RecName: Full=ATP synthase subunit epsilon, mitochondrial; Short=ATPase subunit epsilon
Protein Classification
ATP synthase subunit epsilon family protein( domain architecture ID 10519197)
ATP synthase subunit epsilon family protein similar to human ATP synthase subunit epsilon, part of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| ATP-synt_Eps | pfam04627 | Mitochondrial ATP synthase epsilon chain; This family constitutes the mitochondrial ATP ... |
2-51 | 2.24e-15 | ||
Mitochondrial ATP synthase epsilon chain; This family constitutes the mitochondrial ATP synthase epsilon subunit. This is not to be confused with the bacterial epsilon subunit, which is homologous to the mitochondrial delta subunit (pfam00401 and pfam02823) The epsilon subunit is located in the extrinsic membrane section F1, which is the catalytic site of ATP synthesis. The epsilon subunit was not well ordered in the crystal structure of bovine F1, but it is known to be located in the stalk region of F1. E subunit is thought to be involved in the regulation of ATP synthase, since a null mutation increased oligomycin sensitivity and decreased inhibition by inhibitor protein IF1. : Pssm-ID: 461373 Cd Length: 49 Bit Score: 62.56 E-value: 2.24e-15
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| Name | Accession | Description | Interval | E-value | ||
| ATP-synt_Eps | pfam04627 | Mitochondrial ATP synthase epsilon chain; This family constitutes the mitochondrial ATP ... |
2-51 | 2.24e-15 | ||
Mitochondrial ATP synthase epsilon chain; This family constitutes the mitochondrial ATP synthase epsilon subunit. This is not to be confused with the bacterial epsilon subunit, which is homologous to the mitochondrial delta subunit (pfam00401 and pfam02823) The epsilon subunit is located in the extrinsic membrane section F1, which is the catalytic site of ATP synthesis. The epsilon subunit was not well ordered in the crystal structure of bovine F1, but it is known to be located in the stalk region of F1. E subunit is thought to be involved in the regulation of ATP synthase, since a null mutation increased oligomycin sensitivity and decreased inhibition by inhibitor protein IF1. Pssm-ID: 461373 Cd Length: 49 Bit Score: 62.56 E-value: 2.24e-15
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| F1-ATPase_epsilon | cd12153 | eukaryotic mitochondrial ATP synthase epsilon subunit; The F-ATPase is found in bacterial ... |
3-48 | 2.17e-10 | ||
eukaryotic mitochondrial ATP synthase epsilon subunit; The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes, and in chloroplast thylakoid membranes. It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient. The extrinsic membrane domain, F1, is composed of alpha, beta, gamma, delta, and epsilon subunits (only found in eukaryotes, lacking in bacteria) with a stoichiometry of 3:3:1:1:1. Alpha and beta subunit form the globular catalytic moiety, a hexameric ring of alternating subunits. Gamma, delta and epsilon subunits form a stalk, connecting F1 to F0, the integral membrane proton translocating domain.The epsilon subunit is thought to be involved in the regulation of ATP synthase, since a null mutation increased oligomycin sensitivity and decreased inhibition by inhibitor protein IF1. Pssm-ID: 213396 Cd Length: 45 Bit Score: 49.56 E-value: 2.17e-10
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| Name | Accession | Description | Interval | E-value | ||
| ATP-synt_Eps | pfam04627 | Mitochondrial ATP synthase epsilon chain; This family constitutes the mitochondrial ATP ... |
2-51 | 2.24e-15 | ||
Mitochondrial ATP synthase epsilon chain; This family constitutes the mitochondrial ATP synthase epsilon subunit. This is not to be confused with the bacterial epsilon subunit, which is homologous to the mitochondrial delta subunit (pfam00401 and pfam02823) The epsilon subunit is located in the extrinsic membrane section F1, which is the catalytic site of ATP synthesis. The epsilon subunit was not well ordered in the crystal structure of bovine F1, but it is known to be located in the stalk region of F1. E subunit is thought to be involved in the regulation of ATP synthase, since a null mutation increased oligomycin sensitivity and decreased inhibition by inhibitor protein IF1. Pssm-ID: 461373 Cd Length: 49 Bit Score: 62.56 E-value: 2.24e-15
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| F1-ATPase_epsilon | cd12153 | eukaryotic mitochondrial ATP synthase epsilon subunit; The F-ATPase is found in bacterial ... |
3-48 | 2.17e-10 | ||
eukaryotic mitochondrial ATP synthase epsilon subunit; The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes, and in chloroplast thylakoid membranes. It uses a proton gradient to drive ATP synthesis and hydrolyzes ATP to build the proton gradient. The extrinsic membrane domain, F1, is composed of alpha, beta, gamma, delta, and epsilon subunits (only found in eukaryotes, lacking in bacteria) with a stoichiometry of 3:3:1:1:1. Alpha and beta subunit form the globular catalytic moiety, a hexameric ring of alternating subunits. Gamma, delta and epsilon subunits form a stalk, connecting F1 to F0, the integral membrane proton translocating domain.The epsilon subunit is thought to be involved in the regulation of ATP synthase, since a null mutation increased oligomycin sensitivity and decreased inhibition by inhibitor protein IF1. Pssm-ID: 213396 Cd Length: 45 Bit Score: 49.56 E-value: 2.17e-10
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