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Conserved domains on  [gi|1099848599|emb|SFH25154|]
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DNA-binding transcriptional regulator, XRE family [Lachnospiraceae bacterium NLAE-zl-G231]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11443570)

helix-turn-helix domain-containing protein such as an XRE (Xenobiotic Response Element) family transcriptional regulator

Gene Ontology:  GO:0003677
PubMed:  37972151

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-77 1.43e-18

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


:

Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 74.26  E-value: 1.43e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGIEEYAVREEPETA 77
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGR-RNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-77 1.43e-18

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 74.26  E-value: 1.43e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGIEEYAVREEPETA 77
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGR-RNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 4-62 1.06e-14

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 63.73  E-value: 1.06e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYL 62
Cdd:cd00093     1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGK-RNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
6-62 4.74e-12

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 56.76  E-value: 4.74e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599    6 RIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYL 62
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGK-RKPSLETLKKLAKALGVSLDEL 56
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 4-63 4.42e-11

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 54.60  E-value: 4.42e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLL 63
Cdd:pfam12844   1 GERLRKAREERGLTQEELAERLGISRSQLSAIENGK-SVPPAETLYKIAELLGVPANWLL 59
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 4-81 1.94e-08

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 51.28  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLG-----LQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGiEEYAVREEPETAL 78
Cdd:PRK13355    5 AERLKQAMKARGLKQEDLVHAAEargvkLGKSHISQYVSGK-TGPRRDVLPFLAAILGVSEDWLLG-GESPADQESDASA 82


                  ...
gi 1099848599  79 LME 81
Cdd:PRK13355   83 VVE 85
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 3-40 3.46e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 40.69  E-value: 3.46e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1099848599   3 IGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRV 40
Cdd:TIGR03830  66 TGPEIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEV 103
 
Name Accession Description Interval E-value
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-77 1.43e-18

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 74.26  E-value: 1.43e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGIEEYAVREEPETA 77
Cdd:COG1396     6 KALGERLRELRKARGLTQEELAERLGVSRSTISRIERGR-RNPSLETLLKLAKALGVSLDELLGGADEELPEALLSE 81
XRE COG1476
DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];
1-67 6.81e-15

DNA-binding transcriptional regulator, XRE-family HTH domain [Transcription];


Pssm-ID: 441085 [Multi-domain]  Cd Length: 68  Bit Score: 64.48  E-value: 6.81e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGIEE 67
Cdd:COG1476     3 KKLGNRLKELRKERGLTQEELAELLGVSRQTISAIENGK-YNPSLELALKIARALGVSLEELFSLEE 68
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 4-62 1.06e-14

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 63.73  E-value: 1.06e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYL 62
Cdd:cd00093     1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGK-RNPSLETLEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
6-62 4.74e-12

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 56.76  E-value: 4.74e-12
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599    6 RIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYL 62
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGK-RKPSLETLKKLAKALGVSLDEL 56
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 4-63 4.42e-11

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 54.60  E-value: 4.42e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLL 63
Cdd:pfam12844   1 GERLRKAREERGLTQEELAERLGISRSQLSAIENGK-SVPPAETLYKIAELLGVPANWLL 59
aMBF1 COG1813
Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and ...
 2-61 5.85e-11

Archaeal ribosome-binding protein aMBF1, putative translation factor, contains Zn-ribbon and HTH domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441418 [Multi-domain]  Cd Length: 70  Bit Score: 54.56  E-value: 5.85e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   2 EIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSY 61
Cdd:COG1813    12 DYGERIREAREARGLSQEELAEKLGVSESTIRRIERGE-ATPSLDTLRKLEKALGISLAE 70
HTH_3 pfam01381
Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and ...
 7-62 7.00e-11

Helix-turn-helix; This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteriztic of the whole family.


Pssm-ID: 460181 [Multi-domain]  Cd Length: 55  Bit Score: 53.70  E-value: 7.00e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1099848599   7 IRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYL 62
Cdd:pfam01381   1 LKELREELGLSQEELAEKLGVSRSTISKIENGK-REPSLETLKKLAEALGVSLDEL 55
YozG COG3655
DNA-binding transcriptional regulator, XRE family [Transcription];
3-67 3.62e-09

DNA-binding transcriptional regulator, XRE family [Transcription];


Pssm-ID: 442872 [Multi-domain]  Cd Length: 69  Bit Score: 49.76  E-value: 3.62e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1099848599   3 IGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSNIKKATLLKMAEILEVSPSYLLGIEE 67
Cdd:COG3655     2 IYVKLDELLAERGMTKKELAEATGISRATLSRLKNGKAKAVRLDTLEKICKALDCQPGDLLEYVP 66
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 2-60 3.99e-09

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 49.45  E-value: 3.99e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1099848599   2 EIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSNIKKATLLKMAEILEVSPS 60
Cdd:pfam13560   1 ELGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGRRGRPSPAVVERLARALGVDGA 59
AF2118 COG3620
Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain ...
 1-67 5.90e-09

Predicted transcriptional regulator, contains an XRE-type HTH domain (archaeal members contain CBS pair) [Transcription];


Pssm-ID: 442838 [Multi-domain]  Cd Length: 95  Bit Score: 50.02  E-value: 5.90e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVsNIKKATLLKMAEILEVSPSYLLGIEE 67
Cdd:COG3620    16 DTLGEALRLMRKELGLSQLPVAELVGVSQSDILRIESGKR-DPTVSTLEKIAEALGKELSAVLVVDD 81
HTH_26 pfam13443
Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to ...
 6-66 8.78e-09

Cro/C1-type HTH DNA-binding domain; This is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433211 [Multi-domain]  Cd Length: 63  Bit Score: 48.69  E-value: 8.78e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1099848599   6 RIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSNIKKATLLKMAEILEVSPSYLLGIE 66
Cdd:pfam13443   1 KLRKLMADRGISKSDLARATGISRATLSRLRKGKPKRVSLDTLDKICDALGCQPGDLLEYV 61
PRK13355 PRK13355
bifunctional HTH-domain containing protein/aminotransferase; Provisional
 4-81 1.94e-08

bifunctional HTH-domain containing protein/aminotransferase; Provisional


Pssm-ID: 237361 [Multi-domain]  Cd Length: 517  Bit Score: 51.28  E-value: 1.94e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLG-----LQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGiEEYAVREEPETAL 78
Cdd:PRK13355    5 AERLKQAMKARGLKQEDLVHAAEargvkLGKSHISQYVSGK-TGPRRDVLPFLAAILGVSEDWLLG-GESPADQESDASA 82


                  ...
gi 1099848599  79 LME 81
Cdd:PRK13355   83 VVE 85
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 1-63 1.12e-07

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 45.95  E-value: 1.12e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSNI-----KKATLLKMAEILEVSPSYLL 63
Cdd:COG1426     4 ETIGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEGDFDALpgpvyVRGFLRSYARALGLDPEELL 71
YiaG COG2944
DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];
4-40 2.28e-06

DNA-binding transcriptional regulator YiaG, XRE-type HTH domain [Transcription];


Pssm-ID: 442187 [Multi-domain]  Cd Length: 64  Bit Score: 42.23  E-value: 2.28e-06
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRV 40
Cdd:COG2944     8 PEEIRALRERLGLSQAEFAALLGVSVSTVRRWEQGRR 44
PRK09706 PRK09706
transcriptional repressor DicA; Reviewed
 3-63 5.18e-06

transcriptional repressor DicA; Reviewed


Pssm-ID: 182039 [Multi-domain]  Cd Length: 135  Bit Score: 42.92  E-value: 5.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1099848599   3 IGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLL 63
Cdd:PRK09706    6 LGQRIRYRRKQLKLSQRSLAKAVKVSHVSISQWERDE-TEPTGKNLFALAKALQCSPTWLL 65
CxxCG_CxxCG_HTH TIGR03830
putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of ...
 3-40 3.46e-05

putative zinc finger/helix-turn-helix protein, YgiT family; This model describes a family of predicted regulatory proteins with a conserved zinc finger/HTH architecture. The amino-terminal region contains a novel domain, featuring two CXXC motifs and occuring in a number of small bacterial proteins as well as in the present family. The carboxyl-terminal region consists of a helix-turn-helix domain, modeled by pfam01381. The predicted function is DNA binding and transcriptional regulation.


Pssm-ID: 274805 [Multi-domain]  Cd Length: 127  Bit Score: 40.69  E-value: 3.46e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1099848599   3 IGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRV 40
Cdd:TIGR03830  66 TGPEIRRIRKKLGLSQREAAELLGGGVNAFSRYERGEV 103
PHA01976 PHA01976
helix-turn-helix protein
 1-64 1.57e-04

helix-turn-helix protein


Pssm-ID: 177330 [Multi-domain]  Cd Length: 67  Bit Score: 37.63  E-value: 1.57e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKG-RVSNIKkaTLLKMAEILEVSPSYLLG 64
Cdd:PHA01976    1 MSFAIQLIKARNARAWSAPELSRRAGVRHSLIYDFEADkRLPNLK--TLLRLADALGVTLDWLCG 63
COG1395 COG1395
Predicted transcriptional regulator [Transcription];
4-90 1.60e-04

Predicted transcriptional regulator [Transcription];


Pssm-ID: 441005 [Multi-domain]  Cd Length: 313  Bit Score: 39.82  E-value: 1.60e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVS-NIKKAtlLKMAEILE---VSPSYLLGIEEYA--VREEPETA 77
Cdd:COG1395   129 GEKLRELREERGLSLGELASELGVSRRTISKYERGEMDaSIEVA--LKLEEILGepiVKPIDILEGAEDLeeAEPTPEDP 206

                          90
                  ....*....|...
gi 1099848599  78 LLMEYYHRLNRKG 90
Cdd:COG1395   207 EEEEILEVLSRLG 219
VapI COG3093
Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense ...
 4-66 3.95e-04

Plasmid maintenance system antidote protein VapI, contains XRE-type HTH domain [Defense mechanisms];


Pssm-ID: 442327 [Multi-domain]  Cd Length: 87  Bit Score: 37.10  E-value: 3.95e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1099848599   4 GERIRR-LRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGIE 66
Cdd:COG3093    10 GEILREeFLEPLGLSQTELAKALGVSRQRISEILNGK-RAITADTALRLARAFGTSAEFWLNLQ 72
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 1-86 4.82e-04

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 38.40  E-value: 4.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1099848599   1 MEIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRvSNIKKATLLKMAEILEVSPSYLLGIEEYAVreePETALLM 80
Cdd:PRK08154   27 AALGERVRTLRARRGMSRKVLAQASGVSERYLAQLESGQ-GNVSILLLRRVARALGCSLADLLGDVDTSS---PDWLLIR 102


                  ....*.
gi 1099848599  81 EYYHRL 86
Cdd:PRK08154  103 ELLEQA 108
couple_hipB TIGR03070
transcriptional regulator, y4mF family; Members of this family belong to a clade of ...
 2-66 6.89e-04

transcriptional regulator, y4mF family; Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions]


Pssm-ID: 213767 [Multi-domain]  Cd Length: 58  Bit Score: 35.71  E-value: 6.89e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1099848599   2 EIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSnikkATLLKMAEILEVspsylLGIE 66
Cdd:TIGR03070   2 QIGILVRARRKALGLTQADLADLAGVGLRFIRDLENGKPT----VRLDKVLRVLDA-----LGLE 57
HTH_37 pfam13744
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain.
 6-55 1.39e-03

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain.


Pssm-ID: 433449 [Multi-domain]  Cd Length: 80  Bit Score: 35.28  E-value: 1.39e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1099848599   6 RIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSNIKKATLLKMAEIL 55
Cdd:pfam13744  22 AIARLIEGRGLSQQEAAALLGIAQPKVSALLKGKLSRFSLDKLLDFLTAL 71
PRK09943 PRK09943
HTH-type transcriptional regulator PuuR;
4-76 1.46e-03

HTH-type transcriptional regulator PuuR;


Pssm-ID: 182158 [Multi-domain]  Cd Length: 185  Bit Score: 36.70  E-value: 1.46e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1099848599   4 GERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGRVSNiKKATLLKMAEILEVSPSyllgiEEYAVREEPET 76
Cdd:PRK09943    9 GKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSP-AISTLQKLLKVYGLSLS-----EFFSEPEKPDE 75
COG1709 COG1709
Predicted transcriptional regulator,contains XRE-type HTH domain [Transcription];
2-39 1.64e-03

Predicted transcriptional regulator,contains XRE-type HTH domain [Transcription];


Pssm-ID: 441315  Cd Length: 234  Bit Score: 36.69  E-value: 1.64e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1099848599   2 EIGERIRRLRKDRHMTQEELAHMLGLQKSAIAKYEKGR 39
Cdd:COG1709    22 DPGETLRKWREDFGISQTELARELGVSPSVISDYESGR 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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