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Conserved domains on  [gi|270267605|ref|YP_003331287|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Bathytroctes macrolepis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 5.42e-82

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 239.66  E-value: 5.42e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAGYVGAYLVGVVLAAGWFWGGWYESSWVVVDEFKEFFVLRGDSSGVALMYSFGGGMLVVCAWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 270267605 161 LTRGLSRGTLRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 5.42e-82

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 239.66  E-value: 5.42e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAGYVGAYLVGVVLAAGWFWGGWYESSWVVVDEFKEFFVLRGDSSGVALMYSFGGGMLVVCAWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 270267605 161 LTRGLSRGTLRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
25-139 4.77e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 46.73  E-value: 4.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   25 PYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPESWgdRSVAGYVGAYLVGVVLAAGW 104
Cdd:pfam00499   9 PVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEK--LRSGLPLAALLLGLLLLALL 86

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 270267605  105 FWGGWYESSWVVVDEFKEFFVlRGDSSGVALMYSF 139
Cdd:pfam00499  87 LLVLLSASLTPAAAAAAPDVG-NIEAIGELLFTDY 120
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 5.42e-82

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 239.66  E-value: 5.42e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAGYVGAYLVGVVLAAGWFWGGWYESSWVVVDEFKEFFVLRGDSSGVALMYSFGGGMLVVCAWVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 270267605 161 LTRGLSRGTLRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 6.50e-47

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 150.77  E-value: 6.50e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAGYVGAYLVGVVLaaGW-FWGGWYESSWVVVDEFKEFFVLRGDSSGVALMYSFGGGMLVVCAWVLLLTLFVVL 159
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIV--GYiLFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVL 158

                        170
                 ....*....|....
gi 270267605 160 ELTRGLSRGTLRAV 173
Cdd:MTH00065 159 EVTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 9.54e-38

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 127.56  E-value: 9.54e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAGYVGAYLVGVVLAAGWFWGGW-YESSWVVVDEFKEFFVLRGDSSGVALMYSFGGGMLVVCAWVLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 270267605 160 ELTRGLSRGTLRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 2.21e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 105.84  E-value: 2.21e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAGYVGAYLVGVVLAAGWFWGGWYESSWVVVDEFKEFFVlrgdsSGVALMYSFGGGMLVVCAWVLLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 270267605 161 LTRGLSRGTLRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-149 1.15e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 99.11  E-value: 1.15e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   1 MTYLVSLFLLGLVVGLVAVASNPAPYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605  81 SWGDRSVAgyVGAYLVGVVLAAGWFwgGWYESS--------------WVVVDEfKEFFVLRGDSSGVALMYSFGGGMLVV 146
Cdd:MTH00109  82 TWVSNKVV--LGALLLGLLMELLLV--LYVLKDdevevvfnfnglgdWVIYDT-GGSGFFSEDAMGVAALYSYGTWLVVV 156


                 ...
gi 270267605 147 CAW 149
Cdd:MTH00109 157 TGW 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 25-79 7.93e-13

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 62.62  E-value: 7.93e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 270267605  25 PYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFP 79
Cdd:MTH00045  23 PYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
25-139 4.77e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 46.73  E-value: 4.77e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270267605   25 PYFAALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALAAEPFPESWgdRSVAGYVGAYLVGVVLAAGW 104
Cdd:pfam00499   9 PVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEK--LRSGLPLAALLLGLLLLALL 86

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 270267605  105 FWGGWYESSWVVVDEFKEFFVlRGDSSGVALMYSF 139
Cdd:pfam00499  87 LLVLLSASLTPAAAAAAPDVG-NIEAIGELLFTDY 120
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 29-74 6.47e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 38.33  E-value: 6.47e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 270267605  29 ALGLVVAAGVGCGVLAAHGGAFLSLVLFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00152  27 GLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 50-74 8.75e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 37.86  E-value: 8.75e-04
                         10        20
                 ....*....|....*....|....*
gi 270267605  50 FLSLVLFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00166  47 WFSYILFLIFLGGMLVLFIYITSLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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