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Conserved domains on  [gi|1907068038|ref|XP_036019100|]
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nck-associated protein 5 isoform X15 [Mus musculus]

Protein Classification

SMC_prok_B and NCKAP5 domain-containing protein( domain architecture ID 10633646)

protein containing domains SMC_prok_B, PHA03247, and NCKAP5

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
NCKAP5 pfam15246
Nck-associated protein 5, Peripheral clock protein; NCKAP5 is short for Nck-associated protein ...
1299-1601 4.14e-134

Nck-associated protein 5, Peripheral clock protein; NCKAP5 is short for Nck-associated protein 5, which is also known as the Peripheral clock protein. NCKAP5 is a protein family, which interacts with the SH3-containing region of the adaptor protein Nck. Nck is a protein that interacts with receptor tyrosine kinases and guanine nucleotide exchange factor Sos. The role of Nck can be thought of as similar to Grb2. The role of NCKAP5 is to assist Nck with its adaptor protein role.


:

Pssm-ID: 464586  Cd Length: 309  Bit Score: 419.94  E-value: 4.14e-134
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1299 LSPSIEEKVMLCIQENVEKGQVQTKSASVEVKPRAGPSFTSWFGFRKSRLPALSSRRMEASKSKVEKKDTKLKSERKKEK 1378
Cdd:pfam15246    1 LQSTIEEKVMLGIQENVLKGQVQDKSQSVETKQKTGPSIASWFGFRKSKLPALSSRKMDVSKGKEEKKEWKGSGFGGKQL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1379 KK--------AEVQSKIENELSRGTKKADGqsPDDGLQSSESLKVSQDIYNQMKLEPRNRPSPAVCPTKDAFMTELLNRV 1450
Cdd:pfam15246   81 KSekkkekkkEELQCALEEELAYKNEVGLD--RDGRGHSKKLLKIPQDCEVQMGQEQSQLSSPYTCMTKDTFMQELLNRV 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1451 DKRASVQRESGSKGVSCRSVLEGTSQGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNEDVQEDEEDRVADTTLQ 1530
Cdd:pfam15246  159 DKKAAQQTESGSNNVSCRSVSKGSSQGSCLPSNSISTQGNHKKNSKTKADMEIPRESLIKEVAENVQEDEEDTLADSACQ 238
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907068038 1531 SHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASMASSARAQTLDREVPSS 1601
Cdd:pfam15246  239 DHFIGSGCQMRTLDSGIGTFPLPDSGNRSTGRHIPKPESSEETEPLLSLQPALPTAVPRRARTLEREVPSS 309
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
3-186 5.61e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 5.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    3 EKLIHELEEE----RHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQgspEQKKEEPAKITAYQEGL 78
Cdd:TIGR02168  690 EEKIAELEKAlaelRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI---AQLSKELTELEAEIEEL 766
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   79 PDEERKEQAALgdlhvVAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSAL---ALENENQREQYERCLDEVANQVV 155
Cdd:TIGR02168  767 EERLEEAEEEL-----AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneeAANLRERLESLERRIAATERRLE 841
                          170       180       190
                   ....*....|....*....|....*....|.
gi 1907068038  156 RALLTQKDLREECVKLKTRVFDLEQQNRALS 186
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELE 872
PHA03247 super family cl33720
large tegument protein UL36; Provisional
673-884 1.38e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  673 TPASPMGKLSQCRKAESPGSLcdvQPESHIPKHPAQVP----HIPKISNKKNWVQCPRSQTSGIQSRHLMGRSDSSEMRS 748
Cdd:PHA03247  2597 RPRAPVDDRGDPRGPAPPSPL---PPDTHAPDPPPPSPspaaNEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA 2673
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  749 NGcVSAPQTRMRSPSPPTPPGrSVSLLVRPSyDYPPLPSPAkPETQGPGDAVSPGlksPLLKGSSAPLVSSSPVmseiqk 828
Cdd:PHA03247  2674 AQ-ASSPPQRPRRRAARPTVG-SLTSLADPP-PPPPTPEPA-PHALVSATPLPPG---PAAARQASPALPAAPA------ 2740
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907068038  829 kpsvasrksafPPALPSTQAVvhtryPEHIASSPFAVTTSGPPKVSPKRGIPKPPP 884
Cdd:PHA03247  2741 -----------PPAVPAGPAT-----PGGPARPARPPTTAGPPAPAPPAAPAAGPP 2780
 
Name Accession Description Interval E-value
NCKAP5 pfam15246
Nck-associated protein 5, Peripheral clock protein; NCKAP5 is short for Nck-associated protein ...
1299-1601 4.14e-134

Nck-associated protein 5, Peripheral clock protein; NCKAP5 is short for Nck-associated protein 5, which is also known as the Peripheral clock protein. NCKAP5 is a protein family, which interacts with the SH3-containing region of the adaptor protein Nck. Nck is a protein that interacts with receptor tyrosine kinases and guanine nucleotide exchange factor Sos. The role of Nck can be thought of as similar to Grb2. The role of NCKAP5 is to assist Nck with its adaptor protein role.


Pssm-ID: 464586  Cd Length: 309  Bit Score: 419.94  E-value: 4.14e-134
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1299 LSPSIEEKVMLCIQENVEKGQVQTKSASVEVKPRAGPSFTSWFGFRKSRLPALSSRRMEASKSKVEKKDTKLKSERKKEK 1378
Cdd:pfam15246    1 LQSTIEEKVMLGIQENVLKGQVQDKSQSVETKQKTGPSIASWFGFRKSKLPALSSRKMDVSKGKEEKKEWKGSGFGGKQL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1379 KK--------AEVQSKIENELSRGTKKADGqsPDDGLQSSESLKVSQDIYNQMKLEPRNRPSPAVCPTKDAFMTELLNRV 1450
Cdd:pfam15246   81 KSekkkekkkEELQCALEEELAYKNEVGLD--RDGRGHSKKLLKIPQDCEVQMGQEQSQLSSPYTCMTKDTFMQELLNRV 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1451 DKRASVQRESGSKGVSCRSVLEGTSQGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNEDVQEDEEDRVADTTLQ 1530
Cdd:pfam15246  159 DKKAAQQTESGSNNVSCRSVSKGSSQGSCLPSNSISTQGNHKKNSKTKADMEIPRESLIKEVAENVQEDEEDTLADSACQ 238
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907068038 1531 SHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASMASSARAQTLDREVPSS 1601
Cdd:pfam15246  239 DHFIGSGCQMRTLDSGIGTFPLPDSGNRSTGRHIPKPESSEETEPLLSLQPALPTAVPRRARTLEREVPSS 309
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
3-186 5.61e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 5.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    3 EKLIHELEEE----RHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQgspEQKKEEPAKITAYQEGL 78
Cdd:TIGR02168  690 EEKIAELEKAlaelRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI---AQLSKELTELEAEIEEL 766
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   79 PDEERKEQAALgdlhvVAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSAL---ALENENQREQYERCLDEVANQVV 155
Cdd:TIGR02168  767 EERLEEAEEEL-----AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneeAANLRERLESLERRIAATERRLE 841
                          170       180       190
                   ....*....|....*....|....*....|.
gi 1907068038  156 RALLTQKDLREECVKLKTRVFDLEQQNRALS 186
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELE 872
PHA03247 PHA03247
large tegument protein UL36; Provisional
673-884 1.38e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  673 TPASPMGKLSQCRKAESPGSLcdvQPESHIPKHPAQVP----HIPKISNKKNWVQCPRSQTSGIQSRHLMGRSDSSEMRS 748
Cdd:PHA03247  2597 RPRAPVDDRGDPRGPAPPSPL---PPDTHAPDPPPPSPspaaNEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA 2673
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  749 NGcVSAPQTRMRSPSPPTPPGrSVSLLVRPSyDYPPLPSPAkPETQGPGDAVSPGlksPLLKGSSAPLVSSSPVmseiqk 828
Cdd:PHA03247  2674 AQ-ASSPPQRPRRRAARPTVG-SLTSLADPP-PPPPTPEPA-PHALVSATPLPPG---PAAARQASPALPAAPA------ 2740
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907068038  829 kpsvasrksafPPALPSTQAVvhtryPEHIASSPFAVTTSGPPKVSPKRGIPKPPP 884
Cdd:PHA03247  2741 -----------PPAVPAGPAT-----PGGPARPARPPTTAGPPAPAPPAAPAAGPP 2780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
3-185 2.18e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    3 EKLIHELEEERHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEepakitAYQEGLPDEE 82
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RLEERRRELE 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   83 RKEQAALGDLHVVAADEDSRSEH-SSVEEGKEDSRLLLKRLKALEAENSALALENENQREQYERCLDEVANQVVRALLTQ 161
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEElEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                          170       180
                   ....*....|....*....|....
gi 1907068038  162 KDLREECVKLKTRVFDLEQQNRAL 185
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERL 419
 
Name Accession Description Interval E-value
NCKAP5 pfam15246
Nck-associated protein 5, Peripheral clock protein; NCKAP5 is short for Nck-associated protein ...
1299-1601 4.14e-134

Nck-associated protein 5, Peripheral clock protein; NCKAP5 is short for Nck-associated protein 5, which is also known as the Peripheral clock protein. NCKAP5 is a protein family, which interacts with the SH3-containing region of the adaptor protein Nck. Nck is a protein that interacts with receptor tyrosine kinases and guanine nucleotide exchange factor Sos. The role of Nck can be thought of as similar to Grb2. The role of NCKAP5 is to assist Nck with its adaptor protein role.


Pssm-ID: 464586  Cd Length: 309  Bit Score: 419.94  E-value: 4.14e-134
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1299 LSPSIEEKVMLCIQENVEKGQVQTKSASVEVKPRAGPSFTSWFGFRKSRLPALSSRRMEASKSKVEKKDTKLKSERKKEK 1378
Cdd:pfam15246    1 LQSTIEEKVMLGIQENVLKGQVQDKSQSVETKQKTGPSIASWFGFRKSKLPALSSRKMDVSKGKEEKKEWKGSGFGGKQL 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1379 KK--------AEVQSKIENELSRGTKKADGqsPDDGLQSSESLKVSQDIYNQMKLEPRNRPSPAVCPTKDAFMTELLNRV 1450
Cdd:pfam15246   81 KSekkkekkkEELQCALEEELAYKNEVGLD--RDGRGHSKKLLKIPQDCEVQMGQEQSQLSSPYTCMTKDTFMQELLNRV 158
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038 1451 DKRASVQRESGSKGVSCRSVLEGTSQGSCFASGSVSTQGSQKKNIKTKVDMEKPRESLGAEVNEDVQEDEEDRVADTTLQ 1530
Cdd:pfam15246  159 DKKAAQQTESGSNNVSCRSVSKGSSQGSCLPSNSISTQGNHKKNSKTKADMEIPRESLIKEVAENVQEDEEDTLADSACQ 238
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907068038 1531 SHMIESNCQMRTLDSGIGTFPLPDSGNRSVGRYICQQDSPEDTDALLPLQPAASMASSARAQTLDREVPSS 1601
Cdd:pfam15246  239 DHFIGSGCQMRTLDSGIGTFPLPDSGNRSTGRHIPKPESSEETEPLLSLQPALPTAVPRRARTLEREVPSS 309
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
3-186 5.61e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 48.13  E-value: 5.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    3 EKLIHELEEE----RHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQgspEQKKEEPAKITAYQEGL 78
Cdd:TIGR02168  690 EEKIAELEKAlaelRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERI---AQLSKELTELEAEIEEL 766
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   79 PDEERKEQAALgdlhvVAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSAL---ALENENQREQYERCLDEVANQVV 155
Cdd:TIGR02168  767 EERLEEAEEEL-----AEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLneeAANLRERLESLERRIAATERRLE 841
                          170       180       190
                   ....*....|....*....|....*....|.
gi 1907068038  156 RALLTQKDLREECVKLKTRVFDLEQQNRALS 186
Cdd:TIGR02168  842 DLEEQIEELSEDIESLAAEIEELEELIEELE 872
PHA03247 PHA03247
large tegument protein UL36; Provisional
673-884 1.38e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.24  E-value: 1.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  673 TPASPMGKLSQCRKAESPGSLcdvQPESHIPKHPAQVP----HIPKISNKKNWVQCPRSQTSGIQSRHLMGRSDSSEMRS 748
Cdd:PHA03247  2597 RPRAPVDDRGDPRGPAPPSPL---PPDTHAPDPPPPSPspaaNEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA 2673
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  749 NGcVSAPQTRMRSPSPPTPPGrSVSLLVRPSyDYPPLPSPAkPETQGPGDAVSPGlksPLLKGSSAPLVSSSPVmseiqk 828
Cdd:PHA03247  2674 AQ-ASSPPQRPRRRAARPTVG-SLTSLADPP-PPPPTPEPA-PHALVSATPLPPG---PAAARQASPALPAAPA------ 2740
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907068038  829 kpsvasrksafPPALPSTQAVvhtryPEHIASSPFAVTTSGPPKVSPKRGIPKPPP 884
Cdd:PHA03247  2741 -----------PPAVPAGPAT-----PGGPARPARPPTTAGPPAPAPPAAPAAGPP 2780
PHA03378 PHA03378
EBNA-3B; Provisional
636-937 1.05e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 43.90  E-value: 1.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  636 GLTKIPSRGKSSPQKSKLVESMPTMLVPSSALVTPEKTPASPMgklSQCRKAESPGSLCDVQPESHIPKHPAQVPHIPki 715
Cdd:PHA03378   568 GLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPT---TQSHIPETSAPRQWPMPLRPIPMRPLRMQPIT-- 642
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  716 snkknwvqcprSQTSGIQSRHLMGRSDSSEMRSNGCVSApqtrmRSPSPPTPPGRSVSLLVRPSydypplPSPAKPETQG 795
Cdd:PHA03378   643 -----------FNVLVFPTPHQPPQVEITPYKPTWTQIG-----HIPYQPSPTGANTMLPIQWA------PGTMQPPPRA 700
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  796 PGDAVSPglkspllkgSSAPLVSSSPVMSEIQKKPSVASRKSAFPPALPSTQAVVHTRYPEHIASSPFAVTTSGPPKVSP 875
Cdd:PHA03378   701 PTPMRPP---------AAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAP 771
                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  876 KRGIPKPPPHhaLGTAHMD------TDLQTPKTCPSSCELL--EVTSCKSLSPGRKRQLSDSTVMPHRPS 937
Cdd:PHA03378   772 GAPTPQPPPQ--APPAPQQrprgapTPQPPPQAGPTSMQLMprAAPGQQGPTKQILRQLLTGGVKRGRPS 839
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
3-185 2.18e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    3 EKLIHELEEERHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSLLQSQGSPEQKKEepakitAYQEGLPDEE 82
Cdd:COG1196    242 EELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RLEERRRELE 315
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   83 RKEQAALGDLHVVAADEDSRSEH-SSVEEGKEDSRLLLKRLKALEAENSALALENENQREQYERCLDEVANQVVRALLTQ 161
Cdd:COG1196    316 ERLEELEEELAELEEELEELEEElEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395
                          170       180
                   ....*....|....*....|....
gi 1907068038  162 KDLREECVKLKTRVFDLEQQNRAL 185
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERL 419
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
753-891 2.74e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 42.39  E-value: 2.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  753 SAPQTRMRSPSPPTPPGRSvsllvrpsydyPPLPSPAKPETQGPGDAVSPglkspllkgssaPLVSSSPVMSEIQKKPSV 832
Cdd:PRK14951   369 AAEAAAPAEKKTPARPEAA-----------APAAAPVAQAAAAPAPAAAP------------AAAASAPAAPPAAAPPAP 425
                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907068038  833 ASRKSAFPPALPSTQAVVHTRYPEHIASSPFAVTTSGPPKVSPKRGIPKPPPHHALGTA 891
Cdd:PRK14951   426 VAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPA 484
PHA03247 PHA03247
large tegument protein UL36; Provisional
641-884 3.76e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 42.23  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  641 PSRGKSSPQKSKLVESMPTMLVPSSALVTPEKTPASPMGKLSQCRKAESPGSLCDVQPESHIPKHPAQVPHIPKISNKKN 720
Cdd:PHA03247  2679 PPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPA 2758
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  721 WVQC---------PRSQTSGIQSRhLMGRSDSSEMRSNGCVSAPQTRMRSPSPPTPPGRSVSLLVRPSydyPPLPSPAKP 791
Cdd:PHA03247  2759 RPPTtagppapapPAAPAAGPPRR-LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA---GPLPPPTSA 2834
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  792 ETQGPGDAVSPGLKSPLLKGSSAP--LVSSSPVMSEIQKKPSVAS----RKSAFPPALPSTQAVVHTRYPEHIASSPFAV 865
Cdd:PHA03247  2835 QPTAPPPPPGPPPPSLPLGGSVAPggDVRRRPPSRSPAAKPAAPArppvRRLARPAVSRSTESFALPPDQPERPPQPQAP 2914
                          250
                   ....*....|....*....
gi 1907068038  866 TTSGPPKVSPKRGIPKPPP 884
Cdd:PHA03247  2915 PPPQPQPQPPPPPQPQPPP 2933
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
3-254 4.36e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 4.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    3 EKLIHELEEE-RHLRLQSE--ERLREVTLESERNRIQMLGLQQQF--SRMEETVRSLLQSQgspEQKKEEPAKITAYQEG 77
Cdd:TIGR02168  192 EDILNELERQlKSLERQAEkaERYKELKAELRELELALLVLRLEElrEELEELQEELKEAE---EELEELTAELQELEEK 268
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   78 L--------PDEERKE--QAALGDL---------HVVAADEDSRSEHSSVEEGKEDSRLLLKRLKALEAENSALALENEN 138
Cdd:TIGR02168  269 LeelrlevsELEEEIEelQKELYALaneisrleqQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038  139 QREQYERC---LDEVANQVVRALLTQKDLREECVKLKTRVFDLEQQNRALSLLFQQrvrpaSDVLLQQSSRIWDKRLSID 215
Cdd:TIGR02168  349 LKEELESLeaeLEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIER-----LEARLERLEDRRERLQQEI 423
                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1907068038  216 SSLPSGFASPADELPPTRIKEshILEGLRKLQKRKVFLE 254
Cdd:TIGR02168  424 EELLKKLEEAELKELQAELEE--LEEELEELQEELERLE 460
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
6-194 8.58e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 40.91  E-value: 8.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038    6 IHELEEERHLRLQSEERLREVTLESERNRIQMLGLQQQFSRMEETVRSL---LQSQGSPEQKKEEPAKITAYQEGLPDEE 82
Cdd:COG4717     73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLeklLQLLPLYQELEALEAELAELPERLEELE 152
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907068038   83 RKEQAalgdlhVVAADEDSRSEHSSVEEGKEDsrlllkrlkaLEAENSALALENENQREQYERCLDEVANQVVRALLTQK 162
Cdd:COG4717    153 ERLEE------LRELEEELEELEAELAELQEE----------LEELLEQLSLATEEELQDLAEELEELQQRLAELEEELE 216
                          170       180       190
                   ....*....|....*....|....*....|..
gi 1907068038  163 DLREECVKLKTRVFDLEQQNRALSLlfQQRVR 194
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAAAL--EERLK 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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