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Conserved domains on  [gi|2217329721|ref|XP_047301104|]
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tetratricopeptide repeat protein 7A isoform X8 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC7_N super family cl44857
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 5-315 5.33e-133

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


The actual alignment was detected with superfamily member pfam19440:

Pssm-ID: 466084  Cd Length: 386  Bit Score: 399.54  E-value: 5.33e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721   5 EKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLSEAFVIK 84
Cdd:pfam19440  71 EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIK 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721  85 GLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLK-GCHPLDYELTYFLEAALQSAYVKN 163
Cdd:pfam19440 151 GLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNTQNRSPKpGPPSQEQELGFFLETALQRAYVLY 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 164 LKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEES-SFATQA---LRKP 239
Cdd:pfam19440 231 FKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPLkGTNTKNytpSRKP 310

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 240 HLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECL 315
Cdd:pfam19440 311 RVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 622-761 4.82e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.06  E-value: 4.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 622 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 701
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 702 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL 761
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
Spy super family cl27809
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 372-541 7.34e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG3914:

Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 372 GSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPSDPQVILYVS 451
Cdd:COG3914    42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 452 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEA 531
Cdd:COG3914   120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                         170
                  ....*....|
gi 2217329721 532 LVTCRQVLRL 541
Cdd:COG3914   200 IAAYRRALEL 209
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 290-384 9.39e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 9.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 290 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 369
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                          90
                  ....*....|....*
gi 2217329721 370 CIGSLRWLEEAEHFA 384
Cdd:COG4783   116 YRALGRPDEAIAALE 130
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 5-315 5.33e-133

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 399.54  E-value: 5.33e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721   5 EKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLSEAFVIK 84
Cdd:pfam19440  71 EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIK 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721  85 GLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLK-GCHPLDYELTYFLEAALQSAYVKN 163
Cdd:pfam19440 151 GLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNTQNRSPKpGPPSQEQELGFFLETALQRAYVLY 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 164 LKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEES-SFATQA---LRKP 239
Cdd:pfam19440 231 FKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPLkGTNTKNytpSRKP 310

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 240 HLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECL 315
Cdd:pfam19440 311 RVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 622-761 4.82e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.06  E-value: 4.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 622 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 701
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 702 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL 761
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 516-767 5.62e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 56.15  E-value: 5.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 516 FTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGlTMKKQSGMHLTLPDAHdADSGSRRASSIAAS 595
Cdd:TIGR00990 242 FAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLEDSNELDEE-TGNGQLQLGLKSPESK-ADESYEEAARAFEK 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 596 RLE-------EAMS-ELTMPSSVLKQGP----------MQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSH 657
Cdd:TIGR00990 320 ALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDP 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 658 SVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 737
Cdd:TIGR00990 400 DIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLD 479

                         250       260       270
                  ....*....|....*....|....*....|
gi 2217329721 738 QGQNEAAVDCFLTALELEASSPVLPFSIIP 767
Cdd:TIGR00990 480 QNKFDEAIEKFDTAIELEKETKPMYMNVLP 509
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 372-541 7.34e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 372 GSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPSDPQVILYVS 451
Cdd:COG3914    42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 452 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEA 531
Cdd:COG3914   120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                         170
                  ....*....|
gi 2217329721 532 LVTCRQVLRL 541
Cdd:COG3914   200 IAAYRRALEL 209
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 418-760 1.03e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 418 LKSKQDElhrKALQTLERAQQLAPSDPQViLYVSLQLALVR-QISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQH 496
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLA-HYLKALVDFQKkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 497 ALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGG---------------LEKDGSFG 561
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGeaylalgdfekaaeyLAKATELD 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 562 EGLTMKK-QSGM-HLTLPDAHDADsgsrrASSIAASRLEEAM--SELTMPSSVLKQGPM------------------QLW 619
Cdd:TIGR02917 394 PENAAARtQLGIsKLSQGDPSEAI-----ADLETAAQLDPELgrADLLLILSYLRSGQFdkalaaakklekkqpdnaSLH 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 620 TTLEQIWLQAAELFMEQQHLKEAgfcIQEAAGLFPTSHSVLymrgRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGL 699
Cdd:TIGR02917 469 NLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAAANLA----RIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 700 MLSRLGHKS---------------------------LAQK-------VLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAV 745
Cdd:TIGR02917 542 LYLRTGNEEeavawlekaaelnpqeiepalalaqyyLGKGqlkkalaILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                         410
                  ....*....|....*
gi 2217329721 746 DCFLTALELEASSPV 760
Cdd:TIGR02917 622 SSFKKLLALQPDSAL 636
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 290-384 9.39e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 9.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 290 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 369
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                          90
                  ....*....|....*
gi 2217329721 370 CIGSLRWLEEAEHFA 384
Cdd:COG4783   116 YRALGRPDEAIAALE 130
TPR_11 pfam13414
TPR repeat;
670-705 1.83e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.83e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2217329721 670 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 705
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
 
Name Accession Description Interval E-value
TTC7_N pfam19440
Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a ...
 5-315 5.33e-133

Tetratricopeptide repeat protein 7 N-terminal; This is the N-terminal domain of TTC7, a protein that forms the regulatory subunit of the PI4KIIIalpha complex (also known as PI4KA). This complex is composed of PI4KIIIalpha, TTC7 and FAM126A and catalyzes the first step in plasma membrane phosphoinositide synthesis. This TTC7 N-terminal domain contains basic residues suitable for interaction with the acidic inner leaflet of the plasma membrane and is required for localising the active site near its substrate. TTC7 acts as a bridge between PI4KA and EFR3B-FAM126A, via direct interactions. ERF3B is not part of the complex but contributes to its recruitment to the membrane.


Pssm-ID: 466084  Cd Length: 386  Bit Score: 399.54  E-value: 5.33e-133
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721   5 EKNEPKMSEAKNYLSSILNHGRLSPQYMCEAMLILGKLHYVEGSYRDAISMYARAGIDDMSMENKPLYQMRLLSEAFVIK 84
Cdd:pfam19440  71 EKNQPKLSEAKKHLTSALDRGNLKPEFLQEAHLLLAKLNYVEGDYREALNMYARAGLDDLTLKELPVYRLRLLAEAYAIK 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721  85 GLSLERLPNSIASRFRLTEREEEVITCFERASWIAQVFLQELEKTTNNSTSRHLK-GCHPLDYELTYFLEAALQSAYVKN 163
Cdd:pfam19440 151 GLCLEKQAVSSSSRVRLAEREEEMITCYEKAGDIALLYLQELERINSNTQNRSPKpGPPSQEQELGFFLETALQRAYVLY 230

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 164 LKKGNIVKGMRELREVLRTVETKATQNFKVMAAKHLAGVLLHSLSEECYWSPLSHPLPEFMGKEES-SFATQA---LRKP 239
Cdd:pfam19440 231 FKKGNLARGVGRYREILRAVETRTTQNLRMTIARQLAEVLLRGVCEQSYWNPLEDPPPQSLLDEPLkGTNTKNytpSRKP 310

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 240 HLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRVPEQEEDRTVSLQNAAAIYDLLSITLGRRGQYVMLSECL 315
Cdd:pfam19440 311 RVYSGENIFCPQDNVEEALLLLLISESMANRDAVLSRSPEHREARIISLQNATAVYDLLTIAMGRRGQYEMLSECL 386
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 622-761 4.82e-20

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 95.06  E-value: 4.82e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 622 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 701
Cdd:COG3914    77 LAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEAL 156

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 702 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL 761
Cdd:COG3914   157 RRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADA 216
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
624-755 1.76e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 82.75  E-value: 1.76e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 703
Cdd:COG0457     9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2217329721 704 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 755
Cdd:COG0457    89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 624-756 2.97e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 73.30  E-value: 2.97e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 703
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217329721 704 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEA 756
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 623-761 4.83e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.22  E-value: 4.83e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 623 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 702
Cdd:COG2956   110 AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYL 189

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2217329721 703 RLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL 761
Cdd:COG2956   190 EQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLL 248
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
624-756 6.75e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.96  E-value: 6.75e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 703
Cdd:COG0457    43 EALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLE 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217329721 704 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEA 756
Cdd:COG0457   123 LGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAAL 175
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
652-759 7.70e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 71.96  E-value: 7.70e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 652 LFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGL 731
Cdd:COG0457     3 LDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNL 82

                          90       100
                  ....*....|....*....|....*...
gi 2217329721 732 GEVLQAQGQNEAAVDCFLTALELEASSP 759
Cdd:COG0457    83 GLALQALGRYEEALEDYDKALELDPDDA 110
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 622-759 9.10e-14

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 75.03  E-value: 9.10e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 622 LEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLML 701
Cdd:COG3914    43 LALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLL 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2217329721 702 SRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 759
Cdd:COG3914   123 LALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA 180
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 623-755 1.53e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 1.53e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 623 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 702
Cdd:COG2956    76 AEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYL 155

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2217329721 703 RLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 755
Cdd:COG2956   156 EQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQD 208
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 658-759 1.12e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.98  E-value: 1.12e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 658 SVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 737
Cdd:COG4783     5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                          90       100
                  ....*....|....*....|..
gi 2217329721 738 QGQNEAAVDCFLTALELEASSP 759
Cdd:COG4783    85 AGDYDEALALLEKALKLDPEHP 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 623-753 3.90e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 3.90e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 623 EQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLS 702
Cdd:COG2956   144 AHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYE 223

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2217329721 703 RLGHKSLAQKVLRDAVERQSTcHEAWQGLGEVLQAQGQNEAAVDCFLTALE 753
Cdd:COG2956   224 KLGDPEEALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQLR 273
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 641-754 2.66e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 2.66e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 641 EAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVER 720
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90       100       110
                  ....*....|....*....|....*....|....
gi 2217329721 721 QSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 754
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 670-755 3.76e-11

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 61.90  E-value: 3.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 670 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFL 749
Cdd:COG5010    67 LGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQ 146


                  ....*.
gi 2217329721 750 TALELE 755
Cdd:COG5010   147 RALGTS 152
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 626-754 1.15e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.21  E-value: 1.15e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 626 WLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 705
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2217329721 706 HKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 754
Cdd:COG2956    91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKL 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 624-759 4.96e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 61.28  E-value: 4.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 703
Cdd:COG2956    43 EAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQ 122

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 704 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 759
Cdd:COG2956   123 EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCA 178
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 624-765 8.18e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 62.32  E-value: 8.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 703
Cdd:COG3914   113 EALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQD 192

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2217329721 704 LGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSPVL-PFSI 765
Cdd:COG3914   193 LGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELsPFAL 255
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
670-757 8.70e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.33  E-value: 8.70e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 670 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKvLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFL 749
Cdd:COG3063     5 LGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLE 83


                  ....*...
gi 2217329721 750 TALELEAS 757
Cdd:COG3063    84 RALELDPS 91
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 661-759 3.66e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 3.66e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 661 YMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQ 740
Cdd:COG2956    12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                          90
                  ....*....|....*....
gi 2217329721 741 NEAAVDCFLTALELEASSP 759
Cdd:COG2956    92 LDRAEELLEKLLELDPDDA 110
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 624-720 7.13e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 54.63  E-value: 7.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSR 703
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQ 97

                          90
                  ....*....|....*..
gi 2217329721 704 LGHKSLAQKVLRDAVER 720
Cdd:COG4235    98 QGDYAEAIAAWQKLLAL 114
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 516-767 5.62e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 56.15  E-value: 5.62e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 516 FTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGGLEKDGSFGEGlTMKKQSGMHLTLPDAHdADSGSRRASSIAAS 595
Cdd:TIGR00990 242 FAESKAKEILETKPENLPSVTFVGNYLQSFRPKPRPAGLEDSNELDEE-TGNGQLQLGLKSPESK-ADESYEEAARAFEK 319

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 596 RLE-------EAMS-ELTMPSSVLKQGP----------MQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSH 657
Cdd:TIGR00990 320 ALDlgklgekEAIAlNLRGTFKCLKGKHlealadlsksIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDP 399

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 658 SVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQA 737
Cdd:TIGR00990 400 DIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLLD 479

                         250       260       270
                  ....*....|....*....|....*....|
gi 2217329721 738 QGQNEAAVDCFLTALELEASSPVLPFSIIP 767
Cdd:TIGR00990 480 QNKFDEAIEKFDTAIELEKETKPMYMNVLP 509
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
632-721 1.41e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.78  E-value: 1.41e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 632 LFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQlYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQ 711
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                          90
                  ....*....|
gi 2217329721 712 KVLRDAVERQ 721
Cdd:COG3063    80 AYLERALELD 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 372-541 7.34e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 52.69  E-value: 7.34e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 372 GSLRWLEEAEHFAMMVISLGEEAGEFLPKGYLALGLTYSLQATDATLKSKQDelHRKALQTLERAQQLAPSDPQVILYVS 451
Cdd:COG3914    42 GLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGR--YEEALALYRRALALNPDNAEALFNLG 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 452 LQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEA 531
Cdd:COG3914   120 NLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEA 199

                         170
                  ....*....|
gi 2217329721 532 LVTCRQVLRL 541
Cdd:COG3914   200 IAAYRRALEL 209
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
684-755 1.74e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.01  E-value: 1.74e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2217329721 684 LTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELE 755
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELD 72
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
617-753 5.65e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 48.37  E-value: 5.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 617 QLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHS 696
Cdd:COG4785    67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLN 146

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217329721 697 LGLMLSRLGHKSLAQKVLRDAVERQSTCHEA--WQGL------------------GEVLQAQGQNEAAVDCFLTALE 753
Cdd:COG4785   147 RGIALYYLGRYELAIADLEKALELDPNDPERalWLYLaerkldpekalallledwATAYLLQGDTEEARELFKLALA 223
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 304-540 9.77e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.19  E-value: 9.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 304 RRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWlEEAEHF 383
Cdd:COG2956    54 RRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDW-EKAIEV 132

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 384 AMMVISLGEEAGEFlpkgYLALGLTYslqatdatLKSKQDElhrKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSA 463
Cdd:COG2956   133 LERLLKLGPENAHA----YCELAELY--------LEQGDYD---EAIEALEKALKLDPDCARALLLLAELYLEQGDYEEA 197

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217329721 464 MEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENfNLMFTKVKLEQVLKGPEEALVTCRQVLR 540
Cdd:COG2956   198 IAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQLR 273
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
660-759 2.70e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 46.06  E-value: 2.70e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 660 LYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQG 739
Cdd:COG4785    76 YYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG 155

                          90       100
                  ....*....|....*....|
gi 2217329721 740 QNEAAVDCFLTALELEASSP 759
Cdd:COG4785   156 RYELAIADLEKALELDPNDP 175
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 675-759 4.68e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 4.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 675 EAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALEL 754
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80


                  ....*
gi 2217329721 755 EASSP 759
Cdd:COG4235    81 DPDNP 85
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 624-690 6.61e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 6.61e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDG 690
Cdd:COG4235    52 DALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 329-541 8.41e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.11  E-value: 8.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 329 WYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWlEEAEHFAMMVISLGEEAgeflPKGYLALGLT 408
Cdd:COG2956    11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEY-DRAIRIHQKLLERDPDR----AEALLELAQD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 409 Y--------------SLQATDATLKSKQDEL---------HRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAME 465
Cdd:COG2956    86 YlkaglldraeelleKLLELDPDDAEALRLLaeiyeqegdWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 466 QLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRL 541
Cdd:COG2956   166 ALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALEL 241
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 418-760 1.03e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.84  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 418 LKSKQDElhrKALQTLERAQQLAPSDPQViLYVSLQLALVR-QISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQH 496
Cdd:TIGR02917 238 IEAGEFE---EAEKHADALLKKAPNSPLA-HYLKALVDFQKkNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQ 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 497 ALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLWQTLYSFSQLGG---------------LEKDGSFG 561
Cdd:TIGR02917 314 AYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGeaylalgdfekaaeyLAKATELD 393

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 562 EGLTMKK-QSGM-HLTLPDAHDADsgsrrASSIAASRLEEAM--SELTMPSSVLKQGPM------------------QLW 619
Cdd:TIGR02917 394 PENAAARtQLGIsKLSQGDPSEAI-----ADLETAAQLDPELgrADLLLILSYLRSGQFdkalaaakklekkqpdnaSLH 468

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 620 TTLEQIWLQAAELFMEQQHLKEAgfcIQEAAGLFPTSHSVLymrgRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGL 699
Cdd:TIGR02917 469 NLLGAIYLGKGDLAKAREAFEKA---LSIEPDFFPAAANLA----RIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAG 541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 700 MLSRLGHKS---------------------------LAQK-------VLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAV 745
Cdd:TIGR02917 542 LYLRTGNEEeavawlekaaelnpqeiepalalaqyyLGKGqlkkalaILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAV 621

                         410
                  ....*....|....*
gi 2217329721 746 DCFLTALELEASSPV 760
Cdd:TIGR02917 622 SSFKKLLALQPDSAL 636
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 659-720 2.56e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 41.13  E-value: 2.56e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2217329721 659 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRI---MHSLGLMLSRLGHKSLAQKVLRDAVER 720
Cdd:COG1729    32 ALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLELGDYDKARATLEELIKK 96
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 691-759 3.25e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.33  E-value: 3.25e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2217329721 691 VRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAVDCFLTALELEASSP 759
Cdd:COG4783     4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEP 72
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 304-763 4.36e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 4.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 304 RRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEeaehf 383
Cdd:TIGR02917 273 QKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDE----- 347

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 384 AMMVISLGEEAGEFLPKGYLALGLTYsLQATDATlkskqdelhrKALQTLERAQQLAPSDPQVilyvSLQLALVR----Q 459
Cdd:TIGR02917 348 AIATLSPALGLDPDDPAALSLLGEAY-LALGDFE----------KAAEYLAKATELDPENAAA----RTQLGISKlsqgD 412

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 460 ISSAMEQLQEALKVrkDDAHALHLLALLFSAQKHHQ--HALDVVNMAITEHPEN---FNLMFTKVKLEQVLKGPEEALvt 534
Cdd:TIGR02917 413 PSEAIADLETAAQL--DPELGRADLLLILSYLRSGQfdKALAAAKKLEKKQPDNaslHNLLGAIYLGKGDLAKAREAF-- 488

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 535 cRQVLRLWQTlySFSQLGGLEKdgsfgegLTMKKQSgmhltLPDAHD-------ADSGSRRASsIAASRLEEAMSELTMP 607
Cdd:TIGR02917 489 -EKALSIEPD--FFPAAANLAR-------IDIQEGN-----PDDAIQrfekvltIDPKNLRAI-LALAGLYLRTGNEEEA 552

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 608 SSVLKQgPMQLWTTLEQIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVN 687
Cdd:TIGR02917 553 VAWLEK-AAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQ 631

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 688 PDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAvdcFLTALELEASSPVLPF 763
Cdd:TIGR02917 632 PDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESA---KKIAKSLQKQHPKAAL 704
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 627-720 4.75e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 4.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 627 LQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGH 706
Cdd:TIGR02917 163 LGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGE 242

                          90
                  ....*....|....
gi 2217329721 707 KSLAQKVLRDAVER 720
Cdd:TIGR02917 243 FEEAEKHADALLKK 256
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 290-384 9.39e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 9.39e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 290 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 369
Cdd:COG4783    36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                          90
                  ....*....|....*
gi 2217329721 370 CIGSLRWLEEAEHFA 384
Cdd:COG4783   116 YRALGRPDEAIAALE 130
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 659-754 1.32e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 659 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQ 738
Cdd:TIGR02917 127 LLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSL 206

                          90
                  ....*....|....*.
gi 2217329721 739 GQNEAAVDCFLTALEL 754
Cdd:TIGR02917 207 GNIELALAAYRKAIAL 222
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 426-541 1.32e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.79  E-value: 1.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 426 HRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAI 505
Cdd:COG4783    20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2217329721 506 TEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRL 541
Cdd:COG4783   100 KLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 290-383 1.69e-03

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 290 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 369
Cdd:COG3914   110 DNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNA 189

                          90
                  ....*....|....
gi 2217329721 370 CIGSLRWLEEAEHF 383
Cdd:COG3914   190 LQDLGRLEEAIAAY 203
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 666-760 1.81e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 1.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 666 LAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQGLGEVLQAQGQNEAAV 745
Cdd:COG5010    29 AALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAK 108

                          90
                  ....*....|....*
gi 2217329721 746 DCFLTALELEASSPV 760
Cdd:COG5010   109 EYYEKALALSPDNPN 123
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 625-754 1.82e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.05  E-value: 1.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 625 IWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMrGRLAEvkGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRL 704
Cdd:COG3071   195 LAAAYARALIALGDHDEAERLLREALKRQWDPRLVRLY-GRLQG--GDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRN 271

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217329721 705 GHKSLAQKVLRDAVERQSTChEAWQGLGEVLQAQGQNEAAVDCFLTALEL 754
Cdd:COG3071   272 QLWGKAREYLEAALALRPSA-EAYAELARLLEQLGDPEEAAEHYRKALAL 320
TPR_11 pfam13414
TPR repeat;
670-705 1.83e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.83e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2217329721 670 KGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLG 705
Cdd:pfam13414   7 QGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 399-523 3.42e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 3.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 399 PKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDA 478
Cdd:COG4235    17 AEGWLLLGRAYLRL-----------GRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2217329721 479 HALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQ 523
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAE 130
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 659-689 4.64e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.19  E-value: 4.64e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2217329721 659 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 689
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
290-499 4.71e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.60  E-value: 4.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 290 NAAAIYDLLSITLGRRGQYVMLSECLERAMKFAFGEFHLWYQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKV 369
Cdd:COG0457     6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 370 CIgSLRWLEEAEHFAMMVISLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPSDPQVILY 449
Cdd:COG0457    86 LQ-ALGRYEEALEDYDKALELDPD----DAEALYNLGLALLEL-----------GRYDEAIEAYERALELDPDDADALYN 149

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 2217329721 450 VSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALD 499
Cdd:COG0457   150 LGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLAL 199
TPR_1 pfam00515
Tetratricopeptide repeat;
659-689 5.08e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.09  E-value: 5.08e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2217329721 659 VLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 689
Cdd:pfam00515   3 ALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
377-540 5.34e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 5.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 377 LEEAEHFAMMVISLGEEagefLPKGYLALGLTYSLQatdatlkskqdELHRKALQTLERAQQLAPSDPQVILYVSLQLAL 456
Cdd:COG0457    24 YEEAIEDYEKALELDPD----DAEALYNLGLAYLRL-----------GRYEEALADYEQALELDPDDAEALNNLGLALQA 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 457 VRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCR 536
Cdd:COG0457    89 LGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLE 168


                  ....
gi 2217329721 537 QVLR 540
Cdd:COG0457   169 KLEA 172
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 330-755 5.72e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.07  E-value: 5.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 330 YQVALSMVACGKSAYAVSLLRECVKLRPSDPTVPLMAAKVCIGSLRWLEEAEHFammvislgeEAGEFLPKGYLALGLTY 409
Cdd:TIGR02917  60 FLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQGKFQQVLDEL---------PGKTLLDDEGAAELLAL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 410 slqATDATLKSKQDElhrKALQTLERAQQLAPSDpqviLYVSLQLAlvrQISSAMEQLQEALKvrkddahalhllallfs 489
Cdd:TIGR02917 131 ---RGLAYLGLGQLE---LAQKSYEQALAIDPRS----LYAKLGLA---QLALAENRFDEARA----------------- 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 490 aqkhhqhaldVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLwqtlysfsqlgglekdgsfgegltmkkq 569
Cdd:TIGR02917 181 ----------LIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIAL---------------------------- 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 570 sgmHLTLPDAHDADSGSRrassIAASRLEEAMSELTmpsSVLKQGPMQLWTTleqiWLQAAELFMEQQHlKEAGFCIQEA 649
Cdd:TIGR02917 223 ---RPNNIAVLLALATIL----IEAGEFEEAEKHAD---ALLKKAPNSPLAH----YLKALVDFQKKNY-EDARETLQDA 287

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 650 AGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLAQKVLRDAVERQSTCHEAWQ 729
Cdd:TIGR02917 288 LKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALS 367

                         410       420
                  ....*....|....*....|....*.
gi 2217329721 730 GLGEVLQAQGQNEAAVDCFLTALELE 755
Cdd:TIGR02917 368 LLGEAYLALGDFEKAAEYLAKATELD 393
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 624-689 8.58e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 8.58e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 624 QIWLQAAELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 689
Cdd:COG4783    73 EARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
624-689 8.61e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 8.61e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2217329721 624 QIWLQAAELFMEQQHLKEAgFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPD 689
Cdd:COG3063    27 DALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPS 91
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 428-511 9.44e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.09  E-value: 9.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 428 KALQTLERAQQLAPSDPQVILYVSLQLALVRQISSAMEQLQEALKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITE 507
Cdd:COG4783    56 EAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135


                  ....
gi 2217329721 508 HPEN 511
Cdd:COG4783   136 DPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
471-721 9.64e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 38.45  E-value: 9.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 471 LKVRKDDAHALHLLALLFSAQKHHQHALDVVNMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQVLRLwqtlysfsq 550
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL--------- 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 551 lgglekdgsfgegltmkkqsgmhltlpDAHDAdsgsrrassiaasrleeamseltmpssvlkqgpmqlwttleQIWLQAA 630
Cdd:COG0457    72 ---------------------------DPDDA-----------------------------------------EALNNLG 83

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2217329721 631 ELFMEQQHLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGNLEEAKQLYKEALTVNPDGVRIMHSLGLMLSRLGHKSLA 710
Cdd:COG0457    84 LALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEA 163

                         250
                  ....*....|.
gi 2217329721 711 QKVLRDAVERQ 721
Cdd:COG0457   164 LELLEKLEAAA 174
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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