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Conserved domains on  [gi|612339235|emb|CDN68237|]
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nodC protein, partial [Bradyrhizobium sp. VUPME04]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
nodulat_NodC super family cl37405
chitooligosaccharide synthase NodC; Members of this family are NodC, an ...
 1-246 5.35e-180

chitooligosaccharide synthase NodC; Members of this family are NodC, an N-acetylglucosaminyltransferase involved in the production of nodulation factors through which rhizobia establish symbioses with leguminous plants.


The actual alignment was detected with superfamily member TIGR04242:

Pssm-ID: 275076 [Multi-domain]  Cd Length: 395  Bit Score: 499.65  E-value: 5.35e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    1 RKAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTR 80
Cdd:TIGR04242 120 RKAQIAAIRRSSGDLVLNVDSDTTIAPDVVTKLALKMRDPAVGAAMGQLTASNRRDTWLTRLIDMEYWLACNEERAAQAR 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   81 FGAVMCCCGPCAMYRRSALMLLLDQYETQFFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLR 160
Cdd:TIGR04242 200 FGAVMCCCGPCAMYRRSALLSLLDQYETQLFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDKLGPYLRQQLR 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  161 WARSTYRDTLLGLHLLPGLDRYLTLDVLGQNLGPLLLAISSIAALAQLALTDSVPWWTGLTIVAMTMIRCSVAALRAGEL 240
Cdd:TIGR04242 280 WARSTFRDTLLALRLLPGLDRYLTLDVIGQNLGPLLLALSVLTGLAQLALTATVPWWTILVIAAMTIIRCCVAALRARQL 359


                  ....*.
gi 612339235  241 RFLGFS 246
Cdd:TIGR04242 360 RFLGFS 365
 
Name Accession Description Interval E-value
nodulat_NodC TIGR04242
chitooligosaccharide synthase NodC; Members of this family are NodC, an ...
 1-246 5.35e-180

chitooligosaccharide synthase NodC; Members of this family are NodC, an N-acetylglucosaminyltransferase involved in the production of nodulation factors through which rhizobia establish symbioses with leguminous plants.


Pssm-ID: 275076 [Multi-domain]  Cd Length: 395  Bit Score: 499.65  E-value: 5.35e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    1 RKAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTR 80
Cdd:TIGR04242 120 RKAQIAAIRRSSGDLVLNVDSDTTIAPDVVTKLALKMRDPAVGAAMGQLTASNRRDTWLTRLIDMEYWLACNEERAAQAR 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   81 FGAVMCCCGPCAMYRRSALMLLLDQYETQFFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLR 160
Cdd:TIGR04242 200 FGAVMCCCGPCAMYRRSALLSLLDQYETQLFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDKLGPYLRQQLR 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  161 WARSTYRDTLLGLHLLPGLDRYLTLDVLGQNLGPLLLAISSIAALAQLALTDSVPWWTGLTIVAMTMIRCSVAALRAGEL 240
Cdd:TIGR04242 280 WARSTFRDTLLALRLLPGLDRYLTLDVIGQNLGPLLLALSVLTGLAQLALTATVPWWTILVIAAMTIIRCCVAALRARQL 359


                  ....*.
gi 612339235  241 RFLGFS 246
Cdd:TIGR04242 360 RFLGFS 365
GT2_HAS cd06434
Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are ...
 1-167 8.92e-35

Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are bi-functional glycosyltransferases that catalyze polymerization of hyaluronan. HASs transfer both GlcUA and GlcNAc in beta-(1,3) and beta-(1,4) linkages, respectively to the hyaluronan chain using UDP-GlcNAc and UDP-GlcUA as substrates. HA is made as a free glycan, not attached to a protein or lipid. HASs do not need a primer for HA synthesis; they initiate HA biosynthesis de novo with only UDP-GlcNAc, UDP-GlcUA, and Mg2+. Hyaluronan (HA) is a linear heteropolysaccharide composed of (1-3)-linked beta-D-GlcUA-beta-D-GlcNAc disaccharide repeats. It can be found in vertebrates and a few microbes and is typically on the cell surface or in the extracellular space, but is also found inside mammalian cells. Hyaluronan has several physiochemical and biological functions such as space filling, lubrication, and providing a hydrated matrix through which cells can migrate.


Pssm-ID: 133056 [Multi-domain]  Cd Length: 235  Bit Score: 124.29  E-value: 8.92e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   1 RKAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTR 80
Cdd:cd06434   66 RRALAEGIRHVTTDIVVLLDSDTVWPPNALPEMLKPFEDPKVGGVGTNQRILRPRDSKWSFLAAEYLERRNEEIRAAMSY 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  81 FGAVMCCCGPCAMYRRSALM--LLLDQYETQFFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQ 158
Cdd:cd06434  146 DGGVPCLSGRTAAYRTEILKdfLFLEEFTNETFMGRRLNAGDDRFLTRYVLSHGYKTVYQYTSEAYTETPENYKKFLKQQ 225


                 ....*....
gi 612339235 159 LRWARSTYR 167
Cdd:cd06434  226 LRWSRSNWR 234
Chitin_synth_2 pfam03142
Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They ...
 4-165 1.05e-22

Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).


Pssm-ID: 367353 [Multi-domain]  Cd Length: 527  Bit Score: 96.37  E-value: 1.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    4 QIAAIRRSFGDLVLNVDSDTEIAPDVVSKLV-CKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTRFG 82
Cdd:pfam03142 193 NVTGVSPDFYEYVLMVDADTKVFPDSLTRMVaCMVDDPEIMGLCGETKIANKRQSWVTAIQVFEYYISHHLSKAFESVFG 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   83 AVMCCCGPCAMYRRSALMLLLDQYETQFFRGKPSD-----------------FGEDRHLTILMLKA--GFRTEYVPDAIA 143
Cdd:pfam03142 273 GVTCLPGCFSMYRIKAPKGGDGYWVPILASPDIVEhysenvvdtlhkknlllLGEDRYLTTLMLKTfpKRKTVFVPQAVC 352

                         170       180
                  ....*....|....*....|..
gi 612339235  144 ATVVPDRLLPYLRQQLRWARST 165
Cdd:pfam03142 353 KTIAPDTFKVLLSQRRRWINST 374
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 2-210 5.52e-18

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 80.94  E-value: 5.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   2 KAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAamgqltasnrndswltrlidmeywlacneeraaqtrf 81
Cdd:COG1215  101 AALNAGLKAARGDIVVFLDADTVLDPDWLRRLVAAFADPGVGA------------------------------------- 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  82 gavmccCGPCAMYRRSALMllldqyETQFFRgkPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRW 161
Cdd:COG1215  144 ------SGANLAFRREALE------EVGGFD--EDTLGEDLDLSLRLLRAGYRIVYVPDAVVYEEAPETLRALFRQRRRW 209

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 612339235 162 ARSTYRdtlLGLHLLPGLDRYLTLDVLGQNLGPLLLAISSIAALAQLAL 210
Cdd:COG1215  210 ARGGLQ---LLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLL 255
bcsA PRK11498
cellulose synthase catalytic subunit; Provisional
 88-163 5.41e-03

cellulose synthase catalytic subunit; Provisional


Pssm-ID: 236918 [Multi-domain]  Cd Length: 852  Bit Score: 37.70  E-value: 5.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  88 CGPCAMYRRSALmlllDQ-----YETqffrgkpsdFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRWA 162
Cdd:PRK11498 419 CGSCAVIRRKPL----DEiggiaVET---------VTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWA 485


                 .
gi 612339235 163 R 163
Cdd:PRK11498 486 R 486
 
Name Accession Description Interval E-value
nodulat_NodC TIGR04242
chitooligosaccharide synthase NodC; Members of this family are NodC, an ...
 1-246 5.35e-180

chitooligosaccharide synthase NodC; Members of this family are NodC, an N-acetylglucosaminyltransferase involved in the production of nodulation factors through which rhizobia establish symbioses with leguminous plants.


Pssm-ID: 275076 [Multi-domain]  Cd Length: 395  Bit Score: 499.65  E-value: 5.35e-180
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    1 RKAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTR 80
Cdd:TIGR04242 120 RKAQIAAIRRSSGDLVLNVDSDTTIAPDVVTKLALKMRDPAVGAAMGQLTASNRRDTWLTRLIDMEYWLACNEERAAQAR 199

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   81 FGAVMCCCGPCAMYRRSALMLLLDQYETQFFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLR 160
Cdd:TIGR04242 200 FGAVMCCCGPCAMYRRSALLSLLDQYETQLFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDKLGPYLRQQLR 279

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  161 WARSTYRDTLLGLHLLPGLDRYLTLDVLGQNLGPLLLAISSIAALAQLALTDSVPWWTGLTIVAMTMIRCSVAALRAGEL 240
Cdd:TIGR04242 280 WARSTFRDTLLALRLLPGLDRYLTLDVIGQNLGPLLLALSVLTGLAQLALTATVPWWTILVIAAMTIIRCCVAALRARQL 359


                  ....*.
gi 612339235  241 RFLGFS 246
Cdd:TIGR04242 360 RFLGFS 365
GT2_HAS cd06434
Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are ...
 1-167 8.92e-35

Hyaluronan synthases catalyze polymerization of hyaluronan; Hyaluronan synthases (HASs) are bi-functional glycosyltransferases that catalyze polymerization of hyaluronan. HASs transfer both GlcUA and GlcNAc in beta-(1,3) and beta-(1,4) linkages, respectively to the hyaluronan chain using UDP-GlcNAc and UDP-GlcUA as substrates. HA is made as a free glycan, not attached to a protein or lipid. HASs do not need a primer for HA synthesis; they initiate HA biosynthesis de novo with only UDP-GlcNAc, UDP-GlcUA, and Mg2+. Hyaluronan (HA) is a linear heteropolysaccharide composed of (1-3)-linked beta-D-GlcUA-beta-D-GlcNAc disaccharide repeats. It can be found in vertebrates and a few microbes and is typically on the cell surface or in the extracellular space, but is also found inside mammalian cells. Hyaluronan has several physiochemical and biological functions such as space filling, lubrication, and providing a hydrated matrix through which cells can migrate.


Pssm-ID: 133056 [Multi-domain]  Cd Length: 235  Bit Score: 124.29  E-value: 8.92e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   1 RKAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTR 80
Cdd:cd06434   66 RRALAEGIRHVTTDIVVLLDSDTVWPPNALPEMLKPFEDPKVGGVGTNQRILRPRDSKWSFLAAEYLERRNEEIRAAMSY 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  81 FGAVMCCCGPCAMYRRSALM--LLLDQYETQFFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQ 158
Cdd:cd06434  146 DGGVPCLSGRTAAYRTEILKdfLFLEEFTNETFMGRRLNAGDDRFLTRYVLSHGYKTVYQYTSEAYTETPENYKKFLKQQ 225


                 ....*....
gi 612339235 159 LRWARSTYR 167
Cdd:cd06434  226 LRWSRSNWR 234
CESA_like cd06423
CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily ...
 1-100 2.54e-30

CESA_like is the cellulose synthase superfamily; The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of Glucan.


Pssm-ID: 133045 [Multi-domain]  Cd Length: 180  Bit Score: 111.16  E-value: 2.54e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   1 RKAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCK-MQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQT 79
Cdd:cd06423   67 AGALNAGLRHAKGDIVVVLDADTILEPDALKRLVVPfFADPKVGAVQGRVRVRNGSENLLTRLQAIEYLSIFRLGRRAQS 146

                         90       100
                 ....*....|....*....|.
gi 612339235  80 RFGAVMCCCGPCAMYRRSALM 100
Cdd:cd06423  147 ALGGVLVLSGAFGAFRREALR 167
Chitin_synth_C cd04190
C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate ...
 16-166 9.20e-25

C-terminal domain of Chitin Synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin; Chitin synthase, also called UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase, catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of GlcNAc residues formed by covalent beta-1,4 linkages. Chitin is an important component of the cell wall of fungi and bacteria and it is synthesized on the cytoplasmic surface of the cell membrane by membrane bound chitin synthases. Studies with fungi have revealed that most of them contain more than one chitin synthase gene. At least five subclasses of chitin synthases have been identified.


Pssm-ID: 133033 [Multi-domain]  Cd Length: 244  Bit Score: 98.15  E-value: 9.20e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  16 VLNVDSDTEIAPDVVSKLVCKM-QDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTRFGAVMCCCGPCAMY 94
Cdd:cd04190   77 ILLVDADTKFDPDSIVQLYKAMdKDPEIGGVCGEIHPMGKKQGPLVMYQVFEYAISHWLDKAFESVFGFVTCLPGCFSMY 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  95 RRSALMLLLDQY----ETQFFRGKPS--------DFGEDRHLTILMLKAGFRTE--YVPDAIAATVVPDRLLPYLRQQLR 160
Cdd:cd04190  157 RIEALKGDNGGKgpllDYAYLTNTVDslhkknnlDLGEDRILCTLLLKAGPKRKylYVPGAVAETDVPETFVELLSQRRR 236


                 ....*.
gi 612339235 161 WARSTY 166
Cdd:cd04190  237 WINSTI 242
Chitin_synth_2 pfam03142
Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They ...
 4-165 1.05e-22

Chitin synthase; Members of this family are fungal chitin synthase EC:2.4.1.16 enzymes. They catalyze chitin synthesis as follows: UDP-N-acetyl-D-glucosamine + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N) <=> UDP + {(1,4)-(N-acetyl-beta-D-glucosaminyl)}(N+1).


Pssm-ID: 367353 [Multi-domain]  Cd Length: 527  Bit Score: 96.37  E-value: 1.05e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    4 QIAAIRRSFGDLVLNVDSDTEIAPDVVSKLV-CKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTRFG 82
Cdd:pfam03142 193 NVTGVSPDFYEYVLMVDADTKVFPDSLTRMVaCMVDDPEIMGLCGETKIANKRQSWVTAIQVFEYYISHHLSKAFESVFG 272

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   83 AVMCCCGPCAMYRRSALMLLLDQYETQFFRGKPSD-----------------FGEDRHLTILMLKA--GFRTEYVPDAIA 143
Cdd:pfam03142 273 GVTCLPGCFSMYRIKAPKGGDGYWVPILASPDIVEhysenvvdtlhkknlllLGEDRYLTTLMLKTfpKRKTVFVPQAVC 352

                         170       180
                  ....*....|....*....|..
gi 612339235  144 ATVVPDRLLPYLRQQLRWARST 165
Cdd:pfam03142 353 KTIAPDTFKVLLSQRRRWINST 374
BcsA COG1215
Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1, ...
 2-210 5.52e-18

Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility];


Pssm-ID: 440828 [Multi-domain]  Cd Length: 303  Bit Score: 80.94  E-value: 5.52e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   2 KAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAamgqltasnrndswltrlidmeywlacneeraaqtrf 81
Cdd:COG1215  101 AALNAGLKAARGDIVVFLDADTVLDPDWLRRLVAAFADPGVGA------------------------------------- 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  82 gavmccCGPCAMYRRSALMllldqyETQFFRgkPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRW 161
Cdd:COG1215  144 ------SGANLAFRREALE------EVGGFD--EDTLGEDLDLSLRLLRAGYRIVYVPDAVVYEEAPETLRALFRQRRRW 209

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 612339235 162 ARSTYRdtlLGLHLLPGLDRYLTLDVLGQNLGPLLLAISSIAALAQLAL 210
Cdd:COG1215  210 ARGGLQ---LLLKHRPLLRPRRLLLFLLLLLLPLLLLLLLLALLALLLL 255
CESA_CelA_like cd06421
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of ...
 6-167 5.42e-15

CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.


Pssm-ID: 133043 [Multi-domain]  Cd Length: 234  Bit Score: 71.83  E-value: 5.42e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   6 AAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQD-PAVG-AAMGQLTASNRNDSWLTR--LIDMEYWLACNEERAaqTRF 81
Cdd:cd06421   78 NALAHTTGDFVAILDADHVPTPDFLRRTLGYFLDdPKVAlVQTPQFFYNPDPFDWLADgaPNEQELFYGVIQPGR--DRW 155

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  82 GAVMCCcGPCAMYRRSALMLLldqyetqffRGKPSD-FGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLR 160
Cdd:cd06421  156 GAAFCC-GSGAVVRREALDEI---------GGFPTDsVTEDLATSLRLHAKGWRSVYVPEPLAAGLAPETLAAYIKQRLR 225


                 ....*..
gi 612339235 161 WARSTYR 167
Cdd:cd06421  226 WARGMLQ 232
Glycos_transf_2 pfam00535
Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, ...
 2-99 4.27e-13

Glycosyl transferase family 2; Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.


Pssm-ID: 425738 [Multi-domain]  Cd Length: 166  Bit Score: 65.11  E-value: 4.27e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    2 KAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMeYWLACNEERAAQTRF 81
Cdd:pfam00535  68 GARNAGLRAATGDYIAFLDADDEVPPDWLEKLVEALEEDGADVVVGSRYVIFGETGEYRRASRI-TLSRLPFFLGLRLLG 146

                          90
                  ....*....|....*...
gi 612339235   82 GAVMCCCGPCAMYRRSAL 99
Cdd:pfam00535 147 LNLPFLIGGFALYRREAL 164
Glyco_tranf_2_3 pfam13641
Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include ...
 7-164 7.27e-13

Glycosyltransferase like family 2; Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433372 [Multi-domain]  Cd Length: 230  Bit Score: 65.86  E-value: 7.27e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    7 AIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRnDSWLTRLIDMEYWLAcNEERAAQTRFGAVMC 86
Cdd:pfam13641  82 GFRAVKSDLVVLHDDDSVLHPGTLKKYVQYFDSPKVGAVGTPVFSLNR-STMLSALGALEFALR-HLRMMSLRLALGVLP 159

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 612339235   87 CCGPCAMYRRSalmlLLDQYETqfFRGKPSdFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRWARS 164
Cdd:pfam13641 160 LSGAGSAIRRE----VLKELGL--FDPFFL-LGDDKSLGRRLRRHGWRVAYAPDAAVRTVFPTYLAASIKQRARWVYG 230
Glyco_trans_2_3 pfam13632
Glycosyl transferase family group 2; Members of this family of prokaryotic proteins include ...
 15-163 1.28e-11

Glycosyl transferase family group 2; Members of this family of prokaryotic proteins include putative glucosyltransferases, which are involved in bacterial capsule biosynthesis.


Pssm-ID: 433365 [Multi-domain]  Cd Length: 192  Bit Score: 61.58  E-value: 1.28e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   15 LVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNdSWLTRLIDMEYWLACNEERAAQTRFGAVMCCCGPCAMY 94
Cdd:pfam13632   1 WILLLDADTVLPPDCLLGIANEMASPEVAIIQGPILPMNVG-NYLEELAALFFADDHGKSIPVRMALGRVLPFVGSGAFL 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 612339235   95 RRSALmllldqYETQFFRgkPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRWAR 163
Cdd:pfam13632  80 RRSAL------QEVGGWD--DGSVSEDFDFGLRLQRAGYRVRFAPYSAVYEKSPLTFRDFLRQRRRWAY 140
CESA_like_1 cd06439
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of ...
 2-160 1.14e-10

CESA_like_1 is a member of the cellulose synthase (CESA) superfamily; This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.


Pssm-ID: 133061 [Multi-domain]  Cd Length: 251  Bit Score: 59.90  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   2 KAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSwltrlIDME--YWLACNEERAAQT 79
Cdd:cd06439   99 AALNRALALATGEIVVFTDANALLDPDALRLLVRHFADPSVGAVSGELVIVDGGGS-----GSGEglYWKYENWLKRAES 173

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  80 RFGAVMCCCGPCAMYRRSAlmllldqyetqfFRGKPSDFG-EDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQ 158
Cdd:cd06439  174 RLGSTVGANGAIYAIRREL------------FRPLPADTInDDFVLPLRIARQGYRVVYEPDAVAYEEVAEDGSEEFRRR 241


                 ..
gi 612339235 159 LR 160
Cdd:cd06439  242 VR 243
CESA_NdvC_like cd06435
NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase; ...
 7-162 1.06e-06

NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase; NdvC_like proteins in this family are putative bacterial beta-(1,6)-glucosyltransferase. Bradyrhizobium japonicum synthesizes periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans during growth under hypoosmotic conditions. Two genes (ndvB, ndvC) are involved in the beta-(1, 3), beta-(1,6)-glucan synthesis. The ndvC mutant strain resulted in synthesis of altered cyclic beta-glucans composed almost entirely of beta-(1, 3)-glycosyl linkages. The periplasmic cyclic beta-(1,3),beta-(1,6)-D-glucans function for osmoregulation. The ndvC mutation also affects the ability of the bacteria to establish a successful symbiotic interaction with host plant. Thus, the beta-glucans may function as suppressors of a host defense response.


Pssm-ID: 133057 [Multi-domain]  Cd Length: 236  Bit Score: 48.17  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   7 AIRRSFGD--LVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWL-------ACNEERAA 77
Cdd:cd06435   77 ALERTAPDaeIIAVIDADYQVEPDWLKRLVPIFDDPRVGFVQAPQDYRDGEESLFKRMCYAEYKGffdigmvSRNERNAI 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  78 QTRfgAVMCccgpcaMYRRSALmlllDQYetqffrGKPSDFG--EDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYL 155
Cdd:cd06435  157 IQH--GTMC------LIRRSAL----DDV------GGWDEWCitEDSELGLRMHEAGYIGVYVAQSYGHGLIPDTFEAFK 218


                 ....*..
gi 612339235 156 RQQLRWA 162
Cdd:cd06435  219 KQRFRWA 225
Glyco_transf_21 pfam13506
Glycosyl transferase family 21; This is a family of ceramide beta-glucosyltransferases - EC:2. ...
 3-163 5.10e-06

Glycosyl transferase family 21; This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80.


Pssm-ID: 433264 [Multi-domain]  Cd Length: 173  Bit Score: 45.35  E-value: 5.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235    3 AQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLAcneeRAAQTRFG 82
Cdd:pfam13506  21 NLLQGLEAAKYDLLVISDSDIRVPPDYLRDLLAPLADPKVGLVTSPPVGSDPKGLAAALEAAFFNTLA----GVLQAALS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   83 AVMCCCGPCAMYRRSALmlllDQYETqfFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDR--LLPYLRQQLR 160
Cdd:pfam13506  97 GIGFAVGMSMAFRRADL----ERIGG--FEALADYLAEDYALGKLLRAAGLKVVLSPRPILQTSGPRRtsFRAFMARQLR 170


                  ...
gi 612339235  161 WAR 163
Cdd:pfam13506 171 WAR 173
Glucosylceramide_synthase cd02520
Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid ...
 13-165 2.16e-05

Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment.


Pssm-ID: 133012 [Multi-domain]  Cd Length: 196  Bit Score: 44.13  E-value: 2.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  13 GDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGqltasnrndswltrlidmeywlacneeraaqtrfgavMCCCGPCA 92
Cdd:cd02520   87 YDILVISDSDISVPPDYLRRMVAPLMDPGVGLVTC-------------------------------------LCAFGKSM 129

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 612339235  93 MYRRSALmlllDQYETqfFRGKPSDFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRWARST 165
Cdd:cd02520  130 ALRREVL----DAIGG--FEAFADYLAEDYFLGKLIWRLGYRVVLSPYVVMQPLGSTSLASFWRRQLRWSRTR 196
Succinoglycan_BP_ExoA cd02525
ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA ...
 7-167 1.58e-04

ExoA is involved in the biosynthesis of succinoglycan; Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.


Pssm-ID: 133016 [Multi-domain]  Cd Length: 249  Bit Score: 41.83  E-value: 1.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   7 AIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWltrlidmeywlaCNEERAAQTRFG---- 82
Cdd:cd02525   76 GIRNSRGDIIIRVDAHAVYPKDYILELVEALKRTGADNVGGPMETIGESKFQ------------KAIAVAQSSPLGsggs 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  83 -----AVMCCC---GPCAMYRRSALmlllDQ---YETQFFRGkpsdfgEDRHLTILMLKAGFRTEYVPDAIAATVVPDRL 151
Cdd:cd02525  144 ayrggAVKIGYvdtVHHGAYRREVF----EKvggFDESLVRN------EDAELNYRLRKAGYKIWLSPDIRVYYYPRSTL 213

                        170
                 ....*....|....*.
gi 612339235 152 LPYLRQQLRWARSTYR 167
Cdd:cd02525  214 KKLARQYFRYGKWRAR 229
GlcNAc-1-P_transferase cd06436
N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1, ...
 15-102 2.34e-04

N-acetyl-glucosamine transferase is involved in the synthesis of Poly-beta-1,6-N-acetyl-D-glucosamine; N-acetyl-glucosamine transferase is responsible for the synthesis of bacteria Poly-beta-1,6-N-acetyl-D-glucosamine (PGA). Poly-beta-1,6-N-acetyl-D-glucosamine is a homopolymer that serves as an adhesion for the maintenance of biofilm structural stability in diverse eubacteria. N-acetyl-glucosamine transferase is the product of gene pgaC. Genetic analysis indicated that all four genes of the pgaABCD locus were required for the PGA production, pgaC being a glycosyltransferase.


Pssm-ID: 133058 [Multi-domain]  Cd Length: 191  Bit Score: 40.83  E-value: 2.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  15 LVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWLACNEERAAQTRFGAV-MCCCGPCAm 93
Cdd:cd06436   92 IIAVIDADGRLDPNALEAVAPYFSDPRVAGTQSRVRMYNRHKNLLTILQDLEFFIIIAATQSLRALTGTVgLGGNGQFM- 170


                 ....*....
gi 612339235  94 yRRSALMLL 102
Cdd:cd06436  171 -RLSALDGL 178
WcaA COG0463
Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis]; ...
 2-139 2.38e-04

Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440231 [Multi-domain]  Cd Length: 208  Bit Score: 40.84  E-value: 2.38e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235   2 KAQIAAIRRSFGDLVLNVDSDTEIAPDVVSKLVCKMQDPAVGAAMGQLTASNRNDSWLTRLIDMEYWlacneeraAQTRF 81
Cdd:COG0463   72 AARNAGLAAARGDYIAFLDADDQLDPEKLEELVAALEEGPADLVYGSRLIREGESDLRRLGSRLFNL--------VRLLT 143

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 612339235  82 GAVMCCCGpCAMYRRSALMLLldqyetqffrGKPSDFGEDRHLtILMLKAGFRTEYVP 139
Cdd:COG0463  144 NLPDSTSG-FRLFRREVLEEL----------GFDEGFLEDTEL-LRALRHGFRIAEVP 189
bcsA PRK11498
cellulose synthase catalytic subunit; Provisional
 88-163 5.41e-03

cellulose synthase catalytic subunit; Provisional


Pssm-ID: 236918 [Multi-domain]  Cd Length: 852  Bit Score: 37.70  E-value: 5.41e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 612339235  88 CGPCAMYRRSALmlllDQ-----YETqffrgkpsdFGEDRHLTILMLKAGFRTEYVPDAIAATVVPDRLLPYLRQQLRWA 162
Cdd:PRK11498 419 CGSCAVIRRKPL----DEiggiaVET---------VTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWA 485


                 .
gi 612339235 163 R 163
Cdd:PRK11498 486 R 486
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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