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Conserved domains on  [gi|1942250095|gb|QPP20632|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Phalanger sp. AMS M16263]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-315 3.48e-142

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 405.77  E-value: 3.48e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00105   13 LFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00105   93 TASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00105  173 TQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLG 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQWPHPQTKTTNIIP 315
Cdd:MTH00105  253 GLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTKPMTLLP 327
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-315 3.48e-142

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 405.77  E-value: 3.48e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00105   13 LFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00105   93 TASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00105  173 TQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLG 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQWPHPQTKTTNIIP 315
Cdd:MTH00105  253 GLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTKPMTLLP 327
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 11-256 7.55e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.23  E-value: 7.55e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  11 SSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQTSSTI---- 85
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  86 -------MTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILL-TWQKIAP-----TSLMYQISPSLNMKMLIILALLSTIM 152
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 153 GGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPT---------LTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWN 223
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIygiqaaifhLLTHGLFSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1942250095 224 KSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQ 256
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 2-286 5.08e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 87.48  E-value: 5.08e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   2 LLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYP-NHPRATESAIKYFLTQSTASMMLMFAIinnAWM---TNQWTLSQI 77
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAFRrDDRRSSEAALKYFLLGALSSGFLLYGI---SLLygaTGSLNLAGI 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  78 S-----NQTSSTIMTLALAM-------KLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTS----LMYQISPSLNM-- 139
Cdd:COG1007   189 AaalaaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPGLAAdw 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 140 -KMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTL------------TLLNLTIYITTTLTLFLA 206
Cdd:COG1007   269 qLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaalfyllayLFMNLGAFAVILLLSRKG 348

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 207 LNHSSITkmkSLANLWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIY 286
Cdd:COG1007   349 GEAEEIE---DLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 2-285 8.51e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.98  E-value: 8.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   2 LLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLkRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSST------------IMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSL-------NMKM 141
Cdd:TIGR01770 192 LSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 142 LIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTLLN----------LTIYITTTLTLFLALNHSS 211
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlfyifiyalMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1942250095 212 ITKMKSLANLWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRII 285
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-315 3.48e-142

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 405.77  E-value: 3.48e-142
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00105   13 LFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSGQWTITKLTNP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00105   93 TASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAILSILIGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00105  173 TQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLG 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQWPHPQTKTTNIIP 315
Cdd:MTH00105  253 GLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENTKPMTLLP 327
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-311 1.09e-113

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 333.31  E-value: 1.09e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00135   13 LGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMSHP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSlNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00135   93 LPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLTSTLVGGWGGLNQ 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00135  172 TQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLG 251

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQWPHPQTKTT 311
Cdd:MTH00135  252 GLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLT 322
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-313 1.08e-104

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 310.22  E-value: 1.08e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00112   13 LILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQWDITQLTNP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00112   93 TSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAILSTLIGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00112  173 TQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLA 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQWPHPQTKTTNI 313
Cdd:MTH00112  253 GLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLT 325
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-315 7.13e-102

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 303.00  E-value: 7.13e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00070   13 LALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTIMNMQTP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00070   93 LPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00070  173 TQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLG 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQWPHPqTKTTNIIP 315
Cdd:MTH00070  253 GLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-NKTNNLLS 326
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-303 2.14e-80

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 248.34  E-value: 2.14e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00200   13 LGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWGISEMLGP 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00200   93 LSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLLSVLVGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00200  173 TQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLG 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQW 303
Cdd:MTH00200  253 GLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-294 1.66e-74

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 233.28  E-value: 1.66e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:MTH00041   13 IILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGPLNT 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00041   93 LSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQ 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00041  173 TQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLG 252

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPP 294
Cdd:MTH00041  253 GLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFP 306
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-303 2.55e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 172.76  E-value: 2.55e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTlsqisnq 80
Cdd:MTH00144   13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF------- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 tSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNM-KMLIILALLSTIMGGWGGLN 159
Cdd:MTH00144   86 -SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIGGLN 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 160 QTHMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLwNKSTPMTIVIALMLLSL 239
Cdd:MTH00144  165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSL 243

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1942250095 240 GGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSKLQW 303
Cdd:MTH00144  244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-300 8.06e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 163.84  E-value: 8.06e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNqwtlsqISNQ 80
Cdd:MTH00160   14 LIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM------LFNN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQIspsLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00160   88 ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIILSAIIGAIGGLNQ 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00160  165 TSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLG 244

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSK 300
Cdd:MTH00160  245 GLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNL 304
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-293 1.61e-40

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 144.54  E-value: 1.61e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAiinnawMTNQWTLSQISNQ 80
Cdd:MTH00011   15 MTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLG------MTMMWSFPSLLKN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILALLSTIMGGWGGLNQ 160
Cdd:MTH00011   89 ITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQ 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSLG 240
Cdd:MTH00011  169 TQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLG 248

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1942250095 241 GLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMP 293
Cdd:MTH00011  249 GLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLSP 301
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 1-288 1.55e-34

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 128.64  E-value: 1.55e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMfaiinnawMTNQWTLSQISNQ 80
Cdd:MTH00197    7 IFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLL--------MGGSLSFSNLYLS 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSSTIMT-LALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPtsLMYQISPSLNMKMLIILALLSTIMGGWGGLN 159
Cdd:MTH00197   79 LLSVVLViLGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGMN 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 160 QTHMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWNKSTPMTIVIALMLLSL 239
Cdd:MTH00197  157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 1942250095 240 GGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTT 288
Cdd:MTH00197  237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 1-285 7.92e-24

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 100.10  E-value: 7.92e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAI-IPMMTYPNHPRATESAIKYFLTQSTASMMLMFAI-------------INNA 66
Cdd:MTH00196    2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCallcgttgglhlsYINL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  67 WMTNQWTLSQISNQTSSTIMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNmkMLIILA 146
Cdd:MTH00196   82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 147 LLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTI------IILINPTLTLLNLTIYITTTLTLFLALNHSSITKMKSLAN 220
Cdd:MTH00196  160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWgieigsFESIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFSG 239

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1942250095 221 LWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRII 285
Cdd:MTH00196  240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 11-256 7.55e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.23  E-value: 7.55e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  11 SSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQTSSTI---- 85
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYwGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGLnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  86 -------MTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILL-TWQKIAP-----TSLMYQISPSLNMKMLIILALLSTIM 152
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 153 GGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPT---------LTLLNLTIYITTTLTLFLALNHSSITKMKSLANLWN 223
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTIygiqaaifhLLTHGLFSAGLFLCAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1942250095 224 KSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQ 256
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILA 273
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 1-185 1.92e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 88.54  E-value: 1.92e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAI-IPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISN 79
Cdd:MTH00199  106 VALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  80 QTSSTI----MTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMkmLIILALLSTIMGGW 155
Cdd:MTH00199  186 ILTGDVgkilITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNV--VLICAVLSIIYGAI 263

                         170       180       190
                  ....*....|....*....|....*....|
gi 1942250095 156 GGLNQTHMRKILAYSSIAHMGWMTIIILIN 185
Cdd:MTH00199  264 GALNQTKIKRLLAYSGIGHMGFILFGVAIG 293
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 2-286 5.08e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 87.48  E-value: 5.08e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   2 LLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYP-NHPRATESAIKYFLTQSTASMMLMFAIinnAWM---TNQWTLSQI 77
Cdd:COG1007   112 TLGMMLMASANDLLTLFLGLELLSLSLYVLVAFRrDDRRSSEAALKYFLLGALSSGFLLYGI---SLLygaTGSLNLAGI 188

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  78 S-----NQTSSTIMTLALAM-------KLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTS----LMYQISPSLNM-- 139
Cdd:COG1007   189 AaalaaGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAallrLLVEAFPGLAAdw 268

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 140 -KMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTL------------TLLNLTIYITTTLTLFLA 206
Cdd:COG1007   269 qLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaalfyllayLFMNLGAFAVILLLSRKG 348

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 207 LNHSSITkmkSLANLWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIY 286
Cdd:COG1007   349 GEAEEIE---DLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
2-285 2.03e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 82.56  E-value: 2.03e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   2 LLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPN-HPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQI--- 77
Cdd:PRK05777  113 LLGMMVMVSANDLLTLFLGLELLSLPLYALAALRRdRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIaka 192

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  78 --SNQTSSTIMTLALAM-------KLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAP----TSLMYQISPSLNMK---M 141
Cdd:PRK05777  193 laDGSGNSLLLLFGLVFllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAfavlLRLLVVAFGGLSEDwqqV 272

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 142 LIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYITT---------TLTLFLALNHSSI 212
Cdd:PRK05777  273 LAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYLLAylfmtlgafGVISLLRRKGGEA 352

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1942250095 213 TKMKSLANLWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRII 285
Cdd:PRK05777  353 ESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 3-180 5.92e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 75.67  E-value: 5.92e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   3 LGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRAT---------ESAIKYFLTQSTASMMLMFAIINNAWMT-NQW 72
Cdd:MTH00198  199 LGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTgNEG 278

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  73 TLSQISNQTSST-------------IMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIapTSLMYQISPSLNM 139
Cdd:MTH00198  279 MLGTILSATLETtnielrqgslgylFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITS 356

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1942250095 140 KMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTI 180
Cdd:MTH00198  357 KLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 2-285 8.51e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.98  E-value: 8.51e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   2 LLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTY-PNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ 80
Cdd:TIGR01770 112 LLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLkRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLF 191

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  81 TSST------------IMTLALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSL-------NMKM 141
Cdd:TIGR01770 192 LSNGmlnisllllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQIF 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 142 LIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTLLN----------LTIYITTTLTLFLALNHSS 211
Cdd:TIGR01770 272 LAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAvlfyifiyalMSLGAFGVLSLLRSYKDEW 351

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1942250095 212 ITKMKSLANLWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRII 285
Cdd:TIGR01770 352 IEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-288 7.57e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 68.64  E-value: 7.57e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISN- 79
Cdd:COG0651   116 LLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAAr 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  80 ---------QTSSTIMTLALAMKLGLAPFHFWVPE--------VT---QGIPLTSGM--ILLTWQKIAPTSLMYQISPsl 137
Cdd:COG0651   196 laeldpgllLAAFALLLVGFGIKAALFPLHFWLPDaypaapspVSallSGLLTKVGVyaILRVLTLLFGADPALFLGT-- 273

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 138 nmkMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWM--------------TIIILINPTL--TLLnltiyITTTL 201
Cdd:COG0651   274 ---LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYIllglglgtplglagALFHLLNHALakALL-----FLAAG 345

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 202 TLFLALNHSSITKMKSLAnlwnKSTPMT-IVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFF 280
Cdd:COG0651   346 AIERATGTRDLDKLGGLG----KRMPLTaAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAY 421


                  ....*...
gi 1942250095 281 YMRIIYTT 288
Cdd:COG0651   422 FVRIFGRA 429
ndhB CHL00049
NADH dehydrogenase subunit 2
 39-183 1.06e-10

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 62.33  E-value: 1.06e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  39 RATESAIKYFLTQSTASMMLMFAI----------INNAWMTNQWTLSQISNQTSSTI----MTLALAMKLGLAPFHFWVP 104
Cdd:CHL00049  159 RSNEATMKYLLMGGASSSILVYGFswlyglsggeIELQEIVNGLINTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 105 EVTQGIPLTSGMILLTWQKIAPTSLMYQIS----PSLNMK---MLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGW 177
Cdd:CHL00049  239 DVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSNEwhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318


                  ....*.
gi 1942250095 178 MTIIIL 183
Cdd:CHL00049  319 VIIGII 324
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 37-180 1.38e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 58.94  E-value: 1.38e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  37 HPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLS-------QISNQTSSTIMT---LALAMKLGLAPFHFWVPEV 106
Cdd:COG1008   156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALTFDiaelaaaPLPLTAQLLLFLaffIAFAVKVPMFPFHTWLPDA 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 107 TQGIPLTSGMIL---------------------LTWQKIAPtslmyqispslnmkMLIILALLSTIMGGWGGLNQTHMRK 165
Cdd:COG1008   236 HVEAPTAGSVLLagvllkmggygllrfalplfpEASAYFAP--------------LLAALGVIGIIYGALVALAQTDLKR 301

                         170
                  ....*....|....*
gi 1942250095 166 ILAYSSIAHMGWMTI 180
Cdd:COG1008   302 LIAYSSVSHMGFVLL 316
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 21-287 1.64e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 55.87  E-value: 1.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  21 LEINTLAIIPMMTYPNH-PRATESAIKYFLTQSTASMMLMFAI---------INNAWMTNQWTLS-QISNQTSSTIMTLA 89
Cdd:PRK08376  150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGIallygqygtLNMAYLAVKMSENpTVVAKIALALFIAG 229

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  90 LAMKLGLAPFHFWVPEVTQGIPLTSGMILLTwQKIAPTSLMYQIS-----PSLNMK----MLIILALLSTIMGGWGGLNQ 160
Cdd:PRK08376  230 LAMKSGAVPVHMWLPDAYPAAPSSISAMLLV-IKQAGLYALARVLfsiygPAINLAtvgwVIIILGCLTMFVGVAMAVVQ 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 161 THMRKILAYSSIAHMGWMTI---IILINPTLTLLNLTIYITTTLTLFLALNH--------------------SSITKMKS 217
Cdd:PRK08376  309 KDVKRLLAYHSVSQIGYMLLglgVGLAALGDPAMASYGEIALAGGIYHIVNHalykallfltagaviyetgtRNLNELGG 388

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 218 LANLWNKSTPMTIVIALmllSLGGLPPLTGFMPKWLILQELITYNNIaMATMMAMSALLNLFFYMRIIYT 287
Cdd:PRK08376  389 LARTMPKTTIAFLIGAA---AIVGLPPFNGFASKWLIYESSALFNPI-LGVIAMIGSVLTLASFVKVFHT 454
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 43-182 1.96e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 55.33  E-value: 1.96e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  43 SAIKYFLTQSTASMMLMFAIINNAWMT------NQWTLSQISNQTSSTIMT---LALAMKLGLAPFHFWVPEV-----TQ 108
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGggtfdlLELLNLPLPFGVQTWLFLaffIAFAVKVPLFPLHTWLPDAhveapTA 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 109 GIPLTSGMILltwqKIAPTSLM---YQISPSLN---MKMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIII 182
Cdd:TIGR01972 237 GSVILAGVLL----KMGTYGFLrfnLPLFPDASlyfAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVLLGI 312
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
38-180 7.66e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 53.52  E-value: 7.66e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  38 PRATESAIKYFLTQSTAS------MMLMFAIINNAWMTNQWTLSQISNQTSSTIMTLAL-----AMKLGLAPFHFWVPEV 106
Cdd:PRK02504  157 PRSNEAALKYLLIGAASSaiflygSSLLYGLSGGSTQLSAIALALITSPSLGLALALVFviagiAFKISAVPFHQWTPDV 236

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 107 TQGIPLTSGMILLTWQKIAPTSL----MYQISPSLNMK---MLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMT 179
Cdd:PRK02504  237 YEGSPTPVVAFLSVGSKAAGFALairlLVTAFPSFDEQwklLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316


                  .
gi 1942250095 180 I 180
Cdd:PRK02504  317 I 317
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 34-180 3.16e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 51.69  E-value: 3.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  34 YPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQ----TSSTIMTLALAM-------KLGLAPFHFW 102
Cdd:COG1009   154 WYEKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELLAAaptiLSSPLLTLILLLlllgafgKSAQFPLHFW 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 103 VPE-----------------VTQGIPLtsgmilltwqkIAPTSLMYQISPSLNMkMLIILALLSTIMGGWGGLNQTHMRK 165
Cdd:COG1009   234 LPDamegptpvsallhaatmVKAGVYL-----------LARLSPLFALSPVWLT-VVAIIGAITALFAALIALAQTDIKR 301

                         170
                  ....*....|....*
gi 1942250095 166 ILAYSSIAHMGWMTI 180
Cdd:COG1009   302 VLAYSTVSQLGYMFL 316
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
1-178 2.84e-06

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 48.93  E-value: 2.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLT---AWM--GLEINTLaiipMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLS 75
Cdd:PRK08168  109 VLAAVHLLVLSDHLLVliaAWAaiSLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLS 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  76 QI-----------SNQTSSTIMTLALAMKLGLAPFHFWVPEVTQ-----------GIPLTSGMILLtwqKIAPtslMYQI 133
Cdd:PRK08168  185 ALwahlaaqgaspSLQAAALLLVLAVILKTAQLPVHGWLIQVMEaptpvsallhaGVVNLGGFVLI---RFAP---LLEQ 258

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1942250095 134 SPSLNMkMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWM 178
Cdd:PRK08168  259 APPARW-LLVLVGLATAVLAGLVMLTRISIKVRLAWSTVAQMGFM 302
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 18-180 1.75e-05

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 46.08  E-value: 1.75e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  18 WMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAII----------NNAWMTNQWT-LSQISNQTSSTIM 86
Cdd:PRK06458  134 WVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTIlvyanaatvmGDGEMAILWTeLLKHASLLDPTLM 213

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  87 TLALAM-------KLGLAPFHFWVPEVTQGIP-----LTSGMIL-------LTWQKIAPTSLMYQISPSLnmkmLIILAL 147
Cdd:PRK06458  214 KLAFVFlligfgtKVGLFPMHAWLPDAHSEAPspvsaLLSGVLLnvalyavLRYYILIDAAIGSDFPGRL----LLIFGL 289

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1942250095 148 LSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTI 180
Cdd:PRK06458  290 LSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAF 322
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-190 1.95e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 45.90  E-value: 1.95e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   1 LLLGTSLTLFSSHWLTAWMGLEINTLAIIPMMTYPNHPRATESAIKYFLTQSTA------SMMLMFAIINNAWMTN--QW 72
Cdd:PRK08676  111 LLSVITFAFFSDNLALFWIFAELTTVFSAMLIAILSARENIDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGtlNW 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  73 T--------LSQISNQTSSTIMTLALAMKLGLAPFHFWVPE-----------VTQGIPLTSGM--ILLTWQKIAPTSLMY 131
Cdd:PRK08676  191 TelaahaslLSPSVLGASFLFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGIygILRLSALLRQSGAAE 270

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1942250095 132 QISPslnmkMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTL 190
Cdd:PRK08676  271 QFSN-----VLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLAL 324
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 47-190 3.28e-05

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 45.30  E-value: 3.28e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  47 YFLTQSTASMMLMFAIINNAWMTNQWTLSQISNQTSSTI-------MTLALAMKLGLAPFHFWVPEVTQGIPLTSGM--- 116
Cdd:MTH00226  190 YTLIGSVLMLLCLFSLYNIHGTTDYLTLASCSHVVSEQTqkwiflgIFLAMAVKIPIFPFHIWLPKAHVEAPVAGSVlla 269

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1942250095 117 -ILLTWQKIAPTSLMYQISP--SLNMKMLII-LALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTL 190
Cdd:MTH00226  270 gILLKLGGYGLVRLSWPILPlgAQNLAPAVIaMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMGLVSITLVTHDIIGL 347
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 279-315 5.09e-05

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 40.32  E-value: 5.09e-05
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1942250095 279 FFYMRIIYTTTLTMPPSTNNSKLQWPHPQTKTTNIIP 315
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLP 37
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 44-182 5.56e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 44.81  E-value: 5.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  44 AIKYFLTQSTASMMLMFAIINNAWMT---------NQWTLSQISNQTSSTIMT---LALAMKLGLAPFHFWVPEV----- 106
Cdd:PRK05846  163 ATKFFLYTLLGSLLMLVAIIYLVVVYynatgtfdiADLLNLPLPPGVQYWLFLaffIAFAVKMPMFPLHTWLPDAhvqap 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 107 TQGIPLTSGmILLtwqKIAPTSL---MYQISPSLNMKMLIILALLSTIM---GGWGGLNQTHMRKILAYSSIAHMGWMTI 180
Cdd:PRK05846  243 TAGSVLLAG-ILL---KMGAYGLlrfSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVTL 318


                  ..
gi 1942250095 181 II 182
Cdd:PRK05846  319 GI 320
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 88-182 2.95e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 42.33  E-value: 2.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  88 LALAMKLGLAPFHFWVP----EVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKM---LIILALLSTIMGGWGGLNQ 160
Cdd:PRK12561  193 IAFGVKLPIFPLHTWLPdahgEASAPVSMILAGVLLKMGGYALIRFNVQMLPDAHVYFapaLAILGVVNIIYGALNAFAQ 272

                          90       100
                  ....*....|....*....|..
gi 1942250095 161 THMRKILAYSSIAHMGWMTIII 182
Cdd:PRK12561  273 DNVKRRLAYSSVSHMGFVLLGI 294
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
88-178 4.03e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.99  E-value: 4.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  88 LALAMKLGLAPFHFWVPE--VTQGIPLTS-------------------GMILLTWQKIAPTslmyqispslnmkmLIILA 146
Cdd:PRK06473  213 VGFGIKIPLVPFHTWLPDahVEASTPVSVllagvllklgtygllrfgvGLFPEAWVYLAPW--------------LATWA 278

                          90       100       110
                  ....*....|....*....|....*....|..
gi 1942250095 147 LLSTIMGGWGGLNQTHMRKILAYSSIAHMGWM 178
Cdd:PRK06473  279 VVSVLYGASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 31-184 4.14e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 42.03  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  31 MMTYPNHPRATESAIKYF-LTQ-STASMMLMFAIINNAwmTNQWTLSQISnqTSSTIMTL-------ALAMKLGLAPFHF 101
Cdd:PRK08667  151 VMNDYQEEETQRAGIFYFvMTQlSTVFLMLGIIVLFIQ--TGSFELSPLG--ASAGILSLvflllflGFGIKAGIIPFHK 226

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 102 WVPEVTQGIP-----LTSGMILLTWQKIAPTSLMYQISPSLNMKMLIILA-LLSTIMGGWGGLNQTHMRKILAYSSIAHM 175
Cdd:PRK08667  227 WLPYAHPASPsnvsaLMSGVMLKVAVYGLVRFLMDVLSPELWWGVLILLAgSISALLGVIYALKEHDLKGLLAYSSIENI 306


                  ....*....
gi 1942250095 176 GwmtiIILI 184
Cdd:PRK08667  307 G----IILM 311
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 2-262 4.55e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 41.91  E-value: 4.55e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095   2 LLGTSLTLFSSHWLTAWMGLEINTLAIIpMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISN-- 79
Cdd:PRK08668  108 LAGVLGVFLANDLLTLYIFWEIMTFSSF-MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQgl 186

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  80 -QTSSTIMTLALAM--------KLGLAPFHFWVPEVTQGIPLT-----SG-------------MILLTWQKIAPTSLMYQ 132
Cdd:PRK08668  187 iNDTSTGFALIVFLfllafgvaKAGIFPLHVWAPDAYSEAPQSfsavlSGqlsklgaygfllvLYVLPGTKLFSEFGTYR 266

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 133 ISPSLNMkMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTL-------LNLTIYITTTLTLFL 205
Cdd:PRK08668  267 GVPLFNY-ILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFagglfhvFNHALFKGLFFLIFA 345

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1942250095 206 ALNH-SSITKMKSLANLWNKsTPMTIVIALMLLSLGGLPPLT-GFMPKWLILQELITYN 262
Cdd:PRK08668  346 AVIYrTGTTKISEMGGLIEK-MPFTFAMYLVAIISLAGIPPMsGFASKWLIFEALISKG 403
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 88-182 4.72e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 41.58  E-value: 4.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  88 LALAMKLGLAPFHFWVPEVTQGIPLTSGMIL--------------LTWqKIAPTSLMYqISPslnmkMLIILALLSTIMG 153
Cdd:MTH00217  214 LSLAIKIPKIPFHIWLPQAHVEAPVAGSVILagvllklggygfirFSW-PLLPEASEY-FSP-----LIQTLSLLAIIYG 286

                          90       100
                  ....*....|....*....|....*....
gi 1942250095 154 GWGGLNQTHMRKILAYSSIAHMGWMTIII 182
Cdd:MTH00217  287 SLTTCRQVDLKRIIAYSSVAHMGLVTLGI 315
PRK12650 PRK12650
DUF4040 family protein;
98-182 5.24e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.95  E-value: 5.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  98 PFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLNMKM-----LIILALLSTIMGGWGGLNQTHMRKILAYSSI 172
Cdd:PRK12650  226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVAvwnwlLIIVGMITALMGAVFAVQKTDLKKLTAYSTV 305

                          90
                  ....*....|
gi 1942250095 173 AHMGWMTIII 182
Cdd:PRK12650  306 SQLGWIVATI 315
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 88-180 7.75e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 41.20  E-value: 7.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  88 LALAMKLGLAPFHFWVPEVTQGIPLTSGMIL--------------LTWqKIAPTSLMYqISPslnmkMLIILALLSTIMG 153
Cdd:MTH00204  217 LSLAVKIPQIPFHIWLPQAHVEAPVAGSVILagillklggygflrFSW-PLFPAASEY-FAP-----LIVMLSVIAVIYG 289

                          90       100
                  ....*....|....*....|....*..
gi 1942250095 154 GWGGLNQTHMRKILAYSSIAHMGWMTI 180
Cdd:MTH00204  290 SLTTCRQVDFKRLIAYSSVAHMGLVPL 316
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 32-300 9.18e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 40.72  E-value: 9.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  32 MTYPNHPRATESAIKYFLTQSTASMMLMFA--IINNAWMT-NQWTLSQISNQTSSTIMT-------LALAMKLGLA---- 97
Cdd:PRK12667  154 AYYRDRGDAVEAAIKYALIGAVGTTLYFLAlaFLYATFGTlNMADLSAKIRGLSFPLTGglagnppLALGVALALAlwaf 233

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  98 -------PFHFWVPEVTQGIP-----LTSGMI-------------LLTWQKIAPTSLMYQISPslnmkMLIILALLSTIM 152
Cdd:PRK12667  234 tikaaifPNHFWLPDAHPAAPspvsaMLSGLVvnvgayaiirflyTIFGISPSLIDFRAALSP-----ILIILGAVSAII 308

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 153 GGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTLLNLTIYI--------TTTLTLFLALNHSSITKMKSLANLWNK 224
Cdd:PRK12667  309 GALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGLGRK 388

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1942250095 225 STPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIYTTTLTMPPSTNNSK 300
Cdd:PRK12667  389 MPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSLFFGKPKSGEEVE 464
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 72-182 1.35e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 40.68  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  72 WTLSQI-SNQTSSTIMTLALAM-------KLGLAPFHFWVPE-----------------VTQGIPLTSgmilltwqKIAP 126
Cdd:PRK12644  187 YRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYLVA--------RLAP 258

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1942250095 127 tslMYQISPSLNMkMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIII 182
Cdd:PRK12644  259 ---GFADVPVWRP-TVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 21-176 1.49e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 40.14  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  21 LEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMF--AIINNAWMT-NQWTLSQISNQTSSTIMTLALAMK-LGL 96
Cdd:PRK08377  137 MEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSSFFLIgvALIYGATGTlNMAHIAQLAGTIDPTVAQVGLALLiFGL 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  97 A------PFHFWVPEVTQGIP------LTSGMILLTWQKIAPTSLMYQISPSLN--MKMLIILALLSTIMGGWGGLNQTH 162
Cdd:PRK08377  217 AveaelfPLNAWAPDAYQAAPhpitvmFSAFVVKAGLYAMARILYLMQNANGWSsvLKLVIIMATLTVFFAELSALRQKN 296

                         170
                  ....*....|....
gi 1942250095 163 MRKILAYSSIAHMG 176
Cdd:PRK08377  297 VKRMIAYSSIGQVG 310
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 140-262 4.76e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 38.56  E-value: 4.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 140 KMLIILALLSTIMGGWGGLNQTHMRKILAYSSIAHMGWMTIIILINPTLTLlnltiyittTLTLFLALNHSSI------- 212
Cdd:PRK12662  280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGL---------AAAVAYIVNHSIVksalfmv 350

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 213 ----------TKMKSLANLWNKSTPMTIVIALMLLSLGGLPPLTGFMPKWLILQELITYN 262
Cdd:PRK12662  351 sgsisyhfgtTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSN 410
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 21-286 5.90e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 38.32  E-value: 5.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  21 LEINTLAIIPMMTYPNHPRATESAIKYFLTQSTASMMLMFAIINNAWMTNQWTLSQISN--------QTSSTIMTLALAM 92
Cdd:PRK08375  135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGalaenptvVTAFGFVLLALAL 214

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  93 KLGLAPFHFWVPE-----------------VTQGIPLTSGMILLTWQKIAPTSLMYQIspslnmkMLIILALLSTIMGGW 155
Cdd:PRK08375  215 KAAVFPLHTWLPRaypaappvvtallsglvTKVAVYALIRIYFTVFGGDFRFALGLGW-------LLAVLALLSMLVGSL 287

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095 156 GGLNQTHMRKILAYSSIAHMGWMTI-IILINPT------LTLLNLTIYITTTLTLF-LALNHSSITKMKSLANLWNKSTP 227
Cdd:PRK08375  288 AALGQDDVKRVLAYSTVSQMGYILLgLALLTPLalaaglLHLLHHALMKGALFLAAgAIEVTYGTRRLSELSGLGRRMPL 367

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1942250095 228 MTIVIALMLLSLGGLPPLTGFMPKWLILQELITYNNIAMATMMAMSALLNLFFYMRIIY 286
Cdd:PRK08375  368 TAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWY 426
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 88-184 6.23e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 38.01  E-value: 6.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1942250095  88 LALAMKLGLAPFHFWVPEVTQGIPLTSGMILLTWQKIAPTSLMYQISPSLN------MKMLIILALLSTIMGGWGGLNQT 161
Cdd:MTH00127  202 LAFLVKMPLYGVHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRMMVMLDpltkelSYPFIILALWGIIMTGSICLRQT 281

                          90       100
                  ....*....|....*....|...
gi 1942250095 162 HMRKILAYSSIAHMGWMTIIILI 184
Cdd:MTH00127  282 DLKSLIAYSSVSHMGLVAGGILI 304
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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