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Conserved domains on  [gi|1798174256|ref|YP_009725255|]
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ORF10 protein [Severe acute respiratory syndrome coronavirus 2]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SARS-CoV-2_Orf10 cd21597
Severe acute respiratory syndrome coronavirus 2 Orf10; This model represents the Orf10 protein ...
 1-36 6.81e-12

Severe acute respiratory syndrome coronavirus 2 Orf10; This model represents the Orf10 protein of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV). SARS-CoV-2 causes the disease called "coronavirus disease 2019" (COVID-19). Orf10 appears to have no homologous proteins in SARS-CoV and other coronaviruses. It has been suggested that the genome sequence currently annotated as orf10 may not have a protein coding function in SARS-CoV-2, and instead may act, itself or as a precursor of other RNAs, in the regulation of gene expression, replication, or modulating cellular antiviral pathways (DOI:10.1101/2020.03.05.976167).


:

Pssm-ID: 394948  Cd Length: 36  Bit Score: 52.27  E-value: 6.81e-12
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 1798174256  1 MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFN 36
Cdd:cd21597    1 MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFN 36
 
Name Accession Description Interval E-value
SARS-CoV-2_Orf10 cd21597
Severe acute respiratory syndrome coronavirus 2 Orf10; This model represents the Orf10 protein ...
 1-36 6.81e-12

Severe acute respiratory syndrome coronavirus 2 Orf10; This model represents the Orf10 protein of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV). SARS-CoV-2 causes the disease called "coronavirus disease 2019" (COVID-19). Orf10 appears to have no homologous proteins in SARS-CoV and other coronaviruses. It has been suggested that the genome sequence currently annotated as orf10 may not have a protein coding function in SARS-CoV-2, and instead may act, itself or as a precursor of other RNAs, in the regulation of gene expression, replication, or modulating cellular antiviral pathways (DOI:10.1101/2020.03.05.976167).


Pssm-ID: 394948  Cd Length: 36  Bit Score: 52.27  E-value: 6.81e-12
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 1798174256  1 MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFN 36
Cdd:cd21597    1 MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFN 36
 
Name Accession Description Interval E-value
SARS-CoV-2_Orf10 cd21597
Severe acute respiratory syndrome coronavirus 2 Orf10; This model represents the Orf10 protein ...
 1-36 6.81e-12

Severe acute respiratory syndrome coronavirus 2 Orf10; This model represents the Orf10 protein of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as 2019 novel coronavirus (2019-nCoV). SARS-CoV-2 causes the disease called "coronavirus disease 2019" (COVID-19). Orf10 appears to have no homologous proteins in SARS-CoV and other coronaviruses. It has been suggested that the genome sequence currently annotated as orf10 may not have a protein coding function in SARS-CoV-2, and instead may act, itself or as a precursor of other RNAs, in the regulation of gene expression, replication, or modulating cellular antiviral pathways (DOI:10.1101/2020.03.05.976167).


Pssm-ID: 394948  Cd Length: 36  Bit Score: 52.27  E-value: 6.81e-12
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 1798174256  1 MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFN 36
Cdd:cd21597    1 MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFN 36
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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