|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
1-444 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 947.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 1 MFTRVANFCRKVLSREESMANDAIAQPHMSVIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 80
Cdd:PRK11623 8 IFTRVANFCRKVLSREESEAEQAVARPQMTVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 81 FDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEAGVNDRTTSQRGQNGMLLRDNIFGSIEEDAQR 160
Cdd:PRK11623 88 FDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESDRNTSQRGQNGMLLRDNIFGSIEEDAQR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 161 RDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTPETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLIND 240
Cdd:PRK11623 168 RDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLND 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 241 VPPARLFEESLKLLQAGYGFETYNLLREYNLFQPLFPTITRYFTENGDSAMERIIAQVLKNTDTRIHNDMRVNPAFLFAA 320
Cdd:PRK11623 248 IPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 321 MFWYPLLETAQRITQESGLAYYDAFALAANDVLDEGCRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 400
Cdd:PRK11623 328 MFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 407
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 648333072 401 FDLLSLRAEVERNPELQRLAQWWGEFQVSAPPEQKDMLTDLDDE 444
Cdd:PRK11623 408 YDLLALRAEVENNAELQRLAQWWGEFQVSAPPQQKGMLNELDDD 451
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
31-437 |
2.48e-165 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 472.36 E-value: 2.48e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 31 VIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAH 110
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 111 VMFGPEIIEVATFRGHHEAGVNdrttsqrgQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDG 190
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGHKSSVN--------AEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 191 LIRLIGTPETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLINDVPPARLFEESLKLLQAGYGFETYNLLREYN 270
Cdd:TIGR01942 153 RLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 271 LFQPLFPTITRYFTENGDSAMERIIAQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQRITQEsGLAYYDAFALAAN 350
Cdd:TIGR01942 233 LLEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 351 DVLDEGCRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAFDLLSLRAEVERnpELQRLAQWWGEFQVSA 430
Cdd:TIGR01942 312 DFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVCGR--ENAVLGEWWTPYQLAS 389
|
....*..
gi 648333072 431 PPEQKDM 437
Cdd:TIGR01942 390 EEERTEM 396
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
43-427 |
3.23e-126 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 371.84 E-value: 3.23e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 43 DISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFR---NCRLVGRRFRLAHVMFGPEIIE 119
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 120 VATFRGHHEagvndrttSQRGQNGmllrDNIFG-SIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTP 198
Cdd:COG0617 81 VATARTERY--------YGDGRRP----FVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 199 ETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLINDVPPARLFEESLKLLQAGYGFETYNLLREYNLFQPLfpt 278
Cdd:COG0617 149 EERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 279 itryftengdsameriiaqvlkntdtrihndmrvnpAFLFAAMFWypllETAQRITQESGLAYYDAFALAANDVLDEGCR 358
Cdd:COG0617 226 ------------------------------------ALRLAALLH----DLGKPATREDGLPTFHGHEEAGAELAEALLK 265
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648333072 359 TLAIPKRITTLVRDIWQLQLRMSRRQGKRAW---KLMEHpKFRAAFDLLSLRAEVERNPELQ-RLAQW----WGEFQ 427
Cdd:COG0617 266 RLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQeRLAELleaaWRRFQ 341
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
62-193 |
2.00e-50 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 167.46 E-value: 2.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 62 AYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLV----GRRFRLAHVMFGPEIIEVATFRGHH-EAGVNDRTT 136
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFdESDFRNPRS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 648333072 137 SQRGqngmllrdnifGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIR 193
Cdd:pfam01743 81 EEYT-----------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
45-189 |
4.80e-43 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 148.51 E-value: 4.80e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 45 SENALKVLYRLNKA-GYEAYLVGGGVRDLLLGKKPKDFDVTTSA-TPEQVRKLFR--NCRLVGR--RFRLAHVMFGPEII 118
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 648333072 119 EVATFRGHHEAgvndrttsqrgQNGMLLRDNIFGsIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKD 189
Cdd:cd05398 81 DVATLRTETYT-----------DPGRRPPVVGFT-IEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
1-444 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 947.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 1 MFTRVANFCRKVLSREESMANDAIAQPHMSVIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 80
Cdd:PRK11623 8 IFTRVANFCRKVLSREESEAEQAVARPQMTVIPREQHAISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 81 FDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEAGVNDRTTSQRGQNGMLLRDNIFGSIEEDAQR 160
Cdd:PRK11623 88 FDVTTNATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNESDRNTSQRGQNGMLLRDNIFGSIEEDAQR 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 161 RDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTPETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLIND 240
Cdd:PRK11623 168 RDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGNPETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLND 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 241 VPPARLFEESLKLLQAGYGFETYNLLREYNLFQPLFPTITRYFTENGDSAMERIIAQVLKNTDTRIHNDMRVNPAFLFAA 320
Cdd:PRK11623 248 IPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAA 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 321 MFWYPLLETAQRITQESGLAYYDAFALAANDVLDEGCRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 400
Cdd:PRK11623 328 MFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAA 407
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 648333072 401 FDLLSLRAEVERNPELQRLAQWWGEFQVSAPPEQKDMLTDLDDE 444
Cdd:PRK11623 408 YDLLALRAEVENNAELQRLAQWWGEFQVSAPPQQKGMLNELDDD 451
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
31-437 |
2.48e-165 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 472.36 E-value: 2.48e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 31 VIPREQHNISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAH 110
Cdd:TIGR01942 1 VIPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLFRNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 111 VMFGPEIIEVATFRGHHEAGVNdrttsqrgQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDG 190
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGHKSSVN--------AEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 191 LIRLIGTPETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLINDVPPARLFEESLKLLQAGYGFETYNLLREYN 270
Cdd:TIGR01942 153 RLRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQ 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 271 LFQPLFPTITRYFTENGDSAMERIIAQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQRITQEsGLAYYDAFALAAN 350
Cdd:TIGR01942 233 LLEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 351 DVLDEGCRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAFDLLSLRAEVERnpELQRLAQWWGEFQVSA 430
Cdd:TIGR01942 312 DFVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLREVCGR--ENAVLGEWWTPYQLAS 389
|
....*..
gi 648333072 431 PPEQKDM 437
Cdd:TIGR01942 390 EEERTEM 396
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
43-427 |
3.23e-126 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 371.84 E-value: 3.23e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 43 DISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFR---NCRLVGRRFRLAHVMFGPEIIE 119
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRkalRTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 120 VATFRGHHEagvndrttSQRGQNGmllrDNIFG-SIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIRLIGTP 198
Cdd:COG0617 81 VATARTERY--------YGDGRRP----FVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGDP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 199 ETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLINDVPPARLFEESLKLLQAGYGFETYNLLREYNLFQPLfpt 278
Cdd:COG0617 149 EERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL--- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 279 itryftengdsameriiaqvlkntdtrihndmrvnpAFLFAAMFWypllETAQRITQESGLAYYDAFALAANDVLDEGCR 358
Cdd:COG0617 226 ------------------------------------ALRLAALLH----DLGKPATREDGLPTFHGHEEAGAELAEALLK 265
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648333072 359 TLAIPKRITTLVRDIWQLQLRMSRRQGKRAW---KLMEHpKFRAAFDLLSLRAEVERNPELQ-RLAQW----WGEFQ 427
Cdd:COG0617 266 RLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQeRLAELleaaWRRFQ 341
|
|
| PRK13299 |
PRK13299 |
tRNA CCA-pyrophosphorylase; Provisional |
42-273 |
9.61e-52 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237339 [Multi-domain] Cd Length: 394 Bit Score: 179.65 E-value: 9.61e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 42 KDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLVGRRFRLAHVMFGPEIIEVA 121
Cdd:PRK13299 3 PSEFQKALPILEKIKEAGFEAYFVGGSVRDYLLGRPIHDVDIATSAYPEEVKAIFPRTVDVGIEHGTVLVLENGEEYEVT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 122 TFRGhhEAGVND-RTTSQ----RgqngmllrdnifgSIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRLIG 196
Cdd:PRK13299 83 TFRT--ESEYVDyRRPSEvtfvR-------------SLEEDLKRRDFTINAIAMD-ENGEIIDLFDGLEDLKNRLIRAVG 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 648333072 197 TPETRYREDPVRMLRAVRFAAKLNMRISPETAEPIPRLATLINDVPPARLFEESLKLLQAGYGFETYNLLREYNLFQ 273
Cdd:PRK13299 147 NAEERFQEDALRMMRAVRFASQLGFDLETETFEAMKTQAPLLEKISVERIFVEFEKLLLGPFWRKGLKLLIETGLYN 223
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
62-193 |
2.00e-50 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 167.46 E-value: 2.00e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 62 AYLVGGGVRDLLLGKKPKDFDVTTSATPEQVRKLFRNCRLV----GRRFRLAHVMFGPEIIEVATFRGHH-EAGVNDRTT 136
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLFRRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFdESDFRNPRS 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 648333072 137 SQRGqngmllrdnifGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKDGLIR 193
Cdd:pfam01743 81 EEYT-----------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| PolyA_pol_arg_C |
pfam12626 |
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is ... |
337-444 |
3.10e-45 |
|
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is arginine-rich and is necessary for full functioning of the enzyme.
Pssm-ID: 463647 [Multi-domain] Cd Length: 116 Bit Score: 153.51 E-value: 3.10e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 337 SGLAYYDAFALAANDVLDEGCRTLAIPKRITTLVRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAFDLLSLRAEVERnpEL 416
Cdd:pfam12626 1 QGLPPYDALQLAADEVLDEQCQRVAIPRRFTAPMREIWLLQPRLEKRQGKRPFRLLEHPRFRAAYDFLLLRAESGE--VL 78
|
90 100
....*....|....*....|....*...
gi 648333072 417 QRLAQWWGEFQVSAPPEQKDMLTDLDDE 444
Cdd:pfam12626 79 QELAEWWTRFQEADEAEREAMIAELGAD 106
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
45-189 |
4.80e-43 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 148.51 E-value: 4.80e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 45 SENALKVLYRLNKA-GYEAYLVGGGVRDLLLGKKPKDFDVTTSA-TPEQVRKLFR--NCRLVGR--RFRLAHVMFGPEII 118
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDAdGPEFAEALFKkiGGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 648333072 119 EVATFRGHHEAgvndrttsqrgQNGMLLRDNIFGsIEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLKD 189
Cdd:cd05398 81 DVATLRTETYT-----------DPGRRPPVVGFT-IEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| PolyA_pol_RNAbd |
pfam12627 |
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA ... |
220-283 |
1.10e-18 |
|
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA and SrmB binding motifs on polymerase A.
Pssm-ID: 463648 [Multi-domain] Cd Length: 64 Bit Score: 79.84 E-value: 1.10e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 648333072 220 NMRISPETAEPIPRLATLINDVPPARLFEESLKLLQAGYGFETYNLLREYNLFQPLFPTITRYF 283
Cdd:pfam12627 1 GFTIEPETREAIRKLAPLLKKISPERIFEELLKLLLSGHPERGLELLRETGLLEYLFPELAAAL 64
|
|
| cca |
PRK10885 |
multifunctional CCA addition/repair protein; |
63-229 |
7.95e-17 |
|
multifunctional CCA addition/repair protein;
Pssm-ID: 182810 [Multi-domain] Cd Length: 409 Bit Score: 82.21 E-value: 7.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 63 YLVGGGVRDLLLGKKPKDFD-VTTSATPEQVrkLFRNCRLVGRRFRlahVMFGPEIievatfrghHEAGVNDRT--TSQR 139
Cdd:PRK10885 4 YLVGGAVRDALLGLPVKDRDwVVVGATPEEM--LAQGYQQVGKDFP---VFLHPKT---------HEEYALARTerKSGR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 140 GQNGMllrdnIFG-----SIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRLIGTPetrYREDPVRMLRAVR 214
Cdd:PRK10885 70 GYTGF-----TCYaapdvTLEEDLIRRDLTINAMAQD-DDGELIDPYGGQRDLEARLLRHVSPA---FAEDPLRVLRVAR 140
|
170
....*....|....*...
gi 648333072 215 FAAK---LNMRISPETAE 229
Cdd:PRK10885 141 FAARfahLGFRIAPETLA 158
|
|
| PRK13297 |
PRK13297 |
tRNA CCA-pyrophosphorylase; Provisional |
58-249 |
2.58e-15 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 139469 [Multi-domain] Cd Length: 364 Bit Score: 77.34 E-value: 2.58e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 58 AGYEAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVRKlfRNCRLVGRRFRlahVMFGPEII-EVATFRGHHEAGvndrt 135
Cdd:PRK13297 10 AGLQVYIVGGAVRDALLGLPAGDRDwVVVGATPEDMAR--RGFIPVGGDFP---VFLHPRTKeEYALARTERKSG----- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 136 tsqRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVrDYVGGMQDLKDGLIRLIGTPetrYREDPVRMLRAVRF 215
Cdd:PRK13297 80 ---RGYKGFTFYTGADVTLEQDLQRRDLTVNAIARTPQGELV-DPLDGVADVRARVLRHVGEA---FAEDPVRILRLGRF 152
|
170 180 190
....*....|....*....|....*....|....*..
gi 648333072 216 AAKL-NMRISPETAEPIPRL--ATLINDVPPARLFEE 249
Cdd:PRK13297 153 AARFgDFSIAPETMQLCRRMveAGEADALVPERVWKE 189
|
|
| PRK13298 |
PRK13298 |
tRNA CCA-pyrophosphorylase; Provisional |
61-284 |
6.40e-15 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237338 [Multi-domain] Cd Length: 417 Bit Score: 76.31 E-value: 6.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 61 EAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQVrkLFRNCRLVGRRFRlahVMFGPEiievatfrgHHEAGVNDRT--TS 137
Cdd:PRK13298 2 KIYLVGGAVRDSLLNLPVKDKDwVVVGGTPKIL--LSINFQQVGKDFP---VFLHPE---------THEEYALARTerKS 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 138 QRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRLIGTPetrYREDPVRMLRAVRFAA 217
Cdd:PRK13298 68 GVGYTGFITDTSSDVTLEEDLIRRDLTINAIAQD-ENGNYIDPFQGKKDIQLRLLRHVSES---FIEDPLRVLRVARFAA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 648333072 218 K---LNMRISPETAEPIPRLAT---LINdVPPARLFEESLKllqagyGFETYN------LLREYNLFQPLFPTITRYFT 284
Cdd:PRK13298 144 LlvhLGFKIAKETMILMCIMVKkheLLY-LTPERIWNETEK------ALKTDNphvyfqVLYECNALKFLFPEIDFLYE 215
|
|
| PRK13296 |
PRK13296 |
CCA tRNA nucleotidyltransferase; |
61-311 |
1.35e-14 |
|
CCA tRNA nucleotidyltransferase;
Pssm-ID: 106256 [Multi-domain] Cd Length: 360 Bit Score: 75.02 E-value: 1.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 61 EAYLVGGGVRDLLLGKKPKDFD-VTTSATPEQvrklfrncrLVGRRFRLAHVMFgPEIIEVATFRGHHEAGVNDRTTsqR 139
Cdd:PRK13296 2 KFYLVGGAVRDMLLGITPKDKDwVVVGATEDE---------MLANGFIKIAANF-PVFIHPQTKQEYALARSEKKTA--S 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 140 GQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSvADFTVRDYVGGMQDLKDGLIRliGTPETrYREDPVRMLRAVRFAAKL 219
Cdd:PRK13296 70 GYHGFEVNFSKYITLEDDLKRRDLTINSIAID-QNNKVIDPFNGQADLQNRILR--HTSIA-FIEDPLRVVRLARFKAQL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 648333072 220 ---NMRISPETAEPIPRLATL--INDVPPARLFEESLKLLQAGYGFetYNLLREYNLFQPLFPTIT--------RYFTEN 286
Cdd:PRK13296 146 snfNFSIAQEMLALIKELVKTgeLNHLTRERLHIEFVKALNNPKIF--FTTLKELEALKIIFPNIScilplipnKSFFEN 223
|
250 260
....*....|....*....|....*...
gi 648333072 287 G---DSAMERIIAQVLKNTDTRIHNDMR 311
Cdd:PRK13296 224 PiykGSNINEKITLCLLKIPQQQLDDIR 251
|
|
| PHA01806 |
PHA01806 |
hypothetical protein |
28-95 |
6.20e-06 |
|
hypothetical protein
Pssm-ID: 222838 Cd Length: 200 Bit Score: 46.80 E-value: 6.20e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 648333072 28 HMSVIPREQHnISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTT-SATPEQVRKL 95
Cdd:PHA01806 5 HSDLLEGTKE-IPEGLIAKALLLRLYSDARHSEGVALAGGAARDLMHGAEPKDIDIALyGMDDRQAELL 72
|
|
| |
