIQHQRTHTGEKPYVC 113
Cdd:COG5048   123 lsshslppssrdpqlpdlLSISNLRNNPLpgnnsssvntpqsnslhpplpANSLSKDPSSNLSLLISSNVSTSIPSSSEN 202
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 114 RECGRgFTAKSNLIQHQRTHTGEKPYVCRECGRGFTAKSVLIQHQRTHTGEKPYVCRECGRGFTQKSDLIKHQRTHTGE- 192
Cdd:COG5048   203 SPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSs 281
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 193 ------KPYVCRECGRGFTAKSNLIQHQRT--HTGE--KPYVCRE--CGRGFTEKSSLIKHQRTHTGEKPYVCRECGRGF 260
Cdd:COG5048   282 sekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSS 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 261 TAKSNL-------IQHQKTHTGEKPYVC--RECGRGFTQKSNLIKHQRTHTGEKPYVCR--ECGRGFTAKSVLIQHQRTH 329
Cdd:COG5048   362 KFSPLLnneppqsLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIH 441
                         410       420
                  ....*....|....*....|....
gi 1393630121 330 TGEKPYVCreCGWGFTQKSDLIQH 353
Cdd:COG5048   442 TNHAPLLC--SILKSFRRDLDLSN 463
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
81-129 4.98e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 35.61  E-value: 4.98e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1393630121  81 KPYvCRECGRGFTQKSVLIQHQRTHTgekpYVCRECGRGFTAKSNLIQH 129
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
265-290 5.48e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.87  E-value: 5.48e-03
                          10        20
                  ....*....|....*....|....*.
gi 1393630121 265 NLIQHQKTHTGEKPYVCRECGRGFTQ 290
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
8-353 1.86e-12

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 68.18  E-value: 1.86e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121   8 FSDKSNVNEHQKTHTGEKPYVCRECGRGFTQK--SDLIKHQRTHTGEKPYVCRECGRGFTQKSDLIK------------- 72
Cdd:COG5048    43 FSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSSlsssssnsndnnl 122
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121  73 ------------------HQRTHTGEKPY---------------------VCRECGRGFTQKSVLIQHQRTHTGEKPYVC 113
Cdd:COG5048   123 lsshslppssrdpqlpdlLSISNLRNNPLpgnnsssvntpqsnslhpplpANSLSKDPSSNLSLLISSNVSTSIPSSSEN 202
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 114 RECGRgFTAKSNLIQHQRTHTGEKPYVCRECGRGFTAKSVLIQHQRTHTGEKPYVCRECGRGFTQKSDLIKHQRTHTGE- 192
Cdd:COG5048   203 SPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLPTASSQSSSPNESDSs 281
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 193 ------KPYVCRECGRGFTAKSNLIQHQRT--HTGE--KPYVCRE--CGRGFTEKSSLIKHQRTHTGEKPYVCRECGRGF 260
Cdd:COG5048   282 sekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSS 361
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 261 TAKSNL-------IQHQKTHTGEKPYVC--RECGRGFTQKSNLIKHQRTHTGEKPYVCR--ECGRGFTAKSVLIQHQRTH 329
Cdd:COG5048   362 KFSPLLnneppqsLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIH 441
                         410       420
                  ....*....|....*....|....
gi 1393630121 330 TGEKPYVCreCGWGFTQKSDLIQH 353
Cdd:COG5048   442 TNHAPLLC--SILKSFRRDLDLSN 463
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
37-358 4.42e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.86  E-value: 4.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121  37 TQKSDLIKHQRTHTGE----KPYVCRECGRGFTQKSDLIKHQRTHTGEKPYVCRECGRGFTQKSV--LIQHQRTHTGEKP 110
Cdd:COG5048    12 NNSVLSSTPKSTLKSLsnapRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPleLSRHLRTHHNNPS 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 111 YVC----------------------------------------------------------------------------- 113
Cdd:COG5048    92 DLNskslplsnskasssslsssssnsndnnllsshslppssrdpqlpdllsisnlrnnplpgnnsssvntpqsnslhppl 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 114 ---RECGRGFTAKSNLIQHQRTHTGEKPYVCRECGRgFTAKSVLIQHQRTHTGEKPYVCRECGRGFTQKSDLIKHQRTHT 190
Cdd:COG5048   172 panSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSS-SYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSS 250
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 191 GEKPYVCRECGRGFTAKSNLIQHQRTHTGE-------KPYVCRECGRGFTEKSSLIKHQRT--HTGE--KPYVCRE--CG 257
Cdd:COG5048   251 SDSSSSASESPRSSLPTASSQSSSPNESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCG 330
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121 258 RGFTAKSNLIQHQKTHTGEKPYVCRECGRGFTQKSNLIK-------HQRTHTGEKPYVC--RECGRGFTAKSVLIQHQRT 328
Cdd:COG5048   331 KLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIIT 410
                         410       420       430
                  ....*....|....*....|....*....|..
gi 1393630121 329 HTGEKPYVCR--ECGWGFTQKSDLIQHQRTHT 358
Cdd:COG5048   411 HLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHT 442
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
3-146 4.52e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.24  E-value: 4.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121   3 QCGQYFSDKSNVNEHQKT--HTGE--KPYVCRE--CGRGFTQKSDLIKHQRTHTGEKPYVCRECGRGFTQKSDLIK---- 72
Cdd:COG5048   294 QCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppq 373
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1393630121  73 ---HQRTHTGEKPYVC--RECGRGFTQKSVLIQHQRTHTGEKPYVCR--ECGRGFTAKSNLIQHQRTHTGEKPYVCRECG 145
Cdd:COG5048   374 slqQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCSILK 453

                  .
gi 1393630121 146 R 146
Cdd:COG5048   454 S 454
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
81-129 4.98e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 35.61  E-value: 4.98e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 1393630121  81 KPYvCRECGRGFTQKSVLIQHQRTHTgekpYVCRECGRGFTAKSNLIQH 129
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
265-290 5.48e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.87  E-value: 5.48e-03
                          10        20
                  ....*....|....*....|....*.
gi 1393630121 265 NLIQHQKTHTGEKPYVCRECGRGFTQ 290
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
279-301 5.85e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 33.81  E-value: 5.85e-03
                          10        20
                  ....*....|....*....|...
gi 1393630121 279 YVCRECGRGFTQKSNLIKHQRTH 301
Cdd:pfam00096   1 YKCPDCGKSFSRKSNLKRHLRTH 23
zf-H2C2_2 pfam13465
Zinc-finger double domain;
125-149 6.23e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.87  E-value: 6.23e-03
                          10        20
                  ....*....|....*....|....*
gi 1393630121 125 NLIQHQRTHTGEKPYVCRECGRGFT 149
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
209-233 6.23e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.87  E-value: 6.23e-03
                          10        20
                  ....*....|....*....|....*
gi 1393630121 209 NLIQHQRTHTGEKPYVCRECGRGFT 233
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
293-317 7.80e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.48  E-value: 7.80e-03
                          10        20
                  ....*....|....*....|....*
gi 1393630121 293 NLIKHQRTHTGEKPYVCRECGRGFT 317
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
154-178 8.87e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.48  E-value: 8.87e-03
                          10        20
                  ....*....|....*....|....*
gi 1393630121 154 LIQHQRTHTGEKPYVCRECGRGFTQ 178
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
41-66 9.22e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.48  E-value: 9.22e-03
                          10        20
                  ....*....|....*....|....*.
gi 1393630121  41 DLIKHQRTHTGEKPYVCRECGRGFTQ 66
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
69-94 9.22e-03

Zinc-finger double domain;


Pssm-ID: 433230 [Multi-domain]  Cd Length: 26  Bit Score: 33.48  E-value: 9.22e-03
                          10        20
                  ....*....|....*....|....*.
gi 1393630121  69 DLIKHQRTHTGEKPYVCRECGRGFTQ 94
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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