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Conserved domains on  [gi|146345956|gb|EDK32492|]
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Predicted Na+/H+-dicarboxylate symporter [Clostridium kluyveri DSM 555]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
8-404 7.97e-96

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 293.17  E-value: 7.97e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   8 YKFSIVLLGSIIIGAILGIFLG-HKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTA 86
Cdd:COG1301    3 LSLTLQILIALVLGILLGLLLPeLVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKTLLYFLVTT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  87 LAASIIGIIGVFIVEPAKGIDymalkqIVSGSNDSLQQVKHVGVFQQIVNtITVSEFTSLFSKSNMLQLIVFSVLFGIST 166
Cdd:COG1301   83 TIALVIGLVVANLFQPGAGLN------LDLADAAAAEAAEAPSLLDFLLN-IIPSNIFEAFAEGNMLQIIFFAILFGIAL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 167 AALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGFFTLYAFL 246
Cdd:COG1301  156 AALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLHLFVVLPLILRL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 247 AGGKNAIKiFWKNAAVPTITALATCSSAASIPVNLE-FTKKMGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLLN 325
Cdd:COG1301  236 LTGLSPLK-FLRAIRPALLLAFSTSSSEATLPVTMEkAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYG 314

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146345956 326 KNMaSISSVLSIIFISFLVGAVMAAIPSGGMIGEMLILSIYGFSQGLLPIIMVISVIIDAPATVLNSTGNTVCSMMISR 404
Cdd:COG1301  315 IDL-SLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
8-404 7.97e-96

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 293.17  E-value: 7.97e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   8 YKFSIVLLGSIIIGAILGIFLG-HKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTA 86
Cdd:COG1301    3 LSLTLQILIALVLGILLGLLLPeLVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKTLLYFLVTT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  87 LAASIIGIIGVFIVEPAKGIDymalkqIVSGSNDSLQQVKHVGVFQQIVNtITVSEFTSLFSKSNMLQLIVFSVLFGIST 166
Cdd:COG1301   83 TIALVIGLVVANLFQPGAGLN------LDLADAAAAEAAEAPSLLDFLLN-IIPSNIFEAFAEGNMLQIIFFAILFGIAL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 167 AALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGFFTLYAFL 246
Cdd:COG1301  156 AALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLHLFVVLPLILRL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 247 AGGKNAIKiFWKNAAVPTITALATCSSAASIPVNLE-FTKKMGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLLN 325
Cdd:COG1301  236 LTGLSPLK-FLRAIRPALLLAFSTSSSEATLPVTMEkAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYG 314

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146345956 326 KNMaSISSVLSIIFISFLVGAVMAAIPSGGMIGEMLILSIYGFSQGLLPIIMVISVIIDAPATVLNSTGNTVCSMMISR 404
Cdd:COG1301  315 IDL-SLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
14-405 1.82e-87

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 270.93  E-value: 1.82e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   14 LLGSIIIGAILGIFLGHKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTALAASIIG 93
Cdd:pfam00375   5 ILIALVLGILIGLFFPELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLYFLVTTAIAALIG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   94 IIGVFIVEPAKGIDymalkqiVSGSNDSLQQVKHVGVFQQIVNTITVSEFTSLFSKSNMLQLIVFSVLFGISTAALGEKA 173
Cdd:pfam00375  85 LLVANVFQPGSGLA-------LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEGNVLAVIVFAILFGIALAALGEKG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  174 ETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGFFTLYAFLAGGKNAI 253
Cdd:pfam00375 158 EPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  254 KiFWKNAAVPTITALATCSSAASIPVNLEFTKK-MGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLLNKNMaSIS 332
Cdd:pfam00375 238 K-FLKKMLPALLTAFSTASSAATLPVTLECAEKnLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDL-SFG 315

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146345956  333 SVLSIIFISFLVGAVMAAIPSGGMIGEMLILSIYGFSQGLLPIIMVISVIIDAPATVLNSTGNTVCSMMISRL 405
Cdd:pfam00375 316 QQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 18-365 2.58e-29

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 118.47  E-value: 2.58e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  18 IIIGAILGIFLGHKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTALAASIIGIIGV 97
Cdd:PRK01663  17 IIIGILLGHFYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMGDMKKVGRVGGKALLYFEIVSTIALIIGLIVV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  98 FIVEPAKG--IDYMALKQ-IVSGSNDSLQQVKHVGVFQQIVNTITVSEftslFSKSNMLQLIVFSVLFGISTAALGEKAE 174
Cdd:PRK01663  97 NVVQPGAGmnIDPATLDAkAVAQYAAQAHEQGTVDFLMDIIPTTVVGA----FASGDILQVLLFAVLFGFALARLGEKGK 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 175 TVTKFFTAASRVMMEMVRIIMYYAPIG--------LGCYFASVIGELGPQILQGYLK--VFILYIIISIIYYFGfFTLYA 244
Cdd:PRK01663 173 PVFDFIESLSHVLFGIVNMIMKLAPIGafgamaftIGKYGVGSLVQLGQLIGCFYITciLFVFVVLGAIARLTG-FSIFK 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 245 FLAGGKNAIKIfwknaavptitALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLL 324
Cdd:PRK01663 252 FIRYIKEELLI-----------VLGTSSSESALPRMMEKMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQAT 320

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 146345956 325 NKNMaSISSVLSIIFISFL---------------VGAVMAAIPSGGMIGEMLILSI 365
Cdd:PRK01663 321 NTPL-SIGHQITLLAVLLLtskgaagvtgsgfivLAATLSAVPHIPVAGLALILGI 375
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
8-404 7.97e-96

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 293.17  E-value: 7.97e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   8 YKFSIVLLGSIIIGAILGIFLG-HKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTA 86
Cdd:COG1301    3 LSLTLQILIALVLGILLGLLLPeLVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKTLLYFLVTT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  87 LAASIIGIIGVFIVEPAKGIDymalkqIVSGSNDSLQQVKHVGVFQQIVNtITVSEFTSLFSKSNMLQLIVFSVLFGIST 166
Cdd:COG1301   83 TIALVIGLVVANLFQPGAGLN------LDLADAAAAEAAEAPSLLDFLLN-IIPSNIFEAFAEGNMLQIIFFAILFGIAL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 167 AALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGFFTLYAFL 246
Cdd:COG1301  156 AALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLHLFVVLPLILRL 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 247 AGGKNAIKiFWKNAAVPTITALATCSSAASIPVNLE-FTKKMGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLLN 325
Cdd:COG1301  236 LTGLSPLK-FLRAIRPALLLAFSTSSSEATLPVTMEkAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYG 314

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 146345956 326 KNMaSISSVLSIIFISFLVGAVMAAIPSGGMIGEMLILSIYGFSQGLLPIIMVISVIIDAPATVLNSTGNTVCSMMISR 404
Cdd:COG1301  315 IDL-SLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
14-405 1.82e-87

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 270.93  E-value: 1.82e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   14 LLGSIIIGAILGIFLGHKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTALAASIIG 93
Cdd:pfam00375   5 ILIALVLGILIGLFFPELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLYFLVTTAIAALIG 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   94 IIGVFIVEPAKGIDymalkqiVSGSNDSLQQVKHVGVFQQIVNTITVSEFTSLFSKSNMLQLIVFSVLFGISTAALGEKA 173
Cdd:pfam00375  85 LLVANVFQPGSGLA-------LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEGNVLAVIVFAILFGIALAALGEKG 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  174 ETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGFFTLYAFLAGGKNAI 253
Cdd:pfam00375 158 EPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPF 237

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  254 KiFWKNAAVPTITALATCSSAASIPVNLEFTKK-MGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLLNKNMaSIS 332
Cdd:pfam00375 238 K-FLKKMLPALLTAFSTASSAATLPVTLECAEKnLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDL-SFG 315

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 146345956  333 SVLSIIFISFLVGAVMAAIPSGGMIGEMLILSIYGFSQGLLPIIMVISVIIDAPATVLNSTGNTVCSMMISRL 405
Cdd:pfam00375 316 QQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 18-365 2.58e-29

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 118.47  E-value: 2.58e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  18 IIIGAILGIFLGHKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFIVFLFTALAASIIGIIGV 97
Cdd:PRK01663  17 IIIGILLGHFYPELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMGDMKKVGRVGGKALLYFEIVSTIALIIGLIVV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  98 FIVEPAKG--IDYMALKQ-IVSGSNDSLQQVKHVGVFQQIVNTITVSEftslFSKSNMLQLIVFSVLFGISTAALGEKAE 174
Cdd:PRK01663  97 NVVQPGAGmnIDPATLDAkAVAQYAAQAHEQGTVDFLMDIIPTTVVGA----FASGDILQVLLFAVLFGFALARLGEKGK 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 175 TVTKFFTAASRVMMEMVRIIMYYAPIG--------LGCYFASVIGELGPQILQGYLK--VFILYIIISIIYYFGfFTLYA 244
Cdd:PRK01663 173 PVFDFIESLSHVLFGIVNMIMKLAPIGafgamaftIGKYGVGSLVQLGQLIGCFYITciLFVFVVLGAIARLTG-FSIFK 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 245 FLAGGKNAIKIfwknaavptitALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHKDGSVIGGVMKIAFLFGLL 324
Cdd:PRK01663 252 FIRYIKEELLI-----------VLGTSSSESALPRMMEKMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQAT 320

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 146345956 325 NKNMaSISSVLSIIFISFL---------------VGAVMAAIPSGGMIGEMLILSI 365
Cdd:PRK01663 321 NTPL-SIGHQITLLAVLLLtskgaagvtgsgfivLAATLSAVPHIPVAGLALILGI 375
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 1-368 3.21e-24

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 103.60  E-value: 3.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   1 MKKFLGGYKFSIVLlgSIIIGAILGIFLGHKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIGSTFI 80
Cdd:PRK13027   1 MKKFLRSLFGQVVI--ALVLGVALGAFFPHFAESLKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAGDLKKVGRVGLKAVI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  81 VFLFTALAASIIGIIGVFIVEPAKG--IDYMALK-QIVSGSNDSLQQVKHVGVFqqIVNTITVSeFTSLFSKSNMLQLIV 157
Cdd:PRK13027  79 YFEVMTTIALVIGLVLAYLTGPGVGmnIDLRSLDaASLAGYAKNAQSLKGTAGF--LLKLIPTT-AVDAFAKGDILQVLL 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 158 FSVLFGISTAALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYF 237
Cdd:PRK13027 156 FSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAFTTGKYGVGSLKQLGMLVAVFYLTCFVFVV 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 238 GFFTLYAFLAGGK--NAIKIFWKNAAVptitALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHKDGSVIGGVM 315
Cdd:PRK13027 236 VVLGAVMRLAGFSvfKLIRYLREELLI----VLGTASSDAVLPQVMRKLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTL 311

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 146345956 316 KIAFLFGLLNKNMaSISSVLSIIFISFL---------------VGAVMAAIPSGGMIGEMLILSIYGF 368
Cdd:PRK13027 312 AAVFIAQATNTPL-SMHDLITILLVSLVtskgahgipgsaiviLAATLSAIPAIPVLGLVLILPVDWF 378
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 9-404 6.54e-22

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 97.14  E-value: 6.54e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   9 KFSIVLLGSIIIGAILGIFLGHK------------ASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKIIG 76
Cdd:PRK11283   3 NIKFSLAWQILIALVLGILLGAYlhyhsdsrdwlvSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGA 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  77 STFIVFLFTALAASIIGIIGVFIVEPAKGIDYMALKQI-VSGSNDSLQQVKH--VGVFQQIVNTITVSEFTSLfSKSNML 153
Cdd:PRK11283  83 KTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVdISKYQSTTEEVQShsHGLMGTILSLIPTNIFASM-AKGEML 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 154 QLIVFSVLFGISTAALGEKA-ETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIIS 232
Cdd:PRK11283 162 PIIFFSVLFGLGLSSLPATHrEPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFAI 241

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 233 IIYYFGFFTLYAFLAGGK--NAIKIFWKNaavpTITALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHKDGSV 310
Cdd:PRK11283 242 LFFALVVLGIVARLCGLSiwILIRILKDE----LILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGST 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 311 IGGVMKIAFLFGLLNKNMaSISSVLSIIFISFLVGAVMAAIPSGGMIGEMLILSIYGFSQGLLPIIMVISVIIDAPATVL 390
Cdd:PRK11283 318 LYQSIAAIFIAQLYGIDL-SIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTAL 396

                        410
                 ....*....|....
gi 146345956 391 NSTGNTVCSMMISR 404
Cdd:PRK11283 397 NVVGNALAVLVIAK 410
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 14-311 9.07e-15

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 75.29  E-value: 9.07e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  14 LLGSIIIGAILGIFLG----HKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMK-GMK-RFGKIIgstfIVFLFTAL 87
Cdd:PRK13628  16 LVKQILIGLVLGILLAllspPAAEAVGLLGTLFVGALKAVAPILVFVLVMASIANHKkGQKtNIRPIL----VLYLLGTF 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  88 AASIIgiigvfivepAKGIDYMALKQIV-SGSNDSLQQVKHVG-VFQQIVNTITVSEFTSLFSkSNMLQLIVFSVLFGIs 165
Cdd:PRK13628  92 LAALV----------AVVASFLFPSTLVlVASAADISPPQGIVeVLKTLLLSLVDNPINALLN-ANYIGILAWAIGLGL- 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 166 taALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGFFTLYAF 245
Cdd:PRK13628 160 --ALRHASDTTKNVVNDLSEAVSQIVKWVIRFAPIGIFGLVASTLAETGFSALAGYAQLLAVLVGCMLFVALVVNPLIVF 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 146345956 246 LAGGKNAIKIFWKNAAVPTITALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHKDGSVI 311
Cdd:PRK13628 238 WKIRRNPYPLVFTCLRESGVTAFFTRSSAANIPVNMALCEKLGLDEDTYSVSIPLGATINMAGAAI 303
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 7-290 1.41e-14

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 75.25  E-value: 1.41e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956   7 GYKFSI-VLLG---SIIIGAILGIFLGHKASVLKPF-------GDLFLNLMFMIIIPLVFFSVTSAIANMKGMKRFGKII 75
Cdd:COG1823   27 HVSFSKrVFTGlglGILFGLILQLIYGAGSPVIKQSidwfnivGNGYVRLLQMIVMPLVFVSILSAITKLKNASSLGKIS 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  76 GSTFIVFLFTALAASIIGIIGvfivepAKGIDYMAlKQIVSGS---------NDSLQQVKHVGVFQQIVNTITVSEFTSL 146
Cdd:COG1823  107 GLIIGILLGTTAIAALVGILV------ALLFGLTA-EGLTQGAaetargealEERLGEVEDLSLPQQILSFIPTNPFADL 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 147 --FSKSNMLQLIVFSVLFGIstAALG------EKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQ-I 217
Cdd:COG1823  180 tgARPTSTIAVVIFAAFLGI--AALGlrrkkpEQAETFLKGIDALQAIVMRLVRLVLRLTPYGVLALMTKVVATSDFAdI 257

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 146345956 218 LQgyLKVFILYIIISIIYYFGFFTLYAFLAgGKNAIKIFWKnaAVPTIT-ALATCSSAASIPVNLEF-TKKMGVP 290
Cdd:COG1823  258 LN--LGKFVVASYVALIIMFIVHLLLLALA-GLNPLTYFKK--VWPVLTfAFTSRSSAGTIPLNIETqTKRLGVP 327
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
10-311 2.38e-14

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 74.05  E-value: 2.38e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  10 FSIVLLGSIIIGAILGIFLG----HKASVLKPFGDLFLNLMFMIIIPLVFFSVTSAIANMK-GMK-RFGKIIG----STF 79
Cdd:COG3633   11 NRGSLVKQILIGLVLGILLAllspEAAKSVGLLGTLFVGALKAVAPILVFVLVMSAIANHKqGQKtNMKPIIVlyllGTF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956  80 IVFLfTALAASIIGIIGVFIVEPAKGIDymalkqivsgSNDSLQQVKHVGVFQQIVNTItvseftSLFSKSNMLQLIVFS 159
Cdd:COG3633   91 LAAL-VAVVASFLFPTTLTLVAAAADLT----------PPGGIGEVLKTLLLNVVDNPV------NALANANYIGILAWA 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 160 VLFGIstaALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYIIISIIYYFGF 239
Cdd:COG3633  154 IGLGL---ALRHASDTTKTVLSDLSDAVSKIVRWVIRFAPLGIFGLVASTVATTGFSALLGYAHLLAVLVGCMLFVALVV 230

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 146345956 240 FTLYAFLAGGKNAIKIFWKNAAVPTITALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHKDGSVI 311
Cdd:COG3633  231 NPLIVFLKIRRNPYPLVFTCLRESGITAFFTRSSAANIPVNMALCEKLGLDEDTYSVSIPLGATINMAGAAI 302
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 150-397 1.19e-08

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 56.21  E-value: 1.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 150 SNMLQLIVFSVLFGIstaALGEKAETVTKFFTAASRVMMEMVRIIMYYAPIGLGCYFASVIGELGPQILQGYLKVFILYI 229
Cdd:PRK14695  59 ANYIGILSWAVIFGI---AMREASKNSKELLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSLANYGILLVLLV 135

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 230 IISIIYYFGFFTLYAFLAGGKNAIKIFWKNAAVPTITALATCSSAASIPVNLEFTKKMGVPKDVTETVIPLGANIHkdgs 309
Cdd:PRK14695 136 TTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRVSGVTAFFTRSSATNIPVNMKLCHDLGLNPDTYSVSIPLGSTIN---- 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 146345956 310 vIGGVMKIAFLFGLLNKNMASISSVLSIIFISFLVGAVMAAIPSGGMIGEMLIL----SIYGFSQGL----LPIIMVISV 381
Cdd:PRK14695 212 -MAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIpvacSLFGISNDIaiqiVGVGFVIGV 290

                        250
                 ....*....|....*.
gi 146345956 382 IIDAPATVLNSTGNTV 397
Cdd:PRK14695 291 IQDSCETALNSSTDVL 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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