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Conserved domains on  [gi|1184181438|gb|OSC28076|]
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camphor resistance protein CrcB [Mycobacterium vulneris]

Protein Classification

fluoride efflux transporter CrcB( domain architecture ID 10014631)

fluoride efflux transporter CrcB is important for reducing fluoride concentration in the cell, thus reducing its toxicity

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14228 PRK14228
fluoride efflux transporter CrcB;
10-127 8.35e-54

fluoride efflux transporter CrcB;


:

Pssm-ID: 237643  Cd Length: 122  Bit Score: 164.53  E-value: 8.35e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14228    5 LVWIGVMLIGGIGSVLRFLVDRTVARRLARTFPYGTLAVNVSGAALLGFLAGLALPKDAALLAGTAFVGAYTTFSTWMLE 84

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14228   85 TQRLGEERQMRSALANIVVSVVLGLAAALLGQWLAQLL 122
 
Name Accession Description Interval E-value
PRK14228 PRK14228
fluoride efflux transporter CrcB;
10-127 8.35e-54

fluoride efflux transporter CrcB;


Pssm-ID: 237643  Cd Length: 122  Bit Score: 164.53  E-value: 8.35e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14228    5 LVWIGVMLIGGIGSVLRFLVDRTVARRLARTFPYGTLAVNVSGAALLGFLAGLALPKDAALLAGTAFVGAYTTFSTWMLE 84

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14228   85 TQRLGEERQMRSALANIVVSVVLGLAAALLGQWLAQLL 122
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 11-127 9.95e-28

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 98.63  E-value: 9.95e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  11 VWVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFST 85
Cdd:COG0239     3 TLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLarrglLSPELRLLLGTGFLGGFTTFST 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1184181438  86 WMLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:COG0239    83 FSLETVRLLERGRYLLALLYVLLSVVLGLLAAALGLALARRL 124
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 15-119 4.99e-22

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 83.68  E-value: 4.99e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRpFPFGTLAVNISGAALLGFLGGMALNK----DVALLAGTAFAGAYTTFSTWMLET 90
Cdd:pfam02537   2 VALGGALGALLRYLLSLLNPRLAGG-FPLGTLAVNVLGSFLLGLLAGLLLERghspELRLLLGTGFCGGLTTFSTFSLET 80

                          90       100
                  ....*....|....*....|....*....
gi 1184181438  91 QRLGEERQLRAALANIVVSVLLGETAAFI 119
Cdd:pfam02537  81 LTLLRAGQYLLALLYVLLSVVLGLAAVVL 109
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 14-124 4.18e-14

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 63.56  E-value: 4.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  14 GVALIGGIGSVLRFVVD-RTVARRLSRPFPFGTLAVNISGAALLGFLGGMAL----NKDVALLAGTAFAGAYTTFSTWML 88
Cdd:TIGR00494   2 AIFLGGGPGALLRYLLGiFISAGLFGNSLPLGTLTVNIIGCFGIGFVTLFTQpaviSPDLKLLIGTGFLGGFTTFSTFSL 81

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1184181438  89 ETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLA 124
Cdd:TIGR00494  82 ETTSLLQEGQLGEAVLYILGTLGGGLIGVALGWLLA 117
 
Name Accession Description Interval E-value
PRK14228 PRK14228
fluoride efflux transporter CrcB;
10-127 8.35e-54

fluoride efflux transporter CrcB;


Pssm-ID: 237643  Cd Length: 122  Bit Score: 164.53  E-value: 8.35e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14228    5 LVWIGVMLIGGIGSVLRFLVDRTVARRLARTFPYGTLAVNVSGAALLGFLAGLALPKDAALLAGTAFVGAYTTFSTWMLE 84

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14228   85 TQRLGEERQMRSALANIVVSVVLGLAAALLGQWLAQLL 122
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 11-127 9.95e-28

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 98.63  E-value: 9.95e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  11 VWVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFST 85
Cdd:COG0239     3 TLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLarrglLSPELRLLLGTGFLGGFTTFST 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1184181438  86 WMLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:COG0239    83 FSLETVRLLERGRYLLALLYVLLSVVLGLLAAALGLALARRL 124
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 15-119 4.99e-22

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 83.68  E-value: 4.99e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRpFPFGTLAVNISGAALLGFLGGMALNK----DVALLAGTAFAGAYTTFSTWMLET 90
Cdd:pfam02537   2 VALGGALGALLRYLLSLLNPRLAGG-FPLGTLAVNVLGSFLLGLLAGLLLERghspELRLLLGTGFCGGLTTFSTFSLET 80

                          90       100
                  ....*....|....*....|....*....
gi 1184181438  91 QRLGEERQLRAALANIVVSVLLGETAAFI 119
Cdd:pfam02537  81 LTLLRAGQYLLALLYVLLSVVLGLAAVVL 109
PRK14232 PRK14232
fluoride efflux transporter CrcB;
15-125 1.77e-15

fluoride efflux transporter CrcB;


Pssm-ID: 237644  Cd Length: 120  Bit Score: 67.11  E-value: 1.77e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLG 94
Cdd:PRK14232    6 VGIGGAFGSLARYQLGKVISKKSKSTFPVGTFIINITGAILLGIVSSSNISKNMYLLLGDGFLGAYTTFSTFMYEGFNLF 85

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1184181438  95 EERQLRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14232   86 QEKEKLNAFIYILGSLIIGIIGYILGFWIGN 116
PRK14195 PRK14195
fluoride efflux transporter CrcB;
15-127 5.99e-15

fluoride efflux transporter CrcB;


Pssm-ID: 184563  Cd Length: 125  Bit Score: 65.83  E-value: 5.99e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGG-----MALNKDVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14195    7 VAAGGALGSVARYLVGVGALRLMGPAFPWGTLAVNVTGSFLIGVLAGllahrWNASQEWRLFLIVGVLGGFTTFSAFSLD 86

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14195   87 AALLIERGAYGAAAAYIAASVVLSVAALFAGLAIARAL 124
PRK14205 PRK14205
fluoride efflux transporter CrcB;
15-123 1.08e-14

fluoride efflux transporter CrcB;


Pssm-ID: 172693  Cd Length: 118  Bit Score: 65.21  E-value: 1.08e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLG 94
Cdd:PRK14205    7 VATGGFFGAITRFAISNWFKKRNKTSFPIATFLINITGAFLLGYIIGNGVTTGWQLLLGTGFMGAFTTFSTFKLESVQLL 86

                          90       100
                  ....*....|....*....|....*....
gi 1184181438  95 EERQLRAALANIVVSVLLGETAAFIGQQL 123
Cdd:PRK14205   87 NRKNFSTFLLYLSATYIVGILFAFLGMKL 115
PRK14212 PRK14212
fluoride efflux transporter CrcB;
15-127 4.04e-14

fluoride efflux transporter CrcB;


Pssm-ID: 184569  Cd Length: 128  Bit Score: 64.06  E-value: 4.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14212    7 LAAGGALGAVSRYGLNNLTVKLLGDSFPYGTLIVNCLGCFVLGFLMQWGfssdsHNTHLKLMLTAGFLGAFTTFSTFSYE 86

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14212   87 TLDCFKAGDYFNGFSNILANVLLGLLMVFIGAYLGSLL 124
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 14-124 4.18e-14

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 63.56  E-value: 4.18e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  14 GVALIGGIGSVLRFVVD-RTVARRLSRPFPFGTLAVNISGAALLGFLGGMAL----NKDVALLAGTAFAGAYTTFSTWML 88
Cdd:TIGR00494   2 AIFLGGGPGALLRYLLGiFISAGLFGNSLPLGTLTVNIIGCFGIGFVTLFTQpaviSPDLKLLIGTGFLGGFTTFSTFSL 81

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1184181438  89 ETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLA 124
Cdd:TIGR00494  82 ETTSLLQEGQLGEAVLYILGTLGGGLIGVALGWLLA 117
PRK14222 PRK14222
fluoride efflux transporter CrcB;
13-127 9.54e-14

fluoride efflux transporter CrcB;


Pssm-ID: 172710  Cd Length: 124  Bit Score: 62.81  E-value: 9.54e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  13 VGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGF-----LGGMALNKDVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14222    5 VYIALFGALGCLARYYLSGWVYALFGRAFPYGTLAVNVIGAFLIGLimefsLRSTLIPPTLRIGLTIGFLGGLTTFSTFS 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14222   85 YETFRLLEDGELLIASVNVLASVVVCLVCTWLGIMTARAL 124
PRK14214 PRK14214
fluoride efflux transporter CrcB;
15-123 1.50e-13

fluoride efflux transporter CrcB;


Pssm-ID: 184571  Cd Length: 118  Bit Score: 62.19  E-value: 1.50e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLG 94
Cdd:PRK14214    8 VGFGAALGAMLRYGISVLVKSKWKTNFPYATFFINITGSFLLGFLVSSALGPVWQLFLGTGFMGGYTTFSTFKVESMELK 87

                          90       100
                  ....*....|....*....|....*....
gi 1184181438  95 EERQLRAALANIVVSVLLGETAAFIGQQL 123
Cdd:PRK14214   88 WKTNYRVLFSYLGCTYVFGLIAAFLGMML 116
PRK14197 PRK14197
fluoride efflux transporter CrcB;
12-123 4.57e-13

fluoride efflux transporter CrcB;


Pssm-ID: 172685  Cd Length: 124  Bit Score: 60.93  E-value: 4.57e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  12 WVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMA----LNKDVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14197    4 VLFVALGGSIGAVLRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGqmshVSPELKALIGVGLLGALTTFSTFS 83

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQL 123
Cdd:PRK14197   84 NETLLLMQEGAWLKAALNVVLNLSLCLFMVYLGQQL 119
PRK14203 PRK14203
fluoride efflux transporter CrcB;
15-127 8.36e-13

fluoride efflux transporter CrcB;


Pssm-ID: 237639  Cd Length: 132  Bit Score: 60.60  E-value: 8.36e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNK-------DVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14203   11 VALGSVLGGPARFFLSGLVARRIGETFPWGTLTVNVSGAFAIGIFGALAASGhglfalpAPWLFAVTGFLGCYTTVSSFS 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14203   91 LQTLTLARDGEFLRALGNVAFSLILCLIAVAIGFAAATGL 130
PRK14211 PRK14211
fluoride efflux transporter CrcB;
15-123 1.40e-12

fluoride efflux transporter CrcB;


Pssm-ID: 172699  Cd Length: 114  Bit Score: 59.56  E-value: 1.40e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRlsRPFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLG 94
Cdd:PRK14211    6 VALGGALGATTRYLTGRYVDSY--RSFPVATFLVNVAGCLILGLLSGASLSTQTFALLGTGFCGGLTTYSTFAVESVGLL 83

                          90       100
                  ....*....|....*....|....*....
gi 1184181438  95 EERQLRAALANIVVSVLLGETAAFIGQQL 123
Cdd:PRK14211   84 RIRQALLSVVYIVASVAAGLAAAWLGFRL 112
PRK14227 PRK14227
fluoride efflux transporter CrcB;
12-127 1.48e-11

fluoride efflux transporter CrcB;


Pssm-ID: 172715  Cd Length: 124  Bit Score: 57.15  E-value: 1.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  12 WVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGF-----LGGMALNKDVALLAGTAFAGAYTTFSTW 86
Cdd:PRK14227    4 YIVVAIGGSIGAILRYFTGVYSAKNLGLDFPYGTLIVNSVGSFILSFfmilfLEKLSLDPLWRLFVAVGFCGSFTTFSSF 83

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1184181438  87 MLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14227   84 TYETIALFQDGDYTKAMLNIILNNVLSITSAFSGIVLARVL 124
PRK14206 PRK14206
fluoride efflux transporter CrcB;
15-124 1.63e-11

fluoride efflux transporter CrcB;


Pssm-ID: 172694  Cd Length: 127  Bit Score: 57.12  E-value: 1.63e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFL-------GGMALNKDVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14206    6 IALGSALGGTLRFWLSGLVAEATGGTFPWGTLVINVSGSFLIGFFatltgpeGRVFVGESWRLFVMVGVCGGFTTFSSFS 85

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLA 124
Cdd:PRK14206   86 LQTLNLARDGDWLRAGGNVVLSVVFCLLAVWLGHVAA 122
PRK14207 PRK14207
fluoride efflux transporter CrcB;
15-126 7.17e-11

fluoride efflux transporter CrcB;


Pssm-ID: 172695  Cd Length: 123  Bit Score: 55.52  E-value: 7.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVArrLSRPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14207    9 VAIGGGLGALARYYISGLLP--VYKDFPVGTLLVNSIASFILGYLYGLLfwgfdVSPEWRAFLGTGFCGGLSTFSTFSYE 86

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQ 126
Cdd:PRK14207   87 TFSLLREREYLLALLNISANVLITISLVFLGFILARR 123
PRK14223 PRK14223
fluoride efflux transporter CrcB;
18-124 1.16e-10

fluoride efflux transporter CrcB;


Pssm-ID: 184576  Cd Length: 122  Bit Score: 54.69  E-value: 1.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  18 IGG-IGSVLRFVVDRTVARRLSrpFPFGTLAVNISGAALLGFLGGMALNKDVA----LLAGTAFAGAYTTFSTWMLETQR 92
Cdd:PRK14223    9 IGGfFGAILRYLISGIIPVKFG--IPTGTLIVNLIGSFILGFLLYSSLFGSISpeyrLFIITGFCGALTTFSTFSYETFS 86

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1184181438  93 LGEERQLRAALANIVVSVLLGETAAFIGQQLA 124
Cdd:PRK14223   87 LLEEGLYIKALLNILLNVFGCLIMIYFGRVLS 118
PRK14234 PRK14234
fluoride efflux transporter CrcB;
13-125 1.20e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172722  Cd Length: 124  Bit Score: 54.78  E-value: 1.20e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  13 VGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKD---VALLAG--TAFAGAYTTFSTWM 87
Cdd:PRK14234    6 LAVSAGGIAGTLLRFATGNWVSANWPRHFYAATLAVNIVGCLLIGLLYGLFLLRPevpIELRAGliVGFLGGLTTFSSFS 85

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14234   86 LDTLRLLESGQVPLALGYAGISVFGGLLATWAGLSLTR 123
PRK14233 PRK14233
fluoride efflux transporter CrcB;
15-120 3.59e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172721  Cd Length: 133  Bit Score: 53.73  E-value: 3.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVAL-------LAGTAFAGAYTTFSTWM 87
Cdd:PRK14233    9 VLVGGFIGGVMRFFLSGYVGRRIGETFPWGTFVVNVSGAFVIGTAAGLGARLGGIFsttifheFIMVGLLGGYTTVSSFC 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIG 120
Cdd:PRK14233   89 LQSVNLMLDGEQRQALFNIVASALLCVLAVAAG 121
PRK14199 PRK14199
fluoride efflux transporter CrcB;
15-125 4.62e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172687  Cd Length: 128  Bit Score: 53.24  E-value: 4.62e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLggMALNKDVALLAG-------TAFAGAYTTFSTWM 87
Cdd:PRK14199   10 VGLGGFIGASLRYLISIFAAKMFNGNFPYGTLIVNIVGALLIGFI--MEFSMDTALISSnmklfltTGIMGGLTTFSTFS 87

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14199   88 YETINLITNGNILLGIENIILNLGLSLLGVVIGQKLAR 125
PRK14213 PRK14213
camphor resistance protein CrcB; Provisional
 13-110 9.53e-10

camphor resistance protein CrcB; Provisional


Pssm-ID: 184570  Cd Length: 118  Bit Score: 52.13  E-value: 9.53e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  13 VGVALIGGIGSVLRFVVDRTVARRLSR-PFPFGTLAVNISGAALLGFLGGMAL-NKDVALLAGTAFAGAYTTFSTWMLET 90
Cdd:PRK14213    4 AGIFIAGGIGAVLRFWLGNVITAKTKGlSLPIGIMTVNILGSFGLGIFTGLGVdNASVSIIIGTGFFGAFTTFSTFSVEA 83

                          90       100
                  ....*....|....*....|
gi 1184181438  91 QRLGEERQLRAALANIVVSV 110
Cdd:PRK14213   84 VQLLMAKRVKESILYIALTL 103
PRK14198 PRK14198
fluoride efflux transporter CrcB;
10-127 1.14e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172686  Cd Length: 124  Bit Score: 52.06  E-value: 1.14e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGvaliGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGM-----ALNKDVALLAGTAFAGAYTTFS 84
Cdd:PRK14198    5 LVFVG----GGLGASLRHAVNMASARLLGTSFPYGTFIINVSGSLVMGLIAGYlafkgGAPQHWRLFLMTGILGGYTTFS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1184181438  85 TWMLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14198   81 AFSLDAALLYERGALGLAALYVLGSVALGIAGLFAGLALIRHF 123
PRK14204 PRK14204
fluoride efflux transporter CrcB;
10-127 2.09e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172692  Cd Length: 127  Bit Score: 51.46  E-value: 2.09e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGVALIGGIGSVLRFVVDRTVARR--LSRPFPFGTLAVNISGAALLGFLGGMALNK----DVALLAGTAFAGAYTTF 83
Cdd:PRK14204    3 FVFLWAALGGAIGSSLRYFVGKMMPSKflMFESFPLGTFSVNIIGCFVIGFMGHLAAKKvfgdDFGIFFVTGVLGGFTTF 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1184181438  84 STWMLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14204   83 SSYGLDTLKLLQKSQYIEAISYVLGTNLLGLIGVAIGWFLAKNF 126
PRK14200 PRK14200
fluoride efflux transporter CrcB;
15-123 2.38e-09

fluoride efflux transporter CrcB;


Pssm-ID: 237638  Cd Length: 127  Bit Score: 51.34  E-value: 2.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKDVAL-----LAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14200   10 IALGGAFGACSRYLVSELCVVLLGRGFPYGTLTVNVVGSFIMGLLIAAFENELLATepwrqIIGLGFLGALTTFSTFSMD 89

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQL 123
Cdd:PRK14200   90 NVLLMQQGAFFKMGLNVLLNVVLSISAAWIGFQL 123
PRK14202 PRK14202
fluoride efflux transporter CrcB;
19-125 2.43e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172690  Cd Length: 128  Bit Score: 51.64  E-value: 2.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  19 GGIGSVLRFVVDRTVARrLSRPFPFGTLAVNISGAALLGFLGGMALNK-----DVALLAGTAFAGAYTTFSTWMLETQRL 93
Cdd:PRK14202   15 GFLGSVARYLVALALSF-IGTGFPFATFTVNLLGSFLIGFISELALSTtlvspEARLLLVTGFCGGFTTFSSYMYEIAAL 93

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1184181438  94 GEERQLRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14202   94 LRDGELFYASLYLAGSLVGGFVALYSGTLLAK 125
PRK14224 PRK14224
fluoride efflux transporter CrcB;
14-127 6.57e-09

fluoride efflux transporter CrcB;


Pssm-ID: 237642  Cd Length: 126  Bit Score: 50.16  E-value: 6.57e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  14 GVALIGGIGSVLRFVVDRTVarrlsrPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFSTWML 88
Cdd:PRK14224   13 LIGAGGFLGAICRFLICELI------EGQLGTLSVNVLGSFMLGMIMYDTeyigfIGPKGRLAFGTGFLGAFTTFSTFAV 86

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1184181438  89 ETQRLgeerQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14224   87 QSFSM----PFVPALGNISANLFLTLTGVFFGRSLIKAL 121
PRK14220 PRK14220
fluoride efflux transporter CrcB;
21-125 2.21e-08

fluoride efflux transporter CrcB;


Pssm-ID: 237641  Cd Length: 120  Bit Score: 48.62  E-value: 2.21e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  21 IGSVLRFVVDRTVARRLSRP--FPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLGEERQ 98
Cdd:PRK14220   12 IGAMLRYAITNYGKKHWEQFsnLPTPTLLINLTGAFILGLIFGRKFNPFIYALLGTGVLGGYTTFSTLNTELVSLYKSKN 91

                          90       100
                  ....*....|....*....|....*..
gi 1184181438  99 LRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14220   92 YRVLKLYALLSYLGGLILVFCGYYLGS 118
PRK14210 PRK14210
fluoride efflux transporter CrcB;
15-127 2.40e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172698  Cd Length: 127  Bit Score: 48.85  E-value: 2.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLS---RPFPFGTLAVNISGAALLGFLGGMA----LNKDVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14210    7 IFIGGGMGSVTRYLTQIAVNERLSpalFPFPWGTFAVNIIGSLLIGFFYSFSerfnLSFELRLFLTVGFCGGFTTFSTLA 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14210   87 NDSLSLLKGGFYGIFTFYVFISILLGLLAVLAGGYLGEQF 126
PRK14215 PRK14215
fluoride efflux transporter CrcB;
13-127 5.76e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172703  Cd Length: 126  Bit Score: 47.90  E-value: 5.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  13 VGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14215    5 LAIAVGAAIGANLRYGIGLWAAQRWGTSWPYGTFIINLLGCLLIGLLLTLAttrltLSEPARLMLVTGLLGGFTTFSTFG 84

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14215   85 YESYSLLSSGNWLAAGGYVVGSVGGGLIAVIIGAGLGRWL 124
PRK14208 PRK14208
fluoride efflux transporter CrcB;
15-127 8.86e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172696  Cd Length: 126  Bit Score: 47.26  E-value: 8.86e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNK-----DVALLAGTAFAGAYTTFSTWMLE 89
Cdd:PRK14208    7 VCLGGALGSGARYLTSAWALRAFGPDFPRGTLLVNVSGSFLLAGIMTASLQSeavppDLRLFLAAGVMGGFTTYSSFNYE 86

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14208   87 TLALLEQGRLAAAAAYLLATVLGCLAAAFAATLLVRWL 124
PRK14219 PRK14219
fluoride efflux transporter CrcB;
10-127 4.49e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172707  Cd Length: 132  Bit Score: 45.61  E-value: 4.49e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMA-----LNKDVALLAGTAFAGAYTTFS 84
Cdd:PRK14219    1 LIYIIVGIAGILGALSRYYLGLTIHEFWHHTFPLATLLINLAGCFLLAWLTTYIaklniLPSDVITGIGTGFIGSFTTFS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1184181438  85 TWMLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14219   81 TFSVETIQLINHSEWSIAFLYVSCSILGGLIMSGLGYTLGDFL 123
PRK14216 PRK14216
fluoride efflux transporter CrcB;
41-126 1.67e-06

fluoride efflux transporter CrcB;


Pssm-ID: 184572  Cd Length: 132  Bit Score: 44.06  E-value: 1.67e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  41 FPFGTLAVNISGAALLGF-----LGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLGEERQLRAALANIVVSVLLGET 115
Cdd:PRK14216   37 WPWPTFTVNVVGAFLLGYfttrlLERLPLSSYRRPLLGTGLCGGLTTFSTMQVETIRMIEHGHWGLAAGYTAASIAAGLL 116

                          90
                  ....*....|.
gi 1184181438 116 AAFIGQQLAQQ 126
Cdd:PRK14216  117 AVHLATVLVRR 127
PRK14209 PRK14209
fluoride efflux transporter CrcB;
15-125 1.69e-06

fluoride efflux transporter CrcB;


Pssm-ID: 237640  Cd Length: 124  Bit Score: 43.77  E-value: 1.69e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFLGGMALNKD--VALLAGTAFAGAYTTFSTWMLETQR 92
Cdd:PRK14209    8 VALGGALGASARYLTNVGSMRLFGPAFPVGTMIVNVVGSFLMGVLVVVLAHKGnrYAPFLMTGMLGGFTTFSAFSLDAVT 87

                          90       100       110
                  ....*....|....*....|....*....|...
gi 1184181438  93 LGEERQLRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14209   88 LYERGQAGLAAAYVGLSVGLSLAGLMAGMAAVR 120
PRK14217 PRK14217
fluoride efflux transporter CrcB;
12-125 2.64e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172705  Cd Length: 134  Bit Score: 43.45  E-value: 2.64e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  12 WVGVALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGF-----LGGMALNKDVALLAGTAFAGAYTTFSTW 86
Cdd:PRK14217    6 YLAVAIGGSLGAMSRYLVTIMAQNAWGIKFPYGTLLVNTLGSFLAGFflivlVGRFSAEESFRLFLFTGFLGAFTTFSSF 85

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1184181438  87 MLETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQ 125
Cdd:PRK14217   86 AAESLFMFEQGYWFKLITNILVNNVGSLSMVFIGTLVAK 124
PRK14231 PRK14231
fluoride efflux transporter CrcB;
15-127 6.74e-05

fluoride efflux transporter CrcB;


Pssm-ID: 184579  Cd Length: 129  Bit Score: 39.83  E-value: 6.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVArrlSRPFPFGTLAVNISGAALLGFLGGMALNKDVALLA-----GTAFAGAYTTFSTWMLE 89
Cdd:PRK14231    6 VGVFGALGGMCRYAMNLWLG---GGDFPSATLAVNLIGCFLLAFLMQFLAEKSRISLVilngiGTGFIGAFTTFSAFSVD 82

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1184181438  90 TQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14231   83 TIQLVQSGAWLLAVSYVLASFIGGLIMVKFGRMLSNKL 120
PRK14229 PRK14229
fluoride efflux transporter CrcB;
20-120 7.57e-05

fluoride efflux transporter CrcB;


Pssm-ID: 172717  Cd Length: 108  Bit Score: 39.05  E-value: 7.57e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  20 GIGSVLRFVVDRTVARRLsrpFPFGTLAVNISGAALLGFLGGMALNKDVALLAGTAFAGAYTTFSTWMLETQRLGEERql 99
Cdd:PRK14229   10 GLGALVRYFFSRYNQASK---LPLGTLIANLLGCFLIGVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDK-- 84

                          90       100
                  ....*....|....*....|.
gi 1184181438 100 RAALANIVVSVLLGETAAFIG 120
Cdd:PRK14229   85 KVFYSYLTLTYIGGLVAIFLG 105
PRK14221 PRK14221
fluoride efflux transporter CrcB;
13-93 6.75e-04

fluoride efflux transporter CrcB;


Pssm-ID: 184575  Cd Length: 124  Bit Score: 37.09  E-value: 6.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  13 VGVALIGGIGSVLRFVVDRTVArrLSRPFPFGTLAVNISGAALL-----GFLGGMALNKDVALLAGTAFAGAYTTFSTWM 87
Cdd:PRK14221    9 LGIFLAAMLGGLVRYLVSTWLP--ASPDFPWGTLFVNYLGIFCLiylvkGYLVYKGTSKGLILALGTGFCGGLTTFSSLM 86


                  ....*.
gi 1184181438  88 LETQRL 93
Cdd:PRK14221   87 LDTVKL 92
PRK14226 PRK14226
fluoride efflux transporter CrcB;
10-120 7.03e-04

fluoride efflux transporter CrcB;


Pssm-ID: 172714  Cd Length: 130  Bit Score: 36.78  E-value: 7.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  10 LVWVGVALIGGIGSVLRFVVDRTVARrLSRPFPFGTLAVNISGAALLGFLGGMAL-----NKDVA----LLAGTAFAGAY 80
Cdd:PRK14226    3 LLLLLVGIGGGFGAMARFALTQATAS-ISKQIPLGILLCNIIGSLIIGMMAAFLIetklfNEDVStyvrFLLVTGFLGGF 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1184181438  81 TTFSTWMLETQRLGEERQLRAALANIVVSVLLGETAAFIG 120
Cdd:PRK14226   82 TTFSSFSLDILNLLQRGEIFIAIGYIMVSVLASLIAVILG 121
PRK14218 PRK14218
fluoride efflux transporter CrcB;
15-127 1.15e-03

fluoride efflux transporter CrcB;


Pssm-ID: 184573  Cd Length: 133  Bit Score: 36.40  E-value: 1.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1184181438  15 VALIGGIGSVLRFVVDRTVARRLSRPFPFGTLAVNISGAALLGFL-------GGMALNKDVALLAGtaFAGAYTTFSTWM 87
Cdd:PRK14218   13 VMLGGAFGSGLRFVIGSCLLQRFGAGFPWGTLAVNLIGSFVAGFLliwldkrGSAGWPWRMLLIVG--LIGGLTTFSSLM 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1184181438  88 LETQRLGEERQLRAALANIVVSVLLGETAAFIGQQLAQQL 127
Cdd:PRK14218   91 MECLVFVRSDRSLMVGIYLCITLLFGLLFVFLGARLGAFV 130
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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