|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-623 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 554.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 1 MRLFTGFTAVLIFILIFAAMYQQLSREVIQAEPIDrvlseriEFDDVLLAANSRILDRSGTVVSDVYSaENRIFLPYAEI 80
Cdd:COG0744 11 LRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPE-------ELEDLALPQTSTIYDRDGTLIATLGD-ENREWVPLDQI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 81 PGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKLSELLHAYQMEQEM 160
Cdd:COG0744 83 PPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 161 TKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQTMLQRMLAEGH 240
Cdd:COG0744 163 SKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 241 ISEEEAAAAEAESIELN---LRERTDNAPDYVTYVyheleeliaeeegfnrrlesaeeaeRSVIREALADriEQVLQSGV 317
Cdd:COG0744 243 ITQAEADAAKAEPLTLVpppNGAAAGKYPYFVDYV-------------------------RRELEELLGE--DDLYRGGL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 318 TIETAMHPQQQDHVVQQINSRLGNT---GVQAAAAVVDHSAAEITAITGGVGYDKFDFHRGFQSFRQPGSALKPLLsFGP 394
Cdd:COG0744 296 KIYTTLDPKLQKAAEKAVKNVLPEGkpgGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFV-YAA 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 395 YLEEqpNIHAGSVINAGPFSYNG--YTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGFSYLNRLEFSriQEG 472
Cdd:COG0744 375 ALEQ--GYTPATTVDDEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT--SPL 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 473 DEHLPAALGglSEGVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYEWEDRSRRIFETETNQSLRAMLRRVVEDG 552
Cdd:COG0744 451 DPNPSLALG--TSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSG 528
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 651990675 553 TGTEAFYAHeGYLGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRDQRESIVSMSEANAHTGLWRSIMEQLPQ 623
Cdd:COG0744 529 TGRAARLPG-RPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTGGSLPAPIWRDFMEAALE 598
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
71-620 |
1.36e-153 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 452.87 E-value: 1.36e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 71 NRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKLSEL 150
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 151 LHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQT 230
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 231 MLQRMLAEGHISEEEAAAAEAESIELNLRERTDNAPDYVTYVyheleeliaeeegfnrrlesaEEAERSVIREALADrie 310
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKAPYFV---------------------DYVIQELEEEYGEE--- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 311 qVLQSGVTIETAMHPQQQDHVVQQIN------SRLGNTGVQAAAAVVDHSAAEITAITGGVGYDKFDFHRGFQSFRQPGS 384
Cdd:TIGR02074 217 -LYTGGLKIYTTLDLDAQKAAEKVLNtglrvaGRRDGDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGS 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 385 ALKPLLsFGPYLEEqpNIHAGSVINAGPFSYNG---YTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGFSYL 461
Cdd:TIGR02074 296 TFKPFV-YAAALEK--GLTPATIVNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALA 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 462 NRLEF-SRIQEgdeHLPAALGGLSegVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYEWEDRSRRIFETETNQS 540
Cdd:TIGR02074 373 KRFGItSPLDP---VLSLALGTVE--VSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYI 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 541 LRAMLRRVVEDGTGTEAfyAHEGY-LGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRDQRES-IVSMSEANAHTGLWRSIM 618
Cdd:TIGR02074 448 MTDMLKGVVESGTGRSA--RLPGRpVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTlGKSGTGGGLAAPIWRDFM 525
|
..
gi 651990675 619 EQ 620
Cdd:TIGR02074 526 AE 527
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
60-236 |
2.83e-77 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 243.20 E-value: 2.83e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 60 GTVVSdVYSAENRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSH 139
Cdd:pfam00912 2 GTLLA-ELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 140 EQTYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLE 219
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 651990675 220 HPEALKERQQTMLQRML 236
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
68-596 |
1.22e-54 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 199.61 E-value: 1.22e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 68 SAENRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKL 147
Cdd:PRK09506 207 NGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 148 SELLHAYQMEQEMTKEEIFELYLNSIYFA----NGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEA 223
Cdd:PRK09506 287 NEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 224 LKERQQTMLQRMLAEGHISEEEAAAAEAESIELNLR-ERTDNAPDYVTYVyheleeliaeeegfnrrlesaeeaeRSVIR 302
Cdd:PRK09506 367 ALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPKgGVISPQPAFMQMV-------------------------RQELQ 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 303 EALADRIEQVlqSGVTIETAMHPQQQD----HVVQQINSRLGNTGVQ---AAAAVVDHSAAEITAITGGVGYDKFDFHRG 375
Cdd:PRK09506 422 AKLGDKVKDL--SGVKIFTTLDPVSQDaaekAVEEGIPALKKQRKLSdleTAMVVVDRFSGEVRAMVGGSEPQFAGYNRA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 376 FQSFRQPGSALKPllsfGPYLE--EQPN-IHAGSVINAGPFSY---NG--YTPRNFGGGVYGHVTVQEALKNSYNTAAVR 447
Cdd:PRK09506 500 MQARRSIGSLAKP----ATYLTalSQPDkYRLNTWIADAPISLrqpNGqvWSPQNDDRRFSGRVMLVDALTRSMNVPTVN 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 448 MLHDIGISTGFSYLNRLEFSRIQEgdEHLPAALGGlSEGVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYE-WE 526
Cdd:PRK09506 576 LGMALGLPAVTDTWIKLGVPKDQL--NPVPAMLLG-ALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQsFP 652
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 651990675 527 DRSRRIFETETNQSLRAMlRRVVEDGTGTEAFYAHEGY-LGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRD 596
Cdd:PRK09506 653 QAERAVPAQAAYLTLYTM-QQVVQRGTGRQLGAKYPNLhLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRD 722
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-623 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 554.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 1 MRLFTGFTAVLIFILIFAAMYQQLSREVIQAEPIDrvlseriEFDDVLLAANSRILDRSGTVVSDVYSaENRIFLPYAEI 80
Cdd:COG0744 11 LRRLLGLLLLLLAVLVLAALAGLVALYVADLPDPE-------ELEDLALPQTSTIYDRDGTLIATLGD-ENREWVPLDQI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 81 PGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKLSELLHAYQMEQEM 160
Cdd:COG0744 83 PPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTAGGVVQGGSTITQQLVKNLFLSNERTLSRKLKEALLALKLERKY 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 161 TKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQTMLQRMLAEGH 240
Cdd:COG0744 163 SKDEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAALLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGY 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 241 ISEEEAAAAEAESIELN---LRERTDNAPDYVTYVyheleeliaeeegfnrrlesaeeaeRSVIREALADriEQVLQSGV 317
Cdd:COG0744 243 ITQAEADAAKAEPLTLVpppNGAAAGKYPYFVDYV-------------------------RRELEELLGE--DDLYRGGL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 318 TIETAMHPQQQDHVVQQINSRLGNT---GVQAAAAVVDHSAAEITAITGGVGYDKFDFHRGFQSFRQPGSALKPLLsFGP 394
Cdd:COG0744 296 KIYTTLDPKLQKAAEKAVKNVLPEGkpgGLQAALVVVDPKTGEVLAMVGGRDYGKSQFNRATQAKRQPGSTFKPFV-YAA 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 395 YLEEqpNIHAGSVINAGPFSYNG--YTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGFSYLNRLEFSriQEG 472
Cdd:COG0744 375 ALEQ--GYTPATTVDDEPVTFPGggWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT--SPL 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 473 DEHLPAALGglSEGVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYEWEDRSRRIFETETNQSLRAMLRRVVEDG 552
Cdd:COG0744 451 DPNPSLALG--TSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVVTSG 528
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 651990675 553 TGTEAFYAHeGYLGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRDQRESIVSMSEANAHTGLWRSIMEQLPQ 623
Cdd:COG0744 529 TGRAARLPG-RPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGYVTGGSLPAPIWRDFMEAALE 598
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
71-620 |
1.36e-153 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 452.87 E-value: 1.36e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 71 NRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKLSEL 150
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 151 LHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQT 230
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKDRRNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 231 MLQRMLAEGHISEEEAAAAEAESIELNLRERTDNAPDYVTYVyheleeliaeeegfnrrlesaEEAERSVIREALADrie 310
Cdd:TIGR02074 161 VLSNMVENGYITAEEAEEAINEPIQLYLQTKKSEQYKAPYFV---------------------DYVIQELEEEYGEE--- 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 311 qVLQSGVTIETAMHPQQQDHVVQQIN------SRLGNTGVQAAAAVVDHSAAEITAITGGVGYDKFDFHRGFQSFRQPGS 384
Cdd:TIGR02074 217 -LYTGGLKIYTTLDLDAQKAAEKVLNtglrvaGRRDGDDLQAALVAIDPDTGAVRALVGGRDYGKSQFNRATQAKRQPGS 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 385 ALKPLLsFGPYLEEqpNIHAGSVINAGPFSYNG---YTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGFSYL 461
Cdd:TIGR02074 296 TFKPFV-YAAALEK--GLTPATIVNDEPITYNGngpWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALA 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 462 NRLEF-SRIQEgdeHLPAALGGLSegVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYEWEDRSRRIFETETNQS 540
Cdd:TIGR02074 373 KRFGItSPLDP---VLSLALGTVE--VSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYI 447
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 541 LRAMLRRVVEDGTGTEAfyAHEGY-LGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRDQRES-IVSMSEANAHTGLWRSIM 618
Cdd:TIGR02074 448 MTDMLKGVVESGTGRSA--RLPGRpVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTlGKSGTGGGLAAPIWRDFM 525
|
..
gi 651990675 619 EQ 620
Cdd:TIGR02074 526 AE 527
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
3-620 |
3.94e-143 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 434.59 E-value: 3.94e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 3 LFTGFTAVLIFILIFAAMYQQLSREVIQAEpidrvlseriEFDDVLLAANSRILDRSGTVVSDvYSAENRIFLPYAEIPG 82
Cdd:COG5009 8 LILLLLLLLLGALAVAGLYLYLSPDLPDVE----------TLKDYQPPTPSRVYSADGKLIAE-FGEERRIPVPIEEIPP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 83 IVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKLSELLHAYQMEQEMTK 162
Cdd:COG5009 77 LLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRTGRRVQGGSTITQQVAKNFLLSPERTLTRKIKEAILALRIEQELSK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 163 EEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQTMLQRMLAEGHIS 242
Cdd:COG5009 157 DEILELYLNKIYLGHRAYGVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLELGYIT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 243 EEEAAAAEAESIELNLRERT--DNAPdYVT-----YVYHELEELIAEEEGF------NRRL-ESAEEA------------ 296
Cdd:COG5009 237 QAEYEAAKAEPLTARYHGASaeVDAP-YFAemvrrELVERYGEDALYTGGLkvyttlDPRLqEAAEKAlrdgllaydrrh 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 297 -----------ERSVIREALAD------------------RIEQVLQSGVTIE-----------------TAMHPQQQDH 330
Cdd:COG5009 316 gyrgpeahldlAEEDWDEALAEvpdvgdlrpavvlevddkSARVGLRDGETGTlpleglkwarpyindnrRGPAPKSASD 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 331 VVQ---QINSRLGNTG---------VQAAAAVVDHSAAEITAITGGVGYDKFDFHRGFQSFRQPGSALKPLLsfgpY--- 395
Cdd:COG5009 396 VLKpgdVIRVRPVADGgwrlrqipeVQGALVALDPHTGAVLALVGGFDFEQSKFNRATQAKRQPGSSFKPFV----Yaaa 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 396 LEEqpNIHAGSVINAGPFSYNG------YTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGFSYLNRLEF-SR 468
Cdd:COG5009 472 LDN--GYTPATIINDAPIVFDDgggggvWRPKNYSGKFYGPTTLREALEKSRNLVTVRLLQDVGIDYVIDYAERFGIySK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 469 IqegDEHLPAALGglSEGVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYEWE---------------------D 527
Cdd:COG5009 550 L---PPNLSLALG--SGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADparacedcdaaewdgaeprlpD 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 528 RSRRIFETETNQSLRAMLRRVVEDGTGTEAfYAHEGYLGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRDQRESIVSmSEA 607
Cdd:COG5009 625 PAEQVIDPRTAYQMTSMLRGVVQRGTGRRA-RALGRDIAGKTGTTNDSKDAWFVGFTPDLVAGVWVGFDDPRSLGR-GET 702
|
730
....*....|....*
gi 651990675 608 NAHTGL--WRSIMEQ 620
Cdd:COG5009 703 GGRAALpiWIDFMKA 717
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
55-622 |
1.94e-96 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 312.15 E-value: 1.94e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 55 ILDRSGTV-----VSD-VYsaenRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTIT 128
Cdd:COG4953 46 VLDRDGTLlraflAADgQW----RLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIVSGGSTLT 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 129 QQVARNLYlSHEQTYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGI 208
Cdd:COG4953 122 MQVARLLE-PRPRTLSGKLRQILRALQLERRYSKDEILELYLNLAPYGGNIEGVEAASLAYFGKPPSRLSLAEAALLAVL 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 209 PNSPSRYNPLEHPEALKERQQTMLQRMLAEGHISeeeaaaaeAESIELNLRERTDNAPdyvtyvyheleeliaeeegfnr 288
Cdd:COG4953 201 PQAPSRRRPDRNPERARAARDRVLARLAEAGVID--------AEEAALALLEPVPARR---------------------- 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 289 rlesaeeaeRSVIREA--LADRIEQVLQSGVTIETAMHPQQQDHV---VQQINSRLGNTGV-QAAAAVVDHSAAEITAIT 362
Cdd:COG4953 251 ---------RPLPQLAphLARRLLRQLPGGTRIRTTLDAGLQRRLerlVRRYVRRLKQNGIhNAAVLVVDNRTGEVLAYV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 363 GGVGYdkFDFHR-----GFQSFRQPGSALKPL---LSFgpyleEQPNIHAGSVINAGPFSYNGYTPRNFGGGVYGHVTVQ 434
Cdd:COG4953 322 GSADF--FDASRqgqvdMVRALRSPGSTLKPFlygLAL-----DQGLIHPETLLADVPTSFGGYRPENFDGTFQGPVSAR 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 435 EALKNSYNTAAVRMLHDIGISTGFSYLNRLEFSRIQEGDEH--LPAALGGLseGVSVRELTQAYSIFAADGVYRFPRAIR 512
Cdd:COG4953 395 EALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLPPAEHygLSLILGGA--EVTLEELVGLYAALARGGEARPLRLLA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 513 GVFDQhgellyewedRSRRIFETETNQSLRAMLRRVVE-DGTGTEAFYAHEGYLGGKTGTTNDYHDLWFVGSSSTYTTGL 591
Cdd:COG4953 473 GEPAS----------PGRRLLSPGAAWLVRDILSDVPRpDGAFGWRALDSPPPIAWKTGTSYGFRDAWAVGFTGRYTVGV 542
|
570 580 590
....*....|....*....|....*....|.
gi 651990675 592 WMGRDQRESIVSMSEANAHTGLWRSIMEQLP 622
Cdd:COG4953 543 WVGNPDGTPVPGLTGAEAAAPLLFDIFDLLP 573
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
68-621 |
1.43e-82 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 274.67 E-value: 1.43e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 68 SAENRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKL 147
Cdd:TIGR02071 143 NGEQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 148 SELLHAYQMEQEMTKEEIFELYLNSIYF----ANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEA 223
Cdd:TIGR02071 223 NEAYMALILDARYSKDRILELYLNEVYLgqsgDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDR 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 224 LKERQQTMLQRMLAEGHISEEEAAAAEAESieLNLRERTDNAPDYVTYVyheleeliaeeegfnrRLESAEeaersvIRE 303
Cdd:TIGR02071 303 ALERRNLVLRLLQEQKIIDDEEYDMLSARP--LGVQKKGGIISRQPAFL----------------QLVRRE------LRQ 358
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 304 ALADRIEQVlqSGVTIETAMHPQQQDHVVQQINSRL-------GNTGVQAAAAVVDHSAAEITAITGGVGYDKFDFHRGF 376
Cdd:TIGR02071 359 KLGDKVKDL--SGLRIFTTLDPVSQSAAEQAVQETIpalkkkkKLPDLEAAMVVTDRFTGEVRAMVGGSDPQFAGFNRAL 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 377 QSFRQPGSALKPLLsfgpYLE--EQPNI-HAGSVINAGPFSYNG-----YTPRNFGGGVYGHVTVQEALKNSYNTAAVRM 448
Cdd:TIGR02071 437 QARRQIGSLVKPAV----YLTalSQPDKyRLNTWIEDQPLSIKLsngqvWSPQNYDRRYSGTVMLYDALAHSLNIPTVNL 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 449 LHDIGISTGFSYLNRLEFSRIQEgdEHLPAALGGlSEGVSVRELTQAYSIFAADGvYRFP-RAIRGVFDQHGELLYEWED 527
Cdd:TIGR02071 513 GMKVGLPKVSQTWNKLGINKDEI--PPVPSMLLG-AINLTPYEVAQLYQTIASGG-NRAPlSAVRSVLDEDGKVLYQSDP 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 528 RSRRIFETE-TNQSLRAMlRRVVEDGTGtEAFYAHEG--YLGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRDQRESiVSM 604
Cdd:TIGR02071 589 QAEQAVPSQaAYLTLYAM-QQVVQRGTA-RSLGADFPslSLAGKTGTTNDNRDSWFAGIDGKEVTIIWLGRDDNGP-TKL 665
|
570
....*....|....*..
gi 651990675 605 SEANAHTGLWRSIMEQL 621
Cdd:TIGR02071 666 TGASGALQVYARYLSYQ 682
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
60-236 |
2.83e-77 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 243.20 E-value: 2.83e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 60 GTVVSdVYSAENRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSH 139
Cdd:pfam00912 2 GTLLA-ELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIVQGGSTITQQLAKNLFLTP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 140 EQTYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLE 219
Cdd:pfam00912 81 ERTLTRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRGAYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 651990675 220 HPEALKERQQTMLQRML 236
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
55-623 |
4.35e-73 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 248.87 E-value: 4.35e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 55 ILDRSGTVVSdVYSAEN---RIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQV 131
Cdd:TIGR02073 14 VLDRHGTLLR-ALLANDgqwRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRRVSGGSTLTMQL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 132 ARNLYLSHEQTYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNS 211
Cdd:TIGR02073 93 ARLLDPELSRTLTGKLRQMWRAIQLEARYSKREILEAYLNLAPYGGNLEGLRAASLIYFGKEPSSLSLAEAALLAALPQA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 212 PSRYNPLEHPEALKERQQTMLQRMLAEGHISEEEAAAAEAESIeLNLRERTDN-APdyvtyvyHeleeliaeeegFNRRL 290
Cdd:TIGR02073 173 PSARRLDRLPKAAKAARDRLLDRMVEQGPDDSEQVALAALEPL-PALPEPLPQlAP-------H-----------FALKL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 291 ESAEEAERSVIREAladrIEQVLQSgvTIETAmhpqqqdhvVQQINSRLGNTGVQAAAA-VVDHSAAEITAITGGVGYdk 369
Cdd:TIGR02073 234 LRARPEIASVIVST----LDADLQR--RLEEL---------ARRYLSALRPRGISNLAIlVVDNRSGAVLAYVGSADF-- 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 370 FDFHRGFQ-----SFRQPGSALKPLLsFGPYLEEQpNIHAGSVINAGPFSYNGYTPRNFGGGVYGHVTVQEALKNSYNTA 444
Cdd:TIGR02073 297 FDDSNSGQvdgvrAPRSPGSTLKPFL-YALALDDG-LLHPDSLLKDVPLRFGDYAPENFDKTFHGPVPAREALARSLNIP 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 445 AVRMLHDIGISTGFSYLNRLEFSRIQEGDEH--LPAALGGlsEGVSVRELTQAYSIFAADGVYRFPRAIRgvfdqhgell 522
Cdd:TIGR02073 375 AVRLLERVGPPRFADFLRQAGLNLLKPKSDYygLSLALGG--AEITLQDLANLYAMLANQGLSGPLRFLQ---------- 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 523 yewEDRSRRIFETETNQSLRAMLRRVVEDGTGTEAFYAHEGYLGG-----KTGTTNDYHDLWFVGSSSTYTTGLWMGRDQ 597
Cdd:TIGR02073 443 ---TDAKRPERERLLSPGAAWIVLDILKDRPRPDDTLPLSALPTRlplawKTGTSYGFRDAWAAGVSGRYTIGVWVGNFD 519
|
570 580
....*....|....*....|....*.
gi 651990675 598 RESIVSMSEANAHTGLWRSIMEQLPQ 623
Cdd:TIGR02073 520 GKPNPGFFGAAAAAPLLFDILDALQA 545
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
68-596 |
1.22e-54 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 199.61 E-value: 1.22e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 68 SAENRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKL 147
Cdd:PRK09506 207 NGEQRLFVPRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGGSTLTQQLVKNLFLSNERSLWRKA 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 148 SELLHAYQMEQEMTKEEIFELYLNSIYFA----NGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEA 223
Cdd:PRK09506 287 NEAYMALIMDARYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKL 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 224 LKERQQTMLQRMLAEGHISEEEAAAAEAESIELNLR-ERTDNAPDYVTYVyheleeliaeeegfnrrlesaeeaeRSVIR 302
Cdd:PRK09506 367 ALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPKgGVISPQPAFMQMV-------------------------RQELQ 421
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 303 EALADRIEQVlqSGVTIETAMHPQQQD----HVVQQINSRLGNTGVQ---AAAAVVDHSAAEITAITGGVGYDKFDFHRG 375
Cdd:PRK09506 422 AKLGDKVKDL--SGVKIFTTLDPVSQDaaekAVEEGIPALKKQRKLSdleTAMVVVDRFSGEVRAMVGGSEPQFAGYNRA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 376 FQSFRQPGSALKPllsfGPYLE--EQPN-IHAGSVINAGPFSY---NG--YTPRNFGGGVYGHVTVQEALKNSYNTAAVR 447
Cdd:PRK09506 500 MQARRSIGSLAKP----ATYLTalSQPDkYRLNTWIADAPISLrqpNGqvWSPQNDDRRFSGRVMLVDALTRSMNVPTVN 575
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 448 MLHDIGISTGFSYLNRLEFSRIQEgdEHLPAALGGlSEGVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYE-WE 526
Cdd:PRK09506 576 LGMALGLPAVTDTWIKLGVPKDQL--NPVPAMLLG-ALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQsFP 652
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 651990675 527 DRSRRIFETETNQSLRAMlRRVVEDGTGTEAFYAHEGY-LGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRD 596
Cdd:PRK09506 653 QAERAVPAQAAYLTLYTM-QQVVQRGTGRQLGAKYPNLhLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRD 722
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
66-596 |
2.18e-53 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 196.12 E-value: 2.18e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 66 VYSAEN----------RIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNL 135
Cdd:PRK11636 50 VYSADGeliaqygekrRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNF 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 136 YLSHEQTYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRY 215
Cdd:PRK11636 130 FLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLSEMAVIAGLPKAPSTF 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 216 NPLEHPEALKERQQTMLQRMLAEGHISEEEAAAAEAESIELNLR--ERTDNAPdYVTYVYHELEELIAEEEGFN------ 287
Cdd:PRK11636 210 NPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVANYHapEIAFSAP-YLSEMVRQEMYNRYGENAYEdgyrvy 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 288 ----RRLE-SAEEAER-----------------------------------------------SVIREALADRIEQVLQS 315
Cdd:PRK11636 289 ttitRKVQqAAQQAVRnnvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygpllpAVVTSANPQEATAMLAD 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 316 GVTIETAMH-----------------PQQQDHVV---QQINSRLGNTG--------VQAAAAVVDHSAAEITAITGGVGY 367
Cdd:PRK11636 369 GSSVALPMEgvrwarpyrsdtqqgptPRKVTDVVqtgQQIWVRQVDDAwwlaqvpdVNSALVSINPQNGAVMALVGGFDF 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 368 DKFDFHRGFQSFRQPGSALKPLLsFGPYLEEqpNIHAGSVINAGPFSY------NGYTPRNFGGGVYGHVTVQEALKNSY 441
Cdd:PRK11636 449 NQSKFNRATQALRQVGSNIKPFL-YTAAMDK--GLTLASMLNDVPISRwdagagSDWRPKNSPPQYAGPIRLRQGLGQSK 525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 442 NTAAVRMLHDIGISTGFSYLNRLEFSRiQEGDEHLPAALGglSEGVSVRELTQAYSIFAADGVYRFPRAIRGVFDQHGEL 521
Cdd:PRK11636 526 NVVMVRAMRAMGVDYAAEYLQRFGFPA-QNIVHTESLALG--SASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGV 602
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 522 LYE---------------WEDRSRRIFETETN------------------QSLRAMLRRVVEDGTGTEA---------FY 559
Cdd:PRK11636 603 IFEakpkvacpecdipviYGDTQKSNVLENDDvenvatsqeqqnssvpmpQLEQANQALVAQNGAQEYAphvintplaFL 682
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 651990675 560 AHEGY-------------------------LGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRD 596
Cdd:PRK11636 683 IKSALntnifgepgwmgtgwragrdlkrrdIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFD 744
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
62-596 |
1.57e-52 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 192.75 E-value: 1.57e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 62 VVSDVYS--AENRIFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSH 139
Cdd:PRK14850 145 LIAMLYSpeGKKRLFIPRNQYPEMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTIQGGSTLTQQLVKNLFLTN 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 140 EQTYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFA-NG---VYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRY 215
Cdd:PRK14850 225 TRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLGqDGneqIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLY 304
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 216 NPLEHPEALKERQQTMLQRMLAEGHISEEEAAAAEAESieLNLRERTDnapdyvtyvyheleeliaeeegfnrrLESAEE 295
Cdd:PRK14850 305 NPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSRP--LNVQSKGN--------------------------IISSHP 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 296 AERSVIREALADRIEQVLQ--SGVTIETAMHPQQQD-------HVVQQINSRLGNTGVQAAAAVVDHSAAEITAITGGVG 366
Cdd:PRK14850 357 AFIQLVCEEFHKKIHYPFKnfSGTKIFTTLDYISQNaaeqavkIGIPILKRKKRLKDLEVAMVIIDRFSGEVRALIGSSK 436
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 367 YDKFDFHRGFQSFRQPGSALKPLLsfgpYLE--EQPN-IHAGSVINAGPFSY---NG--YTPRNFGGGVYGHVTVQEALK 438
Cdd:PRK14850 437 PEFNGYNRALKARRSIGSLSKPIT----YLTalSQPEkYHLNTWISDTPISIkldNGqyWTPKNNNFSFSGKVMLIDALI 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 439 NSYNTAAVRMLHDIGISTGFSYLNRLEFSRiqEGDEHLPA-ALGGLSegVSVRELTQAYSIFAADGVYRFPRAIRGVFDQ 517
Cdd:PRK14850 513 HSINIPTVHLSINLGLKKLVDSWILLGISS--NYITPLPSiSLGAIN--LTPMEVAQVFQIIGSGGYKSSLSSIRSIISD 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 518 HGELLYEWEDRSRRIFETETNQSLRAMLRRVVEDGTGTE-AFYAHEGYLGGKTGTTNDYHDLWFVGSSSTYTTGLWMGRD 596
Cdd:PRK14850 589 DNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSlGTIFKEFSLAGKTGTTNNLVDSWFVGIDGKQVVITWIGRD 668
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
89-595 |
8.62e-46 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 173.35 E-value: 8.62e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 89 LAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARnLYLSHEQTYERKLSELLHAYQMEQEMTKEEIFEL 168
Cdd:PRK11240 79 INYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVAR-LLDPHPRTFGGKIRQLWRALQLEWHLSKREILTL 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 169 YLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQTMLQRMLAEGHISEEEAAA 248
Cdd:PRK11240 158 YLNRAPFGGTLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERMAEQGVWSAEQVKE 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 249 AEAESIELNLRERTDNAPDyvtyvyheleeliaeeegFNRRLESAEEAErsVIRealadrieqvlqsgVTIETAMHPQQQ 328
Cdd:PRK11240 238 SREEPVWLAPRQMPQLAPL------------------FARMMLGKSKSD--KIV--------------TTLDAGLQRRLE 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 329 DhVVQQINSRLGNTgVQAAAAVVDHSAAEITAITGGVgyDKFDFHRgF------QSFRQPGSALKPLLsFGPYLEEQPnI 402
Cdd:PRK11240 284 D-LALNWKGRLPPR-SSLAMIVVDHTDMAVRGWVGSV--DLNDDSR-FghvdmvNAIRSPGSVLKPFV-YGLALDDGL-I 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 403 HAGSVINAGPFSYNGYTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGiSTGFSYLNR-----LEFSRIQEgdEHLP 477
Cdd:PRK11240 357 HPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYG-PKRFAAKLRnvglpLYLPAGAE--PNLS 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 478 AALGGlsEGVSVRELTQAYSIFAADGvyrfpRAIRGVFdQHGELLYEWEDRS-------RRIFETETNQSLRAMLRRVVE 550
Cdd:PRK11240 434 LILGG--AGARLEDMVAAYSAFARHG-----KAAKLRL-QPDDPLLERPLMSpgaawiiRRIMADEAQPLPDAALPRVVP 505
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 651990675 551 dgtgteafyahegyLGGKTGTTNDYHDLWFVGSSSTYTTGLWMGR 595
Cdd:PRK11240 506 --------------LAWKTGTSYGYRDAWAIGVNARYVIGIWTGR 536
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
63-242 |
1.32e-38 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 142.25 E-value: 1.32e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 63 VSDVYSAENR-IFLPYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIdEGGSTITQQVARNLYLSHEQ 141
Cdd:PRK13481 35 VDELRKIENKsSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDV-QGGSTITQQVVKNYFYDNER 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 142 TYERKLSELLHAYQMEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTT-------SELSLGELSYIGGIPNSPSR 214
Cdd:PRK13481 114 SFTRKVKELFVAHRVEKQYSKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVnknsttmSHITVLQSAILASKVNAPSV 193
|
170 180
....*....|....*....|....*...
gi 651990675 215 YNPLEHPEALKERQQTMLQRMLAEGHIS 242
Cdd:PRK13481 194 YNINDMSENFTQRVSTNLEKMKQQNYIN 221
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
76-235 |
7.33e-38 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 139.90 E-value: 7.33e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 76 PYAEIPGIVKDMFLAVEDRKFYAHQGFDANGIARALMVNLQAGDIDEGGSTITQQVARNLYLSHEQTYERKLSELLHAYQ 155
Cdd:TIGR02070 59 PYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVVRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWM 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 156 MEQEMTKEEIFELYLNSIYFANGVYGIEAAASFYFDKTTSELSLGELSYIGGIPNSPSRYNPLEHPEALKERQQTMLQRM 235
Cdd:TIGR02070 139 LETWWSKQRILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWILKQM 218
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
382-582 |
6.40e-21 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 96.82 E-value: 6.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 382 PGSALKPL--LSFgpyLEEQpNIHAGSVINA-GPFSYNGYTPRNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGF 458
Cdd:COG0768 294 PGSTFKPFtaAAA---LEEG-VITPDTTFDCpGYYRVGGRTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGIDKLY 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 459 SYLNRLEF-------------------SRIQEGDeHLPAALG-GLSegVSVRELTQAYSIFAADGVYRFPRAIRGVFDQH 518
Cdd:COG0768 370 DYLKKFGLgqktgidlpgeasgllpspKRWYPGE-TATMSIGqGLS--VTPLQLAQAYAAIANGGVLVKPHLVKEIVDPD 446
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 651990675 519 GELLYEWEDRSRRIFETETNQSLRAMLRRVVEDGTGTEAFYAHEGY-LGGKTGT-----------TNDYHDLWFVG 582
Cdd:COG0768 447 GEVVKEEPEVLRRVISPETAETVREGMEGVVNEPGGTARRAAIPGYrVAGKTGTaqvvdignggyYKGRHIASFVG 522
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
346-582 |
2.10e-20 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 92.09 E-value: 2.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 346 AAAAVVDHSAAEITAITGGVGYDKFDFH-----RGFQSFRQPGSALKPLLSfGPYLEEQpNIHAGSVINAGPFSYNGYTP 420
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKPSYDPNGFIgplrnRAVTSRYEPGSTFKPFTA-LAALDNG-VLKPDETIFDWPGKQQGGKS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 421 -RNFGGGVYGHVTVQEALKNSYNTAAVRMLHDIGISTGFSYLNRLEFS---RIQEGDEH--------LPAALGGLSEGVS 488
Cdd:pfam00905 79 iGDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYGnktGIGLPGENagyltpywLEGATASFGIGLT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 651990675 489 VR--ELTQAYSIFAADGVYRFPRAIRGVFDQHGELLYewedrSRRIFETETNQSLRAMLRRVVEDGTGTEAFyAHEGY-L 565
Cdd:pfam00905 159 ITplQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVL-----NKLPISKSTAEKVKDMLRLVVNDGTGTGTA-AVPGYkV 232
|
250 260
....*....|....*....|....*...
gi 651990675 566 GGKTGTT-----------NDYHDLWFVG 582
Cdd:pfam00905 233 AGKTGTAqvagpkgggyyDGAQIGWFVG 260
|
|
| |
