NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|350539213|ref|NP_001232607|]
View 

guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [Taeniopygia guttata]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
GGL super family cl00069
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta ...
1-37 2.05e-09

G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors


The actual alignment was detected with superfamily member cd00068:

Pssm-ID: 469600  Cd Length: 57  Bit Score: 46.51  E-value: 2.05e-09
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 350539213  1 MSSKTIPEFVKWIEDGIPEDPFLNPELMKNNPWVEKG 37
Cdd:cd00068  21 KVSKAAAELLKYCEQNAENDPLLTGPPSPSNPWIEKK 57
 
Name Accession Description Interval E-value
GGL cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta ...
1-37 2.05e-09

G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors


Pssm-ID: 238024  Cd Length: 57  Bit Score: 46.51  E-value: 2.05e-09
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 350539213  1 MSSKTIPEFVKWIEDGIPEDPFLNPELMKNNPWVEKG 37
Cdd:cd00068  21 KVSKAAAELLKYCEQNAENDPLLTGPPSPSNPWIEKK 57
G-gamma pfam00631
GGL domain; G-protein gamma like domains (GGL) are found in the gamma subunit of the ...
1-42 2.17e-07

GGL domain; G-protein gamma like domains (GGL) are found in the gamma subunit of the heterotrimeric G protein complex and in regulators of G protein signaling (RGS) proteins. It is also found fused to an inactive Galpha in the Dictyostelium protein gbqA. G-gamma likely shares a common origin with the helical N-terminal unit of G-beta. All organizms that posses a G-beta possess a G-gamma.


Pssm-ID: 459879 [Multi-domain]  Cd Length: 69  Bit Score: 41.95  E-value: 2.17e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 350539213   1 MSSKTIPEFVKWIEDGIPEDPFLNP---ELMKNNPWVEK-GKCIIL 42
Cdd:pfam00631 24 KVSKACEELIDYCEQRSTKDPLLPGvwgPPAGENPWREDdGCCWIL 69
GGL smart00224
G protein gamma subunit-like motifs;
2-42 8.88e-05

G protein gamma subunit-like motifs;


Pssm-ID: 128520  Cd Length: 63  Bit Score: 34.95  E-value: 8.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 350539213    2 SSKTIPEFVKWIEDGIPEDPFLNPELMKNNPWVE-KGKCIIL 42
Cdd:smart00224 22 VSKAAEELLAYCEQHAEEDPLLTGPPPSKNPFIEdKTSCWIL 63
 
Name Accession Description Interval E-value
GGL cd00068
G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta ...
1-37 2.05e-09

G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors


Pssm-ID: 238024  Cd Length: 57  Bit Score: 46.51  E-value: 2.05e-09
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 350539213  1 MSSKTIPEFVKWIEDGIPEDPFLNPELMKNNPWVEKG 37
Cdd:cd00068  21 KVSKAAAELLKYCEQNAENDPLLTGPPSPSNPWIEKK 57
G-gamma pfam00631
GGL domain; G-protein gamma like domains (GGL) are found in the gamma subunit of the ...
1-42 2.17e-07

GGL domain; G-protein gamma like domains (GGL) are found in the gamma subunit of the heterotrimeric G protein complex and in regulators of G protein signaling (RGS) proteins. It is also found fused to an inactive Galpha in the Dictyostelium protein gbqA. G-gamma likely shares a common origin with the helical N-terminal unit of G-beta. All organizms that posses a G-beta possess a G-gamma.


Pssm-ID: 459879 [Multi-domain]  Cd Length: 69  Bit Score: 41.95  E-value: 2.17e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 350539213   1 MSSKTIPEFVKWIEDGIPEDPFLNP---ELMKNNPWVEK-GKCIIL 42
Cdd:pfam00631 24 KVSKACEELIDYCEQRSTKDPLLPGvwgPPAGENPWREDdGCCWIL 69
GGL smart00224
G protein gamma subunit-like motifs;
2-42 8.88e-05

G protein gamma subunit-like motifs;


Pssm-ID: 128520  Cd Length: 63  Bit Score: 34.95  E-value: 8.88e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 350539213    2 SSKTIPEFVKWIEDGIPEDPFLNPELMKNNPWVE-KGKCIIL 42
Cdd:smart00224 22 VSKAAEELLAYCEQHAEEDPLLTGPPPSKNPFIEdKTSCWIL 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH