|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-454 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 760.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 1 MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 81 EDAGGLSYLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 161 SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSL 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 241 EMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILI 320
Cdd:PRK05748 241 EMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHGGLGLILI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 321 DYLQLIEGNGK--ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRD 398
Cdd:PRK05748 321 DYLQLIQGSGRsgENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRD 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1149360841 399 DYYEREGgddddgnepKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSPREE 454
Cdd:PRK05748 401 DYYDEET---------ENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREE 447
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-450 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 701.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 10 PPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 90 SDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNST 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 170 IENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVN 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQLVM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 250 RMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIEGN 329
Cdd:TIGR00665 241 RMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHG-LGLIVIDYLQLMSGS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 330 GK-ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEReggdd 408
Cdd:TIGR00665 320 GRsENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNP----- 394
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1149360841 409 ddgnEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:TIGR00665 395 ----DSEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-450 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 677.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 13 NIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDL 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 93 ALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNSTIEN 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 173 IDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRML 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMRLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 253 CAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIEGNGK- 331
Cdd:COG0305 241 SSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHG-LGLIVIDYLQLMSGSGRs 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 332 ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEReggddddg 411
Cdd:COG0305 320 ENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNP-------- 391
|
410 420 430
....*....|....*....|....*....|....*....
gi 1149360841 412 nEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:COG0305 392 -DSEDKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-448 |
1.53e-161 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 456.11 E-value: 1.53e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 185 GLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLR 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 265 TGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIEGNGK-ENRQQEVSDISR 343
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHG-LGLIVIDYLQLMSGGSRgENRQQEISEISR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 344 QLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYereggddddgNEPKNDNVIEVI 423
Cdd:pfam03796 160 SLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYY----------NPKEPEGKAEII 229
|
250 260
....*....|....*....|....*
gi 1149360841 424 IEKNRSGARGTVELLFIKEYNKFSS 448
Cdd:pfam03796 230 IAKQRNGPTGTVKLAFLGEYTRFEN 254
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
10-449 |
5.56e-144 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 418.26 E-value: 5.56e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 10 PPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYL 89
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 90 SDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNST 169
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIADLLEQAEQRLFDIAEQAEPQQEVTLIEGLETL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 170 IENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQN-VGTKTDRSVAIFSLEMGAESLV 248
Cdd:NF040583 161 VSELELRCQSGNGITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGaLRGKPDKVVQIYSLEMPTEQLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 249 NRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRAN--IFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLI 326
Cdd:NF040583 241 MRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTDWKdrLIIDDTSYLTPALLRARARRNARKYGKPSLIMVDYLQLM 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 327 EGNGKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYeregg 406
Cdd:NF040583 321 RCPGQENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEVY----- 395
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1149360841 407 dddDGNEPkNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSL 449
Cdd:NF040583 396 ---NPNTP-DKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-447 |
1.60e-142 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 407.67 E-value: 1.60e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 185 GLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLR 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 265 TGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGK-ENRQQEVSDISR 343
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGGLGLIVIDYLQLIRGSKRaENRQQEVAEISR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 344 QLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEREggddddgNEPKndNVIEVI 423
Cdd:cd00984 161 SLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKD-------SEDK--GIAEII 231
|
250 260
....*....|....*....|....
gi 1149360841 424 IEKNRSGARGTVELLFIKEYNKFS 447
Cdd:cd00984 232 IAKNRNGPTGTVYLAFNPEYTRFT 255
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-454 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 760.26 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 1 MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 81 EDAGGLSYLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 161 SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSL 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVAIFSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 241 EMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILI 320
Cdd:PRK05748 241 EMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHGGLGLILI 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 321 DYLQLIEGNGK--ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRD 398
Cdd:PRK05748 321 DYLQLIQGSGRsgENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLYRD 400
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 1149360841 399 DYYEREGgddddgnepKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSPREE 454
Cdd:PRK05748 401 DYYDEET---------ENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREE 447
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-450 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 701.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 10 PPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 90 SDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNST 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 170 IENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVN 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAEQLVM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 250 RMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIEGN 329
Cdd:TIGR00665 241 RMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHG-LGLIVIDYLQLMSGS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 330 GK-ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEReggdd 408
Cdd:TIGR00665 320 GRsENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNP----- 394
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1149360841 409 ddgnEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:TIGR00665 395 ----DSEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-450 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 677.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 13 NIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDL 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 93 ALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNSTIEN 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 173 IDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRML 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLVMRLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 253 CAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIEGNGK- 331
Cdd:COG0305 241 SSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHG-LGLIVIDYLQLMSGSGRs 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 332 ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEReggddddg 411
Cdd:COG0305 320 ENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNP-------- 391
|
410 420 430
....*....|....*....|....*....|....*....
gi 1149360841 412 nEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:COG0305 392 -DSEDKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
8-451 |
6.54e-166 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 474.70 E-value: 6.54e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 8 RIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLS 87
Cdd:PRK05595 6 RSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 88 YLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLN 167
Cdd:PRK05595 86 YITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDVEKVIDSAEKKIFDISEKRTTSDFEPLSNVLE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 168 STIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESL 247
Cdd:PRK05595 166 RGFEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSLEMSKEQL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 248 VNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIE 327
Cdd:PRK05595 246 AYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHG-IDMILIDYLQLMS 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 328 GN-GKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEREGG 406
Cdd:PRK05595 325 GGkGSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNKETE 404
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1149360841 407 DdddgnepknDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSP 451
Cdd:PRK05595 405 D---------KNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNLDV 440
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
7-391 |
1.51e-162 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 481.17 E-value: 1.51e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 7 DRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGL 86
Cdd:PRK07773 21 GRQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIGGA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 87 SYLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVL 166
Cdd:PRK07773 101 PYLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYAEGADVAEVVDRAQAEIYDVTDRRLSEDFVALEDLL 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 167 NSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAES 246
Cdd:PRK07773 181 QPTFDEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRLAVAIFSLEMSKEQ 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 247 LVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKgNLGLILIDYLQLI 326
Cdd:PRK07773 261 LVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRLRQEA-NLGLIVVDYLQLM 339
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1149360841 327 E-GNGKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADI 391
Cdd:PRK07773 340 TsGKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGDTLI 405
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-448 |
1.53e-161 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 456.11 E-value: 1.53e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 185 GLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLR 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 265 TGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGnLGLILIDYLQLIEGNGK-ENRQQEVSDISR 343
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHG-LGLIVIDYLQLMSGGSRgENRQQEISEISR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 344 QLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYereggddddgNEPKNDNVIEVI 423
Cdd:pfam03796 160 SLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYY----------NPKEPEGKAEII 229
|
250 260
....*....|....*....|....*
gi 1149360841 424 IEKNRSGARGTVELLFIKEYNKFSS 448
Cdd:pfam03796 230 IAKQRNGPTGTVKLAFLGEYTRFEN 254
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
6-450 |
1.59e-149 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 433.96 E-value: 1.59e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 6 QDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGG 85
Cdd:PRK08760 29 QLRVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPFDAVTLGEWFESQGKLEQVGD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 86 LSYLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE-QGEEVQTILDDAERSILEVSEK--RNRSGFLSI 162
Cdd:PRK08760 109 GAYLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQpEGRESIELLASAEKAVFKIAEAgaRGRTDFVAM 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 163 AEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEM 242
Cdd:PRK08760 189 PGALKDAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFALNIAEYAAIKSKKGVAVFSMEM 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 243 GAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKgNLGLILIDY 322
Cdd:PRK08760 269 SASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVLRSKCRRLKREH-DLGLIVIDY 347
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 323 LQLIEGNG-KENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYY 401
Cdd:PRK08760 348 LQLMSVPGnSENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRESGAIEQDADMIVFIYRDDYY 427
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1149360841 402 EREGGDDddgnepknDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:PRK08760 428 NKENSPD--------KGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNLA 468
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
8-455 |
7.66e-146 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 424.32 E-value: 7.66e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 8 RIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLS 87
Cdd:PRK07004 13 KVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGLA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 88 YLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE-QGEEVQTILDDAERSILEVSEK--RNRSGFLSIAE 164
Cdd:PRK07004 93 YLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFNpQGKEVRQLLDEAESKVFSIAEEgaRGTQGFLEIGP 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 165 VLNSTIENIDRL--AQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEM 242
Cdd:PRK07004 173 LLTQVVERIDTLyhTANPSDVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGLPVAVFSMEM 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 243 GAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDY 322
Cdd:PRK07004 253 PGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLARQCGKLGLIIIDY 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 323 LQLIEGNGK-ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYY 401
Cdd:PRK07004 333 LQLMSGSSQgENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVY 412
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 1149360841 402 EREGGDdddgnepknDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSPREEF 455
Cdd:PRK07004 413 NPDSPD---------KGTAEIIIGKQRNGPIGPVRLTFLGQYTKFDNFAGAQNF 457
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
8-452 |
2.72e-145 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 423.91 E-value: 2.72e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 8 RIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLS 87
Cdd:PRK09165 19 RELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLENDEALGELGGVQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 88 YLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTI--LDDAERSILEVSEK-RNRSGFLSIAE 164
Cdd:PRK09165 99 YLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVAPQeqIEDAEQKLYELAETgRYEGGFQSFGT 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 165 VLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNV--------------GTK 230
Cdd:PRK09165 179 AITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAFNAakayrreaqpdgskKAV 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 231 TDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQ 310
Cdd:PRK09165 259 NGGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTPALSISQLRARARRLKR 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 311 EKGnLGLILIDYLQLIEGNGK---ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQ 387
Cdd:PRK09165 339 QHG-LDLLVVDYLQLIRGSSKrssDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKRPQLSDLRESGSIEQ 417
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1149360841 388 DADIVAFLYRDDYYE--REGGDDDDGNEP------KNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSPR 452
Cdd:PRK09165 418 DADVVMFVYREEYYLkrKEPREGTPKHEEwqekmeKVHNKAEVIIAKQRHGPTGTVKLAFESEFTRFGDLADR 490
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
10-449 |
5.56e-144 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 418.26 E-value: 5.56e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 10 PPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYL 89
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 90 SDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNST 169
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIADLLEQAEQRLFDIAEQAEPQQEVTLIEGLETL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 170 IENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQN-VGTKTDRSVAIFSLEMGAESLV 248
Cdd:NF040583 161 VSELELRCQSGNGITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGaLRGKPDKVVQIYSLEMPTEQLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 249 NRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRAN--IFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLI 326
Cdd:NF040583 241 MRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTDWKdrLIIDDTSYLTPALLRARARRNARKYGKPSLIMVDYLQLM 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 327 EGNGKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYeregg 406
Cdd:NF040583 321 RCPGQENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEVY----- 395
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 1149360841 407 dddDGNEPkNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSL 449
Cdd:NF040583 396 ---NPNTP-DKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
13-439 |
5.68e-144 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 417.96 E-value: 5.68e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 13 NIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDL 92
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 93 ALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE-QGEEVQTILDDAERSILEVSEKRNRS-GFLSIAEVLNSTI 170
Cdd:TIGR03600 81 SNNTPSAANISSYARIVREKAKERKLIAACQRIITLACSpDGGTAEQKVEEAQAALLALTMSDGQEdGFVTFGEVLEDVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 171 ENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNR 250
Cdd:TIGR03600 161 RDLDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMSAEQLGER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 251 MLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNG 330
Cdd:TIGR03600 241 LLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKKGGLDLIVVDYIQLMAPAR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 331 KENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYereggdddD 410
Cdd:TIGR03600 321 GRDRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYY--------D 392
|
410 420
....*....|....*....|....*....
gi 1149360841 411 GNEPKNDnVIEVIIEKNRSGARGTVELLF 439
Cdd:TIGR03600 393 AREPPAG-IAELILAKNRHGPTGTVELLF 420
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-447 |
1.60e-142 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 407.67 E-value: 1.60e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 185 GLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLR 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 265 TGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGK-ENRQQEVSDISR 343
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGGLGLIVIDYLQLIRGSKRaENRQQEVAEISR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 344 QLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYEREggddddgNEPKndNVIEVI 423
Cdd:cd00984 161 SLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKD-------SEDK--GIAEII 231
|
250 260
....*....|....*....|....
gi 1149360841 424 IEKNRSGARGTVELLFIKEYNKFS 447
Cdd:cd00984 232 IAKNRNGPTGTVYLAFNPEYTRFT 255
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
8-450 |
6.65e-138 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 405.38 E-value: 6.65e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 8 RIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLS 87
Cdd:PRK05636 68 RQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDLERVGGAP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 88 YLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE--QGEEVQTILDDAERSILEVSEKRNRSGFLSIAEV 165
Cdd:PRK05636 148 YLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEgdEGAEIDSVIDRAQQEVFAVSQKNQSEDYAVLADI 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 166 LNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMGAE 245
Cdd:PRK05636 228 LDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNKASVIFSLEMSKS 307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 246 SLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQeKGNLGLILIDYLQL 325
Cdd:PRK05636 308 EIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRSKARRLKQ-KHDLKLIVVDYLQL 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 326 I-EGNGKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYERe 404
Cdd:PRK05636 387 MsSGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQDK- 465
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1149360841 405 ggDDDDGNEPkndnviEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:PRK05636 466 --DDERAGEA------DIILAKHRGGPIDTVQVAHQLHYSRFVDMA 503
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
6-455 |
1.01e-135 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 398.98 E-value: 1.01e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 6 QDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGG 85
Cdd:PRK06904 19 QVLIPPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKSDEVGG 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 86 LSYLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE-QGEEVQTILDDAERSILEVSEKRNRS--GFLSI 162
Cdd:PRK06904 99 FAYLAELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYSpKGQDIKDILDEAERDVFSIAEKRTTAneGPQNV 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 163 AEVLNSTIENIDRLA--QNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSL 240
Cdd:PRK06904 179 INLLENTIDKIENLAatPTNNGVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEKPVLVFSL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 241 EMGAESLVNRMLCAEGSIEASHLRTGQ-LSEEEWSNLIVAMGSLS-RANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLI 318
Cdd:PRK06904 259 EMPAEQIMMRMLASLSRVDQTKIRTGQnLDQQDWAKISSTVGMFKqKPNLYIDDSSGLTPTELRSRARRVYRENGGLSLI 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 319 LIDYLQLIEGNG-KENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYR 397
Cdd:PRK06904 339 MVDYLQLMRAPGfEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQDADLIMFIYR 418
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 1149360841 398 DDYYEReggddddgNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSPREEF 455
Cdd:PRK06904 419 DEVYNE--------TTEDNKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNLANIPQY 468
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
12-446 |
1.99e-135 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 397.84 E-value: 1.99e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 12 QNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDagglsylSD 91
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKIDE-------EI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 92 LA--LAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNST 169
Cdd:PRK08506 78 LLeiLATNPIDNIEAYVEEIKEKSIKRELLSLANTIPEQAVEEDQKSSDILDEVERELYSITNGSNSEDFKDSKEVIEST 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 170 IENIDRL-AQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVgTKTDRSVAIFSLEMGAESLV 248
Cdd:PRK08506 158 MEHIKKQkRLGNKDIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKA-LNQDKGVAFFSLEMPAEQLM 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 249 NRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEG 328
Cdd:PRK08506 237 LRMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKSQHPEIGLAVIDYLQLMSG 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 329 NGKEN-RQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYY------ 401
Cdd:PRK08506 317 SGNFKdRHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDVYkereek 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 1149360841 402 EREGGDDDDGNEPKNDNVI-------EVIIEKNRSGARGTVELLFIKEYNKF 446
Cdd:PRK08506 397 EKEKKAKKEGKEERRIHFQnksieeaEIIIGKNRNGPTGTVKLRFQKEFTRF 448
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
8-446 |
1.05e-133 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 393.60 E-value: 1.05e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 8 RIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLS 87
Cdd:PRK08006 25 KVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 88 YLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE-QGEEVQTILDDAERSILEVSEKR--NRSGFLSIAE 164
Cdd:PRK08006 105 YLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDpQGRTSEDLLDLAESRVFQIAESRanKDEGPKNIAD 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 165 VLNSTIENIDRLAQN-NEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMG 243
Cdd:PRK08006 185 ILDATVARIEQLFQQpHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLEMP 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 244 AESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSL-SRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDY 322
Cdd:PRK08006 265 GEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGILlEKRNMYIDDSSGLTPTEVRSRARRIFREHGGLSLIMIDY 344
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 323 LQLIE-GNGKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYY 401
Cdd:PRK08006 345 LQLMRvPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVY 424
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1149360841 402 EreggdddDGNEPKndNVIEVIIEKNRSGARGTVELLFIKEYNKF 446
Cdd:PRK08006 425 H-------ENSDLK--GIAEIIIGKQRNGPIGTVRLTFNGQWSRF 460
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
8-446 |
4.11e-133 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 392.04 E-value: 4.11e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 8 RIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLS 87
Cdd:PRK08840 18 KVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 88 YLSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFE-QGEEVQTILDDAERSILEVSEKR--NRSGFLSIAE 164
Cdd:PRK08840 98 YLADLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGYDpQGRTSEDLLDMAESKVFAIAEARtsENEGPQNVDS 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 165 VLNSTIENIDRLAQNNEE-ITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKTDRSVAIFSLEMG 243
Cdd:PRK08840 178 ILEKTLERIELLYKTPQDgVTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDKPVLIFSLEMP 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 244 AESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSL-SRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDY 322
Cdd:PRK08840 258 AEQLMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILmEKKNMYIDDSSGLTPTEVRSRARRIAREHGGLSMIMVDY 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 323 LQLIEGNG-KENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYY 401
Cdd:PRK08840 338 LQLMRVPAlSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVY 417
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 1149360841 402 EREGgddddgnepKNDNVIEVIIEKNRSGARGTVELLFIKEYNKF 446
Cdd:PRK08840 418 NPDS---------PLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRF 453
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
9-453 |
1.19e-119 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 357.61 E-value: 1.19e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 9 IPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSY 88
Cdd:PRK06321 15 SPPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGGPSY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 89 LSDLALAVPTAANIVYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFLSIAEVLNS 168
Cdd:PRK06321 95 LITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEKKALEEPKDVATALDEAQNLLFKISQTTNLAQYVLVADKLKG 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 169 TI------------ENIDRLAQNNEE-----ITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNVGTKT 231
Cdd:PRK06321 175 LTsskdkpfllqlqERQEAFQQSAQGdsspmISGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNIAENFCFQN 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 232 DRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLaQE 311
Cdd:PRK06321 255 RLPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVNEMQEHTLLIDDQPGLKITDLRARARRM-KE 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 312 KGNLGLILIDYLQLIEGNGK----ENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQ 387
Cdd:PRK06321 334 SYDIQFLIIDYLQLLSGSGNlrnsESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESGSIEQ 413
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1149360841 388 DADIVAFLYRDDYYereggddDDGNEPkndNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLSPRE 453
Cdd:PRK06321 414 DSDLVMFLLRREYY-------DPNDKP---GTAELIVAKNRHGSIGSVPLVFEKEFARFRNYAACE 469
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
12-446 |
5.43e-104 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 316.12 E-value: 5.43e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 12 QNIEAEQAVLGSVFLDAETIIDAMeyIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQaNLLEDAGGLSYLSD 91
Cdd:PRK06749 4 QNVEAEKTVLGSLLLDGELIKECR--LTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRVDP-NFLKGIGGMEYFIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 92 LALAVPTAANIVYYAKIVEEKSLLRTliqtATGIVTKGFE--QGEEVQTILDDAERSILEVSEKRNRSGFlsiaEVLNST 169
Cdd:PRK06749 81 LMDGVPTTSNFSYYEGLVRGAWKMYQ----AGVLGHKMGErlIAEKSEKIIGETITALCELEEKDCVCEF----DLKDAL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 170 IENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTAFALNIAQNvGTKTDRSVAIFSLEMGAESLVN 249
Cdd:PRK06749 153 VDLYEELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLH-AAKSGAAVGLFSLEMSSKQLLK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 250 RMLCAEGSIEASHLRTGQ--LSEEEWSNLIVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLG-LILIDYLQLI 326
Cdd:PRK06749 232 RMASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKiLIIVDYLQLI 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 327 EGNGKE--NRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYERe 404
Cdd:PRK06749 312 TGDPKHkgNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYDK- 390
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 1149360841 405 ggddddgnEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKF 446
Cdd:PRK06749 391 --------ETMQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRF 424
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
9-111 |
3.61e-40 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 139.29 E-value: 3.61e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 9 IPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFYRRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSY 88
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 1149360841 89 LSDLALAVPTAANIVYYAKIVEE 111
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
214-442 |
8.12e-15 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 73.37 E-value: 8.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 214 VGKTAFALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAE-GSIEASHLRTGQLSEEEwSNLIVAMGSLSRANIFIDD 292
Cdd:cd19483 9 IGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKHlGKPEPLELPRDDITEEE-EDDAFDNELGSGRFFLYDH 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 293 TPGIKISEIRAKCRKLAQeKGNLGLILIDYLQ-LIEG--NGKENRQQEVsdISRQLKKLAKELKVPVIALSQLSR---GV 366
Cdd:cd19483 88 FGSLDWDNLKEKIRYMVK-VLGCKVIVLDHLTiLVSGldSSDERKELDE--IMTELAALVKELGVTIILVSHLRRpggGK 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1149360841 367 EQRQDKRPVLSDIRESGSIEQDADIVAFLyrddyyEREGGDDDdgnePKNDNVIEVIIEKNR-SGARGTVELLFIKE 442
Cdd:cd19483 165 GHEEGGEVSESDLRGSSAIAQLSDYVIGL------ERNKQADD----PVERNTTRVRVLKNRfTGETGIAGTLYYDE 231
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
375-450 |
8.48e-13 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 70.55 E-value: 8.48e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1149360841 375 VLSDIRESGSIEQDADIVAFLYRDDYYEReggDDDDGNEPkndnviEVIIEKNRSGARGTVELLFIKEYNKFSSLS 450
Cdd:PRK07773 818 VANGIIVHNSIEQDADVVILLYRPDYYDR---DDPRGGEA------EFIVAKHRNGPTGTVTLAFQLHLSRFANLA 884
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
199-399 |
1.85e-08 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 55.68 E-value: 1.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 199 GFQPE-ELIILAARPAVGKTAFALNIAQNV-------GTKTDR-SVAIFSLEMGAESLVNRM--LCAEGSIEASHLrtgq 267
Cdd:COG3598 8 GLLPEgGVTLLAGPPGTGKSFLALQLAAAVaaggpwlGRRVPPgKVLYLAAEDDRGELRRRLkaLGADLGLPFADL---- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 268 lseEEWSNLIVAMGSLsranifiDDTPGIkiseirakcRKLAQ--EKGNLGLILIDYLQ-LIEGNgkENRQQEVSDISRQ 344
Cdd:COG3598 84 ---DGRLRLLSLAGDL-------DDTDDL---------EALERaiEEEGPDLVVIDPLArVFGGD--ENDAEEMRAFLNP 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1149360841 345 LKKLAKELKVPVIALSQLSRGveqrQDKRPVLSDIRESGSIEQDADIVAFLYRDD 399
Cdd:COG3598 143 LDRLAERTGAAVLLVHHTGKG----GAGKDSGDRARGSSALRGAARSVLVLSREK 193
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
200-380 |
1.97e-08 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 54.66 E-value: 1.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 200 FQPEELIILAARPAVGKTAFALNIAQnVGTKTDRSVAIFSLEMGAESLVNRmLCAEGSIEASHlrtGQLSEEEWSNLIVA 279
Cdd:PRK05973 61 LKPGDLVLLGARPGHGKTLLGLELAV-EAMKSGRTGVFFTLEYTEQDVRDR-LRALGADRAQF---ADLFEFDTSDAICA 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 280 mgslsraNIFIDdtpgikiseirakcRKLAQEKGnlGLILIDYLQLIEgngkENRQQ-EVSDISRQLKKLAKELKVPVIA 358
Cdd:PRK05973 136 -------DYIIA--------------RLASAPRG--TLVVIDYLQLLD----QRREKpDLSVQVRALKSFARERGLIIVF 188
|
170 180
....*....|....*....|..
gi 1149360841 359 LSQLSRGVEQRQDKRPVLSDIR 380
Cdd:PRK05973 189 ISQIDRSFDPSAKPLPDIRDVR 210
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
199-365 |
8.12e-07 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 49.30 E-value: 8.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 199 GFQPE-ELIILAARPAVGKTAFALNIAQNVGTKTD----------RSVAIFSLEMGAESLVNRMLCAEgsieashlrtGQ 267
Cdd:pfam13481 28 GLLPAgGLGLLAGAPGTGKTTLALDLAAAVATGKPwlggprvpeqGKVLYVSAEGPADELRRRLRAAG----------AD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 268 LSEEEWSNLIVAMGSLsraNIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGkENRQQEVSDISRQLKK 347
Cdd:pfam13481 98 LDLPARLLFLSLVESL---PLFFLDRGGPLLDADVDALEAALEEVEDPDLVVIDPLARALGGD-ENSNSDVGRLVKALDR 173
|
170
....*....|....*...
gi 1149360841 348 LAKELKVPVIALSQLSRG 365
Cdd:pfam13481 174 LARRTGATVLLVHHVGKD 191
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
193-390 |
7.08e-06 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 48.13 E-value: 7.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 193 LDKMTAGFQPEE-LIILAARPAVGKTAFALNIAQNVgTKTDRSVAIFSLEMGAEslvnrmLCAEgSIEASHLRTG----- 266
Cdd:PHA02542 179 LNKITKGGAERKtLNVLLAGVNVGKSLGLCSLAADY-LQQGYNVLYISMEMAEE------VIAK-RIDANLLDVSlddid 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 267 QLSEEEWSNLIVAMGSLSRANIFIDDTP--GIKISEIRAKCRKLAQEKG-NLGLILIDYLQLIE----GNGKENRQQEVS 339
Cdd:PHA02542 251 DLSKAEYKAKMEKLRSKTQGKLIIKQYPtgGAHAGHFRALLNELKLKKNfKPDVIIVDYLGICAssrlRVSSENSYTYVK 330
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 1149360841 340 DISRQLKKLAKELKVPVIALSQLSRGVEQRQDkrPVLSDIRESGSIEQDAD 390
Cdd:PHA02542 331 AIAEELRGLAVEHDVVVWTAAQTTRSGWDSSD--VDMSDTAESAGLPATAD 379
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
186-406 |
8.25e-06 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 46.83 E-value: 8.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 186 LPTGYQGLDKMTA-GFQPEELIILAARPAVGKTAFALNIAQNvGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEAsHLR 264
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFLAE-GLRRGEKGLYVSFEESPEQLLRRAESLGLDLEE-YIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 265 TGQLseeewsnlivamgslsranIFIDDTP---GIKISEIRAKCRKLAQEKGNlGLILIDYLQLIEGNGKEnrQQEVSDI 341
Cdd:COG0467 80 SGLL-------------------RIIDLSPeelGLDLEELLARLREAVEEFGA-KRVVIDSLSGLLLALPD--PERLREF 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1149360841 342 SRQLKKLAKELKVPVIALSQLsrgveqrqdkrPVLSDIRESGSIEQDADIVAFLyrddYYEREGG 406
Cdd:COG0467 138 LHRLLRYLKKRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILL----RYVELGG 187
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
292-386 |
3.13e-04 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 40.18 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 292 DTPGIKISEIRAKCRKLAQ--EKGNLGLILIDYLQLIEGNGKENRQQEVSDISRQLKKLAKELKVPVIALSQLSRGVEqr 369
Cdd:cd01120 26 DEPVIFISFLDTILEAIEDliEEKKLDIIIIDSLSSLARASQGDRSSELLEDLAKLLRAARNTGITVIATIHSDKFDI-- 103
|
90
....*....|....*..
gi 1149360841 370 qDKRPVLSDIRESGSIE 386
Cdd:cd01120 104 -DRGGSSNDERLLKSLR 119
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
186-363 |
2.69e-03 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 39.17 E-value: 2.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 186 LPTGYQGLDKMTAGFQPE-ELIILAARPAVGKTAFALNIAQNvGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHlR 264
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKgSVTLLTGGPGTGKTLFGLQFLYA-GAKNGEPGLFFTFEESPERLLRNAKSFGWDFDEME-D 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 265 TGQLSeeewsnlIVAMGSLSRANIFIDDTPGIKISEIrakcrklaqEKGNLGLILIDYLQLIEgNGKENRQQEVSdISRQ 344
Cdd:cd01124 79 EGKLI-------IVDAPPTEAGRFSLDELLSRILSII---------KSFKAKRVVIDSLSGLR-RAKEDQMRARR-IVIA 140
|
170
....*....|....*....
gi 1149360841 345 LKKLAKELKVPVIALSQLS 363
Cdd:cd01124 141 LLNELRAAGVTTIFTSEMR 159
|
|
| RepA_RSF1010_like |
cd01125 |
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family ... |
207-357 |
3.61e-03 |
|
Hexameric Replicative Helicase RepA of plasmid RSF1010 and related proteins; This family includes the homo-hexameric replicative helicase RepA encoded by plasmid RSF1010. RSF1010 is found in most Gram-negative bacteria and some Gram-positive bacteria . The RepA protein of Plasmid RSF1010 is a 5'-3' DNA helicase which can utilize ATP, dATP, GTP and dGTP (and CTP and dCTP to a lesser extent).
Pssm-ID: 410870 Cd Length: 238 Bit Score: 38.90 E-value: 3.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 207 ILAARPAVGKTAFALNIAQNVGTKTDR---------SVAIFSLEMGAESLVNRM--LCAEGSIEASHLRtgqlseeewSN 275
Cdd:cd01125 5 MLVGPPGSGKSFLALDLAVAVATGRDWlgerrvkqgRVVYLAAEDPRDGLRRRLkaIGAHLGDEDAALA---------EN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1149360841 276 LIVAMGSLsranifiddtPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENRQQEVSDISRQLKKLAKELKVP 355
Cdd:cd01125 76 LVIENLRG----------KPVSIDAEAPELERIIEELEGVRLIIIDTLARVLHGGDENDAADMGAFVAGLDRIARETGAA 145
|
..
gi 1149360841 356 VI 357
Cdd:cd01125 146 VL 147
|
|
| |
