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Conserved domains on  [gi|118404982|ref|NP_001072795|]
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uncharacterized protein LOC780256 [Xenopus tropicalis]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Myb_DNA-bind_5 pfam13873
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 327-404 3.36e-14

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. This family is greatly expanded in arthropods and higher eukaryotes.


:

Pssm-ID: 433544  Cd Length: 78  Bit Score: 68.08  E-value: 3.36e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 118404982  327 RKARFNPEELAIVAEELSSYNKLLFRAQHNLADVQRKAHKWAEILRRVNAVSITHRTIGDIKKRWHKLRRTTKKKLLQ 404
Cdd:pfam13873   1 RKKNFSEEEKEVLVELVEKRKHILEGKKSDAATWKAKNRAWKEIAARVNAIGGVHRTAEELKKKWRDLKRRTKRKLAK 78
GT1 super family cl23759
GT1, myb-like, SANT family; GT-1, a myb-like protein, is one of the GT trihelix transcription ...
 63-138 7.19e-13

GT1, myb-like, SANT family; GT-1, a myb-like protein, is one of the GT trihelix transcription factors. GT-1 binds the GT cis-element of rbcS-3A, a light-induced gene, as a dimer. Arabidopsis GT-1 is a trans-activator and acts in the stabilization of components of the transcription pre-initiation complex comprised of TFIIA-TBP-TATA. The isolated GT-1 DNA-binding domain is sufficient to bind DNA. This region closely resembles the myb domain, but with longer helices. It has been proposed that GT-1 may respond to light signals via calcium-dependent phosphorylation to create a light-modulated molecular switch. These proteins are members of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of the DNA-binding Myb domains and is found in a diverse set of proteins.


The actual alignment was detected with superfamily member pfam13873:

Pssm-ID: 474047  Cd Length: 78  Bit Score: 64.22  E-value: 7.19e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118404982   63 KKARFTPEELAIVVEELSAHNKLLFTIHQDPVKAQCKAAKWADILNRVNAHQVTFRTIDDIKKRWHDLRKTARKKL 138
Cdd:pfam13873   1 RKKNFSEEEKEVLVELVEKRKHILEGKKSDAATWKAKNRAWKEIAARVNAIGGVHRTAEELKKKWRDLKRRTKRKL 76
 
Name Accession Description Interval E-value
Myb_DNA-bind_5 pfam13873
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 327-404 3.36e-14

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. This family is greatly expanded in arthropods and higher eukaryotes.


Pssm-ID: 433544  Cd Length: 78  Bit Score: 68.08  E-value: 3.36e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 118404982  327 RKARFNPEELAIVAEELSSYNKLLFRAQHNLADVQRKAHKWAEILRRVNAVSITHRTIGDIKKRWHKLRRTTKKKLLQ 404
Cdd:pfam13873   1 RKKNFSEEEKEVLVELVEKRKHILEGKKSDAATWKAKNRAWKEIAARVNAIGGVHRTAEELKKKWRDLKRRTKRKLAK 78
Myb_DNA-bind_5 pfam13873
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 63-138 7.19e-13

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. This family is greatly expanded in arthropods and higher eukaryotes.


Pssm-ID: 433544  Cd Length: 78  Bit Score: 64.22  E-value: 7.19e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118404982   63 KKARFTPEELAIVVEELSAHNKLLFTIHQDPVKAQCKAAKWADILNRVNAHQVTFRTIDDIKKRWHDLRKTARKKL 138
Cdd:pfam13873   1 RKKNFSEEEKEVLVELVEKRKHILEGKKSDAATWKAKNRAWKEIAARVNAIGGVHRTAEELKKKWRDLKRRTKRKL 76
 
Name Accession Description Interval E-value
Myb_DNA-bind_5 pfam13873
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 327-404 3.36e-14

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. This family is greatly expanded in arthropods and higher eukaryotes.


Pssm-ID: 433544  Cd Length: 78  Bit Score: 68.08  E-value: 3.36e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 118404982  327 RKARFNPEELAIVAEELSSYNKLLFRAQHNLADVQRKAHKWAEILRRVNAVSITHRTIGDIKKRWHKLRRTTKKKLLQ 404
Cdd:pfam13873   1 RKKNFSEEEKEVLVELVEKRKHILEGKKSDAATWKAKNRAWKEIAARVNAIGGVHRTAEELKKKWRDLKRRTKRKLAK 78
Myb_DNA-bind_5 pfam13873
Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT ...
 63-138 7.19e-13

Myb/SANT-like DNA-binding domain; This presumed domain appears to be related to other Myb/SANT like DNA binding domains. This family is greatly expanded in arthropods and higher eukaryotes.


Pssm-ID: 433544  Cd Length: 78  Bit Score: 64.22  E-value: 7.19e-13
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 118404982   63 KKARFTPEELAIVVEELSAHNKLLFTIHQDPVKAQCKAAKWADILNRVNAHQVTFRTIDDIKKRWHDLRKTARKKL 138
Cdd:pfam13873   1 RKKNFSEEEKEVLVELVEKRKHILEGKKSDAATWKAKNRAWKEIAARVNAIGGVHRTAEELKKKWRDLKRRTKRKL 76
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 359-412 1.07e-03

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 38.42  E-value: 1.07e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 118404982  359 DVQRKAHKWAEILRRVNAVsithRTIGDIKKRWHKLRRTTKKKLLQMRREMQEK 412
Cdd:pfam10545  21 NRDARERAWEEIAEELGSD----VPVEDCKKRWKNLRDQYRRELRRKRTNSGEL 70
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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