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Conserved domains on  [gi|2096799937|ref|WP_223252385|]
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MULTISPECIES: preprotein translocase subunit SecE [Paracoccus]

Protein Classification

preprotein translocase subunit SecE( domain architecture ID 10002155)

preprotein translocase subunit SecE is an essential subunit of the Sec protein translocation channel SecYEG and it clamps together the 2 halves of SecY; may contact the channel plug during translocation

CATH:  1.20.5.1030
Gene Ontology:  GO:0043952|GO:0065002|GO:0006605
TCDB:  3.A.5

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 11-69 5.64e-17

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440454  Cd Length: 68  Bit Score: 67.55  E-value: 5.64e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 2096799937 11 MANPVQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGIL 69
Cdd:COG0690    9 GKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLIL 67
 
Name Accession Description Interval E-value
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 11-69 5.64e-17

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 67.55  E-value: 5.64e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 2096799937 11 MANPVQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGIL 69
Cdd:COG0690    9 GKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLIL 67
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 5-68 7.91e-15

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 61.86  E-value: 7.91e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2096799937  5 KTEGIVMANPVQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGI 68
Cdd:PRK07597   1 LPKMSKMKKLKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLISLL 64
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 15-69 5.92e-13

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 56.67  E-value: 5.92e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 2096799937 15 VQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGIL 69
Cdd:pfam00584  1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 17-68 1.45e-09

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 48.37  E-value: 1.45e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 2096799937 17 FISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGI 68
Cdd:TIGR00964  4 FFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
 
Name Accession Description Interval E-value
SecE COG0690
Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular ...
 11-69 5.64e-17

Preprotein translocase subunit SecE [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440454  Cd Length: 68  Bit Score: 67.55  E-value: 5.64e-17
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 2096799937 11 MANPVQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGIL 69
Cdd:COG0690    9 GKKIVKFFKEVRAELKKVVWPTRKELIQTTLVVLVFVLIFALFLWLVDLLFGWLVSLIL 67
secE PRK07597
preprotein translocase subunit SecE; Reviewed
 5-68 7.91e-15

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 236066  Cd Length: 64  Bit Score: 61.86  E-value: 7.91e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2096799937  5 KTEGIVMANPVQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGI 68
Cdd:PRK07597   1 LPKMSKMKKLKKFFKDVKAELKKVTWPTRKELVRSTIVVLVFVAFFALFFYLVDLLFSKLISLL 64
SecE pfam00584
SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex ...
 15-69 5.92e-13

SecE/Sec61-gamma subunits of protein translocation complex; SecE is part of the SecYEG complex in bacteria which translocates proteins from the cytoplasm. In eukaryotes the complex, made from Sec61-gamma and Sec61-alpha translocates protein from the cytoplasm to the ER. Archaea have a similar complex.


Pssm-ID: 459858  Cd Length: 55  Bit Score: 56.67  E-value: 5.92e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 2096799937 15 VQFISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGIL 69
Cdd:pfam00584  1 KKFFKEVKAELKKVTWPTRKELLKYTVVVLVFVVIMGLFLFLVDLGFSILINLLL 55
secE_bact TIGR00964
preprotein translocase, SecE subunit, bacterial; This model represents exclusively the ...
 17-68 1.45e-09

preprotein translocase, SecE subunit, bacterial; This model represents exclusively the bacterial (and some organellar) SecE protein. SecE is part of the core heterotrimer, SecYEG, of the Sec preprotein translocase system. Other components are the ATPase SecA, a cytosolic chaperone SecB, and an accessory complex of SecDF and YajC. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273367  Cd Length: 55  Bit Score: 48.37  E-value: 1.45e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 2096799937 17 FISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGI 68
Cdd:TIGR00964  4 FFKEVKAELKKVVWPSRKELITYTIVVIVFVLFFSLFLFGIDYVFGKLISLI 55
secE PRK05740
preprotein translocase subunit SecE; Reviewed
 17-70 2.05e-06

preprotein translocase subunit SecE; Reviewed


Pssm-ID: 235587  Cd Length: 92  Bit Score: 40.96  E-value: 2.05e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 2096799937 17 FISQVRAEVGKISWPTRREVITTTIMVFVMATLASIFFFLVDLAIKSGLSGILH 70
Cdd:PRK05740  39 FAKESRTEVRKVVWPTRQETLQTTLIVIAVVIVMALILWGLDSILVWLISFITG 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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