|
Name |
Accession |
Description |
Interval |
E-value |
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
65-419 |
1.60e-13 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 73.19 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 65 KAEEASGDKVSASVAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGR--RFMQPVCLRVHLASHAGELPFRC 142
Cdd:COG5048 15 VLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCdkSFSRPLELSRHLRTHHNNPSDLN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 143 TH-CPKAYGTLSKLKIHQRGHTGERPYACPDCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELK------------ 209
Cdd:COG5048 95 SKsLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpplpan 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 210 ----------DLRNHERSHTGERPFLCSECGKSLSR-------------SSSLTCHQRIHA------------------- 247
Cdd:COG5048 175 slskdpssnlSLLISSNVSTSIPSSSENSPLSSSYSipssssdqnlensSSSLPLTTNSQLspksllsqspsslsssdss 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 248 --AQKPYRCPACGKGFTQLSSYQSHERTHSG-EKPFLCPRCGRMFSDPSSFRRHQRAH----EGVKPYRC--EKCGKDFR 318
Cdd:COG5048 255 ssASESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSVnhsgESLKPFSCpySLCGKLFS 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 319 QPADLAMHRRVHTGDRPFKC--LQCDKTFVASWDLKRHALVH-----SGQRPFRCE--ECGRAFAERASLTKHSRMHSGE 389
Cdd:COG5048 335 RNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSF 414
|
410 420 430
....*....|....*....|....*....|..
gi 74214799 390 RP--FHCNACGKSFVVLSSLRKHERTHRSNET 419
Cdd:COG5048 415 RPynCKNPPCSKSFNRHYNLIPHKKIHTNHAP 446
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
248-598 |
2.21e-08 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 57.01 E-value: 2.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 248 AQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGR--MFSDPSSFRRHQRAHEGVKPYRCEKCGKDFRQPADLAM 325
Cdd:COG5048 30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCdkSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 326 HRRVHTGDR----PFKCLQCDKTFVaSWDLKRHALVHSGQRPFRceECGRAFAERA----------------------SL 379
Cdd:COG5048 110 LSSSSSNSNdnnlLSSHSLPPSSRD-PQLPDLLSISNLRNNPLP--GNNSSSVNTPqsnslhpplpanslskdpssnlSL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 380 TKHSRMHSGERPFHCNACGKSFVVLSSLRKHERTHRSNETTGAAPQQELVLGLALPVGVVGEGSaapvagagvgDAPAGL 459
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSS----------SDSSSS 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 460 LGLPPESG----GVVATQWQVVGMTVEhvecqdagvgEAPSTlgdagevggeetdekppQFVCRECKETFSTLTLLRRHE 535
Cdd:COG5048 257 ASESPRSSlptaSSQSSSPNESDSSSE----------KGFSL-----------------PIKSKQCNISFSRSSPLTRHL 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74214799 536 RSH----PELRPFPCT--QCGKSFSDRAGLRKHSRTHSSVRPYSC--SQCPKAFLSASDLRKHERTHPVPI 598
Cdd:COG5048 310 RSVnhsgESLKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQQYKD 380
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
155-178 |
5.23e-04 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 37.74 E-value: 5.23e-04
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
531-554 |
2.42e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.81 E-value: 2.42e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
65-419 |
1.60e-13 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 73.19 E-value: 1.60e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 65 KAEEASGDKVSASVAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGR--RFMQPVCLRVHLASHAGELPFRC 142
Cdd:COG5048 15 VLSSTPKSTLKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCdkSFSRPLELSRHLRTHHNNPSDLN 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 143 TH-CPKAYGTLSKLKIHQRGHTGERPYACPDCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELK------------ 209
Cdd:COG5048 95 SKsLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPqsnslhpplpan 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 210 ----------DLRNHERSHTGERPFLCSECGKSLSR-------------SSSLTCHQRIHA------------------- 247
Cdd:COG5048 175 slskdpssnlSLLISSNVSTSIPSSSENSPLSSSYSipssssdqnlensSSSLPLTTNSQLspksllsqspsslsssdss 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 248 --AQKPYRCPACGKGFTQLSSYQSHERTHSG-EKPFLCPRCGRMFSDPSSFRRHQRAH----EGVKPYRC--EKCGKDFR 318
Cdd:COG5048 255 ssASESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSVnhsgESLKPFSCpySLCGKLFS 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 319 QPADLAMHRRVHTGDRPFKC--LQCDKTFVASWDLKRHALVH-----SGQRPFRCE--ECGRAFAERASLTKHSRMHSGE 389
Cdd:COG5048 335 RNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQqykdlKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSF 414
|
410 420 430
....*....|....*....|....*....|..
gi 74214799 390 RP--FHCNACGKSFVVLSSLRKHERTHRSNET 419
Cdd:COG5048 415 RPynCKNPPCSKSFNRHYNLIPHKKIHTNHAP 446
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
248-598 |
2.21e-08 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 57.01 E-value: 2.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 248 AQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGR--MFSDPSSFRRHQRAHEGVKPYRCEKCGKDFRQPADLAM 325
Cdd:COG5048 30 APRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCdkSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSSS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 326 HRRVHTGDR----PFKCLQCDKTFVaSWDLKRHALVHSGQRPFRceECGRAFAERA----------------------SL 379
Cdd:COG5048 110 LSSSSSNSNdnnlLSSHSLPPSSRD-PQLPDLLSISNLRNNPLP--GNNSSSVNTPqsnslhpplpanslskdpssnlSL 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 380 TKHSRMHSGERPFHCNACGKSFVVLSSLRKHERTHRSNETTGAAPQQELVLGLALPVGVVGEGSaapvagagvgDAPAGL 459
Cdd:COG5048 187 LISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSS----------SDSSSS 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 460 LGLPPESG----GVVATQWQVVGMTVEhvecqdagvgEAPSTlgdagevggeetdekppQFVCRECKETFSTLTLLRRHE 535
Cdd:COG5048 257 ASESPRSSlptaSSQSSSPNESDSSSE----------KGFSL-----------------PIKSKQCNISFSRSSPLTRHL 309
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74214799 536 RSH----PELRPFPCT--QCGKSFSDRAGLRKHSRTHSSVRPYSC--SQCPKAFLSASDLRKHERTHPVPI 598
Cdd:COG5048 310 RSVnhsgESLKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQQYKD 380
|
|
| COG5048 |
COG5048 |
FOG: Zn-finger [General function prediction only]; |
138-299 |
1.00e-07 |
|
FOG: Zn-finger [General function prediction only];
Pssm-ID: 227381 [Multi-domain] Cd Length: 467 Bit Score: 54.70 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 138 LPFRCTHCPKAYGTLSKLKIHQRG--HTGE--RPYACP--DCGKSFADPSVFRKHRRTHAGLRPYSC--ERCGKAYAELK 209
Cdd:COG5048 288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLL 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 210 DLRNHERSH-----TGERPFLC--SECGKSLSRSSSLTCHQRIHAAQKP--YRCPACGKGFTQLSSYQSHERTHSGEKPF 280
Cdd:COG5048 368 NNEPPQSLQqykdlKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPL 447
|
170
....*....|....*....
gi 74214799 281 LCPRCGRMFSDPSSFRRHQ 299
Cdd:COG5048 448 LCSILKSFRRDLDLSNHGK 466
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
192-275 |
1.26e-05 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 47.79 E-value: 1.26e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 192 GLRPYSCE--RCGKAYAELKDLRNHeRSHtgerpflcSECGKSLSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQS 269
Cdd:COG5189 346 DGKPYKCPveGCNKKYKNQNGLKYH-MLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416
|
....*.
gi 74214799 270 HeRTHS 275
Cdd:COG5189 417 H-RKHS 421
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
321-414 |
2.82e-04 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 43.55 E-value: 2.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 321 ADLAMHRRVHTGDRPFKC--LQCDKTFVASWDLKRHALvHSGQRPfrceecgrAFAERASLTKHSRMHSGERPFHCNACG 398
Cdd:COG5189 335 IDTPSRMLKVKDGKPYKCpvEGCNKKYKNQNGLKYHML-HGHQNQ--------KLHENPSPEKMNIFSAKDKPYRCEVCD 405
|
90
....*....|....*.
gi 74214799 399 KSFVVLSSLRKHeRTH 414
Cdd:COG5189 406 KRYKNLNGLKYH-RKH 420
|
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
136-219 |
4.35e-04 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 43.17 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 136 GELPFRC--THCPKAYGTLSKLKIHQR-GHTGERPYACPDcgksfadPSvfrKHRRTHAGLRPYSCERCGKAYAELKDLR 212
Cdd:COG5189 346 DGKPYKCpvEGCNKKYKNQNGLKYHMLhGHQNQKLHENPS-------PE---KMNIFSAKDKPYRCEVCDKRYKNLNGLK 415
|
....*..
gi 74214799 213 NHeRSHT 219
Cdd:COG5189 416 YH-RKHS 421
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
155-178 |
5.23e-04 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 37.74 E-value: 5.23e-04
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
98-121 |
7.82e-04 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 36.97 E-value: 7.82e-04
|
| SFP1 |
COG5189 |
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ... |
249-327 |
1.01e-03 |
|
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];
Pssm-ID: 227516 [Multi-domain] Cd Length: 423 Bit Score: 42.01 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74214799 249 QKPYRCP--ACGKGFTQLSSYQSHeRTHSGEKPFLCPRcgrmfSDPSSfrrHQRAHEGVKPYRCEKCGKDFRQPADLAMH 326
Cdd:COG5189 347 GKPYKCPveGCNKKYKNQNGLKYH-MLHGHQNQKLHEN-----PSPEK---MNIFSAKDKPYRCEVCDKRYKNLNGLKYH 417
|
.
gi 74214799 327 R 327
Cdd:COG5189 418 R 418
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
378-402 |
1.10e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 36.58 E-value: 1.10e-03
10 20
....*....|....*....|....*
gi 74214799 378 SLTKHSRMHSGERPFHCNACGKSFV 402
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFK 25
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
322-346 |
2.19e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.81 E-value: 2.19e-03
10 20
....*....|....*....|....*
gi 74214799 322 DLAMHRRVHTGDRPFKCLQCDKTFV 346
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFK 25
|
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
210-232 |
2.35e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.81 E-value: 2.35e-03
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
531-554 |
2.42e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.81 E-value: 2.42e-03
|
| zf-C2H2 |
pfam00096 |
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ... |
168-190 |
2.61e-03 |
|
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.
Pssm-ID: 395048 [Multi-domain] Cd Length: 23 Bit Score: 35.35 E-value: 2.61e-03
|
| zf-H2C2_2 |
pfam13465 |
Zinc-finger double domain; |
350-374 |
4.63e-03 |
|
Zinc-finger double domain;
Pssm-ID: 463886 [Multi-domain] Cd Length: 26 Bit Score: 35.04 E-value: 4.63e-03
10 20
....*....|....*....|....*
gi 74214799 350 DLKRHALVHSGQRPFRCEECGRAFA 374
Cdd:pfam13465 1 NLKRHMRTHTGEKPYKCPECGKSFK 25
|
|
| zf-C2H2 |
pfam00096 |
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ... |
544-566 |
4.74e-03 |
|
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.
Pssm-ID: 395048 [Multi-domain] Cd Length: 23 Bit Score: 34.97 E-value: 4.74e-03
|
| |
