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solute carrier family 12 member 3 isoform X2 [Mus musculus]
Protein Classification
solute carrier family 12 protein ( domain architecture ID 11489985 )
solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis, or human kidney-specific Na-K-Cl symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation
List of domain hits
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
57-1007
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1566.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 57 NT I D V VP AY EHY A NS ALP G E P RKV RP T L AD LH SF L - K EG S H L HA LA FDGRQ G RELTDGLVEDETGTNS EK S P GEP V R FGW 135
Cdd:TIGR00930 1 NT V D A VP RI EHY R NS EGQ G G P KRN RP S L EE LH DL L d K VV S L L GP LA DYTNN G QGMKEHEEAEDAEGTK EK P P AGA V K FGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 136 V K GV MIR C M LNIWGVIL Y LRL P WI TA QAGI V L TW LIILL SVM VT S ITGLS I SAI S TNG K VK S GG T Y F LISRSLGPE L GGS 215
Cdd:TIGR00930 81 V M GV LVP C L LNIWGVIL F LRL S WI VG QAGI G L SL LIILL CCC VT T ITGLS M SAI A TNG V VK G GG A Y Y LISRSLGPE F GGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 216 IGLIFAFANAV G VAM HT VGFAETV R DLL Q lacsptq E Y G TP I - VDPINDIRI I G V VTV T VLL A IS L AGMEWE S KAQVLF F 294
Cdd:TIGR00930 161 IGLIFAFANAV A VAM YV VGFAETV L DLL R ------- E N G SK I m VDPINDIRI Y G T VTV V VLL G IS F AGMEWE N KAQVLF L 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 295 LVIMV S FA N YL VGT L IPA S e DK AS KGF YSYHGD IF VQ N LV P DWR G ID G S FF GM F S IFFPS A TGILAGANISGDLKDP AV A 374
Cdd:TIGR00930 234 VIVLL S IL N IF VGT I IPA F - DK PA KGF FGLGNE IF SE N FI P GIP G PE G G FF SL F G IFFPS V TGILAGANISGDLKDP QK A 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 375 IPKGTL M AI FW TT IS YL AISATI G S CVVRDA S GD V NDT MTPG pgp C EGL AC gygwn F T EC SQQ r S C R YGL I N YY Q T MS M V 454
Cdd:TIGR00930 313 IPKGTL L AI LT TT VV YL GSVVLF G A CVVRDA T GD K NDT LVTN --- C TSA AC ----- F S EC AHN - T C S YGL M N NL Q V MS L V 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 455 S A F A PLITAGIF G ATLSSALA C LVSA AKV FQ C LC E D QL YP LIG FFGKGYGKN R EP V R G YLL AYA IA VA FI I IAELNTIAP 534
Cdd:TIGR00930 384 S P F P PLITAGIF S ATLSSALA S LVSA PRL FQ A LC K D NI YP FLQ FFGKGYGKN G EP L R A YLL TAF IA EG FI L IAELNTIAP 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 535 IISNFFL C SYALINFSCFHAS ITN SPGWRP S F R YY SK W AA L F GA VISVV IMFL LT WWAAL I A IGVV LFL LL YV I YKKP E V 614
Cdd:TIGR00930 464 IISNFFL A SYALINFSCFHAS LLR SPGWRP R F K YY HW W LS L L GA SLCCA IMFL IS WWAAL V A MVIA LFL YK YV T YKKP D V 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 615 NWGSS V QA G SY N LAL SYSVG L N EVEDH I KN Y RPQCLVLTGPP NF RPAL V DF V S T FT QNLS LMICG H V LI GP GKQR V P E LR 694
Cdd:TIGR00930 544 NWGSS T QA L SY S LAL YSLLR L E EVEDH V KN W RPQCLVLTGPP VC RPAL L DF A S Q FT KGKG LMICG S V IQ GP RLEC V K E AQ 623
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 695 LIASGHTK WL N K R K I KAFY SD V I A E DLR S GV QI L M QASGLGRMKPN I LV V G F K RN W QS A H P ATV E D YIG VL HDAFD FNYG 774
Cdd:TIGR00930 624 AAEAKIQT WL E K N K V KAFY AV V V A D DLR E GV RH L I QASGLGRMKPN T LV M G Y K KD W RQ A E P RAW E T YIG II HDAFD AHLA 703
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 775 V C V M R MR EGL NV S e A LQ TH ----------------- TTPEALIQEEQ AST I FQ SE QGK K TID IY WL F DDGGLTLL I PYLL 837
Cdd:TIGR00930 704 V V V V R NS EGL PI S - V LQ VQ eelendcsedsielndg KISTQPDMHLE AST Q FQ KK QGK G TID VW WL V DDGGLTLL L PYLL 782
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 838 HR KK R W G KCKIR V FVG G Q - IN R MDE E R K AIIS LL S KFR LGFHEVH VL P DIN Q KPQ A E HTKR FE D MI A PFRL NDGF KD EAT 916
Cdd:TIGR00930 783 TT KK V W K KCKIR I FVG A Q k DD R SEQ E K K DMAT LL Y KFR IDAEVIV VL M DIN A KPQ T E SMEA FE E MI R PFRL HKTE KD REA 862
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 917 VT - E M RRDC PWKI S D E E INK N RI KS L RQVRL S E I LL D YSRDAAL II L T LP IG RKG KC P SS LYMAWLE T LS Q DL r PPVLL I 995
Cdd:TIGR00930 863 KD p K M TWTK PWKI T D A E LQS N VR KS Y RQVRL N E L LL E YSRDAAL VV L S LP VP RKG SI P DE LYMAWLE V LS E DL - PPVLL V 941
970
....*....|..
gi 1039786896 996 RGN QE NVLTFY C 1007
Cdd:TIGR00930 942 RGN HR NVLTFY S 953
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
57-1007
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1566.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 57 NT I D V VP AY EHY A NS ALP G E P RKV RP T L AD LH SF L - K EG S H L HA LA FDGRQ G RELTDGLVEDETGTNS EK S P GEP V R FGW 135
Cdd:TIGR00930 1 NT V D A VP RI EHY R NS EGQ G G P KRN RP S L EE LH DL L d K VV S L L GP LA DYTNN G QGMKEHEEAEDAEGTK EK P P AGA V K FGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 136 V K GV MIR C M LNIWGVIL Y LRL P WI TA QAGI V L TW LIILL SVM VT S ITGLS I SAI S TNG K VK S GG T Y F LISRSLGPE L GGS 215
Cdd:TIGR00930 81 V M GV LVP C L LNIWGVIL F LRL S WI VG QAGI G L SL LIILL CCC VT T ITGLS M SAI A TNG V VK G GG A Y Y LISRSLGPE F GGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 216 IGLIFAFANAV G VAM HT VGFAETV R DLL Q lacsptq E Y G TP I - VDPINDIRI I G V VTV T VLL A IS L AGMEWE S KAQVLF F 294
Cdd:TIGR00930 161 IGLIFAFANAV A VAM YV VGFAETV L DLL R ------- E N G SK I m VDPINDIRI Y G T VTV V VLL G IS F AGMEWE N KAQVLF L 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 295 LVIMV S FA N YL VGT L IPA S e DK AS KGF YSYHGD IF VQ N LV P DWR G ID G S FF GM F S IFFPS A TGILAGANISGDLKDP AV A 374
Cdd:TIGR00930 234 VIVLL S IL N IF VGT I IPA F - DK PA KGF FGLGNE IF SE N FI P GIP G PE G G FF SL F G IFFPS V TGILAGANISGDLKDP QK A 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 375 IPKGTL M AI FW TT IS YL AISATI G S CVVRDA S GD V NDT MTPG pgp C EGL AC gygwn F T EC SQQ r S C R YGL I N YY Q T MS M V 454
Cdd:TIGR00930 313 IPKGTL L AI LT TT VV YL GSVVLF G A CVVRDA T GD K NDT LVTN --- C TSA AC ----- F S EC AHN - T C S YGL M N NL Q V MS L V 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 455 S A F A PLITAGIF G ATLSSALA C LVSA AKV FQ C LC E D QL YP LIG FFGKGYGKN R EP V R G YLL AYA IA VA FI I IAELNTIAP 534
Cdd:TIGR00930 384 S P F P PLITAGIF S ATLSSALA S LVSA PRL FQ A LC K D NI YP FLQ FFGKGYGKN G EP L R A YLL TAF IA EG FI L IAELNTIAP 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 535 IISNFFL C SYALINFSCFHAS ITN SPGWRP S F R YY SK W AA L F GA VISVV IMFL LT WWAAL I A IGVV LFL LL YV I YKKP E V 614
Cdd:TIGR00930 464 IISNFFL A SYALINFSCFHAS LLR SPGWRP R F K YY HW W LS L L GA SLCCA IMFL IS WWAAL V A MVIA LFL YK YV T YKKP D V 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 615 NWGSS V QA G SY N LAL SYSVG L N EVEDH I KN Y RPQCLVLTGPP NF RPAL V DF V S T FT QNLS LMICG H V LI GP GKQR V P E LR 694
Cdd:TIGR00930 544 NWGSS T QA L SY S LAL YSLLR L E EVEDH V KN W RPQCLVLTGPP VC RPAL L DF A S Q FT KGKG LMICG S V IQ GP RLEC V K E AQ 623
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 695 LIASGHTK WL N K R K I KAFY SD V I A E DLR S GV QI L M QASGLGRMKPN I LV V G F K RN W QS A H P ATV E D YIG VL HDAFD FNYG 774
Cdd:TIGR00930 624 AAEAKIQT WL E K N K V KAFY AV V V A D DLR E GV RH L I QASGLGRMKPN T LV M G Y K KD W RQ A E P RAW E T YIG II HDAFD AHLA 703
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 775 V C V M R MR EGL NV S e A LQ TH ----------------- TTPEALIQEEQ AST I FQ SE QGK K TID IY WL F DDGGLTLL I PYLL 837
Cdd:TIGR00930 704 V V V V R NS EGL PI S - V LQ VQ eelendcsedsielndg KISTQPDMHLE AST Q FQ KK QGK G TID VW WL V DDGGLTLL L PYLL 782
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 838 HR KK R W G KCKIR V FVG G Q - IN R MDE E R K AIIS LL S KFR LGFHEVH VL P DIN Q KPQ A E HTKR FE D MI A PFRL NDGF KD EAT 916
Cdd:TIGR00930 783 TT KK V W K KCKIR I FVG A Q k DD R SEQ E K K DMAT LL Y KFR IDAEVIV VL M DIN A KPQ T E SMEA FE E MI R PFRL HKTE KD REA 862
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 917 VT - E M RRDC PWKI S D E E INK N RI KS L RQVRL S E I LL D YSRDAAL II L T LP IG RKG KC P SS LYMAWLE T LS Q DL r PPVLL I 995
Cdd:TIGR00930 863 KD p K M TWTK PWKI T D A E LQS N VR KS Y RQVRL N E L LL E YSRDAAL VV L S LP VP RKG SI P DE LYMAWLE V LS E DL - PPVLL V 941
970
....*....|..
gi 1039786896 996 RGN QE NVLTFY C 1007
Cdd:TIGR00930 942 RGN HR NVLTFY S 953
SLC12
pfam03522 Solute carrier family 12;
659-1007
1.46e-168
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 499.45
E-value: 1.46e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 659 RPALVDF VSTF T Q N L SLMICGHV LI G PGK Q RVPELR l IASGH t K WL N KRKIKAFY SD V IAED LR S G V Q I L M QASGLG RM K 738
Cdd:pfam03522 1 RPALVDF AHLI T K N V SLMICGHV VK G RLS Q KLRSEL - QKKAY - R WL R KRKIKAFY AL V DGDN LR E G A Q A L L QASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 739 PNIL VV G F K RN W QSAHPATV E D Y IG V L HDAFD FN Y G V CVM R MR EGL N VS EA LQ - TH T TPEA L IQ E EQA S ----------- 806
Cdd:pfam03522 79 PNIL LM G Y K SD W RTCDKEEL E E Y FN V I HDAFD LQ Y A V AIL R LP EGL D VS HL LQ d QD T EELG L GD E TNS S yaeqsseeqst 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 807 --------------------------------------------------------------- T I FQ SE Q G K K TID IY WL 823
Cdd:pfam03522 159 snskqdddksklskkdsnlslspdkstknpsgkdssksdklkkkspsiilrtasnekeilnni T Q FQ KK Q K K G TID VW WL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 824 F DDGGLTLL I PY L L HRKKR W GK CK I RVF VG G - QINRMD EE RKAII SLLSKFR LGFHEVH V L PDI NQ KP QA E HT K R F EDM I 902
Cdd:pfam03522 239 Y DDGGLTLL L PY I L STRSK W SD CK L RVF AL G n RKDELE EE QRNMA SLLSKFR IDYSDLT V I PDI TK KP KK E TK K F F DEL I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 903 A PFRL NDGF K D E ATV temrrdcp W KI S D E E INKNRI K SL RQ V RL S E I LL DY S R DA A LI IL TLP IG RKG KCPSS LYMAWLE 982
Cdd:pfam03522 319 E PFRL HEDD K E E ESA -------- E KI T D S E LEALKE K TN RQ L RL R E L LL EH S S DA N LI VM TLP MP RKG TVSAP LYMAWLE 390
410 420
....*....|....*....|....*
gi 1039786896 983 TL SQ DL r PP V LL I RGNQ EN VLTFY C 1007
Cdd:pfam03522 391 TL TK DL - PP F LL V RGNQ TS VLTFY S 414
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
156-611
5.95e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 133.10
E-value: 5.95e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 156 LP WIT A QAGIVLTW L II L LSVMVTSITG LS ISAISTN g KVKS GG T Y FLIS R S LGP E LG GSI G LIFAFANAVG VA MHT V G F 235
Cdd:COG0531 34 LP GLA A GLAGPAAI L AW L IAGLLALLVA LS YAELASA - FPRA GG A Y TYAR R A LGP L LG FLA G WALLLSYVLA VA AVA V A F 112
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 236 AETVRD L L qlacsptqeygtpivd P INDIRI I GV V TVTV L LAIS L A G MEWES K AQVLFFLVIMVSFANYL V G tlipased 315
Cdd:COG0531 113 GGYLSS L F ---------------- P AGGSVL I AL V LILL L TLLN L R G VKESA K VNNILTVLKLLVLLLFI V V -------- 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 316 kask G FYSYHGDI F v QNLV P DWR G ID G s FFGMFSIF F PSA TG IL A G AN ISGDL K D P AVA IP KGTLMAIFWTTIS Y LAI S A 395
Cdd:COG0531 169 ---- G LFAFDPAN F - TPFL P AGG G LS G - VLAALALA F FAF TG FE A I AN LAEEA K N P KRN IP RAIILSLLIVGVL Y ILV S L 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 396 TIGSC V VR D ASGDVNDTM tpgpgpceglacgygwnftecsqqrscrygliny YQTMSM V -- SAF A P LI TA G IFGAT L SSA 473
Cdd:COG0531 243 ALTGV V PY D ELAASGAPL ---------------------------------- ADAAEA V fg PWG A I LI AL G ALLSL L GAL 288
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 474 L A CLVS A AKVFQCLCE D Q L Y P li GF F G K GYGKNRE PV RGY LL AY -- A IAVAFIII A ELNTI A PII S NFF L CS Y A L INFSC 551
Cdd:COG0531 289 N A SILG A SRLLYAMAR D G L L P -- KV F A K VHPRFGT PV NAI LL TG vi A LLLLLLGA A SFTAL A SLA S VGV L LA Y L L VALAV 366
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039786896 552 FHASITNSPGW RP s FR YYSKWAALF G AVISVVIMF LL TWW A A LI AIGVVLF - LLLY VI Y KK 611
Cdd:COG0531 367 IVLRRRRPDLP RP - FR VPLPLIPIL G ILLCLFLLY LL GPG A L LI GLVLLAI g LLLY LL Y RR 426
Name
Accession
Description
Interval
E-value
2a30
TIGR00930 K-Cl cotransporter; [Transport and binding proteins, Other]
57-1007
0e+00
K-Cl cotransporter; [Transport and binding proteins, Other]
Pssm-ID: 273347 [Multi-domain]
Cd Length: 953
Bit Score: 1566.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 57 NT I D V VP AY EHY A NS ALP G E P RKV RP T L AD LH SF L - K EG S H L HA LA FDGRQ G RELTDGLVEDETGTNS EK S P GEP V R FGW 135
Cdd:TIGR00930 1 NT V D A VP RI EHY R NS EGQ G G P KRN RP S L EE LH DL L d K VV S L L GP LA DYTNN G QGMKEHEEAEDAEGTK EK P P AGA V K FGW 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 136 V K GV MIR C M LNIWGVIL Y LRL P WI TA QAGI V L TW LIILL SVM VT S ITGLS I SAI S TNG K VK S GG T Y F LISRSLGPE L GGS 215
Cdd:TIGR00930 81 V M GV LVP C L LNIWGVIL F LRL S WI VG QAGI G L SL LIILL CCC VT T ITGLS M SAI A TNG V VK G GG A Y Y LISRSLGPE F GGS 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 216 IGLIFAFANAV G VAM HT VGFAETV R DLL Q lacsptq E Y G TP I - VDPINDIRI I G V VTV T VLL A IS L AGMEWE S KAQVLF F 294
Cdd:TIGR00930 161 IGLIFAFANAV A VAM YV VGFAETV L DLL R ------- E N G SK I m VDPINDIRI Y G T VTV V VLL G IS F AGMEWE N KAQVLF L 233
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 295 LVIMV S FA N YL VGT L IPA S e DK AS KGF YSYHGD IF VQ N LV P DWR G ID G S FF GM F S IFFPS A TGILAGANISGDLKDP AV A 374
Cdd:TIGR00930 234 VIVLL S IL N IF VGT I IPA F - DK PA KGF FGLGNE IF SE N FI P GIP G PE G G FF SL F G IFFPS V TGILAGANISGDLKDP QK A 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 375 IPKGTL M AI FW TT IS YL AISATI G S CVVRDA S GD V NDT MTPG pgp C EGL AC gygwn F T EC SQQ r S C R YGL I N YY Q T MS M V 454
Cdd:TIGR00930 313 IPKGTL L AI LT TT VV YL GSVVLF G A CVVRDA T GD K NDT LVTN --- C TSA AC ----- F S EC AHN - T C S YGL M N NL Q V MS L V 383
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 455 S A F A PLITAGIF G ATLSSALA C LVSA AKV FQ C LC E D QL YP LIG FFGKGYGKN R EP V R G YLL AYA IA VA FI I IAELNTIAP 534
Cdd:TIGR00930 384 S P F P PLITAGIF S ATLSSALA S LVSA PRL FQ A LC K D NI YP FLQ FFGKGYGKN G EP L R A YLL TAF IA EG FI L IAELNTIAP 463
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 535 IISNFFL C SYALINFSCFHAS ITN SPGWRP S F R YY SK W AA L F GA VISVV IMFL LT WWAAL I A IGVV LFL LL YV I YKKP E V 614
Cdd:TIGR00930 464 IISNFFL A SYALINFSCFHAS LLR SPGWRP R F K YY HW W LS L L GA SLCCA IMFL IS WWAAL V A MVIA LFL YK YV T YKKP D V 543
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 615 NWGSS V QA G SY N LAL SYSVG L N EVEDH I KN Y RPQCLVLTGPP NF RPAL V DF V S T FT QNLS LMICG H V LI GP GKQR V P E LR 694
Cdd:TIGR00930 544 NWGSS T QA L SY S LAL YSLLR L E EVEDH V KN W RPQCLVLTGPP VC RPAL L DF A S Q FT KGKG LMICG S V IQ GP RLEC V K E AQ 623
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 695 LIASGHTK WL N K R K I KAFY SD V I A E DLR S GV QI L M QASGLGRMKPN I LV V G F K RN W QS A H P ATV E D YIG VL HDAFD FNYG 774
Cdd:TIGR00930 624 AAEAKIQT WL E K N K V KAFY AV V V A D DLR E GV RH L I QASGLGRMKPN T LV M G Y K KD W RQ A E P RAW E T YIG II HDAFD AHLA 703
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 775 V C V M R MR EGL NV S e A LQ TH ----------------- TTPEALIQEEQ AST I FQ SE QGK K TID IY WL F DDGGLTLL I PYLL 837
Cdd:TIGR00930 704 V V V V R NS EGL PI S - V LQ VQ eelendcsedsielndg KISTQPDMHLE AST Q FQ KK QGK G TID VW WL V DDGGLTLL L PYLL 782
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 838 HR KK R W G KCKIR V FVG G Q - IN R MDE E R K AIIS LL S KFR LGFHEVH VL P DIN Q KPQ A E HTKR FE D MI A PFRL NDGF KD EAT 916
Cdd:TIGR00930 783 TT KK V W K KCKIR I FVG A Q k DD R SEQ E K K DMAT LL Y KFR IDAEVIV VL M DIN A KPQ T E SMEA FE E MI R PFRL HKTE KD REA 862
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 917 VT - E M RRDC PWKI S D E E INK N RI KS L RQVRL S E I LL D YSRDAAL II L T LP IG RKG KC P SS LYMAWLE T LS Q DL r PPVLL I 995
Cdd:TIGR00930 863 KD p K M TWTK PWKI T D A E LQS N VR KS Y RQVRL N E L LL E YSRDAAL VV L S LP VP RKG SI P DE LYMAWLE V LS E DL - PPVLL V 941
970
....*....|..
gi 1039786896 996 RGN QE NVLTFY C 1007
Cdd:TIGR00930 942 RGN HR NVLTFY S 953
SLC12
pfam03522 Solute carrier family 12;
659-1007
1.46e-168
Solute carrier family 12;
Pssm-ID: 460955
Cd Length: 414
Bit Score: 499.45
E-value: 1.46e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 659 RPALVDF VSTF T Q N L SLMICGHV LI G PGK Q RVPELR l IASGH t K WL N KRKIKAFY SD V IAED LR S G V Q I L M QASGLG RM K 738
Cdd:pfam03522 1 RPALVDF AHLI T K N V SLMICGHV VK G RLS Q KLRSEL - QKKAY - R WL R KRKIKAFY AL V DGDN LR E G A Q A L L QASGLG KL K 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 739 PNIL VV G F K RN W QSAHPATV E D Y IG V L HDAFD FN Y G V CVM R MR EGL N VS EA LQ - TH T TPEA L IQ E EQA S ----------- 806
Cdd:pfam03522 79 PNIL LM G Y K SD W RTCDKEEL E E Y FN V I HDAFD LQ Y A V AIL R LP EGL D VS HL LQ d QD T EELG L GD E TNS S yaeqsseeqst 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 807 --------------------------------------------------------------- T I FQ SE Q G K K TID IY WL 823
Cdd:pfam03522 159 snskqdddksklskkdsnlslspdkstknpsgkdssksdklkkkspsiilrtasnekeilnni T Q FQ KK Q K K G TID VW WL 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 824 F DDGGLTLL I PY L L HRKKR W GK CK I RVF VG G - QINRMD EE RKAII SLLSKFR LGFHEVH V L PDI NQ KP QA E HT K R F EDM I 902
Cdd:pfam03522 239 Y DDGGLTLL L PY I L STRSK W SD CK L RVF AL G n RKDELE EE QRNMA SLLSKFR IDYSDLT V I PDI TK KP KK E TK K F F DEL I 318
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 903 A PFRL NDGF K D E ATV temrrdcp W KI S D E E INKNRI K SL RQ V RL S E I LL DY S R DA A LI IL TLP IG RKG KCPSS LYMAWLE 982
Cdd:pfam03522 319 E PFRL HEDD K E E ESA -------- E KI T D S E LEALKE K TN RQ L RL R E L LL EH S S DA N LI VM TLP MP RKG TVSAP LYMAWLE 390
410 420
....*....|....*....|....*
gi 1039786896 983 TL SQ DL r PP V LL I RGNQ EN VLTFY C 1007
Cdd:pfam03522 391 TL TK DL - PP F LL V RGNQ TS VLTFY S 414
AA_permease
pfam00324 Amino acid permease;
138-650
2.03e-117
Amino acid permease;
Pssm-ID: 366028 [Multi-domain]
Cd Length: 467
Bit Score: 368.57
E-value: 2.03e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 138 G V MIRCMLNIW G VI L YLRLPWITA QAG IVLTW L II L L S VM V TSITG LS ISA ISTNG K V k SGG T Y FLI SR S LGP E LG GSI G 217
Cdd:pfam00324 1 H V QMIALGGVI G TG L FVGSGSVLG QAG PAGAL L GY L I S GV V IFLVM LS LGE ISTNG P V - SGG F Y TYA SR F LGP S LG FAT G 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 218 L ------ I FAF A NAVGV A MHTVG F A E T V R D LLQ L A csptqeygtpivdpindir II G V V TVTV L LA I S L A G ME W ESK A QV 291
Cdd:pfam00324 80 W nywlsw I TVL A LELTA A SILIQ F W E L V P D IPY L W ------------------- VW G A V FLVL L TI I N L V G VK W YGE A EF 140
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 292 L F F L VIMVSFANYLVGTL I PA S EDKASK G -- F YSYHGDIFVQ N LV P DW rgi DGS F FGM F S I F F PSA TGI LAGANIS G DL K 369
Cdd:pfam00324 141 W F A L IKIIAIIGFIIVGI I LL S GGNPND G ai F RYLGDNGGKN N FP P GF --- GKG F ISV F V I A F FAF TGI ELVGIAA G EV K 217
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 370 D P AVA IPK GT L MA I FWT TI S Y LAISAT IG SC V VRDAS G DV ND TMTP gpgpceglacgygwnftecsqqrscr YGLINYYQ 449
Cdd:pfam00324 218 N P EKS IPK AI L QV I WRI TI F Y ILSLLA IG LL V PWNDP G LL ND SASA -------------------------- ASPFVIFF 271
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 450 TMSMV S AF APLI T A G I FG A T LS S A LAC L V S AAKVFQC L CE D Q L Y P lig F F G K GYG K NRE P V R GY L LAYA I AVAFIII A E L 529
Cdd:pfam00324 272 KFLGI S GL APLI N A V I LT A A LS A A NSS L Y S GSRMLYS L AR D G L A P --- K F L K KVD K RGV P L R AI L VSMV I SLLALLL A S L 348
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 530 N TI ap I IS NF F L CSYA L INFSCFHASITNSPGW R PS F R Y YSKWAALFGAVISVVIMFLLTWW AA L I A I GVVL FL LLYVIY 609
Cdd:pfam00324 349 N PA -- I VF NF L L AISG L SGLIVWGLISLSHLRF R KA F K Y QGRSIDELPFKAPLGPLGVILGL AA I I I I LIIQ FL YAFLPV 426
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 1039786896 610 KKPEV NWG SSVQ A GS Y NLA L SYSVG L NE V ED H I KN YR PQ C L 650
Cdd:pfam00324 427 PGGPK NWG AGSF A AA Y LIV L LFLII L IG V KL H V KN WK PQ L L 467
PotE
COG0531 Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
156-611
5.95e-33
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
Pssm-ID: 440297 [Multi-domain]
Cd Length: 438
Bit Score: 133.10
E-value: 5.95e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 156 LP WIT A QAGIVLTW L II L LSVMVTSITG LS ISAISTN g KVKS GG T Y FLIS R S LGP E LG GSI G LIFAFANAVG VA MHT V G F 235
Cdd:COG0531 34 LP GLA A GLAGPAAI L AW L IAGLLALLVA LS YAELASA - FPRA GG A Y TYAR R A LGP L LG FLA G WALLLSYVLA VA AVA V A F 112
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 236 AETVRD L L qlacsptqeygtpivd P INDIRI I GV V TVTV L LAIS L A G MEWES K AQVLFFLVIMVSFANYL V G tlipased 315
Cdd:COG0531 113 GGYLSS L F ---------------- P AGGSVL I AL V LILL L TLLN L R G VKESA K VNNILTVLKLLVLLLFI V V -------- 168
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 316 kask G FYSYHGDI F v QNLV P DWR G ID G s FFGMFSIF F PSA TG IL A G AN ISGDL K D P AVA IP KGTLMAIFWTTIS Y LAI S A 395
Cdd:COG0531 169 ---- G LFAFDPAN F - TPFL P AGG G LS G - VLAALALA F FAF TG FE A I AN LAEEA K N P KRN IP RAIILSLLIVGVL Y ILV S L 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 396 TIGSC V VR D ASGDVNDTM tpgpgpceglacgygwnftecsqqrscrygliny YQTMSM V -- SAF A P LI TA G IFGAT L SSA 473
Cdd:COG0531 243 ALTGV V PY D ELAASGAPL ---------------------------------- ADAAEA V fg PWG A I LI AL G ALLSL L GAL 288
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 474 L A CLVS A AKVFQCLCE D Q L Y P li GF F G K GYGKNRE PV RGY LL AY -- A IAVAFIII A ELNTI A PII S NFF L CS Y A L INFSC 551
Cdd:COG0531 289 N A SILG A SRLLYAMAR D G L L P -- KV F A K VHPRFGT PV NAI LL TG vi A LLLLLLGA A SFTAL A SLA S VGV L LA Y L L VALAV 366
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039786896 552 FHASITNSPGW RP s FR YYSKWAALF G AVISVVIMF LL TWW A A LI AIGVVLF - LLLY VI Y KK 611
Cdd:COG0531 367 IVLRRRRPDLP RP - FR VPLPLIPIL G ILLCLFLLY LL GPG A L LI GLVLLAI g LLLY LL Y RR 426
AA_permease_N
pfam08403 Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid ...
43-113
7.99e-33
Amino acid permease N-terminal; This domain is found to the N-terminus of the amino acid permease domain (pfam00324) in metazoan Na-K-Cl cotransporters.
Pssm-ID: 429977
Cd Length: 70
Bit Score: 121.39
E-value: 7.99e-33
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039786896 43 L THGST L Y MR TFG Y NT I D V VP AYEH Y A N SALPGEPR K V RP T LA D LHS F LK EG S H L h A L A FDGRQ G R E LT DG 113
Cdd:pfam08403 1 D THGST Y Y LQ TFG H NT L D A VP RIDF Y R N TGSVSGVK K S RP S LA E LHS Q LK KN S A L - A V A EGSVD G V E NG DG 70
AA_permease_2
pfam13520 Amino acid permease;
163-608
9.39e-12
Amino acid permease;
Pssm-ID: 404414 [Multi-domain]
Cd Length: 427
Bit Score: 68.49
E-value: 9.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 163 A G IVLTWLIILLSVMVT S ITGLSIS A ISTNGKVK SGG T Y FLISRSL G PELGGSI G LIFA FA NAV G V A MHTVGF A ET vrd L 242
Cdd:pfam13520 27 S G GPALIVWGWIAAIIF S LAVGLVY A ELSSALPR SGG I Y VYLENAF G KFVAFLA G WSNW FA YVL G L A SSASVA A SY --- L 103
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 243 L QLA csptqey G TPI V DPINDIRI I GVVTVTVLLA I SLA G MEWES K A Q VLFFLVIMVSFANYLVGTLIPA sedk A SK G FY 322
Cdd:pfam13520 104 L SAL ------- G PDL V PTTWLTYG I AIAILIIFAI I NIR G VRESA K I Q NILGILKLLLPLILIIILGLVT ---- A DG G GF 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 323 SYHGDIFVQNLVPD W rgi D G S F F G MFSIFF p S A TG ILAG AN I S GDL K DPA V ai PK GTLMAIFWTTIS Y LAISATIGSC V V 402
Cdd:pfam13520 173 NLLSGEWHTFFPDG W --- P G V F A G FLGVLW - S F TG FESA AN V S EEV K KRN V -- PK AIFIGVIIVGVL Y ILVNIAFFGV V P 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 403 R D ASGDVNDTMTPGP gpceglacgygwnftecsqqrscryglin YYQTMSMVSAF A PLITAGIFGAT L SSALACL V S A AK 482
Cdd:pfam13520 247 D D EIALSSGLGQVAA ----------------------------- LLFQAVGGKWG A IIVVILLALSL L GAVNTAI V G A SR 297
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039786896 483 VFQC L CE D QLY P LIG FF G K g YG K NRE P V R GYL L AY ----- AIAVAFIII A EL N TIAPIISNFF L C SY A L INFSCFHASIT 557
Cdd:pfam13520 298 LLYA L AR D GVL P FSR FF A K - VN K FGS P I R AII L TA ilsli LLLLFLLSP A AY N ALLSLSAYGY L L SY L L PIIGLLILRKK 376
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 1039786896 558 NSPGW R psf RYYSKWA A L FG AVI S VVIMFL L TWWAALI A I G VV L FLLLYV I 608
Cdd:pfam13520 377 RPDLG R --- IPGRWPV A I FG ILF S LFLIVA L FFPPVGP A T G SS L NYAIIL I 424
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
