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Conserved domains on  [gi|295065582|ref|YP_003587383|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Nomascus siki]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-344 1.38e-160

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 452.76  E-value: 1.38e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKWQFENT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....
gi 295065582 321 KPTLLLPTLTVLTTLLLPIAPLMS 344
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLS 344
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-344 1.38e-160

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 452.76  E-value: 1.38e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKWQFENT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....
gi 295065582 321 KPTLLLPTLTVLTTLLLPIAPLMS 344
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLS 344
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-278 6.17e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.22  E-value: 6.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   23 SSHWFLTWVGLEMNMLAFIPILT-KKTNPRSTEAAIKYFLVQATASMILMMAI-----------LSNNLLSGQWTMTSTT 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGIslmynytgtlsFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   91 NQYSSLMILTALAMKLGMAPFHFWVPEVTQGT-TLTSGLLLLTWQKLAPISIM-----YQIFPVVNTNILLTFSTLSIMV 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  165 GSWGGLNQTQLRKILAYSSITHMGWMMAIL----PYNPNITIFNLTIYIVLTTTAFL-ALNLNSSTTTLLLSRSWNKLTW 239
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 295065582  240 LLPLIPSTLLSLGGLPP----LSGFLPKWLVIEELTKNGSLVI 278
Cdd:pfam00361 241 TMPILALVFLVAMLSLAglppTAGFLGKFLILAAAVAASWIFL 283
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 15-221 9.50e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.71  E-value: 9.50e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  15 AGTLIAASSSHWFLTWVGLEMNMLAFIpILT--KKTNPRSTEAAIKYFLVQATASMILMMAI-----LSNNLLSGQWTMT 87
Cdd:COG1007  113 LGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGIsllygATGSLNLAGIAAA 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  88 STTNQYSSL-------MILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVN-------TNI 153
Cdd:COG1007  192 LAAGGANSPllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFpglaadwQLL 271

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 295065582 154 LLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM-AILPYNPNI---TIFNLTIYIVLTTTAFLALNL 221
Cdd:COG1007  272 LAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlGLAAGTPLGvsaALFYLLAYLFMNLGAFAVILL 343
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-297 1.59e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 86.16  E-value: 1.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582    7 PIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAF-IPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLLSGQWT 85
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   86 MTSTTNQYSSLM------------ILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIF------- 146
Cdd:TIGR01770 185 FEDLLLFLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  147 PVVNTNILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTT-------TAFLAL 219
Cdd:TIGR01770 265 SEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYAlmslgafGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  220 NLNSSTTTLLLSrSWNKLTWLLPLIPSTLLSLGGLPP----LSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTR 295
Cdd:TIGR01770 345 RSYKDEWIEYIS-DFAGLFKTNPILAILILIFMFSLAgippLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 295065582  296 LI 297
Cdd:TIGR01770 424 VV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-344 1.38e-160

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 452.76  E-value: 1.38e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKWQFENT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....
gi 295065582 321 KPTLLLPTLTVLTTLLLPIAPLMS 344
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLS 344
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-321 2.31e-103

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 307.52  E-value: 2.31e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKWQFENT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320


                 .
gi 295065582 321 K 321
Cdd:MTH00112 321 K 321
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-321 3.43e-97

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 291.71  E-value: 3.43e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVvNTNILLTFSTL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNK---L 237
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKapaL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 238 TWLLPLI--------PSTllslgglpplsGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSN 309
Cdd:MTH00135 240 TALTPLIllslgglpPLT-----------GFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTL 308

                        330
                 ....*....|..
gi 295065582 310 NVKMKWQFENTK 321
Cdd:MTH00135 309 NGTTPWRLPSTQ 320
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-321 3.34e-96

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 289.13  E-value: 3.34e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKWQFENT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNK 320


                 .
gi 295065582 321 K 321
Cdd:MTH00070 321 T 321
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-315 3.40e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 240.64  E-value: 3.40e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKW 315
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-307 6.77e-77

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 239.83  E-value: 6.77e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLL 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPT 307
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-321 2.25e-51

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 173.47  E-value: 2.25e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   1 MNPLAQPIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLl 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 sgqwtMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFpvvNTNILLTFSTL 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLI---NNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 161 SIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWL 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 241 LPLIPSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYStsitlFPTSNNVKMKWQFENT 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYS-----SLMLNYNKNKWNLKKK 307


                 .
gi 295065582 321 K 321
Cdd:MTH00160 308 K 308
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-315 1.46e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 160.82  E-value: 1.46e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  13 VFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLLSGQWtmtsttnq 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSW-------- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  93 YSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNT-NILLTFSTLSIMVGSWGGLN 171
Cdd:MTH00144  85 FSMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 172 QTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWLLpLIPSTLLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGL-SIISLLLSL 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295065582 252 GGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYSTSITLFPTSNNVKMKW 315
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 10-312 2.78e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 157.63  E-value: 2.78e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  10 YSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAilsnnlLSGQWTMTST 89
Cdd:MTH00011  12 SSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLG------MTMMWSFPSL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  90 TNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVNTNILLTFSTLSIMVGSWGG 169
Cdd:MTH00011  86 LKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 170 LNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALN----LNSSTTTLLLSRSWNKLTWLLPLIP 245
Cdd:MTH00011 166 MNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAylnaFSTKFNSKISSMSQTTSMSLFIMLL 245

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295065582 246 StllsLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYStSITLFPTSNNVK 312
Cdd:MTH00011 246 S----LGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLK 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-300 8.42e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 148.28  E-value: 8.42e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   8 IIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMM---AILSNNLLSgqw 84
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMggsLSFSNLYLS--- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  85 tmtsttnQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMyqIFPVVNTNILLTFSTLSIMV 164
Cdd:MTH00197  79 -------LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL--AFNSSSFMGLLICSVLSSLI 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 165 GSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTTTAFLALNLNSSTTTLLLSRSWNKLTWLLPLI 244
Cdd:MTH00197 150 GGIGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFL 229

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 295065582 245 PSTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIYST 300
Cdd:MTH00197 230 GLSFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKS 285
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 7-316 3.83e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 96.62  E-value: 3.83e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   7 PIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLA-FIPILTKKTNPRSTEAAIKYFLVQATASMILM------------MA 73
Cdd:MTH00199 100 PILILIVALGSLLLVSSINWLSIYLAIELQTLTlFILVALKRDSAYSTEAGLKYFVLGAVSSGLFLfgcallygltgeTS 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  74 ILSNN-LLSGQWtmtsttnqySSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVvnTN 152
Cdd:MTH00199 180 IQGINsILTGDV---------GKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPV--TN 248

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 153 ILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPN----ITIFNLTIYIVLTTTAF---LALNLNSST 225
Cdd:MTH00199 249 VVLICAVLSIIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSFesiqASLIYMIIYVIMSICSFsiiLSLKLTKGL 328

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 226 TTLL--LSRSWNKLTWLLPLipsTLLSLGGLPPLSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLIystSIT 303
Cdd:MTH00199 329 IVEVsgLSRKNPVIALTLAL---TFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVV---QII 402

                        330
                 ....*....|...
gi 295065582 304 LFPTSNNVkMKWQ 316
Cdd:MTH00199 403 YFQADYSI-LIWQ 414
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-278 6.17e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.22  E-value: 6.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   23 SSHWFLTWVGLEMNMLAFIPILT-KKTNPRSTEAAIKYFLVQATASMILMMAI-----------LSNNLLSGQWTMTSTT 90
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGIslmynytgtlsFDELSKALTGGLNSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   91 NQYSSLMILTALAMKLGMAPFHFWVPEVTQGT-TLTSGLLLLTWQKLAPISIM-----YQIFPVVNTNILLTFSTLSIMV 164
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGApTPVSALLAATLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  165 GSWGGLNQTQLRKILAYSSITHMGWMMAIL----PYNPNITIFNLTIYIVLTTTAFL-ALNLNSSTTTLLLSRSWNKLTW 239
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcAGSVIYRRVHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 295065582  240 LLPLIPSTLLSLGGLPP----LSGFLPKWLVIEELTKNGSLVI 278
Cdd:pfam00361 241 TMPILALVFLVAMLSLAglppTAGFLGKFLILAAAVAASWIFL 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 1.55e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.16  E-value: 1.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  13 VFAGTLIAASSSHWFLTWVGLEMNMLA-FIPILTKKTNPRSTEAAIKYFLVQATASMILMMAI-------------LSNN 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSlFILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCallcgttgglhlsYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  79 LLSGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVntNILLTFS 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNV--NILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 159 TLSIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITI----FNLTIYIVLTTTAFLALNLNSSTTTLLLSRSw 234
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIqaslVYLFIYIIMSICVFSIILALNVYKNLIIEFS- 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295065582 235 nKLTWLLPLIPSTLLSLGGLPP----LSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTRLI 297
Cdd:MTH00196 239 -GLSRRLPILAITLALTFLSIAgippLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 15-221 9.50e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 86.71  E-value: 9.50e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  15 AGTLIAASSSHWFLTWVGLEMNMLAFIpILT--KKTNPRSTEAAIKYFLVQATASMILMMAI-----LSNNLLSGQWTMT 87
Cdd:COG1007  113 LGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGIsllygATGSLNLAGIAAA 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  88 STTNQYSSL-------MILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIFPVVN-------TNI 153
Cdd:COG1007  192 LAAGGANSPllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFpglaadwQLL 271

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 295065582 154 LLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM-AILPYNPNI---TIFNLTIYIVLTTTAFLALNL 221
Cdd:COG1007  272 LAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlGLAAGTPLGvsaALFYLLAYLFMNLGAFAVILL 343
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 7-297 1.59e-18

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 86.16  E-value: 1.59e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582    7 PIIYSAVFAGTLIAASSSHWFLTWVGLEMNMLAF-IPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLLSGQWT 85
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   86 MTSTTNQYSSLM------------ILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIF------- 146
Cdd:TIGR01770 185 FEDLLLFLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  147 PVVNTNILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMMAILPYNPNITIFNLTIYIVLTT-------TAFLAL 219
Cdd:TIGR01770 265 SEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYAlmslgafGVLSLL 344

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  220 NLNSSTTTLLLSrSWNKLTWLLPLIPSTLLSLGGLPP----LSGFLPKWLVIEELTKNGSLVIPTIMAIITLANLYFYTR 295
Cdd:TIGR01770 345 RSYKDEWIEYIS-DFAGLFKTNPILAILILIFMFSLAgippLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 295065582  296 LI 297
Cdd:TIGR01770 424 VV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-224 1.81e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 82.95  E-value: 1.81e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  15 AGTLIAASSSHWFLTWVGLEMNMLA-FIPILTKKTNPRSTEAAIKYFLVQATASMILMMAI-----LSNNL-LSGQWTMT 87
Cdd:PRK05777 114 LGMMVMVSANDLLTLFLGLELLSLPlYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMsllygATGSLsFAGIAKAL 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  88 STTNQYSSL------MILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIF-------PVVNTNIL 154
Cdd:PRK05777 194 ADGSGNSLLllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLLvvafgglSEDWQQVL 273

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295065582 155 LTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM---AILPYNPNITI-FNLTIYIVLTTTAFLALNLNSS 224
Cdd:PRK05777 274 AIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLvglAAGTAEGYSAVlFYLLAYLFMTLGAFGVISLLRR 347
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-192 2.55e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 67.48  E-value: 2.55e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  10 YSAVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLLSGQWTMTST 89
Cdd:COG0651  113 FLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADL 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  90 TNQYSSL----------MILTALAMKLGMAPFHFWVPEVTQGTTltsglllltwqklAPIS-----------------IM 142
Cdd:COG0651  193 AARLAELdpglllaafaLLLVGFGIKAALFPLHFWLPDAYPAAP-------------SPVSallsglltkvgvyailrVL 259

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 295065582 143 YQIFPVVNTN----ILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMMA 192
Cdd:COG0651  260 TLLFGADPALflgtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILL 313
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-191 3.48e-10

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 61.03  E-value: 3.48e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  16 GTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRST---------EAAIKYFLVQATASMILMMAILSNNLLSGQWTM 86
Cdd:MTH00198 200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNEGM 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  87 T--------STTN------QYSSLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAPISIMYQIfpVVNTN 152
Cdd:MTH00198 280 LgtilsatlETTNielrqgSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL--VITSK 357

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 295065582 153 ILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:MTH00198 358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
47-226 7.04e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.98  E-value: 7.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  47 KTNPRSTEAAIKYFLVQATASMI-LMMAILSNNLLSGQWTMTSTTNQY---SSLMILTAL-------AMKLGMAPFHFWV 115
Cdd:PRK02504 154 KRDPRSNEAALKYLLIGAASSAIfLYGSSLLYGLSGGSTQLSAIALALitsPSLGLALALvfviagiAFKISAVPFHQWT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 116 PEVTQGTTLTSGLLLLTWQKLA----PISIMYQIFPVVNTNILLTFSTLSIM---VGSWGGLNQTQLRKILAYSSITHMG 188
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEQWKLLFTALAILsmvLGNVVALAQTSMKRMLAYSSIGQAG 313

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 295065582 189 WMMAILPYNPN----ITIFNLTIYIVLTTTAFLALNLNSSTT 226
Cdd:PRK02504 314 FVMIGLVAGTEagyaSMVFYLLAYLFMNLGAFACVILFSLRT 355
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 12-191 1.65e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 55.72  E-value: 1.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   12 AVFAGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILMMAILSNNLLSG--------- 82
Cdd:TIGR01972 114 LLEAGVIGVFLALDLFLFYVFWEAMLIPMYLLIGVWGGPNRIYAAMKFFLYTLAGSLLMLLAILGLYFLGGgtfdllell 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582   83 QWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEV-TQGTTLTSGLLLLTWQKLAPISIM---YQIFP---VVNTNILL 155
Cdd:TIGR01972 194 NLPLPFGVQTWLFLAFFIAFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLrfnLPLFPdasLYFAPVLA 273

                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 295065582  156 TFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:TIGR01972 274 ALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
ndhB CHL00049
NADH dehydrogenase subunit 2
 47-211 2.19e-08

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 55.40  E-value: 2.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  47 KTNPRSTEAAIKYFLVQATASMILMMAI---------------LSNNLLSGQwtMTSTTNQYSSLMILTA-LAMKLGMAP 110
Cdd:CHL00049 155 KKDVRSNEATMKYLLMGGASSSILVYGFswlyglsggeielqeIVNGLINTQ--MYNSPGISIALIFITVgIGFKLSLAP 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 111 FHFWVPEVTQGTTLTSGLLLLTWQKLA----PISIMYQIFPVVNT---NILLTFSTLSIMVGSWGGLNQTQLRKILAYSS 183
Cdd:CHL00049 233 FHQWTPDVYEGSPTPVVAFLSVTSKVAasalATRIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYSS 312

                        170       180
                 ....*....|....*....|....*....
gi 295065582 184 ITHMGWMM-AILPYNPNITIFNLTIYIVL 211
Cdd:CHL00049 313 IGQIGYVIiGIIVGDSNDGYASMITYMLF 341
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 9.54e-08

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 53.55  E-value: 9.54e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  55 AAIKYFLVQATASMILMMAILSNNLLSGQWTM---TSTTNQYSS-------LMILTALAMKLGMAPFHFWVPEVTQgttl 124
Cdd:COG1008  162 AAIKFFLYTLAGSLLMLVAILALYFLAGALTFdiaELAAAPLPLtaqlllfLAFFIAFAVKVPMFPFHTWLPDAHV---- 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 125 tsglllltwQKLAPISIM-----------------YQIFP---VVNTNILLTFSTLSIMVGSWGGLNQTQLRKILAYSSI 184
Cdd:COG1008  238 ---------EAPTAGSVLlagvllkmggygllrfaLPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSV 308


                 ....*...
gi 295065582 185 THMGWMMA 192
Cdd:COG1008  309 SHMGFVLL 316
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 15-191 1.14e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 53.18  E-value: 1.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  15 AGTLIAASSSHWFLTWVGLEMNMLA-FIPILTKKTNPRSTEAAIKYFLVQATASMILMMAIlsnNLLSGQW---TM---- 86
Cdd:PRK08376 132 LGMLGMAITGDLFNFFVFLEIMSIAsYALVAFRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYgtlNMayla 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  87 ------TSTTNQYSSLMILTALAMKLGMAPFHFWVPE---VTQGTTLTSGLLLLTWQKLAPISIMYQIF-PVVNTN---- 152
Cdd:PRK08376 209 vkmsenPTVVAKIALALFIAGLAMKSGAVPVHMWLPDaypAAPSSISAMLLVIKQAGLYALARVLFSIYgPAINLAtvgw 288

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 295065582 153 ILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK08376 289 VIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYML 327
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-321 5.82e-06

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 43.02  E-value: 5.82e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 295065582  291 YFYTRLIYSTSITLFPTSNNVKMKWQFENTK 321
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTK 31
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 10-191 1.19e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 47.06  E-value: 1.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  10 YSAVFAGTLIAASSSHWFLTWVGLEMNML---AFIPILTKKTNprsTEAAIKYFLVQATASMILMMAILSNNLLSGQWTM 86
Cdd:PRK08676 108 FNLLLSVITFAFFSDNLALFWIFAELTTVfsaMLIAILSAREN---IDAALKYIFIASTAMIFAFIGLIFLFSLTRQALG 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  87 TSTTN----------------QYSSLMILTALAMKLGMAPFHFWVPEV-TQGTTLTSGLLLLTWQKLAPISIMY------ 143
Cdd:PRK08676 185 TGTLNwtelaahasllspsvlGASFLFIFIGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGILRlsallr 264

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 295065582 144 --QIFPVVnTNILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK08676 265 qsGAAEQF-SNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 15-191 2.82e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 45.64  E-value: 2.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  15 AGTLIAASSSHWFLTWVGLEMNMLAFIPILTKKTNPRSTEAAIKYFLVQATASMILM--------------MAILSNNLL 80
Cdd:PRK08375 117 AGLLGALLTADLFNLFVFLEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLigvgllygvtgtlnMADLAGALA 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  81 SGQWTMTSTtnqyssLMILTALAMKLGMAPFHFWVPEVTQGTTLTSGLLLLTWQKLAP----ISIMYQIFPV------VN 150
Cdd:PRK08375 197 ENPTVVTAF------GFVLLALALKAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAvyalIRIYFTVFGGdfrfalGL 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 295065582 151 TNILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK08375 271 GWLLAVLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYIL 311
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 1.96e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 42.88  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  55 AAIKYFLVQATASMILMMAILSnnLLSGQWTMTSTTNqYSSLM---------------ILTALAMKLGMAPFHFWVPEV- 118
Cdd:PRK05846 162 AATKFFLYTLLGSLLMLVAIIY--LVVVYYNATGTFD-IADLLnlplppgvqywlflaFFIAFAVKMPMFPLHTWLPDAh 238

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295065582 119 TQGTTLTSGLLLLTWQKLAP---ISIMYQIFPVVNTN---ILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK05846 239 VQAPTAGSVLLAGILLKMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-191 1.52e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 40.08  E-value: 1.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  55 AAIKYFLVQATASMILMMAILSNNLLSGQWTM------TSTTNQYSSLMILTAL----AMKLGMAPFHFWVPEV-TQGTT 123
Cdd:PRK07363 158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFdydaisTQNLSLNTQLILLTGLllgfGIKIPLVPLHTWLPDAyTEASP 237

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295065582 124 LTSGLLLLTWQKLAPISIM---YQIFPVVNTNI---LLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK07363 238 AVAILLGGVLAKLGTYGLLrfgLQLFPQTWSLVapgLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYIL 311
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 54-211 1.58e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.29  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  54 EAAIKYFLVQATASMILMMAILS----------NNLLSGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEV-TQGT 122
Cdd:MTH00226 182 QAAYYFFFYTLIGSVLMLLCLFSlynihgttdyLTLASCSHVVSEQTQKWIFLGIFLAMAVKIPIFPFHIWLPKAhVEAP 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 123 TLTSGLLLLTWQKLAP---ISIMYQIFPVVNTNI---LLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGwMMAILPY 196
Cdd:MTH00226 262 VAGSVLLAGILLKLGGyglVRLSWPILPLGAQNLapaVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAHMG-LVSITLV 340

                        170
                 ....*....|....*
gi 295065582 197 NPNITIFNLTIYIVL 211
Cdd:MTH00226 341 THDIIGLTGSIFIML 355
PRK12650 PRK12650
DUF4040 family protein;
66-192 5.17e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 38.87  E-value: 5.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  66 ASMILMMAI-----LSNNLLSGQWTMTSTTNQYSSLMILTALAMKLGMAPFHFWVPEVTQGTtltsglllltwqklAPIS 140
Cdd:PRK12650 177 AAVAIAATQtgttsLSGILHSDVWAEKPGLTTVVAVLIAVAAFTKSAQFPFHFWLPEAMAAI--------------TPVS 242

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295065582 141 IMYQIFPVVNTNI--LLTFSTLSIMVGSWGGL-----------------NQTQLRKILAYSSITHMGWMMA 192
Cdd:PRK12650 243 AFLHAAAVVKAGIylLLRFSPVFHDVAVWNWLliivgmitalmgavfavQKTDLKKLTAYSTVSQLGWIVA 313
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 47-193 6.23e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 38.41  E-value: 6.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  47 KTNPRSTEAAIKYFLVQATASMI--------------LMMAILSnnLLSGQWTMTSTTNQYSSLMILTALAM-------- 104
Cdd:PRK12667 157 RDRGDAVEAAIKYALIGAVGTTLyflalaflyatfgtLNMADLS--AKIRGLSFPLTGGLAGNPPLALGVALalalwaft 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582 105 -KLGMAPFHFWVPEVTQGTTltsglllltwqklAPIS-----------------IMYQIF-------PVVNT--NILLTF 157
Cdd:PRK12667 235 iKAAIFPNHFWLPDAHPAAP-------------SPVSamlsglvvnvgayaiirFLYTIFgispsliDFRAAlsPILIIL 301

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 295065582 158 STLSIMVGSWGGLNQTQLRKILAYSSITHMGW-MMAI 193
Cdd:PRK12667 302 GAVSAIIGALMMVVQKDVKRLLAYSTISHMGYiFMGI 338
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 7.23e-03

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 38.09  E-value: 7.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295065582  55 AAIKYFLVQATASMILMMAILSNNLLSGQWT--MTSTTNQYSSLMI--------LTALAMKLGMAPFHFWVP----EVTQ 120
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTFTfdLAELGAKSYPLALelllyagfLIAFGVKLPIFPLHTWLPdahgEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295065582 121 GTTLTSGLLLLTWQKLAPISIMYQIFP---VVNTNILLTFSTLSIMVGSWGGLNQTQLRKILAYSSITHMGWMM 191
Cdd:PRK12561 218 PVSMILAGVLLKMGGYALIRFNVQMLPdahVYFAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVL 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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