|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
78-483 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 528.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 78 ITPKDFPKNALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFgRQCRLIGRRFRLAHIVFGRDI 157
Cdd:PRK11623 46 ISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLF-RNCRLVGRRFRLAHVMFGPEI 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 158 YEVATFRADHSNHSSDK-ISKVSEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGKLRLIGD 236
Cdd:PRK11623 125 IEVATFRGHHEGNESDRnTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGN 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 237 PVIRYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGLFEQLFP 316
Cdd:PRK11623 205 PETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFP 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 317 VLVPFFTERNDSNAERMLSKALNSTDDRIRDNLRVNPAFLFAALLWYPLREKMEVLKNEGGLNSHDAMMLAANDILAESC 396
Cdd:PRK11623 285 TITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEAC 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 397 KAIALHRRHTSVIRDIWALQFQMTKRSGKRPQQTLEHVKFRAGFDLLVMRAEIEGG-DLVELSAWWHEYQFSNDAQRAEM 475
Cdd:PRK11623 365 RSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDLLALRAEVENNaELQRLAQWWGEFQVSAPPQQKGM 444
|
....*...
gi 2490940235 476 LKAVRNLP 483
Cdd:PRK11623 445 LNELDDDP 452
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
71-478 |
3.21e-157 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 453.49 E-value: 3.21e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 71 VNAGHYDITPKDFPKNALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFgRQCRLIGRRFRLAH 150
Cdd:TIGR01942 2 IPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLF-RNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 151 IVFGRDIYEVATFRADHsnhssdkISKVSEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGK 230
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGH-------KSSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNRR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 231 LRLIGDPVIRYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGL 310
Cdd:TIGR01942 154 LRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 311 FEQLFPVLVPFFTERNDSNAERMLSKALNSTDDRIRDNLRVNPAFLFAALLWYPLREKMEVLKNEgGLNSHDAMMLAAND 390
Cdd:TIGR01942 234 LEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIRD 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 391 ILAESCKAIALHRRHTSVIRDIWALQFQMTKRSGKRPQQTLEHVKFRAGFDLLVMRaEIEGGDLVELSAWWHEYQFSNDA 470
Cdd:TIGR01942 313 FVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLR-EVCGRENAVLGEWWTPYQLASEE 391
|
....*...
gi 2490940235 471 QRAEMLKA 478
Cdd:TIGR01942 392 ERTEMTRS 399
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
82-482 |
9.67e-114 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 341.79 E-value: 9.67e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 82 DFPKNALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFGRQ--CRLIGRRFRLAHIVFGRDIYE 159
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRKAlrTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 160 VATFRADHSNHSSdkiskvseegmllRD--NVYG-TLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGKLRLIGD 236
Cdd:COG0617 81 VATARTERYYGDG-------------RRpfVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGD 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 237 PVIRYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGLFEQLfp 316
Cdd:COG0617 148 PEERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL-- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 317 vlvpffterndsnaermlskalnstddrirdnlrvnpAFLFAALLwYPLREKMEvlkNEGGLNSHDAMMLAANDILAESC 396
Cdd:COG0617 226 -------------------------------------ALRLAALL-HDLGKPAT---REDGLPTFHGHEEAGAELAEALL 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 397 KAIALHRRHTSVIRDIWALQFQMTKRSGKRPQ---QTLEHvKFRAGFDLLVMRAEIEGGDLVE------LSAWWHEYQFS 467
Cdd:COG0617 265 KRLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQerlaelLEAAWRRFQPP 343
|
410 420
....*....|....*....|....*..
gi 2490940235 468 NDAQR------------AEMLKAVRNL 482
Cdd:COG0617 344 VDGEDlmalglkpgpeiGEILRALREA 370
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
101-232 |
3.16e-45 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 154.75 E-value: 3.16e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 101 AYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFgRQCRLI----GRRFRLAHIVFGRDIYEVATFRADH--SNHSSDK 174
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLF-RRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFdeSDFRNPR 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2490940235 175 ISKVSeegmllrdnvyGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGKLR 232
Cdd:pfam01743 80 SEEYT-----------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
84-228 |
1.29e-40 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 142.73 E-value: 1.29e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 84 PKNALVIVEKLQRA-GFEAYVVGGCIRDLLLGHKPKDFDVATNAK-PEEIQKIFGRQ-CRLIGR--RFRLAHIVFGRDIY 158
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDADgPEFAEALFKKIgGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 159 EVATFRADHSNHSSDKISKVSeegmllrdnvyGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKA 228
Cdd:cd05398 81 DVATLRTETYTDPGRRPPVVG-----------FTIEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pcnB |
PRK11623 |
poly(A) polymerase I; Provisional |
78-483 |
0e+00 |
|
poly(A) polymerase I; Provisional
Pssm-ID: 236939 [Multi-domain] Cd Length: 472 Bit Score: 528.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 78 ITPKDFPKNALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFgRQCRLIGRRFRLAHIVFGRDI 157
Cdd:PRK11623 46 ISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKLF-RNCRLVGRRFRLAHVMFGPEI 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 158 YEVATFRADHSNHSSDK-ISKVSEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGKLRLIGD 236
Cdd:PRK11623 125 IEVATFRGHHEGNESDRnTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKEGVIRLIGN 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 237 PVIRYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGLFEQLFP 316
Cdd:PRK11623 205 PETRYREDPVRMLRAVRFAAKLDMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEYHLFQPLFP 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 317 VLVPFFTERNDSNAERMLSKALNSTDDRIRDNLRVNPAFLFAALLWYPLREKMEVLKNEGGLNSHDAMMLAANDILAESC 396
Cdd:PRK11623 285 TITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLEHAQKIAQESGLAYYDAFALAMNDVLDEAC 364
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 397 KAIALHRRHTSVIRDIWALQFQMTKRSGKRPQQTLEHVKFRAGFDLLVMRAEIEGG-DLVELSAWWHEYQFSNDAQRAEM 475
Cdd:PRK11623 365 RSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLMEHPKFRAAYDLLALRAEVENNaELQRLAQWWGEFQVSAPPQQKGM 444
|
....*...
gi 2490940235 476 LKAVRNLP 483
Cdd:PRK11623 445 LNELDDDP 452
|
|
| pcnB |
TIGR01942 |
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as ... |
71-478 |
3.21e-157 |
|
poly(A) polymerase; This model describes the pcnB family of poly(A) polymerases (also known as plasmid copy number protein). These enzymes sequentially add adenosine nucleotides to the 3' end of RNAs, targeting them for degradation by the cell. This was originally described for anti-sense RNAs, but was later demonstrated for mRNAs as well. Members of this family are as yet limited to the gamma- and beta-proteobacteria, with putative members in the Chlamydiacae and spirochetes. This family has homology to tRNA nucleotidyltransferase (cca).
Pssm-ID: 130997 [Multi-domain] Cd Length: 410 Bit Score: 453.49 E-value: 3.21e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 71 VNAGHYDITPKDFPKNALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFgRQCRLIGRRFRLAH 150
Cdd:TIGR01942 2 IPESEHNIPRQSFSAHALNVVERLKGAGYQAYIVGGAVRDLLLGIEPKDFDVVTSATPEEVRKLF-RNSRIVGRRFRLVH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 151 IVFGRDIYEVATFRADHsnhssdkISKVSEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGK 230
Cdd:TIGR01942 81 VSFGRQIIEVATFRSGH-------KSSVNAEGRILKDNVYGTLEEDAWRRDFTVNALYYDPSREVIIDYVGGMEDLKNRR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 231 LRLIGDPVIRYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGL 310
Cdd:TIGR01942 154 LRLIGDPRSRYQEDPVRMLRALRFSVKLEFTIDESTARPIRESAPLLKGIPPARLFEEILKLLFSGRSAALFRMLCGYQL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 311 FEQLFPVLVPFFTERNDSNAERMLSKALNSTDDRIRDNLRVNPAFLFAALLWYPLREKMEVLKNEgGLNSHDAMMLAAND 390
Cdd:TIGR01942 234 LEPLFPSVAYALRESPKFESAFTVQALVNDTDFRVKRDKPVTPAFLYAALLWPGLVFRVADAPDQ-GVMPYPAVFDAIRD 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 391 ILAESCKAIALHRRHTSVIRDIWALQFQMTKRSGKRPQQTLEHVKFRAGFDLLVMRaEIEGGDLVELSAWWHEYQFSNDA 470
Cdd:TIGR01942 313 FVEEQCAPISIPKRFSIPTREIWQMQLRLERRSGMRARKLLGHARFRAAYDLLLLR-EVCGRENAVLGEWWTPYQLASEE 391
|
....*...
gi 2490940235 471 QRAEMLKA 478
Cdd:TIGR01942 392 ERTEMTRS 399
|
|
| PcnB |
COG0617 |
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and ... |
82-482 |
9.67e-114 |
|
tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; tRNA nucleotidyltransferase/poly(A) polymerase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440382 [Multi-domain] Cd Length: 391 Bit Score: 341.79 E-value: 9.67e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 82 DFPKNALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFGRQ--CRLIGRRFRLAHIVFGRDIYE 159
Cdd:COG0617 1 RLSPNALKVLEALEEAGFEAYLVGGAVRDLLLGRPPKDIDIVTVATPEEVAALFRKAlrTVPVGRDFGTVTVVFGGEKIE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 160 VATFRADHSNHSSdkiskvseegmllRD--NVYG-TLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGKLRLIGD 236
Cdd:COG0617 81 VATARTERYYGDG-------------RRpfVEFGdTLEEDLARRDFTINALAYDLNDGELIDPFGGLADLEARVIRTVGD 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 237 PVIRYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGLFEQLfp 316
Cdd:COG0617 148 PEERFREDPLRILRAVRFAARLGFTIEPETLAAIREMAGLLDRLSAERVWDELLKLLLSPHPSRGLELLRETGLLEVL-- 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 317 vlvpffterndsnaermlskalnstddrirdnlrvnpAFLFAALLwYPLREKMEvlkNEGGLNSHDAMMLAANDILAESC 396
Cdd:COG0617 226 -------------------------------------ALRLAALL-HDLGKPAT---REDGLPTFHGHEEAGAELAEALL 264
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 397 KAIALHRRHTSVIRDIWALQFQMTKRSGKRPQ---QTLEHvKFRAGFDLLVMRAEIEGGDLVE------LSAWWHEYQFS 467
Cdd:COG0617 265 KRLRLPNRERKLVRELVELHLRFHGLGELRDSavrRLLER-GPEALEDLLLLRENGLEYPELQerlaelLEAAWRRFQPP 343
|
410 420
....*....|....*....|....*..
gi 2490940235 468 NDAQR------------AEMLKAVRNL 482
Cdd:COG0617 344 VDGEDlmalglkpgpeiGEILRALREA 370
|
|
| PRK13299 |
PRK13299 |
tRNA CCA-pyrophosphorylase; Provisional |
80-322 |
1.70e-50 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237339 [Multi-domain] Cd Length: 394 Bit Score: 177.34 E-value: 1.70e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 80 PKDFPKnALVIVEKLQRAGFEAYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFGRQCRlIGRRFRLAHIVFGRDIYE 159
Cdd:PRK13299 3 PSEFQK-ALPILEKIKEAGFEAYFVGGSVRDYLLGRPIHDVDIATSAYPEEVKAIFPRTVD-VGIEHGTVLVLENGEEYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 160 VATFRADHSNHSSDKISKVSeegmLLRDnvygtLREDAQRRDFTVNSLYYDpKHNLIFDFFDGIADLKAGKLRLIGDPVI 239
Cdd:PRK13299 81 VTTFRTESEYVDYRRPSEVT----FVRS-----LEEDLKRRDFTINAIAMD-ENGEIIDLFDGLEDLKNRLIRAVGNAEE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 240 RYQEDPVRMLRAVRFMAKLDMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQ---SGQGFktyQLMRQYGLFEQLfp 316
Cdd:PRK13299 151 RFQEDALRMMRAVRFASQLGFDLETETFEAMKTQAPLLEKISVERIFVEFEKLLLgpfWRKGL---KLLIETGLYNYL-- 225
|
....*.
gi 2490940235 317 vlvPFF 322
Cdd:PRK13299 226 ---PGL 228
|
|
| PolyA_pol |
pfam01743 |
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, ... |
101-232 |
3.16e-45 |
|
Poly A polymerase head domain; This family includes nucleic acid independent RNA polymerases, such as Poly(A) polymerase, which adds the poly (A) tail to mRNA EC:2.7.7.19. This family also includes the tRNA nucleotidyltransferase that adds the CCA to the 3' of the tRNA EC:2.7.7.25. This family is part of the nucleotidyltransferase superfamily.
Pssm-ID: 396348 [Multi-domain] Cd Length: 126 Bit Score: 154.75 E-value: 3.16e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 101 AYVVGGCIRDLLLGHKPKDFDVATNAKPEEIQKIFgRQCRLI----GRRFRLAHIVFGRDIYEVATFRADH--SNHSSDK 174
Cdd:pfam01743 1 LYIVGGAVRDLLLGKTPKDVDIATDATPEQVATLF-RRRRIVhllsGIEFGTIHVIFGNQILEVATFRIEFdeSDFRNPR 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2490940235 175 ISKVSeegmllrdnvyGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKAGKLR 232
Cdd:pfam01743 80 SEEYT-----------GTLEEDAKRRDFTINALAYNPNSGEVIDYFGGIKDLKSGVIR 126
|
|
| PolyA_pol_arg_C |
pfam12626 |
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is ... |
376-483 |
3.69e-42 |
|
Polymerase A arginine-rich C-terminus; The C-terminus of polymerase A in E coli is arginine-rich and is necessary for full functioning of the enzyme.
Pssm-ID: 463647 [Multi-domain] Cd Length: 116 Bit Score: 146.19 E-value: 3.69e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 376 GGLNSHDAMMLAANDILAESCKAIALHRRHTSVIRDIWALQFQMTKRSGKRPQQTLEHVKFRAGFDLLVMRAEIeGGDLV 455
Cdd:pfam12626 1 QGLPPYDALQLAADEVLDEQCQRVAIPRRFTAPMREIWLLQPRLEKRQGKRPFRLLEHPRFRAAYDFLLLRAES-GEVLQ 79
|
90 100
....*....|....*....|....*...
gi 2490940235 456 ELSAWWHEYQFSNDAQRAEMLKAVRNLP 483
Cdd:pfam12626 80 ELAEWWTRFQEADEAEREAMIAELGADA 107
|
|
| NT_ClassII-CCAase |
cd05398 |
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the ... |
84-228 |
1.29e-40 |
|
Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; CCA-adding enzymes add the sequence [cytidine(C)-cytidine-adenosine (A)], one nucleotide at a time, onto the 3' end of tRNA, in a template-independent reaction. This Class II group is comprised mainly of eubacterial and eukaryotic enzymes and includes Bacillus stearothermophilus CCAase, Escherichia coli poly(A) polymerase I, human mitochondrial CCAase, and Saccharomyces cerevisiae CCAase (CCA1). CCA-adding enzymes have a single catalytic pocket, which recognizes both ATP and CTP substrates. Included in this subgroup are CC- and A-adding enzymes from various ancient species of bacteria such as Aquifex aeolicus; these enzymes collaborate to add CCA to tRNAs. This family belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These carboxylate residues are fairly well conserved in this family. Escherichia coli CCAase is related to this group but has not been included in this alignment as this enzyme lacks the N-terminal helix conserved in the remainder of the NT superfamily.
Pssm-ID: 143388 [Multi-domain] Cd Length: 139 Bit Score: 142.73 E-value: 1.29e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 84 PKNALVIVEKLQRA-GFEAYVVGGCIRDLLLGHKPKDFDVATNAK-PEEIQKIFGRQ-CRLIGR--RFRLAHIVFGRDIY 158
Cdd:cd05398 1 TPELLKLLRELKKAlGYEAYLVGGAVRDLLLGRPPKDIDIATDADgPEFAEALFKKIgGRVVGLgeEFGTATVVINGLTI 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 159 EVATFRADHSNHSSDKISKVSeegmllrdnvyGTLREDAQRRDFTVNSLYYDPKHNLIFDFFDGIADLKA 228
Cdd:cd05398 81 DVATLRTETYTDPGRRPPVVG-----------FTIEEDLLRRDFTINAMAYDLDDGELIDPFGGLKDLEN 139
|
|
| PolyA_pol_RNAbd |
pfam12627 |
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA ... |
259-322 |
4.45e-19 |
|
Probable RNA and SrmB- binding site of polymerase A; This region encompasses much of the RNA and SrmB binding motifs on polymerase A.
Pssm-ID: 463648 [Multi-domain] Cd Length: 64 Bit Score: 80.99 E-value: 4.45e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2490940235 259 DMFLDKPTDAPIRELAHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGLFEQLFPVLVPFF 322
Cdd:pfam12627 1 GFTIEPETREAIRKLAPLLKKISPERIFEELLKLLLSGHPERGLELLRETGLLEYLFPELAAAL 64
|
|
| PRK13297 |
PRK13297 |
tRNA CCA-pyrophosphorylase; Provisional |
97-265 |
7.95e-17 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 139469 [Multi-domain] Cd Length: 364 Bit Score: 81.97 E-value: 7.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 97 AGFEAYVVGGCIRDLLLGHKPKDFD-VATNAKPEEIQKifgRQCRLIGRRFRLahIVFGRDIYEVATFRadhsnhsSDKI 175
Cdd:PRK13297 10 AGLQVYIVGGAVRDALLGLPAGDRDwVVVGATPEDMAR---RGFIPVGGDFPV--FLHPRTKEEYALAR-------TERK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 176 SKVSEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDPKHNLIfDFFDGIADLKAGKLRLIGDPvirYQEDPVRMLRAVRFM 255
Cdd:PRK13297 78 SGRGYKGFTFYTGADVTLEQDLQRRDLTVNAIARTPQGELV-DPLDGVADVRARVLRHVGEA---FAEDPVRILRLGRFA 153
|
170
....*....|
gi 2490940235 256 AKLDMFLDKP 265
Cdd:PRK13297 154 ARFGDFSIAP 163
|
|
| PRK13296 |
PRK13296 |
CCA tRNA nucleotidyltransferase; |
100-350 |
1.16e-15 |
|
CCA tRNA nucleotidyltransferase;
Pssm-ID: 106256 [Multi-domain] Cd Length: 360 Bit Score: 78.49 E-value: 1.16e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 100 EAYVVGGCIRDLLLGHKPKDFD-VATNAKPEEiqkifgrqcrLIGRRFrlAHIVFGRDIYEVATFRADHSNHSSDKISKV 178
Cdd:PRK13296 2 KFYLVGGAVRDMLLGITPKDKDwVVVGATEDE----------MLANGF--IKIAANFPVFIHPQTKQEYALARSEKKTAS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 179 SEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDpKHNLIFDFFDGIADLKAGKLRLIGDPVIryqEDPVRMLRAVRFMAKL 258
Cdd:PRK13296 70 GYHGFEVNFSKYITLEDDLKRRDLTINSIAID-QNNKVIDPFNGQADLQNRILRHTSIAFI---EDPLRVVRLARFKAQL 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 259 DMFLDKPTDAPIRELAHLLKN-----IPAARLFDESLKLLQSGQGFktYQLMRQYGLFEQLFP------VLVP---FF-- 322
Cdd:PRK13296 146 SNFNFSIAQEMLALIKELVKTgelnhLTRERLHIEFVKALNNPKIF--FTTLKELEALKIIFPniscilPLIPnksFFen 223
|
250 260
....*....|....*....|....*....
gi 2490940235 323 -TERNDSNAERMLSKALNSTDDRIrDNLR 350
Cdd:PRK13296 224 pIYKGSNINEKITLCLLKIPQQQL-DDIR 251
|
|
| PRK13298 |
PRK13298 |
tRNA CCA-pyrophosphorylase; Provisional |
100-326 |
5.47e-14 |
|
tRNA CCA-pyrophosphorylase; Provisional
Pssm-ID: 237338 [Multi-domain] Cd Length: 417 Bit Score: 73.61 E-value: 5.47e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 100 EAYVVGGCIRDLLLGHKPKDFD-VATNAKPEEIQKIFGRQcrlIGRRFRLAHIVFGRDIYEVAtfradhsnhSSDKISKV 178
Cdd:PRK13298 2 KIYLVGGAVRDSLLNLPVKDKDwVVVGGTPKILLSINFQQ---VGKDFPVFLHPETHEEYALA---------RTERKSGV 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 179 SEEGMLLRDNVYGTLREDAQRRDFTVNSLYYDPKHNLIfDFFDGIADLKAGKLRLIGDPvirYQEDPVRMLRAVRFMAK- 257
Cdd:PRK13298 70 GYTGFITDTSSDVTLEEDLIRRDLTINAIAQDENGNYI-DPFQGKKDIQLRLLRHVSES---FIEDPLRVLRVARFAALl 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2490940235 258 --LDMFLDKPTDAPIREL--AHLLKNIPAARLFDESLKLLQSGQGFKTYQLMRQYGLFEQLFPVLVPFFTERN 326
Cdd:PRK13298 146 vhLGFKIAKETMILMCIMvkKHELLYLTPERIWNETEKALKTDNPHVYFQVLYECNALKFLFPEIDFLYEKPY 218
|
|
| cca |
PRK10885 |
multifunctional CCA addition/repair protein; |
102-258 |
8.40e-14 |
|
multifunctional CCA addition/repair protein;
Pssm-ID: 182810 [Multi-domain] Cd Length: 409 Bit Score: 72.96 E-value: 8.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 102 YVVGGCIRDLLLGHKPKDFD-VATNAKPEEIQKIFGRQcrlIGRRFRlahiVFgrdiyevatfradhsNHSsdkisKVSE 180
Cdd:PRK10885 4 YLVGGAVRDALLGLPVKDRDwVVVGATPEEMLAQGYQQ---VGKDFP----VF---------------LHP-----KTHE 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490940235 181 EGMLLRD-----NVYG----------TLREDAQRRDFTVNSLYYDPKHNLIfDFFDGIADLKAGKLRLIGDPvirYQEDP 245
Cdd:PRK10885 57 EYALARTerksgRGYTgftcyaapdvTLEEDLIRRDLTINAMAQDDDGELI-DPYGGQRDLEARLLRHVSPA---FAEDP 132
|
170
....*....|...
gi 2490940235 246 VRMLRAVRFMAKL 258
Cdd:PRK10885 133 LRVLRVARFAARF 145
|
|
| PHA01806 |
PHA01806 |
hypothetical protein |
101-123 |
5.00e-03 |
|
hypothetical protein
Pssm-ID: 222838 Cd Length: 200 Bit Score: 38.32 E-value: 5.00e-03
|
| |
