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Conserved domains on  [gi|1853298745|ref|WP_174343878|]
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bacterial proteasome activator family protein [Nocardia cyriacigeorgica]

Protein Classification

bacterial proteasome activator family protein( domain architecture ID 10566670)

bacterial proteasome activator family protein similar to Mycobacterium tuberculosis bacterial proteasome activator (Bpa) that is a novel ring-shaped interactor of the mycobacterial proteasome

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BPA pfam10759
Bacterial proteasome activator; This is a family of bacterial proteasome cofactors. The family ...
 46-202 5.55e-102

Bacterial proteasome activator; This is a family of bacterial proteasome cofactors. The family member from Mycobacterium tuberculosis, protein Rv3780, was shown to form rings and cap proteasome core particles. It enhanced peptide and protein degradation by proteasomes in an adenosine triphosphate (ATP)-independent manner, promoting degradation of the heat shock protein repressor HspR.


:

Pssm-ID: 431478  Cd Length: 160  Bit Score: 291.17  E-value: 5.55e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1853298745  46 NDSDERDDSGESLADMVEQPAKVMRIGTMIKQLLEEVRAAPLDDASRARLREIHKSSIRELEQGLAPELREELERLTLPF 125
Cdd:pfam10759   3 AGEDEEEDGEESVTDLVEQPAKVMRIGTMIKQLLEEVRAAPLDEASRARLKEIHERSIKELEDGLAPELVEELERLSLPF 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1853298745 126 TDESVPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRQgALPPG--VHAGDQRSAQHGHTMGGTGQYL 202
Cdd:pfam10759  83 TEDSTPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRR-ALPPGggVAGGPGDPQRAGVGGGGTGQYL 160
 
Name Accession Description Interval E-value
BPA pfam10759
Bacterial proteasome activator; This is a family of bacterial proteasome cofactors. The family ...
 46-202 5.55e-102

Bacterial proteasome activator; This is a family of bacterial proteasome cofactors. The family member from Mycobacterium tuberculosis, protein Rv3780, was shown to form rings and cap proteasome core particles. It enhanced peptide and protein degradation by proteasomes in an adenosine triphosphate (ATP)-independent manner, promoting degradation of the heat shock protein repressor HspR.


Pssm-ID: 431478  Cd Length: 160  Bit Score: 291.17  E-value: 5.55e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1853298745  46 NDSDERDDSGESLADMVEQPAKVMRIGTMIKQLLEEVRAAPLDDASRARLREIHKSSIRELEQGLAPELREELERLTLPF 125
Cdd:pfam10759   3 AGEDEEEDGEESVTDLVEQPAKVMRIGTMIKQLLEEVRAAPLDEASRARLKEIHERSIKELEDGLAPELVEELERLSLPF 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1853298745 126 TDESVPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRQgALPPG--VHAGDQRSAQHGHTMGGTGQYL 202
Cdd:pfam10759  83 TEDSTPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRR-ALPPGggVAGGPGDPQRAGVGGGGTGQYL 160
 
Name Accession Description Interval E-value
BPA pfam10759
Bacterial proteasome activator; This is a family of bacterial proteasome cofactors. The family ...
 46-202 5.55e-102

Bacterial proteasome activator; This is a family of bacterial proteasome cofactors. The family member from Mycobacterium tuberculosis, protein Rv3780, was shown to form rings and cap proteasome core particles. It enhanced peptide and protein degradation by proteasomes in an adenosine triphosphate (ATP)-independent manner, promoting degradation of the heat shock protein repressor HspR.


Pssm-ID: 431478  Cd Length: 160  Bit Score: 291.17  E-value: 5.55e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1853298745  46 NDSDERDDSGESLADMVEQPAKVMRIGTMIKQLLEEVRAAPLDDASRARLREIHKSSIRELEQGLAPELREELERLTLPF 125
Cdd:pfam10759   3 AGEDEEEDGEESVTDLVEQPAKVMRIGTMIKQLLEEVRAAPLDEASRARLKEIHERSIKELEDGLAPELVEELERLSLPF 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1853298745 126 TDESVPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRQgALPPG--VHAGDQRSAQHGHTMGGTGQYL 202
Cdd:pfam10759  83 TEDSTPSDAELRIAQAQLVGWLEGLFHGIQTALFAQQMAARAQLEQMRR-ALPPGggVAGGPGDPQRAGVGGGGTGQYL 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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