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Conserved domains on  [gi|641957197|emb|CDR01139|]
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unnamed protein product, partial [Oncorhynchus mykiss]

Protein Classification

ABC transporter A family member( domain architecture ID 10126116)

ABC transporter A family member (ABCA) may mediate the transport of a variety of lipid compounds; contains the ATP-binding and transmembrane (TM) components of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter

CATH:  3.40.50.300
Gene Ontology:  GO:0140359|GO:0042626|GO:0005524|GO:0016887
PubMed:  18535149|16540294|24638992|25750732
SCOP:  4003976
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 45-268 2.36e-125

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


:

Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 355.66  E-value: 2.36e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:cd03263    1 LQIRNLTKTYKK---GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03263   78 GYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDIlKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLK 268
Cdd:cd03263  158 DEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
 
Name Accession Description Interval E-value
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 45-268 2.36e-125

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 355.66  E-value: 2.36e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:cd03263    1 LQIRNLTKTYKK---GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03263   78 GYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDIlKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLK 268
Cdd:cd03263  158 DEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 17-270 1.29e-119

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 376.66  E-value: 1.29e-119
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    17 SSQPIEDDDEDVASERRRVLRGEADNDMLKIDNLTKVYKSRKMGrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLT 96
Cdd:TIGR01257 1910 AKEPIFDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSP---AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLT 1986

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    97 GDESTTGGEAFIGGSSILKELLRVQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADM 176
Cdd:TIGR01257 1987 GDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADR 2066

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   177 PAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNG 256
Cdd:TIGR01257 2067 LAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146

                          250
                   ....*....|....
gi 641957197   257 RFKCLGSIQHLKNR 270
Cdd:TIGR01257 2147 AFQCLGTIQHLKSK 2160
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
45-270 5.28e-89

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 263.85  E-value: 5.28e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:COG1131    1 IEVRGLTKRY-----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:COG1131   76 GYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLIL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:COG1131  156 DEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
45-257 1.00e-52

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 173.84  E-value: 1.00e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:PRK13537   8 IDFRNVEKRY-----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:PRK13537  83 GVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK13537 163 DEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGR 215
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 65-209 1.12e-32

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 116.98  E-value: 1.12e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   65 VDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQSIGYCPQFDALFEDLTAREHL 143
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKsLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  144 ELYTRLRGIPWKDEERVVSWALEKLELSKYAD----MPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTT 209
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
48-257 8.15e-31

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 121.00  E-value: 8.15e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  48 DNLTkvyksRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGYC 127
Cdd:NF033858 270 RGLT-----MRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDIATRRRVGYM 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 128 PQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEP 207
Cdd:NF033858 345 SQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEP 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 641957197 208 TTGMDPKARRFLWNLILDiL--KTGRSVVLTSHSMEECEaLCTRLGIMVNGR 257
Cdd:NF033858 425 TSGVDPVARDMFWRLLIE-LsrEDGVTIFISTHFMNEAE-RCDRISLMHAGR 474
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
57-270 9.56e-27

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 106.74  E-value: 9.56e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  57 RKMGRILAVDRLCLGVRPGECFGLLGVNGAG--KTTTFKMLTGDESTTGGEAFIGGSSILKELLRvqqSIG-YCPQFDAL 133
Cdd:NF000106  21 KHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*GPDAGRRPWRF*TWCANRRALRR---TIG*HRPVR*GR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 FEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDP 213
Cdd:NF000106  98 RESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDP 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 214 KARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:NF000106 178 RTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
64-242 2.81e-20

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 85.75  E-value: 2.81e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSilkellrvqqSIGYCPQFDALFEDL--TARE 141
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGA----------RVAYVPQRSEVPDSLplTVRD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLELYTRLRGIPW----KDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARR 217
Cdd:NF040873  77 LVAMGRWARRGLWrrltRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRE 156

                        170       180
                 ....*....|....*....|....*
gi 641957197 218 FLWNLILDILKTGRSVVLTSHSMEE 242
Cdd:NF040873 157 RIIALLAEEHARGATVVVVTHDLEL 181
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
60-244 3.23e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 84.02  E-value: 3.23e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  60 GRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR--VQQSIGYCPQF--DALFE 135
Cdd:NF033858  12 GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRraVCPRIAYMPQGlgKNLYP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 136 DLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKA 215
Cdd:NF033858  92 TLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLS 171

                        170       180       190
                 ....*....|....*....|....*....|.
gi 641957197 216 RRFLWNLILDILKT--GRSVVLTSHSMEECE 244
Cdd:NF033858 172 RRQFWELIDRIRAErpGMSVLVATAYMEEAE 202
GguA NF040905
sugar ABC transporter ATP-binding protein;
175-258 1.21e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.94  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 175 DMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMV 254
Cdd:NF040905 399 FQKVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVMN 478


                 ....
gi 641957197 255 NGRF 258
Cdd:NF040905 479 EGRI 482
 
Name Accession Description Interval E-value
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
 45-268 2.36e-125

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 355.66  E-value: 2.36e-125
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:cd03263    1 LQIRNLTKTYKK---GTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRTDRKAARQSL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03263   78 GYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDIlKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLK 268
Cdd:cd03263  158 DEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIGSPQELK 220
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 17-270 1.29e-119

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 376.66  E-value: 1.29e-119
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    17 SSQPIEDDDEDVASERRRVLRGEADNDMLKIDNLTKVYKSRKMGrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLT 96
Cdd:TIGR01257 1910 AKEPIFDEDDDVAEERQRIISGGNKTDILRLNELTKVYSGTSSP---AVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLT 1986

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    97 GDESTTGGEAFIGGSSILKELLRVQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADM 176
Cdd:TIGR01257 1987 GDTTVTSGDATVAGKSILTNISDVHQNMGYCPQFDAIDDLLTGREHLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADR 2066

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   177 PAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNG 256
Cdd:TIGR01257 2067 LAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSMEECEALCTRLAIMVKG 2146

                          250
                   ....*....|....
gi 641957197   257 RFKCLGSIQHLKNR 270
Cdd:TIGR01257 2147 AFQCLGTIQHLKSK 2160
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
45-270 5.28e-89

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 263.85  E-value: 5.28e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:COG1131    1 IEVRGLTKRY-----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAEVRRRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:COG1131   76 GYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLIL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:COG1131  156 DEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDELKAR 221
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
 57-270 8.93e-70

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 217.26  E-value: 8.93e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   57 RKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGYCPQFDALFED 136
Cdd:TIGR01188   1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGYDVVREPRKVRRSIGIVPQYASVDED 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  137 LTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKAR 216
Cdd:TIGR01188  81 LTGRENLEMMGRLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGLDPRTR 160

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 641957197  217 RFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:TIGR01188 161 RAIWDYIRALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIAEGTPEELKRR 214
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
 47-268 2.35e-69

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 213.39  E-value: 2.35e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGY 126
Cdd:cd03265    3 VENLVKKY-----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVVREPREVRRRIGI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 127 CPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDE 206
Cdd:cd03265   78 VFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDE 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 207 PTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLK 268
Cdd:cd03265  158 PTIGLDPQTRAHVWEYIEKLKEEfGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEELK 220
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
 45-258 3.77e-68

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 208.79  E-value: 3.77e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:cd03230    1 IEVRNLSKRYGKKT-----ALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEVKRRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLElytrlrgipwkdeervvswaleklelskyadmpagtYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03230   76 GYLPEEPSLYENLTVRENLK------------------------------------LSGGMKQRLALAQALLHDPELLIL 119

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:cd03230  120 DEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
 44-270 1.59e-63

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 199.31  E-value: 1.59e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQS 123
Cdd:COG4555    1 MIEVENLSKKYGKVP-----ALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPREARRQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:COG4555   76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:COG4555  156 LDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREE 222
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
45-257 1.00e-52

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 173.84  E-value: 1.00e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:PRK13537   8 IDFRNVEKRY-----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRARHARQRV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:PRK13537  83 GVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVL 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK13537 163 DEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGR 215
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
 45-257 1.37e-51

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 167.78  E-value: 1.37e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQsI 124
Cdd:cd03268    1 LKTNDLTKTYGKKR-----VLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEALRR-I 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVvswaLEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03268   75 GALIEAPGFYPNLTARENLRLLARLLGIRKKRIDEV----LDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLIL 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03268  151 DEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGK 203
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 44-270 9.17e-51

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 168.36  E-value: 9.17e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKEllrVQQS 123
Cdd:COG4152    1 MLELKGLTKRFGDKT-----AVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPE---DRRR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKD-EERVVSWaLEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLV 202
Cdd:COG4152   73 IGYLPEERGLYPKMKVGEQLVYLARLKGLSKAEaKRRADEW-LERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELL 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 203 FLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:COG4152  152 ILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVDEIRRQ 219
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
 44-257 1.82e-50

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 165.23  E-value: 1.82e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQS 123
Cdd:cd03266    1 MITADALTKRFRDVK-KTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEPAEARRR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:cd03266   80 LGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03266  160 LDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGR 213
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
 45-259 2.02e-50

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 164.67  E-value: 2.02e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGeCFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:cd03264    1 LQLENLTKRYGKKR-----ALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQKLRRRI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03264   75 GYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIV 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 205 DEPTTGMDPKAR-RFLwNLILDiLKTGRSVVLTSHSMEECEALCTRLGIMVNGRFK 259
Cdd:cd03264  155 DEPTAGLDPEERiRFR-NLLSE-LGEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
 44-238 8.54e-49

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 160.34  E-value: 8.54e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQS 123
Cdd:COG4133    2 MLEAENLSCRR-----GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDAREDYRRR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWkDEERVVSwALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:COG4133   77 LAYLGHADGLKPELTVRENLRFWAALYGLRA-DREAIDE-ALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:COG4133  155 LDEPFTALDAAGVALLAELIAAHLARGGAVLLTTH 189
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
 45-257 1.30e-48

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 160.14  E-value: 1.30e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKEllrVQQSI 124
Cdd:cd03269    1 LEVENVTKRF-----GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIA---ARNRI 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03269   73 GYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLIL 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03269  153 DEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGR 205
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
 47-269 2.72e-48

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 171.73  E-value: 2.72e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    47 IDNLTKVYKSrkMGRIlAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGY 126
Cdd:TIGR01257  931 VKNLVKIFEP--SGRP-AVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIETNLDAVRQSLGM 1007

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   127 CPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDE 206
Cdd:TIGR01257 1008 CPQHNILFHHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDE 1087

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197   207 PTTGMDPKARRFLWNLILDiLKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:TIGR01257 1088 PTSGVDPYSRRSIWDLLLK-YRSGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSGTPLFLKN 1149
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
44-257 4.10e-48

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 162.69  E-value: 4.10e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDnLTKVYKSrkMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQS 123
Cdd:PRK13536  39 TVAID-LAGVSKS--YGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLARAR 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:PRK13536 116 IGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLI 195

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK13536 196 LDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGR 249
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
 45-257 3.01e-42

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 144.50  E-value: 3.01e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQQ 122
Cdd:cd03219    1 LEVRGLTKRF-----GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDItgLPPHEIARL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLEL-------YTRLRGIPWKDEERVVSWA---LEKLELSKYADMPAGTYSGGNKRKLSTA 192
Cdd:cd03219   76 GIGRTFQIPRLFPELTVLENVMVaaqartgSGLLLARARREEREARERAeelLERVGLADLADRPAGELSYGQQRRLEIA 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 193 IALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03219  156 RALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGR 220
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
 45-257 6.12e-41

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 141.14  E-value: 6.12e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELL--RVQQ 122
Cdd:cd03218    1 LRAENLSKRYGKRK-----VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPMhkRARL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLV 202
Cdd:cd03218   76 GIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKFL 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 203 FLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03218  156 LLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGK 210
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
 45-257 2.18e-40

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 138.81  E-value: 2.18e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRvQQSI 124
Cdd:cd03259    1 LELKGLSKTY-----GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE-RRNI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03259   75 GMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLL 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03259  155 DEPLSALDAKLREELREELKELQReLGITTIYVTHDQEEALALADRIAVMNEGR 208
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
 46-257 2.13e-38

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 133.75  E-value: 2.13e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  46 KIDNLTKVYKSRKmgrILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQSI 124
Cdd:cd03225    1 ELKNLSFSYPDGA---RPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKeLRRKV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQF--DALFEDlTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLV 202
Cdd:cd03225   78 GLVFQNpdDQFFGP-TVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 203 FLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03225  157 LLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
 45-257 4.89e-38

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 133.23  E-value: 4.89e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQS 123
Cdd:COG1122    1 IELENLSFSY----PGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLReLRRK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQF--DALFEDlTAREHLELYTRLRGIPwKDE-ERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:COG1122   77 VGLVFQNpdDQLFAP-TVEEDVAFGPENLGLP-REEiRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPE 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG1122  155 VLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGR 211
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
 44-257 6.02e-38

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 133.23  E-value: 6.02e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELL--RVQ 121
Cdd:COG1137    3 TLEAENLVKSYGKRT-----VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPMhkRAR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSL 201
Cdd:COG1137   78 LGIGYLPQEASIFRKLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKF 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 202 VFLDEPTTGMDPKArrflwnlILDI------LKT-GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG1137  158 ILLDEPFAGVDPIA-------VADIqkiirhLKErGIGVLITDHNVRETLGICDRAYIISEGK 213
LivG COG0411
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ...
 44-257 3.61e-37

ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];


Pssm-ID: 440180 [Multi-domain]  Cd Length: 257  Bit Score: 131.70  E-value: 3.61e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQ 121
Cdd:COG0411    4 LLEVRGLTKRF-----GGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDItgLPPHRIAR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHLEL--YTRLRGIPWKDEERVVSWA-------------LEKLELSKYADMPAGTYSGGNK 186
Cdd:COG0411   79 LGIARTFQNPRLFPELTVLENVLVaaHARLGRGLLAALLRLPRARreereareraeelLERVGLADRADEPAGNLSYGQQ 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 187 RKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG0411  159 RRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDeRGITILLIEHDMDLVMGLADRIVVLDFGR 230
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
 40-266 7.87e-37

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 130.59  E-value: 7.87e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  40 ADNDMLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR 119
Cdd:COG1121    2 MMMPAIELENLTVSY-----GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 vqqsIGYCPQ---FDALFEdLTAREHLELYtRLRGIPW------KDEERVVSwALEKLELSKYADMPAGTYSGGNKRKLS 190
Cdd:COG1121   77 ----IGYVPQraeVDWDFP-ITVRDVVLMG-RYGRRGLfrrpsrADREAVDE-ALERVGLEDLADRPIGELSGGQQQRVL 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 191 TAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLgIMVNGRFKCLGSIQH 266
Cdd:COG1121  150 LARALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRV-LLLNRGLVAHGPPEE 224
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
 46-257 1.62e-36

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 127.36  E-value: 1.62e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  46 KIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK-ELLRVQQSI 124
Cdd:cd00267    1 EIENLSFRYGGRT-----ALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKlPLEELRRRI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFdalfedltarehlelytrlrgipwkdeervvswaleklelskyadmpagtySGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd00267   76 GYVPQL---------------------------------------------------SGGQRQRVALARALLLNPDLLLL 104

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd00267  105 DEPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
 45-269 3.00e-36

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 128.93  E-value: 3.00e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQQ 122
Cdd:TIGR04406   2 LVAENLIKSYKKRK-----VVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDIthLPMHERARL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  123 SIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWAL-EKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSL 201
Cdd:TIGR04406  77 GIGYLPQEASIFRKLTVEENIMAVLEIRKDLDRAEREERLEALlEEFQISHLRDNKAMSLSGGERRRVEIARALATNPKF 156

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197  202 VFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:TIGR04406 157 ILLDEPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVLAEGTPAEIVA 224
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
 45-257 9.54e-35

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 124.52  E-value: 9.54e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK------ELL 118
Cdd:cd03255    1 IELKNLSKTYGGGG-EKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKlsekelAAF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 119 RVQQsIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:cd03255   80 RRRH-IGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALAND 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEEcEALCTRLGIMVNGR 257
Cdd:cd03255  159 PKIILADEPTGNLDSETGKEVMELLRELNKeAGTTIVVVTHDPEL-AEYADRIIELRDGK 217
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
 46-262 1.00e-34

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 124.18  E-value: 1.00e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  46 KIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRvqqsIG 125
Cdd:cd03235    1 EVEDLTVSYGGHP-----VLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKR----IG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 126 YCPQ---FDALFEdLTARE--HLELYTRLRGIPW--KDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:cd03235   72 YVPQrrsIDRDFP-ISVRDvvLMGLYGHKGLFRRlsKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQD 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLgIMVNGRFKCLG 262
Cdd:cd03235  151 PDLLLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRV-LLLNRTVVASG 213
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
45-258 1.32e-34

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 123.77  E-value: 1.32e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK---ELLRvq 121
Cdd:COG4619    1 LELEGLSFRVGGKP---IL--SPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAmppPEWR-- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDlTAREHLELYTRLRGIPWkDEERVVSWaLEKLELSK-YADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:COG4619   74 RQVAYVPQEPALWGG-TVRDNLPFPFQLRERKF-DRERALEL-LERLGLPPdILDKPVERLSGGERQRLALIRALLLQPD 150

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:COG4619  151 VLLLDEPTSALDPENTRRVEELLREYLAeEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 29-267 1.72e-34

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 130.02  E-value: 1.72e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  29 ASERRRVLRGEADNDMLKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFI 108
Cdd:COG1123  245 AARGRAAPAAAAAEPLLEVRNLSKRYPVRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILF 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 109 GGSSIL----KELLRVQQSIGYCPQ--FDALFEDLTAREHLELYTRLRGIPWKDE-ERVVSWALEKLELS-KYADMPAGT 180
Cdd:COG1123  325 DGKDLTklsrRSLRELRRRVQMVFQdpYSSLNPRMTVGDIIAEPLRLHGLLSRAErRERVAELLERVGLPpDLADRYPHE 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 181 YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGRFK 259
Cdd:COG1123  405 LSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQReLGLTYLFISHDLAVVRYIADRVAVMYDGRIV 484


                 ....*...
gi 641957197 260 CLGSIQHL 267
Cdd:COG1123  485 EDGPTEEV 492
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
 44-263 2.10e-33

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 122.07  E-value: 2.10e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRkmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----LKELLR 119
Cdd:COG1120    1 MLEAENLSVGYGGR---PVL--DDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLaslsRRELAR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VqqsIGYCPQFDALFEDLTAREHLEL----YTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:COG1120   76 R---IAYVPQEPPAPFGLTVRELVALgrypHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARAL 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRflwnLILDILK-----TGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:COG1120  153 AQEPPLLLLDEPTSHLDLAHQL----EVLELLRrlareRGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGP 221
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 44-270 2.51e-33

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 123.66  E-value: 2.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYK----------------SRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAF 107
Cdd:COG4586    1 IIEVENLSKTYRvyekepglkgalkglfRREYREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 108 IGGSSILKELLRVQQSI----GycpQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAgtysg 183
Cdd:COG4586   81 VLGYVPFKRRKEFARRIgvvfG---QRSQLWWDLPAIDSFRLLKAIYRIPDAEYKKRLDELVELLDLGELLDTPV----- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 184 gnkRKLS--------TAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMV 254
Cdd:COG4586  153 ---RQLSlgqrmrceLAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRErGTTILLTSHDMDDIEALCDRVIVID 229

                        250
                 ....*....|....*.
gi 641957197 255 NGRFKCLGSIQHLKNR 270
Cdd:COG4586  230 HGRIIYDGSLEELKER 245
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
 45-253 5.00e-33

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 119.88  E-value: 5.00e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGssilKELLRVQQSI 124
Cdd:cd03293    1 LEVRNVSKTYGGGG-GAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDG----EPVTGPGPDR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYAD-MPAgTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:cd03293   76 GYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENaYPH-QLSGGMRQRVALARALAVDPDVLL 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRLGIM 253
Cdd:cd03293  155 LDEPFSALDALTREQLQEELLDIWrETGKTVLLVTHDIDEAVFLADRVVVL 205
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
 44-267 7.46e-33

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 119.99  E-value: 7.46e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLR 119
Cdd:cd03258    1 MIELKNVSKVFGDTG-GKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTllsgKELRK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYP 199
Cdd:cd03258   80 ARRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 200 SLVFLDEPTTGMDPKARRFLWNLILDI-LKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHL 267
Cdd:cd03258  160 KVLLCDEATSALDPETTQSILALLRDInRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEV 228
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
 44-257 8.14e-33

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 119.92  E-value: 8.14e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQ- 122
Cdd:cd03257    1 LLEVKNLSVSFPTGG-GSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKi 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 ---SIGYCPQ--FDALFEDLTAREHL-ELYtRLRGIPWKDE--ERVVSWALEKLELSK-YADMPAGTYSGGNKRKLSTAI 193
Cdd:cd03257   80 rrkEIQMVFQdpMSSLNPRMTIGEQIaEPL-RIHGKLSKKEarKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQRVAIAR 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 194 ALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03257  159 ALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEeLGLTLLFITHDLGVVAKIADRVAVMYAGK 223
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
 65-209 1.12e-32

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 116.98  E-value: 1.12e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   65 VDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQSIGYCPQFDALFEDLTAREHL 143
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDERKsLRKEIGYVFQDPQLFPRLTVRENL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  144 ELYTRLRGIPWKDEERVVSWALEKLELSKYAD----MPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTT 209
Cdd:pfam00005  81 RLGLLLKGLSKREKDARAEEALEKLGLGDLADrpvgERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
 40-269 1.44e-32

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 119.31  E-value: 1.44e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  40 ADNDMLKIDNLTKVYKSRKmgrILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----K 115
Cdd:COG1127    1 MSEPMIEVRNLTKSFGDRV---VL--DGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITglseK 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLRVQQSIGYCPQFDALFEDLTAREHLELYTR-LRGIPWKDEERVVSWALEKLELSKYAD-MPAGTySGGNKRKLSTAI 193
Cdd:COG1127   76 ELYELRRRIGMLFQGGALFDSLTVFENVAFPLReHTDLSEAEIRELVLEKLELVGLPGAADkMPSEL-SGGMRKRVALAR 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 194 ALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:COG1127  155 ALALDPEILLYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLA 231
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
 44-253 1.90e-32

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 119.81  E-value: 1.90e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGssilKELLRVQQS 123
Cdd:COG1116    7 ALELRGVSKRFPTGG-GGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDG----KPVTGPGPD 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:COG1116   82 RGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPEVLL 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRLGIM 253
Cdd:COG1116  162 MDEPFGALDALTRERLQDELLRLWqETGKTVLFVTHDVDEAVFLADRVVVL 212
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
 45-257 5.18e-32

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 117.54  E-value: 5.18e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQQ 122
Cdd:cd03224    1 LEVENLNAGY-----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDItgLPPHERARA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLELYTRLRGipwkdeERVVSWALEKL-----ELSKYADMPAGTYSGGNKRKLSTAIALIG 197
Cdd:cd03224   76 GIGYVPEGRRIFPELTVEENLLLGAYARR------RAKRKARLERVyelfpRLKERRKQLAGTLSGGEQQMLAIARALMS 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 198 YPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03224  150 RPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGR 209
LivF COG0410
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ...
 44-257 1.91e-31

ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];


Pssm-ID: 440179 [Multi-domain]  Cd Length: 236  Bit Score: 116.23  E-value: 1.91e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKelL----R 119
Cdd:COG0410    3 MLEVENLHAGY-----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITG--LpphrI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLELYTRLRGipwkdEERVVSWALEKL-----ELSKYADMPAGTYSGGNKRKLSTAIA 194
Cdd:COG0410   76 ARLGIGYVPEGRRIFPSLTVEENLLLGAYARR-----DRAEVRADLERVyelfpRLKERRRQRAGTLSGGEQQMLAIGRA 150

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 195 LIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG0410  151 LMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGR 213
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
 47-257 2.41e-31

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 116.28  E-value: 2.41e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYK----------------SRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG 110
Cdd:cd03267    3 VSNLSKSYRvyskepgligslkslfKRKYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 111 ssilkeLLRVQQSIGYCPQFDALFE-------DLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSG 183
Cdd:cd03267   83 ------LVPWKRRKKFLRRIGVVFGqktqlwwDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSL 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 184 GNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03267  157 GQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNReRGTTVLLTSHYMKDIEALARRVLVIDKGR 231
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
 47-259 3.23e-31

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 115.05  E-value: 3.23e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTkvYKSRKMGRILAVDRLCLgvRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI-LKELLRvqqSIG 125
Cdd:cd03226    2 IENIS--FSYKKGTEILDDLSLDL--YAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIkAKERRK---SIG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 126 YCPQ--FDALFEDlTAREhlELYTRLRGIPwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:cd03226   75 YVMQdvDYQLFTD-SVRE--ELLLGLKELD--AGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFK 259
Cdd:cd03226  150 FDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
DppF COG1124
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 44-272 3.25e-31

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440741 [Multi-domain]  Cd Length: 248  Bit Score: 116.06  E-value: 3.25e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMGRIlAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVqqs 123
Cdd:COG1124    1 MLEVRNLSVSYGQGGRRVP-VLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKA--- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 igYCPQFDALFED--------LTAREHLELYTRLRGIPwKDEERVVSwALEKLELSK-YADMPAGTYSGGNKRKLSTAIA 194
Cdd:COG1124   77 --FRRRVQMVFQDpyaslhprHTVDRILAEPLRIHGLP-DREERIAE-LLEQVGLPPsFLDRYPHQLSGGQRQRVAIARA 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 195 LIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNRSE 272
Cdd:COG1124  153 LILEPELLLLDEPTSALDVSVQAEILNLLKDLREeRGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPK 231
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
48-257 8.15e-31

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 121.00  E-value: 8.15e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  48 DNLTkvyksRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGYC 127
Cdd:NF033858 270 RGLT-----MRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAGDIATRRRVGYM 344

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 128 PQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEP 207
Cdd:NF033858 345 SQAFSLYGELTVRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEP 424

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 641957197 208 TTGMDPKARRFLWNLILDiL--KTGRSVVLTSHSMEECEaLCTRLGIMVNGR 257
Cdd:NF033858 425 TSGVDPVARDMFWRLLIE-LsrEDGVTIFISTHFMNEAE-RCDRISLMHAGR 474
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
 47-269 8.64e-31

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 114.52  E-value: 8.64e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYKSRkmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLRVQQ 122
Cdd:cd03261    3 LRGLTKSFGGR---TVL--KGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISglseAELYRLRR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTA--------REHLELytrlrgipwkDEERVVSWALEKLE---LSKYAD-MPAgTYSGGNKRKLS 190
Cdd:cd03261   78 RMGMLFQSGALFDSLTVfenvafplREHTRL----------SEEEIREIVLEKLEavgLRGAEDlYPA-ELSGGMKKRVA 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 191 TAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:cd03261  147 LARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
 44-257 2.02e-30

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 116.35  E-value: 2.02e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKelLRVQQ- 122
Cdd:COG3842    5 ALELENVSKRY-----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTG--LPPEKr 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLV 202
Cdd:COG3842   78 NVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 203 FLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG3842  158 LLDEPLSALDAKLREEMREELRRLQReLGITFIYVTHDQEEALALADRIAVMNDGR 213
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
 42-257 3.24e-30

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 118.08  E-value: 3.24e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG---DESTTGGEAFIGGSSILK--E 116
Cdd:COG1123    2 TPLLEVRDLSVRYPG---GDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGllpHGGRISGEVLLDGRDLLElsE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 LLRVQQsIGYCPQ-FDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:COG1123   79 ALRGRR-IGMVFQdPMTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMAL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG1123  158 ALDPDLLIADEPTTALDVTTQAEILDLLRELQReRGTTVLLITHDLGVVAEIADRVVVMDDGR 220
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
42-257 7.99e-30

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 111.67  E-value: 7.99e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKE--- 116
Cdd:COG1136    2 SPLLELRNLTKSYGTGE-GEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDIssLSErel 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 -LLRvQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:COG1136   81 aRLR-RRHIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARAL 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRflwnLILDILK-----TGRSVVLTSHSmEECEALCTRLGIMVNGR 257
Cdd:COG1136  160 VNRPKLILADEPTGNLDSKTGE----EVLELLRelnreLGTTIVMVTHD-PELAARADRVIRLRDGR 221
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
 45-263 7.03e-29

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 109.70  E-value: 7.03e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKE-LLRVQQS 123
Cdd:cd03295    1 IEFENVTKRYGGGKK----AVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQdPVELRRK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGipWKdEERVVSWALEKLEL-----SKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:cd03295   77 IGYVIQQIGLFPHMTVEENIALVPKLLK--WP-KEKIRERADELLALvgldpAEFADRYPHELSGGQQQRVGVARALAAD 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:cd03295  154 PPLLLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGT 219
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
 45-263 4.59e-28

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 107.32  E-value: 4.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKeLLRVQQSI 124
Cdd:cd03300    1 IELENVSKFY-----GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITN-LPPHKRPV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03300   75 NTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLL 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 205 DEPTTGMDPKARRFLwNLILDIL--KTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:cd03300  155 DEPLGALDLKLRKDM-QLELKRLqkELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGT 214
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
 45-263 3.07e-27

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 105.36  E-value: 3.07e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGS--SILKELLRVQQ 122
Cdd:PRK10895   4 LTAKNLAKAYKGRRV-----VEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEdiSLLPLHARARR 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLELYTRLR-GIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSL 201
Cdd:PRK10895  79 GIGYLPQEASIFRRLSVYDNLMAVLQIRdDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKF 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 202 VFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:PRK10895 159 ILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGT 220
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
44-241 3.85e-27

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 104.75  E-value: 3.85e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKsrkmGRILAVDRLCLGVRPGE-CFgLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK----ELL 118
Cdd:COG2884    1 MIRFENVSKRYP----GGREALSDVSLEIEKGEfVF-LTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRlkrrEIP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 119 RVQQSIGYCPQfDA-LFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIG 197
Cdd:COG2884   76 YLRRRIGVVFQ-DFrLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVN 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 641957197 198 YPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:COG2884  155 RPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLE 198
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
 42-264 4.48e-27

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 105.16  E-value: 4.48e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYK-----------------SRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGG 104
Cdd:COG1134    2 SSMIEVENVSKSYRlyhepsrslkelllrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 105 EAFIGG--SSILkELlrvqqSIGycpqFDAlfeDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYS 182
Cdd:COG1134   82 RVEVNGrvSALL-EL-----GAG----FHP---ELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQPVKTYS 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 183 GGNKRKLSTAIALIGYPSLVFLDEPTTGMDP----KARRFlwnlILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:COG1134  149 SGMRARLAFAVATAVDPDILLVDEVLAVGDAafqkKCLAR----IRELRESGRTVIFVSHSMGAVRRLCDRAIWLEKGRL 224


                 ....*.
gi 641957197 259 KCLGSI 264
Cdd:COG1134  225 VMDGDP 230
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
 45-257 8.86e-27

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 102.65  E-value: 8.86e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---LKELLRVQ 121
Cdd:cd03229    1 LELKNVSKRY-----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLtdlEDELPPLR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHLELytrlrgipwkdeervvswALeklelskyadmpagtySGGNKRKLSTAIALIGYPSL 201
Cdd:cd03229   76 RRIGMVFQDFALFPHLTVLENIAL------------------GL----------------SGGQQQRVALARALAMDPDV 121

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 202 VFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03229  122 LLLDEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
57-270 9.56e-27

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 106.74  E-value: 9.56e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  57 RKMGRILAVDRLCLGVRPGECFGLLGVNGAG--KTTTFKMLTGDESTTGGEAFIGGSSILKELLRvqqSIG-YCPQFDAL 133
Cdd:NF000106  21 KHFGEVKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHV*GPDAGRRPWRF*TWCANRRALRR---TIG*HRPVR*GR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 FEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDP 213
Cdd:NF000106  98 RESFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDP 177

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 214 KARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:NF000106 178 RTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVDELKTK 234
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
 72-257 1.10e-26

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 102.63  E-value: 1.10e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTG--DESTTGGEAFIGGSSILKELLRvqQSIGYCPQFDALFEDLTAREHLELYTRL 149
Cdd:cd03213   32 AKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFR--KIIGYVPQDDILHPTLTVRETLMFAAKL 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 150 RGIpwkdeervvswaleklelskyadmpagtySGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT 229
Cdd:cd03213  110 RGL-----------------------------SGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADT 160

                        170       180
                 ....*....|....*....|....*....
gi 641957197 230 GRSVVLTSHS-MEECEALCTRLGIMVNGR 257
Cdd:cd03213  161 GRTIICSIHQpSSEIFELFDKLLLLSQGR 189
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
 45-262 1.86e-26

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 102.72  E-value: 1.86e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlKELLRVQQSI 124
Cdd:cd03301    1 VELENVTKRFGNVT-----ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDV-TDLPPKDRDI 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03301   75 AMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLM 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLG 262
Cdd:cd03301  155 DEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQIQQIG 213
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 29-258 1.10e-25

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 105.65  E-value: 1.10e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   29 ASERRRVLRGEADNDMLKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAF- 107
Cdd:TIGR03269 264 VSEVEKECEVEVGEPIIKVRNVSKRYISVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNv 343

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  108 -IGGSSI------LKELLRVQQSIGYCPQFDALFedlTAREHLELYTRLRGIPWKDE---------ERVVSWALEKLE-- 169
Cdd:TIGR03269 344 rVGDEWVdmtkpgPDGRGRAKRYIGILHQEYDLY---PHRTVLDNLTEAIGLELPDElarmkavitLKMVGFDEEKAEei 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  170 LSKYADmpagTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCT 248
Cdd:TIGR03269 421 LDKYPD----ELSEGERHRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCD 496

                         250
                  ....*....|
gi 641957197  249 RLGIMVNGRF 258
Cdd:TIGR03269 497 RAALMRDGKI 506
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
 44-240 1.26e-25

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 101.61  E-value: 1.26e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLtkvykSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---------L 114
Cdd:PRK11300   5 LLSVSGL-----MMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIeglpghqiaR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 115 KELLRVQQSIgycpqfdALFEDLTARE------HLELYTRL----------RGIPWKDEERVVSWaLEKLELSKYADMPA 178
Cdd:PRK11300  80 MGVVRTFQHV-------RLFREMTVIEnllvaqHQQLKTGLfsgllktpafRRAESEALDRAATW-LERVGLLEHANRQA 151

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 179 GTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLIlDILKT--GRSVVLTSHSM 240
Cdd:PRK11300 152 GNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELI-AELRNehNVTVLLIEHDM 214
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
 72-238 1.75e-25

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 100.42  E-value: 1.75e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTG---DESTTGGEAFIGGSSILKELlrVQQSIGYCPQFDALFEDLTAREHLELYTR 148
Cdd:cd03234   30 VESGQVMAILGSSGSGKTTLLDAISGrveGGGTTSGQILFNGQPRKPDQ--FQKCVAYVRQDDILLPGLTVRETLTYTAI 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 149 LR-GIPWKDEERVVSWalEKLELSKYADMPAGTY-----SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPkarrFLWNL 222
Cdd:cd03234  108 LRlPRKSSDAIRKKRV--EDVLLRDLALTRIGGNlvkgiSGGERRRVSIAVQLLWDPKVLILDEPTSGLDS----FTALN 181

                        170       180
                 ....*....|....*....|
gi 641957197 223 ILDILK----TGRSVVLTSH 238
Cdd:cd03234  182 LVSTLSqlarRNRIVILTIH 201
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
 45-265 2.38e-25

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 100.49  E-value: 2.38e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlKELLRVQQSI 124
Cdd:cd03299    1 LKVENLSKDWKEFK------LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDI-TNLPPEKRDI 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03299   74 SYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLL 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVL-TSHSMEECEALCTRLGIMVNGRFKCLGSIQ 265
Cdd:cd03299  154 DEPFSALDVRTKEKLREELKKIRKEFGVTVLhVTHDFEEAWALADKVAIMLNGKLIQVGKPE 215
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
 42-257 2.85e-25

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 100.54  E-value: 2.85e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRkmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDES-TTGGEAFI-----GGSSILK 115
Cdd:COG1119    1 DPLLELRNVTVRRGGK---TIL--DDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPpTYGNDVRLfgerrGGEDVWE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 elLRvqQSIGYC-PQFDALF-EDLTARE--------HLELYtrlRGIPWKDEERVVSWaLEKLELSKYADMPAGTYSGGN 185
Cdd:COG1119   76 --LR--KRIGLVsPALQLRFpRDETVLDvvlsgffdSIGLY---REPTDEQRERAREL-LELLGLAHLADRPFGTLSQGE 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTG-RSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG1119  148 QRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVEEIPPGITHVLLLKDGR 220
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
 67-238 3.18e-25

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 98.97  E-value: 3.18e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   67 RLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGYCPQFDALFEDLTAREHLELY 146
Cdd:TIGR01189  18 GLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQRDEPHENILYLGHLPGLKPELSALENLHFW 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  147 TRLRGipwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI 226
Cdd:TIGR01189  98 AAIHG----GAQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAH 173

                         170
                  ....*....|..
gi 641957197  227 LKTGRSVVLTSH 238
Cdd:TIGR01189 174 LARGGIVLLTTH 185
COG4674 COG4674
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 42-269 3.58e-25

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443710 [Multi-domain]  Cd Length: 250  Bit Score: 100.19  E-value: 3.58e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK--ELLR 119
Cdd:COG4674    8 GPILYVEDLTVSFDGFK-----ALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVLFGGTDLTGldEHEI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLEL-YTRLRGiPWK---------DEERVVSwALEKLELSKYADMPAGTYSGGNKRKL 189
Cdd:COG4674   83 ARLGIGRKFQKPTVFEELTVFENLELaLKGDRG-VFAslfarltaeERDRIEE-VLETIGLTDKADRLAGLLSHGQKQWL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTgRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:COG4674  161 EIGMLLAQDPKLLLLDEPVAGMTDAETERTAELLKSLAGK-HSVVVVEHDMEFVRQIARKVTVLHQGSVLAEGSLDEVQA 239
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
 46-262 3.98e-25

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 98.28  E-value: 3.98e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  46 KIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----LKELLRVq 121
Cdd:cd03214    1 EVENLSVGYGGRT-----VLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLaslsPKELARK- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 qsIGYCPQfdalfedltarehlelytrlrgipwkdeervvswALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSL 201
Cdd:cd03214   75 --IAYVPQ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPI 118

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 202 VFLDEPTTGMDPKARrflwNLILDILK-----TGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLG 262
Cdd:cd03214  119 LLLDEPTSHLDIAHQ----IELLELLRrlareRGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
 72-238 1.81e-24

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 96.93  E-value: 1.81e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTG--DESTTGGEAFIGGSSILKELLRvqqSIGYCPQFDALFEDLTAREHLELYTRL 149
Cdd:cd03232   30 VKPGTLTALMGESGAGKTTLLDVLAGrkTAGVITGEILINGRPLDKNFQR---STGYVEQQDVHSPNLTVREALRFSALL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 150 RGIpwkdeervvswaleklelskyadmpagtySGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT 229
Cdd:cd03232  107 RGL-----------------------------SVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLADS 157


                 ....*....
gi 641957197 230 GRSVVLTSH 238
Cdd:cd03232  158 GQAILCTIH 166
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
 45-257 2.53e-24

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 97.25  E-value: 2.53e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG-----DESTTGGEAFIGGSSILK---E 116
Cdd:cd03260    1 IELRDLNVYYGDKH-----ALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGKDIYDldvD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 LLRVQQSIGYCPQFDALFeDLTAREHLELYTRLRGIPWKDE-ERVVSWALEKLELSKYAD--MPAGTYSGGNKRKLSTAI 193
Cdd:cd03260   76 VLELRRRVGMVFQKPNPF-PGSIYDNVAYGLRLHGIKLKEElDERVEEALRKAALWDEVKdrLHALGLSGGQQQRLCLAR 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 194 ALIGYPSLVFLDEPTTGMDPKARRFLWNLILDiLKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03260  155 ALANEPEVLLLDEPTSALDPISTAKIEELIAE-LKKEYTIVIVTHNMQQAARVADRTAFLLNGR 217
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
44-263 4.82e-24

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 99.52  E-value: 4.82e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRkmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSiLKELLRVQQS 123
Cdd:PRK11607  19 LLEIRNLTKSFDGQ-----HAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVD-LSHVPPYQRP 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:PRK11607  93 INMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLL 172

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:PRK11607 173 LDEPMGALDKKLRDRMQLEVVDILeRVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGE 233
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 72-238 6.09e-24

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 100.95  E-value: 6.09e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    72 VRPGECFGLLGVNGAGKTTTFKMLTGDEST---TGGEAFIGGSSILKELlrvQQSIGYCPQFDALFEDLTAREHLELYTR 148
Cdd:TIGR00956  786 VKPGTLTALMGASGAGKTTLLNVLAERVTTgviTGGDRLVNGRPLDSSF---QRSIGYVQQQDLHLPTSTVRESLRFSAY 862

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   149 LR---GIPWKDEERVVSWALEKLELSKYADMPAGTYSGG----NKRKLSTAIALIGYP-SLVFLDEPTTGMDPKARRFLW 220
Cdd:TIGR00956  863 LRqpkSVSKSEKMEYVEEVIKLLEMESYADAVVGVPGEGlnveQRKRLTIGVELVAKPkLLLFLDEPTSGLDSQTAWSIC 942

                          170
                   ....*....|....*...
gi 641957197   221 NLILDILKTGRSVVLTSH 238
Cdd:TIGR00956  943 KLMRKLADHGQAILCTIH 960
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
62-257 8.22e-24

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 100.09  E-value: 8.22e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  62 ILAVDRLCLG---------VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlkELLRVQQS----IGYCP 128
Cdd:COG1129  256 VLEVEGLSVGgvvrdvsfsVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPV--RIRSPRDAiragIAYVP 333

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 129 ---QFDALFEDLTARE-----HLELYTRLRGIPWKDEERVVSWALEKLELsKYADM--PAGTYSGGNKRKLSTAIALIGY 198
Cdd:COG1129  334 edrKGEGLVLDLSIREnitlaSLDRLSRGGLLDRRRERALAEEYIKRLRI-KTPSPeqPVGNLSGGNQQKVVLAKWLATD 412

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG1129  413 PKVLILDEPTRGIDVGAKAEIYRLIRELAAEGKAVIVISSELPELLGLSDRILVMREGR 471
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
 45-257 1.16e-23

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 95.68  E-value: 1.16e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRK-----------------MGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAF 107
Cdd:cd03220    1 IELENVSKSYPTYKggssslkklgilgrkgeVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 108 IGG--SSILkellrvqqSIGYcpqfdALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGN 185
Cdd:cd03220   81 VRGrvSSLL--------GLGG-----GFNPELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGM 147

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03220  148 KARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGK 219
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
 45-257 1.61e-23

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 95.71  E-value: 1.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLRV 120
Cdd:cd03256    1 IEVENLSKTYPNGKK----ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINklkgKALRQL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQFDALFEDLTAREHLeLYTRL------RGI--PWKDEERVVSW-ALEKLELSKYADMPAGTYSGGNKRKLST 191
Cdd:cd03256   77 RRQIGMIFQQFNLIERLSVLENV-LSGRLgrrstwRSLfgLFPKEEKQRALaALERVGLLDKAYQRADQLSGGQQQRVAI 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 192 AIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03256  156 ARALMQQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREYADRIVGLKDGR 222
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
 45-263 3.83e-23

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 94.71  E-value: 3.83e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRvQQSI 124
Cdd:cd03296    3 IEVRNVSKRF-----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQ-ERNV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREH----LELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:cd03296   77 GFVFQHYALFRHMTVFDNvafgLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPK 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:cd03296  157 VLLLDEPFGALDAKVRKELRRWLRRLHdELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGT 220
cbiO PRK13637
energy-coupling factor transporter ATPase;
45-264 3.87e-23

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 95.50  E-value: 3.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKE---LLRVQ 121
Cdd:PRK13637   3 IKIENLTHIYMEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKkvkLSDIR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFD--ALFEDlTAREHLELYTRLRGIPWKDEERVVSWALE--KLELSKYADMPAGTYSGGNKRKLSTAIALIG 197
Cdd:PRK13637  83 KKVGLVFQYPeyQLFEE-TIEKDIAFGPINLGLSEEEIENRVKRAMNivGLDYEDYKDKSPFELSGGQKRRVAIAGVVAM 161

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 198 YPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSI 264
Cdd:PRK13637 162 EPKILILDEPTAGLDPKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTP 229
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
 74-257 6.73e-23

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 93.13  E-value: 6.73e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  74 PGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG----SSILKELLRVQQ-SIGYCPQFDALFEDLTAREHLEL-YT 147
Cdd:cd03297   22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGtvlfDSRKKINLPPQQrKIGLVFQQYALFPHLNVRENLAFgLK 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 148 RLRGIPWKDEERVVswaLEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIL 227
Cdd:cd03297  102 RKRNREDRISVDEL---LDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIK 178

                        170       180       190
                 ....*....|....*....|....*....|.
gi 641957197 228 KT-GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03297  179 KNlNIPVIFVTHDLSEAEYLADRIVVMEDGR 209
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
 45-257 1.04e-22

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 93.86  E-value: 1.04e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSR-------------------KMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGE 105
Cdd:cd03294    1 IKIKGLYKIFGKNpqkafkllakgkskeeilkKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 106 AFIGGSSIL----KELLRVQ-QSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGT 180
Cdd:cd03294   81 VLIDGQDIAamsrKELRELRrKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDE 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 181 YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03294  161 LSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQaELQKTIVFITHDLDEALRLGDRIAIMKDGR 238
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
41-258 1.81e-22

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 96.24  E-value: 1.81e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  41 DNDMLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlkELLRV 120
Cdd:COG1129    1 AEPLLEMRGISKSF-----GGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPV--RFRSP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQS----IGYCPQFDALFEDLTAREHL---ELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAI 193
Cdd:COG1129   74 RDAqaagIAIIHQELNLVPNLSVAENIflgREPRRGGLIDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIAR 153

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 194 ALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:COG1129  154 ALSRDARVLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRL 218
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
44-257 3.34e-22

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 93.99  E-value: 3.34e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLR 119
Cdd:COG1135    1 MIELENLSKTFPTKG-GPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTalseRELRA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPwKDE--ERVvswaLEKLE---LSKYADmpagTY----SGGNKRKLS 190
Cdd:COG1135   80 ARRKIGMIFQHFNLLSSRTVAENVALPLEIAGVP-KAEirKRV----AELLElvgLSDKAD----AYpsqlSGGQKQRVG 150

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 191 TAIALIGYPSLVFLDEPTTGMDPKARRflwnLILDILK-----TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG1135  151 IARALANNPKVLLCDEATSALDPETTR----SILDLLKdinreLGLTIVLITHEMDVVRRICDRVAVLENGR 218
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
 49-241 3.60e-22

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 91.32  E-value: 3.60e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  49 NLTKVYKsrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK------ELLRvqQ 122
Cdd:cd03292    5 NVTKTYP----NGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlrgraiPYLR--R 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELS-KYADMPAGtYSGGNKRKLSTAIALIGYPSL 201
Cdd:cd03292   79 KIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLShKHRALPAE-LSGGEQQRVAIARAIVNSPTI 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 641957197 202 VFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:cd03292  158 LIADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKE 197
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 62-258 4.06e-22

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 90.18  E-value: 4.06e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  62 ILAVDRLCLG---------VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQQSIGYCP-- 128
Cdd:cd03215    4 VLEVRGLSVKgavrdvsfeVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVtrRSPRDAIRAGIAYVPed 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 129 -QFDALFEDLTAREHLELYTRLrgipwkdeervvswaleklelskyadmpagtySGGNKRKLSTAIALIGYPSLVFLDEP 207
Cdd:cd03215   84 rKREGLVLDLSVAENIALSSLL--------------------------------SGGNQQKVVLARWLARDPRVLILDEP 131

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 641957197 208 TTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:cd03215  132 TRGVDVGAKAEIYRLIRELADAGKAVLLISSELDELLGLCDRILVMYEGRI 182
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
 64-272 6.90e-22

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 94.83  E-value: 6.90e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlKELLR--VQQSIGYCPQFDALFEDlTARE 141
Cdd:COG4987  350 VLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDL-RDLDEddLRRRIAVVPQRPHLFDT-TLRE 427

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLelytRLrGIPWKDEERVVSwALEKLELSKY-ADMPAG----------TYSGGNKRKLSTAIALIGYPSLVFLDEPTTG 210
Cdd:COG4987  428 NL----RL-ARPDATDEELWA-ALERVGLGDWlAALPDGldtwlgeggrRLSGGERRRLALARALLRDAPILLLDEPTEG 501

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 211 MDPKARRFLWNLILDILKtGRSVVLTSHSMEECEAlCTRLGIMVNGRFKCLGSIQHLKNRSE 272
Cdd:COG4987  502 LDAATEQALLADLLEALA-GRTVLLITHRLAGLER-MDRILVLEDGRIVEQGTHEELLAQNG 561
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
 19-238 1.41e-21

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 93.75  E-value: 1.41e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  19 QPIEDDDEDVASERRRvLRGEadndmLKIDNLTKVYKSRKmgrILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGD 98
Cdd:COG2274  454 LPPEREEGRSKLSLPR-LKGD-----IELENVSFRYPGDS---PPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGL 524

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  99 ESTTGGEAFIGG---SSILKELLRvqQSIGYCPQFDALFEDlTAREHLELytrlrGIPWKDEERVVsWALEKLELSKY-A 174
Cdd:COG2274  525 YEPTSGRILIDGidlRQIDPASLR--RQIGVVLQDVFLFSG-TIRENITL-----GDPDATDEEII-EAARLAGLHDFiE 595

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 175 DMPAG----------TYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSH 238
Cdd:COG2274  596 ALPMGydtvvgeggsNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRLLK-GRTVIIIAH 668
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
 62-257 2.07e-21

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 89.57  E-value: 2.07e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  62 ILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlKEL----LRvqQSIGYCPQFDALFEDl 137
Cdd:cd03245   17 IPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDI-RQLdpadLR--RNIGYVPQDVTLFYG- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 138 TAREHLELytrlrGIPWKDEERVVSwALEKLELSKYA-------DMPAG----TYSGGNKRKLSTAIALIGYPSLVFLDE 206
Cdd:cd03245   93 TLRDNITL-----GAPLADDERILR-AAELAGVTDFVnkhpnglDLQIGergrGLSGGQRQAVALARALLNDPPILLLDE 166

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 207 PTTGMDPKA-RRFLWNliLDILKTGRSVVLTSH--SMEEceaLCTRLGIMVNGR 257
Cdd:cd03245  167 PTSAMDMNSeERLKER--LRQLLGDKTLIIITHrpSLLD---LVDRIIVMDSGR 215
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
 64-257 4.46e-21

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 89.75  E-value: 4.46e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---LKELLRVQQSIGYCPQF--DALFEDlT 138
Cdd:PRK13639  17 ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIkydKKSLLEVRKTVGIVFQNpdDQLFAP-T 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 139 AREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRF 218
Cdd:PRK13639  96 VEEDVAFGPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQ 175

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 641957197 219 LWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK13639 176 IMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGK 214
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
44-238 4.96e-21

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 87.94  E-value: 4.96e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTkvykSRKMGRILaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQS 123
Cdd:PRK13538   1 MLEARNLA----CERDERIL-FSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDEYHQD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREHLELYTRLRGIPwkDEERVVSwALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:PRK13538  76 LLYLGHQPGIKTELTALENLRFYQRLHGPG--DDEALWE-ALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWI 152

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 641957197 204 LDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:PRK13538 153 LDEPFTAIDKQGVARLEALLAQHAEQGGMVILTTH 187
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
 45-257 7.64e-21

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 86.33  E-value: 7.64e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlkellrvqqsi 124
Cdd:cd03216    1 LELRGITKRF-----GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEV----------- 64

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 gycpQFDALFEdltAREHlelytrlrGIpwkdeeRVVSwaleklelskyadmpagTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03216   65 ----SFASPRD---ARRA--------GI------AMVY-----------------QLSVGERQMVEIARALARNARLLIL 106

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 205 DEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03216  107 DEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGR 159
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 47-238 1.82e-20

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 90.51  E-value: 1.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYKSRKmgrILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGssilkellrvQQSIGY 126
Cdd:COG0488    1 LENLSKSFGGRP---LL--DDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPK----------GLRIGY 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 127 CPQFDALFEDLTAREHL--------ELYTRLRGI------PWKDEERVVS----------WALE--------KLELSK-Y 173
Cdd:COG0488   66 LPQEPPLDDDLTVLDTVldgdaelrALEAELEELeaklaePDEDLERLAElqeefealggWEAEaraeeilsGLGFPEeD 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 174 ADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTgrsVVLTSH 238
Cdd:COG0488  146 LDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPGT---VLVVSH 207
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
 44-257 1.82e-20

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 88.57  E-value: 1.82e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG---DESTTGGEAFIGGSSIL----KE 116
Cdd:COG0444    1 LLEVRNLKVYFPTRR-GVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGllpPPGITSGEILFDGEDLLklseKE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 LLRV-QQSIGYCPQ--FDALfeD--LTAREHL-ELYTRLRGIPWKD-EERVVSwALEKLELS---KYADMPAGTYSGGNK 186
Cdd:COG0444   80 LRKIrGREIQMIFQdpMTSL--NpvMTVGDQIaEPLRIHGGLSKAEaRERAIE-LLERVGLPdpeRRLDRYPHELSGGMR 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 187 RKLSTAIALIGYPSLVFLDEPTTGMDP--KARrflwnlILDILK-----TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG0444  157 QRVMIARALALEPKLLIADEPTTALDVtiQAQ------ILNLLKdlqreLGLAILFITHDLGVVAEIADRVAVMYAGR 228
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
 44-257 2.29e-20

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 88.70  E-value: 2.29e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLR 119
Cdd:PRK11153   1 MIELKNISKVFPQGG-RTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTalseKELRK 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYAD-MPAgTYSGGNKRKLSTAIALIGY 198
Cdd:PRK11153  80 ARRQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADrYPA-QLSGGQKQRVAIARALASN 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 199 PSLVFLDEPTTGMDPKARRflwnLILDILKT-----GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK11153 159 PKVLLCDEATSALDPATTR----SILELLKDinrelGLTIVLITHEMDVVKRICDRVAVIDAGR 218
AztA NF040873
zinc ABC transporter ATP-binding protein AztA;
64-242 2.81e-20

zinc ABC transporter ATP-binding protein AztA;


Pssm-ID: 468810 [Multi-domain]  Cd Length: 191  Bit Score: 85.75  E-value: 2.81e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSilkellrvqqSIGYCPQFDALFEDL--TARE 141
Cdd:NF040873   7 VLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGA----------RVAYVPQRSEVPDSLplTVRD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLELYTRLRGIPW----KDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARR 217
Cdd:NF040873  77 LVAMGRWARRGLWrrltRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRE 156

                        170       180
                 ....*....|....*....|....*
gi 641957197 218 FLWNLILDILKTGRSVVLTSHSMEE 242
Cdd:NF040873 157 RIIALLAEEHARGATVVVVTHDLEL 181
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 62-258 4.92e-20

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 88.95  E-value: 4.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  62 ILAVDRLC--------LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQQSIGYCP--- 128
Cdd:PRK15439 268 VLTVEDLTgegfrnisLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEInaLSTAQRLARGLVYLPedr 347

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 129 QFDALFEDLTAREHLELYTRLRGIPWKDEERvvswalEKLELSKY----------ADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:PRK15439 348 QSSGLYLDAPLAWNVCALTHNRRGFWIKPAR------ENAVLERYrralnikfnhAEQAARTLSGGNQQKVLIAKCLEAS 421

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:PRK15439 422 PQLLIVDEPTRGVDVSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
cbiO PRK13643
energy-coupling factor transporter ATPase;
44-242 7.27e-20

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 86.71  E-value: 7.27e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIG-----GSSILKELL 118
Cdd:PRK13643   1 MIKFEKVNYTYQPNSPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGdivvsSTSKQKEIK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 119 RVQQSIGYCPQF--DALFEDlTAREHLELYTRLRGIPWKDEERVVSWALEKLELSK-YADMPAGTYSGGNKRKLSTAIAL 195
Cdd:PRK13643  81 PVRKKVGVVFQFpeSQLFEE-TVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADeFWEKSPFELSGGQMRRVAIAGIL 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEE 242
Cdd:PRK13643 160 AMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDD 206
PhnL COG4778
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ...
 44-250 9.32e-20

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];


Pssm-ID: 443809 [Multi-domain]  Cd Length: 229  Bit Score: 85.18  E-value: 9.32e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMG--RILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFI--GGSSI-L---- 114
Cdd:COG4778    4 LLEVENLSKTFTLHLQGgkRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVrhDGGWVdLaqas 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 115 -KELLRV-QQSIGYCPQF--------------DALFEDLTAREH-----LELYTRLrGIPwkdeERVvsWALeklelsky 173
Cdd:COG4778   84 pREILALrRRTIGYVSQFlrviprvsaldvvaEPLLERGVDREEararaRELLARL-NLP----ERL--WDL-------- 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 174 admPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRL 250
Cdd:COG4778  149 ---PPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKARGTAIIGIFHDEEVREAVADRV 222
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
44-269 1.13e-19

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 87.92  E-value: 1.13e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKvyksrKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQ 121
Cdd:PRK09700   5 YISMAGIGK-----SFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYnkLDHKLAAQ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHL---ELYTR-LRGIP---WKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIA 194
Cdd:PRK09700  80 LGIGIIYQELSVIDELTVLENLyigRHLTKkVCGVNiidWREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKT 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 195 LIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:PRK09700 160 LMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVSDVSN 234
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
44-257 1.54e-19

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 85.07  E-value: 1.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLR 119
Cdd:PRK11231   2 TLRTENLTVGYGTKRI-----LNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISmlssRQLAR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 vqqSIGYCPQFDALFEDLTARE--------HLELYTRLRGipwKDEERVvSWALEKLELSKYADMPAGTYSGGNKRKLST 191
Cdd:PRK11231  77 ---RLALLPQHHLTPEGITVRElvaygrspWLSLWGRLSA---EDNARV-NQAMEQTRINHLADRRLTDLSGGQRQRAFL 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 192 AIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK11231 150 AMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGH 215
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
 44-262 1.69e-19

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 87.20  E-value: 1.69e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLtkvykSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQ 122
Cdd:PRK09536   3 MIDVSDL-----SVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARaASR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFEDLTAREHLELYT---RLRGIPW-KDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:PRK09536  78 RVASVPQDTSLSFEFDVRQVVEMGRtphRSRFDTWtETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQA 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 199 PSLVFLDEPTTGMD-PKARRFLwNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLG 262
Cdd:PRK09536 158 TPVLLLDEPTASLDiNHQVRTL-ELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
 68-239 3.80e-19

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 83.00  E-value: 3.80e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  68 LCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlkELLRVQQSIGYCPQFDALFEDLTAREHLELYT 147
Cdd:PRK13539  21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI--DDPDVAEACHYLGHRNAMKPALTVAENLEFWA 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 148 RLRGipwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIL 227
Cdd:PRK13539  99 AFLG----GEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAHL 174

                        170
                 ....*....|..
gi 641957197 228 KTGRSVVLTSHS 239
Cdd:PRK13539 175 AQGGIVIAATHI 186
TauB COG4525
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
44-253 4.97e-19

ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443596 [Multi-domain]  Cd Length: 262  Bit Score: 83.76  E-value: 4.97e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKellrvqqs 123
Cdd:COG4525    3 MLTVRHVSVRYPGGG-QPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTG-------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 igycP--------QFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:COG4525   74 ----PgadrgvvfQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARAL 149

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRLGIM 253
Cdd:COG4525  150 AADPRFLLMDEPFGALDALTREQMQELLLDVWqRTGKGVFLITHSVEEALFLATRLVVM 208
PLN03140 PLN03140
ABC transporter G family member; Provisional
 73-238 5.56e-19

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 86.44  E-value: 5.56e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   73 RPGECFGLLGVNGAGKTTTFKMLTGDEstTGGeaFIGGSSILKELLRVQQSI----GYCPQFDALFEDLTAREHL--ELY 146
Cdd:PLN03140  904 RPGVLTALMGVSGAGKTTLMDVLAGRK--TGG--YIEGDIRISGFPKKQETFarisGYCEQNDIHSPQVTVRESLiySAF 979

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  147 TRLRGIPWKDEE-RVVSWALEKLELSKYAD----MPAGT-YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLW 220
Cdd:PLN03140  980 LRLPKEVSKEEKmMFVDEVMELVELDNLKDaivgLPGVTgLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVM 1059

                         170
                  ....*....|....*...
gi 641957197  221 NLILDILKTGRSVVLTSH 238
Cdd:PLN03140 1060 RTVRNTVDTGRTVVCTIH 1077
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
41-242 5.64e-19

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 83.98  E-value: 5.64e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  41 DNDMLKIDNLTKVYKSRKMG-RILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG--SSILKEL 117
Cdd:PRK13633   1 MNEMIKCKNVSYKYESNEEStEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGldTSDEENL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 118 LRVQQSIGYCPQ------FDALFEDLTA--REHLelytrlrGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKL 189
Cdd:PRK13633  81 WDIRNKAGMVFQnpdnqiVATIVEEDVAfgPENL-------GIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRV 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEE 242
Cdd:PRK13633 154 AIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHYMEE 207
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
 73-267 7.24e-19

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 85.87  E-value: 7.24e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   73 RPGECFGLLGVNGAGKTT-----TFKMLTGdeSTTGGEAFIGGSSILKELLRVQQsiGYCPQFDALFEDLTAREHLELYT 147
Cdd:TIGR00955  49 KPGELLAVMGSSGAGKTTlmnalAFRSPKG--VKGSGSVLLNGMPIDAKEMRAIS--AYVQQDDLFIPTLTVREHLMFQA 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  148 RLR---GIPWKDEERVVSWALEKLELSKYADMPAGT------YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPkarrF 218
Cdd:TIGR00955 125 HLRmprRVTKKEKRERVDEVLQALGLRKCANTRIGVpgrvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDS----F 200

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 641957197  219 LWNLILDILK----TGRSVVLTSH--SMEECEaLCTRLGIMVNGRFKCLGSIQHL 267
Cdd:TIGR00955 201 MAYSVVQVLKglaqKGKTIICTIHqpSSELFE-LFDKIILMAEGRVAYLGSPDQA 254
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
 42-250 7.24e-19

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 85.89  E-value: 7.24e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGgssilkellrVQ 121
Cdd:COG0488  313 KKVLELEGLSKSYGDKTL-----LDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLG----------ET 377

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQ-FDALFEDLTAREHLElytrlRGIPWKDEERVVSWaLEKLELS-KYADMPAGTYSGGNKRKLSTAIALIGYP 199
Cdd:COG0488  378 VKIGYFDQhQEELDPDKTVLDELR-----DGAPGGTEQEVRGY-LGRFLFSgDDAFKPVGVLSGGEKARLALAKLLLSPP 451

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 200 SLVFLDEPTTGMDPKARrflwNLILDILKT--GrSVVLTSHSMEECEALCTRL 250
Cdd:COG0488  452 NVLLLDEPTNHLDIETL----EALEEALDDfpG-TVLLVSHDRYFLDRVATRI 499
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
 45-257 8.83e-19

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 80.89  E-value: 8.83e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK---ELLRvq 121
Cdd:cd03228    1 IEFKNVSFSYPGRP---KPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDldlESLR-- 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDlTAREHLelytrlrgipwkdeervvswaleklelskyadmpagtYSGGNKRKLSTAIALIGYPSL 201
Cdd:cd03228   76 KNIAYVPQDPFLFSG-TIRENI-------------------------------------LSGGQRQRIAIARALLRDPPI 117

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 202 VFLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSHSMEECEaLCTRLGIMVNGR 257
Cdd:cd03228  118 LILDEATSALDPETEALILEALRALAK-GKTVIVIAHRLSTIR-DADRIIVLDDGR 171
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
44-257 1.89e-18

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 82.06  E-value: 1.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL--KELLR-V 120
Cdd:PRK09493   1 MIEFKNVSKHF-----GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNdpKVDERlI 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQFDALFEDLTAREHLEL-YTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYP 199
Cdd:PRK09493  76 RQEAGMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKP 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 200 SLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK09493 156 KLMLFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGR 213
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
 45-240 3.05e-18

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 80.65  E-value: 3.05e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL---KELLRVQ 121
Cdd:cd03262    1 IEIKNLHKSFGDFH-----VLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTddkKNINELR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHLEL-YTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:cd03262   76 QKVGMVFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPK 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSM 240
Cdd:cd03262  156 VMLFDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEM 195
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
60-244 3.23e-18

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 84.02  E-value: 3.23e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  60 GRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR--VQQSIGYCPQF--DALFE 135
Cdd:NF033858  12 GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRraVCPRIAYMPQGlgKNLYP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 136 DLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKA 215
Cdd:NF033858  92 TLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLS 171

                        170       180       190
                 ....*....|....*....|....*....|.
gi 641957197 216 RRFLWNLILDILKT--GRSVVLTSHSMEECE 244
Cdd:NF033858 172 RRQFWELIDRIRAErpGMSVLVATAYMEEAE 202
modC_ABC TIGR02142
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ...
 79-271 4.86e-18

molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]


Pssm-ID: 131197 [Multi-domain]  Cd Length: 354  Bit Score: 82.47  E-value: 4.86e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   79 GLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRV-----QQSIGYCPQFDALFEDLTAREHLEL-YTRLRGi 152
Cdd:TIGR02142  27 AIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGIflppeKRRIGYVFQEARLFPHLSVRGNLRYgMKRARP- 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  153 pwkdEERVVSWA--LEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARR----FLWNLILDI 226
Cdd:TIGR02142 106 ----SERRISFErvIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYeilpYLERLHAEF 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 641957197  227 lktGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNRS 271
Cdd:TIGR02142 182 ---GIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAEVWASP 223
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 44-257 7.81e-18

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 82.57  E-value: 7.81e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   44 MLKIDNLTKvyksrKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG--DESTTGGEAFIGGSSILKELLRVQ 121
Cdd:TIGR02633   1 LLEMKGIVK-----TFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGvyPHGTWDGEIYWSGSPLKASNIRDT 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  122 QSIGYC--PQFDALFEDLTAREHLELYTR--LRGIPWKDEERVVSWA--LEKLELSKYAD-MPAGTYSGGNKRKLSTAIA 194
Cdd:TIGR02633  76 ERAGIViiHQELTLVPELSVAENIFLGNEitLPGGRMAYNAMYLRAKnlLRELQLDADNVtRPVGDYGGGQQQLVEIAKA 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197  195 LIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:TIGR02633 156 LNKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQ 218
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
 65-257 1.47e-17

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 78.03  E-value: 1.47e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  65 VDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKELLRVQqsIGYCPQFDALFEDlTARE 141
Cdd:cd03246   18 LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGadiSQWDPNELGDH--VGYLPQDDELFSG-SIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLelytrlrgipwkdeervvswaleklelskyadmpagtYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWN 221
Cdd:cd03246   95 NI-------------------------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQ 137

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 641957197 222 LILDILKTGRSVVLTSHSMEECEAlCTRLGIMVNGR 257
Cdd:cd03246  138 AIAALKAAGATRIVIAHRPETLAS-ADRILVLEDGR 172
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
 64-267 1.90e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 79.89  E-value: 1.90e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---LKELLRVQQSIGYCPQ------FDA-L 133
Cdd:PRK13636  21 ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPIdysRKGLMKLRESVGMVFQdpdnqlFSAsV 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 FEDLTarehlelYTRLR-GIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:PRK13636 101 YQDVS-------FGAVNlKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLD 173

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 213 PKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHL 267
Cdd:PRK13636 174 PMGVSEIMKLLVEMQKeLGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEV 229
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
 45-259 2.02e-17

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 77.74  E-value: 2.02e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGS--SILKELLRvqQ 122
Cdd:cd03247    1 LSINNVSFSYPEQEQ---QVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVpvSDLEKALS--S 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQFDALFeDLTAREHLelytrlrGIPwkdeervvswaleklelskyadmpagtYSGGNKRKLSTAIALIGYPSLV 202
Cdd:cd03247   76 LISVLNQRPYLF-DTTLRNNL-------GRR---------------------------FSGGERQRLALARILLQDAPIV 120

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 203 FLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSHSMEECEALcTRLGIMVNGRFK 259
Cdd:cd03247  121 LLDEPTVGLDPITERQLLSLIFEVLK-DKTLIWITHHLTGIEHM-DKILFLENGKII 175
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
 80-272 3.76e-17

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 79.08  E-value: 3.76e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  80 LLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQSIGYCPQF--DALFEDlTAREHLELYTRLRGIpwkD 156
Cdd:PRK13652  35 VIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIReVRKFVGLVFQNpdDQIFSP-TVEQDIAFGPINLGL---D 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 157 EERV---VSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRS 232
Cdd:PRK13652 111 EETVahrVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPETyGMT 190

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 641957197 233 VVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNRSE 272
Cdd:PRK13652 191 VIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQPD 230
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
50-269 6.72e-17

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 79.69  E-value: 6.72e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  50 LTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK----ELLRVQ-QSI 124
Cdd:PRK10070  29 LSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKisdaELREVRrKKI 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:PRK10070 109 AMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLM 188

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 205 DEPTTGMDPKARRFLWNLILDI-LKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:PRK10070 189 DEAFSALDPLIRTEMQDELVKLqAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILN 254
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
 64-239 8.03e-17

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 79.71  E-value: 8.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK----ELLRVqqsIGYCPQFDALFeDLTA 139
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSldqdEVRRR---VSVCAQDAHLF-DTTV 425

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  140 REHLELytrlrGIPWKDEERVvSWALEKLELSKY-ADMPAG----------TYSGGNKRKLSTAIALIGYPSLVFLDEPT 208
Cdd:TIGR02868 426 RENLRL-----ARPDATDEEL-WAALERVGLADWlRALPDGldtvlgeggaRLSGGERQRLALARALLADAPILLLDEPT 499

                         170       180       190
                  ....*....|....*....|....*....|.
gi 641957197  209 TGMDPKARRFLWNLILDILkTGRSVVLTSHS 239
Cdd:TIGR02868 500 EHLDAETADELLEDLLAAL-SGRTVVLITHH 529
nickel_nikE TIGR02769
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ...
 44-257 9.28e-17

nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131816 [Multi-domain]  Cd Length: 265  Bit Score: 77.54  E-value: 9.28e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   44 MLKIDNLTKVYKS----RKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKelLR 119
Cdd:TIGR02769   2 LLEVRDVTHTYRTgglfGAKQRAPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQ--LD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  120 VQQSIGYCPQFDALFED--------LTAR----EHLELYTRLRGipwKDEERVVSWALEKLEL-SKYADMPAGTYSGGNK 186
Cdd:TIGR02769  80 RKQRRAFRRDVQLVFQDspsavnprMTVRqiigEPLRHLTSLDE---SEQKARIAELLDMVGLrSEDADKLPRQLSGGQL 156

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197  187 RKLSTAIALIGYPSLVFLDEPTTGMDpkarRFLWNLILDILKT-----GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:TIGR02769 157 QRINIARALAVKPKLIVLDEAVSNLD----MVLQAVILELLRKlqqafGTAYLFITHDLRLVQSFCQRVAVMDKGQ 228
CydD COG4988
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ...
 40-241 1.15e-16

ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444012 [Multi-domain]  Cd Length: 563  Bit Score: 79.42  E-value: 1.15e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  40 ADNDMLKIDNLTKVYKSRKmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKE 116
Cdd:COG4988  332 AGPPSIELEDVSFSYPGGR----PALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGvdlSDLDPA 407

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 LLRvqQSIGYCPQFDALFEDlTAREHLELYTrlrgiPWKDEERVVSwALEKLELSKY-ADMPAG----------TYSGGN 185
Cdd:COG4988  408 SWR--RQIAWVPQNPYLFAG-TIRENLRLGR-----PDASDEELEA-ALEAAGLDEFvAALPDGldtplgeggrGLSGGQ 478

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSHSME 241
Cdd:COG4988  479 AQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLAK-GRTVILITHRLA 533
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
 67-238 2.33e-16

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 75.22  E-value: 2.33e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  67 RLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSIGYCPQFDALFEDLTAREHLELY 146
Cdd:cd03231   18 GLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLGHAPGIKTTLSVLENLRFW 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 147 TRLRGipwkDEErvVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI 226
Cdd:cd03231   98 HADHS----DEQ--VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGH 171

                        170
                 ....*....|..
gi 641957197 227 LKTGRSVVLTSH 238
Cdd:cd03231  172 CARGGMVVLTTH 183
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
42-217 3.19e-16

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 77.45  E-value: 3.19e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKvyksrKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRvQ 121
Cdd:PRK11432   4 KNFVVLKNITK-----RFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVTHRSIQ-Q 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHLELYTRLRGIPwKDEERV-VSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:PRK11432  78 RDICMVFQSYALFPHMSLGENVGYGLKMLGVP-KEERKQrVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPK 156

                        170
                 ....*....|....*..
gi 641957197 201 LVFLDEPTTGMDPKARR 217
Cdd:PRK11432 157 VLLFDEPLSNLDANLRR 173
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
 41-257 3.52e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 76.18  E-value: 3.52e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  41 DNDMLKIDNLTKVYKSRKMgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR- 119
Cdd:PRK13632   4 KSVMIKVENVSFSYPNSEN---NALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITISKENLKe 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQF-DALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:PRK13632  81 IRKKIGIIFQNpDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALN 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLT-SHSMEECeALCTRLGIMVNGR 257
Cdd:PRK13632 161 PEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISiTHDMDEA-ILADKVIVFSEGK 219
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
 17-241 4.66e-16

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 77.33  E-value: 4.66e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   17 SSQPIEDDDEDVASERRRVlrGEADNDMLKIDNLTKVYKsrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLT 96
Cdd:TIGR02857 296 ALFAVLDAAPRPLAGKAPV--TAAPASSLEFSGVSVAYP----GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLL 369

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   97 GDESTTGGEAFIGGSSiLKELLR--VQQSIGYCPQFDALFEDlTAREHLELYTrlrgiPWKDEERVVSwALEKLELSKY- 173
Cdd:TIGR02857 370 GFVDPTEGSIAVNGVP-LADADAdsWRDQIAWVPQHPFLFAG-TIAENIRLAR-----PDASDAEIRE-ALERAGLDEFv 441

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  174 ADMPAGTY----------SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARrflwNLILDILK---TGRSVVLTSHSM 240
Cdd:TIGR02857 442 AALPQGLDtpigeggaglSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETE----AEVLEALRalaQGRTVLLVTHRL 517


                  .
gi 641957197  241 E 241
Cdd:TIGR02857 518 A 518
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
75-256 4.93e-16

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 75.69  E-value: 4.93e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  75 GECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLrvQQSIGYCPQ-------FDALFEDLTAREHLELYT 147
Cdd:PRK15056  33 GSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQ--KNLVAYVPQseevdwsFPVLVEDVVMMGRYGHMG 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 148 RLRgIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIL 227
Cdd:PRK15056 111 WLR-RAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELR 189

                        170       180
                 ....*....|....*....|....*....
gi 641957197 228 KTGRSVVLTSHSMEECEALCTrLGIMVNG 256
Cdd:PRK15056 190 DEGKTMLVSTHNLGSVTEFCD-YTVMVKG 217
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
42-257 1.59e-15

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 73.76  E-value: 1.59e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK-ELLRV 120
Cdd:PRK11614   3 KVMLSFDKVSAHY-----GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDwQTAKI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 -QQSIGYCPQFDALFEDLTAREHLELytrlrGIPWKDEERV---VSWALEKL-ELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:PRK11614  78 mREAVAIVPEGRRVFSRMTVEENLAM-----GGFFAERDQFqerIKWVYELFpRLHERRIQRAGTMSGGEQQMLAIGRAL 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK11614 153 MSQPRLLLLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGH 214
ntrCD TIGR01184
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ...
 70-264 1.88e-15

nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]


Pssm-ID: 130252 [Multi-domain]  Cd Length: 230  Bit Score: 73.65  E-value: 1.88e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK---ELLRVQQSIgycpqfdALFEDLTAREHLELY 146
Cdd:TIGR01184   6 LTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEpgpDRMVVFQNY-------SLLPWLTVRENIALA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  147 TR--LRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLIL 224
Cdd:TIGR01184  79 VDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELM 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 641957197  225 DILKTGR-SVVLTSHSMEECEALCTRLGIMVNGRFKCLGSI 264
Cdd:TIGR01184 159 QIWEEHRvTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQI 199
COG4559 COG4559
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
44-218 1.91e-15

ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443620 [Multi-domain]  Cd Length: 258  Bit Score: 74.00  E-value: 1.91e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRkmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----LKELLR 119
Cdd:COG4559    1 MLEAENLSVRLGGR---TLL--DDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLaawsPWELAR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 V-----QQSigycpqfdALFEDLTAREHLelytRLRGIPW----KDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLS 190
Cdd:COG4559   76 RravlpQHS--------SLAFPFTVEEVV----ALGRAPHgssaAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQ 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 641957197 191 TAIALI-------GYPSLVFLDEPTTGMDPK--------ARRF 218
Cdd:COG4559  144 LARVLAqlwepvdGGPRWLFLDEPTSALDLAhqhavlrlARQL 186
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
44-269 1.96e-15

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 73.89  E-value: 1.96e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMgrILAVDrlcLGVRPGECFGLLGVNGAGKTTTFK----MLTGDESTTGGEAFIGGS-----SIL 114
Cdd:PRK09984   4 IIRVEKLAKTFNQHQA--LHAVD---LNIHHGEMVALLGPSGSGKSTLLRhlsgLITGDKSAGSHIELLGRTvqregRLA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 115 KELLRVQQSIGYCPQFDALFEDLTAREHLeLYTRLRGIP-WKDeerVVSW-----------ALEKLELSKYADMPAGTYS 182
Cdd:PRK09984  79 RDIRKSRANTGYIFQQFNLVNRLSVLENV-LIGALGSTPfWRT---CFSWftreqkqralqALTRVGMVHFAHQRVSTLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 183 GGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCL 261
Cdd:PRK09984 155 GGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVALRQGHVFYD 234


                 ....*...
gi 641957197 262 GSIQHLKN 269
Cdd:PRK09984 235 GSSQQFDN 242
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
44-240 2.02e-15

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 73.37  E-value: 2.02e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK----ELLR 119
Cdd:PRK10908   1 MIRFEHVSKAY----LGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlknrEVPF 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYP 199
Cdd:PRK10908  77 LRRQIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKP 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 641957197 200 SLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSM 240
Cdd:PRK10908 157 AVLLADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDI 197
cbiO PRK13650
energy-coupling factor transporter ATPase;
43-272 2.45e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 74.00  E-value: 2.45e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  43 DMLKIDNLTKVYKSRKMGRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKE-LLRVQ 121
Cdd:PRK13650   3 NIIEVKNLTFKYKEDQEKYTL--NDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEEnVWDIR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQF-DALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:PRK13650  81 HKIGMVFQNpDNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPK 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECeALCTRLGIMVNGRFKCLGSIQHLKNRSE 272
Cdd:PRK13650 161 IIILDEATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFSRGN 232
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
45-263 3.61e-15

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 74.21  E-value: 3.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL------KELL 118
Cdd:PRK09452  15 VELRGISKSFDGKE-----VISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDIThvpaenRHVN 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 119 RVQQSigYcpqfdALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:PRK09452  90 TVFQS--Y-----ALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNK 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLiLDIL--KTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:PRK09452 163 PKVLLLDESLSALDYKLRKQMQNE-LKALqrKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGT 228
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 26-258 3.90e-15

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 74.68  E-value: 3.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  26 EDVASERRRVlRGEADNDMLKIDNLTkVYKSRKmgrILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGE 105
Cdd:COG3845  240 REVLLRVEKA-PAEPGEVVLEVENLS-VRDDRG---VPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGS 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 106 AFIGGSSILKE--LLRVQQSIGYCP---QFDALFEDLTAREHLELyTRLRGIP-----WKDEERVVSWALEKLElsKY-- 173
Cdd:COG3845  315 IRLDGEDITGLspRERRRLGVAYIPedrLGRGLVPDMSVAENLIL-GRYRRPPfsrggFLDRKAIRAFAEELIE--EFdv 391

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 174 ----ADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTR 249
Cdd:COG3845  392 rtpgPDTPARSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDR 471


                 ....*....
gi 641957197 250 LGIMVNGRF 258
Cdd:COG3845  472 IAVMYEGRI 480
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
68-241 4.84e-15

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 73.12  E-value: 4.84e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  68 LCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---LKELLRVQQSIGYC---PQFDALFEDLTARE 141
Cdd:PRK13638  20 LNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLdysKRGLLALRQQVATVfqdPEQQIFYTDIDSDI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLELytRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWN 221
Cdd:PRK13638 100 AFSL--RNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIA 177

                        170       180
                 ....*....|....*....|
gi 641957197 222 LILDILKTGRSVVLTSHSME 241
Cdd:PRK13638 178 IIRRIVAQGNHVIISSHDID 197
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
45-258 5.14e-15

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 74.18  E-value: 5.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---------SSILK 115
Cdd:PRK11288   5 LSFDGIGKTFPGVK-----ALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGqemrfasttAALAA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLRVQQSIGYCPqfdalfeDLTAREHL---ELYTRLrgiPWKDEERVVSWALEKLE---LSKYADMPAGTYSGGNKRKL 189
Cdd:PRK11288  80 GVAIIYQELHLVP-------EMTVAENLylgQLPHKG---GIVNRRLLNYEAREQLEhlgVDIDPDTPLKYLSIGQRQMV 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:PRK11288 150 EIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEGRVILYVSHRMEEIFALCDAITVFKDGRY 218
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
44-212 7.14e-15

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 71.77  E-value: 7.14e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMGRILAVDrLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG------SSILKEL 117
Cdd:PRK11629   5 LLQCDNLCKRYQEGSVQTDVLHN-VSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGqpmsklSSAAKAE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 118 LRVQQsIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIG 197
Cdd:PRK11629  84 LRNQK-LGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVN 162

                        170
                 ....*....|....*
gi 641957197 198 YPSLVFLDEPTTGMD 212
Cdd:PRK11629 163 NPRLVLADEPTGNLD 177
cbiO PRK13645
energy-coupling factor transporter ATPase;
47-263 7.32e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 72.73  E-value: 7.32e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI------LKELLRV 120
Cdd:PRK13645   9 LDNVSYTYAKKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIpanlkkIKEVKRL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQFD--ALFEDLTARE------HLElytrlrgipwKDEERVVSWALEKLEL----SKYADMPAGTYSGGNKRK 188
Cdd:PRK13645  89 RKEIGLVFQFPeyQLFQETIEKDiafgpvNLG----------ENKQEAYKKVPELLKLvqlpEDYVKRSPFELSGGQKRR 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 189 LSTA--IALIGypSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:PRK13645 159 VALAgiIAMDG--NTLVLDEPTGGLDPKGEEDFINLFERLNKEyKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGS 234
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
 77-239 7.46e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 72.18  E-value: 7.46e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  77 CFGLLGVNGAGKTT---TFKMLT--GDESTTGGEAFIGGSSILKE---LLRVQQSIGYCPQFDALFEDLTAREHLELYTR 148
Cdd:PRK14267  32 VFALMGPSGCGKSTllrTFNRLLelNEEARVEGEVRLFGRNIYSPdvdPIEVRREVGMVFQYPNPFPHLTIYDNVAIGVK 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 149 LRGI--PWKDEERVVSWALEKLEL-----SKYADMPaGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWN 221
Cdd:PRK14267 112 LNGLvkSKKELDERVEWALKKAALwdevkDRLNDYP-SNLSGGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEE 190

                        170
                 ....*....|....*...
gi 641957197 222 LILDiLKTGRSVVLTSHS 239
Cdd:PRK14267 191 LLFE-LKKEYTIVLVTHS 207
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
 60-238 8.41e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 71.87  E-value: 8.41e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  60 GRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG-----DESTTGGEAFIGGSSILK----ELLRVQQSIGYCPQf 130
Cdd:PRK14247  14 GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRlielyPEARVSGEVYLDGQDIFKmdviELRRRVQMVFQIPN- 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 131 daLFEDLTAREHLELYTRL-RGIPWKDE-ERVVSWALEKLEL----SKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFL 204
Cdd:PRK14247  93 --PIPNLSIFENVALGLKLnRLVKSKKElQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLA 170

                        170       180       190
                 ....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDiLKTGRSVVLTSH 238
Cdd:PRK14247 171 DEPTANLDPENTAKIESLFLE-LKKDMTIVLVTH 203
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
 70-259 8.80e-15

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 71.73  E-value: 8.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQ---QSIGYCPQFDALFEDLTAREHLE 144
Cdd:PRK10584  31 LVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLhqMDEEARAKlraKHVGFVFQSFMLIPTLNALENVE 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 145 LYTRLRGIPWKDEERVVSWALEKLELSKYAD-MPAgTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLI 223
Cdd:PRK10584 111 LPALLRGESSRQSRNGAKALLEQLGLGKRLDhLPA-QLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLL 189

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 641957197 224 LDILKT-GRSVVLTSHSmEECEALCTRLGIMVNGRFK 259
Cdd:PRK10584 190 FSLNREhGTTLILVTHD-LQLAARCDRRLRLVNGQLQ 225
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
 45-238 1.13e-14

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 69.40  E-value: 1.13e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKmgrILAVDRLclGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSsilkellrvqQSI 124
Cdd:cd03221    1 IELENLSKTYGGKL---LLKDISL--TINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGST----------VKI 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFdalfedltarehlelytrlrgipwkdeervvswaleklelskyadmpagtySGGNKRKLSTAIALIGYPSLVFL 204
Cdd:cd03221   66 GYFEQL---------------------------------------------------SGGEKMRLALAKLLLENPNLLLL 94

                        170       180       190
                 ....*....|....*....|....*....|....
gi 641957197 205 DEPTTGMDPKARRFLWNLILDilkTGRSVVLTSH 238
Cdd:cd03221   95 DEPTNHLDLESIEALEEALKE---YPGTVILVSH 125
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
 41-241 1.33e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 72.19  E-value: 1.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  41 DNDMLKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTT---FKML--------------TGDESTTG 103
Cdd:PRK13631  18 DDIILRVKNLYCVFDEKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLvthFNGLikskygtiqvgdiyIGDKKNNH 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 104 GEAFIGGSSILKELLRVQQSIGYCPQFD--ALFEDlTAREHLELYTRLRGIPWKDEERVVSWALEKLEL-SKYADMPAGT 180
Cdd:PRK13631  98 ELITNPYSKKIKNFKELRRRVSMVFQFPeyQLFKD-TIEKDIMFGPVALGVKKSEAKKLAKFYLNKMGLdDSYLERSPFG 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 181 YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:PRK13631 177 LSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTME 237
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
 72-256 2.66e-14

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 72.39  E-value: 2.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKELLRVQQSIGYCPQFDALFEDLTAREHLelytrL 149
Cdd:PRK15439  34 LHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCarLTPAKAHQLGIYLVPQEPLLFPNLSVKENI-----L 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 150 RGIPWK-DEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK 228
Cdd:PRK15439 109 FGLPKRqASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTASLTPAETERLFSRIRELLA 188

                        170       180
                 ....*....|....*....|....*...
gi 641957197 229 TGRSVVLTSHSMEECEALCTRLGIMVNG 256
Cdd:PRK15439 189 QGVGIVFISHKLPEIRQLADRISVMRDG 216
PhnK COG1101
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
 44-257 2.91e-14

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 440718 [Multi-domain]  Cd Length: 264  Bit Score: 70.50  E-value: 2.91e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKE----- 116
Cdd:COG1101    1 MLELKNLSKTFNPGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVtkLPEykrak 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 -LLRVQQ--SIGYCPqfdalfeDLTAREHLEL-YTR------LRGIPWKDEERVVSwALEKLELS--KYADMPAGTYSGG 184
Cdd:COG1101   81 yIGRVFQdpMMGTAP-------SMTIEENLALaYRRgkrrglRRGLTKKRRELFRE-LLATLGLGleNRLDTKVGLLSGG 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 185 NKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRsvvLTS----HSMEECEALCTRLGIMVNGR 257
Cdd:COG1101  153 QRQALSLLMATLTKPKLLLLDEHTAALDPKTAALVLELTEKIVEENN---LTTlmvtHNMEQALDYGNRLIMMHEGR 226
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
 44-218 3.30e-14

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 70.57  E-value: 3.30e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRkmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----LKELLR 119
Cdd:PRK13548   2 MLEARNLSVRLGGR---TLL--DDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLadwsPAELAR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 vqqSIGYCPQFDALFEDLTAREhlelYTRLRGIPW----KDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:PRK13548  77 ---RRAVLPQHSSLSFPFTVEE----VVAMGRAPHglsrAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVL 149

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 641957197 196 I------GYPSLVFLDEPTTGMDPK--------ARRF 218
Cdd:PRK13548 150 AqlwepdGPPRWLLLDEPTSALDLAhqhhvlrlARQL 186
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
 44-257 4.68e-14

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 71.60  E-value: 4.68e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSsilkellRVQQS 123
Cdd:COG3845    5 ALELRGITKRF-----GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGK-------PVRIR 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 ---------IGYCPQ-FdALFEDLTAREHLELY---TRLRGIPWKDEERVVSWALEKLELS-----KYADMPAGTysggn 185
Cdd:COG3845   73 sprdaialgIGMVHQhF-MLVPNLTVAENIVLGlepTKGGRLDRKAARARIRELSERYGLDvdpdaKVEDLSVGE----- 146

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLwnliLDILKT----GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG3845  147 QQRVEILKALYRGARILILDEPTAVLTPQEADEL----FEILRRlaaeGKSIIFITHKLREVMAIADRVTVLRRGK 218
cbiO PRK13641
energy-coupling factor transporter ATPase;
45-242 6.68e-14

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 69.86  E-value: 6.68e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL-----KELLR 119
Cdd:PRK13641   3 IKFENVDYIYSPGTPMEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITpetgnKNLKK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQF--DALFEDlTAREHLELYTRLRGIPWKD-EERVVSWaLEKLELSK-YADMPAGTYSGGNKRKLSTAIAL 195
Cdd:PRK13641  83 LRKKVSLVFQFpeAQLFEN-TVLKDVEFGPKNFGFSEDEaKEKALKW-LKKVGLSEdLISKSPFELSGGQMRRVAIAGVM 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEE 242
Cdd:PRK13641 161 AYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDD 207
PLN03211 PLN03211
ABC transporter G-25; Provisional
 74-238 8.66e-14

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 71.06  E-value: 8.66e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  74 PGECFGLLGVNGAGKTTTFKMLTGDESTTG--GEAFIGGSSILKELLRvqqSIGYCPQFDALFEDLTAREHLELYTRLR- 150
Cdd:PLN03211  93 PGEILAVLGPSGSGKSTLLNALAGRIQGNNftGTILANNRKPTKQILK---RTGFVTQDDILYPHLTVRETLVFCSLLRl 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 151 --GIPWKDEERVVSWALEKLELSKYADMPAGT-----YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLI 223
Cdd:PLN03211 170 pkSLTKQEKILVAESVISELGLTKCENTIIGNsfirgISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTL 249

                        170
                 ....*....|....*
gi 641957197 224 LDILKTGRSVVLTSH 238
Cdd:PLN03211 250 GSLAQKGKTIVTSMH 264
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
 39-246 1.03e-13

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 69.39  E-value: 1.03e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  39 EADNDMLKIDNLTKVYKSRKMgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----L 114
Cdd:PRK13648   2 EDKNSIIVFKNVSFQYQSDAS---FTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAItddnF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 115 KELLR---------VQQSIGYCPQFDALFedltareHLELYTrlrgIPWKDEERVVSWALEKLELSKYADMPAGTYSGGN 185
Cdd:PRK13648  79 EKLRKhigivfqnpDNQFVGSIVKYDVAF-------GLENHA----VPYDEMHRRVSEALKQVDMLERADYEPNALSGGQ 147

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDiLKTGRSVVLTSHSMEECEAL 246
Cdd:PRK13648 148 KQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRK-VKSEHNITIISITHDLSEAM 207
cbiO PRK13646
energy-coupling factor transporter ATPase;
45-256 1.30e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 69.04  E-value: 1.30e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL-----KELLR 119
Cdd:PRK13646   3 IRFDNVSYTYQKGTPYEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITIThktkdKYIRP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQF--DALFEDLTAREhLELYTRLRGIpwkDEERVVSWALEKL-ELSKYAD-MPAGTY--SGGNKRKLSTAI 193
Cdd:PRK13646  83 VRKRIGMVFQFpeSQLFEDTVERE-IIFGPKNFKM---NLDEVKNYAHRLLmDLGFSRDvMSQSPFqmSGGQMRKIAIVS 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 194 ALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI-LKTGRSVVLTSHSMEECEALCTRLGIMVNG 256
Cdd:PRK13646 159 ILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLqTDENKTIILVSHDMNEVARYADEVIVMKEG 222
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
 39-267 1.77e-13

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 69.85  E-value: 1.77e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  39 EADNDMLKIDNLTKVYKSRKMgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK--- 115
Cdd:PRK11160 333 AADQVSLTLNNVSFTYPDQPQ---PVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADyse 409

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLRvqQSIGYCPQFDALFEDlTAREHLELytrlrGIPWKDEERVVSwALEKLELSKYADMPAG----------TYSGGN 185
Cdd:PRK11160 410 AALR--QAISVVSQRVHLFSA-TLRDNLLL-----AAPNASDEALIE-VLQQVGLEKLLEDDKGlnawlgeggrQLSGGE 480

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSH---SMEECEALCtrlgIMVNGRFKCLG 262
Cdd:PRK11160 481 QRRLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHAQ-NKTVLMITHrltGLEQFDRIC----VMDNGQIIEQG 555


                 ....*
gi 641957197 263 SIQHL 267
Cdd:PRK11160 556 THQEL 560
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 44-247 2.00e-13

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 69.57  E-value: 2.00e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKvyksrKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG--DESTTGGEAFIGGSSI----LKEL 117
Cdd:PRK13549   5 LLEMKNITK-----TFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGvyPHGTYEGEIIFEGEELqasnIRDT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 118 LRVQQSIGYcpQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWA---LEKLELSKYADMPAGTYSGGNKRKLSTAIA 194
Cdd:PRK13549  80 ERAGIAIIH--QELALVKELSVLENIFLGNEITPGGIMDYDAMYLRAqklLAQLKLDINPATPVGNLGLGQQQLVEIAKA 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 641957197 195 LIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALC 247
Cdd:PRK13549 158 LNKQARLLILDEPTASLTESETAVLLDIIRDLKAHGIACIYISHKLNEVKAIS 210
cbiO PRK13649
energy-coupling factor transporter ATPase;
70-257 2.10e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 68.62  E-value: 2.10e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL-----KELLRVQQSIGYCPQF--DALFEDlTAREH 142
Cdd:PRK13649  28 LTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITstsknKDIKQIRKKVGLVFQFpeSQLFEE-TVLKD 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 143 LELYTRLRGIPWKDEERVvswALEKLEL----SKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRF 218
Cdd:PRK13649 107 VAFGPQNFGVSQEEAEAL---AREKLALvgisESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKGRKE 183

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 641957197 219 LWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK13649 184 LMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGK 222
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
 41-257 2.42e-13

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 68.03  E-value: 2.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  41 DNDMLKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEA-FIGGSSILKELLR 119
Cdd:PRK11701   3 DQPLLSVRGLTKLY-----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVhYRMRDGQLRDLYA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSI---------GYCPQF--DALFEDLTAREHL-ElytRLRGIPWKD----EERVVSWaLEKLEL--SKYADMPAgTY 181
Cdd:PRK11701  78 LSEAErrrllrtewGFVHQHprDGLRMQVSAGGNIgE---RLMAVGARHygdiRATAGDW-LERVEIdaARIDDLPT-TF 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 182 SGGNKRKLSTAIALIGYPSLVFLDEPTTGMD--PKARrflwnlILDILKT-----GRSVVLTSHSMEECEALCTRLGIMV 254
Cdd:PRK11701 153 SGGMQQRLQIARNLVTHPRLVFMDEPTGGLDvsVQAR------LLDLLRGlvrelGLAVVIVTHDLAVARLLAHRLLVMK 226


                 ...
gi 641957197 255 NGR 257
Cdd:PRK11701 227 QGR 229
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
 39-259 2.70e-13

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 69.47  E-value: 2.70e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   39 EADNDMLKIDNLTKVYKSRKmgRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGD-ESTTGGEAFIGGS--SILK 115
Cdd:TIGR02633 252 EIGDVILEARNLTCWDVINP--HRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAyPGKFEGNVFINGKpvDIRN 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  116 ELLRVQQSIGYCPQ---FDALFEDLTAREHLEL-----YTRLRGIPWKDEERVVSWALEKLELSKYA-DMPAGTYSGGNK 186
Cdd:TIGR02633 330 PAQAIRAGIAMVPEdrkRHGIVPILGVGKNITLsvlksFCFKMRIDAAAELQIIGSAIQRLKVKTASpFLPIGRLSGGNQ 409

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197  187 RKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFK 259
Cdd:TIGR02633 410 QKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLK 482
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
 45-257 2.95e-13

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 67.78  E-value: 2.95e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRkmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEaFIGGSSILKEllrvqqsi 124
Cdd:PRK11247  13 LLLNAVSKRYGER---TVL--NQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGE-LLAGTAPLAE-------- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 gycpqfdalfedltAREHlelyTRL-----RGIPWKdeeRVV---------SW---ALEKLE---LSKYA-DMPAgTYSG 183
Cdd:PRK11247  79 --------------ARED----TRLmfqdaRLLPWK---KVIdnvglglkgQWrdaALQALAavgLADRAnEWPA-ALSG 136

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 184 GNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI-LKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK11247 137 GQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGK 211
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
 10-257 3.05e-13

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 69.11  E-value: 3.05e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  10 YNRRVPVSSQPIEDDDEDVAsERRRVLRGEAdndMLKIDNLTKVYKSRK--MGRIL----AVDRLCLGVRPGECFGLLGV 83
Cdd:PRK10261 283 YPRRFPLISLEHPAKQEPPI-EQDTVVDGEP---ILQVRNLVTRFPLRSglLNRVTrevhAVEKVSFDLWPGETLSLVGE 358

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  84 NGAGKTTTFKMLTGDESTTGGEAFIGGSSI-------LKELLRVQQSIgycpqFDALFEDLTAR--------EHLELYTR 148
Cdd:PRK10261 359 SGSGKSTTGRALLRLVESQGGEIIFNGQRIdtlspgkLQALRRDIQFI-----FQDPYASLDPRqtvgdsimEPLRVHGL 433

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 149 LRGipwKDEERVVSWALEKLEL-SKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIL 227
Cdd:PRK10261 434 LPG---KAAAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQ 510

                        250       260       270
                 ....*....|....*....|....*....|.
gi 641957197 228 KT-GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK10261 511 RDfGIAYLFISHDMAVVERISHRVAVMYLGQ 541
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
45-265 3.80e-13

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 68.19  E-value: 3.80e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQsI 124
Cdd:PRK10851   3 IEIANIKKSF-----GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRK-V 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDLTAREHLELytRLRGIPWKDE------ERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:PRK10851  77 GFVFQHYALFRHMTVFDNIAF--GLTVLPRRERpnaaaiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVE 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 199 PSLVFLDEPTTGMDPKA----RRFLWNLILDILKTGrsvVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQ 265
Cdd:PRK10851 155 PQILLLDEPFGALDAQVrkelRRWLRQLHEELKFTS---VFVTHDQEEAMEVADRVVVMSQGNIEQAGTPD 222
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
 44-238 3.98e-13

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 66.51  E-value: 3.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRkmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQS 123
Cdd:PRK13540   1 MLDVIELDFDYHDQ-----PLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSIKKDLCTYQKQ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTAREH--LELYTRLRGIPWKDEERVVSwalekleLSKYADMPAGTYSGGNKRKLSTAIALIGYPSL 201
Cdd:PRK13540  76 LCFVGHRSGINPYLTLRENclYDIHFSPGAVGITELCRLFS-------LEHLIDYPCGLLSSGQKRQVALLRLWMSKAKL 148

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 641957197 202 VFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:PRK13540 149 WLLDEPLVALDELSLLTIITKIQEHRAKGGAVLLTSH 185
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 44-258 4.48e-13

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 68.49  E-value: 4.48e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGE-AFIGGSSILKELLRVQQ 122
Cdd:PRK10762   4 LLQLKGIDKAFPGVK-----ALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSiLYLGKEVTFNGPKSSQE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 S-IGYCPQFDALFEDLTAREHL----ELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIG 197
Cdd:PRK10762  79 AgIGIIHQELNLIPQLTIAENIflgrEFVNRFGRIDWKKMYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSF 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 198 YPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:PRK10762 159 ESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRLKEIFEICDDVTVFRDGQF 219
YnjD COG4136
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ...
 44-245 5.74e-13

ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];


Pssm-ID: 443311 [Multi-domain]  Cd Length: 211  Bit Score: 65.97  E-value: 5.74e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDES---TTGGEAFIGGSSILKelLRV 120
Cdd:COG4136    1 MLSLENLTITLGGRPL-----LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSpafSASGEVLLNGRRLTA--LPA 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQ-SIGYCPQFDALFEDLTAREHLELYTRlRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYP 199
Cdd:COG4136   74 EQrRIGILFQDDLLFPHLSVGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEP 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 641957197 200 SLVFLDEPTTGMDP----KARRFLWNLILDilkTGRSVVLTSHSMEECEA 245
Cdd:COG4136  153 RALLLDEPFSKLDAalraQFREFVFEQIRQ---RGIPALLVTHDEEDAPA 199
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
54-257 6.62e-13

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 68.01  E-value: 6.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  54 YKSRKMGRI-LAVDRL---------CLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR--VQ 121
Cdd:PRK11288 248 YRPRPLGEVrLRLDGLkgpglrepiSFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRdaIR 327

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQ---FDALFEDLTAREHLELYTRLRGIPW------KDEERVVSWALEKLEL-SKYADMPAGTYSGGNKRK--- 188
Cdd:PRK11288 328 AGIMLCPEdrkAEGIIPVHSVADNINISARRHHLRAgclinnRWEAENADRFIRSLNIkTPSREQLIMNLSGGNQQKail 407

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 189 ---LSTAIALIgypslvFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK11288 408 grwLSEDMKVI------LLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGR 473
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
 63-240 7.41e-13

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 66.36  E-value: 7.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  63 LAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKELLRVQqsIGYCPQFDALFeDLTA 139
Cdd:cd03252   16 VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGhdlALADPAWLRRQ--VGVVLQENVLF-NRSI 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 140 REHLELytrlrGIPWKDEERVVswaleklELSKYAD-------MPAG----------TYSGGNKRKLSTAIALIGYPSLV 202
Cdd:cd03252   93 RDNIAL-----ADPGMSMERVI-------EAAKLAGahdfiseLPEGydtivgeqgaGLSGGQRQRIAIARALIHNPRIL 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 641957197 203 FLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSHSM 240
Cdd:cd03252  161 IFDEATSALDYESEHAIMRNMHDICA-GRTVIIIAHRL 197
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
 45-257 8.52e-13

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 65.57  E-value: 8.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGssilkellrvqqSI 124
Cdd:cd03250    1 ISVEDASFTWDSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG------------SI 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCPQFDALFEDlTAREHLelytrLRGIPWkDEER----VVSWALEK-LELskyadMPAG----------TYSGGNKRKL 189
Cdd:cd03250   69 AYVSQEPWIQNG-TIRENI-----LFGKPF-DEERyekvIKACALEPdLEI-----LPDGdlteigekgiNLSGGQKQRI 136

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLW-NLILDILKTGRSVVLTSHSMEECEAlCTRLGIMVNGR 257
Cdd:cd03250  137 SLARAVYSDADIYLLDDPLSAVDAHVGRHIFeNCILGLLLNNKTRILVTHQLQLLPH-ADQIVVLDNGR 204
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
 75-269 9.11e-13

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 66.19  E-value: 9.11e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  75 GECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI-------LKELLRVQQSIGYCPQFDALFEDLTAREHL-ELY 146
Cdd:PRK11124  28 GETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsktpsDKAIRELRRNVGMVFQQYNLWPHLTVQQNLiEAP 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 147 TRLRGIpwkDEERVVSWA---LEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLI 223
Cdd:PRK11124 108 CRVLGL---SKDQALARAeklLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSII 184

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 641957197 224 LDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:PRK11124 185 RELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTQ 230
cbiO PRK13644
energy-coupling factor transporter ATPase;
44-263 9.24e-13

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 66.55  E-value: 9.24e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG--SSILKELLRVQ 121
Cdd:PRK13644   1 MIRLENVSYSYPDGTP----ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGidTGDFSKLQGIR 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQF-DALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:PRK13644  77 KLVGIVFQNpETQFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEPE 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEAlCTRLGIMVNGRFKCLGS 263
Cdd:PRK13644 157 CLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEELHD-ADRIIVMDRGKIVLEGE 218
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
 42-270 1.28e-12

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 66.30  E-value: 1.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRKMgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-V 120
Cdd:PRK13647   2 DNIIEVEDLHFRYKDGTK----ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKwV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQF--DALFEDlTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:PRK13647  78 RSKVGLVFQDpdDQVFSS-TVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMD 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNlILDIL-KTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNR 270
Cdd:PRK13647 157 PDVIVLDEPMAYLDPRGQETLME-ILDRLhNQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDE 228
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
 45-257 1.33e-12

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 65.21  E-value: 1.33e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILAVDRlclgvrpGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGssilkellrvqQSI 124
Cdd:cd03298    1 VRLDKIRFSYGEQPMHFDLTFAQ-------GEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLING-----------VDV 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 125 GYCP----------QFDALFEDLTAREH--LELYTRLRGIPwKDEERVVSwALEKLELSKYADMPAGTYSGGNKRKLSTA 192
Cdd:cd03298   63 TAAPpadrpvsmlfQENNLFAHLTVEQNvgLGLSPGLKLTA-EDRQAIEV-ALARVGLAGLEKRLPGELSGGERQRVALA 140

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 193 IALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:cd03298  141 RVLVRDKPVLLLDEPFAALDPALRAEMLDLVLDLHAeTKMTVLMVTHQPEDAKRLAQRVVFLDNGR 206
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
74-257 1.56e-12

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 65.42  E-value: 1.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  74 PGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI-------LKELLRVQQSIGYCPQFDALFEDLTAREHL-EL 145
Cdd:COG4161   27 SGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsqkpsEKAIRLLRQKVGMVFQQYNLWPHLTVMENLiEA 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 146 YTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILD 225
Cdd:COG4161  107 PCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRE 186

                        170       180       190
                 ....*....|....*....|....*....|..
gi 641957197 226 ILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:COG4161  187 LSQTGITQVIVTHEVEFARKVASQVVYMEKGR 218
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
 44-240 1.81e-12

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 65.54  E-value: 1.81e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMgrILAVDrlcLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--------LK 115
Cdd:PRK11264   3 AIEVKNLVKKFHGQTV--LHGID---LEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIdtarslsqQK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLR-VQQSIGYCPQFDALFEDLTAREH-LELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAI 193
Cdd:PRK11264  78 GLIRqLRQHVGFVFQNFNLFPHRTVLENiIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIAR 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 641957197 194 ALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSM 240
Cdd:PRK11264 158 ALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEM 204
cbiO PRK13642
energy-coupling factor transporter ATPase;
42-256 1.95e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 65.88  E-value: 1.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLtkVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKE-LLRV 120
Cdd:PRK13642   2 NKILEVENL--VFKYEKESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAEnVWNL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQF-DALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYP 199
Cdd:PRK13642  80 RRKIGMVFQNpDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRP 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 200 SLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLT-SHSMEECeALCTRLGIMVNG 256
Cdd:PRK13642 160 EIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSiTHDLDEA-ASSDRILVMKAG 216
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
72-250 2.08e-12

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 64.87  E-value: 2.08e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK-ELLRVQQSIGYCPqfdALFEDLTAREHLELYTRLR 150
Cdd:PRK13543  34 VDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATRgDRSRFMAYLGHLP---GLKADLSTLENLHFLCGLH 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 151 GipwKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTG 230
Cdd:PRK13543 111 G---RRAKQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEGITLVNRMISAHLRGG 187

                        170       180
                 ....*....|....*....|
gi 641957197 231 RSVVLTSHSMEECEALCTRL 250
Cdd:PRK13543 188 GAALVTTHGAYAAPPVRTRM 207
ArpD COG4618
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ...
 70-262 3.40e-12

ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443660 [Multi-domain]  Cd Length: 563  Bit Score: 65.92  E-value: 3.40e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---LKELLRvqQSIGYCPQFDALFEDlTAREHLely 146
Cdd:COG4618  353 FSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLsqwDREELG--RHIGYLPQDVELFDG-TIAENI--- 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 147 TRLRGIpwkDEERVVSWAleklelsKYAD-------MPAGtY-----------SGGNKRKLSTAIALIGYPSLVFLDEPT 208
Cdd:COG4618  427 ARFGDA---DPEKVVAAA-------KLAGvhemilrLPDG-YdtrigeggarlSGGQRQRIGLARALYGDPRLVVLDEPN 495

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 209 TGMDPKARRFLWNLILDILKTGRSVVLTSHSMeecEAL--CTRLGIMVNGRFKCLG 262
Cdd:COG4618  496 SNLDDEGEAALAAAIRALKARGATVVVITHRP---SLLaaVDKLLVLRDGRVQAFG 548
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 42-238 4.25e-12

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 65.73  E-value: 4.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   42 NDMLKIDNLTKVYKSRkmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSsilkellrVQ 121
Cdd:TIGR03719 320 DKVIEAENLTKAFGDK-----LLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGET--------VK 386

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  122 qsIGYCPQFdalfedltaREHLElytrlrgiPWKDEERVVSWALEKLELSKYaDMPAGTY------------------SG 183
Cdd:TIGR03719 387 --LAYVDQS---------RDALD--------PNKTVWEEISGGLDIIKLGKR-EIPSRAYvgrfnfkgsdqqkkvgqlSG 446

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 641957197  184 GNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIlktGRSVVLTSH 238
Cdd:TIGR03719 447 GERNRVHLAKTLKSGGNVLLLDEPTNDLDVETLRALEEALLNF---AGCAVVISH 498
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
42-257 6.75e-12

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 64.27  E-value: 6.75e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRKMgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSsILKE--LLR 119
Cdd:PRK13635   3 EEIIRVEHISFRYPDAAT---YALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGM-VLSEetVWD 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQF-DALFEDLTAREHLELYTRLRGIPwKDE--ERVvSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALI 196
Cdd:PRK13635  79 VRRQVGMVFQNpDNQFVGATVQDDVAFGLENIGVP-REEmvERV-DQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 197 GYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLT-SHSMEECeALCTRLGIMVNGR 257
Cdd:PRK13635 157 LQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSiTHDLDEA-AQADRVIVMNKGE 217
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
32-257 7.02e-12

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 65.19  E-value: 7.02e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  32 RRRVLRGEADNDMLKIDNLTkvykSRKMGRilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGS 111
Cdd:PRK09700 253 MKENVSNLAHETVFEVRNVT----SRDRKK---VRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGK 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 112 SIL--KELLRVQQSIGYCPQF---DALFEDLTAREHLELYTRLRGIPWK---------DEERVVSWALEKLELSKYA-DM 176
Cdd:PRK09700 326 DISprSPLDAVKKGMAYITESrrdNGFFPNFSIAQNMAISRSLKDGGYKgamglfhevDEQRTAENQRELLALKCHSvNQ 405

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 177 PAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNG 256
Cdd:PRK09700 406 NITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEG 485


                 .
gi 641957197 257 R 257
Cdd:PRK09700 486 R 486
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
 70-238 8.66e-12

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 63.01  E-value: 8.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKELLRvqQSIGYCPQFDALFEDlTAREHLELy 146
Cdd:cd03254   24 FSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGidiRDISRKSLR--SMIGVVLQDTFLFSG-TIMENIRL- 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 147 trlrGIPWKDEERVVSWA--------LEKLE--LSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKAR 216
Cdd:cd03254  100 ----GRPNATDEEVIEAAkeagahdfIMKLPngYDTVLGENGGNLSQGERQLLAIARAMLRDPKILILDEATSNIDTETE 175

                        170       180
                 ....*....|....*....|..
gi 641957197 217 RFLWNLILDILKtGRSVVLTSH 238
Cdd:cd03254  176 KLIQEALEKLMK-GRTSIIIAH 196
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
 43-240 9.04e-12

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 63.59  E-value: 9.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  43 DMLKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGeafiggsSILKEllrVQQ 122
Cdd:PRK09544   3 SLVSLENVSVSFGQRRV-----LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEG-------VIKRN---GKL 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 SIGYCPQfdALFEDLTAREHLELYTRLR-GIPWKDeervVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSL 201
Cdd:PRK09544  68 RIGYVPQ--KLYLDTTLPLTVNRFLRLRpGTKKED----ILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQL 141

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 641957197 202 VFLDEPTTGMDPKARRFLWNLIlDILKT--GRSVVLTSHSM 240
Cdd:PRK09544 142 LVLDEPTQGVDVNGQVALYDLI-DQLRRelDCAVLMVSHDL 181
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
 78-263 9.82e-12

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 63.53  E-value: 9.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  78 FGLLGVNGAGKTTTFKMLT------GDESTTGGEAFIGGSSILK-ELLRVQQSIGYCPQFDALFEDLTAREHLELYTRLR 150
Cdd:PRK14246  39 FGIMGPSGSGKSTLLKVLNrlieiyDSKIKVDGKVLYFGKDIFQiDAIKLRKEVGMVFQQPNPFPHLSIYDNIAYPLKSH 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 151 GIPWKDE-ERVVSWALEKLELSKYA----DMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILD 225
Cdd:PRK14246 119 GIKEKREiKKIVEECLRKVGLWKEVydrlNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITE 198

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 641957197 226 iLKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:PRK14246 199 -LKNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGS 235
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
44-250 9.90e-12

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 63.57  E-value: 9.90e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL---KELLRV 120
Cdd:PRK11248   1 MLQISHLYADYGGKP-----ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEgpgAERGVV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQFDALfedltarEHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:PRK11248  76 FQNEGLLPWRNVQ-------DNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQ 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDIL-KTGRSVVLTSHSMEECEALCTRL 250
Cdd:PRK11248 149 LLLLDEPFGALDAFTREQMQTLLLKLWqETGKQVLLITHDIEEAVFMATEL 199
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
45-263 1.07e-11

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 63.47  E-value: 1.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYksrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLR-VQQS 123
Cdd:PRK10253   8 LRGEQLTLGY-----GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKeVARR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFEDLTARE--------HLELYTRLRgipwKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIAL 195
Cdd:PRK10253  83 IGLLAQNATTPGDITVQElvargrypHQPLFTRWR----KEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVL 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 196 IGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGS 263
Cdd:PRK10253 159 AQETAIMLLDEPTTWLDISHQIDLLELLSELNREkGYTLAAVLHDLNQACRYASHLIALREGKIVAQGA 227
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
 72-212 1.85e-11

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 61.89  E-value: 1.85e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTG---GEAFIGGSSILKELLRVQQSIGYCPQFDALFEDLTAREHLELYTR 148
Cdd:cd03233   30 VKPGEMVLVLGRPGSGCSTLLKALANRTEGNVsveGDIHYNGIPYKEFAEKYPGEIIYVSEEDVHFPTLTVRETLDFALR 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 149 LRGipwKDEERVVswaleklelskyadmpagtySGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:cd03233  110 CKG---NEFVRGI--------------------SGGERKRVSIAEALVSRASVLCWDNSTRGLD 150
cbiO PRK13640
energy-coupling factor transporter ATPase;
42-244 2.56e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 62.51  E-value: 2.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRKMGrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG----DESTTGGEAFIGGSSILKEL 117
Cdd:PRK13640   3 DNIVEFKHVSFTYPDSKKP---ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlllpDDNPNSKITVDGITLTAKTV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 118 LRVQQSIGYCPQF-DALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALI 196
Cdd:PRK13640  80 WDIREKVGIVFQNpDNQFVGATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILA 159

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 641957197 197 GYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECE 244
Cdd:PRK13640 160 VEPKIIILDESTSMLDPAGKEQILKLIRKLKKkNNLTVISITHDIDEAN 208
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
 65-257 3.18e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 63.10  E-value: 3.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  65 VDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLRvqQSIGYCPQ---FDALFEDL 137
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVtrspQDGLA--NGIVYISEdrkRDGLVLGM 345

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 138 TAREHLELyTRLR-------GIPWKDEERVVSWALEKLEL-SKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTT 209
Cdd:PRK10762 346 SVKENMSL-TALRyfsraggSLKHADEQQAVSDFIRLFNIkTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTR 424

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 641957197 210 GMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK10762 425 GVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGR 472
tagH PRK13545
teichoic acids export protein ATP-binding subunit; Provisional
 47-265 4.41e-11

teichoic acids export protein ATP-binding subunit; Provisional


Pssm-ID: 184130 [Multi-domain]  Cd Length: 549  Bit Score: 62.60  E-value: 4.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYKSRKMGRI-LAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILkellrVQQSIG 125
Cdd:PRK13545  21 FDKLKDLFFRSKDGEYhYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSAAL-----IAISSG 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 126 ycpqfdaLFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLD 205
Cdd:PRK13545  96 -------LNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVID 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 206 EPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQ 265
Cdd:PRK13545 169 EALSVGDQTFTKKCLDKMNEFKEQGKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDIK 228
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
 44-257 1.14e-10

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 60.14  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI--LKE--LLR 119
Cdd:COG4181    8 IIELRGLTKTVGTGA-GELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLfaLDEdaRAR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 V-QQSIGYCPQFDALFEDLTAREHLELYTRLRGIPwKDEERVVSWaLEKLELSKYADMPAGTYSGGNKRKLSTAIALIGY 198
Cdd:COG4181   87 LrARHVGFVFQSFQLLPTLTALENVMLPLELAGRR-DARARARAL-LERVGLGHRLDHYPAQLSGGEQQRVALARAFATE 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 199 PSLVFLDEPTTGMDPKARRflwnLILDIL-----KTGRSVVLTSHSmEECEALCTRLGIMVNGR 257
Cdd:COG4181  165 PAILFADEPTGNLDAATGE----QIIDLLfelnrERGTTLVLVTHD-PALAARCDRVLRLRAGR 223
PRK13546 PRK13546
teichoic acids export ABC transporter ATP-binding subunit TagH;
42-264 1.98e-10

teichoic acids export ABC transporter ATP-binding subunit TagH;


Pssm-ID: 184131 [Multi-domain]  Cd Length: 264  Bit Score: 59.83  E-value: 1.98e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYK---------------SRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEA 106
Cdd:PRK13546   2 NVSVNIKNVTKEYRiyrtnkermkdalipKHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 107 FIGGssilkELLRVQQSIGYCPQfdalfedLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNK 186
Cdd:PRK13546  82 DRNG-----EVSVIAISAGLSGQ-------LTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMR 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 187 RKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSI 264
Cdd:PRK13546 150 AKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGEL 227
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
 45-263 3.31e-10

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 60.20  E-value: 3.31e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   45 LKIDNLTKVYKSRKMGRILAVDrlclgVRPGECFGLLGVNGAGKTTTFKMLTGDES--TTGGEaFIGGSSILKELLRV-- 120
Cdd:TIGR03269   1 IEVKNLTKKFDGKEVLKNISFT-----IEEGEVLGILGRSGAGKSVLMHVLRGMDQyePTSGR-IIYHVALCEKCGYVer 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  121 QQSIGY-CP-------QFDALFEDLTAREHLELYTRL-----RGIPWKDEERVVSWALEKLELSKYA------------D 175
Cdd:TIGR03269  75 PSKVGEpCPvcggtlePEEVDFWNLSDKLRRRIRKRIaimlqRTFALYGDDTVLDNVLEALEEIGYEgkeavgravdliE 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  176 MP---------AGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEA 245
Cdd:TIGR03269 155 MVqlshrithiARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKaSGISMVLTSHWPEVIED 234

                         250
                  ....*....|....*...
gi 641957197  246 LCTRLGIMVNGRFKCLGS 263
Cdd:TIGR03269 235 LSDKAIWLENGEIKEEGT 252
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
 44-259 3.56e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 59.94  E-value: 3.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLT---KVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGdeSTTG---GEAFIGGS--SILK 115
Cdd:PRK13549 259 ILEVRNLTawdPVNPHIKR-----VDDVSFSLRRGEILGIAGLVGAGRTELVQCLFG--AYPGrweGEIFIDGKpvKIRN 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLRVQQSIGYCPQ---FDALFEDLTAREHLEL-----YTRLRGIPWKDEERVVSWALEKLEL-SKYADMPAGTYSGGNK 186
Cdd:PRK13549 332 PQQAIAQGIAMVPEdrkRDGIVPVMGVGKNITLaaldrFTGGSRIDDAAELKTILESIQRLKVkTASPELAIARLSGGNQ 411

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 187 RKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRFK 259
Cdd:PRK13549 412 QKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKLK 484
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
44-257 3.96e-10

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 58.93  E-value: 3.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKS----RKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKelLR 119
Cdd:PRK10419   3 LLNVSGLSHHYAHgglsGKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAK--LN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFED-LTA-----------REHLELYTRLrgipwkDEERVVSWALEKLEL----SKYADMPAGTYSG 183
Cdd:PRK10419  81 RAQRKAFRRDIQMVFQDsISAvnprktvreiiREPLRHLLSL------DKAERLARASEMLRAvdldDSVLDKRPPQLSG 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 184 GNKRKLSTAIALIGYPSLVFLDEPTTGMDpkarRFLWNLILDILK-----TGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK10419 155 GQLQRVCLARALAVEPKLLILDEAVSNLD----LVLQAGVIRLLKklqqqFGTACLFITHDLRLVERFCQRVMVMDNGQ 229
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
66-272 4.00e-10

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 59.01  E-value: 4.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  66 DRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK----ELLRVQQSIGYCPQFDALFEDLTA-- 139
Cdd:PRK11831  24 DNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAmsrsRLYTVRKRMSMLFQSGALFTDMNVfd 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 140 ------REHlelyTRLrgiPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRK--LSTAIALigYPSLVFLDEPTTGM 211
Cdd:PRK11831 104 nvayplREH----TQL---PAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRaaLARAIAL--EPDLIMFDEPFVGQ 174

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 212 DPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHLKNRSE 272
Cdd:PRK11831 175 DPITMGVLVKLISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPD 236
MsbA_lipidA TIGR02203
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ...
 19-238 5.19e-10

lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 131258 [Multi-domain]  Cd Length: 571  Bit Score: 59.34  E-value: 5.19e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   19 QPIEDDDEDVASERrrvLRGEadndmLKIDNLTKVYKSRKmgrILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGD 98
Cdd:TIGR02203 313 SPPEKDTGTRAIER---ARGD-----VEFRNVTFRYPGRD---RPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRF 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   99 ESTTGGEAFIGGSSILKELLR-VQQSIGYCPQFDALFEDLTAREhlELYTRLRGIpwkDEERVVSwALEKLELSKYAD-M 176
Cdd:TIGR02203 382 YEPDSGQILLDGHDLADYTLAsLRRQVALVSQDVVLFNDTIANN--IAYGRTEQA---DRAEIER-ALAAAYAQDFVDkL 455

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197  177 PAGTY----------SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRfLWNLILDILKTGRSVVLTSH 238
Cdd:TIGR02203 456 PLGLDtpigengvllSGGQRQRLAIARALLKDAPILILDEATSALDNESER-LVQAALERLMQGRTTLVIAH 526
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
64-238 8.52e-10

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 59.02  E-value: 8.52e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----LKELLRvqqSIGYCPQfDA-LFEDlT 138
Cdd:COG1132  355 VLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIrdltLESLRR---QIGVVPQ-DTfLFSG-T 429

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 139 AREHLelytRLrGIPWKDEERVVsWALEKLELSKY-ADMPAG----------TYSGGNKRKLSTAIALIGYPSLVFLDEP 207
Cdd:COG1132  430 IRENI----RY-GRPDATDEEVE-EAAKAAQAHEFiEALPDGydtvvgergvNLSGGQRQRIAIARALLKDPPILILDEA 503

                        170       180       190
                 ....*....|....*....|....*....|.
gi 641957197 208 TTGMDPKARRFLWNLILDILKtGRSVVLTSH 238
Cdd:COG1132  504 TSALDTETEALIQEALERLMK-GRTTIVIAH 533
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 7-247 1.33e-09

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 58.18  E-value: 1.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   7 CVFYNRRVPVSSQPIEdddedvaSERRRVLRGEADND----------MLKIDNLTKVYKSRK--MGRIL----AVDRLCL 70
Cdd:PRK15134 235 CVEQNRAATLFSAPTH-------PYTQKLLNSEPSGDpvplpepaspLLDVEQLQVAFPIRKgiLKRTVdhnvVVKNISF 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  71 GVRPGECFGLLGVNGAGKTTT-FKMLTGDESTtgGEAFIGGSSIlkELLRVQQSIGYCPQFDALFED----LTAR----- 140
Cdd:PRK15134 308 TLRPGETLGLVGESGSGKSTTgLALLRLINSQ--GEIWFDGQPL--HNLNRRQLLPVRHRIQVVFQDpnssLNPRlnvlq 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 141 ---EHLELYTRLRGiPWKDEERVVSwALEKLELS-----KYadmPAgTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:PRK15134 384 iieEGLRVHQPTLS-AAQREQQVIA-VMEEVGLDpetrhRY---PA-EFSGGQRQRIAIARALILKPSLIILDEPTSSLD 457

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 641957197 213 pkarRFLWNLILDILKT-----GRSVVLTSHSMEECEALC 247
Cdd:PRK15134 458 ----KTVQAQILALLKSlqqkhQLAYLFISHDLHVVRALC 493
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
 72-267 2.15e-09

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 56.95  E-value: 2.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL-----KELLRVQQSIGYCPQF--DALFEDlTAREHLE 144
Cdd:PRK13634  30 IPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITagkknKKLKPLRKKVGIVFQFpeHQLFEE-TVEKDIC 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 145 LYTRLRGIPWKDEERVVSWALEKLELS-KYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLI 223
Cdd:PRK13634 109 FGPMNFGVSEEDAKQKAREMIELVGLPeELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMF 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 641957197 224 LDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSIQHL 267
Cdd:PRK13634 189 YKLHKEkGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQGTPREI 233
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
44-271 2.31e-09

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 56.13  E-value: 2.31e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMgrilavdRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGS------------ 111
Cdd:PRK10771   1 MLKLTDITWLYHHLPM-------RFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQdhtttppsrrpv 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 112 SILKellrvqqsigycpQFDALFEDLTAREH--LELYTRLRGIPwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKL 189
Cdd:PRK10771  74 SMLF-------------QENNLFSHLTVAQNigLGLNPGLKLNA--AQREKLHAIARQMGIEDLLARLPGQLSGGQRQRV 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVL-TSHSMEECEALCTRLGIMVNGRFKCLGSIQHLK 268
Cdd:PRK10771 139 ALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQERQLTLLmVSHSLEDAARIAPRSLVVADGRIAWDGPTDELL 218


                 ...
gi 641957197 269 NRS 271
Cdd:PRK10771 219 SGK 221
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 179-257 2.37e-09

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 57.43  E-value: 2.37e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 179 GTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK10982 390 GSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGL 468
PRK10522 PRK10522
multidrug transporter membrane component/ATP-binding component; Provisional
 64-238 3.10e-09

multidrug transporter membrane component/ATP-binding component; Provisional


Pssm-ID: 236707 [Multi-domain]  Cd Length: 547  Bit Score: 57.29  E-value: 3.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRvqqsiGYCPQFDALFEDLtareHl 143
Cdd:PRK10522 338 SVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPE-----DYRKLFSAVFTDF----H- 407

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 144 eLYTRL---RGIPwKDEERVVSWaLEKLELSKYADMPAGT-----YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKA 215
Cdd:PRK10522 408 -LFDQLlgpEGKP-ANPALVEKW-LERLKMAHKLELEDGRisnlkLSKGQKKRLALLLALAEERDILLLDEWAADQDPHF 484

                        170       180
                 ....*....|....*....|....
gi 641957197 216 RRFLWNLILDILK-TGRSVVLTSH 238
Cdd:PRK10522 485 RREFYQVLLPLLQeMGKTIFAISH 508
PRK10636 PRK10636
putative ABC transporter ATP-binding protein; Provisional
 42-225 3.35e-09

putative ABC transporter ATP-binding protein; Provisional


Pssm-ID: 236729 [Multi-domain]  Cd Length: 638  Bit Score: 57.10  E-value: 3.35e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  42 NDMLKIDNLTKVYKSRkmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEafIGGSSILKellrvq 121
Cdd:PRK10636 310 NPLLKMEKVSAGYGDR-----IILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGE--IGLAKGIK------ 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 qsIGYCP--QFDALFEDLTAREHL------ELYTRLR----GIPWKDEervvswaleklelsKYADmPAGTYSGGNKRKL 189
Cdd:PRK10636 377 --LGYFAqhQLEFLRADESPLQHLarlapqELEQKLRdylgGFGFQGD--------------KVTE-ETRRFSGGEKARL 439

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILD 225
Cdd:PRK10636 440 VLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALID 475
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
 47-212 6.00e-09

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 56.10  E-value: 6.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   47 IDNLTKVYKSRKmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAfiggssilkellRVQQSI-- 124
Cdd:TIGR03719   7 MNRVSKVVPPKK--EIL--KDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEA------------RPQPGIkv 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  125 GYCPQFDALFEDLTAREHLE--------LYTRLRGI------PWKD-----------EERVVS---WALE-KLELSKYA- 174
Cdd:TIGR03719  71 GYLPQEPQLDPTKTVRENVEegvaeikdALDRFNEIsakyaePDADfdklaaeqaelQEIIDAadaWDLDsQLEIAMDAl 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 641957197  175 -----DMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:TIGR03719 151 rcppwDADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
 70-238 8.17e-09

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 56.11  E-value: 8.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKellRVQQSigycPQ-------FDALFEDLTAR-E 141
Cdd:PRK11147  24 LHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVA---RLQQD----PPrnvegtvYDFVAEGIEEQaE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLELY-------------------TRLRGI-----PWKDEERVVSwALEKLELSkyADMPAGTYSGGNKRKLSTAIALIG 197
Cdd:PRK11147  97 YLKRYhdishlvetdpseknlnelAKLQEQldhhnLWQLENRINE-VLAQLGLD--PDAALSSLSGGWLRKAALGRALVS 173

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 641957197 198 YPSLVFLDEPTTGMDPKARRFLWNLILDIlktGRSVVLTSH 238
Cdd:PRK11147 174 NPDVLLLDEPTNHLDIETIEWLEGFLKTF---QGSIIFISH 211
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 48-238 8.24e-09

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 55.90  E-value: 8.24e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  48 DNLTKVYKSRkmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSsilkellrVQqsIGYC 127
Cdd:PRK11819 328 ENLSKSFGDR-----LLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGET--------VK--LAYV 392

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 128 PQFdalfedltaREHLElytrlrgiPWKDEERVVSWALEKLELSKYaDMP------------------AGTYSGGNKRKL 189
Cdd:PRK11819 393 DQS---------RDALD--------PNKTVWEEISGGLDIIKVGNR-EIPsrayvgrfnfkggdqqkkVGVLSGGERNRL 454

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDIlktGRSVVLTSH 238
Cdd:PRK11819 455 HLAKTLKQGGNVLLLDEPTNDLDVETLRALEEALLEF---PGCAVVISH 500
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
72-212 8.86e-09

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 55.59  E-value: 8.86e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEafiggssILKELlrvqqSIGYCPQFDALFEDLTAREHLE-LYTRLR 150
Cdd:PRK13409 362 IYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGE-------VDPEL-----KISYKPQYIKPDYDGTVEDLLRsITDDLG 429

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 641957197 151 GIPWKDEervvswALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:PRK13409 430 SSYYKSE------IIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 29-257 9.17e-09

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 55.85  E-value: 9.17e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  29 ASERRRVLRGEADND--MLKIDNLTKVYKSRK------MGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDES 100
Cdd:COG4172  258 AAEPRGDPRPVPPDAppLLEARDLKVWFPIKRglfrrtVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLIP 337

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 101 tTGGEAFIGGSSIL----KELLRVQQSIgycpQfdALFED--------LTAREHLELYTRLRGIPWKDEERV--VSWALE 166
Cdd:COG4172  338 -SEGEIRFDGQDLDglsrRALRPLRRRM----Q--VVFQDpfgslsprMTVGQIIAEGLRVHGPGLSAAERRarVAEALE 410

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 167 KLELSkyADMpAGTY----SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDpkarRFLWNLILDILKT-----GRSVVLTS 237
Cdd:COG4172  411 EVGLD--PAA-RHRYphefSGGQRQRIAIARALILEPKLLVLDEPTSALD----VSVQAQILDLLRDlqrehGLAYLFIS 483

                        250       260
                 ....*....|....*....|
gi 641957197 238 HSMEECEALCTRLGIMVNGR 257
Cdd:COG4172  484 HDLAVVRALAHRVMVMKDGK 503
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 72-212 9.61e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 55.56  E-value: 9.61e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEafiggssilkelLRVQQSIGYCPQFDALFEDLTAREHLE--LYTRL 149
Cdd:COG1245  363 IREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGE------------VDEDLKISYKPQYISPDYDGTVEEFLRsaNTDDF 430

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 150 RGIPWKDEervvswALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:COG1245  431 GSSYYKTE------IIKPLGLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
 45-263 1.46e-08

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 53.30  E-value: 1.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTkVYKSRKmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDEST--TGGEAFIGGSSILkELL---R 119
Cdd:cd03217    1 LEIKDLH-VSVGGK--EIL--KGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYevTEGEILFKGEDIT-DLPpeeR 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHlelytrLRGIpwkDEervvswaleklelskyadmpagTYSGGNKRKLSTAIALIGYP 199
Cdd:cd03217   75 ARLGIFLAFQYPPEIPGVKNADF------LRYV---NE----------------------GFSGGEKKRNEILQLLLLEP 123

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 200 SLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEAL-CTRLGIMVNGRFKCLGS 263
Cdd:cd03217  124 DLAILDEPDSGLDIDALRLVAEVINKLREEGKSVLIITHYQRLLDYIkPDRVHVLYDGRIVKSGD 188
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
 70-238 1.88e-08

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 53.77  E-value: 1.88e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlKEL----LRvqQSIGYCPQFDALFEDlTAREHLEl 145
Cdd:cd03253   22 FTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI-REVtldsLR--RAIGVVPQDTVLFND-TIGYNIR- 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 146 YTRLRGipwkDEERVVswaleklELSKYAD-------MPAGtY-----------SGGNKRKLSTAIALIGYPSLVFLDEP 207
Cdd:cd03253   97 YGRPDA----TDEEVI-------EAAKAAQihdkimrFPDG-YdtivgerglklSGGEKQRVAIARAILKNPPILLLDEA 164

                        170       180       190
                 ....*....|....*....|....*....|.
gi 641957197 208 TTGMDPKARRFLWNLILDILKtGRSVVLTSH 238
Cdd:cd03253  165 TSALDTHTEREIQAALRDVSK-GRTTIVIAH 194
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
 44-256 2.05e-08

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 53.63  E-value: 2.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrilAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLT--GD---ESTTGGEAFIGGSSILK--- 115
Cdd:PRK14239   5 ILQVSDLSVYYNKKK-----ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDlnpEVTITGSIVYNGHNIYSprt 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLRVQQSIGYCPQFDALFEdLTAREHLELYTRLRGIpwKDEErVVSWALEKL--------ELSKYADMPAGTYSGGNKR 187
Cdd:PRK14239  80 DTVDLRKEIGMVFQQPNPFP-MSIYENVVYGLRLKGI--KDKQ-VLDEAVEKSlkgasiwdEVKDRLHDSALGLSGGQQQ 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197 188 KLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDiLKTGRSVVLTSHSMEECEALCTRLGIMVNG 256
Cdd:PRK14239 156 RVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLG-LKDDYTMLLVTRSMQQASRISDRTGFFLDG 223
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
 28-267 2.07e-08

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 53.95  E-value: 2.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  28 VASERRRVLRGEADNDM----LKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG-DESTT 102
Cdd:PRK14271   1 MACERLGGQSGAADVDAaapaMAAVNLTLGFAGKTV-----LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRmNDKVS 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 103 G----GEAFIGGSSIL--KELLRVQQSIGYC-----PQFDALFEDLTA--REH-LELYTRLRGIPWKDEERVVSWALEKL 168
Cdd:PRK14271  76 GyrysGDVLLGGRSIFnyRDVLEFRRRVGMLfqrpnPFPMSIMDNVLAgvRAHkLVPRKEFRGVAQARLTEVGLWDAVKD 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 169 ELSkyaDMPAgTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDiLKTGRSVVLTSHSMEECEALCT 248
Cdd:PRK14271 156 RLS---DSPF-RLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRS-LADRLTVIIVTHNLAQAARISD 230

                        250
                 ....*....|....*....
gi 641957197 249 RLGIMVNGRFKCLGSIQHL 267
Cdd:PRK14271 231 RAALFFDGRLVEEGPTEQL 249
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
44-216 2.44e-08

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 54.08  E-value: 2.44e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKsrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSsilkellRVQQ- 122
Cdd:PRK11650   3 GLKLQAVRKSYD----GKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGR-------VVNEl 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 -----SIGYCPQFDALFEDLTAREHLELYTRLRGIPwKDE-ERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALI 196
Cdd:PRK11650  72 epadrDIAMVFQNYALYPHMSVRENMAYGLKIRGMP-KAEiEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIV 150

                        170       180
                 ....*....|....*....|.
gi 641957197 197 GYPSlVFL-DEPTTGMDPKAR 216
Cdd:PRK11650 151 REPA-VFLfDEPLSNLDAKLR 170
bacteriocin_ABC TIGR01193
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ...
 64-212 3.05e-08

ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]


Pssm-ID: 130261 [Multi-domain]  Cd Length: 708  Bit Score: 54.36  E-value: 3.05e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKELLRvqQSIGYCPQFDALFeDLTAR 140
Cdd:TIGR01193 489 ILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGfslKDIDRHTLR--QFINYLPQEPYIF-SGSIL 565

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 641957197  141 EHLELYTRlRGIPWKDEERVVSWA-----LEKLELSKYADMP--AGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:TIGR01193 566 ENLLLGAK-ENVSQDEIWAACEIAeikddIENMPLGYQTELSeeGSSISGGQKQRIALARALLTDSKVLILDESTSNLD 643
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
70-216 3.13e-08

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 53.88  E-value: 3.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSiLKELLRVQQSIGYCPQFDALFEDLTAREHLELYTRL 149
Cdd:PRK11000  24 LDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKR-MNDVPPAERGVGMVFQSYALYPHLSVAENMSFGLKL 102

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 150 RGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKAR 216
Cdd:PRK11000 103 AGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDAALR 169
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 72-216 3.40e-08

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 53.18  E-value: 3.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEafiggssILKELlrvqQSIGYCPQFDALFEDLTAREHLELYTRLRG 151
Cdd:cd03237   22 ISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGD-------IEIEL----DTVSYKPQYIKADYEGTVRDLLSSITKDFY 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 641957197 152 IP--WKDEervvswALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKAR 216
Cdd:cd03237   91 THpyFKTE------IAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQR 151
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
 35-257 3.53e-08

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 53.57  E-value: 3.53e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  35 VLRGEADNDMLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG---DESTTGGEAFIGGS 111
Cdd:PRK09473   3 PLAQQQADALLDVKDLRVTFSTPD-GDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGllaANGRIGGSATFNGR 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 112 SIL----KELLRVQQSigycpQFDALFED-LTArehLELYTRL-----------RGIPWKD--EERVVSW-ALEKLELSK 172
Cdd:PRK09473  82 EILnlpeKELNKLRAE-----QISMIFQDpMTS---LNPYMRVgeqlmevlmlhKGMSKAEafEESVRMLdAVKMPEARK 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 173 YADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLiLDILKT--GRSVVLTSHSMEECEALCTRL 250
Cdd:PRK09473 154 RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTL-LNELKRefNTAIIMITHDLGVVAGICDKV 232


                 ....*..
gi 641957197 251 GIMVNGR 257
Cdd:PRK09473 233 LVMYAGR 239
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
 72-238 4.64e-08

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 52.75  E-value: 4.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTG------------DESTTGGEAFIGG------SSILKELLRVQQSIGYCPQFDAL 133
Cdd:cd03236   23 PREGQVLGLVGPNGIGKSTALKILAGklkpnlgkfddpPDWDEILDEFRGSelqnyfTKLLEGDVKVIVKPQYVDLIPKA 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 FEDLTarehLELYTRlrgipwKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDP 213
Cdd:cd03236  103 VKGKV----GELLKK------KDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172

                        170       180
                 ....*....|....*....|....*
gi 641957197 214 KARRFLWNLILDILKTGRSVVLTSH 238
Cdd:cd03236  173 KQRLNAARLIRELAEDDNYVLVVEH 197
AAA_21 pfam13304
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ...
 124-241 4.91e-08

AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.


Pssm-ID: 433102 [Multi-domain]  Cd Length: 303  Bit Score: 53.16  E-value: 4.91e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  124 IGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSwaLEKLELSKYADMPAGTYSGGNKRKLSTAIALI---GYPS 200
Cdd:pfam13304 182 KELLQRLVRGLKLADLNLSDLGEGIEKSLLVDDRLRERG--LILLENGGGGELPAFELSDGTKRLLALLAALLsalPKGG 259

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 641957197  201 LVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:pfam13304 260 LLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTHSPL 300
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
 45-269 5.06e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 53.76  E-value: 5.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    45 LKIDNLTKVYKSRkmGRILAVDrLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRVQQSI 124
Cdd:TIGR01271 1218 MDVQGLTAKYTEA--GRAVLQD-LSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTEGEIQIDGVSWNSVTLQTWRKAF 1294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   125 GYCPQFDALFEDlTAREHLELYTRlrgipWKDEE--RVVSWALEKLELSKYAD-----MPAGTY--SGGNKRKLSTAIAL 195
Cdd:TIGR01271 1295 GVIPQKVFIFSG-TFRKNLDPYEQ-----WSDEEiwKVAEEVGLKSVIEQFPDkldfvLVDGGYvlSNGHKQLMCLARSI 1368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   196 IGYPSLVFLDEPTTGMDPkarrFLWNLILDILKTGRS---VVLTSHSME---ECEALctrlgIMVNG-RFKCLGSIQHLK 268
Cdd:TIGR01271 1369 LSKAKILLLDEPSAHLDP----VTLQIIRKTLKQSFSnctVILSEHRVEallECQQF-----LVIEGsSVKQYDSIQKLL 1439


                   .
gi 641957197   269 N 269
Cdd:TIGR01271 1440 N 1440
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
 65-217 5.27e-08

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 52.41  E-value: 5.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  65 VDRLCLGVRPGEcFGLL-GVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK---ELLRVQQSigYCPQFDALFEDlTAR 140
Cdd:PRK10247  23 LNNISFSLRAGE-FKLItGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTlkpEIYRQQVS--YCAQTPTLFGD-TVY 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 141 EHLELYTRLRGIpwKDEERVVSWALEKLELSKYA-DMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARR 217
Cdd:PRK10247  99 DNLIFPWQIRNQ--QPDPAIFLDDLERFALPDTIlTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKH 174
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
 45-249 5.34e-08

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 53.36  E-value: 5.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEafiggssilkellrVQQS- 123
Cdd:PRK15064 320 LEVENLTKGFDNGPL-----FKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGT--------------VKWSe 380

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 ---IGYCPQ-----FDalfEDLTAREHLELYTRLrgipwKDEERVVSWALEKLELSK-YADMPAGTYSGGNKRKLSTAIA 194
Cdd:PRK15064 381 nanIGYYAQdhaydFE---NDLTLFDWMSQWRQE-----GDDEQAVRGTLGRLLFSQdDIKKSVKVLSGGEKGRMLFGKL 452

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 195 LIGYPSLVFLDEPTTGMDPKARRFLwNLILDILKTgrSVVLTSHSMEECEALCTR 249
Cdd:PRK15064 453 MMQKPNVLVMDEPTNHMDMESIESL-NMALEKYEG--TLIFVSHDREFVSSLATR 504
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
 45-244 5.43e-08

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 52.09  E-value: 5.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLRV 120
Cdd:cd03248   12 VKFQNVTFAYPTRPDTLVL--QDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISqyehKYLHSK 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 121 QQSIGYCPQfdaLFEDlTAREHLELytrlrGIPWKDEERVVSWA--------LEKLELSKYADM--PAGTYSGGNKRKLS 190
Cdd:cd03248   90 VSLVGQEPV---LFAR-SLQDNIAY-----GLQSCSFECVKEAAqkahahsfISELASGYDTEVgeKGSQLSGGQKQRVA 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 191 TAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILkTGRSVVLTSHSMEECE 244
Cdd:cd03248  161 IARALIRNPQVLILDEATSALDAESEQQVQQALYDWP-ERRTVLVIAHRLSTVE 213
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
 54-238 5.55e-08

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 52.16  E-value: 5.55e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  54 YKSRKMGRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIlKEL----LRVQqsIGYCPQ 129
Cdd:cd03249   10 YPSRPDVPIL--KGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDI-RDLnlrwLRSQ--IGLVSQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 130 FDALFeDLTAREHLELytrlrGIPWKDEERVVSwALEKLELSKY-ADMPAG----------TYSGGNKRKLSTAIALIGY 198
Cdd:cd03249   85 EPVLF-DGTIAENIRY-----GKPDATDEEVEE-AAKKANIHDFiMSLPDGydtlvgergsQLSGGQKQRIAIARALLRN 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 641957197 199 PSLVFLDEPTTGMDPKARRflwnLI---LDILKTGRSVVLTSH 238
Cdd:cd03249  158 PKILLLDEATSALDAESEK----LVqeaLDRAMKGRTTIVIAH 196
PRK13541 PRK13541
cytochrome c biogenesis protein CcmA; Provisional
 68-239 7.29e-08

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184128 [Multi-domain]  Cd Length: 195  Bit Score: 51.41  E-value: 7.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  68 LCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKellrVQQS-IGYCPQFDALFEDLTAREHLELY 146
Cdd:PRK13541  19 LSITFLPSAITYIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINN----IAKPyCTYIGHNLGLKLEMTVFENLKFW 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 147 TRLRgipwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI 226
Cdd:PRK13541  95 SEIY-----NSAETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENRDLLNNLIVMK 169

                        170
                 ....*....|...
gi 641957197 227 LKTGRSVVLTSHS 239
Cdd:PRK13541 170 ANSGGIVLLSSHL 182
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
 44-238 1.01e-07

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 52.38  E-value: 1.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTF----KMLTGDESTTGGEAFIGGSSIL----K 115
Cdd:COG4172    6 LLSVEDLSVAFGQGG-GTVEAVKGVSFDIAAGETLALVGESGSGKSVTAlsilRLLPDPAAHPSGSILFDGQDLLglseR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 ELLRVQ-QSIGYCPQfdalfEDLTA-----------REHLELYTRLRGIPWkdEERVVSWaLEKLELSKyADMPAGTY-- 181
Cdd:COG4172   85 ELRRIRgNRIAMIFQ-----EPMTSlnplhtigkqiAEVLRLHRGLSGAAA--RARALEL-LERVGIPD-PERRLDAYph 155

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 641957197 182 --SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDP--KARrflwnlILDILK-----TGRSVVLTSH 238
Cdd:COG4172  156 qlSGGQRQRVMIAMALANEPDLLIADEPTTALDVtvQAQ------ILDLLKdlqreLGMALLLITH 215
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
 45-241 1.36e-07

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 51.63  E-value: 1.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG------------------DESTTGGEA 106
Cdd:PRK13651   3 IKVKNIVKIFNKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNAlllpdtgtiewifkdeknKKKTKEKEK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 107 FIGGSSILKELLR-------VQQSIGYCPQFD--ALFEDlTAREHLELYTRLRGIPwKDE--ERvvswALEKLEL----S 171
Cdd:PRK13651  83 VLEKLVIQKTRFKkikkikeIRRRVGVVFQFAeyQLFEQ-TIEKDIIFGPVSMGVS-KEEakKR----AAKYIELvgldE 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 172 KYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:PRK13651 157 SYLQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLD 226
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
44-226 1.69e-07

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 50.94  E-value: 1.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSR----KMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFI-------GGSS 112
Cdd:PRK15112   4 LLEVRNLSKTFRYRtgwfRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIddhplhfGDYS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 113 ILKELLRVqqsigycpqfdaLFED----LTAREH--------LELYTRLRGipwKDEERVVSWALEKLEL-----SKYAD 175
Cdd:PRK15112  84 YRSQRIRM------------IFQDpstsLNPRQRisqildfpLRLNTDLEP---EQREKQIIETLRQVGLlpdhaSYYPH 148

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 641957197 176 MPAgtysGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI 226
Cdd:PRK15112 149 MLA----PGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLEL 195
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
 45-213 2.12e-07

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 50.18  E-value: 2.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSrkmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTT----FKMLtgdeSTTGGEAFIGG---SSILKEL 117
Cdd:cd03244    3 IEFKNVSLRYRP---NLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLllalFRLV----ELSSGSILIDGvdiSKIGLHD 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 118 LRvqQSIGYCPQFDALFEDlTAREHLELYTRlrgipWKDEERvvsW-ALEKLELSKY-ADMPAG----------TYSGGN 185
Cdd:cd03244   76 LR--SRISIIPQDPVLFSG-TIRSNLDPFGE-----YSDEEL---WqALERVGLKEFvESLPGGldtvveeggeNLSVGQ 144

                        170       180
                 ....*....|....*....|....*...
gi 641957197 186 KRKLSTAIALIGYPSLVFLDEPTTGMDP 213
Cdd:cd03244  145 RQLLCLARALLRKSKILVLDEATASVDP 172
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 73-238 2.67e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 51.32  E-value: 2.67e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  73 RPGECFGLLGVNGAGKTTTFKMLTGD--------ESTTGGEAFI---GGSSI---LKEL----LRVQQSIGYCPQFDALF 134
Cdd:COG1245   97 KKGKVTGILGPNGIGKSTALKILSGElkpnlgdyDEEPSWDEVLkrfRGTELqdyFKKLangeIKVAHKPQYVDLIPKVF 176

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 135 eDLTAREHLELYtrlrgipwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPK 214
Cdd:COG1245  177 -KGTVRELLEKV---------DERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIY 246

                        170       180
                 ....*....|....*....|....
gi 641957197 215 ARRFLWNLILDILKTGRSVVLTSH 238
Cdd:COG1245  247 QRLNVARLIRELAEEGKYVLVVEH 270
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
60-212 2.87e-07

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 50.56  E-value: 2.87e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  60 GRILaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSIL----KELLRvqqSIGYCPQFDALFE 135
Cdd:PRK10575  23 GRTL-LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLEswssKAFAR---KVAYLPQQLPAAE 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 136 DLTAREhlelytrLRGI---PW---------KDEERVVSwALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:PRK10575  99 GMTVRE-------LVAIgryPWhgalgrfgaADREKVEE-AISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLL 170


                 ....*....
gi 641957197 204 LDEPTTGMD 212
Cdd:PRK10575 171 LDEPTSALD 179
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
70-241 4.07e-07

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 49.97  E-value: 4.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  70 LGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI---------LK-------ELLRVQQSIGYcpQFDAL 133
Cdd:PRK10619  26 LQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTInlvrdkdgqLKvadknqlRLLRTRLTMVF--QHFNL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 FEDLTAREH-LELYTRLRGIPWKD-EERVVSWaLEKLELSKYADmpaGTY----SGGNKRKLSTAIALIGYPSLVFLDEP 207
Cdd:PRK10619 104 WSHMTVLENvMEAPIQVLGLSKQEaRERAVKY-LAKVGIDERAQ---GKYpvhlSGGQQQRVSIARALAMEPEVLLFDEP 179

                        170       180       190
                 ....*....|....*....|....*....|....
gi 641957197 208 TTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:PRK10619 180 TSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMG 213
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
 45-238 4.17e-07

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 50.35  E-value: 4.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRK-----MGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK---- 115
Cdd:PRK11308   6 LQAIDLKKHYPVKRglfkpERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKadpe 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 --ELLRvqQSIgycpQ--FDALFEDLTAR--------EHLELYTRLRGipwkdEERV--VSWALEKLEL-----SKYADM 176
Cdd:PRK11308  86 aqKLLR--QKI----QivFQNPYGSLNPRkkvgqileEPLLINTSLSA-----AERRekALAMMAKVGLrpehyDRYPHM 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 641957197 177 pagtYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSH 238
Cdd:PRK11308 155 ----FSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQElGLSYVFISH 213
hmuV PRK13547
heme ABC transporter ATP-binding protein;
44-212 4.56e-07

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 49.83  E-value: 4.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKvykSRKMGRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGD---ESTTGGEAFIGGSSILKELL-- 118
Cdd:PRK13547   1 MLTADHLHV---ARRHRAIL--RDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDltgGGAPRGARVTGDVTLNGEPLaa 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 119 ----RVQQSIGYCPQFDALFEDLTAREHLEL----YTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLS 190
Cdd:PRK13547  76 idapRLARLRAVLPQAAQPAFAFSAREIVLLgrypHARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQ 155

                        170       180       190
                 ....*....|....*....|....*....|.
gi 641957197 191 TAIAL---------IGYPSLVFLDEPTTGMD 212
Cdd:PRK13547 156 FARVLaqlwpphdaAQPPRYLLLDEPTAALD 186
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 72-212 5.14e-07

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 50.49  E-value: 5.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197    72 VRPGECFGLLGVNGAGKTTTFKMLTG--DESTTGGEAFIGGSSILKELLRVQ--QSIGYCPQFDALFEDLTAREHLELYT 147
Cdd:TIGR00956   84 IKPGELTVVLGRPGSGCSTLLKTIASntDGFHIGVEGVITYDGITPEEIKKHyrGDVVYNAETDVHFPHLTVGETLDFAA 163

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197   148 RLRGIPWKDE--------ERVVSWALEKLELSKYADMPAGT-----YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:TIGR00956  164 RCKTPQNRPDgvsreeyaKHIADVYMATYGLSHTRNTKVGNdfvrgVSGGERKRVSIAEASLGGAKIQCWDNATRGLD 241
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
44-238 5.43e-07

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 50.49  E-value: 5.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI-------LKE 116
Cdd:PRK10535   4 LLELKDIRRSYPSGE-EQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVatldadaLAQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 117 LLRvqQSIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALI 196
Cdd:PRK10535  83 LRR--EHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALM 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 641957197 197 GYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:PRK10535 161 NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTH 202
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 61-223 6.38e-07

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 50.01  E-value: 6.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  61 RILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGD-------ESTTGGEAFIGGSSILKellrVQQSIGYcpqfdal 133
Cdd:PRK10938 274 PIL--HNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDhpqgysnDLTLFGRRRGSGETIWD----IKKHIGY------- 340

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 fedLTAREHLE--LYTRLR-----------GI--PWKDEERVVS--WaLEKLELSKY-ADMPAGTYSGGNKRKLSTAIAL 195
Cdd:PRK10938 341 ---VSSSLHLDyrVSTSVRnvilsgffdsiGIyqAVSDRQQKLAqqW-LDILGIDKRtADAPFHSLSWGQQRLALIVRAL 416

                        170       180       190
                 ....*....|....*....|....*....|..
gi 641957197 196 IGYPSLVFLDEPTTGMDPKAR----RFLWNLI 223
Cdd:PRK10938 417 VKHPTLLILDEPLQGLDPLNRqlvrRFVDVLI 448
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
 38-238 7.83e-07

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 49.81  E-value: 7.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  38 GEADNDMLKIDNLTkVYKSRkmGRILaVDRLCLGVRPGEcfGLL--GVNGAGKTTTFKMLTG-DESTTGgeafiggssil 114
Cdd:COG4178  356 ETSEDGALALEDLT-LRTPD--GRPL-LEDLSLSLKPGE--RLLitGPSGSGKSTLLRAIAGlWPYGSG----------- 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 115 kellrvqqSIGYCPQFDALFedLTAREHLELYTrLRGI--------PWKDEErvVSWALEKLELSKYADMP------AGT 180
Cdd:COG4178  419 --------RIARPAGARVLF--LPQRPYLPLGT-LREAllypataeAFSDAE--LREALEAVGLGHLAERLdeeadwDQV 485

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 181 YSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKtGRSVVLTSH 238
Cdd:COG4178  486 LSLGEQQRLAFARLLLHKPDWLFLDEATSALDEENEAALYQLLREELP-GTTVISVGH 542
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
64-238 8.45e-07

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 49.57  E-value: 8.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKELLRvqQSIGYCPQfDALFEDLTAR 140
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGtdiRTVTRASLR--RNIAVVFQ-DAGLFNRSIE 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 141 EHLELytrlrGIPWKDEERVVSwALEKLELSKYADMPAGTY-----------SGGNKRKLSTAIALIGYPSLVFLDEPTT 209
Cdd:PRK13657 427 DNIRV-----GRPDATDEEMRA-AAERAQAHDFIERKPDGYdtvvgergrqlSGGERQRLAIARALLKDPPILILDEATS 500

                        170       180
                 ....*....|....*....|....*....
gi 641957197 210 GMDPKARRFLwNLILDILKTGRSVVLTSH 238
Cdd:PRK13657 501 ALDVETEAKV-KAALDELMKGRTTFIIAH 528
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
 68-244 9.52e-07

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 49.72  E-value: 9.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   68 LCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK-ELLRVQQSIGYCPQFDALFEDlTAREHLely 146
Cdd:TIGR00958 500 LTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDGVPLVQyDHHYLHRQVALVGQEPVLFSG-SVRENI--- 575

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  147 trLRGIPWKDEERVVSWALEKLELSKYADMPAGTY----------SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKAR 216
Cdd:TIGR00958 576 --AYGLTDTPDEEIMAAAKAANAHDFIMEFPNGYDtevgekgsqlSGGQKQRIAIARALVRKPRVLILDEATSALDAECE 653

                         170       180
                  ....*....|....*....|....*...
gi 641957197  217 RFLWNlilDILKTGRSVVLTSHSMEECE 244
Cdd:TIGR00958 654 QLLQE---SRSRASRTVLLIAHRLSTVE 678
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
 64-258 9.89e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 49.34  E-value: 9.89e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG----------------SSILKELLRVQQS---- 123
Cdd:PRK10982  13 ALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGkeidfksskealengiSMVHQELNLVLQRsvmd 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 ---IGYCPQfDALFEDltareHLELYTRLRGIpwkdeervvswaLEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPS 200
Cdd:PRK10982  93 nmwLGRYPT-KGMFVD-----QDKMYRDTKAI------------FDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAK 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 641957197 201 LVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVNGRF 258
Cdd:PRK10982 155 IVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEITILRDGQW 212
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
 45-242 1.70e-06

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 48.11  E-value: 1.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSRKMgrilaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLT------GDESTTGGEAFIGGSSILKEL- 117
Cdd:PRK14258   8 IKVNNLSFYYDTQKI-----LEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNrmneleSEVRVEGRVEFFNQNIYERRVn 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 118 ---LRVQQSIGYcPQFDaLFEdLTAREHLELYTRLRGIPWKDE-ERVVSWALEKLEL----SKYADMPAGTYSGGNKRKL 189
Cdd:PRK14258  83 lnrLRRQVSMVH-PKPN-LFP-MSVYDNVAYGVKIVGWRPKLEiDDIVESALKDADLwdeiKHKIHKSALDLSGGQQQRL 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 190 STAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDI-LKTGRSVVLTSHSMEE 242
Cdd:PRK14258 160 CIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLrLRSELTMVIVSHNLHQ 213
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
 64-238 3.84e-06

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 46.84  E-value: 3.84e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  64 AVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSI----LKELLRvqqSIGYCPQFDALFEDlTA 139
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVrdytLASLRR---QIGLVSQDVFLFND-TV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 140 REHLeLYtrlrGIPWKDEERVVSwALEKLELSKYAD-MPAG----------TYSGGNKRKLSTAIALIGYPSLVFLDEPT 208
Cdd:cd03251   93 AENI-AY----GRPGATREEVEE-AARAANAHEFIMeLPEGydtvigergvKLSGGQRQRIAIARALLKDPPILILDEAT 166

                        170       180       190
                 ....*....|....*....|....*....|...
gi 641957197 209 TGMDPKARRflwnLI---LDILKTGRSVVLTSH 238
Cdd:cd03251  167 SALDTESER----LVqaaLERLMKNRTTFVIAH 195
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
 60-239 5.70e-06

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 45.61  E-value: 5.70e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  60 GRILaVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGD-ESTTGgeafiggssilkellrvqqSIGYCPQFDALFedLT 138
Cdd:cd03223   13 GRVL-LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLwPWGSG-------------------RIGMPEGEDLLF--LP 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 139 AREHLELYTrLRGI---PWKDEervvswaleklelskyadmpagtYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKA 215
Cdd:cd03223   71 QRPYLPLGT-LREQliyPWDDV-----------------------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEES 126

                        170       180
                 ....*....|....*....|....
gi 641957197 216 RRFLWNLILDILKTgrsVVLTSHS 239
Cdd:cd03223  127 EDRLYQLLKELGIT---VISVGHR 147
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
 49-212 6.24e-06

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 47.04  E-value: 6.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  49 NLTKVYKSRKmgRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAfiggssilkellRVQQ--SIGY 126
Cdd:PRK11819  11 RVSKVVPPKK--QIL--KDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEA------------RPAPgiKVGY 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 127 CPQFDALFEDLTAREHLE--------LYTRLRGI------PWKD-----------EERVVS---WALE-KLELSKYA--- 174
Cdd:PRK11819  75 LPQEPQLDPEKTVRENVEegvaevkaALDRFNEIyaayaePDADfdalaaeqgelQEIIDAadaWDLDsQLEIAMDAlrc 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 641957197 175 ---DMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:PRK11819 155 ppwDAKVTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
 61-255 6.82e-06

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 46.93  E-value: 6.82e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  61 RILAVDRLCLgvRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGE---AFIGGSSILKELLrvQQSIGYCPQ---FDALF 134
Cdd:PRK10938  17 KTLQLPSLTL--NAGDSWAFVGANGSGKSALARALAGELPLLSGErqsQFSHITRLSFEQL--QKLVSDEWQrnnTDMLS 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 135 ED-----LTAREHLELYTrlrgipwKDEERVVSWAlEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTT 209
Cdd:PRK10938  93 PGeddtgRTTAEIIQDEV-------KDPARCEQLA-QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFD 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 641957197 210 GMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMVN 255
Cdd:PRK10938 165 GLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPDFVQFAGVLAD 210
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
72-238 6.92e-06

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 47.11  E-value: 6.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  72 VRPGECFGLLGVNGAGKTTTFKMLTG--------DESTTGGEAFI---GGSSI---LKEL----LRVQQSIGYCPQFDAL 133
Cdd:PRK13409  96 PKEGKVTGILGPNGIGKTTAVKILSGelipnlgdYEEEPSWDEVLkrfRGTELqnyFKKLyngeIKVVHKPQYVDLIPKV 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 134 FeDLTAREHLELYtrlrgipwkDEERVVSWALEKLELSKYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDP 213
Cdd:PRK13409 176 F-KGKVRELLKKV---------DERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDI 245

                        170       180
                 ....*....|....*....|....*
gi 641957197 214 KARRFLWNLILDILKtGRSVVLTSH 238
Cdd:PRK13409 246 RQRLNVARLIRELAE-GKYVLVVEH 269
nikD PRK10418
nickel transporter ATP-binding protein NikD; Provisional
 65-257 8.12e-06

nickel transporter ATP-binding protein NikD; Provisional


Pssm-ID: 236688 [Multi-domain]  Cd Length: 254  Bit Score: 45.85  E-value: 8.12e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  65 VDRLCLGVRPGECFGLLGVNGAGKTTT----FKMLTGDESTTGGEAFIGGSSILKELLR------VQQSigycPQ--FDA 132
Cdd:PRK10418  19 VHGVSLTLQRGRVLALVGGSGSGKSLTcaaaLGILPAGVRQTAGRVLLDGKPVAPCALRgrkiatIMQN----PRsaFNP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 133 LfedLTAREHLELYTRLRGIPwkDEERVVSWALEKLELS---KYADMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTT 209
Cdd:PRK10418  95 L---HTMHTHARETCLALGKP--ADDATLTAALEAVGLEnaaRVLKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTT 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 641957197 210 GMDPKAR-RFLwNLILDILKT-GRSVVLTSHSMEECEALCTRLGIMVNGR 257
Cdd:PRK10418 170 DLDVVAQaRIL-DLLESIVQKrALGMLLVTHDMGVVARLADDVAVMSHGR 218
PLN03073 PLN03073
ABC transporter F family; Provisional
 75-241 1.01e-05

ABC transporter F family; Provisional


Pssm-ID: 215558 [Multi-domain]  Cd Length: 718  Bit Score: 46.39  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  75 GECFGLLGVNGAGKTTTFKMLT---------------------GDESTTGG---EAFIGGSSILKELLRVQQ-------- 122
Cdd:PLN03073 203 GRHYGLVGRNGTGKTTFLRYMAmhaidgipkncqilhveqevvGDDTTALQcvlNTDIERTQLLEEEAQLVAqqrelefe 282

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 123 ---SIGYCPQFDALFEDLTAREHLELYTRLRGIPWKDEERVVSWALEKLELSkyADM---PAGTYSGGNKRKLSTAIALI 196
Cdd:PLN03073 283 tetGKGKGANKDGVDKDAVSQRLEEIYKRLELIDAYTAEARAASILAGLSFT--PEMqvkATKTFSGGWRMRIALARALF 360

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 641957197 197 GYPSLVFLDEPTTGMDPKArrFLWnLILDILKTGRSVVLTSHSME 241
Cdd:PLN03073 361 IEPDLLLLDEPTNHLDLHA--VLW-LETYLLKWPKTFIVVSHARE 402
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
 65-269 1.10e-05

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 45.62  E-value: 1.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  65 VDRLCLGVRPGECFGLLGVNGAGKTTTF----KMLtgdesTTGGEAFIGGSSILK-ELLRVQQSIGYCPQFDALFEDlTA 139
Cdd:cd03289   20 LENISFSISPGQRVGLLGRTGSGKSTLLsaflRLL-----NTEGDIQIDGVSWNSvPLQKWRKAFGVIPQKVFIFSG-TF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 140 REHLELYTRlrgipWKDEE--RVVSWALEKLELSKYAD-----MPAGTY--SGGNKRKLSTAIALIGYPSLVFLDEPTTG 210
Cdd:cd03289   94 RKNLDPYGK-----WSDEEiwKVAEEVGLKSVIEQFPGqldfvLVDGGCvlSHGHKQLMCLARSVLSKAKILLLDEPSAH 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 641957197 211 MDPkarrFLWNLILDILK---TGRSVVLTSHSMeecEAL--CTRLGIMVNGRFKCLGSIQHLKN 269
Cdd:cd03289  169 LDP----ITYQVIRKTLKqafADCTVILSEHRI---EAMleCQRFLVIEENKVRQYDSIQKLLN 225
GguA NF040905
sugar ABC transporter ATP-binding protein;
175-258 1.21e-05

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 45.94  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 175 DMPAGTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSMEECEALCTRLGIMV 254
Cdd:NF040905 399 FQKVGNLSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVMN 478


                 ....
gi 641957197 255 NGRF 258
Cdd:NF040905 479 EGRI 482
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
 182-238 1.74e-05

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 43.89  E-value: 1.74e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 182 SGGNKRKLSTAIAL----IGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:cd03227   79 SGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQVIVITH 139
ycf16 CHL00131
sulfate ABC transporter protein; Validated
 44-238 2.35e-05

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 44.63  E-value: 2.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmgrILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG--DESTTGGEAFIGGSSILKEL--LR 119
Cdd:CHL00131   7 ILEIKNLHASVNENE---IL--KGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGhpAYKILEGDILFKGESILDLEpeER 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 VQQSIGYCPQFDALFEDLTAREHLEL-YT---RLRGIPWKDEERVVSWALEKLELskyADMPAG--------TYSGGNKR 187
Cdd:CHL00131  82 AHLGIFLAFQYPIEIPGVSNADFLRLaYNskrKFQGLPELDPLEFLEIINEKLKL---VGMDPSflsrnvneGFSGGEKK 158

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 641957197 188 K---LSTAIAligYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:CHL00131 159 RneiLQMALL---DSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITH 209
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
 68-238 2.37e-05

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 44.54  E-value: 2.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  68 LCLGVRPGECFGLLGVNGAGKTTTFKMLTGdeSTTG-GEAFIGGSSI----LKELLRVQqsiGY-CPQFDALFEdLTARE 141
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAG--LLPGsGSIQFAGQPLeawsAAELARHR---AYlSQQQTPPFA-MPVFQ 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 142 HLELYtRLRGIPWKDEERVVSWALEKLELSKYADMPAGTYSGGN-KRKLSTAIALIGYPS------LVFLDEPTTGMDPK 214
Cdd:PRK03695  89 YLTLH-QPDKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEwQRVRLAAVVLQVWPDinpagqLLLLDEPMNSLDVA 167

                        170       180
                 ....*....|....*....|....
gi 641957197 215 ARRFLWNLILDILKTGRSVVLTSH 238
Cdd:PRK03695 168 QQAALDRLLSELCQQGIAVVMSSH 191
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
 45-212 2.46e-05

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 44.33  E-value: 2.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  45 LKIDNLTKVYKSrKMGRILavDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK-ELLRVQQS 123
Cdd:cd03369    7 IEVENLSVRYAP-DLPPVL--KNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTiPLEDLRSS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALFeDLTAREHLELYTRlrgipWKDEErvvswALEKLELSKYADmpagTYSGGNKRKLSTAIALIGYPSLVF 203
Cdd:cd03369   84 LTIIPQDPTLF-SGTIRSNLDPFDE-----YSDEE-----IYGALRVSEGGL----NLSQGQRQLLCLARALLKRPRVLV 148


                 ....*....
gi 641957197 204 LDEPTTGMD 212
Cdd:cd03369  149 LDEATASID 157
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
44-257 3.46e-05

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 44.41  E-value: 3.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKmGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGdesttggeafiggssILKELLRVQQS 123
Cdd:PRK15093   3 LLDIRNLTIEFKTSD-GWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICG---------------VTKDNWRVTAD 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 124 IGYCPQFDALfeDLTAREHLELYTR-----------------------LRGIP-WKDEER---VVSW----ALEKLELSK 172
Cdd:PRK15093  67 RMRFDDIDLL--RLSPRERRKLVGHnvsmifqepqscldpservgrqlMQNIPgWTYKGRwwqRFGWrkrrAIELLHRVG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 173 YAD----MPAGTY--SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILK-TGRSVVLTSHSMEECEA 245
Cdd:PRK15093 145 IKDhkdaMRSFPYelTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQnNNTTILLISHDLQMLSQ 224

                        250
                 ....*....|..
gi 641957197 246 LCTRLGIMVNGR 257
Cdd:PRK15093 225 WADKINVLYCGQ 236
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
47-212 3.57e-05

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 44.71  E-value: 3.57e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  47 IDNLTKVYKSRKmgriLAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGG---SSILKELLR---- 119
Cdd:PRK10790 343 IDNVSFAYRDDN----LVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGrplSSLSHSVLRqgva 418

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 -VQQSigycPQF--DALFEDLTAREHLelytrlrgipwkDEERVvsW-ALEKLELSKYA-DMPAGTY----------SGG 184
Cdd:PRK10790 419 mVQQD----PVVlaDTFLANVTLGRDI------------SEEQV--WqALETVQLAELArSLPDGLYtplgeqgnnlSVG 480

                        170       180
                 ....*....|....*....|....*...
gi 641957197 185 NKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:PRK10790 481 QKQLLALARVLVQTPQILILDEATANID 508
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
 44-257 4.46e-05

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 44.31  E-value: 4.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMGRiLAVDRLCLGVRPGECFGLLGVNGAGKTTT----FKML-TGDESTTGGEAFIGGSSILK--- 115
Cdd:PRK15134   5 LLAIENLSVAFRQQQTVR-TVVNDVSLQIEAGETLALVGESGSGKSVTalsiLRLLpSPPVVYPSGDIRFHGESLLHase 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 116 -ELLRVQQSigycpQFDALFEDLTAR------------EHLELYTRLRGIPWKDE-----ERV-VSWALEKLelskyADM 176
Cdd:PRK15134  84 qTLRGVRGN-----KIAMIFQEPMVSlnplhtlekqlyEVLSLHRGMRREAARGEilnclDRVgIRQAAKRL-----TDY 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 177 PAgTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRflwnLILDILKT-----GRSVVLTSHSMEECEALCTRLG 251
Cdd:PRK15134 154 PH-QLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQA----QILQLLRElqqelNMGLLFITHNLSIVRKLADRVA 228


                 ....*.
gi 641957197 252 IMVNGR 257
Cdd:PRK15134 229 VMQNGR 234
SapD COG4170
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
44-270 1.52e-04

ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];


Pssm-ID: 443330 [Multi-domain]  Cd Length: 331  Bit Score: 42.59  E-value: 1.52e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSrKMGRILAVDRLCLGVRPGECFGLLGVNGAGKTTTFKMLTG--DEST--TGGEAFIGGssilKELLR 119
Cdd:COG4170    3 LLDIRNLTIEIDT-PQGRVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGitKDNWhvTADRFRWNG----IDLLK 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 120 ---------VQQSIGYCPQ------------FDALFEDLTAREhlelytrLRGIPWK----DEERVVSWaLEKLELSKYA 174
Cdd:COG4170   78 lsprerrkiIGREIAMIFQepsscldpsakiGDQLIEAIPSWT-------FKGKWWQrfkwRKKRAIEL-LHRVGIKDHK 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 175 D-MPAGTY--SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKT-GRSVVLTSHSMEECEALCTRL 250
Cdd:COG4170  150 DiMNSYPHelTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQLqGTSILLISHDLESISQWADTI 229

                        250       260
                 ....*....|....*....|
gi 641957197 251 GIMVNGRFKCLGSIQHLKNR 270
Cdd:COG4170  230 TVLYCGQTVESGPTEQILKS 249
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
 155-238 1.72e-04

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 42.71  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  155 KDEERVVSWA-----LEKLElSKYaDMPAGTY----SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILD 225
Cdd:PTZ00265 1326 EDVKRACKFAaidefIESLP-NKY-DTNVGPYgkslSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVD 1403

                          90
                  ....*....|....
gi 641957197  226 IL-KTGRSVVLTSH 238
Cdd:PTZ00265 1404 IKdKADKTIITIAH 1417
COG4938 COG4938
Predicted ATPase [General function prediction only];
80-239 1.74e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443965 [Multi-domain]  Cd Length: 277  Bit Score: 42.26  E-value: 1.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  80 LLGVNGAGKTTTFKMLTGDESTTGgeAFIGGS-----SILKELLRVQQSIGYCPQFDALFedltarehLELYTRLRGIPW 154
Cdd:COG4938   25 LIGPNGSGKSTLIQALLLLLQSNF--IYLPAErsgpaRLYPSLVRELSDLGSRGEYTADF--------LAELENLEILDD 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 155 KDE---ERVVSWaLEKLELSKY---ADMPAG-----TYSGGNKRKLS-------------TAIALIGYP-SLVFLDEPTT 209
Cdd:COG4938   95 KSKellEQVEEW-LEKIFPGKVevdASSDLVrlvfrPSGNGKRIPLSnvgsgvsellpilLALLSAAKPgSLLIIEEPEA 173

                        170       180       190
                 ....*....|....*....|....*....|
gi 641957197 210 GMDPKARRFLWNLILDILKTGRSVVLTSHS 239
Cdd:COG4938  174 HLHPKAQSALAELLAELANSGVQVIIETHS 203
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
 177-239 1.78e-04

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 41.15  E-value: 1.78e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 641957197 177 PAGTYSGGNKR--KLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHS 239
Cdd:cd03238   84 KLSTLSGGELQrvKLASELFSEPPGTLFILDEPSTGLHQQDINQLLEVIKGLIDLGNTVILIEHN 148
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
 44-238 1.96e-04

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 41.70  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  44 MLKIDNLTKVYKSRKMGRILAVDrlclgVRPGECFGLLGVNGAGKTTTFKMLTGDE--STTGGEAFIGGSSILKELLRVQ 121
Cdd:PRK09580   1 MLSIKDLHVSVEDKAILRGLNLE-----VRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELSPEDR 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 122 QSIGYCPQFDALFEDLTAREHLELYTRL------RGIPWKDEERVVSWALEKLELSKyadMPAGT--------YSGGNKR 187
Cdd:PRK09580  76 AGEGIFMAFQYPVEIPGVSNQFFLQTALnavrsyRGQEPLDRFDFQDLMEEKIALLK---MPEDLltrsvnvgFSGGEKK 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 641957197 188 KLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:PRK09580 153 RNDILQMAVLEPELCILDESDSGLDIDALKIVADGVNSLRDGKRSFIIVTH 203
PLN03232 PLN03232
ABC transporter C family member; Provisional
 68-212 3.71e-04

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 41.89  E-value: 3.71e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197   68 LCLGVRPGECFGLLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILK-ELLRVQQSIGYCPQFDALFEDlTAREHLELY 146
Cdd:PLN03232 1255 LSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKfGLTDLRRVLSIIPQSPVLFSG-TVRFNIDPF 1333

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  147 TRLRGIP-WKDEERV-VSWALEKLELSKYADMPAG--TYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD 212
Cdd:PLN03232 1334 SEHNDADlWEALERAhIKDVIDRNPFGLDAEVSEGgeNFSVGQRQLLSLARALLRRSKILVLDEATASVD 1403
PRK00635 PRK00635
excinuclease ABC subunit A; Provisional
 162-240 5.79e-04

excinuclease ABC subunit A; Provisional


Pssm-ID: 234806 [Multi-domain]  Cd Length: 1809  Bit Score: 41.35  E-value: 5.79e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  162 SWALEKLELSKyadmPAGTYSGGNKRKLSTAIALIG---YPSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSH 238
Cdd:PRK00635  795 SLGLDYLPLGR----PLSSLSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEH 870


                  ..
gi 641957197  239 SM 240
Cdd:PRK00635  871 NM 872
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
80-264 1.22e-03

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 39.86  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197  80 LLGVNGAGKTTTFKMLTGDESTTGGEAFIGGSSILKELLRV-----QQSIGYCPQfDA-LFEDLTAREHLeLYtrlrGIP 153
Cdd:PRK11144  29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDAEKGIclppeKRRIGYVFQ-DArLFPHYKVRGNL-RY----GMA 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 641957197 154 WKDEE---RVVSW-ALEKLeLSKYadmPAgTYSGGNKRKLSTAIALIGYPSLVFLDEPTTGMD-PKARR---FLWNLILD 225
Cdd:PRK11144 103 KSMVAqfdKIVALlGIEPL-LDRY---PG-SLSGGEKQRVAIGRALLTAPELLLMDEPLASLDlPRKREllpYLERLARE 177

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 641957197 226 IlKTgrSVVLTSHSMEECEALCTRLGIMVNGRFKCLGSI 264
Cdd:PRK11144 178 I-NI--PILYVSHSLDEILRLADRVVVLEQGKVKAFGPL 213
YbjD COG3593
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ...
 199-241 1.67e-03

Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];


Pssm-ID: 442812 [Multi-domain]  Cd Length: 359  Bit Score: 39.22  E-value: 1.67e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 641957197 199 PSLVFLDEPTTGMDPKARRFLWNLILDILKTGRSVVLTSHSME 241
Cdd:COG3593  188 NPILLIEEPEAHLHPQAQRRLLKLLKELSEKPNQVIITTHSPH 230
PRK14243 PRK14243
phosphate transporter ATP-binding protein; Provisional
 182-242 5.35e-03

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184588 [Multi-domain]  Cd Length: 264  Bit Score: 37.45  E-value: 5.35e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 641957197 182 SGGNKRKLSTAIALIGYPSLVFLDEPTTGMDPKARRFLWNLILDiLKTGRSVVLTSHSMEE 242
Cdd:PRK14243 153 SGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHE-LKEQYTIIIVTHNMQQ 212
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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