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Conserved domains on  [gi|1418580809|ref|YP_009489720|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Leontopithecus chrysopygus]

Protein Classification

NADH-ubiquinone oxidoreductase chain 4L( domain architecture ID 10009568)

NADH-ubiquinone oxidoreductase chain 4L is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) and is believed to belong to the minimal assembly required for catalysis; Complex I functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.32e-37

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177169  Cd Length: 98  Bit Score: 120.81  E-value: 2.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  1 MPFIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLIL 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1418580809 81 VSNLYGLDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.32e-37

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 120.81  E-value: 2.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  1 MPFIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLIL 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1418580809 81 VSNLYGLDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-98 1.11e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.95  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  4 IYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLILVSN 83
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYR 80

                         90
                 ....*....|....*
gi 1418580809 84 LYGLDYVQNLNLLQC 98
Cdd:pfam00420 81 THGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.32e-37

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 120.81  E-value: 2.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  1 MPFIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLIL 80
Cdd:MTH00107   1 MSLIYMNIMLAFTISLLGLLMYRSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMPIILLVFAACEAAVGLALLVM 80

                         90
                 ....*....|....*...
gi 1418580809 81 VSNLYGLDYVQNLNLLQC 98
Cdd:MTH00107  81 VSNTYGTDYVQNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 11-98 5.40e-23

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 84.63  E-value: 5.40e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809 11 AYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLILVSNLYGLDYV 90
Cdd:MTH00126  11 AFILGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAAPMLLLAFSACEASAGLALLVATARTHGTDRL 90


                 ....*...
gi 1418580809 91 QNLNLLQC 98
Cdd:MTH00126  91 QNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 1-98 1.25e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 81.05  E-value: 1.25e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  1 MPFIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLIL 80
Cdd:MTH00125   1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMPIILLTFSACEAGTGLALLVA 80

                         90
                 ....*....|....*...
gi 1418580809 81 VSNLYGLDYVQNLNLLQC 98
Cdd:MTH00125  81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 8.12e-19

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 73.87  E-value: 8.12e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  1 MPFIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLIL 80
Cdd:MTH00067   1 MSPTYFTFYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSLPMFMLTFSACEASTGLALMVA 80

                         90
                 ....*....|....*...
gi 1418580809 81 VSNLYGLDYVQNLNLLQC 98
Cdd:MTH00067  81 TTRTHGTDHLKNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 9-96 5.50e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 58.80  E-value: 5.50e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  9 MLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLILVSNLYGLD 88
Cdd:MTH00181   6 ISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRTHGSD 85


                 ....*...
gi 1418580809 89 YVQNLNLL 96
Cdd:MTH00181  86 HLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
4-98 1.11e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.95  E-value: 1.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  4 IYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLILVSN 83
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLLRRNLLRVLLSLELMLNAVNLALVLFGRLTADPLPQALILTAIVIAAAEAAVGLALLVRIYR 80

                         90
                 ....*....|....*
gi 1418580809 84 LYGLDYVQNLNLLQC 98
Cdd:pfam00420 81 THGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 1-97 3.36e-09

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 49.53  E-value: 3.36e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  1 MPFIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMPLILLVFAACEAAVGLALLIL 80
Cdd:MTH00043   1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNLSFSLLLLTLSACEASIGLSLMVL 80

                         90
                 ....*....|....*..
gi 1418580809 81 VSNLYGLDYVQNLNLLQ 97
Cdd:MTH00043  81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 9-98 1.27e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 47.92  E-value: 1.27e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  9 MLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTtfNMHFMLMYMMPLILLVFAACEAAVGLALLILVSNLYGLD 88
Cdd:MTH00149  10 LFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSS--SGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGND 87

                         90
                 ....*....|
gi 1418580809 89 YVQNLNLLQC 98
Cdd:MTH00149  88 YVSSLSSLKF 97
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 13-98 2.50e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 44.58  E-value: 2.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809 13 FMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMhfMLMYMMPLILLVFAACEAAVGLALLILVSNLYGLDYVQN 92
Cdd:MTH00188  14 VLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYM--EKELYLSLVLLTFAACEASVGLALLVSLIRSHGSDYVSS 91


                 ....*.
gi 1418580809 93 LNLLQC 98
Cdd:MTH00188  92 LNLIKC 97
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-92 3.20e-07

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 43.99  E-value: 3.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  3 FIYINVMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHFMLMYMMplILLVFAACEAAVGLALLILVS 82
Cdd:MTH00162   2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLL--FFLTFSVCEGALGLSILVSMI 79

                         90
                 ....*....|
gi 1418580809 83 NLYGLDYVQN 92
Cdd:MTH00162  80 RSHGNDYFSS 89
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 8-98 4.03e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 38.96  E-value: 4.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1418580809  8 VMLAYFMSLLGLLIYRSHLMSSLLCLEGMMLSLFIMITLTTFNMHfMLMYMMPLILLVFAACEAAVGLALLILVSNLYGL 87
Cdd:MTH00013   8 LSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFAN-QVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGN 86

                         90
                 ....*....|.
gi 1418580809 88 DYVQNLNLLQC 98
Cdd:MTH00013  87 DMLKSLTSNKC 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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