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Conserved domains on  [gi|1778128448|ref|YP_009711051|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Vespula flaviceps]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-320 8.60e-39

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 139.57  E-value: 8.60e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMYSKNFK--STFNFFIIQSISSLMLIM--LMMIKNDFYFNTTFNLLLILVFSL 76
Cdd:MTH00160   20 ISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSseSSLKYFLIQALASIILLFsiILNMLNLMLFNNISSMLINSSLLL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  77 KLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNqinnptlMYTIISLTISSSLITTIMNYNETNFKKILT 156
Cdd:MTH00160  100 KLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-------NNFIIIIIILSAIIGAIGGLNQTSLRKILA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 157 YSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNyNKINFIISLNFLIISALPPFLT 236
Cdd:MTH00160  173 YSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKS-KKIKFLLFLNLLSLGGLPPFLG 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 237 FMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNMMSMMKTKFFHSYNFNIKFNFFSSIFLSFLSLFFMFFL 316
Cdd:MTH00160  252 FLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFLSFISLFGLILSSL 331


                  ....
gi 1778128448 317 FNSI 320
Cdd:MTH00160  332 LFLL 335
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-320 8.60e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 139.57  E-value: 8.60e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMYSKNFK--STFNFFIIQSISSLMLIM--LMMIKNDFYFNTTFNLLLILVFSL 76
Cdd:MTH00160   20 ISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSseSSLKYFLIQALASIILLFsiILNMLNLMLFNNISSMLINSSLLL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  77 KLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNqinnptlMYTIISLTISSSLITTIMNYNETNFKKILT 156
Cdd:MTH00160  100 KLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-------NNFIIIIIILSAIIGAIGGLNQTSLRKILA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 157 YSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNyNKINFIISLNFLIISALPPFLT 236
Cdd:MTH00160  173 YSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKS-KKIKFLLFLNLLSLGGLPPFLG 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 237 FMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNMMSMMKTKFFHSYNFNIKFNFFSSIFLSFLSLFFMFFL 316
Cdd:MTH00160  252 FLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFLSFISLFGLILSSL 331


                  ....
gi 1778128448 317 FNSI 320
Cdd:MTH00160  332 LFLL 335
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 68-241 3.23e-07

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 50.77  E-value: 3.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  68 LLLILVFSLKLGLFPFFFWPPLINMNLNWML-IFIMSTSQKL-IPLLILNSFFNQINNPTLMYTIISLTISSSLITTIMN 145
Cdd:pfam00361  86 LLILVGFLFKSAQVPFHTWLPDAYEGAPTPVsALLAATLVKAgGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAA 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 146 YNETNFKKILTYSSTNHLSWMIFILM------FDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDL-MKFQFFNYNKIN 218
Cdd:pfam00361 166 LVQTDIKRLLAYSSISHMGYMLIALGagtiygIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIrDYGGLAKTMPIL 245

                         170       180
                  ....*....|....*....|....
gi 1778128448 219 FI-ISLNFLIISALPPFLTFMIKI 241
Cdd:pfam00361 246 ALvFLVAMLSLAGLPPTAGFLGKF 269
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-320 8.60e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 139.57  E-value: 8.60e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMYSKNFK--STFNFFIIQSISSLMLIM--LMMIKNDFYFNTTFNLLLILVFSL 76
Cdd:MTH00160   20 ISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSseSSLKYFLIQALASIILLFsiILNMLNLMLFNNISSMLINSSLLL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  77 KLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNqinnptlMYTIISLTISSSLITTIMNYNETNFKKILT 156
Cdd:MTH00160  100 KLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLIN-------NNFIIIIIILSAIIGAIGGLNQTSLRKILA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 157 YSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNyNKINFIISLNFLIISALPPFLT 236
Cdd:MTH00160  173 YSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKS-KKIKFLLFLNLLSLGGLPPFLG 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 237 FMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNMMSMMKTKFFHSYNFNIKFNFFSSIFLSFLSLFFMFFL 316
Cdd:MTH00160  252 FLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLILNFLSFISLFGLILSSL 331


                  ....
gi 1778128448 317 FNSI 320
Cdd:MTH00160  332 LFLL 335
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-295 2.19e-26

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 106.51  E-value: 2.19e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMYSK--NFKSTFNFFIIQSISSLMLIMLMMIKNDFYFNTTFNLLLILVFSLKL 78
Cdd:MTH00144   19 LSLSSSHWLGVWVGLEINLIGFLPLLVYKKKssESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSMSLLLLGLCLKL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  79 GLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFnqiNNPTLMYTIISLTISSSLITTIMNYNETNFKKILTYS 158
Cdd:MTH00144   99 GLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFL---DLYWLAYLLCVISVLSALVGSIGGLNQTQVRALLAYS 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 159 STNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLmkFQFFNYNKINFIISLNFLIISALPPFLTFM 238
Cdd:MTH00144  176 SISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL--GSLKPSYKTGLSIISLLLSLGGLPPFLGFC 253

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1778128448 239 IKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNMMSMMKTKFFHSYNFNI 295
Cdd:MTH00144  254 SKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNS 310
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 1-294 1.16e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 95.89  E-value: 1.16e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMYSK--NFKSTFNFFIIQSISSLMLIM-LMMIKNDFYFNTTFNLLLILVFSLK 77
Cdd:MTH00197   13 FSLSSSNWFLVWIGMELNLIGFIPLLSQNKSitENEGAMKYFLFQEFGSALLLMgGSLSFSNLYLSLLSVVLVILGLLLK 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  78 LGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNqinnptLMYTIISLTISSSLITTIMNYNETNFKKILTY 157
Cdd:MTH00197   93 LGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSS------SFMGLLICSVLSSLIGGIGGMNQSNIRQLLAY 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 158 SSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNYNKINFIIsLNFLIISALPPFLTF 237
Cdd:MTH00197  167 SSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLG-LSFLSLGGLPPLSGF 245

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1778128448 238 MIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNMMSMMKTKFFHSYNFN 294
Cdd:MTH00197  246 FLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLL 302
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 2-279 3.54e-18

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 83.83  E-value: 3.54e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   2 SLFLSNYTHLWIIMEMNTLFFISLMSM--YSKNFKSTFNFFIIQSISSLMLIMLMMIKNDFY--------FNTTFNLLLI 71
Cdd:MTH00041   20 VISSNHWFLIWLGLELNTLSIIPILSSnfSPRSVEATIKYFLVQAFSAAILLNGALIQAWLSgswsingpLNTLSSIIIT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  72 LVFSLKLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNQINNptlmYTIISLTISSSLITTIMNYNETNF 151
Cdd:MTH00041  100 LALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNS----NILILCGILSVLVGGWGGLNQTQT 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 152 KKILTYSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNyNKINFIISLNFLIISAL 231
Cdd:MTH00041  176 RKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLN-PISAFLFILSILSLGGL 254

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1778128448 232 PPFLTFMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNM 279
Cdd:MTH00041  255 PPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSL 302
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-281 3.92e-17

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 80.59  E-value: 3.92e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMYSKN--FKSTFNFFIIQSISSLMLIMLMMIKNDFYFNTTFNLLLILVFS--L 76
Cdd:MTH00011   21 MALSSNNWLFLWMGMELNLLSFVPLMTSSKMNqeSEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLKNITALMLLVSlmL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  77 KLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNQINNPTlmytIISLTISSSLITTIMNYNETNFKKILT 156
Cdd:MTH00011  101 KLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPM----MTSMAAMSALAGGLGGMNQTQLRPLLA 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 157 YSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNYNkINFIISLNFLIISALPPFLT 236
Cdd:MTH00011  177 YSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQT-TSMSLFIMLLSLGGLPPFTG 255

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1778128448 237 FMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNIIVKLNMMS 281
Cdd:MTH00011  256 FMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLS 300
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-273 2.10e-16

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 78.47  E-value: 2.10e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSM--YSKNFKSTFNFFIIQSISSLMLI--------MLMMIKNDFYFNTTFNLLL 70
Cdd:MTH00200   19 LTFSSSHWFLIWLGLEINTLAIIPLLIKqhHPRKVEATTKYFIIQATASALLLfggllnawTSGQWGISEMLGPLSETLI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  71 ILVFSLKLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNQINNPTLMytiiSLTISSSLITTIMNYNETN 150
Cdd:MTH00200   99 LLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILL----LLGLLSVLVGGWGGLNQTQ 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 151 FKKILTYSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFQFFNyNKINFIISLNFLIISA 230
Cdd:MTH00200  175 LRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKN-PILSMLLGLTLLSLGG 253

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1778128448 231 LPPFLTFMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNI 273
Cdd:MTH00200  254 LPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRL 296
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 12-202 1.22e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 73.69  E-value: 1.22e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  12 WIIMEMNTLFFISLMSMY--SKNFKSTFNFFIIQSISSLMLImlmmikndfyFNTTFN------------------LLLI 71
Cdd:MTH00135   30 WMGLEINTLAIIPLMAQHhhPRAVEATTKYFLTQATAAAMIL----------FASTTNawltgqwdiqqmshplptTMIT 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  72 LVFSLKLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPL-LILnsffnQI--NNPTLMytiISLTISSSLITTIMNYNE 148
Cdd:MTH00135  100 LALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFaLIL-----QIapTNPTLL---ITLGLTSTLVGGWGGLNQ 171

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1778128448 149 TNFKKILTYSSTNHLSWMIFILMFDSSMFYLYFFIYFL--SMIFLCLIFNK-FNINS 202
Cdd:MTH00135  172 TQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIImtSSAFLTFKLNSsTKINT 228
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-274 2.06e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 72.96  E-value: 2.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMsMYSKNFKST---FNFFIIQSISSLMLIMLMMIKNDFY--------FNTTFNLL 69
Cdd:MTH00105   19 ITMISSHWLLAWIGLEMNMLAIIPIL-MKKHNPRSTeaaTKYFLTQATASMLLMMAIIINLMYSgqwtitklTNPTASTL 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  70 LILVFSLKLGLFPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNQINnptlMYTIISLTISSSLITTIMNYNET 149
Cdd:MTH00105   98 MTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSIN----PNLLLTLAILSILIGGWGGLNQT 173

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 150 NFKKILTYSSTNHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKFqffnYNK---INFIISLNFL 226
Cdd:MTH00105  174 QLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHT----WNKtplMTSLILLTLL 249

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 1778128448 227 IISALPPFLTFMIKINSIKVMIENYSLFSSLSLTLISIFTLIFYMNII 274
Cdd:MTH00105  250 SLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLI 297
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 12-201 5.32e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 65.71  E-value: 5.32e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  12 WIIMEMNTLFFISLMSM--YSKNFKSTFNFFIIQSISSLMLIMLMMIkNDFYF---------NTTFNLLLILVFSLKLGL 80
Cdd:MTH00070   30 WMGLEINTLAIIPLMTKthHPRATEAATKYFLTQASASALILFSSTI-NAWFTgewtimnmqTPLPTIMLTIALMMKLGI 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  81 FPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNQINnPTLMytiISLTISSSLITTIMNYNETNFKKILTYSST 160
Cdd:MTH00070  109 APFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLN-SNLL---IIMGLLSTLIGGWGGLNQTQLRKIMAYSSI 184

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1778128448 161 NHLSWMIFILMFDSSMFYLYFFIYFL---SMIFLCLIFNKFNIN 201
Cdd:MTH00070  185 AHLGWMIIILTFSPHLTLLNLLIYLImtsSMFLMLMNLNSTNIN 228
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 12-271 7.70e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 62.15  E-value: 7.70e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  12 WIIMEMNTLFFISLMSM--YSKNFKSTFNFFIIQSISSlMLIMLMMIKNDFY---------FNTTFNLLLILVFSLKLGL 80
Cdd:MTH00112   30 WTGLEINTLAIIPLISKphHPRATEAATKYFLTQAAAS-ALILFSSTTNAWNtgqwditqlTNPTSCTLLTLALAMKLGL 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  81 FPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFNQINNPTLMytiiSLTISSSLITTIMNYNETNFKKILTYSST 160
Cdd:MTH00112  109 APFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLL----TLAILSTLIGGWGGLNQTQLRKIMAFSSI 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 161 NHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMKfQFFNYNKINFIISLNFLIISALPPFLTFMIK 240
Cdd:MTH00112  185 AHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMT-SWTKSPTLNTTLMLTLLSLAGLPPLTGFMPK 263

                         250       260       270
                  ....*....|....*....|....*....|.
gi 1778128448 241 INSIKVMIENYSLFSSLSLTLISIFTLIFYM 271
Cdd:MTH00112  264 WLILQELTKQNMTPTATIMAMLSLLSLFFYL 294
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 1-288 1.30e-07

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 51.79  E-value: 1.30e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448   1 MSLFLSNYTHLWIIMEMNTLFFISLMSMySKNFKSTFNFFIIQSISSLMLIMLMmikndfyfnttFNLLLILVFSLKLGL 80
Cdd:MTH00091    6 LNFMSLNIFVWWSVFLLMTLLFVFLNKG-MGSYSSLFNYFVLQESLGLLFLLFS-----------FGYFQFLILMMKIGV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  81 FPFFFWPPLINMNLNWMLIFIMSTSQKLIPLLILNSFFnqinnptlMYTIISLTISSSLITTIMNYNETNFKKILTYSST 160
Cdd:MTH00091   74 APFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFF--------SKNFFFLLLFGLLICFFQMFLLKSYKNLLILSST 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 161 NHLSWMIFILMFDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDLMkfqffnynkinfiislNFLIISALPPFLTFMIK 240
Cdd:MTH00091  146 ESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWE----------------TLLVFMNLPFSVTFFVK 209

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1778128448 241 INSIKVMIENYSLFSSLSLTLISIFTL---IFYMNIIVKLNMMSMMKTKFF 288
Cdd:MTH00091  210 IFSLSEILKVLGFFLLFLLFLMFLSVLslsFWLVNLSTKLFLMLFKYNKGF 260
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 68-241 3.23e-07

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 50.77  E-value: 3.23e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448  68 LLLILVFSLKLGLFPFFFWPPLINMNLNWML-IFIMSTSQKL-IPLLILNSFFNQINNPTLMYTIISLTISSSLITTIMN 145
Cdd:pfam00361  86 LLILVGFLFKSAQVPFHTWLPDAYEGAPTPVsALLAATLVKAgGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAA 165

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1778128448 146 YNETNFKKILTYSSTNHLSWMIFILM------FDSSMFYLYFFIYFLSMIFLCLIFNKFNINSFFDL-MKFQFFNYNKIN 218
Cdd:pfam00361 166 LVQTDIKRLLAYSSISHMGYMLIALGagtiygIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIrDYGGLAKTMPIL 245

                         170       180
                  ....*....|....*....|....
gi 1778128448 219 FI-ISLNFLIISALPPFLTFMIKI 241
Cdd:pfam00361 246 ALvFLVAMLSLAGLPPTAGFLGKF 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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