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Concise Results
Standard Results
Full Results
transcriptional regulator ICP4 [Gallid alphaherpesvirus 3]
Protein Classification
PHA03307 family protein ( domain architecture ID 11476204 )
PHA03307 family protein
List of domain hits
Name
Accession
Description
Interval
E-value
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
873-1992
0e+00
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 918.79
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 873 WNGPS P RPG LV SS PTGTQ ER YRRVQ P G S GSD G SHTTA P P A VLKQALQQ E VGTPA T RA S HPLP R PPPA S YPSLGC RS R S S S 952
Cdd:PHA03307 275 WNGPS S RPG PA SS SSSPR ER SPSPS P S S PGS G PAPSS P R A SSSSSSSR E SSSSS T SS S SESS R GAAV S PGPSPS RS P S P S 354
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 953 SSSASSSS SS SSSA P SS S EQS S AAPS S RTSSRS ptr EAGAPQC A A R G R G R GRG GR RGR GR RA PSP ------ S SETA A PP P 1026
Cdd:PHA03307 355 RPPPPADP SS PRKR P RP S RAP S SPAA S AGRPTR --- RRARAAV A G R A R R R DAT GR FPA GR PR PSP ldagaa S GAFY A RY P 431
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1027 PDDLDQ E V W WQI P S PP A GR CWF G P LG GH R QA L RGI PEV EQ AA V R FLST PGP L PVYV E EMG NC AKQY E ALV SAMLNK D VK A 1106
Cdd:PHA03307 432 LLTPSG E P W PGS P P PP P GR VRY G G LG DS R PG L WDA PEV RE AA A R YEAS PGP V PVYV P EMG DS AKQY A ALV RLLYTP D RE A 511
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1107 NP ln W AHHG KL SPT D A AL NHIYVT KF R s SHSSP G AAV TG T V NKCI PHI AS AM KKR N L LWALPH I AA S V S M T RRY CKD QK E 1186
Cdd:PHA03307 512 MG -- W LQNP KL TGP D Q AL DQFCQK KF Q - APRGS G SFI TG S V ARPV PHI GD AM AAG N A LWALPH A AA A V A M S RRY DRA QK G 588
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1187 F MFR SLR K AYAPMA SAAS A EMRR psaspisnrapvtaqstaaglipvidvstihdrvrrgvaafnsaleeglld VPEYRL 1266
Cdd:PHA03307 589 F LLQ SLR R AYAPMA YPEN A ADTG --------------------------------------------------- AGAAAP 617
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1267 VAP A RPDIP A GD G F AS T RPL N EL V DAC A L E C EG V VA ALL R GPDG PG A vaemlss CEDGP FPRPA GH - EQW E K C R A L L G SW 1345
Cdd:PHA03307 618 APA A PRPDA A AA G G AS A RPL R EL A DAC V L A C RA V LE ALL E GPDG LS A ------- VPGLA FPRPA CP p RAL E A C P A R L E SW 690
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1346 LR D L L DLR S AVY A A YAN G -- SAPR GR Q ER TL A AN A AA L ITEAIG PL LSKD P A R PWRCPGSR DIT SV L LRECGSRG ----- 1418
Cdd:PHA03307 691 LR E L R DLR D AVY L A RLR G dl PVAG GR E ER VA A VR A VS L VARTVA PL VRYS P R R ARARASAW DIT DA L FSNPSLVP aklae 770
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1419 ----------------- E PVR SREKA RR LQ R VA R LLAD ADAAS SGT S EGR SR --------- S AE P CYD PG P A SS P E P V R a 1472
Cdd:PHA03307 771 alallepaepqrgagss P PVR AEAAF RR PG R LR R SGPA ADAAS RTA S KRK SR shtpdggse S SG P ARP PG A A AR P P P A R - 849
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1473 lcaqt S A ES R K R K S A P A AVLDGAD N AVEN PRP RLG R S R T GA GP PP V A SCTR PP TPPE A C R DAGPFPP K rprcfpwrdpar 1552
Cdd:PHA03307 850 ----- S S ES S K S K P A A A GGRARGK N GRRR PRP PEP R A R P GA AA PP K A AAAA PP AGAP A P R PRPAPRV K ------------ 912
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1553 im D G SLSL G DRRH RG a A FR KP P I G TPIAGYAGPPH L D AYCP G E G V D EL TSFAQI P TL WR QP LA RS PEA M AEIA RVAST P S 1632
Cdd:PHA03307 913 -- L G PMPP G GPDP RG - G FR RV P P G DLHTPAPSAAA L A AYCP P E V V A EL VDHPLF P EP WR PA LA FD PEA L AEIA ARCGG P P 989
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1633 HV S R S P dtaaseg VLCRT A VVS LR A R T AWMR h Q QAS PEDV AL V I LY TAN PGEHLF C VPAP GSP PGGP RFD P N RGGLSFLL 1712
Cdd:PHA03307 990 PR S G S A ------- FGPLR A SGP LR R R A AWMR - Q IPD PEDV RV V V LY SPL PGEHLF G VPAP DAS PGGP AWS P E RGGLSFLL 1061
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1713 AAL A NRLCLP E S A AWAG R W RA APDVSAL T A A GV MF LS PQ DL G FAG VL E H L QRLCLKREK RL V VLDT LEDR D R P EN GP R l V 1792
Cdd:PHA03307 1062 AAL G NRLCLP D S H AWAG N W TG APDVSAL N A Q GV LL LS TR DL A FAG AV E Y L CLRLGSARR RL I VLDT VDPE D W P AD GP A - V 1140
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1793 EEAVR Y V RC T V S PR S QC S VRWP GHP DLA TT V I TS RD V L GP VVLREL E TH F R R EN P A A GDIS LC C G S NVRY K V A TRL DRVA 1872
Cdd:PHA03307 1141 SQYHV Y L RC A V L PR A QC A VRWP AAR DLA RA V L TS SR V F GP GLFARV E AA F A R LY P D A PPLR LC R G A NVRY T V R TRL GPRT 1220
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1873 T VP MTALS Y LA A SSALVA G R --------- QRPPG PDFL A GE S HSHRAA LK WGL Y APLRPVY VL E PKKN AI VS PD F L NRT V 1943
Cdd:PHA03307 1221 R VP LPPRE Y RQ A VLPALD G C kdmaaqaeg LGLGA PDFL E GE A HSHRAA NR WGL G APLRPVY LA E GRRA AI AG PD E L PAV V 1300
1130 1140 1150 1160
....*....|....*....|....*....|....*....|....*....
gi 10834942 1944 CDV CR SVV L P PDP H A Q P V V VHV peatc S LL A REM la H L R SSS V V W LEGD 1992
Cdd:PHA03307 1301 RAF CR AAL L E PDP E A P P L V LPP ----- S AA A EAA -- H A R APR V T W AKSE 1342
PHA03307 super family
cl33723 transcriptional regulator ICP4; Provisional
1-418
1.30e-11
transcriptional regulator ICP4; Provisional
PHA03307 :Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 70.20
E-value: 1.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1 ME N P PD F Y S L L E ML A DN G G F S P Q PPATPGD P yqdvclntpsvavpptpgrqpvpprsksparaapvagslagarapfgie 80
Cdd:PHA03307 1 SD N A PD L Y D L I E AA A EG G E F F P R PPATPGD A ------------------------------------------------- 31
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 81 gavsegsdtglrsaep P D GAHQ GS P G EV VS ST A DIVD V CGNET AAA AP R SCSWQKT vgdlvpagserg E P S P MDPRKS N D 160
Cdd:PHA03307 32 ---------------- A D DLLS GS Q G QL VS DS A ELAA V TVVAG AAA CD R FEPPTGP ------------ P P G P GTEAPA N E 83
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 161 P vrcvsdapckptgactplavcvetlpppsgvppppppep IVNFP W TF S P L T P GPF A QHH SPTPP T P PPLS PPPPTPPP L 240
Cdd:PHA03307 84 S --------------------------------------- RSTPT W SL S T L A P ASP A REG SPTPP G P SSPD PPPPTPPP A 124
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 241 SPPP PTP P P LS PPPPTPPPHT PPP HG SPP PTPLPSTSPP S TQT SS PS A S LPL D SP PASTPP P PT P LHDR P L S PD P P A L S A 320
Cdd:PHA03307 125 SPPP SPA P D LS EMLRPVGSPG PPP AA SPP AAGASPAAVA S DAA SS RQ A A LPL S SP EETARA P SS P PAEP P P S TP P A A A S P 204
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 321 SCQ R P S P P L S P SA PRL APAP L RS DRVP A RRK SS V S EGGGPRTR G A G FQYV C R L SAS A R I PS P P R EELELVARQ P G S HAML 400
Cdd:PHA03307 205 RPP R R S S P I S A SA SSP APAP G RS AADD A GAS SS D S SSSESSGC G W G PENE C P L PRP A P I TL P T R IWEASGWNG P S S RPGP 284
410 420
....*....|....*....|..
gi 10834942 401 WR ---- AGA R DGATE PSS GDDP 418
Cdd:PHA03307 285 AS ssss PRE R SPSPS PSS PGSG 306
PHA03307 super family
cl33723 transcriptional regulator ICP4; Provisional
408-581
4.58e-05
transcriptional regulator ICP4; Provisional
PHA03307 :Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 48.63
E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 408 GA T E P SSGDD P KVFLLALSDA R RCP S YWDRL A REAVLREIL P TPRG S PLRT S PGSIEL pre APLLDSDY R PFEWRC A KGR 487
Cdd:PHA03307 118 PP T P P PASPP P SPAPDLSEML R PVG S PGPPP A ASPPAAGAS P AAVA S DAAS S RQAALP --- LSSPEETA R APSSPP A EPP 194
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 488 P LPQEPVFPCP P NELGNDWA A CKMWLFSRCA R lvl S TL DD MSP S EDGE S VL ES Q GCGWGP Q NECPLP L PAPI V LPTRIWE 567
Cdd:PHA03307 195 P STPPAAASPR P PRRSSPIS A SASSPAPAPG R --- S AA DD AGA S SSDS S SS ES S GCGWGP E NECPLP R PAPI T LPTRIWE 271
170
....*....|....
gi 10834942 568 A VTRLPRPAPRT P T 581
Cdd:PHA03307 272 A SGWNGPSSRPG P A 285
Name
Accession
Description
Interval
E-value
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
873-1992
0e+00
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 918.79
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 873 WNGPS P RPG LV SS PTGTQ ER YRRVQ P G S GSD G SHTTA P P A VLKQALQQ E VGTPA T RA S HPLP R PPPA S YPSLGC RS R S S S 952
Cdd:PHA03307 275 WNGPS S RPG PA SS SSSPR ER SPSPS P S S PGS G PAPSS P R A SSSSSSSR E SSSSS T SS S SESS R GAAV S PGPSPS RS P S P S 354
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 953 SSSASSSS SS SSSA P SS S EQS S AAPS S RTSSRS ptr EAGAPQC A A R G R G R GRG GR RGR GR RA PSP ------ S SETA A PP P 1026
Cdd:PHA03307 355 RPPPPADP SS PRKR P RP S RAP S SPAA S AGRPTR --- RRARAAV A G R A R R R DAT GR FPA GR PR PSP ldagaa S GAFY A RY P 431
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1027 PDDLDQ E V W WQI P S PP A GR CWF G P LG GH R QA L RGI PEV EQ AA V R FLST PGP L PVYV E EMG NC AKQY E ALV SAMLNK D VK A 1106
Cdd:PHA03307 432 LLTPSG E P W PGS P P PP P GR VRY G G LG DS R PG L WDA PEV RE AA A R YEAS PGP V PVYV P EMG DS AKQY A ALV RLLYTP D RE A 511
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1107 NP ln W AHHG KL SPT D A AL NHIYVT KF R s SHSSP G AAV TG T V NKCI PHI AS AM KKR N L LWALPH I AA S V S M T RRY CKD QK E 1186
Cdd:PHA03307 512 MG -- W LQNP KL TGP D Q AL DQFCQK KF Q - APRGS G SFI TG S V ARPV PHI GD AM AAG N A LWALPH A AA A V A M S RRY DRA QK G 588
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1187 F MFR SLR K AYAPMA SAAS A EMRR psaspisnrapvtaqstaaglipvidvstihdrvrrgvaafnsaleeglld VPEYRL 1266
Cdd:PHA03307 589 F LLQ SLR R AYAPMA YPEN A ADTG --------------------------------------------------- AGAAAP 617
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1267 VAP A RPDIP A GD G F AS T RPL N EL V DAC A L E C EG V VA ALL R GPDG PG A vaemlss CEDGP FPRPA GH - EQW E K C R A L L G SW 1345
Cdd:PHA03307 618 APA A PRPDA A AA G G AS A RPL R EL A DAC V L A C RA V LE ALL E GPDG LS A ------- VPGLA FPRPA CP p RAL E A C P A R L E SW 690
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1346 LR D L L DLR S AVY A A YAN G -- SAPR GR Q ER TL A AN A AA L ITEAIG PL LSKD P A R PWRCPGSR DIT SV L LRECGSRG ----- 1418
Cdd:PHA03307 691 LR E L R DLR D AVY L A RLR G dl PVAG GR E ER VA A VR A VS L VARTVA PL VRYS P R R ARARASAW DIT DA L FSNPSLVP aklae 770
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1419 ----------------- E PVR SREKA RR LQ R VA R LLAD ADAAS SGT S EGR SR --------- S AE P CYD PG P A SS P E P V R a 1472
Cdd:PHA03307 771 alallepaepqrgagss P PVR AEAAF RR PG R LR R SGPA ADAAS RTA S KRK SR shtpdggse S SG P ARP PG A A AR P P P A R - 849
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1473 lcaqt S A ES R K R K S A P A AVLDGAD N AVEN PRP RLG R S R T GA GP PP V A SCTR PP TPPE A C R DAGPFPP K rprcfpwrdpar 1552
Cdd:PHA03307 850 ----- S S ES S K S K P A A A GGRARGK N GRRR PRP PEP R A R P GA AA PP K A AAAA PP AGAP A P R PRPAPRV K ------------ 912
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1553 im D G SLSL G DRRH RG a A FR KP P I G TPIAGYAGPPH L D AYCP G E G V D EL TSFAQI P TL WR QP LA RS PEA M AEIA RVAST P S 1632
Cdd:PHA03307 913 -- L G PMPP G GPDP RG - G FR RV P P G DLHTPAPSAAA L A AYCP P E V V A EL VDHPLF P EP WR PA LA FD PEA L AEIA ARCGG P P 989
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1633 HV S R S P dtaaseg VLCRT A VVS LR A R T AWMR h Q QAS PEDV AL V I LY TAN PGEHLF C VPAP GSP PGGP RFD P N RGGLSFLL 1712
Cdd:PHA03307 990 PR S G S A ------- FGPLR A SGP LR R R A AWMR - Q IPD PEDV RV V V LY SPL PGEHLF G VPAP DAS PGGP AWS P E RGGLSFLL 1061
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1713 AAL A NRLCLP E S A AWAG R W RA APDVSAL T A A GV MF LS PQ DL G FAG VL E H L QRLCLKREK RL V VLDT LEDR D R P EN GP R l V 1792
Cdd:PHA03307 1062 AAL G NRLCLP D S H AWAG N W TG APDVSAL N A Q GV LL LS TR DL A FAG AV E Y L CLRLGSARR RL I VLDT VDPE D W P AD GP A - V 1140
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1793 EEAVR Y V RC T V S PR S QC S VRWP GHP DLA TT V I TS RD V L GP VVLREL E TH F R R EN P A A GDIS LC C G S NVRY K V A TRL DRVA 1872
Cdd:PHA03307 1141 SQYHV Y L RC A V L PR A QC A VRWP AAR DLA RA V L TS SR V F GP GLFARV E AA F A R LY P D A PPLR LC R G A NVRY T V R TRL GPRT 1220
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1873 T VP MTALS Y LA A SSALVA G R --------- QRPPG PDFL A GE S HSHRAA LK WGL Y APLRPVY VL E PKKN AI VS PD F L NRT V 1943
Cdd:PHA03307 1221 R VP LPPRE Y RQ A VLPALD G C kdmaaqaeg LGLGA PDFL E GE A HSHRAA NR WGL G APLRPVY LA E GRRA AI AG PD E L PAV V 1300
1130 1140 1150 1160
....*....|....*....|....*....|....*....|....*....
gi 10834942 1944 CDV CR SVV L P PDP H A Q P V V VHV peatc S LL A REM la H L R SSS V V W LEGD 1992
Cdd:PHA03307 1301 RAF CR AAL L E PDP E A P P L V LPP ----- S AA A EAA -- H A R APR V T W AKSE 1342
Herpes_ICP4_C
pfam03585 Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 ...
1568-1993
2.14e-113
Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the C-terminal region that probably acts as an enhancer for the N-terminal region.
Pssm-ID: 281570
Cd Length: 444
Bit Score: 368.55
E-value: 2.14e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1568 AA FR KP P I GT PIAGYAGPPH L D AYCP GEGVD EL TS F AQI P TL WR QP L ARS PEA M A E I - ARVA ST ----- PSHVSRSPDT A 1641
Cdd:pfam03585 1 GG FR RF P V GT VHTQTPPQSA L N AYCP PGAFA EL VD F PLF P EP WR PA L RFD PEA L A D I a ARVA NA lpggg DYNSNEIITS A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1642 AS EGVLCR TA VVS LR A RTAWMR h Q QAS PEDV AL V I LY TAN PGE H LFCVPAP GS PP ggp RFDPN RGGLSFLLAAL A NRLCL 1721
Cdd:pfam03585 81 AS RAFGPP TA TSK LR R RTAWMR - Q IPD PEDV RI V V LY SPL PGE D LFCVPAP DT PP --- KWSNK RGGLSFLLAAL S NRLCL 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1722 P ESA AWAG R W RA APDVSALTA A GV MF LS PQ DL G FAG VL E H L Q R L C L KR EK RL V V L DT L EDR DR P EN GP RLV EE AV r Y VR C 1801
Cdd:pfam03585 157 P KTS AWAG N W TG APDVSALTA M GV LL LS TR DL A FAG AV E Y L G R Q C M KR KR RL I V M DT V EDR YW P PD GP AIS EE HT - Y MK C 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1802 TV SPRSQC S VRWPG HP DL AT TVI T SR D V L GP VVLRE LE THFRREN P AAGDIS LC C G S NVRY K V A TRL DR V AT VP MTALS Y 1881
Cdd:pfam03585 236 II SPRSQC C VRWPG LL DL GR TVI A SR R V F GP LTFAR LE QAYAELY P EDSPLN LC R G G NVRY T V E TRL GP V TC VP TSPRE Y 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1882 L AA SSALVA G RQR --------- PPG PDFL AG E S HSHRAA LK WGL Y APLRPVYV L E PKK NAI VS P D FL NR - T VCDV CRS VV 1951
Cdd:pfam03585 316 R AA VLPVFD G CKD larqsrglg LGA PDFL CE E A HSHRAA RR WGL G APLRPVYV I E GRM NAI AG P S FL HV p T ARNF CRS AL 395
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 10834942 1952 L P PDP H A Q P V V V H V PE A TCS L LA RE M L A HLRSS -- SVV W LE G D G 1993
Cdd:pfam03585 396 L E PDP E A R P L V L H I PE G TCS A LA ED M V A SALPP cp RIT W GQ G F G 439
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
1-418
1.30e-11
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 70.20
E-value: 1.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1 ME N P PD F Y S L L E ML A DN G G F S P Q PPATPGD P yqdvclntpsvavpptpgrqpvpprsksparaapvagslagarapfgie 80
Cdd:PHA03307 1 SD N A PD L Y D L I E AA A EG G E F F P R PPATPGD A ------------------------------------------------- 31
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 81 gavsegsdtglrsaep P D GAHQ GS P G EV VS ST A DIVD V CGNET AAA AP R SCSWQKT vgdlvpagserg E P S P MDPRKS N D 160
Cdd:PHA03307 32 ---------------- A D DLLS GS Q G QL VS DS A ELAA V TVVAG AAA CD R FEPPTGP ------------ P P G P GTEAPA N E 83
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 161 P vrcvsdapckptgactplavcvetlpppsgvppppppep IVNFP W TF S P L T P GPF A QHH SPTPP T P PPLS PPPPTPPP L 240
Cdd:PHA03307 84 S --------------------------------------- RSTPT W SL S T L A P ASP A REG SPTPP G P SSPD PPPPTPPP A 124
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 241 SPPP PTP P P LS PPPPTPPPHT PPP HG SPP PTPLPSTSPP S TQT SS PS A S LPL D SP PASTPP P PT P LHDR P L S PD P P A L S A 320
Cdd:PHA03307 125 SPPP SPA P D LS EMLRPVGSPG PPP AA SPP AAGASPAAVA S DAA SS RQ A A LPL S SP EETARA P SS P PAEP P P S TP P A A A S P 204
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 321 SCQ R P S P P L S P SA PRL APAP L RS DRVP A RRK SS V S EGGGPRTR G A G FQYV C R L SAS A R I PS P P R EELELVARQ P G S HAML 400
Cdd:PHA03307 205 RPP R R S S P I S A SA SSP APAP G RS AADD A GAS SS D S SSSESSGC G W G PENE C P L PRP A P I TL P T R IWEASGWNG P S S RPGP 284
410 420
....*....|....*....|..
gi 10834942 401 WR ---- AGA R DGATE PSS GDDP 418
Cdd:PHA03307 285 AS ssss PRE R SPSPS PSS PGSG 306
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
408-581
4.58e-05
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 48.63
E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 408 GA T E P SSGDD P KVFLLALSDA R RCP S YWDRL A REAVLREIL P TPRG S PLRT S PGSIEL pre APLLDSDY R PFEWRC A KGR 487
Cdd:PHA03307 118 PP T P P PASPP P SPAPDLSEML R PVG S PGPPP A ASPPAAGAS P AAVA S DAAS S RQAALP --- LSSPEETA R APSSPP A EPP 194
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 488 P LPQEPVFPCP P NELGNDWA A CKMWLFSRCA R lvl S TL DD MSP S EDGE S VL ES Q GCGWGP Q NECPLP L PAPI V LPTRIWE 567
Cdd:PHA03307 195 P STPPAAASPR P PRRSSPIS A SASSPAPAPG R --- S AA DD AGA S SSDS S SS ES S GCGWGP E NECPLP R PAPI T LPTRIWE 271
170
....*....|....
gi 10834942 568 A VTRLPRPAPRT P T 581
Cdd:PHA03307 272 A SGWNGPSSRPG P A 285
Name
Accession
Description
Interval
E-value
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
873-1992
0e+00
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 918.79
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 873 WNGPS P RPG LV SS PTGTQ ER YRRVQ P G S GSD G SHTTA P P A VLKQALQQ E VGTPA T RA S HPLP R PPPA S YPSLGC RS R S S S 952
Cdd:PHA03307 275 WNGPS S RPG PA SS SSSPR ER SPSPS P S S PGS G PAPSS P R A SSSSSSSR E SSSSS T SS S SESS R GAAV S PGPSPS RS P S P S 354
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 953 SSSASSSS SS SSSA P SS S EQS S AAPS S RTSSRS ptr EAGAPQC A A R G R G R GRG GR RGR GR RA PSP ------ S SETA A PP P 1026
Cdd:PHA03307 355 RPPPPADP SS PRKR P RP S RAP S SPAA S AGRPTR --- RRARAAV A G R A R R R DAT GR FPA GR PR PSP ldagaa S GAFY A RY P 431
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1027 PDDLDQ E V W WQI P S PP A GR CWF G P LG GH R QA L RGI PEV EQ AA V R FLST PGP L PVYV E EMG NC AKQY E ALV SAMLNK D VK A 1106
Cdd:PHA03307 432 LLTPSG E P W PGS P P PP P GR VRY G G LG DS R PG L WDA PEV RE AA A R YEAS PGP V PVYV P EMG DS AKQY A ALV RLLYTP D RE A 511
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1107 NP ln W AHHG KL SPT D A AL NHIYVT KF R s SHSSP G AAV TG T V NKCI PHI AS AM KKR N L LWALPH I AA S V S M T RRY CKD QK E 1186
Cdd:PHA03307 512 MG -- W LQNP KL TGP D Q AL DQFCQK KF Q - APRGS G SFI TG S V ARPV PHI GD AM AAG N A LWALPH A AA A V A M S RRY DRA QK G 588
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1187 F MFR SLR K AYAPMA SAAS A EMRR psaspisnrapvtaqstaaglipvidvstihdrvrrgvaafnsaleeglld VPEYRL 1266
Cdd:PHA03307 589 F LLQ SLR R AYAPMA YPEN A ADTG --------------------------------------------------- AGAAAP 617
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1267 VAP A RPDIP A GD G F AS T RPL N EL V DAC A L E C EG V VA ALL R GPDG PG A vaemlss CEDGP FPRPA GH - EQW E K C R A L L G SW 1345
Cdd:PHA03307 618 APA A PRPDA A AA G G AS A RPL R EL A DAC V L A C RA V LE ALL E GPDG LS A ------- VPGLA FPRPA CP p RAL E A C P A R L E SW 690
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1346 LR D L L DLR S AVY A A YAN G -- SAPR GR Q ER TL A AN A AA L ITEAIG PL LSKD P A R PWRCPGSR DIT SV L LRECGSRG ----- 1418
Cdd:PHA03307 691 LR E L R DLR D AVY L A RLR G dl PVAG GR E ER VA A VR A VS L VARTVA PL VRYS P R R ARARASAW DIT DA L FSNPSLVP aklae 770
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1419 ----------------- E PVR SREKA RR LQ R VA R LLAD ADAAS SGT S EGR SR --------- S AE P CYD PG P A SS P E P V R a 1472
Cdd:PHA03307 771 alallepaepqrgagss P PVR AEAAF RR PG R LR R SGPA ADAAS RTA S KRK SR shtpdggse S SG P ARP PG A A AR P P P A R - 849
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1473 lcaqt S A ES R K R K S A P A AVLDGAD N AVEN PRP RLG R S R T GA GP PP V A SCTR PP TPPE A C R DAGPFPP K rprcfpwrdpar 1552
Cdd:PHA03307 850 ----- S S ES S K S K P A A A GGRARGK N GRRR PRP PEP R A R P GA AA PP K A AAAA PP AGAP A P R PRPAPRV K ------------ 912
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1553 im D G SLSL G DRRH RG a A FR KP P I G TPIAGYAGPPH L D AYCP G E G V D EL TSFAQI P TL WR QP LA RS PEA M AEIA RVAST P S 1632
Cdd:PHA03307 913 -- L G PMPP G GPDP RG - G FR RV P P G DLHTPAPSAAA L A AYCP P E V V A EL VDHPLF P EP WR PA LA FD PEA L AEIA ARCGG P P 989
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1633 HV S R S P dtaaseg VLCRT A VVS LR A R T AWMR h Q QAS PEDV AL V I LY TAN PGEHLF C VPAP GSP PGGP RFD P N RGGLSFLL 1712
Cdd:PHA03307 990 PR S G S A ------- FGPLR A SGP LR R R A AWMR - Q IPD PEDV RV V V LY SPL PGEHLF G VPAP DAS PGGP AWS P E RGGLSFLL 1061
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1713 AAL A NRLCLP E S A AWAG R W RA APDVSAL T A A GV MF LS PQ DL G FAG VL E H L QRLCLKREK RL V VLDT LEDR D R P EN GP R l V 1792
Cdd:PHA03307 1062 AAL G NRLCLP D S H AWAG N W TG APDVSAL N A Q GV LL LS TR DL A FAG AV E Y L CLRLGSARR RL I VLDT VDPE D W P AD GP A - V 1140
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1793 EEAVR Y V RC T V S PR S QC S VRWP GHP DLA TT V I TS RD V L GP VVLREL E TH F R R EN P A A GDIS LC C G S NVRY K V A TRL DRVA 1872
Cdd:PHA03307 1141 SQYHV Y L RC A V L PR A QC A VRWP AAR DLA RA V L TS SR V F GP GLFARV E AA F A R LY P D A PPLR LC R G A NVRY T V R TRL GPRT 1220
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1873 T VP MTALS Y LA A SSALVA G R --------- QRPPG PDFL A GE S HSHRAA LK WGL Y APLRPVY VL E PKKN AI VS PD F L NRT V 1943
Cdd:PHA03307 1221 R VP LPPRE Y RQ A VLPALD G C kdmaaqaeg LGLGA PDFL E GE A HSHRAA NR WGL G APLRPVY LA E GRRA AI AG PD E L PAV V 1300
1130 1140 1150 1160
....*....|....*....|....*....|....*....|....*....
gi 10834942 1944 CDV CR SVV L P PDP H A Q P V V VHV peatc S LL A REM la H L R SSS V V W LEGD 1992
Cdd:PHA03307 1301 RAF CR AAL L E PDP E A P P L V LPP ----- S AA A EAA -- H A R APR V T W AKSE 1342
Herpes_ICP4_C
pfam03585 Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 ...
1568-1993
2.14e-113
Herpesvirus ICP4-like protein C-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the C-terminal region that probably acts as an enhancer for the N-terminal region.
Pssm-ID: 281570
Cd Length: 444
Bit Score: 368.55
E-value: 2.14e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1568 AA FR KP P I GT PIAGYAGPPH L D AYCP GEGVD EL TS F AQI P TL WR QP L ARS PEA M A E I - ARVA ST ----- PSHVSRSPDT A 1641
Cdd:pfam03585 1 GG FR RF P V GT VHTQTPPQSA L N AYCP PGAFA EL VD F PLF P EP WR PA L RFD PEA L A D I a ARVA NA lpggg DYNSNEIITS A 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1642 AS EGVLCR TA VVS LR A RTAWMR h Q QAS PEDV AL V I LY TAN PGE H LFCVPAP GS PP ggp RFDPN RGGLSFLLAAL A NRLCL 1721
Cdd:pfam03585 81 AS RAFGPP TA TSK LR R RTAWMR - Q IPD PEDV RI V V LY SPL PGE D LFCVPAP DT PP --- KWSNK RGGLSFLLAAL S NRLCL 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1722 P ESA AWAG R W RA APDVSALTA A GV MF LS PQ DL G FAG VL E H L Q R L C L KR EK RL V V L DT L EDR DR P EN GP RLV EE AV r Y VR C 1801
Cdd:pfam03585 157 P KTS AWAG N W TG APDVSALTA M GV LL LS TR DL A FAG AV E Y L G R Q C M KR KR RL I V M DT V EDR YW P PD GP AIS EE HT - Y MK C 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1802 TV SPRSQC S VRWPG HP DL AT TVI T SR D V L GP VVLRE LE THFRREN P AAGDIS LC C G S NVRY K V A TRL DR V AT VP MTALS Y 1881
Cdd:pfam03585 236 II SPRSQC C VRWPG LL DL GR TVI A SR R V F GP LTFAR LE QAYAELY P EDSPLN LC R G G NVRY T V E TRL GP V TC VP TSPRE Y 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1882 L AA SSALVA G RQR --------- PPG PDFL AG E S HSHRAA LK WGL Y APLRPVYV L E PKK NAI VS P D FL NR - T VCDV CRS VV 1951
Cdd:pfam03585 316 R AA VLPVFD G CKD larqsrglg LGA PDFL CE E A HSHRAA RR WGL G APLRPVYV I E GRM NAI AG P S FL HV p T ARNF CRS AL 395
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 10834942 1952 L P PDP H A Q P V V V H V PE A TCS L LA RE M L A HLRSS -- SVV W LE G D G 1993
Cdd:pfam03585 396 L E PDP E A R P L V L H I PE G TCS A LA ED M V A SALPP cp RIT W GQ G F G 439
Herpes_ICP4_N
pfam03584 Herpesvirus ICP4-like protein N-terminal region; The immediate-early protein ICP4 ...
1041-1200
1.89e-61
Herpesvirus ICP4-like protein N-terminal region; The immediate-early protein ICP4 (infected-cell polypeptide 4) is required for efficient transcription of early and late viral genes and is thus essential for productive infection. ICP4 is a large phosphoprotein that binds DNA in a sequence specific manner as a homodimer. ICP4 represses transcription from LAT, ICP4 and ORF-P that have high-affinity a ICP4 binding site that spans the transcription initiation site. ICP4 proteins have two highly conserved regions, this family contains the N-terminal region that contains sites for DNA binding and homodimerization.
Pssm-ID: 367571 [Multi-domain]
Cd Length: 163
Bit Score: 207.76
E-value: 1.89e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1041 PP A GR CWF G P LG GH R QA L R G I PEV EQ A AV RF LSTPG P L PVYV E E M G NC A K QY E ALV SAMLNK D V ka N PL N W AHHGK L S P T 1120
Cdd:pfam03584 2 PP P GR VLY G G LG DS R PG L W G A PEV RE A RA RF EASGA P A PVYV P E L G DA A Q QY A ALV NLLYTP D A -- E PL G W LQNPR L N P G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1121 D A ALN H I Y v T K FRSSHSSP G A AVTG T V NKCI PHI AS AM KKRNL LWALPH I AA S V S M T RRY CKD QK E F MFR SLR K AYAP M A 1200
Cdd:pfam03584 80 D V ALN Q I C - Q K ISGAARNS G S AVTG S V ARAV PHI GY AM AAGRA LWALPH A AA A V A M S RRY DRA QK T F LLT SLR R AYAP L A 158
PHA03308
PHA03308 transcriptional regulator ICP4; Provisional
1038-1221
1.50e-17
transcriptional regulator ICP4; Provisional
Pssm-ID: 165563 [Multi-domain]
Cd Length: 1463
Bit Score: 89.87
E-value: 1.50e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1038 IPSPP A - G RCWF G pl G G H RQ A L RGI P E V EQ AA VR F LST P GPLP VY V EE M G NCAK Q Y E A LV SAML nkdvk AN PL NWAHH G - 1115
Cdd:PHA03308 355 IPSPP S r G QVYH G -- S G Y RQ S L VDD P Q V RE AA AE F HAN P KSAS VY L EE Y G MPVE Q L E R LV EEFM ----- VH PL SRVSY G y 427
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1116 --- KLSP T D AA L NHI yv TKF R SSH SS P G AAVTGT V NK C I PH I A S AM KKRNLLW ALPH IAAS V SMT RRY CKD QK EFMFRS L 1192
Cdd:PHA03308 428 ggp KLSP R D KR L CEL -- CAL R GPG SS E G GLSRSA V PT C L PH V A H AM RDGRVSL ALPH LTEL V RVC RRY DHP QK TYLLAA L 505
170 180
....*....|....*....|....*....
gi 10834942 1193 R K A YA P MASAAS A E mr R P S A SPI S NRA PV 1221
Cdd:PHA03308 506 R R A FV P FVFPGA A V -- D P T A ASA S GDH PV 532
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
1-418
1.30e-11
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 70.20
E-value: 1.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1 ME N P PD F Y S L L E ML A DN G G F S P Q PPATPGD P yqdvclntpsvavpptpgrqpvpprsksparaapvagslagarapfgie 80
Cdd:PHA03307 1 SD N A PD L Y D L I E AA A EG G E F F P R PPATPGD A ------------------------------------------------- 31
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 81 gavsegsdtglrsaep P D GAHQ GS P G EV VS ST A DIVD V CGNET AAA AP R SCSWQKT vgdlvpagserg E P S P MDPRKS N D 160
Cdd:PHA03307 32 ---------------- A D DLLS GS Q G QL VS DS A ELAA V TVVAG AAA CD R FEPPTGP ------------ P P G P GTEAPA N E 83
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 161 P vrcvsdapckptgactplavcvetlpppsgvppppppep IVNFP W TF S P L T P GPF A QHH SPTPP T P PPLS PPPPTPPP L 240
Cdd:PHA03307 84 S --------------------------------------- RSTPT W SL S T L A P ASP A REG SPTPP G P SSPD PPPPTPPP A 124
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 241 SPPP PTP P P LS PPPPTPPPHT PPP HG SPP PTPLPSTSPP S TQT SS PS A S LPL D SP PASTPP P PT P LHDR P L S PD P P A L S A 320
Cdd:PHA03307 125 SPPP SPA P D LS EMLRPVGSPG PPP AA SPP AAGASPAAVA S DAA SS RQ A A LPL S SP EETARA P SS P PAEP P P S TP P A A A S P 204
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 321 SCQ R P S P P L S P SA PRL APAP L RS DRVP A RRK SS V S EGGGPRTR G A G FQYV C R L SAS A R I PS P P R EELELVARQ P G S HAML 400
Cdd:PHA03307 205 RPP R R S S P I S A SA SSP APAP G RS AADD A GAS SS D S SSSESSGC G W G PENE C P L PRP A P I TL P T R IWEASGWNG P S S RPGP 284
410 420
....*....|....*....|..
gi 10834942 401 WR ---- AGA R DGATE PSS GDDP 418
Cdd:PHA03307 285 AS ssss PRE R SPSPS PSS PGSG 306
PHA03309
PHA03309 transcriptional regulator ICP4; Provisional
1038-1256
2.14e-08
transcriptional regulator ICP4; Provisional
Pssm-ID: 165564 [Multi-domain]
Cd Length: 2033
Bit Score: 59.87
E-value: 2.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1038 I P S PPA GRCWFGPLG G H R QALRGI P E V EQ AA VR F LSTPGPLP VYVEE M G NCAK Q Y E A LV SAML nkdvk AN PL NWAH H G -- 1115
Cdd:PHA03309 629 L P K PPA ADYVYYGKT G Y R PSMAAH P D V RR AA EE F SASDAAAR VYVEE F G MAVE Q H E R LV AEFM ----- LQ PL SRVS H S yg 703
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 1116 -- K L SP T DAA L NH I YVTKFRSSHSSP G AAVT G ------------ TVNKCI PHI AS AM KKRNLLW ALPH IAASVSMT RRY C 1181
Cdd:PHA03309 704 gs R L NK T EKN L CK I CLPPDGGDDRDG G GKSR G grgggskdasrt AMATGV PHI VH AM RDGRAAL ALPH LMDVIRVC RRY D 783
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 10834942 1182 KD QK EFMFRS LR K A Y AP MAS aasaemrr P S ASP isnra PV T A QSTAAGLI P VIDVSTI hdr V R R G VA A F N SALE E 1256
Cdd:PHA03309 784 AS QK TYLLSC LR L A F AP LVF -------- P G ASP ----- PV G A DDSPWPTS P IRECAAA --- L R E G FR A L N DIRA E 842
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
408-581
4.58e-05
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 48.63
E-value: 4.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 408 GA T E P SSGDD P KVFLLALSDA R RCP S YWDRL A REAVLREIL P TPRG S PLRT S PGSIEL pre APLLDSDY R PFEWRC A KGR 487
Cdd:PHA03307 118 PP T P P PASPP P SPAPDLSEML R PVG S PGPPP A ASPPAAGAS P AAVA S DAAS S RQAALP --- LSSPEETA R APSSPP A EPP 194
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 10834942 488 P LPQEPVFPCP P NELGNDWA A CKMWLFSRCA R lvl S TL DD MSP S EDGE S VL ES Q GCGWGP Q NECPLP L PAPI V LPTRIWE 567
Cdd:PHA03307 195 P STPPAAASPR P PRRSSPIS A SASSPAPAPG R --- S AA DD AGA S SSDS S SS ES S GCGWGP E NECPLP R PAPI T LPTRIWE 271
170
....*....|....
gi 10834942 568 A VTRLPRPAPRT P T 581
Cdd:PHA03307 272 A SGWNGPSSRPG P A 285
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
