unnamed protein product [Saccharomyces cerevisiae]
Protein Classification
mRNA transport regulator MTR2( domain architecture ID 10564431)
mRNA transport regulator MTR2 affects mRNA transport from the nucleus to the cytoplasm
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| Mtr2 | pfam10429 | Nuclear pore RNA shuttling protein Mtr2; Mtr2 is a monomeric, dual-action, RNA-shuttle protein ... |
13-184 | 4.30e-101 | ||||
Nuclear pore RNA shuttling protein Mtr2; Mtr2 is a monomeric, dual-action, RNA-shuttle protein found in yeasts. Transport across the nuclear-cytoplasmic membrane is via the macro-molecular membrane-spanning nuclear pore complex, NPC. The pore is lined by a subset of NPC members called nucleoporins that present FG (Phe-Gly) receptors, characteriztically GLFG and FXFG motifs, for shuttling RNAs and proteins. RNA cargo is bound to soluble transport proteins (nuclear export factors) such as Mex67 in yeasts, and TAP in metazoa, which pass along the pore by binding to successive FG receptors. Mtr2 when bound to Mex67 maximizes this FG-binding. Mtr2 also acts independently of Mex67 in transporting the large ribosomal RNA subunit through the pore. : Pssm-ID: 402175 Cd Length: 164 Bit Score: 288.27 E-value: 4.30e-101
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| Name | Accession | Description | Interval | E-value | ||||
| Mtr2 | pfam10429 | Nuclear pore RNA shuttling protein Mtr2; Mtr2 is a monomeric, dual-action, RNA-shuttle protein ... |
13-184 | 4.30e-101 | ||||
Nuclear pore RNA shuttling protein Mtr2; Mtr2 is a monomeric, dual-action, RNA-shuttle protein found in yeasts. Transport across the nuclear-cytoplasmic membrane is via the macro-molecular membrane-spanning nuclear pore complex, NPC. The pore is lined by a subset of NPC members called nucleoporins that present FG (Phe-Gly) receptors, characteriztically GLFG and FXFG motifs, for shuttling RNAs and proteins. RNA cargo is bound to soluble transport proteins (nuclear export factors) such as Mex67 in yeasts, and TAP in metazoa, which pass along the pore by binding to successive FG receptors. Mtr2 when bound to Mex67 maximizes this FG-binding. Mtr2 also acts independently of Mex67 in transporting the large ribosomal RNA subunit through the pore. Pssm-ID: 402175 Cd Length: 164 Bit Score: 288.27 E-value: 4.30e-101
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| Name | Accession | Description | Interval | E-value | ||||
| Mtr2 | pfam10429 | Nuclear pore RNA shuttling protein Mtr2; Mtr2 is a monomeric, dual-action, RNA-shuttle protein ... |
13-184 | 4.30e-101 | ||||
Nuclear pore RNA shuttling protein Mtr2; Mtr2 is a monomeric, dual-action, RNA-shuttle protein found in yeasts. Transport across the nuclear-cytoplasmic membrane is via the macro-molecular membrane-spanning nuclear pore complex, NPC. The pore is lined by a subset of NPC members called nucleoporins that present FG (Phe-Gly) receptors, characteriztically GLFG and FXFG motifs, for shuttling RNAs and proteins. RNA cargo is bound to soluble transport proteins (nuclear export factors) such as Mex67 in yeasts, and TAP in metazoa, which pass along the pore by binding to successive FG receptors. Mtr2 when bound to Mex67 maximizes this FG-binding. Mtr2 also acts independently of Mex67 in transporting the large ribosomal RNA subunit through the pore. Pssm-ID: 402175 Cd Length: 164 Bit Score: 288.27 E-value: 4.30e-101
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| Blast search parameters | ||||
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