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Conserved domains on  [gi|640470210|ref|WP_024910795|]
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23S rRNA pseudouridine(2605) synthase RluB [Chania multitudinisentens]

Protein Classification

23S rRNA pseudouridine(2605) synthase RluB( domain architecture ID 11484875)

23S rRNA pseudouridine(2605) synthase RluB catalyzes the isomerization of specific uridines in an RNA molecule to pseudouridines

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10700 PRK10700
23S rRNA pseudouridine(2605) synthase RluB;
1-289 0e+00

23S rRNA pseudouridine(2605) synthase RluB;


:

Pssm-ID: 182659 [Multi-domain]  Cd Length: 289  Bit Score: 577.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   1 MSEKLQKVLARAGHGSRREIETMIEAGRVSVDGKIAKLGDRVDASPAMKIRVDGHVVSIKESAEAVCRVLAYYKPEGELC 80
Cdd:PRK10700   1 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  81 TRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGV 160
Cdd:PRK10700  81 TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRQLSRGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 161 QLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKGLPRGGWAELDLKATNYL 240
Cdd:PRK10700 161 QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 640470210 241 RELVELKPETVSKLPVERERRRVKANQIRRAVKRHSQVASGSRRGAPGS 289
Cdd:PRK10700 241 RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNN 289
 
Name Accession Description Interval E-value
PRK10700 PRK10700
23S rRNA pseudouridine(2605) synthase RluB;
1-289 0e+00

23S rRNA pseudouridine(2605) synthase RluB;


Pssm-ID: 182659 [Multi-domain]  Cd Length: 289  Bit Score: 577.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   1 MSEKLQKVLARAGHGSRREIETMIEAGRVSVDGKIAKLGDRVDASPAMKIRVDGHVVSIKESAEAVCRVLAYYKPEGELC 80
Cdd:PRK10700   1 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  81 TRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGV 160
Cdd:PRK10700  81 TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRQLSRGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 161 QLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKGLPRGGWAELDLKATNYL 240
Cdd:PRK10700 161 QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 640470210 241 RELVELKPETVSKLPVERERRRVKANQIRRAVKRHSQVASGSRRGAPGS 289
Cdd:PRK10700 241 RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNN 289
RsuA COG1187
Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ...
 1-233 1.62e-113

Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ribosomal structure and biogenesis]; Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440800 [Multi-domain]  Cd Length: 226  Bit Score: 326.61  E-value: 1.62e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   1 MSEKLQKVLARAGHGSRREIETMIEAGRVSVDGKIAK-LGDRVDasPAMKIRVDGHVVSIKESaeavCRVLAYYKPEGEL 79
Cdd:COG1187    1 EGMRLQKFLANAGVGSRREAEELIEAGRVTVNGKVVTeLGTKVD--PGDEVTVDGKPLKLPEE----PVYLLLNKPAGVV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  80 CTRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRG 159
Cdd:COG1187   75 STTKDPEGRPTVFDLLPEARKERLFPVGRLDKDTEGLLLLTNDGELAHRLTHPKYGVEKEYLVRVDGPVTEEDLERLREG 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640470210 160 VQLEDGPAAFRTISFQGGEGiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLpKGLPRGGWAELD 233
Cdd:COG1187  155 VELEDGPTKPAKVEILSGEA-NTWLRITLTEGRNRQVRRMFEAVGLPVVRLKRVRIGPLTL-GDLPPGEWRELT 226
PseudoU_synth_RluB cd02556
Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and ...
 68-233 5.99e-102

Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and eukaryotic proteins similar to E. coli RluB. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RluB makes psi2605 in 23S RNA. psi2605 has been detected in eubacteria but, not in eukarya and archea despite the presence of a precursor U at that site.


Pssm-ID: 211330 [Multi-domain]  Cd Length: 167  Bit Score: 295.37  E-value: 5.99e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  68 RVLAYYKPEGELCTRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQ 147
Cdd:cd02556    1 RVLIYHKPEGLICTRKDPKGRPTVFDLLPKLGIPRWISVGRLDLNTEGLLLFTNDGELANRLMHPSNEIEREYAVRVFGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 148 IDDEKIKQLNRGVQLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKGLPRG 227
Cdd:cd02556   81 VTDEQLKSLKKGVELEDGFAGFKSIQLEGGEGKNSWYRVTLREGRNREVRRLWEAFGLQVSRLIRIRYGPIFLPGNLKRG 160


                 ....*.
gi 640470210 228 GWAELD 233
Cdd:cd02556  161 QWEELP 166
TIGR00093 TIGR00093
pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that ...
 106-234 1.41e-61

pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that RNA modifications involved in maturing the protein translation apparatus. Counts per genome vary: two in Staphylococcus aureus, three in Pseudomonas putida, four in E. coli, etc. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272902  Cd Length: 128  Bit Score: 191.39  E-value: 1.41e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  106 VGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGVQLEDGPAAFRTISFQGGEGINQWYN 185
Cdd:TIGR00093   1 VGRLDRDSEGLLLLTNDGELVHRLTHPGHHHEKEYLVTVEGPVTDEDLEALRKGVQLEDGKTKPAKLKVITEPGFPTWLR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 640470210  186 VTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLpKGLPRGGWAELDL 234
Cdd:TIGR00093  81 VTLSEGRNRQVRRMFAAVGFPVLRLHRVRIGDVSL-NGLPPGEWRPLTL 128
PseudoU_synth_2 pfam00849
RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA ...
 69-198 2.25e-21

RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA.


Pssm-ID: 459961 [Multi-domain]  Cd Length: 151  Bit Score: 88.23  E-value: 2.25e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   69 VLAYYKPEGELCTRSDPEG---RPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMH--PSREVEREYAVR 143
Cdd:pfam00849   1 YIVVNKPAGVPVHPTDSLTkllSLLALLLRRELGVKRLYPVHRLDKNTSGLLLLAKDGEAANKLNKlfPERKIEKEYLAL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 640470210  144 VFG----------QIDDEKIKQLNRGVQLEDGPAA---FRTISfQGGEGINQWYNVTLTEGRNREVRR 198
Cdd:pfam00849  81 VDKpeeeegtiksPIKKEKNKSPFRKEEELGGKKAvthLKVLK-SGSKGDYSLLELELVTGRKHQIRA 147
S4 smart00363
S4 RNA-binding domain;
5-61 7.78e-05

S4 RNA-binding domain;


Pssm-ID: 214638 [Multi-domain]  Cd Length: 60  Bit Score: 39.88  E-value: 7.78e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 640470210     5 LQKVLARAG-HGSRREIETMIEAGRVSVDGKIAKlgdrvdaSPAMKIRVdGHVVSIKE 61
Cdd:smart00363   3 LDKFLARLGlAPSRSQARRLIEQGRVKVNGKKVT-------KPSYIVKP-GDVISVRG 52
 
Name Accession Description Interval E-value
PRK10700 PRK10700
23S rRNA pseudouridine(2605) synthase RluB;
1-289 0e+00

23S rRNA pseudouridine(2605) synthase RluB;


Pssm-ID: 182659 [Multi-domain]  Cd Length: 289  Bit Score: 577.49  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   1 MSEKLQKVLARAGHGSRREIETMIEAGRVSVDGKIAKLGDRVDASPAMKIRVDGHVVSIKESAEAVCRVLAYYKPEGELC 80
Cdd:PRK10700   1 MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEVTPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELC 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  81 TRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGV 160
Cdd:PRK10700  81 TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRQLSRGV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 161 QLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKGLPRGGWAELDLKATNYL 240
Cdd:PRK10700 161 QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL 240

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 640470210 241 RELVELKPETVSKLPVERERRRVKANQIRRAVKRHSQVASGSRRGAPGS 289
Cdd:PRK10700 241 RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNN 289
RsuA COG1187
Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ...
 1-233 1.62e-113

Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 [Translation, ribosomal structure and biogenesis]; Pseudouridylate synthase RsuA, specific for 16S rRNA U516 and 23S rRNA U2605 is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 440800 [Multi-domain]  Cd Length: 226  Bit Score: 326.61  E-value: 1.62e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   1 MSEKLQKVLARAGHGSRREIETMIEAGRVSVDGKIAK-LGDRVDasPAMKIRVDGHVVSIKESaeavCRVLAYYKPEGEL 79
Cdd:COG1187    1 EGMRLQKFLANAGVGSRREAEELIEAGRVTVNGKVVTeLGTKVD--PGDEVTVDGKPLKLPEE----PVYLLLNKPAGVV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  80 CTRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRG 159
Cdd:COG1187   75 STTKDPEGRPTVFDLLPEARKERLFPVGRLDKDTEGLLLLTNDGELAHRLTHPKYGVEKEYLVRVDGPVTEEDLERLREG 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640470210 160 VQLEDGPAAFRTISFQGGEGiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLpKGLPRGGWAELD 233
Cdd:COG1187  155 VELEDGPTKPAKVEILSGEA-NTWLRITLTEGRNRQVRRMFEAVGLPVVRLKRVRIGPLTL-GDLPPGEWRELT 226
PseudoU_synth_RluB cd02556
Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and ...
 68-233 5.99e-102

Pseudouridine synthase, Escherichia coli RluB like; This group is comprised of bacterial and eukaryotic proteins similar to E. coli RluB. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RluB makes psi2605 in 23S RNA. psi2605 has been detected in eubacteria but, not in eukarya and archea despite the presence of a precursor U at that site.


Pssm-ID: 211330 [Multi-domain]  Cd Length: 167  Bit Score: 295.37  E-value: 5.99e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  68 RVLAYYKPEGELCTRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQ 147
Cdd:cd02556    1 RVLIYHKPEGLICTRKDPKGRPTVFDLLPKLGIPRWISVGRLDLNTEGLLLFTNDGELANRLMHPSNEIEREYAVRVFGQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 148 IDDEKIKQLNRGVQLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKGLPRG 227
Cdd:cd02556   81 VTDEQLKSLKKGVELEDGFAGFKSIQLEGGEGKNSWYRVTLREGRNREVRRLWEAFGLQVSRLIRIRYGPIFLPGNLKRG 160


                 ....*.
gi 640470210 228 GWAELD 233
Cdd:cd02556  161 QWEELP 166
PseudoU_synth_RsuA_like cd02870
Pseudouridine synthases, RsuA subfamily; Pseudouridine synthases are responsible for the ...
 69-215 1.80e-62

Pseudouridine synthases, RsuA subfamily; Pseudouridine synthases are responsible for the synthesis of pseudouridine from uracil in ribosomal RNA. The RsuA subfamily includes Pseudouridine Synthase similar to Ribosomal small subunit pseudouridine 516 synthase. Most of the proteins in this family are bacterial proteins.


Pssm-ID: 211347 [Multi-domain]  Cd Length: 146  Bit Score: 194.25  E-value: 1.80e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  69 VLAYYKPEGELCTRSDPEGRPTVFDrLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQI 148
Cdd:cd02870    1 YLLLNKPRGVVSTVRDPEGRPTVLD-LLKDVGERLFPVGRLDYDTEGLLLLTNDGELANRLTHPRYGVEKTYLVKVRGVP 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 640470210 149 DDEKIKQLNRGVQLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRY 215
Cdd:cd02870   80 SEEELRRLRAGVELDDGKTAPAKVKVLSRDPKNTLLEVTLHEGRNRQVRRMFEAVGHPVLRLKRVRI 146
TIGR00093 TIGR00093
pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that ...
 106-234 1.41e-61

pseudouridine synthase; This model identifies panels of pseudouridine synthase enzymes that RNA modifications involved in maturing the protein translation apparatus. Counts per genome vary: two in Staphylococcus aureus, three in Pseudomonas putida, four in E. coli, etc. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 272902  Cd Length: 128  Bit Score: 191.39  E-value: 1.41e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  106 VGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGVQLEDGPAAFRTISFQGGEGINQWYN 185
Cdd:TIGR00093   1 VGRLDRDSEGLLLLTNDGELVHRLTHPGHHHEKEYLVTVEGPVTDEDLEALRKGVQLEDGKTKPAKLKVITEPGFPTWLR 80

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 640470210  186 VTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLpKGLPRGGWAELDL 234
Cdd:TIGR00093  81 VTLSEGRNRQVRRMFAAVGFPVLRLHRVRIGDVSL-NGLPPGEWRPLTL 128
PseudoU_synth_Rsu_Rlu_like cd02550
Pseudouridine synthase, Rsu/Rlu family; This group is comprised of eukaryotic, bacterial and ...
 69-215 3.08e-54

Pseudouridine synthase, Rsu/Rlu family; This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and TruA. Pseudouridine synthases catalyze the isomerization of specific uridines in a n RNA molecule to pseudouridines (5-ribosyluracil, psi) requiring no cofactors. E. coli RluC for example makes psi955, 2504 and 2580 in 23S RNA. Some psi sites such as psi1917 in 23S RNA made by RluD are universally conserved. Other psi sites occur in a more restricted fashion, for example psi2819 in 21S mitochondrial ribosomal RNA made by S. cerevisiae Pus5p is only found in mitochondrial large subunit rRNAs from some other species and in gram negative bacteria. The E. coli counterpart of this psi residue is psi2580 in 23S rRNA. psi2604in 23S RNA made by RluF has only been detected in E.coli.


Pssm-ID: 211325 [Multi-domain]  Cd Length: 154  Bit Score: 173.33  E-value: 3.08e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  69 VLAYYKPEGELCTRSDPEGRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQI 148
Cdd:cd02550    1 ILVLNKPSGLVCHPTDRDRDPTVVVRLDKLHGPRVHAAGRLDKDTSGLLLLTNDGRLQRRLTEPRREIEKEYLVTVRGEL 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640470210 149 DDEKIKQL-------NRGVQLEDGPAAFRTISFQGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRY 215
Cdd:cd02550   81 DEEGIEDLatvrrgrLSGLVDEGVPLAVTKVRVIGEHGGTGRLRLTLKTGRTHQIRRHCAAVGFPVLRLHRVRI 154
PseudoU_synth_RsuA cd02553
Pseudouridine synthase, Escherichia coli RsuA like; This group is comprised of eukaryotic and ...
 71-232 2.09e-40

Pseudouridine synthase, Escherichia coli RsuA like; This group is comprised of eukaryotic and bacterial proteins similar to Escherichia coli RsuA. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RsuA makes psi516 in 16S RNA. Psi at this position is not generally conserved in other organisms.


Pssm-ID: 211327 [Multi-domain]  Cd Length: 167  Bit Score: 138.42  E-value: 2.09e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  71 AYY---KPEGELCTRSDPEGrPTVFDRLPKLRGSRWV-AVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFG 146
Cdd:cd02553    1 VYLmlnKPAGVVCATKDPHH-PTVIDLLPEPDRRRDLfPVGRLDKDTTGLLLLTNDGQLAHRLTSPKKHVPKTYEVTLAG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 147 QIDDEKIKQLNRGVQLEDG----PAAFRTISfqggegiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPK 222
Cdd:cd02553   80 PLTEDDIEAFAEGVLLHDGyptkPAKLEILS-------PTTVRLTITEGKYHQVKRMFAAVGNKVVALHRIRIGGLELDD 152

                        170
                 ....*....|
gi 640470210 223 GLPRGGWAEL 232
Cdd:cd02553  153 DLAPGEWRPL 162
PRK10475 PRK10475
23S rRNA pseudouridine(2604) synthase RluF;
2-298 9.65e-33

23S rRNA pseudouridine(2604) synthase RluF;


Pssm-ID: 236698 [Multi-domain]  Cd Length: 290  Bit Score: 122.15  E-value: 9.65e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   2 SEKLQKVLARAGHGSRREIETMIEAGRVSVDGKIAKLGDRVdaSPAMKIRVDGHVVSIKESAEAVcrVLAYYKPEGELCT 81
Cdd:PRK10475   6 STRLNKYISESGICSRREADRYIEQGNVFINGKRATIGDQV--KAGDVVKVNGQLIEPREAEDLV--LIALNKPVGIVST 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  82 RSDPEgRPTVFDRLPklRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGVQ 161
Cdd:PRK10475  82 TEDGE-RDNIVDFVN--HSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVP 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 162 L-----------EDGPAAFRtisfqggeginqwynVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLpKGLPRGGWA 230
Cdd:PRK10475 159 IlgtvtkkckvkKEAPFVFR---------------ITLVQGLNRQIRRMCEHFGYEVTKLERTRIMNVSL-SGIPLGEWR 222

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 231 ELDLKatnylrELVELKP--ETVSKLPVERERRRVKANQIRRAVKRHSQVASGSRRGAPGSKPAKSSKRS 298
Cdd:PRK10475 223 DLTDD------ELIDLFKliENSSSEAKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRK 286
PseudoU_synth_RluF cd02554
Pseudouridine synthase, Escherichia coli RluF like; This group is comprised of bacterial ...
 70-232 4.62e-27

Pseudouridine synthase, Escherichia coli RluF like; This group is comprised of bacterial proteins similar to Escherichia coli RluF. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. E.coli RluF makes psi2604 in 23S RNA. psi2604 has only been detected in E. coli. It is absent from other eubacteria despite a precursor U at that site and from eukarya and archea which lack a precursor U at that site.


Pssm-ID: 211328 [Multi-domain]  Cd Length: 164  Bit Score: 103.54  E-value: 4.62e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  70 LAYYKPEGELCTRSDPEgRPTVFDRLPKlrGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQID 149
Cdd:cd02554    3 IAYNKPVGIDCTLERAD-EDNIIDFVNP--PPRIFPIGRLDKDSEGLILLTNDGDLVNKILHADNNHEKEYLVTVNKPIT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 150 DEKIKQLNRGVQLEDG---PAAFRTISFQGgeginqwYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLpKGLPR 226
Cdd:cd02554   80 DEFIEGMSNGVVILGTvtkPCKVERLAKDK-------FRIVLTQGLNRQIRRMCEALGYRVTDLKRVRIMNIEL-GDLAP 151


                 ....*.
gi 640470210 227 GGWAEL 232
Cdd:cd02554  152 GEWRPL 157
PseudoU_synth_RluE cd02566
Pseudouridine synthase, Escherichia coli RluE; This group is comprised of bacterial proteins ...
 69-220 4.79e-27

Pseudouridine synthase, Escherichia coli RluE; This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.


Pssm-ID: 211334 [Multi-domain]  Cd Length: 168  Bit Score: 103.62  E-value: 4.79e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  69 VLAYYKPEGELCT-RSDPEGRPTVFDRL--PKLRgsrwvAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVF 145
Cdd:cd02566    1 LILFNKPYGVLSQfTDESEKHKTLKDYIddPGVY-----AAGRLDRDSEGLLLLTDDGRLQHRITDPSFKHPKTYYVQVE 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 146 GQIDDEKIKQLNRGVQLEDGPA----AFRT------------ISFQgGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSR 209
Cdd:cd02566   76 GVPTEDALEQLRNGVELGDGLTlpakVEKVdeppwlwereppIRFR-KNIPTSWIEITICEGKNRQVRRMTAAVGFPTLR 154

                        170
                 ....*....|.
gi 640470210 210 LIRVRYGDIDL 220
Cdd:cd02566  155 LIRVSIGDIGL 165
PRK10839 PRK10839
16S rRNA pseudouridine(516) synthase RsuA;
4-232 3.91e-24

16S rRNA pseudouridine(516) synthase RsuA;


Pssm-ID: 236774 [Multi-domain]  Cd Length: 232  Bit Score: 97.49  E-value: 3.91e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   4 KLQKVLARAGHGSRREIETMIEAGRVSVDGKIAKLGdRVDASPAMKIRVDGHVVSIKESAeavcRVLAYYKPEGELCTRS 83
Cdd:PRK10839   2 RLDKFISQQLGVSRAIAGRELRANRVTVDGEIVKNG-AFKLLPEHDVAYDGNPLAQQHGP----RYFMLNKPQGYVCSTD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  84 DPEgRPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQIDDEKIKQLNRGVQLE 163
Cdd:PRK10839  77 DPD-HPTVLYFLDEPVAYKLHAAGRLDIDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLH 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 640470210 164 D-----GPAAFRTISfqggegiNQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKGLPRGGWAEL 232
Cdd:PRK10839 156 NekdltKPAVLEVIT-------PTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGAITLDADLAPGEYRPL 222
PseudoU_synth_2 pfam00849
RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA ...
 69-198 2.25e-21

RNA pseudouridylate synthase; Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes RluD, a pseudouridylate synthase that converts specific uracils to pseudouridine in 23S rRNA. RluA from E. coli converts bases in both rRNA and tRNA.


Pssm-ID: 459961 [Multi-domain]  Cd Length: 151  Bit Score: 88.23  E-value: 2.25e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   69 VLAYYKPEGELCTRSDPEG---RPTVFDRLPKLRGSRWVAVGRLDVNTSGLLLFTTDGELANRLMH--PSREVEREYAVR 143
Cdd:pfam00849   1 YIVVNKPAGVPVHPTDSLTkllSLLALLLRRELGVKRLYPVHRLDKNTSGLLLLAKDGEAANKLNKlfPERKIEKEYLAL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 640470210  144 VFG----------QIDDEKIKQLNRGVQLEDGPAA---FRTISfQGGEGINQWYNVTLTEGRNREVRR 198
Cdd:pfam00849  81 VDKpeeeegtiksPIKKEKNKSPFRKEEELGGKKAvthLKVLK-SGSKGDYSLLELELVTGRKHQIRA 147
PRK11394 PRK11394
23S rRNA pseudouridine(2457) synthase RluE;
68-231 4.02e-18

23S rRNA pseudouridine(2457) synthase RluE;


Pssm-ID: 183115  Cd Length: 217  Bit Score: 80.94  E-value: 4.02e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  68 RVLAYYKPEGELCTRSDPEGRPTVFDRLPkLRGSrwVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVFGQ 147
Cdd:PRK11394  40 RVILFNKPYDVLPQFTDEAGRKTLKEFIP-VQGV--YAAGRLDRDSEGLLVLTNNGALQARLTQPGKRTGKIYYVQVEGI 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 148 IDDEKIKQLNRGVQLEDGPAAF--------------RTISFQGGEGI-NQWYNVTLTEGRNREVRRLWEAVGVQVSRLIR 212
Cdd:PRK11394 117 PTQDALEALRNGVTLNDGPTLPagaelvdepawlwpRNPPIRERKSIpTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIR 196

                        170
                 ....*....|....*....
gi 640470210 213 VRYGDIDLpKGLPRGGWAE 231
Cdd:PRK11394 197 YAMGDYSL-DNLANGEWRE 214
PSSA_1 cd02555
Pseudouridine synthase, a subgroup of the RsuA family; This group is comprised of bacterial ...
 73-229 1.70e-17

Pseudouridine synthase, a subgroup of the RsuA family; This group is comprised of bacterial proteins assigned to the RsuA family of pseudouridine synthases. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. The TruA family is comprised of proteins related to Escherichia coli RsuA.


Pssm-ID: 211329 [Multi-domain]  Cd Length: 177  Bit Score: 78.22  E-value: 1.70e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  73 YKPEGELCTRSDP---EGRPTVFDRLPK--LRG--SRWVAVGRLDVNTSGLLLFTTDGELANRLMHPSREVEREYAVRVF 145
Cdd:cd02555   10 HKPAGMVSEQALAllgPGQRSAADRSGRrpLKGhfARLAPIGPLDKDASGLLVFSQDGRVLRKLIGDASRLEQEYLVEVR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210 146 GQIDDEKIKQLNRGVQLEDGPAAFRTISFQGGEGInqwyNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIDLPKgLP 225
Cdd:cd02555   90 GELTAGGLERLNHGLTYDGRELPPAKVSWQNEQRL----RFALKEPQPGQIRRMCESVGLEVVALRRIRIGRVSLGK-LP 164


                 ....
gi 640470210 226 RGGW 229
Cdd:cd02555  165 LGQW 168
S4 cd00165
S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, ...
 5-64 2.75e-06

S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized functional similarity between these three protein classes.


Pssm-ID: 238095 [Multi-domain]  Cd Length: 70  Bit Score: 44.16  E-value: 2.75e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 640470210   5 LQKVLARAG-HGSRREIETMIEAGRVSVDGKIA-KLGDRVDasPAMKIRVDGHVVSIKESAE 64
Cdd:cd00165    3 LDKILARLGlAPSRSEARQLIKHGHVLVNGKVVtKPSYKVK--PGDVIEVDGKSIEEDIVYE 62
S4 pfam01479
S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was ...
 3-45 2.02e-05

S4 domain; The S4 domain is a small domain consisting of 60-65 amino acid residues that was detected in the bacterial ribosomal protein S4, eukaryotic ribosomal S9, two families of pseudouridine synthases, a novel family of predicted RNA methylases, a yeast protein containing a pseudouridine synthetase and a deaminase domain, bacterial tyrosyl-tRNA synthetases, and a number of uncharacterized, small proteins that may be involved in translation regulation. The S4 domain probably mediates binding to RNA.


Pssm-ID: 396182 [Multi-domain]  Cd Length: 48  Bit Score: 41.32  E-value: 2.02e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 640470210    3 EKLQKVLARAGHG-SRREIETMIEAGRVSVDGKIAK-LGDRVDAS 45
Cdd:pfam01479   1 RRLDKVLARLGLAsSRSQARQLIEHGRVLVNGKVVKdPSYRVKPG 45
PseudoU_synth_RluA_like cd02869
Pseudouridine synthase, RluA family; This group is comprised of eukaryotic, bacterial and ...
 69-183 2.52e-05

Pseudouridine synthase, RluA family; This group is comprised of eukaryotic, bacterial and archeal proteins similar to eight site specific Escherichia coli pseudouridine synthases: RsuA, RluA, RluB, RluC, RluD, RluE, RluF and TruA. Pseudouridine synthases catalyze the isomerization of specific uridines in a n RNA molecule to pseudouridines (5-ribosyluracil, psi) requiring no cofactors. E. coli RluC for example makes psi955, 2504 and 2580 in 23S RNA. Some psi sites such as psi1917 in 23S RNA made by RluD are universally conserved. Other psi sites occur in a more restricted fashion, for example psi2819 in 21S mitochondrial ribosomal RNA made by S. cerevisiae Pus5p is only found in mitochondrial large subunit rRNAs from some other species and in gram negative bacteria. The E. coli counterpart of this psi residue is psi2580 in 23S rRNA. psi2604in 23S RNA made by RluF has only been detected in E.coli.


Pssm-ID: 211346 [Multi-domain]  Cd Length: 185  Bit Score: 43.87  E-value: 2.52e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  69 VLAYYKPEGELCTRSDPEGRPTVFDRLPKLR-----GSRWVAVGRLDVNTSGLLLFTTDGELANRL--MHPSREVEREYA 141
Cdd:cd02869    1 LLVVNKPAGLPVHPGPGHLTGTLVNALLKLLlllgeEFRPGLVHRLDKDTSGLLLVAKNKKAAAKLskQFKERKVKKTYL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 640470210 142 VRVFGQIDDEKIKQLNRGVQLEDGPAAFRTISFQGGEGINQW 183
Cdd:cd02869   81 ALVDGKPPEDEGTIDAPLGRKKRKKRARVVVSEDGKPAITHY 122
rluA_subfam TIGR00005
pseudouridine synthase, RluA family; In E. coli, RluD (SfhB) modifies uridine to pseudouridine ...
 1-152 3.16e-05

pseudouridine synthase, RluA family; In E. coli, RluD (SfhB) modifies uridine to pseudouridine at 23S RNA U1911, 1915, and 1917, RluC modifies 955, 2504 and 2580, and RluA modifies U746 and tRNA U32. An additional homolog from E. coli outside this family, TruC (SP|Q46918), modifies uracil-65 in transfer RNAs to pseudouridine. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 161659 [Multi-domain]  Cd Length: 299  Bit Score: 44.62  E-value: 3.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210    1 MSEKLQKVLARA-GHGSRREIETMIEAGRVSVDGKIAklgdrvdASPAMKIRvDGHVVSIKESAEAVCRVLAYY------ 73
Cdd:TIGR00005   4 AGQRLDDFLASLlPDLSRSRIQKLIENGQVKVNGKVT-------ANPKLKVK-DGDRITVRVPEEEEHEVPPQDipldil 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210   74 ----------KPEGELCtrsDPEGR---PTVFDRLPKLRGSRWVA-----VGRLDVNTSGLLLF--TTDG--ELANRLMh 131
Cdd:TIGR00005  76 fedediivinKPSGLVV---HPGGGnpfGTVLNALLAHCPPIAGVervgiVHRLDRDTSGLMVVakTPLAlrELQRQLK- 151

                         170       180
                  ....*....|....*....|.
gi 640470210  132 pSREVEREYAVRVFGQIDDEK 152
Cdd:TIGR00005 152 -NRTVTKEYVALVHGQFDSGG 171
PseudoU_synth_ScRIB2 cd02557
Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2; Pseudouridine synthase, ...
 108-153 3.69e-05

Pseudouridine synthases similar to Saccharomyces cerevisiae RIB2; Pseudouridine synthase, Saccharomyces cerevisiae RIB2_like. This group is comprised of eukaryotic and bacterial proteins similar to Saccharomyces cerevisiae RIB2, S. cerevisiae Pus6p and human hRPUDSD2. S. cerevisiae RIB2 displays two distinct catalytic activities. The N-terminal domain of RIB2 is RNA:psi-synthase which makes psi32 on cytoplasmic tRNAs. Psi32 is highly phylogenetically conserved. The C-terminal domain of RIB2 has a DRAP deaminase activity which catalyses the formation of 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione 5'-phosphate from 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate during riboflavin biosynthesis. S. cerevisiae Pus6p makes the psi31 of cytoplasmic and mitochondrial tRNAs.


Pssm-ID: 211331 [Multi-domain]  Cd Length: 213  Bit Score: 43.77  E-value: 3.69e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 640470210 108 RLDVNTSGLLLFTTDGELANRL--MHPSREVEREYAVRVFGQIDDEKI 153
Cdd:cd02557   65 RLDRLTSGLLLFAKTSQTASRLqqQIRSREVKKEYLARVKGEFPDGEV 112
S4 smart00363
S4 RNA-binding domain;
5-61 7.78e-05

S4 RNA-binding domain;


Pssm-ID: 214638 [Multi-domain]  Cd Length: 60  Bit Score: 39.88  E-value: 7.78e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 640470210     5 LQKVLARAG-HGSRREIETMIEAGRVSVDGKIAKlgdrvdaSPAMKIRVdGHVVSIKE 61
Cdd:smart00363   3 LDKFLARLGlAPSRSQARRLIEQGRVKVNGKKVT-------KPSYIVKP-GDVISVRG 52
RluA COG0564
Pseudouridine synthase RluA, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and ...
 69-152 1.96e-03

Pseudouridine synthase RluA, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]; Pseudouridine synthase RluA, 23S rRNA- or tRNA-specific is part of the Pathway/BioSystem: 23S rRNA modification


Pssm-ID: 440330 [Multi-domain]  Cd Length: 218  Bit Score: 38.58  E-value: 1.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 640470210  69 VLAYYKPEGELCTRSDPEGRPTVFDRL----PKLRGSRWV-AVGRLDVNTSGLLLFTTDGELANRL--MHPSREVEREYA 141
Cdd:COG0564    8 LLVVNKPAGLVVHPGSGGDDGTLVNALrahlGELSGVPRPgLVHRLDRDTSGLLLVAKTRKAARRLseQFREREVEKRYL 87

                         90
                 ....*....|.
gi 640470210 142 VRVFGQIDDEK 152
Cdd:COG0564   88 ALVEGKPKEDE 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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