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Conserved domains on  [gi|518149586|ref|WP_019319794|]
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YceD family protein [Streptococcus mutans]

Protein Classification

DUF177 domain-containing protein( domain architecture ID 10495743)

uncharacterized DUF177 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YceD pfam02620
Large ribosomal RNA subunit accumulation protein YceD; This family is nearly universally ...
 54-175 4.87e-24

Large ribosomal RNA subunit accumulation protein YceD; This family is nearly universally conserved in bacteria and plants except the Chlorophyceae algae. Thus far, mutantional analysis in bacteria have not established a function. In contrast, mutants have embryo lethal phenotypes in maize and Arabidopsis. In maize, the mutant embryos arrest at an early transition stage.It has been suggested that family members specifically affect 23S rRNA accumulation in plastids as well as bacteria.


:

Pssm-ID: 460623  Cd Length: 119  Bit Score: 90.89  E-value: 4.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586   54 LNYELTYIITLPSSRSMKPVEQKKIFSINEVFVEN-SQLEAKKDFMDEDLFLILEDDGIDLKESVIDNILLNIPLRVLTK 132
Cdd:pfam02620   1 LDGHVEGTVTLPCDRCLEPVELPLDVDFTELFVPEeEEAEEEELEEEDEEEILYEGDEIDLEELIEEELLLALPMKPLCS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 518149586  133 EEEqEQSLPSGQNWSLLSEEQYQNlqkgKKEKSSP-FAALEGLF 175
Cdd:pfam02620  81 EDC-KGEMLCPVCGANLNEEPCDC----EEEKVDPrFAALAKLK 119
 
Name Accession Description Interval E-value
YceD pfam02620
Large ribosomal RNA subunit accumulation protein YceD; This family is nearly universally ...
 54-175 4.87e-24

Large ribosomal RNA subunit accumulation protein YceD; This family is nearly universally conserved in bacteria and plants except the Chlorophyceae algae. Thus far, mutantional analysis in bacteria have not established a function. In contrast, mutants have embryo lethal phenotypes in maize and Arabidopsis. In maize, the mutant embryos arrest at an early transition stage.It has been suggested that family members specifically affect 23S rRNA accumulation in plastids as well as bacteria.


Pssm-ID: 460623  Cd Length: 119  Bit Score: 90.89  E-value: 4.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586   54 LNYELTYIITLPSSRSMKPVEQKKIFSINEVFVEN-SQLEAKKDFMDEDLFLILEDDGIDLKESVIDNILLNIPLRVLTK 132
Cdd:pfam02620   1 LDGHVEGTVTLPCDRCLEPVELPLDVDFTELFVPEeEEAEEEELEEEDEEEILYEGDEIDLEELIEEELLLALPMKPLCS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 518149586  133 EEEqEQSLPSGQNWSLLSEEQYQNlqkgKKEKSSP-FAALEGLF 175
Cdd:pfam02620  81 EDC-KGEMLCPVCGANLNEEPCDC----EEEKVDPrFAALAKLK 119
YceD COG1399
23S rRNA accumulation protein YceD (essential in plants, uncharacterized in bacteria) ...
 4-178 8.89e-21

23S rRNA accumulation protein YceD (essential in plants, uncharacterized in bacteria) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441009  Cd Length: 169  Bit Score: 83.86  E-value: 8.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586   4 VIDIK--KQAQGISFNEKLAIERAvqQQNPDVLALREVSAKGKVTYDDDFYLLNYELTYIITLPSSRSMKPVEQKKIFSI 81
Cdd:COG1399    7 KIDLAelKAGKGLEFEGEVDLAEL--ERLADLPALGPVRVDLRLEKVGGGVLLTGTVEGTVTLPCDRCLEPFEYPLDVEF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586  82 NEVFVENSQLEAkkdfmDEDLFLILEDDGIDLKESVIDNILLNIPLRVLTKEEEQEqsLPSGQNwslLSEEQYqnlqKGK 161
Cdd:COG1399   85 EELFVFDEEEAE-----EEDEVILLEGDEIDLEELIEEELLLALPMKPLCPEDCKG--LCEGAN---LNEGEC----GCE 150

                        170
                 ....*....|....*...
gi 518149586 162 KEKSSPF-AALEGLFDEK 178
Cdd:COG1399  151 EEKIDPRwAALKKLKKKK 168
 
Name Accession Description Interval E-value
YceD pfam02620
Large ribosomal RNA subunit accumulation protein YceD; This family is nearly universally ...
 54-175 4.87e-24

Large ribosomal RNA subunit accumulation protein YceD; This family is nearly universally conserved in bacteria and plants except the Chlorophyceae algae. Thus far, mutantional analysis in bacteria have not established a function. In contrast, mutants have embryo lethal phenotypes in maize and Arabidopsis. In maize, the mutant embryos arrest at an early transition stage.It has been suggested that family members specifically affect 23S rRNA accumulation in plastids as well as bacteria.


Pssm-ID: 460623  Cd Length: 119  Bit Score: 90.89  E-value: 4.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586   54 LNYELTYIITLPSSRSMKPVEQKKIFSINEVFVEN-SQLEAKKDFMDEDLFLILEDDGIDLKESVIDNILLNIPLRVLTK 132
Cdd:pfam02620   1 LDGHVEGTVTLPCDRCLEPVELPLDVDFTELFVPEeEEAEEEELEEEDEEEILYEGDEIDLEELIEEELLLALPMKPLCS 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 518149586  133 EEEqEQSLPSGQNWSLLSEEQYQNlqkgKKEKSSP-FAALEGLF 175
Cdd:pfam02620  81 EDC-KGEMLCPVCGANLNEEPCDC----EEEKVDPrFAALAKLK 119
YceD COG1399
23S rRNA accumulation protein YceD (essential in plants, uncharacterized in bacteria) ...
 4-178 8.89e-21

23S rRNA accumulation protein YceD (essential in plants, uncharacterized in bacteria) [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441009  Cd Length: 169  Bit Score: 83.86  E-value: 8.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586   4 VIDIK--KQAQGISFNEKLAIERAvqQQNPDVLALREVSAKGKVTYDDDFYLLNYELTYIITLPSSRSMKPVEQKKIFSI 81
Cdd:COG1399    7 KIDLAelKAGKGLEFEGEVDLAEL--ERLADLPALGPVRVDLRLEKVGGGVLLTGTVEGTVTLPCDRCLEPFEYPLDVEF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518149586  82 NEVFVENSQLEAkkdfmDEDLFLILEDDGIDLKESVIDNILLNIPLRVLTKEEEQEqsLPSGQNwslLSEEQYqnlqKGK 161
Cdd:COG1399   85 EELFVFDEEEAE-----EEDEVILLEGDEIDLEELIEEELLLALPMKPLCPEDCKG--LCEGAN---LNEGEC----GCE 150

                        170
                 ....*....|....*...
gi 518149586 162 KEKSSPF-AALEGLFDEK 178
Cdd:COG1399  151 EEKIDPRwAALKKLKKKK 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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