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Conserved domains on  [gi|1800013500|ref|XP_032027748|]
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kininogen-1 [Hylobates moloch]

Protein Classification

CY domain-containing protein( domain architecture ID 10440427)

CY domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 266-360 3.03e-31

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 117.05  E-value: 3.03e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 266 GCPRDIPTNSPELEETLTHTIAKLNAENNaTFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKesNEELTESCETKKL 345
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTD-NYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 1800013500 346 GQSLDCNAEVYVVPW 360
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 144-236 3.01e-27

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 105.49  E-value: 3.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 144 GCVHPVSTQSPDLEPILRHGVQYFNNNTqHSSLFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKenFLFLTPDCKSLSN 223
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|...
gi 1800013500 224 GDTGECTDNAYID 236
Cdd:pfam00031  78 KWLGLCSAQVYKV 90
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-114 1.43e-22

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 92.40  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  24 EEIDCNDKDLFKAVDAALKKYNSQNqSNNQFVLYRITEATKMVSSDTFYSFKYEIKEGDCPVqSGKTWQDCDYKDaaEAA 103
Cdd:pfam00031   4 SPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKW 79

                          90
                  ....*....|.
gi 1800013500 104 TGECTATVGKR 114
Cdd:pfam00031  80 LGLCSAQVYKV 90
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 266-360 3.03e-31

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 117.05  E-value: 3.03e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 266 GCPRDIPTNSPELEETLTHTIAKLNAENNaTFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKesNEELTESCETKKL 345
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTD-NYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 1800013500 346 GQSLDCNAEVYVVPW 360
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 264-371 3.29e-30

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 114.45  E-value: 3.29e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  264 CVGCPRDIPTNSPELEETLTHTIAKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESneELTESCETK 343
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 1800013500  344 KLGQsLDCNAEVYVVPWEKKI-YPTVNCQ 371
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKIkLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 144-236 3.01e-27

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 105.49  E-value: 3.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 144 GCVHPVSTQSPDLEPILRHGVQYFNNNTqHSSLFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKenFLFLTPDCKSLSN 223
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|...
gi 1800013500 224 GDTGECTDNAYID 236
Cdd:pfam00031  78 KWLGLCSAQVYKV 90
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 266-370 1.11e-25

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 101.78  E-value: 1.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 266 GCPRDIPTNSPELEETLTHTIAKLNAENNATfYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKL 345
Cdd:cd00042     1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                          90       100
                  ....*....|....*....|....*.
gi 1800013500 346 GQSLDCNAEVYVVPWEKKI-YPTVNC 370
Cdd:cd00042    80 GKKKFCTAKVWEKPWENFKeLLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-114 1.43e-22

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 92.40  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  24 EEIDCNDKDLFKAVDAALKKYNSQNqSNNQFVLYRITEATKMVSSDTFYSFKYEIKEGDCPVqSGKTWQDCDYKDaaEAA 103
Cdd:pfam00031   4 SPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKW 79

                          90
                  ....*....|.
gi 1800013500 104 TGECTATVGKR 114
Cdd:pfam00031  80 LGLCSAQVYKV 90
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 142-249 5.58e-20

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 85.56  E-value: 5.58e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  142 CLGCVHPVSTQSPDLEPILRHGVQYFNNNTQHSSLFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKEnfLFLTPDCKSL 221
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKL--SVDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 1800013500  222 SNGDtGECTDNAY-IDTQLRIASFSQNCD 249
Cdd:smart00043  80 DQGE-KFCTAKVWeKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 144-248 1.42e-19

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 84.06  E-value: 1.42e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 144 GCVHPVSTQSPDLEPILRHGVQYFNNNTQHSSlFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLSN 223
Cdd:cd00042     1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                          90       100
                  ....*....|....*....|....*.
gi 1800013500 224 GDTGECTDNAY-IDTQLRIASFSQNC 248
Cdd:cd00042    80 GKKKFCTAKVWeKPWENFKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-127 6.65e-19

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 82.48  E-value: 6.65e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500   24 EEIDCNDKDLFKAVDAALKKYNsqNQSNNQFVLYRIT--EATKMVSSDTFYSFKYEIKEGDCPVQSGKtWQDCDYKDAAE 101
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYN--KKSNDKYELRVIKvvSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE 83

                           90       100
                   ....*....|....*....|....*..
gi 1800013500  102 aatGECTATVG-KRGSTKFSVATQTCQ 127
Cdd:smart00043  84 ---KFCTAKVWeKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-126 2.41e-09

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 55.17  E-value: 2.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  24 EEIDCNDKDLFKAVDAALKKYNSQNQSNNqFVLYRITEATKMVSSDTFYSFKYEIKEGDCPVQSGKTWQdCDYKDAAEAA 103
Cdd:cd00042     4 SDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEEGK 81

                          90       100
                  ....*....|....*....|....
gi 1800013500 104 TGECTATVGKRGSTKF-SVATQTC 126
Cdd:cd00042    82 KKFCTAKVWEKPWENFkELLSFKC 105
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 266-360 3.03e-31

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 117.05  E-value: 3.03e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 266 GCPRDIPTNSPELEETLTHTIAKLNAENNaTFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKesNEELTESCETKKL 345
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTD-NYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 1800013500 346 GQSLDCNAEVYVVPW 360
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 264-371 3.29e-30

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 114.45  E-value: 3.29e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  264 CVGCPRDIPTNSPELEETLTHTIAKLNAENNATFYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESneELTESCETK 343
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 1800013500  344 KLGQsLDCNAEVYVVPWEKKI-YPTVNCQ 371
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKIkLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 144-236 3.01e-27

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 105.49  E-value: 3.01e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 144 GCVHPVSTQSPDLEPILRHGVQYFNNNTqHSSLFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKenFLFLTPDCKSLSN 223
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|...
gi 1800013500 224 GDTGECTDNAYID 236
Cdd:pfam00031  78 KWLGLCSAQVYKV 90
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 266-370 1.11e-25

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 101.78  E-value: 1.11e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 266 GCPRDIPTNSPELEETLTHTIAKLNAENNATfYFKIDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKL 345
Cdd:cd00042     1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                          90       100
                  ....*....|....*....|....*.
gi 1800013500 346 GQSLDCNAEVYVVPWEKKI-YPTVNC 370
Cdd:cd00042    80 GKKKFCTAKVWEKPWENFKeLLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-114 1.43e-22

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 92.40  E-value: 1.43e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  24 EEIDCNDKDLFKAVDAALKKYNSQNqSNNQFVLYRITEATKMVSSDTFYSFKYEIKEGDCPVqSGKTWQDCDYKDaaEAA 103
Cdd:pfam00031   4 SPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKW 79

                          90
                  ....*....|.
gi 1800013500 104 TGECTATVGKR 114
Cdd:pfam00031  80 LGLCSAQVYKV 90
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 142-249 5.58e-20

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 85.56  E-value: 5.58e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  142 CLGCVHPVSTQSPDLEPILRHGVQYFNNNTQHSSLFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKEnfLFLTPDCKSL 221
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKL--SVDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 1800013500  222 SNGDtGECTDNAY-IDTQLRIASFSQNCD 249
Cdd:smart00043  80 DQGE-KFCTAKVWeKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 144-248 1.42e-19

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 84.06  E-value: 1.42e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500 144 GCVHPVSTQSPDLEPILRHGVQYFNNNTQHSSlFTLHEVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLSN 223
Cdd:cd00042     1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                          90       100
                  ....*....|....*....|....*.
gi 1800013500 224 GDTGECTDNAY-IDTQLRIASFSQNC 248
Cdd:cd00042    80 GKKKFCTAKVWeKPWENFKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-127 6.65e-19

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 82.48  E-value: 6.65e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500   24 EEIDCNDKDLFKAVDAALKKYNsqNQSNNQFVLYRIT--EATKMVSSDTFYSFKYEIKEGDCPVQSGKtWQDCDYKDAAE 101
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYN--KKSNDKYELRVIKvvSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE 83

                           90       100
                   ....*....|....*....|....*..
gi 1800013500  102 aatGECTATVG-KRGSTKFSVATQTCQ 127
Cdd:smart00043  84 ---KFCTAKVWeKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-126 2.41e-09

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 55.17  E-value: 2.41e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  24 EEIDCNDKDLFKAVDAALKKYNSQNQSNNqFVLYRITEATKMVSSDTFYSFKYEIKEGDCPVQSGKTWQdCDYKDAAEAA 103
Cdd:cd00042     4 SDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEEGK 81

                          90       100
                  ....*....|....*....|....
gi 1800013500 104 TGECTATVGKRGSTKF-SVATQTC 126
Cdd:cd00042    82 KKFCTAKVWEKPWENFkELLSFKC 105
Cathelicidins pfam00666
Cathelicidin; A novel protein family, showing a conserved proregion and a variable ...
 36-111 2.63e-03

Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins.


Pssm-ID: 395539  Cd Length: 101  Bit Score: 37.86  E-value: 2.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1800013500  36 AVDAALKKYNSQNQSNNqfvLYRITEATKM----VSSDTFYSFKYEIKEGDCPVQSGKTWQDCDYKDAAEAAtgECTATV 111
Cdd:pfam00666   8 AVLRAVDQFNEQSSEAN---LYRLLELDPPpqddEDPDTPKPVSFRVKETVCPRTTQQPPEQCDFKENGLVK--RCVGTV 82
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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