|
Name |
Accession |
Description |
Interval |
E-value |
| Map |
COG0024 |
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis]; |
61-304 |
4.04e-85 |
|
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439795 [Multi-domain] Cd Length: 250 Bit Score: 256.09 E-value: 4.04e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 61 KPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHR 139
Cdd:COG0024 4 KTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLEL-DRIAEEFIRdHGAIPAFLGYYGFPKSICTSVNEVVVHGIPSDR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 140 ALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVR 219
Cdd:COG0024 83 VLKDGDIVNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNRLGDIGHAIQSYAESNGYSVVR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 220 AYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHR 299
Cdd:COG0024 163 EFVGHGIGREMHEEPQVPNYGRPGRGPRLKPGMVLAIEPMINAGTPEVKVLDDGWTVVTKDGSLSAQFEHTVAVTEDGPE 242
|
....*
gi 1127359753 300 LLSAL 304
Cdd:COG0024 243 ILTLP 247
|
|
| PRK05716 |
PRK05716 |
methionine aminopeptidase; Validated |
59-302 |
1.29e-59 |
|
methionine aminopeptidase; Validated
Pssm-ID: 235576 [Multi-domain] Cd Length: 252 Bit Score: 190.73 E-value: 1.29e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 59 SQKPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLHGIPS 137
Cdd:PRK05716 4 TIKTPEEIEKMRVAGRLAAEVLDEIEPHVKPGVTTKEL-DRIAEEYIRdQGAIPAPLGYHGFPKSICTSVNEVVCHGIPS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 138 HRALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAV 217
Cdd:PRK05716 83 DKVLKEGDIVNIDVTVIKDGYHGDTSRTFGVGEISPEDKRLCEVTKEALYLGIAAVKPGARLGDIGHAIQKYAEAEGFSV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 218 VRAYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADG 297
Cdd:PRK05716 163 VREYCGHGIGRKFHEEPQIPHYGAPGDGPVLKEGMVFTIEPMINAGKREVKTLKDGWTVVTKDGSLSAQYEHTVAVTEDG 242
|
....*
gi 1127359753 298 HRLLS 302
Cdd:PRK05716 243 PEILT 247
|
|
| MetAP1 |
cd01086 |
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
66-302 |
2.39e-58 |
|
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238519 [Multi-domain] Cd Length: 238 Bit Score: 187.32 E-value: 2.39e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 66 LEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHRALKNG 144
Cdd:cd01086 1 IEGMREAGRIVAEVLDELAKAIKPGVTTKEL-DQIAHEFIEeHGAYPAPLGYYGFPKSICTSVNEVVCHGIPDDRVLKDG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 145 DLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVRAYTGY 224
Cdd:cd01086 80 DIVNIDVGVELDGYHGDSARTFIVGEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKNGYSVVREFGGH 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1127359753 225 GMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHRLLS 302
Cdd:cd01086 160 GIGRKFHEEPQIPNYGRPGTGPKLKPGMVFTIEPMINLGTYEVVTLPDGWTVVTKDGSLSAQFEHTVLITEDGPEILT 237
|
|
| met_pdase_I |
TIGR00500 |
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. ... |
61-304 |
2.00e-47 |
|
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. This model describes type I. The role of this protein in general is to produce the mature form of cytosolic proteins by removing the N-terminal methionine. [Protein fate, Protein modification and repair]
Pssm-ID: 129591 [Multi-domain] Cd Length: 247 Bit Score: 159.44 E-value: 2.00e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 61 KPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVK-EAFRHDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHR 139
Cdd:TIGR00500 4 KSPDEIEKIRKAGRLAAEVLEELEREVKPGVSTKEL-DRIAKdFIEKHGAKPAFLGYYGFPGSVCISVNEVVIHGIPDKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 140 ALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVR 219
Cdd:TIGR00500 83 VLKDGDIVNIDVGVIYDGYHGDTAKTFLVGKISPEAEKLLECTEESLYKAIEEAKPGNRIGEIGAAIQKYAEAKGFSVVR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 220 AYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHR 299
Cdd:TIGR00500 163 EYCGHGIGRKFHEEPQIPNYGKKFTNVRLKEGMVFTIEPMVNTGTEEITTAADGWTVKTKDGSLSAQFEHTIVITDNGPE 242
|
....*
gi 1127359753 300 LLSAL 304
Cdd:TIGR00500 243 ILTER 247
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
70-295 |
7.45e-26 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 101.93 E-value: 7.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 70 RRIAPILSEVMRDVGRSVVAGDTTRDVADRLVKEAFRHdllpAMLGYNAFPAMAATSVNEEVLHGIPSHRALKNGDLLKL 149
Cdd:pfam00557 4 RKAARIAAAALEAALAAIRPGVTERELAAELEAARLRR----GGARGPAFPPIVASGPNAAIPHYIPNDRVLKPGDLVLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 150 QFGVVSGAAFAA-QGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGL-AVVRAYTGYGMG 227
Cdd:pfam00557 80 DVGAEYDGGYCSdITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVLEEAGLgEYFPHGLGHGIG 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1127359753 228 KLMIQAPQLqgtGTRGRGPRIHEGAILHLHVilkhGTYDVviredrwtaaaeDEKRGALFTAMVEVTA 295
Cdd:pfam00557 160 LEVHEGPYI---SRGGDDRVLEPGMVFTIEP----GIYFI------------PGWGGVRIEDTVLVTE 208
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Map |
COG0024 |
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis]; |
61-304 |
4.04e-85 |
|
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439795 [Multi-domain] Cd Length: 250 Bit Score: 256.09 E-value: 4.04e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 61 KPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHR 139
Cdd:COG0024 4 KTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLEL-DRIAEEFIRdHGAIPAFLGYYGFPKSICTSVNEVVVHGIPSDR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 140 ALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVR 219
Cdd:COG0024 83 VLKDGDIVNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNRLGDIGHAIQSYAESNGYSVVR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 220 AYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHR 299
Cdd:COG0024 163 EFVGHGIGREMHEEPQVPNYGRPGRGPRLKPGMVLAIEPMINAGTPEVKVLDDGWTVVTKDGSLSAQFEHTVAVTEDGPE 242
|
....*
gi 1127359753 300 LLSAL 304
Cdd:COG0024 243 ILTLP 247
|
|
| PRK05716 |
PRK05716 |
methionine aminopeptidase; Validated |
59-302 |
1.29e-59 |
|
methionine aminopeptidase; Validated
Pssm-ID: 235576 [Multi-domain] Cd Length: 252 Bit Score: 190.73 E-value: 1.29e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 59 SQKPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLHGIPS 137
Cdd:PRK05716 4 TIKTPEEIEKMRVAGRLAAEVLDEIEPHVKPGVTTKEL-DRIAEEYIRdQGAIPAPLGYHGFPKSICTSVNEVVCHGIPS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 138 HRALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAV 217
Cdd:PRK05716 83 DKVLKEGDIVNIDVTVIKDGYHGDTSRTFGVGEISPEDKRLCEVTKEALYLGIAAVKPGARLGDIGHAIQKYAEAEGFSV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 218 VRAYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADG 297
Cdd:PRK05716 163 VREYCGHGIGRKFHEEPQIPHYGAPGDGPVLKEGMVFTIEPMINAGKREVKTLKDGWTVVTKDGSLSAQYEHTVAVTEDG 242
|
....*
gi 1127359753 298 HRLLS 302
Cdd:PRK05716 243 PEILT 247
|
|
| MetAP1 |
cd01086 |
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
66-302 |
2.39e-58 |
|
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238519 [Multi-domain] Cd Length: 238 Bit Score: 187.32 E-value: 2.39e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 66 LEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHRALKNG 144
Cdd:cd01086 1 IEGMREAGRIVAEVLDELAKAIKPGVTTKEL-DQIAHEFIEeHGAYPAPLGYYGFPKSICTSVNEVVCHGIPDDRVLKDG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 145 DLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVRAYTGY 224
Cdd:cd01086 80 DIVNIDVGVELDGYHGDSARTFIVGEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKNGYSVVREFGGH 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1127359753 225 GMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHRLLS 302
Cdd:cd01086 160 GIGRKFHEEPQIPNYGRPGTGPKLKPGMVFTIEPMINLGTYEVVTLPDGWTVVTKDGSLSAQFEHTVLITEDGPEILT 237
|
|
| met_pdase_I |
TIGR00500 |
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. ... |
61-304 |
2.00e-47 |
|
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. This model describes type I. The role of this protein in general is to produce the mature form of cytosolic proteins by removing the N-terminal methionine. [Protein fate, Protein modification and repair]
Pssm-ID: 129591 [Multi-domain] Cd Length: 247 Bit Score: 159.44 E-value: 2.00e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 61 KPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVK-EAFRHDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHR 139
Cdd:TIGR00500 4 KSPDEIEKIRKAGRLAAEVLEELEREVKPGVSTKEL-DRIAKdFIEKHGAKPAFLGYYGFPGSVCISVNEVVIHGIPDKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 140 ALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVR 219
Cdd:TIGR00500 83 VLKDGDIVNIDVGVIYDGYHGDTAKTFLVGKISPEAEKLLECTEESLYKAIEEAKPGNRIGEIGAAIQKYAEAKGFSVVR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 220 AYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHR 299
Cdd:TIGR00500 163 EYCGHGIGRKFHEEPQIPNYGKKFTNVRLKEGMVFTIEPMVNTGTEEITTAADGWTVKTKDGSLSAQFEHTIVITDNGPE 242
|
....*
gi 1127359753 300 LLSAL 304
Cdd:TIGR00500 243 ILTER 247
|
|
| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
55-297 |
1.35e-41 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 144.59 E-value: 1.35e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 55 MEVGSqkpERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAFR-HDLLPAMLGYNAFPAMAATSVNEEVLH 133
Cdd:PRK12896 8 MEIKS---PRELEKMRKIGRIVATALKEMGKAVEPGMTTKEL-DRIAEKRLEeHGAIPSPEGYYGFPGSTCISVNEEVAH 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 134 GIPSHRALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGA 213
Cdd:PRK12896 84 GIPGPRVIKDGDLVNIDVSAYLDGYHGDTGITFAVGPVSEEAEKLCRVAEEALWAGIKQVKAGRPLNDIGRAIEDFAKKN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 214 GLAVVRAYTGYGMGKLMIQAPQLQGTGTR-GRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVE 292
Cdd:PRK12896 164 GYSVVRDLTGHGVGRSLHEEPSVILTYTDpLPNRLLRPGMTLAVEPFLNLGAKDAETLDDGWTVVTPDKSLSAQFEHTVV 243
|
....*
gi 1127359753 293 VTADG 297
Cdd:PRK12896 244 VTRDG 248
|
|
| PRK12897 |
PRK12897 |
type I methionyl aminopeptidase; |
75-304 |
3.77e-34 |
|
type I methionyl aminopeptidase;
Pssm-ID: 171806 Cd Length: 248 Bit Score: 124.76 E-value: 3.77e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 75 ILSEVMRDVGRSVVAGDTTRDVaDRLVkEAF--RHDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHRALKNGDLLKLQFG 152
Cdd:PRK12897 19 LLASCHREIAKIMKPGITTKEI-NTFV-EAYleKHGATSEQKGYNGYPYAICASVNDEMCHAFPADVPLTEGDIVTIDMV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 153 VVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVRAYTGYGMGKLMIQ 232
Cdd:PRK12897 97 VNLNGGLSDSAWTYRVGKVSDEAEKLLLVAENALYKGIDQAVIGNRVGDIGYAIESYVANEGFSVARDFTGHGIGKEIHE 176
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1127359753 233 APQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGHRLLSAL 304
Cdd:PRK12897 177 EPAIFHFGKQGQGPELQEGMVITIEPIVNVGMRYSKVDLNGWTARTMDGKLSAQYEHTIAITKDGPIILTKL 248
|
|
| PLN03158 |
PLN03158 |
methionine aminopeptidase; Provisional |
62-307 |
3.55e-31 |
|
methionine aminopeptidase; Provisional
Pssm-ID: 215607 [Multi-domain] Cd Length: 396 Bit Score: 120.33 E-value: 3.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 62 PERI--LEESRRIApilSEVMRDVGRSVVAGDTTRDVaDRLVKEA-FRHDLLPAMLGYNAFPAMAATSVNEEVLHGIPSH 138
Cdd:PLN03158 140 PEQIqrMRETCRIA---REVLDAAARAIKPGVTTDEI-DRVVHEAtIAAGGYPSPLNYHFFPKSCCTSVNEVICHGIPDA 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 139 RALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVV 218
Cdd:PLN03158 216 RKLEDGDIVNVDVTVYYKGCHGDLNETFFVGNVDEASRQLVKCTYECLEKAIAIVKPGVRYREVGEVINRHATMSGLSVV 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 219 RAYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDVVIREDRWTAAAEDEKRGALFTAMVEVTADGH 298
Cdd:PLN03158 296 KSYCGHGIGELFHCAPNIPHYARNKAVGVMKAGQVFTIEPMINAGVWRDRMWPDGWTAVTADGKRSAQFEHTLLVTETGV 375
|
....*....
gi 1127359753 299 RLLSALLDA 307
Cdd:PLN03158 376 EVLTARLPS 384
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
70-295 |
7.45e-26 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 101.93 E-value: 7.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 70 RRIAPILSEVMRDVGRSVVAGDTTRDVADRLVKEAFRHdllpAMLGYNAFPAMAATSVNEEVLHGIPSHRALKNGDLLKL 149
Cdd:pfam00557 4 RKAARIAAAALEAALAAIRPGVTERELAAELEAARLRR----GGARGPAFPPIVASGPNAAIPHYIPNDRVLKPGDLVLI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 150 QFGVVSGAAFAA-QGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGL-AVVRAYTGYGMG 227
Cdd:pfam00557 80 DVGAEYDGGYCSdITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVLEEAGLgEYFPHGLGHGIG 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1127359753 228 KLMIQAPQLqgtGTRGRGPRIHEGAILHLHVilkhGTYDVviredrwtaaaeDEKRGALFTAMVEVTA 295
Cdd:pfam00557 160 LEVHEGPYI---SRGGDDRVLEPGMVFTIEP----GIYFI------------PGWGGVRIEDTVLVTE 208
|
|
| PRK07281 |
PRK07281 |
methionyl aminopeptidase; |
61-303 |
4.64e-23 |
|
methionyl aminopeptidase;
Pssm-ID: 180918 Cd Length: 286 Bit Score: 96.07 E-value: 4.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 61 KPERILEESRRIAPILSEVMRDVGRSVVAGDTTRDVADRLVKEAFRHDLLPAMLG----YNAFPAMAATSVNEEVLHGIP 136
Cdd:PRK07281 5 KSAREIEAMDRAGDFLASIHIGLRDLIKPGVDMWEVEEYVRRRCKEENVLPLQIGvdgaMMDYPYATCCGLNDEVAHAFP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 137 SHRALKNGDLLK------------------LQFGVVS---------GAAFAAQGWTFPIGRASAADNVLLSVGPRALRKA 189
Cdd:PRK07281 85 RHYILKEGDLLKvdmvlsepldksivdvskLNFDNVEqmkkytesyRGGLADSCWAYAVGTPSDEVKNLMDVTKEAMYRG 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 190 IDAVAPGCRTGDIGAAIQAEAEGAGLAVVRAYTGYGMGKLMIQAPQLQGTGTRGRGPRIHEGAILHLHVILKHGTYDvvI 269
Cdd:PRK07281 165 IEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGTAGRGLRLREGMVLTIEPMINTGTWE--I 242
|
250 260 270
....*....|....*....|....*....|....*..
gi 1127359753 270 REDRWTAAAEDEKRGAL---FTAMVEVTADGHRLLSA 303
Cdd:PRK07281 243 DTDMKTGWAHKTLDGGLscqYEHQFVITKDGPVILTS 279
|
|
| PRK12318 |
PRK12318 |
methionyl aminopeptidase; |
62-304 |
2.83e-18 |
|
methionyl aminopeptidase;
Pssm-ID: 183434 [Multi-domain] Cd Length: 291 Bit Score: 82.94 E-value: 2.83e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 62 PERIlEESRRIAPILSEVMRDVGRSVVAGDTTRDVaDRLVKEAF-RHDLLPAMLGYNA--FPAMAATSVNEEVLHGIPSH 138
Cdd:PRK12318 46 PEQI-EKIRKACQVTARILDALCEAAKEGVTTNEL-DELSRELHkEYNAIPAPLNYGSppFPKTICTSLNEVICHGIPND 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 139 RALKNGDLLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVV 218
Cdd:PRK12318 124 IPLKNGDIMNIDVSCIVDGYYGDCSRMVMIGEVSEIKKKVCQASLECLNAAIAILKPGIPLYEIGEVIENCADKYGFSVV 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 219 RAYTGYGMGKLMIQAPQLQGTGTRGRGPrIHEGAILHLHVILKHGTYDVVIR-EDRWTAAAEDEKRGALFTAMVEVTADG 297
Cdd:PRK12318 204 DQFVGHGVGIKFHENPYVPHHRNSSKIP-LAPGMIFTIEPMINVGKKEGVIDpINHWEARTCDNQPSAQWEHTILITETG 282
|
....*..
gi 1127359753 298 HRLLSAL 304
Cdd:PRK12318 283 YEILTLL 289
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
66-298 |
3.47e-16 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 75.57 E-value: 3.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 66 LEESRRIAPILSEVMRDVGRSVVAGDTTRDVAdrlvkeAFRHDLLPAMLGYNAFPAMAATSVNEEVLHGIPSHRALKNGD 145
Cdd:cd01066 1 IARLRKAAEIAEAAMAAAAEAIRPGVTEAEVA------AAIEQALRAAGGYPAGPTIVGSGARTALPHYRPDDRRLQEGD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 146 LLKLQFGVVSGAAFAAQGWTFPIGRASAADNVLLSVGPRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAVVR-AYTGY 224
Cdd:cd01066 75 LVLVDLGGVYDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALAALRPGVTAEEVDAAAREVLEEHGLGPNFgHRTGH 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1127359753 225 GMGKLMIQAPQLQGTGTRgrgpRIHEGAILHLHVILKhgtydvviredrwtaaaEDEKRGALFTAMVEVTADGH 298
Cdd:cd01066 155 GIGLEIHEPPVLKAGDDT----VLEPGMVFAVEPGLY-----------------LPGGGGVRIEDTVLVTEDGP 207
|
|
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
66-304 |
5.48e-12 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 65.23 E-value: 5.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 66 LEESRRIAPILSEVMRDVGRSVVAGDTTRDVADRLVKEAFRHDLlpamlGYNAFPAMAATSVNEEVLHGIPSHRALKNGD 145
Cdd:COG0006 79 IELMRKAARIADAAHEAALAALRPGVTEREVAAELEAAMRRRGA-----EGPSFDTIVASGENAAIPHYTPTDRPLKPGD 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 146 LLKLQFGVVSGAAFAAQGWTFPIGRASAA-----DNVLlsvgpRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAvvRA 220
Cdd:COG0006 154 LVLIDAGAEYDGYTSDITRTVAVGEPSDEqreiyEAVL-----EAQEAAIAALKPGVTGGEVDAAARDVLAEAGYG--EY 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 221 Y---TGYGMGKLMIQAPQLQGTGTRgrgpRIHEGAILHLHVILkhgtYdvviREDRWTAAAEDekrgalftaMVEVTADG 297
Cdd:COG0006 227 FphgTGHGVGLDVHEGPQISPGNDR----PLEPGMVFTIEPGI----Y----IPGIGGVRIED---------TVLVTEDG 285
|
....*..
gi 1127359753 298 HRLLSAL 304
Cdd:COG0006 286 AEVLTRL 292
|
|
| MetAP2 |
cd01088 |
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
66-233 |
5.78e-10 |
|
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238521 [Multi-domain] Cd Length: 291 Bit Score: 59.19 E-value: 5.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 66 LEESRRIAPILSEVMRDVGRSVVAGDTTRDVADRLvkEAFRHDLLPAMlgynAFPAmaATSVNEEVLHGIPS---HRALK 142
Cdd:cd01088 1 LEKYREAGEIHRQVRKYAQSLIKPGMTLLEIAEFV--ENRIRELGAGP----AFPV--NLSINECAAHYTPNagdDTVLK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 143 NGDLLKLQFGV-VSG----AAFAaqgwtfpigrasaadnvlLSVGPR----------ALRKAIDAVAPGCRTGDIGAAIQ 207
Cdd:cd01088 73 EGDVVKLDFGAhVDGyiadSAFT------------------VDFDPKyddlleaakeALNAAIKEAGPDVRLGEIGEAIE 134
|
170 180
....*....|....*....|....*.
gi 1127359753 208 AEAEGAGLAVVRAYTGYGMGKLMIQA 233
Cdd:cd01088 135 EVIESYGFKPIRNLTGHSIERYRLHA 160
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
65-227 |
1.16e-06 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 48.27 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 65 ILEESRRIApilSEVMRDVGRSVVAGDTTRDVADRLVKEAFRHDLlpamlGYNAFPAMAATSVNEEVLHGIPSHRALKNG 144
Cdd:cd01092 3 LLRKAARIA---DKAFEELLEFIKPGMTEREVAAELEYFMRKLGA-----EGPSFDTIVASGPNSALPHGVPSDRKIEEG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1127359753 145 DLLKLQFGVVSGAAFAAQGWTFPIGRASAA-----DNVLlsvgpRALRKAIDAVAPGCRTGDIGAAIQAEAEGAGLAvvr 219
Cdd:cd01092 75 DLVLIDFGAIYDGYCSDITRTVAVGEPSDElkeiyEIVL-----EAQQAAIKAVKPGVTAKEVDKAARDVIEEAGYG--- 146
|
170
....*....|..
gi 1127359753 220 AY----TGYGMG 227
Cdd:cd01092 147 EYfihrTGHGVG 158
|
|
| |
