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Conserved domains on  [gi|117676405|ref|NP_083562|]
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coiled-coil domain-containing protein 30 isoform a [Mus musculus]

Protein Classification

coiled-coil domain-containing protein 30( domain architecture ID 12174440)

coiled-coil domain-containing protein 30 (CCDC30) is a DUF4686 domain-containing protein that may be a new cytoskeletal element functionally associated with the filament motor system of the cytoskeleton

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 170-547 1.56e-143

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


:

Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 422.55  E-value: 1.56e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  170 LTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSS 249
Cdd:pfam15742   1 VSSGEKLKYQQQEEVQQLRQNLQRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  250 LTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEI 329
Cdd:pfam15742  81 LTAEWKHCQQKIRELELEVLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEKKQLEERI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  330 KEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNS------QQQEALRKQLERERRKCEEYVKSN 403
Cdd:pfam15742 161 KEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSqqqlriQQQEAQLKQLENEKRKSDEHLKSN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  404 QELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEM 483
Cdd:pfam15742 241 QELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHKAKLRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEK 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117676405  484 EKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRL 547
Cdd:pfam15742 321 EKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIKNNKRTISSVQNRVNFLDEENKQLQENTLRL 384
 
Name Accession Description Interval E-value
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 170-547 1.56e-143

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 422.55  E-value: 1.56e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  170 LTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSS 249
Cdd:pfam15742   1 VSSGEKLKYQQQEEVQQLRQNLQRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  250 LTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEI 329
Cdd:pfam15742  81 LTAEWKHCQQKIRELELEVLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEKKQLEERI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  330 KEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNS------QQQEALRKQLERERRKCEEYVKSN 403
Cdd:pfam15742 161 KEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSqqqlriQQQEAQLKQLENEKRKSDEHLKSN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  404 QELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEM 483
Cdd:pfam15742 241 QELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHKAKLRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEK 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117676405  484 EKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRL 547
Cdd:pfam15742 321 EKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIKNNKRTISSVQNRVNFLDEENKQLQENTLRL 384
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 166-478 5.75e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 5.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   166 GEMYLTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNAR 245
Cdd:TIGR02169  658 GSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   246 LHSSLTAEWKHCQQKVKELELEglrqtqslksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDvcilRKKQL 325
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSE----------LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQA----ELSKL 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   326 EEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDkeeqQEAVNSQQQEALRKQLERERRKCEEYVKSNQE 405
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE----QIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117676405   406 LSEKLSNLQQEKealwqehgrflEQLGDHVRNYKDKHHCHKAKLQKVKDR---LTHELEIRNKRIKELEDETGKLQ 478
Cdd:TIGR02169  880 LESRLGDLKKER-----------DELEAQLRELERKIEELEAQIEKKRKRlseLKAKLEALEEELSEIEDPKGEDE 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 183-482 1.93e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 183 ELRELRQNLRRLQILCNS-----------AEKELRYER-GRSLDLKQHNSLLQEENiKIKIELKQAQEKLLDNARLHSSL 250
Cdd:COG1196  180 KLEATEENLERLEDILGElerqleplerqAEKAERYRElKEELKELEAELLLLKLR-ELEAELEELEAELEELEAELEEL 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 251 TAEWKHCQQKVKELELEGLRQTQSLKSQQG----LQEKLAREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLE 326
Cdd:COG1196  259 EAELAELEAELEELRLELEELELELEEAQAeeyeLLAELARLEQDIARLEERRRELEERLEELEE---------ELAELE 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 327 EEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQEL 406
Cdd:COG1196  330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEEL 405

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117676405 407 SEKLSNLQQEKEALWQEHGRFLEQLgDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIE 482
Cdd:COG1196  406 EEAEEALLERLERLEEELEELEEAL-AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
46 PHA02562
endonuclease subunit; Provisional
 353-481 8.12e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 8.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 353 LDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKE-------ALWQEHG 425
Cdd:PHA02562 186 LDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEdpsaalnKLNTAAA 265

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117676405 426 RF---LEQLGDHVRNYKDKHHC---------HKAKLQKVKDR---LTHELEIRNKRIKELE---DETGKLQQKI 481
Cdd:PHA02562 266 KIkskIEQFQKVIKMYEKGGVCptctqqiseGPDRITKIKDKlkeLQHSLEKLDTAIDELEeimDEFNEQSKKL 339
 
Name Accession Description Interval E-value
DUF4686 pfam15742
Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins ...
 170-547 1.56e-143

Domain of unknown function (DUF4686); This family of proteins is found in eukaryotes. Proteins in this family are typically between 498 and 775 amino acids in length. There is a conserved DLK sequence motif.


Pssm-ID: 464838 [Multi-domain]  Cd Length: 384  Bit Score: 422.55  E-value: 1.56e-143
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  170 LTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSS 249
Cdd:pfam15742   1 VSSGEKLKYQQQEEVQQLRQNLQRLQILCTSAEKELRYERGKNLDLKQHNSLLQEENIKIKAELKQAQQKLLDSTKMCSS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  250 LTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEI 329
Cdd:pfam15742  81 LTAEWKHCQQKIRELELEVLKQAQSIKSQNSLQEKLAQEKSRVADAEEKILELQQKLEHAHKVCLTDTCILEKKQLEERI 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  330 KEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNS------QQQEALRKQLERERRKCEEYVKSN 403
Cdd:pfam15742 161 KEASENEAKLKQQYQEEQQKRKLLDQNVNELQQQVRSLQDKEAQLEMTNSqqqlriQQQEAQLKQLENEKRKSDEHLKSN 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  404 QELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEM 483
Cdd:pfam15742 241 QELSEKLSSLQQEKEALQEELQQVLKQLDVHVRKYNEKHHHHKAKLRRAKDRLVHEVEQRDERIKQLENEIGILQQQSEK 320

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117676405  484 EKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRL 547
Cdd:pfam15742 321 EKAFQKQVTAQNEILLLEKRKLLEQLTEQEELIKNNKRTISSVQNRVNFLDEENKQLQENTLRL 384
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 166-478 5.75e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 5.75e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   166 GEMYLTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNAR 245
Cdd:TIGR02169  658 GSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   246 LHSSLTAEWKHCQQKVKELELEglrqtqslksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDvcilRKKQL 325
Cdd:TIGR02169  738 RLEELEEDLSSLEQEIENVKSE----------LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQA----ELSKL 803

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   326 EEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDkeeqQEAVNSQQQEALRKQLERERRKCEEYVKSNQE 405
Cdd:TIGR02169  804 EEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKE----QIKSIEKEIENLNGKKEELEEELEELEAALRD 879

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117676405   406 LSEKLSNLQQEKealwqehgrflEQLGDHVRNYKDKHHCHKAKLQKVKDR---LTHELEIRNKRIKELEDETGKLQ 478
Cdd:TIGR02169  880 LESRLGDLKKER-----------DELEAQLRELERKIEELEAQIEKKRKRlseLKAKLEALEEELSEIEDPKGEDE 944
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 183-482 1.93e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.93e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 183 ELRELRQNLRRLQILCNS-----------AEKELRYER-GRSLDLKQHNSLLQEENiKIKIELKQAQEKLLDNARLHSSL 250
Cdd:COG1196  180 KLEATEENLERLEDILGElerqleplerqAEKAERYRElKEELKELEAELLLLKLR-ELEAELEELEAELEELEAELEEL 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 251 TAEWKHCQQKVKELELEGLRQTQSLKSQQG----LQEKLAREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLE 326
Cdd:COG1196  259 EAELAELEAELEELRLELEELELELEEAQAeeyeLLAELARLEQDIARLEERRRELEERLEELEE---------ELAELE 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 327 EEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQEL 406
Cdd:COG1196  330 EELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE----EELEELAEELLEALRAAAELAAQLEEL 405

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117676405 407 SEKLSNLQQEKEALWQEHGRFLEQLgDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIE 482
Cdd:COG1196  406 EEAEEALLERLERLEEELEELEEAL-AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 115-395 2.16e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 2.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 115 EIEKLKDNLMKLKesgttdLQRAREHNQRLDEEILALRNRVRSLDSEKKVLgEMYLTSGEKTSCQHQGELRELRQNLRRL 194
Cdd:COG1196  221 ELKELEAELLLLK------LRELEAELEELEAELEELEAELEELEAELAEL-EAELEELRLELEELELELEEAQAEEYEL 293

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 195 QILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQS 274
Cdd:COG1196  294 LAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 275 LKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRiLLD 354
Cdd:COG1196  374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE-EEA 452

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 117676405 355 QDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRK 395
Cdd:COG1196  453 ELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 183-482 2.62e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.46  E-value: 2.62e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   183 ELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVK 262
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   263 ELELEglrqtqslksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLEEEIKEAKSIEARLQQQ 342
Cdd:TIGR02168  758 ELEAE----------IEELEERLEEAEEELAEAEAEIEELEAQIEQLKE---------ELKALREALDELRAELTLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   343 CQEEQQRRILLDQDINELQTQVRALqdkeEQQEAVNSQQQEALRKQLERERRKCEEyvkSNQELsEKLSNLQQEKEALWQ 422
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDL----EEQIEELSEDIESLAAEIEELEELIEE---LESEL-EALLNERASLEEALA 890

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   423 EHGRFLEQLGDHVRNYKDKhhchkaklqkvKDRLTHELEIRNKRIKELEDETGKLQQKIE 482
Cdd:TIGR02168  891 LLRSELEELSEELRELESK-----------RSELRRELEELREKLAQLELRLEGLEVRID 939
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 258-516 2.97e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.79  E-value: 2.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 258 QQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVclSDVCILRKKQLEEEIKEAKSIEA 337
Cdd:COG1196  221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLE--LEELELELEEAQAEEYELLAELA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 338 RLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEK 417
Cdd:COG1196  299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 418 EALWQEHGRFLEQLGDHVRNYKDKHHchkakLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDI 497
Cdd:COG1196  379 EELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                        250
                 ....*....|....*....
gi 117676405 498 LLLEKRKLLEQVTDQEELI 516
Cdd:COG1196  454 LEEEEEALLELLAELLEEA 472
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 71-391 6.68e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 6.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  71 LLRDVECIAQKLEASLEEIHRGAREPREEREQRTLGDA-LENARLEIEKLKDnlmklkesgttDLQRAREHNQRLDEEIL 149
Cdd:COG1196  230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAeLEELRLELEELEL-----------ELEEAQAEEYELLAELA 298

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 150 ALRNRVRSLDSEKKvlgemyltsgektscQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKI 229
Cdd:COG1196  299 RLEQDIARLEERRR---------------ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEA 363

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 230 KIELKQAQEKLLDNARlhsSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHG 309
Cdd:COG1196  364 EEALLEAEAELAEAEE---ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 310 RQVCLSDvcILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQL 389
Cdd:COG1196  441 EEALEEA--AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAG 518


                 ..
gi 117676405 390 ER 391
Cdd:COG1196  519 LR 520
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 283-562 3.56e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 3.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   283 EKLAREKSKAaeaqEKILDLQQKLDHGRQVCLSdvciLRKKQLEEEIKEaksIEARLQQQCQEEQQRRILLDQDINELQT 362
Cdd:TIGR02169  201 ERLRREREKA----ERYQALLKEKREYEGYELL----KEKEALERQKEA---IERQLASLEEELEKLTEEISELEKRLEE 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   363 QVRALQDKEEQQEAVNSQQQEALRKQL-------ERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQLGDhV 435
Cdd:TIGR02169  270 IEQLLEELNKKIKDLGEEEQLRVKEKIgeleaeiASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEE-E 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   436 RNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDILLLEKRKLLEQVTDQEEL 515
Cdd:TIGR02169  349 RKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAA 428

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 117676405   516 ICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQ 562
Cdd:TIGR02169  429 IAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 230-482 9.43e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.90  E-value: 9.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   230 KIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELE--LEGLRQTQSLKSQQ--GLQEKLAREKSKAAEAQEKILDLQQK 305
Cdd:TIGR02168  676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEeeLEQLRKELEELSRQisALRKDLARLEAEVEQLEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   306 LDHGRQVCLSDVciLRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEAL 385
Cdd:TIGR02168  756 LTELEAEIEELE--ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR----ERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   386 RKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQLgDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNK 465
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL-EALLNERASLEEALALLRSELEELSEELRELES 908

                          250
                   ....*....|....*..
gi 117676405   466 RIKELEDETGKLQQKIE 482
Cdd:TIGR02168  909 KRSELRRELEELREKLA 925
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
236-440 1.15e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 1.15e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  236 AQEKLLDNARLHSSLTAEWKHCQQKVKELELEgLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHgrqvCLS 315
Cdd:COG4913   608 NRAKLAALEAELAELEEELAEAEERLEALEAE-LDALQERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDA 682

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  316 DVCILRkkQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDkeeQQEAVNSQQQEALRKQLErERRK 395
Cdd:COG4913   683 SSDDLA--ALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD---RLEAAEDLARLELRALLE-ERFA 756

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 117676405  396 CEEYVKSNQELSEKLSN-LQQEKEALWQEHGRFLEQLGDHVRNYKD 440
Cdd:COG4913   757 AALGDAVERELRENLEErIDALRARLNRAEEELERAMRAFNREWPA 802
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 181-432 1.46e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.51  E-value: 1.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   181 QGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQK 260
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEER 769

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   261 VKELELEGLRQTQSLKSQQGLQEKLARE----KSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLEEEIKEAKSIE 336
Cdd:TIGR02168  770 LEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAANLRE---------RLESLERRIAATERRL 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   337 ARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERErrkcEEYVKSNQELSEKLSNLQQE 416
Cdd:TIGR02168  841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRE 916

                          250
                   ....*....|....*.
gi 117676405   417 KEALWQEHGRFLEQLG 432
Cdd:TIGR02168  917 LEELREKLAQLELRLE 932
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 115-420 2.05e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 47.76  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   115 EIEKLKDNLMKLKESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKVLGEMYLTSGEKTSCQHQGELRELRQNLRRL 194
Cdd:TIGR02169  227 ELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   195 QilCNSAEKELRYErgrslDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEglrqtqs 274
Cdd:TIGR02169  307 E--RSIAEKERELE-----DAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE------- 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   275 lksQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVclSDVCILRKKQLEEEIKEAKSIEARLQqqcqeeqqrrilld 354
Cdd:TIGR02169  373 ---LEEVDKEFAETRDELKDYREKLEKLKREINELKRE--LDRLQEELQRLSEELADLNAAIAGIE-------------- 433

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117676405   355 QDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEAL 420
Cdd:TIGR02169  434 AKINELEEEKEDKALEIKKQE----WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 259-582 2.16e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   259 QKVKEL--ELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLdhgrqvclsdvcilrkKQLEEEIKEAKSIE 336
Cdd:TIGR02168  213 ERYKELkaELRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL----------------QELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   337 ARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQE 416
Cdd:TIGR02168  277 SELEEEIEELQKELYALANEISRLEQQKQILRERLANLE----RQLEELEAQLEELESKLDELAEELAELEEKLEELKEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   417 KEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDrLTHELEIRNKRIKELEDETGKLQQKIEMEKvfQGQIMAQND 496
Cdd:TIGR02168  353 LESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ-LELQIASLNNEIERLEARLERLEDRRERLQ--QEIEELLKK 429

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   497 ILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRREEETVITDNAA 576
Cdd:TIGR02168  430 LEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509


                   ....*.
gi 117676405   577 FEILKK 582
Cdd:TIGR02168  510 ALLKNQ 515
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 109-431 2.16e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 2.16e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   109 LENARLEIEKLKDNLMKLKESGttdlQRAREHNQRLDE-EILALRNRVRSLDSEKKVLgemyltsgEKTSCQHQGELREL 187
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKA----ERYKELKAELRElELALLVLRLEELREELEEL--------QEELKEAEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   188 RQNLRRLQILCNSAEKElRYERGRSLDLKQHNSLlqeeNIKIKIELKQAQEKLLDNARlhssltaewkhcQQKVKELELE 267
Cdd:TIGR02168  259 TAELQELEEKLEELRLE-VSELEEEIEELQKELY----ALANEISRLEQQKQILRERL------------ANLERQLEEL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   268 GLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQvcLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQ 347
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEA--ELEELESRLEELEEQLETLRSKVAQLELQIASLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   348 QRRILLDQDINELQTQV-RALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGR 426
Cdd:TIGR02168  400 NEIERLEARLERLEDRReRLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479


                   ....*
gi 117676405   427 FLEQL 431
Cdd:TIGR02168  480 AEREL 484
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 127-457 1.44e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   127 KESGTTDLQRAREHNQRLDEEILALRNRVRSLDSEKKVLGEMYLTSGEKTSCQ---HQGELRELRQNLRRLQILCNSAEK 203
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEgyeLLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   204 EL-RYERGRSLDLKQHNSLLQE-ENIKIKIELKQAQEKLLDNARLHSsLTAEWKHCQQKVKELELEglrQTQSLKSQQGL 281
Cdd:TIGR02169  252 ELeKLTEEISELEKRLEEIEQLlEELNKKIKDLGEEEQLRVKEKIGE-LEAEIASLERSIAEKERE---LEDAEERLAKL 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   282 QEKLAREKSKAAEAQEKILDLQQKLDHgrqvcLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQ---DIN 358
Cdd:TIGR02169  328 EAEIDKLLAEIEELEREIEEERKRRDK-----LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKlkrEIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   359 ELQTQVRALQDKEEQQeavnSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEkealwqehgrfLEQLGDHVRNY 438
Cdd:TIGR02169  403 ELKRELDRLQEELQRL----SEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK-----------LEQLAADLSKY 467

                          330
                   ....*....|....*....
gi 117676405   439 KDKHHCHKAKLQKVKDRLT 457
Cdd:TIGR02169  468 EQELYDLKEEYDRVEKELS 486
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
211-431 1.48e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 1.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 211 RSLDLKQHNSLLQEENIKIKIELKQAQEKLLDnarlhssltaewkhCQQKVKELELEGlRQTQSLKSQQGLQEKLAREKS 290
Cdd:COG3206  169 RREEARKALEFLEEQLPELRKELEEAEAALEE--------------FRQKNGLVDLSE-EAKLLLQQLSELESQLAEARA 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 291 KAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDK 370
Cdd:COG3206  234 ELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQR 313

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 117676405 371 EEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQL 431
Cdd:COG3206  314 ILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRL 374
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 328-567 3.69e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 43.89  E-value: 3.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   328 EIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEavnsQQQEALRKQLERERRKCEEYVKSNQELS 407
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELS----RQISALRKDLARLEAEVEQLEERIAQLS 753

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   408 EKLSNLQQEKEALWQEhgrfLEQLGDHVRNYKDKHHCHKAKLQKVKDRL---THELEIRNKRIKELEDETGKLQQKIEME 484
Cdd:TIGR02168  754 KELTELEAEIEELEER----LEEAEEELAEAEAEIEELEAQIEQLKEELkalREALDELRAELTLLNEEAANLRERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   485 KVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIR 564
Cdd:TIGR02168  830 ERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESK 909


                   ...
gi 117676405   565 REE 567
Cdd:TIGR02168  910 RSE 912
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
232-415 3.81e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.75  E-value: 3.81e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  232 ELKQAQEKLLDNARLHSSLTAEWKHcQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDL-QQKLDHGR 310
Cdd:COG4913   259 ELAERYAAARERLAELEYLRAALRL-WFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELeAQIRGNGG 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  311 QvclsdvcilRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLD-------QDINELQTQVRALQDKEEQQEAvnsQQQE 383
Cdd:COG4913   338 D---------RLEQLEREIERLERELEERERRRARLEALLAALGlplpasaEEFAALRAEAAALLEALEEELE---ALEE 405

                         170       180       190
                  ....*....|....*....|....*....|..
gi 117676405  384 ALRKQLERERRKCEEYvksnQELSEKLSNLQQ 415
Cdd:COG4913   406 ALAEAEAALRDLRREL----RELEAEIASLER 433
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 133-422 4.49e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.57  E-value: 4.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  133 DLQRAREHNQRLDEeilALRNRVRSLDSEKKVLGEMyltsgEKTSCQHQGELRELRQNLRRLQiLCNSAEKELRYERGRS 212
Cdd:pfam17380 307 EKAREVERRRKLEE---AEKARQAEMDRQAAIYAEQ-----ERMAMERERELERIRQEERKRE-LERIRQEEIAMEISRM 377

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  213 LDLKQHNSLLQEENIKIKIELKQAQE-KLLDNARlhSSLTAEWKHCQQKVKElELEGLRQTQSLKSQQGLQEKLAREKSK 291
Cdd:pfam17380 378 RELERLQMERQQKNERVRQELEAARKvKILEEER--QRKIQQQKVEMEQIRA-EQEEARQREVRRLEEERAREMERVRLE 454

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  292 AAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEA---KSIEARLQQQCQEEQQRRILLdqdiNELQTQVRALQ 368
Cdd:pfam17380 455 EQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKileKELEERKQAMIEEERKRKLLE----KEMEERQKAIY 530

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 117676405  369 DKEEQQEAvnsqqQEALRKQLE-RERRKCEEYVKSNQELSEKLSNLQQEKEALWQ 422
Cdd:pfam17380 531 EEERRREA-----EEERRKQQEmEERRRIQEQMRKATEERSRLEAMEREREMMRQ 580
46 PHA02562
endonuclease subunit; Provisional
 353-481 8.12e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 8.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 353 LDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKE-------ALWQEHG 425
Cdd:PHA02562 186 LDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEdpsaalnKLNTAAA 265

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 117676405 426 RF---LEQLGDHVRNYKDKHHC---------HKAKLQKVKDR---LTHELEIRNKRIKELE---DETGKLQQKI 481
Cdd:PHA02562 266 KIkskIEQFQKVIKMYEKGGVCptctqqiseGPDRITKIKDKlkeLQHSLEKLDTAIDELEeimDEFNEQSKKL 339
PTZ00121 PTZ00121
MAEBL; Provisional
 79-490 9.85e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 9.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   79 AQKLEASLEEIHRGAREPREEREQRTLGDalENARLEIEKLKDNLMKLKESGTTDLQRAREHNQRLD------EEILALR 152
Cdd:PTZ00121 1317 ADEAKKKAEEAKKKADAAKKKAEEAKKAA--EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADaakkkaEEKKKAD 1394

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  153 NRVRSLDSEKKVLGEMYLTSGEKTSCQhqgELRELRQNLRRLQILCNSAEKELRYERGRsldlKQHNSLLQEENIKIKIE 232
Cdd:PTZ00121 1395 EAKKKAEEDKKKADELKKAAAAKKKAD---EAKKKAEEKKKADEAKKKAEEAKKADEAK----KKAEEAKKAEEAKKKAE 1467

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  233 LKQAQEKL---LDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQE----KILDLQQK 305
Cdd:PTZ00121 1468 EAKKADEAkkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKadeaKKAEEKKK 1547

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  306 LDHGRQVC-LSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQ--- 381
Cdd:PTZ00121 1548 ADELKKAEeLKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElkk 1627

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  382 QEALRKQLERERRKCEEYVKSNQEL--SEKLSNLQQEKEALWQEHG---------------RFLEQLGDHVRNYKDKHHC 444
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDkkkaeeakkaeedekKAAEALKKEAEEAKKAEEL 1707

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 117676405  445 HKAKLQKVK--DRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQ 490
Cdd:PTZ00121 1708 KKKEAEEKKkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE 1755
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
258-463 1.15e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  258 QQKVKELE-LEGLRQT-QSLKSQQGLQEKLaREKSKAAEAQEKILDLQQKLDHGRQvclsdvcilRKKQLEEEIKEAKSI 335
Cdd:COG4913   248 REQIELLEpIRELAERyAAARERLAELEYL-RAALRLWFAQRRLELLEAELEELRA---------ELARLEAELERLEAR 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  336 EARLQQQCQEEQQRRILLD-QDINELQTQVRALQDKEEQQEAVNSQQQEALR----------KQLERERRKCEEYVKSNQ 404
Cdd:COG4913   318 LDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAalglplpasaEEFAALRAEAAALLEALE 397

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 117676405  405 ELSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIR 463
Cdd:COG4913   398 EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLD 456
PTZ00121 PTZ00121
MAEBL; Provisional
 201-583 1.16e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 1.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  201 AEKELRYERGRSL-DLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQ 279
Cdd:PTZ00121 1208 AEEERKAEEARKAeDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAE 1287

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  280 glqEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSdvcilrKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINE 359
Cdd:PTZ00121 1288 ---EKKKADEAKKAEEKKKADEAKKKAEEAKKADEA------KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADE 1358

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  360 LQ-TQVRALQDKEEQQEAvnSQQQEALRKQLErERRKCEEYVKSNQELSEKLSNLQQEKEAlwQEHGRFLEQLGDHVRNY 438
Cdd:PTZ00121 1359 AEaAEEKAEAAEKKKEEA--KKKADAAKKKAE-EKKKADEAKKKAEEDKKKADELKKAAAA--KKKADEAKKKAEEKKKA 1433

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405  439 -------KDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEME----KVFQGQIMAQNDILLLEKRKLLE 507
Cdd:PTZ00121 1434 deakkkaEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADeakkKAEEAKKKADEAKKAAEAKKKAD 1513

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 117676405  508 QVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRREEETVITDNAAFEILKKI 583
Cdd:PTZ00121 1514 EAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKA 1589
PRK12704 PRK12704
phosphodiesterase; Provisional
 322-484 1.53e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 1.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 322 KKQLEEEIKEAKSI-EARLQQQCQEEQQRRILLDQDI----NELQTQVRALQDKEEQqeavnsqqqeaLRKQLERERRKC 396
Cdd:PRK12704  41 KRILEEAKKEAEAIkKEALLEAKEEIHKLRNEFEKELrerrNELQKLEKRLLQKEEN-----------LDRKLELLEKRE 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 397 EEYVKSNQELSEKLSNLQQEKEalwqehgrfleqlgdhvrNYKDKHHCHKAKLQKVKdRLTHElEIRNKRIKELEDET-- 474
Cdd:PRK12704 110 EELEKKEKELEQKQQELEKKEE------------------ELEELIEEQLQELERIS-GLTAE-EAKEILLEKVEEEArh 169

                        170
                 ....*....|..
gi 117676405 475 --GKLQQKIEME 484
Cdd:PRK12704 170 eaAVLIKEIEEE 181
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
232-431 3.24e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.52  E-value: 3.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 232 ELKQAQEKLLD-NARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGR 310
Cdd:COG4717   50 RLEKEADELFKpQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 311 QvclsdvcILRKKQLEEEIKEaksIEARLQQqcqeeqqrrilLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLE 390
Cdd:COG4717  130 L-------YQELEALEAELAE---LPERLEE-----------LEERLEELRELEEELEELEAELAELQEELEELLEQLSL 188

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 117676405 391 RERRKCEEYVKSNQELSEKLSNLQQEKEALWQEHGRFLEQL 431
Cdd:COG4717  189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEL 229
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 181-494 9.25e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 39.18  E-value: 9.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   181 QGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQK 260
Cdd:pfam02463  667 SLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKID 746

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   261 VKELELEGLRQtQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGRQVCLSDVCILRKKQLEEEIKEAKSIEARLQ 340
Cdd:pfam02463  747 EEEEEEEKSRL-KKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIE 825

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   341 QQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQEALRKQLERERRKCEEYVKSNQELSEKLSNLQQEKEAL 420
Cdd:pfam02463  826 QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEE 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405   421 wqehGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHEL--------EIRNKRIKELEDETGKLQQKIEMEKVFQGQIM 492
Cdd:pfam02463  906 ----SQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLleeadekeKEENNKEEEEERNKRLLLAKEELGKVNLMAIE 981


                   ..
gi 117676405   493 AQ 494
Cdd:pfam02463  982 EF 983
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 222-431 9.89e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.59  E-value: 9.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 222 LQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELEleglrqtqslKSQQGLQEKLAREKSKAAEAQEKILD 301
Cdd:COG4942   25 AEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA----------RRIRALEQELAALEAELAELEKEIAE 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 117676405 302 LQQKLDHGRQVCLSDVCILRKKQLEEEIK------EAKSIEARLQQQCQEEQQRRILLDQ---DINELQTQVRALQDKEE 372
Cdd:COG4942   95 LRAELEAQKEELAELLRALYRLGRQPPLAlllspeDFLDAVRRLQYLKYLAPARREQAEElraDLAELAALRAELEAERA 174

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 117676405 373 QQEAVNSQQQEAlRKQLERERRKCEEYVksnQELSEKLSNLQQEKEALWQEHGRFLEQL 431
Cdd:COG4942  175 ELEALLAELEEE-RAALEALKAERQKLL---ARLEKELAELAAELAELQQEAEELEALI 229
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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