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Conserved domains on  [gi|589144303|ref|YP_009003601|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Praslinia cooperi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 23-330 5.18e-141

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 403.03  E-value: 5.18e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELS-TLPSNMMTIAL 101
Cdd:MTH00135  23 SSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMShPLPTTMITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 102 LMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSlNPTLLMTLGLTSILLGGWLGLNQTQLRKIMASS 181
Cdd:MTH00135 103 ALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLTSTLVGGWGGLNQTQLRKILAYS 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 182 SIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMP 261
Cdd:MTH00135 182 SIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMP 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 589144303 262 KWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPNQSTTALTLMTI 330
Cdd:MTH00135 262 KWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAISTT 330
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 23-330 5.18e-141

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 403.03  E-value: 5.18e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELS-TLPSNMMTIAL 101
Cdd:MTH00135  23 SSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMShPLPTTMITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 102 LMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSlNPTLLMTLGLTSILLGGWLGLNQTQLRKIMASS 181
Cdd:MTH00135 103 ALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLTSTLVGGWGGLNQTQLRKILAYS 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 182 SIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMP 261
Cdd:MTH00135 182 SIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMP 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 589144303 262 KWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPNQSTTALTLMTI 330
Cdd:MTH00135 262 KWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAISTT 330
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-285 9.04e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.53  E-value: 9.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   23 SSHWLLAWTGLEINTLAIIPLMIKNH-HPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSNM----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGkSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   97 -------MTIALLMKLGVAPMHFWLPEVLQGVDLTTGLIL-STWQKLAP-----MSLMFMIHNSLNPTLLMTLGLTSILL 163
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  164 GGWLGLNQTQLRKIMASSSIAHLGWMMIIlpLSPPLFILNIIIYIIMTSALFLSMMFF--------NMTKFNSLTTS--- 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIA--LGAGTIYGIQAAIFHLLTHGLFSAGLFlcagsviyRRVHTRNIRDYggl 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 589144303  233 WSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISA 285
Cdd:pfam00361 239 AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-294 2.46e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 88.63  E-value: 2.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPL-MIKNHHPRATEATTKYFLTQATASTLILF-STMTNAwLTGEWELKELSTLPSN----- 95
Cdd:COG1007  121 ANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAAALAAggans 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  96 --------MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNP-------TLLMTLGLTS 160
Cdd:COG1007  200 pllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPglaadwqLLLAVLAVLS 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 161 ILLGGWLGLNQTQLRKIMASSSIAHLGWMMIIL----PLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTS---- 232
Cdd:COG1007  280 MTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAFAVILLLSRKGGEAEEIEdlag 359

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 589144303 233 -WSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLR 294
Cdd:COG1007  360 lARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-294 1.21e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 80.38  E-value: 1.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   23 SSHWLLAWTGLEINTLAIIPLM-IKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN------ 95
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNgmlnis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   96 -------MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAP----MSLMFMIHNSLNPT---LLMTLGLTSI 161
Cdd:TIGR01770 201 llllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavfLRLFLYILFGFSEAwqiFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  162 LLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPL-------SPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTT--S 232
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtlegikAVLFYIFIYALMSLGAFGVLSLLRSYKDEWIEYISDfaG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 589144303  233 WSKT-PTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLR 294
Cdd:TIGR01770 361 LFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 23-330 5.18e-141

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 403.03  E-value: 5.18e-141
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELS-TLPSNMMTIAL 101
Cdd:MTH00135  23 SSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWDIQQMShPLPTTMITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 102 LMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSlNPTLLMTLGLTSILLGGWLGLNQTQLRKIMASS 181
Cdd:MTH00135 103 ALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLTSTLVGGWGGLNQTQLRKILAYS 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 182 SIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMP 261
Cdd:MTH00135 182 SIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMP 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 589144303 262 KWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPNQSTTALTLMTI 330
Cdd:MTH00135 262 KWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQLTLPLAISTT 330
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-330 6.30e-131

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 377.34  E-value: 6.30e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   1 MSPLTLIIVLVSLLLGTTLTITSSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  81 TGEWELKELST-LPSNMMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMTLGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTpLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 160 SILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 240 AISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKpN 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-N 319

                        330
                 ....*....|.
gi 589144303 320 QSTTALTLMTI 330
Cdd:MTH00070 320 KTNNLLSLTII 330
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-330 8.07e-116

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 339.11  E-value: 8.07e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   1 MSPLTLIIVLVSLLLGTTLTITSSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  81 TGEWELKELSTLPSN-MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMTLGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCtLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 160 SILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 240 AISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPN 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330
                 ....*....|.
gi 589144303 320 QSTTALTLMTI 330
Cdd:MTH00112 321 KNTLTATLTTL 331
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-330 6.10e-110

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 324.11  E-value: 6.10e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   1 MSPLTLIIVLVSLLLGTTLTITSSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  81 TGEWEL-KELSTLPSNMMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMTLGLT 159
Cdd:MTH00105  81 SGQWTItKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 160 SILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 240 AISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPN 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|.
gi 589144303 320 QSTTALTLMTI 330
Cdd:MTH00105 321 KPMTLLPTLII 331
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-319 5.68e-86

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 262.98  E-value: 5.68e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   1 MSPLTLIIVLVSLLLGTTLTITSSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  81 TGEWELKE-LSTLPSNMMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMTLGLT 159
Cdd:MTH00200  81 SGQWGISEmLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 160 SILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 240 AISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPN 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 23-327 8.25e-79

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 244.84  E-value: 8.25e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKE-LSTLPSNMMTIAL 101
Cdd:MTH00041  23 SNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSGSWSINGpLNTLSSIIITLAL 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 102 LMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMTLGLTSILLGGWLGLNQTQLRKIMASS 181
Cdd:MTH00041 103 ALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGILSVLVGGWGGLNQTQTRKILAFS 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 182 SIAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMP 261
Cdd:MTH00041 183 SIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFLN 262

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 589144303 262 KWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTINSQVTWRLKPNQSTTALTL 327
Cdd:MTH00041 263 KFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVYGVIL 328
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 23-307 8.17e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 166.92  E-value: 8.17e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLtgeweLKELSTLPSNMMTIALL 102
Cdd:MTH00160  24 SNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN-----LMLFNNISSMLINSSLL 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 103 MKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSlnpTLLMTLGLTSILLGGWLGLNQTQLRKIMASSS 182
Cdd:MTH00160  99 LKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINN---NFIIIIIILSAIIGAIGGLNQTSLRKILAYSS 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 183 IAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMPK 262
Cdd:MTH00160 176 INHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFLGFLPK 255

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 589144303 263 WLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPST 307
Cdd:MTH00160 256 WIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 23-301 4.41e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 154.27  E-value: 4.41e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELkelstlpSNMMTIALL 102
Cdd:MTH00144  23 SSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS-------MSLLLLGLC 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 103 MKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNP-TLLMTLGLTSILLGGWLGLNQTQLRKIMASS 181
Cdd:MTH00144  96 LKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIGGLNQTQVRALLAYS 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 182 SIAHLGWMMIILPLSPPLFILNIIIYIiMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMP 261
Cdd:MTH00144 176 SISHTGWMLVAILHGSWLMWMYFLIYI-VSSGFLFFSLWSGDSGSMKDLGSLKPSYKTGLSIISLLLSLGGLPPFLGFCS 254

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 589144303 262 KWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLAL 301
Cdd:MTH00144 255 KLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 23-298 2.09e-39

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 141.84  E-value: 2.09e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFStMTNAWLTgeweLKELSTLPSNMMTIALL 102
Cdd:MTH00011  25 SNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLG-MTMMWSF----PSLLKNITALMLLVSLM 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 103 MKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMTLGLTSILLGGWLGLNQTQLRKIMASSS 182
Cdd:MTH00011 100 LKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGMNQTQLRPLLAYSS 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 183 IAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMPK 262
Cdd:MTH00011 180 IGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFTGFMPK 259

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 589144303 263 WLILQELTKQHFLTMATLMAISALLSLFFYLRMSYS 298
Cdd:MTH00011 260 LMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 23-298 3.63e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 130.56  E-value: 3.63e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMtnawltGEWELKELSTLPSNMMTIALL 102
Cdd:MTH00197  17 SSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS------LSFSNLYLSLLSVVLVILGLL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 103 MKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPmsLMFMIHNSLNPTLLMTLGLTSILLGGWLGLNQTQLRKIMASSS 182
Cdd:MTH00197  91 LKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAP--LLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSNIRQLLAYSS 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 183 IAHLGWMMIILPLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMPK 262
Cdd:MTH00197 169 IGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLSGFFLK 248

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 589144303 263 WLILQELTKQHFLTMATLMAISALLSLFFYLRMSYS 298
Cdd:MTH00197 249 WLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYK 284
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-285 9.04e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.53  E-value: 9.04e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   23 SSHWLLAWTGLEINTLAIIPLMIKNH-HPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSNM----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGkSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   97 -------MTIALLMKLGVAPMHFWLPEVLQGVDLTTGLIL-STWQKLAP-----MSLMFMIHNSLNPTLLMTLGLTSILL 163
Cdd:pfam00361  81 llllfllILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGyglirRSLLYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  164 GGWLGLNQTQLRKIMASSSIAHLGWMMIIlpLSPPLFILNIIIYIIMTSALFLSMMFF--------NMTKFNSLTTS--- 232
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIA--LGAGTIYGIQAAIFHLLTHGLFSAGLFlcagsviyRRVHTRNIRDYggl 238

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 589144303  233 WSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISA 285
Cdd:pfam00361 239 AKTMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 23-295 1.08e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 88.93  E-value: 1.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHP-RATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN------ 95
Cdd:MTH00196  12 SSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSYINLVLNSgqsfss 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  96 --------MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNptLLMTLGLTSILLGGWL 167
Cdd:MTH00196  92 vsvpigylLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGGLFSLFVGAIG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 168 GLNQTQLRKIMASSSIAHLGWMMIILPL----SPPLFILNIIIYIIMTSALFLSMMFFNMTKfnSLTTSWS----KTPTL 239
Cdd:MTH00196 170 ALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSICVFSIILALNVYK--NLIIEFSglsrRLPIL 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 589144303 240 AISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRM 295
Cdd:MTH00196 248 AITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 23-294 2.46e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 88.63  E-value: 2.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPL-MIKNHHPRATEATTKYFLTQATASTLILF-STMTNAwLTGEWELKELSTLPSN----- 95
Cdd:COG1007  121 ANDLLTLFLGLELLSLSLYVLvAFRRDDRRSSEAALKYFLLGALSSGFLLYgISLLYG-ATGSLNLAGIAAALAAggans 199

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  96 --------MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNP-------TLLMTLGLTS 160
Cdd:COG1007  200 pllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPglaadwqLLLAVLAVLS 279

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 161 ILLGGWLGLNQTQLRKIMASSSIAHLGWMMIIL----PLSPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTTS---- 232
Cdd:COG1007  280 MTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYLFMNLGAFAVILLLSRKGGEAEEIEdlag 359

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 589144303 233 -WSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLR 294
Cdd:COG1007  360 lARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLR 422
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 23-295 4.55e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 84.68  E-value: 4.55e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAI-IPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN-----M 96
Cdd:MTH00199 116 SINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINSILTGdvgkiL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  97 MTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPTLLMtlGLTSILLGGWLGLNQTQLRK 176
Cdd:MTH00199 196 ITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLIC--AVLSIIYGAIGALNQTKIKR 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 177 IMASSSIAHLGwmMIILPLSPPLFILNIIIY------IIMTSALFLSMMFFNMTKfnSLTTSWS----KTPTLAISSSIL 246
Cdd:MTH00199 274 LLAYSGIGHMG--FILFGVAIGSFESIQASLiymiiyVIMSICSFSIILSLKLTK--GLIVEVSglsrKNPVIALTLALT 349

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 589144303 247 LLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRM 295
Cdd:MTH00199 350 FLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-295 2.98e-17

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 82.12  E-value: 2.98e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  30 WTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN-----------MMT 98
Cdd:COG0651  133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAEldpglllaafaLLL 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  99 IALLMKLGVAPMHFWLPE-----------VLQGVDLTTGL--ILSTWQKLAPMSLMFMIHnslnpTLLMTLGLTSILLGG 165
Cdd:COG0651  213 VGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLG-----TLLLVLGLLTMLVGA 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 166 WLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLFILN----IIIYIIMTSALFLS----MMFFNMTKFNSLTTSWSKTP 237
Cdd:COG0651  288 LGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGalfhLLNHALAKALLFLAagaiERATGTRDLDKLGGLGKRMP 367

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 589144303 238 TLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRM 295
Cdd:COG0651  368 LTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
23-294 4.09e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 81.79  E-value: 4.09e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPL-MIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN------ 95
Cdd:PRK05777 122 ANDLLTLFLGLELLSLPLYALaALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKALADgsgnsl 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  96 -------MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMF----MIHNSLNPT---LLMTLGLTSI 161
Cdd:PRK05777 202 lllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLrllvVAFGGLSEDwqqVLAIIAIASM 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 162 LLGGWLGLNQTQLRKIMASSSIAHLGWMMI------ILPLSPPLFILNIIIYIIMTSALFLSMMF---FNMTKFNSLTTS 232
Cdd:PRK05777 282 LVGNLAALSQTNIKRLLAYSSIAHAGYLLVglaagtAEGYSAVLFYLLAYLFMTLGAFGVISLLRrkgGEAESISDFAGL 361

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 589144303 233 WSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLR 294
Cdd:PRK05777 362 SKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLR 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-294 1.21e-16

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 80.38  E-value: 1.21e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   23 SSHWLLAWTGLEINTLAIIPLM-IKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN------ 95
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAgLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNgmlnis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303   96 -------MMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTWQKLAP----MSLMFMIHNSLNPT---LLMTLGLTSI 161
Cdd:TIGR01770 201 llllgivLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIfavfLRLFLYILFGFSEAwqiFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  162 LLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPL-------SPPLFILNIIIYIIMTSALFLSMMFFNMTKFNSLTT--S 232
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAgtlegikAVLFYIFIYALMSLGAFGVLSLLRSYKDEWIEYISDfaG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 589144303  233 WSKT-PTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLR 294
Cdd:TIGR01770 361 LFKTnPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 23-191 5.59e-10

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 60.64  E-value: 5.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  23 SSHWLLAWTGLEINTLAIIPLMIKNHHPRAT---------EATTKYFLTQATASTLILFSTMTNAWLTGE---------- 83
Cdd:MTH00198 207 SANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegmlgtilsa 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  84 ------WELKELStLPSNMMTIALLMKLGVAPMHFWLPEVLQGVDLTTGLILSTwqklAPMSLMFMIHNSLNPT--LLMT 155
Cdd:MTH00198 287 tlettnIELRQGS-LGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAI----IPKFTVYILLTSLVITskLLLS 361

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 589144303 156 LGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMI 191
Cdd:MTH00198 362 VAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILI 397
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 34-309 5.83e-09

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 57.31  E-value: 5.83e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  34 EINTLAIIpLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELSTLPSN------------MMTIAL 101
Cdd:PRK08668 128 EIMTFSSF-MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADISQGLINdtstgfalivflFLLAFG 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 102 LMKLGVAPMHFWLPE-----------VLQGVDLTTG---LILSTW----QKLAPMSLMFMIHNSLNpTLLMTLGLTSILL 163
Cdd:PRK08668 207 VAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLGaygFLLVLYvlpgTKLFSEFGTYRGVPLFN-YILAWLGNISIIV 285

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 164 GGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLfILNIIIYIIMTSALFLSMMFFNM---------TKFNSLTTSWS 234
Cdd:PRK08668 286 GTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSL-GFAGGLFHVFNHALFKGLFFLIFaaviyrtgtTKISEMGGLIE 364

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 589144303 235 KTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPSTIN 309
Cdd:PRK08668 365 KMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLAGVFLGQLPSDHK 439
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-299 5.95e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 54.11  E-value: 5.95e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  33 LEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFSTMTNAWLTGEWELKELST-LPSN--------MMTIALLM 103
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGaLAENptvvtafgFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 104 KLGVAPMHFWLPEVLQGVDLTTGLILS-TWQKLAPMSLM----------FMIHNSLNpTLLMTLGLTSILLGGWLGLNQT 172
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLG-WLLAVLALLSMLVGSLAALGQD 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 173 QLRKIMASSSIAHLGWMMIILPLSPPLFILNIIIYII----MTSALFLS----MMFFNMTKFNSLTTSWSKTPTLAISSS 244
Cdd:PRK08375 294 DVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLhhalMKGALFLAagaiEVTYGTRRLSELSGLGRRMPLTAAAFA 373

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 589144303 245 ILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSL 299
Cdd:PRK08375 374 VASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRA 428
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 96-345 2.11e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 52.28  E-value: 2.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  96 MMTIALLMKLGVAPMHFWLPEV-----------LQGVDLTTG---------LILSTWQKLAPMSLMFMIhnslnptLLMT 155
Cdd:PRK12667 228 LALWAFTIKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAALSP-------ILII 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 156 LGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPL----FILNIIIYIIMTSALFLSMMFF----NMTKFN 227
Cdd:PRK12667 301 LGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLglaaALFHIINHAIAKSLLFLASGVFihaaGTRDID 380

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 228 SLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPST 307
Cdd:PRK12667 381 ELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYSLFFGKPKSG 460

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 589144303 308 INSQVTWRLKPNQSTTALTLMTILSLTLLPLTPYFIMT 345
Cdd:PRK12667 461 EEVEHKESPSMSVVILVLALAVLILGILALFLPEILDS 498
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 49-191 9.76e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 50.08  E-value: 9.76e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  49 HPRATEATTKYFLTQATASTLILFSTMTNAWLTGEW-----ELKELStLPSNM-------MTIALLMKLGVAPMHFWLPE 116
Cdd:COG1008  156 GERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfdiaELAAAP-LPLTAqlllflaFFIAFAVKVPMFPFHTWLPD 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 117 -----------VLQGVDLTTG----------LILSTWQKLAPmslmfmihnslnptLLMTLGLTSILLGGWLGLNQTQLR 175
Cdd:COG1008  235 ahveaptagsvLLAGVLLKMGgygllrfalpLFPEASAYFAP--------------LLAALGVIGIIYGALVALAQTDLK 300

                        170
                 ....*....|....*.
gi 589144303 176 KIMASSSIAHLGWMMI 191
Cdd:COG1008  301 RLIAYSSVSHMGFVLL 316
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 151-330 2.72e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 48.96  E-value: 2.72e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 151 TLLMTLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWmmIILPLSPPLFILNIIIYIIMT------SALFLSM----MF 220
Cdd:PRK12662 280 NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGY--IILAVSLNTYYGLAAAVAYIVnhsivkSALFMVSgsisYH 357

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 221 FNMTKFNSLTTSWSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLA 300
Cdd:PRK12662 358 FGTTKLEDCLNLWKSMPKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNAWIGLVVLLVGSGLSVIYVWKIVEALY 437

                        170       180       190
                 ....*....|....*....|....*....|
gi 589144303 301 LTQSPSTINSQVTWRLKPNQSTTALTLMTI 330
Cdd:PRK12662 438 FESRMVESKANDKAFKTPNAMVLCIWIMAI 467
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 28-308 3.89e-06

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 48.39  E-value: 3.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  28 LAWTGLEINTLAIIPLMIKNHHPRATEATTKYFLTQATASTLILFST----MTNAWLTGEWELKELST--------LPSN 95
Cdd:PRK06458 132 LMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTilvyANAATVMGDGEMAILWTellkhaslLDPT 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  96 MMTIA---LLM----KLGVAPMHFWLPE-----------VLQGVDLTTGL-ILSTWQKLAPMSlmfmIHNSLNPTLLMTL 156
Cdd:PRK06458 212 LMKLAfvfLLIgfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALyAVLRYYILIDAA----IGSDFPGRLLLIF 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 157 GLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSPPLFILNIIIYIIMTSaLFLSMMFF------------NMT 224
Cdd:PRK06458 288 GLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALGIGGPLGIFAALLHMLNHS-LTKSAIFFasgnvlqkygtrDIN 366

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 225 KFNSLTTSwskTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQS 304
Cdd:PRK06458 367 VIRGLLKV---SPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLARGPLLIAILLLLLLTLAFAALVRRVAGMVFGEP 443


                 ....
gi 589144303 305 PSTI 308
Cdd:PRK06458 444 PEAV 447
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 7.38e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 47.40  E-value: 7.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  33 LEINTLAIIPLM-IKNHHPRATEATTKYFLTQATASTLILFSTmtnAWLTGEWELKELSTLPSNM--------------M 97
Cdd:PRK08376 150 LEIMSIASYALVaFRNDTWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMsenptvvakialalF 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  98 TIALLMKLGVAPMHFWLPEVLQGV--DLTTGLILSTWQKL-APMSLMFMIHN-SLNPT----LLMTLGLTSILLGGWLGL 169
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPDAYPAApsSISAMLLVIKQAGLyALARVLFSIYGpAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180
                 ....*....|....*....|..
gi 589144303 170 NQTQLRKIMASSSIAHLGWMMI 191
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYMLL 328
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 78-295 1.53e-05

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 46.68  E-value: 1.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  78 AWLTGEWELKEL-----STLPSNMMTIALLMKLGVA-------PMHFWLPEVLQG-----------VDLTTGLILstwqk 134
Cdd:COG1009  186 GAIAGTLNFSELlaaapTILSSPLLTLILLLLLLGAfgksaqfPLHFWLPDAMEGptpvsallhaaTMVKAGVYL----- 260

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 135 LAPMSLMFmihnSLNPT---LLMTLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSpplfILNIIIYIIMT 211
Cdd:COG1009  261 LARLSPLF----ALSPVwltVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLALGVG----AYVAALFHLLT 332

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 212 SALFLSMMFF------------NMTKFNSLttsWSKTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMA- 278
Cdd:COG1009  333 HAFFKALLFLgagsvihatgtrDIRKMGGL---RKKMPITAITFLIGALSLAGIPPFAGFFSKEAILEAALEAGGLGPLl 409

                        250
                 ....*....|....*...
gi 589144303 279 -TLMAISALLSLFFYLRM 295
Cdd:COG1009  410 lAVALLGAFLTAFYSFRL 427
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-321 6.62e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 44.61  E-value: 6.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  51 RATEATTKYFLTQATASTLILFSTmtnAWLTG----EWELKE-----LSTLPSN---------MMTIALLMKLGVAPMHF 112
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGF---SWLYGlsggEIELQEivnglINTQMYNspgisialiFITVGIGFKLSLAPFHQ 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 113 WLPEVLQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNPT-------LLMTLGLTSILLGGWLGLNQTQLRKIMASSSIAH 185
Cdd:CHL00049 236 WTPDVYEGSPTPVVAFLSVTSKVAASALATRIFDIPFYFssnewhlLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQ 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 186 LGWMMI-ILPLSPPlfILNIIIYIIMTSALFLSMMFFNMTKFNSLTT----------SWSKTPTLAISSSILLLSLGGLP 254
Cdd:CHL00049 316 IGYVIIgIIVGDSN--DGYASMITYMLFYIFMNLGTFACIVLFGLRTgtdnirdyagLYTKDPFLALSLALCLLSLGGIP 393

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 255 PTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLRMSYSLALTQSPST---INSQVTWRLKPNQS 321
Cdd:CHL00049 394 PLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIIKLLMTGRNQEItpyVRNYRRSPLRSNNS 463
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 1.77e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 43.10  E-value: 1.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  55 ATTKYFLTQATASTLILFSTMTNAWLTGE--WELKELsTLPSNMMTIALL----------MKLGVAPMHFWLPE------ 116
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAEL-GAKSYPLALELLlyagfliafgVKLPIFPLHTWLPDahgeas 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 117 -----VLQGVDLTTG---LILSTWQKLAPMSLMFmihnslnPTLLMTLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGW 188
Cdd:PRK12561 217 apvsmILAGVLLKMGgyaLIRFNVQMLPDAHVYF-------APALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGF 289


                 ...
gi 589144303 189 MMI 191
Cdd:PRK12561 290 VLL 292
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
50-199 4.25e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 41.99  E-value: 4.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  50 PRATEATTKYFLTQATASTLILFSTMTNAWLTG----EWELKELSTLPSN---MMTIALLMKLGVA----PMHFWLPE-- 116
Cdd:PRK06473 153 QRRGYAATKFLLYTAISGILILVSFLGLVWLSGassfDYEPLRSHTLPLStqlLLLAPILVGFGIKiplvPFHTWLPDah 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 117 ---------VLQGVDLTTG----------LILSTWQKLAPMslmfmihnslnptlLMTLGLTSILLGGWLGLNQTQLRKI 177
Cdd:PRK06473 233 veastpvsvLLAGVLLKLGtygllrfgvgLFPEAWVYLAPW--------------LATWAVVSVLYGASCAIAQKDMKKM 298

                        170       180
                 ....*....|....*....|..
gi 589144303 178 MASSSIAHLGWMMIILPLSPPL 199
Cdd:PRK06473 299 VAYSSIGHMGYILLAAAAATPL 320
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 89-297 5.32e-04

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 41.60  E-value: 5.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  89 LSTLPSNMMT-IALLMKLGVAP------MHFWLPEVLQGVDLTTGLILSTWQKLAPMSLMfmIHNS----LNPTLLM--- 154
Cdd:MTH00020 201 VVSAPSSDITlICLFLFIGAVGksaqlgLHTWLPDAMEGPTPVSALIHAATMVTAGVFLL--IRSSplfeQAPLALIivt 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 155 TLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMIILPLSpplfILNIIIYIIMTSALFLSMMFF------------- 221
Cdd:MTH00020 279 IVGSLTVFFAATVGLVQNDLKKVIAYSTCSQLGYMVVACGLS----HYSISLFHLMNHAFFKALLFLsagsvihalsdeq 354

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 589144303 222 NMTKFNSLTTSwskTPTLAISSSILLLSLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAI-SALLSLFFYLRMSY 297
Cdd:MTH00020 355 DMRKMGGLISF---LPLTYIFFLIGSLSLMGFPYLTGFYSKDLILELAFGQYYLIFAYWLGCfSALLTAFYSIRLIY 428
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-330 9.34e-04

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 36.85  E-value: 9.34e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 589144303  290 FFYLRMSYSLALTQSPSTINSQVTWRLKPNQSTTALTLMTI 330
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTT 41
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
50-294 1.78e-03

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 40.03  E-value: 1.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  50 PRATEATTKYFLTQATASTLILF-STMTNAWLTGEWELKE----LSTLPSNMMTIALLM-------KLGVAPMHFWLPEV 117
Cdd:PRK02504 157 PRSNEAALKYLLIGAASSAIFLYgSSLLYGLSGGSTQLSAialaLITSPSLGLALALVFviagiafKISAVPFHQWTPDV 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 118 LQGVDLTTGLILSTWQKLAPMSLMFMIHNSLNP-------TLLMTLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMM 190
Cdd:PRK02504 237 YEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFPsfdeqwkLLFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVM 316

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303 191 IILplspplfilniiiyIIMTSALFLSMMFF-------NMTKFN-----SLTTS----------WSKTPTLAISSSILLL 248
Cdd:PRK02504 317 IGL--------------VAGTEAGYASMVFYllaylfmNLGAFAcvilfSLRTGtdqisdyaglYQKDPLLTLGLSLCLL 382

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 589144303 249 SLGGLPPTTGFMPKWLILQELTKQHFLTMATLMAISALLSLFFYLR 294
Cdd:PRK02504 383 SLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 151-191 2.96e-03

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 39.42  E-value: 2.96e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 589144303 151 TLLMTLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMI 191
Cdd:PRK05846 278 PIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTL 318
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-193 7.16e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 38.37  E-value: 7.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 589144303  81 TGEWELKEL--STLPSNMMTIAL-------LMKLGVAPMHFWLPE-----------------VLQGVDLttglilstwqk 134
Cdd:PRK12644 184 AGTYRLSELlaDPPTGPAVSVAVvlilvgaLSKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYL----------- 252

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 589144303 135 LAPMSLMFMIHNSLNPTLLmTLGLTSILLGGWLGLNQTQLRKIMASSSIAHLGWMMIIL 193
Cdd:PRK12644 253 VARLAPGFADVPVWRPTVL-VLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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