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PilX3-4 (plasmid) [Escherichia coli]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
CagE_TrbE_VirB super family
cl40727 CagE, TrbE, VirB family, component of type IV transporter system; This family includes the ...
113-913
0e+00
CagE, TrbE, VirB family, component of type IV transporter system; This family includes the Helicobacter pylori protein CagE, which together with other proteins from the cag pathogenicity island (PAI), encodes a type IV transporter secretion system. The precise role of CagE is not known, but studies in animal models have shown that it is essential for pathogenesis in Helicobacter pylori induced gastritis and peptic ulceration. Indeed, the expression of the cag PAI has been shown to be essential for stimulating human gastric epithelial cell apoptosis in vitro. Similar type IV transport systems are also found in other bacteria. This family includes the TrbE and VirB proteins from the respective trb and Vir conjugal transfer systems in Agrobacterium tumefaciens. homologs of VirB proteins from other species are also members of this family, e.g. VirB from Brucella suis.
TIGR00929 :Pssm-ID: 454818 [Multi-domain]
Cd Length: 785
Bit Score: 620.11
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 113 KY IPY SS H V D KNIVK TKNG DYVATWQ L M GI N FES I S A E M L ETIDSQVATLVR S FSGLP V SFYN H SC R - ASFY D AFTTKSG 191
Cdd:TIGR00929 10 DF IPY AG H Y D DHVIL TKNG SLMGIIK L E GI S FES A S D E D L NLLHRELNAALK S IGSGQ V ALWV H TV R r KIVI D YPDPEFK 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 192 N KY A DI I SDCYYGSMKKNKFKG N T LY F TL I Y R PD GRVEKLEKR K KSI K EKKDDINIHVKRMN E M I NTFS ------- GA L D 264
Cdd:TIGR00929 90 N GF A AA I DEEWRRKFASSDLYE N D LY L TL E Y K PD SIGVLEKFK K SLT K KTREEFQDNYRETL E S I KALE dikrnll EL L R 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 265 KFTCK LL GM Y EEN G KVF S SQ L S F YNY L LT G KLQ -- KIR V TDSPVYNVLGGVD V F F NH D TGQ I CRIDG N K FF RS I E IK DFC 342
Cdd:TIGR00929 170 EYGAE LL KE Y DKT G HIY S EL L E F LAF L VN G NDI pv TPP V IPGYLDSYIPSSE V L F GK D GFV I RSPKD N R FF SV I S IK EYP 249
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 343 SE T AS G VFDV L QYS D ADY I I THS YTSM SK SE ALS TIK R AE K Q L K S TE D D A VT Q LQ EL EK A KNDIV SGD ISF G YY H FT L M V 422
Cdd:TIGR00929 250 EK T EP G ILNA L LEL D CEF I L THS FSFL SK EA ALS KLG R KR K R L I S KG D R A KS Q IA EL DE A LDELT SGD FVM G EH H LS L V V 329
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 423 M A DSIRE LD ESVSKITADFTDL GI IPALS T MS L P AA YFA QLP AV F HLR PR L S PVSNV NF VE L AS FHNF YQ GK RDK N C W TE 502
Cdd:TIGR00929 330 Y A EDLEK LD AALREARSLLNAC GI VAVIE T LG L E AA FWS QLP GN F SWN PR K S LITSR NF AS L IP FHNF NL GK LRG N P W GP 409
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 503 A VAI LKT P S KQAY Y L N L H NS vlfkdet GE K N L AN T KVI G TA GSGKT MF L SY L ACSL QKY NN petfadsaknkk L T CVFL D 582
Cdd:TIGR00929 410 A LTL LKT Q S GTPF Y F N F H VR ------- DA K V L GH T LIF G PT GSGKT TL L NF L LAQM QKY GG ------------ M T IFAF D 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 583 KDRG A E LC IR ML GG E Y YTV K S GEP T G W NPF A LE A T K RNR I F V K QLMEI L C T RN G ER - L S TRE R LLI S ESV D A V mdfppge 661
Cdd:TIGR00929 471 KDRG M E IF IR AF GG A Y LEI K D GEP F G F NPF Q LE D T E RNR A F L K EWLAM L V T LD G ST d I S AED R NAL S SAI D T V ------- 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 662 M RE YGIT R M L EH L MQRDDR D eq ENGIIL RL SQ W AN G QAH GW V FDN AK D TFNIQHV nn F G I D G TE F LD D P M V CA P ITF YL L 741
Cdd:TIGR00929 544 Y RE GPLI R S L SD L LNFLPK D -- YIDLAD RL EP W LK G GDY GW L FDN PT D DLDLSKI -- T G F D L TE L LD N P K V AT P VLM YL F 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 742 Y RI TQL LDGR RLV I FL DE F W KW L QDEA F SDFVYNK LKT I RK L NG L V IP ATQS PDEI L KNK I SRAVV E V C S T S I Y L A NP D A 821
Cdd:TIGR00929 620 H RI NEA LDGR PFL I II DE A W QY L GNPV F AAKIRDW LKT L RK A NG I V VL ATQS INDA L GSR I ADSIL E Q C A T K I F L P NP E A 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 822 D YN DY V EG L KLT PE EF NIV K NLDPM SR Q FLI kkssl K K G DG ksf S AL A T L D L S G LGG YL KI LS ASAD N L EI FESIYH E - G 900
Cdd:TIGR00929 700 D RE DY A EG F KLT ER EF ELL K STPEE SR K FLI ----- K Q G QS --- S VV A E L N L G G MDN YL RV LS SDTE N V EI IDALIK E y G 771
810
....*....|...
gi 1905476614 901 ME PDDW V P EYLER 913
Cdd:TIGR00929 772 DD PDDW L P IFYRA 784
VirB3
COG3702 Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and ...
1-92
2.96e-22
Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442916
Cd Length: 97
Bit Score: 91.87
E-value: 2.96e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 1 MST L Y K AM TRPAM YV GVP V VP LTVVAGALFLAGVYISK L IW L AI - PVAV FVLR M I TKQ D DHI F N L YF L K L KMLGNSVCN R 79
Cdd:COG3702 2 EDP L F K GL TRPAM FL GVP L VP FVLNVMVSLILFIWTGS L LY L LL a IPLH FVLR L I CRR D PRF F R L LL L R L RTRPRTRNR R 81
90
....*....|...
gi 1905476614 80 F F G ARAFLSGQ Y E 92
Cdd:COG3702 82 F W G GNSYSPLP Y R 94
Name
Accession
Description
Interval
E-value
VirB4_CagE
TIGR00929 type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
113-913
0e+00
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain]
Cd Length: 785
Bit Score: 620.11
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 113 KY IPY SS H V D KNIVK TKNG DYVATWQ L M GI N FES I S A E M L ETIDSQVATLVR S FSGLP V SFYN H SC R - ASFY D AFTTKSG 191
Cdd:TIGR00929 10 DF IPY AG H Y D DHVIL TKNG SLMGIIK L E GI S FES A S D E D L NLLHRELNAALK S IGSGQ V ALWV H TV R r KIVI D YPDPEFK 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 192 N KY A DI I SDCYYGSMKKNKFKG N T LY F TL I Y R PD GRVEKLEKR K KSI K EKKDDINIHVKRMN E M I NTFS ------- GA L D 264
Cdd:TIGR00929 90 N GF A AA I DEEWRRKFASSDLYE N D LY L TL E Y K PD SIGVLEKFK K SLT K KTREEFQDNYRETL E S I KALE dikrnll EL L R 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 265 KFTCK LL GM Y EEN G KVF S SQ L S F YNY L LT G KLQ -- KIR V TDSPVYNVLGGVD V F F NH D TGQ I CRIDG N K FF RS I E IK DFC 342
Cdd:TIGR00929 170 EYGAE LL KE Y DKT G HIY S EL L E F LAF L VN G NDI pv TPP V IPGYLDSYIPSSE V L F GK D GFV I RSPKD N R FF SV I S IK EYP 249
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 343 SE T AS G VFDV L QYS D ADY I I THS YTSM SK SE ALS TIK R AE K Q L K S TE D D A VT Q LQ EL EK A KNDIV SGD ISF G YY H FT L M V 422
Cdd:TIGR00929 250 EK T EP G ILNA L LEL D CEF I L THS FSFL SK EA ALS KLG R KR K R L I S KG D R A KS Q IA EL DE A LDELT SGD FVM G EH H LS L V V 329
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 423 M A DSIRE LD ESVSKITADFTDL GI IPALS T MS L P AA YFA QLP AV F HLR PR L S PVSNV NF VE L AS FHNF YQ GK RDK N C W TE 502
Cdd:TIGR00929 330 Y A EDLEK LD AALREARSLLNAC GI VAVIE T LG L E AA FWS QLP GN F SWN PR K S LITSR NF AS L IP FHNF NL GK LRG N P W GP 409
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 503 A VAI LKT P S KQAY Y L N L H NS vlfkdet GE K N L AN T KVI G TA GSGKT MF L SY L ACSL QKY NN petfadsaknkk L T CVFL D 582
Cdd:TIGR00929 410 A LTL LKT Q S GTPF Y F N F H VR ------- DA K V L GH T LIF G PT GSGKT TL L NF L LAQM QKY GG ------------ M T IFAF D 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 583 KDRG A E LC IR ML GG E Y YTV K S GEP T G W NPF A LE A T K RNR I F V K QLMEI L C T RN G ER - L S TRE R LLI S ESV D A V mdfppge 661
Cdd:TIGR00929 471 KDRG M E IF IR AF GG A Y LEI K D GEP F G F NPF Q LE D T E RNR A F L K EWLAM L V T LD G ST d I S AED R NAL S SAI D T V ------- 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 662 M RE YGIT R M L EH L MQRDDR D eq ENGIIL RL SQ W AN G QAH GW V FDN AK D TFNIQHV nn F G I D G TE F LD D P M V CA P ITF YL L 741
Cdd:TIGR00929 544 Y RE GPLI R S L SD L LNFLPK D -- YIDLAD RL EP W LK G GDY GW L FDN PT D DLDLSKI -- T G F D L TE L LD N P K V AT P VLM YL F 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 742 Y RI TQL LDGR RLV I FL DE F W KW L QDEA F SDFVYNK LKT I RK L NG L V IP ATQS PDEI L KNK I SRAVV E V C S T S I Y L A NP D A 821
Cdd:TIGR00929 620 H RI NEA LDGR PFL I II DE A W QY L GNPV F AAKIRDW LKT L RK A NG I V VL ATQS INDA L GSR I ADSIL E Q C A T K I F L P NP E A 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 822 D YN DY V EG L KLT PE EF NIV K NLDPM SR Q FLI kkssl K K G DG ksf S AL A T L D L S G LGG YL KI LS ASAD N L EI FESIYH E - G 900
Cdd:TIGR00929 700 D RE DY A EG F KLT ER EF ELL K STPEE SR K FLI ----- K Q G QS --- S VV A E L N L G G MDN YL RV LS SDTE N V EI IDALIK E y G 771
810
....*....|...
gi 1905476614 901 ME PDDW V P EYLER 913
Cdd:TIGR00929 772 DD PDDW L P IFYRA 784
VirB4
COG3451 Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ...
329-900
8.97e-146
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain]
Cd Length: 546
Bit Score: 442.85
E-value: 8.97e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 329 G NKFF R SIE IK DFC SET AS G VF D V L QYSDADY I I T H S Y T SMS K S EAL STI KR AEKQ L K S -------- TE DDA VT Q LQEL E 400
Cdd:COG3451 6 G DRYG R VLS IK GYP SET SP G LL D P L LQLPCEF I V T Q S F T PLD K D EAL KKL KR KRRR L E S krkseqal VD DDA ES Q AEDA E 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 401 K A KNDIV SG DISF G YY H F TL M V M AD SIR EL D E S V SKITADFTDL G IIPALS T MSLPA A YFAQ LP AV F HL R P R LSPVSNV N 480
Cdd:COG3451 86 E A LDELQ SG GERL G EV H L TL T V F AD DLE EL E E A V REVESALQSA G FTLVRE T LNQEE A FLSS LP GN F DY R L R RRLLTTS N 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 481 FVE L AS FH N F YQ G KR dkncwt EAVAI L K T P S KQAYYLNL H NS vlfkdetge KNLA NT KVI G TA GSGK TMF L SY L ACS L QK 560
Cdd:COG3451 166 LAA L FP FH S F EL G DP ------ WGIYL L N T R S GTPVFFDF H DG --------- LDNG NT LIL G PS GSGK SFL L KL L LLQ L LR 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 561 Y NN petfadsaknkkl TC V FL D KDRGA E LCI R M LGG E Y YTVKS G E PTG W NPF A LE A T KRN R I F VKQ L M E I L CT R N GE R L S 640
Cdd:COG3451 231 Y GA ------------- RI V IF D PGGSY E ILV R A LGG T Y IDLSP G S PTG L NPF D LE D T EEK R D F LLE L L E L L LG R E GE P L T 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 641 TR ER LL I SES V D A VMDFPPG E M R E y GITRML E H L MQRDD rdeq ENGIIL RL SQWAN G QAH GW V FD N a KDTFNIQHVNNFG 720
Cdd:COG3451 298 PE ER AA I DRA V R A LYRRADP E E R T - TLSDLY E L L KEQPE ---- AKDLAA RL EPYTK G GSY GW L FD G - PTNLDLSDARFVV 371
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 721 I D G TE F LD D P MVCA P ITF YLL Y RI TQL L ---- DGR RLV I FL DE F W KW L QDE AF SD F VYNK LKT I RK L NG L VI P ATQS PDE 796
Cdd:COG3451 372 F D L TE L LD N P ELRP P VLL YLL H RI WNR L rknn DGR PTL I VI DE A W LL L DNP AF AE F LEEW LKT L RK Y NG A VI F ATQS VED 451
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 797 I L KNK I SR A VV E VCS T S I Y L AN P D AD YN DY V E G L K L TPE E FNIVKNLDPMS R Q FLI kkssl K K G D G ksf S ALAT LDLS GL 876
Cdd:COG3451 452 F L SSP I AE A II E NSA T K I L L PQ P K AD IE DY A E L L G L SER E LELIRSAGRGK R D FLI ----- K Q G N G --- S VVFR LDLS PE 523
570 580
....*....|....*....|....
gi 1905476614 877 gg Y L KI LS ASADNLE I FESIYH E G 900
Cdd:COG3451 524 -- E L AL LS TKPEEVA I LDELRA E H 545
PRK13898
PRK13898 type IV secretion system ATPase VirB4; Provisional
101-914
2.64e-112
type IV secretion system ATPase VirB4; Provisional
Pssm-ID: 172418
Cd Length: 800
Bit Score: 363.32
E-value: 2.64e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 101 NAMKLNERIT T GKY IPY SS H VDKNIVK TK NGDYVATWQ L M G IN FE SISA E M L ETIDSQVAT L VR S F S GLPVSF Y N H SC R - 179
Cdd:PRK13898 10 KEKRSKRERH T SHF IPY KC H WNSSTIL TK DNSLLKVIK L S G FA FE TADD E D L DIQKNIRNQ L LK S M S SGSFGL Y F H TI R r 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 180 -- A S F Y D A F - T T K SG N KY A D iisdc Y YGSMKKN K FKG ----- N T LY F T LIYR PD - GR VE K LE KRK K SIKE K KD ------ D 244
Cdd:PRK13898 90 rk A V F S D D F p T V K VP N DF A T ----- Y VNVEWRK K HAT kqsff N E LY I T ILRK PD t KG VE I LE YFL K KLRQ K SN keawen D 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 245 INIHVKRMN EM I N TFSGA L DKFTCK LLG MYEENGK VF SSQ L S F YNYLLT - G KLQ kirvtd S PV YNVL G GV D ------- V F 316
Cdd:PRK13898 165 MKEMYENLE EM T N RVVTS L RNYGPR LLG VRQTPSG VF CEI L E F LSSIVN c G DSP ------ G PV ALPR G TI D eylpthr L F 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 317 F NHD T GQICRIDGN K FFRS I E IK DFCSE T AS G VF D VLQYSDADY IIT H S YTSMSKSE A LSTIKRAEKQLKSTE D D AV T Q L 396
Cdd:PRK13898 239 F GSK T IEAVSHNES K YAGI I S IK EYGPN T SA G ML D GFLQLPYEF IIT Q S FQFTNRQV A IGKMQLQQNRMIQSG D K AV S Q I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 397 Q E LEK A KN D IV SGDI S FG YY H F T LMVMADS I RE L DESV S KITADFTDL G II P ALSTMS L PA A YF AQLP AV F HLRP R LSPV 476
Cdd:PRK13898 319 A E IST A LD D AT SGDI A FG EH H L T ILCIEKN I KA L ENAL S LAEVELSNC G VY P VREKVN L EP A FW AQLP GN F DYIV R KATI 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 477 S NV N FVEL AS F HN FYQ GK RDK N C W T EAV AILK T P S KQAY Y L N L H nsvlfkdetg EKNLAN T KV IG TA G S GKT MFLSY L AC 556
Cdd:PRK13898 399 S TL N MAGF AS Q HN YPL GK KFD N H W G EAV TVFD T T S GTPF Y F N F H ---------- VRDVGH T LI IG PT G A GKT VLMNF L CA 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 557 SLQ K Y n N P ET F adsaknkkltcv F L DKDRGAE LC IR M L G G E Y YTVKSGEPTGW NP FA L EA T KR NR I F VKQLMEI L C T R NG 636
Cdd:PRK13898 469 QAM K F - S P RM F ------------ F F DKDRGAE IF IR A L N G V Y TVIEPRLKCNF NP LQ L DD T SE NR T F LMEWLKV L V T S NG 535
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 637 E R L STRERLL I SES V D avmdfpp G EMREYGIT R M L EH L MQRDDR D e QE N GIIL R LSQ W ANGQA H GWV FDN AK D TFNI Q HV 716
Cdd:PRK13898 536 E S L TAQDIKR I NDA V E ------- G NFKLKKED R R L SN L VAFLGI D - GP N TLAG R IAM W HGKGS H AAI FDN EE D LLDF Q KA 607
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 717 NN FG IDGT E F L D DP MVC AP ITF YL LY RI TQL LDG RRLV I F LDE F W KWLQDEA F SDFVYNK LK TI RKLN GL VI P ATQS PDE 796
Cdd:PRK13898 608 RV FG FEMG E L L K DP VSL AP VLL YL FH RI SIS LDG TPSM I V LDE A W ALIDNPV F APKIKDW LK VL RKLN TF VI F ATQS VED 687
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 797 IL K NK IS RAV V EVCS T S I Y L A N PD A D y ND Y VEGLK L TPE E FNIV K NL DP MS R Q FLIK K sslkkgd G K S f SAL A TLD L S G L 876
Cdd:PRK13898 688 AS K SA IS DTL V QQTA T Q I F L P N LK A T - DI Y RSVFM L SER E YILI K HT DP TT R F FLIK Q ------- G V S - AVV A RIN L D G M 758
810 820 830
....*....|....*....|....*....|....*....
gi 1905476614 877 GGYLKI LS AS A DNLEIFES I YH E - G ME P DD W V P EYL E RA 914
Cdd:PRK13898 759 DDIISV LS GR A ETVLLLDQ I RE E v G DD P NK W L P IFY E AV 797
CagE_TrbE_VirB
pfam03135 CagE, TrbE, VirB family, component of type IV transporter system; This family includes the ...
271-472
4.27e-41
CagE, TrbE, VirB family, component of type IV transporter system; This family includes the Helicobacter pylori protein CagE, which together with other proteins from the cag pathogenicity island (PAI), encodes a type IV transporter secretion system. The precise role of CagE is not known, but studies in animal models have shown that it is essential for pathogenesis in Helicobacter pylori induced gastritis and peptic ulceration. Indeed, the expression of the cag PAI has been shown to be essential for stimulating human gastric epithelial cell apoptosis in vitro. Similar type IV transport systems are also found in other bacteria. This family includes the TrbE and VirB proteins from the respective trb and Vir conjugal transfer systems in Agrobacterium tumefaciens. homologs of VirB proteins from other species are also members of this family, e.g. VirB from Brucella suis.
Pssm-ID: 367350 [Multi-domain]
Cd Length: 202
Bit Score: 149.80
E-value: 4.27e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 271 L GM Y EEN G KVF S SQ L S FYN Y L LT G KLQKI R VTD - SPVYNVL G GVD V F F NH D TGQ I CRIDGN K FFRS I E IK DFCS ET A SG V 349
Cdd:pfam03135 1 L SE Y GKR G VIY S EL L E FYN F L IN G ENHPV R LPR g MYLDEYI G TSR V P F GK D KFI I RTAKDE K YPSI I S IK EYPP ET R SG L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 350 F D VLQYS D ADY IIT H S YTSMS K SE ALS TI K R a EKQLK S TE DDA VT Q LQ ELE K A KNDIV SGD ISF G Y YH FT L MVM A DSIRE 429
Cdd:pfam03135 81 L D KFLDL D EEL IIT Q S FSFKN K QK ALS FL K F - TSRKL S IS DDA KS Q IM ELE D A IDEVR SGD FAL G L YH NS L VLF A EDKEK 159
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1905476614 430 LD E SVS KI T ADFTDL G IIPALS T MSLPA A Y F A QLP AVFH L RP R 472
Cdd:pfam03135 160 LD A SVS EA T SLLNAK G FVAVIE T IGMEP A F F S QLP GNIR L NF R 202
VirB3
COG3702 Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and ...
1-92
2.96e-22
Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442916
Cd Length: 97
Bit Score: 91.87
E-value: 2.96e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 1 MST L Y K AM TRPAM YV GVP V VP LTVVAGALFLAGVYISK L IW L AI - PVAV FVLR M I TKQ D DHI F N L YF L K L KMLGNSVCN R 79
Cdd:COG3702 2 EDP L F K GL TRPAM FL GVP L VP FVLNVMVSLILFIWTGS L LY L LL a IPLH FVLR L I CRR D PRF F R L LL L R L RTRPRTRNR R 81
90
....*....|...
gi 1905476614 80 F F G ARAFLSGQ Y E 92
Cdd:COG3702 82 F W G GNSYSPLP Y R 94
VirB3
pfam05101 Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory ...
2-82
1.22e-16
Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.
Pssm-ID: 428303
Cd Length: 82
Bit Score: 75.35
E-value: 1.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 2 ST L Y KA M TRPAM YV GVP VVPLTVVAGALFLAG - V YI S KLIW L AI P VAVF VLR M I T K Q D DHI F NLYF L K L KMLGNSVCN RF 80
Cdd:pfam05101 1 DP L F KA L TRPAM FL GVP LELFLLNGMVSVILF l V GL S LWYL L LA P PLHL VLR L I A K R D PRM F RVLL L W L QTRPRLRNR RF 80
..
gi 1905476614 81 F G 82
Cdd:pfam05101 81 W G 82
TrwB_TraG_TraD_VirD4
cd01127 TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ...
736-817
2.55e-03
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain]
Cd Length: 144
Bit Score: 39.13
E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 736 IT F YL L YRITQ L LD G --- RR LVIF LDEF W kwlq DEAFSDFVY N K L K T I RK LNGL V IPAT QS PDEILKN --- KISRAVVEV 809
Cdd:cd01127 60 QL F RA L TELAS L SP G rlp RR VWFI LDEF A ---- NLGRIPNLP N L L A T G RK RGIS V VLIL QS LAQLEAV ygk DGAQTILGN 135
....*...
gi 1905476614 810 C S T SI YL A 817
Cdd:cd01127 136 C N T KL YL G 143
PRK13854
PRK13854 type IV secretion system protein VirB3; Provisional
2-82
6.77e-03
type IV secretion system protein VirB3; Provisional
Pssm-ID: 139914
Cd Length: 108
Bit Score: 37.11
E-value: 6.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 2 S TLY K A M TRPA MYV G vpv VPLT VVAGALF LAG --- V YISKLIWLAIPVAV - F VL R MITKQ D DHIFNLYF L K L KML G N SV C 77
Cdd:PRK13854 8 A TLY L A A TRPA LFL G --- VPLT LAGVFMM LAG fvi V IVQNPLYEVVLLPL w F GA R LVVER D YNAASVVL L F L RTA G R SV D 84
....*
gi 1905476614 78 NRFF G 82
Cdd:PRK13854 85 GQAW G 89
Name
Accession
Description
Interval
E-value
VirB4_CagE
TIGR00929 type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found ...
113-913
0e+00
type IV secretion/conjugal transfer ATPase, VirB4 family; Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).
Pssm-ID: 273346 [Multi-domain]
Cd Length: 785
Bit Score: 620.11
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 113 KY IPY SS H V D KNIVK TKNG DYVATWQ L M GI N FES I S A E M L ETIDSQVATLVR S FSGLP V SFYN H SC R - ASFY D AFTTKSG 191
Cdd:TIGR00929 10 DF IPY AG H Y D DHVIL TKNG SLMGIIK L E GI S FES A S D E D L NLLHRELNAALK S IGSGQ V ALWV H TV R r KIVI D YPDPEFK 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 192 N KY A DI I SDCYYGSMKKNKFKG N T LY F TL I Y R PD GRVEKLEKR K KSI K EKKDDINIHVKRMN E M I NTFS ------- GA L D 264
Cdd:TIGR00929 90 N GF A AA I DEEWRRKFASSDLYE N D LY L TL E Y K PD SIGVLEKFK K SLT K KTREEFQDNYRETL E S I KALE dikrnll EL L R 169
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 265 KFTCK LL GM Y EEN G KVF S SQ L S F YNY L LT G KLQ -- KIR V TDSPVYNVLGGVD V F F NH D TGQ I CRIDG N K FF RS I E IK DFC 342
Cdd:TIGR00929 170 EYGAE LL KE Y DKT G HIY S EL L E F LAF L VN G NDI pv TPP V IPGYLDSYIPSSE V L F GK D GFV I RSPKD N R FF SV I S IK EYP 249
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 343 SE T AS G VFDV L QYS D ADY I I THS YTSM SK SE ALS TIK R AE K Q L K S TE D D A VT Q LQ EL EK A KNDIV SGD ISF G YY H FT L M V 422
Cdd:TIGR00929 250 EK T EP G ILNA L LEL D CEF I L THS FSFL SK EA ALS KLG R KR K R L I S KG D R A KS Q IA EL DE A LDELT SGD FVM G EH H LS L V V 329
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 423 M A DSIRE LD ESVSKITADFTDL GI IPALS T MS L P AA YFA QLP AV F HLR PR L S PVSNV NF VE L AS FHNF YQ GK RDK N C W TE 502
Cdd:TIGR00929 330 Y A EDLEK LD AALREARSLLNAC GI VAVIE T LG L E AA FWS QLP GN F SWN PR K S LITSR NF AS L IP FHNF NL GK LRG N P W GP 409
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 503 A VAI LKT P S KQAY Y L N L H NS vlfkdet GE K N L AN T KVI G TA GSGKT MF L SY L ACSL QKY NN petfadsaknkk L T CVFL D 582
Cdd:TIGR00929 410 A LTL LKT Q S GTPF Y F N F H VR ------- DA K V L GH T LIF G PT GSGKT TL L NF L LAQM QKY GG ------------ M T IFAF D 470
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 583 KDRG A E LC IR ML GG E Y YTV K S GEP T G W NPF A LE A T K RNR I F V K QLMEI L C T RN G ER - L S TRE R LLI S ESV D A V mdfppge 661
Cdd:TIGR00929 471 KDRG M E IF IR AF GG A Y LEI K D GEP F G F NPF Q LE D T E RNR A F L K EWLAM L V T LD G ST d I S AED R NAL S SAI D T V ------- 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 662 M RE YGIT R M L EH L MQRDDR D eq ENGIIL RL SQ W AN G QAH GW V FDN AK D TFNIQHV nn F G I D G TE F LD D P M V CA P ITF YL L 741
Cdd:TIGR00929 544 Y RE GPLI R S L SD L LNFLPK D -- YIDLAD RL EP W LK G GDY GW L FDN PT D DLDLSKI -- T G F D L TE L LD N P K V AT P VLM YL F 619
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 742 Y RI TQL LDGR RLV I FL DE F W KW L QDEA F SDFVYNK LKT I RK L NG L V IP ATQS PDEI L KNK I SRAVV E V C S T S I Y L A NP D A 821
Cdd:TIGR00929 620 H RI NEA LDGR PFL I II DE A W QY L GNPV F AAKIRDW LKT L RK A NG I V VL ATQS INDA L GSR I ADSIL E Q C A T K I F L P NP E A 699
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 822 D YN DY V EG L KLT PE EF NIV K NLDPM SR Q FLI kkssl K K G DG ksf S AL A T L D L S G LGG YL KI LS ASAD N L EI FESIYH E - G 900
Cdd:TIGR00929 700 D RE DY A EG F KLT ER EF ELL K STPEE SR K FLI ----- K Q G QS --- S VV A E L N L G G MDN YL RV LS SDTE N V EI IDALIK E y G 771
810
....*....|...
gi 1905476614 901 ME PDDW V P EYLER 913
Cdd:TIGR00929 772 DD PDDW L P IFYRA 784
VirB4
COG3451 Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and ...
329-900
8.97e-146
Type IV secretory pathway, VirB4 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442674 [Multi-domain]
Cd Length: 546
Bit Score: 442.85
E-value: 8.97e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 329 G NKFF R SIE IK DFC SET AS G VF D V L QYSDADY I I T H S Y T SMS K S EAL STI KR AEKQ L K S -------- TE DDA VT Q LQEL E 400
Cdd:COG3451 6 G DRYG R VLS IK GYP SET SP G LL D P L LQLPCEF I V T Q S F T PLD K D EAL KKL KR KRRR L E S krkseqal VD DDA ES Q AEDA E 85
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 401 K A KNDIV SG DISF G YY H F TL M V M AD SIR EL D E S V SKITADFTDL G IIPALS T MSLPA A YFAQ LP AV F HL R P R LSPVSNV N 480
Cdd:COG3451 86 E A LDELQ SG GERL G EV H L TL T V F AD DLE EL E E A V REVESALQSA G FTLVRE T LNQEE A FLSS LP GN F DY R L R RRLLTTS N 165
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 481 FVE L AS FH N F YQ G KR dkncwt EAVAI L K T P S KQAYYLNL H NS vlfkdetge KNLA NT KVI G TA GSGK TMF L SY L ACS L QK 560
Cdd:COG3451 166 LAA L FP FH S F EL G DP ------ WGIYL L N T R S GTPVFFDF H DG --------- LDNG NT LIL G PS GSGK SFL L KL L LLQ L LR 230
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 561 Y NN petfadsaknkkl TC V FL D KDRGA E LCI R M LGG E Y YTVKS G E PTG W NPF A LE A T KRN R I F VKQ L M E I L CT R N GE R L S 640
Cdd:COG3451 231 Y GA ------------- RI V IF D PGGSY E ILV R A LGG T Y IDLSP G S PTG L NPF D LE D T EEK R D F LLE L L E L L LG R E GE P L T 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 641 TR ER LL I SES V D A VMDFPPG E M R E y GITRML E H L MQRDD rdeq ENGIIL RL SQWAN G QAH GW V FD N a KDTFNIQHVNNFG 720
Cdd:COG3451 298 PE ER AA I DRA V R A LYRRADP E E R T - TLSDLY E L L KEQPE ---- AKDLAA RL EPYTK G GSY GW L FD G - PTNLDLSDARFVV 371
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 721 I D G TE F LD D P MVCA P ITF YLL Y RI TQL L ---- DGR RLV I FL DE F W KW L QDE AF SD F VYNK LKT I RK L NG L VI P ATQS PDE 796
Cdd:COG3451 372 F D L TE L LD N P ELRP P VLL YLL H RI WNR L rknn DGR PTL I VI DE A W LL L DNP AF AE F LEEW LKT L RK Y NG A VI F ATQS VED 451
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 797 I L KNK I SR A VV E VCS T S I Y L AN P D AD YN DY V E G L K L TPE E FNIVKNLDPMS R Q FLI kkssl K K G D G ksf S ALAT LDLS GL 876
Cdd:COG3451 452 F L SSP I AE A II E NSA T K I L L PQ P K AD IE DY A E L L G L SER E LELIRSAGRGK R D FLI ----- K Q G N G --- S VVFR LDLS PE 523
570 580
....*....|....*....|....
gi 1905476614 877 gg Y L KI LS ASADNLE I FESIYH E G 900
Cdd:COG3451 524 -- E L AL LS TKPEEVA I LDELRA E H 545
PRK13898
PRK13898 type IV secretion system ATPase VirB4; Provisional
101-914
2.64e-112
type IV secretion system ATPase VirB4; Provisional
Pssm-ID: 172418
Cd Length: 800
Bit Score: 363.32
E-value: 2.64e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 101 NAMKLNERIT T GKY IPY SS H VDKNIVK TK NGDYVATWQ L M G IN FE SISA E M L ETIDSQVAT L VR S F S GLPVSF Y N H SC R - 179
Cdd:PRK13898 10 KEKRSKRERH T SHF IPY KC H WNSSTIL TK DNSLLKVIK L S G FA FE TADD E D L DIQKNIRNQ L LK S M S SGSFGL Y F H TI R r 89
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 180 -- A S F Y D A F - T T K SG N KY A D iisdc Y YGSMKKN K FKG ----- N T LY F T LIYR PD - GR VE K LE KRK K SIKE K KD ------ D 244
Cdd:PRK13898 90 rk A V F S D D F p T V K VP N DF A T ----- Y VNVEWRK K HAT kqsff N E LY I T ILRK PD t KG VE I LE YFL K KLRQ K SN keawen D 164
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 245 INIHVKRMN EM I N TFSGA L DKFTCK LLG MYEENGK VF SSQ L S F YNYLLT - G KLQ kirvtd S PV YNVL G GV D ------- V F 316
Cdd:PRK13898 165 MKEMYENLE EM T N RVVTS L RNYGPR LLG VRQTPSG VF CEI L E F LSSIVN c G DSP ------ G PV ALPR G TI D eylpthr L F 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 317 F NHD T GQICRIDGN K FFRS I E IK DFCSE T AS G VF D VLQYSDADY IIT H S YTSMSKSE A LSTIKRAEKQLKSTE D D AV T Q L 396
Cdd:PRK13898 239 F GSK T IEAVSHNES K YAGI I S IK EYGPN T SA G ML D GFLQLPYEF IIT Q S FQFTNRQV A IGKMQLQQNRMIQSG D K AV S Q I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 397 Q E LEK A KN D IV SGDI S FG YY H F T LMVMADS I RE L DESV S KITADFTDL G II P ALSTMS L PA A YF AQLP AV F HLRP R LSPV 476
Cdd:PRK13898 319 A E IST A LD D AT SGDI A FG EH H L T ILCIEKN I KA L ENAL S LAEVELSNC G VY P VREKVN L EP A FW AQLP GN F DYIV R KATI 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 477 S NV N FVEL AS F HN FYQ GK RDK N C W T EAV AILK T P S KQAY Y L N L H nsvlfkdetg EKNLAN T KV IG TA G S GKT MFLSY L AC 556
Cdd:PRK13898 399 S TL N MAGF AS Q HN YPL GK KFD N H W G EAV TVFD T T S GTPF Y F N F H ---------- VRDVGH T LI IG PT G A GKT VLMNF L CA 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 557 SLQ K Y n N P ET F adsaknkkltcv F L DKDRGAE LC IR M L G G E Y YTVKSGEPTGW NP FA L EA T KR NR I F VKQLMEI L C T R NG 636
Cdd:PRK13898 469 QAM K F - S P RM F ------------ F F DKDRGAE IF IR A L N G V Y TVIEPRLKCNF NP LQ L DD T SE NR T F LMEWLKV L V T S NG 535
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 637 E R L STRERLL I SES V D avmdfpp G EMREYGIT R M L EH L MQRDDR D e QE N GIIL R LSQ W ANGQA H GWV FDN AK D TFNI Q HV 716
Cdd:PRK13898 536 E S L TAQDIKR I NDA V E ------- G NFKLKKED R R L SN L VAFLGI D - GP N TLAG R IAM W HGKGS H AAI FDN EE D LLDF Q KA 607
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 717 NN FG IDGT E F L D DP MVC AP ITF YL LY RI TQL LDG RRLV I F LDE F W KWLQDEA F SDFVYNK LK TI RKLN GL VI P ATQS PDE 796
Cdd:PRK13898 608 RV FG FEMG E L L K DP VSL AP VLL YL FH RI SIS LDG TPSM I V LDE A W ALIDNPV F APKIKDW LK VL RKLN TF VI F ATQS VED 687
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 797 IL K NK IS RAV V EVCS T S I Y L A N PD A D y ND Y VEGLK L TPE E FNIV K NL DP MS R Q FLIK K sslkkgd G K S f SAL A TLD L S G L 876
Cdd:PRK13898 688 AS K SA IS DTL V QQTA T Q I F L P N LK A T - DI Y RSVFM L SER E YILI K HT DP TT R F FLIK Q ------- G V S - AVV A RIN L D G M 758
810 820 830
....*....|....*....|....*....|....*....
gi 1905476614 877 GGYLKI LS AS A DNLEIFES I YH E - G ME P DD W V P EYL E RA 914
Cdd:PRK13898 759 DDIISV LS GR A ETVLLLDQ I RE E v G DD P NK W L P IFY E AV 797
PRK13853
PRK13853 type IV secretion system protein VirB4; Provisional
114-913
2.16e-103
type IV secretion system protein VirB4; Provisional
Pssm-ID: 139913 [Multi-domain]
Cd Length: 789
Bit Score: 339.53
E-value: 2.16e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 114 Y I PY SS H VDKN IV KTKN G DYVATWQLM G IN FE SISA EM LETIDSQVA TL V R SFSGLP VS F Y N H SC R AS fy D AFTTKSG -- 191
Cdd:PRK13853 15 Y L PY VG H LSDH IV LLED G SIMTMAHIS G LP FE LEEV EM RNARCRAFN TL L R NIADDN VS I Y A H LV R HN -- D VPPPPAR hf 92
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 192 - NKY A DII S DCYYGSMKKN K FKG N TLYF TLI YR P DGRVE K LEK R KKSIKE KK D - D INIHVKRMNEMINTFS GALD KFTCK 269
Cdd:PRK13853 93 r SAF A ASL S EAFEERVLSG K LLR N DHFL TLI VS P RTALG K VKR R FTKRYG KK E n D LAGQIRNLEDLWHVVA GALD AYGLR 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 270 L LG MY E ENGKV F SSQLSFYNYLL TG KLQKIR V TDSPVYNVLGGVD V FFNHDTGQ I c R IDGNKFFR SI - EIKDFCSE T AS G 348
Cdd:PRK13853 173 R LG IR E KQQVL F TEIGEALRLIM TG RFTPVP V VSGSLGASIYTDR V ICGKRGLE I - R TPKDSYVG SI f SFREYPAK T RP G 251
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 349 VFDV L QYS D ADYII T H S YTSMSKSE A LSTIKRAEK Q LK S TE D D AVTQ LQ EL EK A KNDIV S GDISF G YY H FT L M V M AD SIR 428
Cdd:PRK13853 252 MLNT L LSL D FPLVL T Q S FSFLTRAQ A HAKLSLKSS Q MT S SG D K AVTQ IS EL AE A EDALA S NEFVM G SH H LS L C V Y AD DLN 331
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 429 E L DESVSKITADFT D L G IIPALSTMSLP AAY FA QLP AVFHL R P R LSPVSNV NF VE L A SF H NF YQ G K R DKN c W TE A V A ILK 508
Cdd:PRK13853 332 S L ADRGARARTRLA D A G AVVVQEGIGME AAY WS QLP GNHKW R T R PGAITSR NF AG L V SF E NF PE G A R SGH - W GN A I A RFR 410
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 509 T PSKQAYYLNL H nsvlfkdetg E KNLAN T KVI G TA G S GKT MFLSYLACS L qkynn PETFA D S A K nkkl TC VF L DKDRG A E 588
Cdd:PRK13853 411 T NGGTPFDYIP H ---------- E HDVGM T AIF G PI G R GKT TLMTFILAM L ----- EQSMV D R A G ---- AV VF F DKDRG G E 471
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 589 L CI R ML GG E Y YTVKS G E P T G WN P F - A LE A T KRN R I F VKQLMEI L CTRN G E - RL S TR E RLLISESVDAVMD F P P g E MR E yg 666
Cdd:PRK13853 472 L LV R AT GG T Y LALRR G V P S G LA P L r G LE N T AAS R D F LREWIVA L IESD G R g GI S PE E NRRLVRGIQRQLS F D P - N MR S -- 548
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 667 ITRML E H L MQRD drdeq EN G IIL RL SQ W AN G Q A H GW V FD NAK D TFNI q HVNNF G I D G T EF L DDPM VCAP ITF YLL Y RI TQ 746
Cdd:PRK13853 549 LAGLR E F L LHGP ----- AE G AGA RL QR W CR G N A L GW A FD GEV D EVKL - DPSIT G F D M T HL L EYEE VCAP AAA YLL H RI GA 622
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 747 LL DGRR L V IFL DEF WKW L QDEA F SDF V YNK L K T I RK L NG LV I P ATQ S P DEI L KNKISRAV V EV C S T S I YLAN P D AD YND Y 826
Cdd:PRK13853 623 MV DGRR F V MSC DEF RAY L LNPK F AAV V DKF L L T V RK N NG ML I L ATQ Q P EHV L ESPLGASL V AQ C M T K I FYPS P T AD RSA Y 702
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 827 VE GLK L T PE EF N - I VKNLDPM SR Q FL I K K sslkkgdg K S F S ALATL DL SGLGG Y LKI LS AS A DNLEIFESIYH - E G ME P D 904
Cdd:PRK13853 703 ID GLK C T EK EF Q a I REDMAVG SR K FL L K R -------- E S G S VICEF DL RDMRE Y VAV LS GR A NTVRFADQLRE t H G DD P S 774
....*....
gi 1905476614 905 D W VP E YLE R 913
Cdd:PRK13853 775 A W LS E FMA R 783
CagE_TrbE_VirB
pfam03135 CagE, TrbE, VirB family, component of type IV transporter system; This family includes the ...
271-472
4.27e-41
CagE, TrbE, VirB family, component of type IV transporter system; This family includes the Helicobacter pylori protein CagE, which together with other proteins from the cag pathogenicity island (PAI), encodes a type IV transporter secretion system. The precise role of CagE is not known, but studies in animal models have shown that it is essential for pathogenesis in Helicobacter pylori induced gastritis and peptic ulceration. Indeed, the expression of the cag PAI has been shown to be essential for stimulating human gastric epithelial cell apoptosis in vitro. Similar type IV transport systems are also found in other bacteria. This family includes the TrbE and VirB proteins from the respective trb and Vir conjugal transfer systems in Agrobacterium tumefaciens. homologs of VirB proteins from other species are also members of this family, e.g. VirB from Brucella suis.
Pssm-ID: 367350 [Multi-domain]
Cd Length: 202
Bit Score: 149.80
E-value: 4.27e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 271 L GM Y EEN G KVF S SQ L S FYN Y L LT G KLQKI R VTD - SPVYNVL G GVD V F F NH D TGQ I CRIDGN K FFRS I E IK DFCS ET A SG V 349
Cdd:pfam03135 1 L SE Y GKR G VIY S EL L E FYN F L IN G ENHPV R LPR g MYLDEYI G TSR V P F GK D KFI I RTAKDE K YPSI I S IK EYPP ET R SG L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 350 F D VLQYS D ADY IIT H S YTSMS K SE ALS TI K R a EKQLK S TE DDA VT Q LQ ELE K A KNDIV SGD ISF G Y YH FT L MVM A DSIRE 429
Cdd:pfam03135 81 L D KFLDL D EEL IIT Q S FSFKN K QK ALS FL K F - TSRKL S IS DDA KS Q IM ELE D A IDEVR SGD FAL G L YH NS L VLF A EDKEK 159
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 1905476614 430 LD E SVS KI T ADFTDL G IIPALS T MSLPA A Y F A QLP AVFH L RP R 472
Cdd:pfam03135 160 LD A SVS EA T SLLNAK G FVAVIE T IGMEP A F F S QLP GNIR L NF R 202
PRK13891
PRK13891 conjugal transfer protein TrbE; Provisional
275-821
2.00e-28
conjugal transfer protein TrbE; Provisional
Pssm-ID: 184375 [Multi-domain]
Cd Length: 852
Bit Score: 122.94
E-value: 2.00e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 275 E ENGK V FSSQ - LS FYNYLL TG KLQKIRVTDS P V Y -- NVL GG VDVF fnhd T G QICR I d G N KF FRSIE I KD F CS E TAS G VFD 351
Cdd:PRK13891 220 E DGRE V THDD f LS WLQFCV TG LNHPVMLPSN P M Y ld ALI GG QELW ---- G G VVPK I - G R KF IQVVA I EG F PL E SYP G ILS 294
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 352 V L QYSDAD Y IITHSYTS M SKS EA LSTIKRAE K QL K ---------------- S TED DA VTQLQEL E K A KNDIV SG DISF GY 415
Cdd:PRK13891 295 A L AELPIE Y RWSSRFIF M DQH EA VKHLDKFR K KW K qkirgffdqvfntntg S IDQ DA LSMVGDA E A A IAEVN SG LVAQ GY 374
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 416 Y HFTLMV M ADSIRE L DE S VSKITADFTD LG IIPALS T MSLPA AY FAQ LP A -- V FHL R PR L sp VSNV N FVE L ASFHNFYQ G 493
Cdd:PRK13891 375 Y TSVVVL M DEDRER L EA S ALLVEKAINR LG FAARIE T INTMD AY LGS LP G hg V ENV R RP L -- INTM N LAD L LPTSSIWT G 452
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 494 KRDKN C ----- WTE A VAILK T PSKQAYY LNLH nsvlfkdetg EKN L AN T KVI G TA G S GK TMF L SYL A CS L QK Y NNPETF A 568
Cdd:PRK13891 453 SATAP C pmypp LSP A LMHCV T VGATPFR LNLH ---------- VRD L GH T FMF G PT G A GK STH L GII A AQ L RR Y AGMSIY A 522
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 569 dsaknkkltcvf L DK DR ------- G AELCIRMLG G EYY TV KSGEPT - GWN P FALEA TK RN R IFVKQLMEILCTR NG ERLS 640
Cdd:PRK13891 523 ------------ F DK GM smyplaa G IRAATKGKS G LHF TV AADDDR l AFC P LQFLE TK GD R AWAMEWIDTILAL NG VNTT 590
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 641 TRE R LL I --------------- SE SVDAVM D FPPG E - MRE Y GITRMLE HL M qrddr D EQ E N G ii L R LS QWA ngqahgwvf 704
Cdd:PRK13891 591 PAQ R NE I gnaimsmhasgartl SE FSVTIQ D EAIR E a IKQ Y TVDGSMG HL L ----- D AE E D G -- L S LS DFT --------- 654
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 705 dnakd T F N I QHVN N F G idg TE F lddpmv CA P ITF YL LY RI TQL L D G RRL VI F LDE F W KW L QDE AF SDFVYNK LK TI RK L N 784
Cdd:PRK13891 655 ----- V F E I EELM N L G --- EK F ------ AL P VLL YL FR RI ERA L K G QPA VI I LDE A W LM L GHP AF RAKIREW LK VL RK A N 720
570 580 590
....*....|....*....|....*....|....*..
gi 1905476614 785 G LV IP ATQS PDEILKNK I SRAV VE VCS T S I Y L A N PD A 821
Cdd:PRK13891 721 C LV LM ATQS LSDAANSG I LDVI VE STA T K I F L P N VY A 757
PRK13830
PRK13830 conjugal transfer protein TrbE; Provisional
285-845
3.01e-27
conjugal transfer protein TrbE; Provisional
Pssm-ID: 237525 [Multi-domain]
Cd Length: 818
Bit Score: 119.18
E-value: 3.01e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 285 LS F YNYLL TG KLQKI R VT D S P V Y - NV L gg V DVFFN H dt G QICRID g N K F FRSIE I KDFCS E TAS G VFDV L QYSDAD Y IIT 363
Cdd:PRK13830 201 FQ F IRFCI TG ENHPV R LP D I P M Y l DW L -- V TAELQ H -- G LTPKVE - N R F LGVVA I DGLPA E SWP G ILNS L DLMPLT Y RWS 275
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 364 HSYTSMSKS EA LSTIK R AE K ---------------- Q LK S TED DA VTQLQ E L E K A KNDIV S GDISF GYY HFTLMVMADSI 427
Cdd:PRK13830 276 SRFIFLDAE EA RQKLE R TR K kwqqkvrpffdqlfqt Q SR S VDQ DA MMMVA E T E D A IAQAS S QLVAY GYY TPVIVLFDEDQ 355
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 428 RE L D E SVSK I TADFTDL G IIPALS T MSLPA A YFAQ LP AVFHLRP R LSPVSNV N FVE L ASFHNFYQ G KRDKN C -- WTEA -- 503
Cdd:PRK13830 356 ER L Q E KAEA I RRLIQAE G FGARIE T LNATD A FLGS LP GNWYANI R EPLINTR N LAD L IPLNSVWS G SPVAP C pf YPPN sp 435
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 504 ---- VA ILK TP skqa YY LNLH nsvlf K D ET G eknla N T KVI G TA GSGK TMF L SYL A CSLQK Y NNPET FA dsaknkkltcv 579
Cdd:PRK13830 436 plmq VA SGS TP ---- FR LNLH ----- V D DV G ----- H T LIF G PT GSGK STL L ALI A AQFRR Y AGAQI FA ----------- 490
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 580 f L DK D R GAELCIRML GG EY Y TVKSGEPTGWN ----- P F A LEA T KRN R IFVKQLM E I L CTRN G ERLSTRE R LL IS ESVD -- 652
Cdd:PRK13830 491 - F DK G R SMLPLTLAA GG DH Y EIGGDAAEEGE glafc P L A ELS T DGD R AWAAEWI E T L VALQ G VTITPDH R NA IS RQIG lm 569
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 653 ------ AVM DF PP G - E MRE ------- Y GITRMLEH L M qrddr D EQ E N G II L RLS Q wangqahgwvfdnakd TF N I QHVN N 718
Cdd:PRK13830 570 aeargr SLS DF VS G v Q MRE ikdalhh Y TVDGPMGQ L L ----- D AE E D G LA L GAF Q ---------------- TF E I EELM N 628
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 719 F G idgtefl DDPM V ca P ITF YL LY RI TQL L D G RRLV I F LDE F W KW L QDEA F S D FVYNK LK TI RK L N GL V IP ATQS PDEIL 798
Cdd:PRK13830 629 M G ------- ERNL V -- P VLT YL FR RI EKR L T G APSL I I LDE A W LM L GHPV F R D KIREW LK VL RK A N CA V VL ATQS ISDAE 699
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 1905476614 799 KNK I SRAVV E V C S T S I Y L A N PD A --- DYNDYV E GLKLTPEEFN IV KNLD P 845
Cdd:PRK13830 700 RSG I IDVLK E S C P T K I C L P N GA A rep GTREFY E RIGFNERQIE IV ATAI P 749
PRK13873
PRK13873 conjugal transfer ATPase TrbE; Provisional
329-821
2.34e-22
conjugal transfer ATPase TrbE; Provisional
Pssm-ID: 237536 [Multi-domain]
Cd Length: 811
Bit Score: 103.45
E-value: 2.34e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 329 G NKFF R SIE I KD F CSE T AS G VF D V L QYSDAD Y IITHSYTSMS K SE A LSTIKRAEK Q ----------- LK ST -------- E 389
Cdd:PRK13873 225 G DAHL R VLT I RG F PTA T WP G IL D D L NRLAFP Y RWSTRAICLD K TD A TKLLTKIRR Q wfakrksvaai LK EV mtneasal V 304
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 390 D -------- DA VTQ LQEL E kakndiv SGDIS FGY YHF T LM V MADSIREL DE --- S V S K IT -- AD FT dlg I IP al S T MSLP 456
Cdd:PRK13873 305 D tdaankaa DA DAA LQEL G ------- ADQVG FGY VTA T VT V WDADPAIA DE klr L V E K VI qg RG FT --- C IP -- E T LNAV 372
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 457 A A YFAQ LP AVFHLRP R LS PVS NV N FVELASFHNFYQ G - K R DKNCWTEAVAILK T PSKQAYY L N LH NS vlfkdetgek NLA 535
Cdd:PRK13873 373 E A WLGS LP GHVYANV R QP PVS TL N LAHMMPLSAVWA G p E R NEHLDAPPLLYAR T EGSTPFR L S LH VG ---------- DVG 442
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 536 N T K V I G TA G S GK TMF L SYL A CSLQK Y NNPET FA dsaknkkltcvf L D KDRGAELCIRML GG EYYTV -- KSGEPTGWN P F A 613
Cdd:PRK13873 443 H T L V V G PT G A GK SVL L ALM A LQFRR Y PGAQV FA ------------ F D FGGSIRAATLAM GG DWHDL gg GADGSVALQ P L A 510
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 614 LEATKRN R IFVKQLMEILCT R N G ERLSTRERLL I SESVDAVMDF P PG E MREY G ITRM L ehlmqrddrde Q E N GIILR L SQ 693
Cdd:PRK13873 511 RIDDEAE R AWAAEWIAGILA R E G VAVTPEVKEH I WSALTSLASA P VE E RTLT G LSVL L ----------- Q S N ALKQA L AP 579
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 694 WAN G QA HG WVF D NAKDTFNIQH V NN F GID G te FLDDPMVCAPITF YL LY RI TQLL DGR RLVIF LDE F W KW L Q D EA F SDFV 773
Cdd:PRK13873 580 YCL G GP HG RLL D ADAERLGSAD V QA F EME G -- LMGTKAAAPAVLS YL FH RI EDRF DGR PTLLI LDE A W LF L D D PV F AAQL 657
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 1905476614 774 YNK LKT I RK L N GL VI P ATQS PDE I LKNK I SR A VV E V C S T S I Y L A N PD A 821
Cdd:PRK13873 658 REW LKT L RK K N VS VI F ATQS LAD I DGSA I AP A II E S C P T R I F L P N ER A 705
VirB3
COG3702 Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and ...
1-92
2.96e-22
Type IV secretory pathway, VirB3 component [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442916
Cd Length: 97
Bit Score: 91.87
E-value: 2.96e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 1 MST L Y K AM TRPAM YV GVP V VP LTVVAGALFLAGVYISK L IW L AI - PVAV FVLR M I TKQ D DHI F N L YF L K L KMLGNSVCN R 79
Cdd:COG3702 2 EDP L F K GL TRPAM FL GVP L VP FVLNVMVSLILFIWTGS L LY L LL a IPLH FVLR L I CRR D PRF F R L LL L R L RTRPRTRNR R 81
90
....*....|...
gi 1905476614 80 F F G ARAFLSGQ Y E 92
Cdd:COG3702 82 F W G GNSYSPLP Y R 94
VirB3
pfam05101 Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory ...
2-82
1.22e-16
Type IV secretory pathway, VirB3-like protein; This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.
Pssm-ID: 428303
Cd Length: 82
Bit Score: 75.35
E-value: 1.22e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 2 ST L Y KA M TRPAM YV GVP VVPLTVVAGALFLAG - V YI S KLIW L AI P VAVF VLR M I T K Q D DHI F NLYF L K L KMLGNSVCN RF 80
Cdd:pfam05101 1 DP L F KA L TRPAM FL GVP LELFLLNGMVSVILF l V GL S LWYL L LA P PLHL VLR L I A K R D PRM F RVLL L W L QTRPRLRNR RF 80
..
gi 1905476614 81 F G 82
Cdd:pfam05101 81 W G 82
VirD4
COG3505 Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ...
539-827
6.94e-06
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain]
Cd Length: 402
Bit Score: 49.60
E-value: 6.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 539 VIG TA GSGKT MF L SYLACSLQKYNNP etfadsaknkklt C V FL D - K DRG AEL CIRML --- G GEY Y TV --- KSGEPTG WNP 611
Cdd:COG3505 4 VIG PT GSGKT VG L VIPNLTQLARGES ------------- V V VT D p K GDL AEL TAGFR rra G YDV Y VF dpf DPERSHR WNP 70
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 612 FALEATKRN rif VKQ L M E I L CTRN G ERLST ------ RE R L L ISESVD A VM --- DFPPGEMREY ------ GITRM LE H L MQ 676
Cdd:COG3505 71 LDEIRDPAD --- AQE L A E A L IPAL G GGGGG dpfwre AA R A L LAALIL A LA eeg RRTLADVYRL lsepee ELREL LE A L PE 147
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 677 RDDR ------------- DEQENGII ---- LR L SQWANGQAHGWV fdn AKDT F NI qhvnnfgidg TEFLDDPM --- VCA P I 736
Cdd:COG3505 148 SPHP pvadtlaaflnaa EKTRSSVL stla SA L ELLSDPEVAALT --- SGSD F DL ---------- RDLIREKG tly LVL P P 214
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 737 ---- T FYL L Y R -- IT QL LDG ------------ R RLVIF LDEF --- WKW lqdeafs DFVYNK L K T I R KLNGLVIPAT QS P - 794
Cdd:COG3505 215 ddls T LAP L L R ll LS QL IRA llrraersgrlp R PVLLL LDEF anl GRL ------- PSLETL L A T G R GYGIRLVLIL QS L a 287
330 340 350
....*....|....*....|....*....|....*
gi 1905476614 795 -- DE I LKNKISRAVVEV C S T S I Y L ANP D ADYND Y V 827
Cdd:COG3505 288 ql EA I YGEEGAETILGN C G T K I F L GVN D PETAE Y L 322
TrwB_TraG_TraD_VirD4
cd01127 TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ...
736-817
2.55e-03
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain]
Cd Length: 144
Bit Score: 39.13
E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 736 IT F YL L YRITQ L LD G --- RR LVIF LDEF W kwlq DEAFSDFVY N K L K T I RK LNGL V IPAT QS PDEILKN --- KISRAVVEV 809
Cdd:cd01127 60 QL F RA L TELAS L SP G rlp RR VWFI LDEF A ---- NLGRIPNLP N L L A T G RK RGIS V VLIL QS LAQLEAV ygk DGAQTILGN 135
....*...
gi 1905476614 810 C S T SI YL A 817
Cdd:cd01127 136 C N T KL YL G 143
PRK13854
PRK13854 type IV secretion system protein VirB3; Provisional
2-82
6.77e-03
type IV secretion system protein VirB3; Provisional
Pssm-ID: 139914
Cd Length: 108
Bit Score: 37.11
E-value: 6.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1905476614 2 S TLY K A M TRPA MYV G vpv VPLT VVAGALF LAG --- V YISKLIWLAIPVAV - F VL R MITKQ D DHIFNLYF L K L KML G N SV C 77
Cdd:PRK13854 8 A TLY L A A TRPA LFL G --- VPLT LAGVFMM LAG fvi V IVQNPLYEVVLLPL w F GA R LVVER D YNAASVVL L F L RTA G R SV D 84
....*
gi 1905476614 78 NRFF G 82
Cdd:PRK13854 85 GQAW G 89
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
