|
Name |
Accession |
Description |
Interval |
E-value |
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
17-731 |
0e+00 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 768.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 17 LVIAAFLVFsiYLIRLDSVVRDKFEGKRWDIPAKVFARPLEVYTNAPISQADFTQELKLLGYKSSENYTKSGNYVSSGNE 96
Cdd:TIGR02071 8 FTAAVLLAF--YGLYLDQQIRSRFDGKVWQLPAAVYARPLNLEPGMSLSKKELLIELDATQYRQVSHVTLPGEYSVQNNS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 97 LYVHTRGFDFGDSVEPEQVLKVTFADEQVSEV-SATKPSSTGIARLEPMLIGGIYPQHNEDRVLIKLDKVPKPLIEALIA 175
Cdd:TIGR02071 86 IEVIRRPFDFPDGAEPQRRARLTFNGNQLSKIeNLDNNKEFGFFRLDPKLIAMLYSPNGEQRLFVPRDQFPELLVDTLLA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 176 TEDRNFYSHHGISIRGTARAIVSNVTGGK-RQGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEILEAYL 254
Cdd:TIGR02071 166 TEDRDFYEHDGISLYSIGRAVWVNLTAGRtVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRILELYL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 255 NEVNLGQNGNYSINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYLTQEQY 334
Cdd:TIGR02071 246 NEVYLGQSGDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEY 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 335 ETETARPLNVIAKPTLGpSRFPDFLDIVRRQLRTEYQEGDLTNQGLRIFTTLDPIAQTKIQDSFKATVNRLSRgSNRLKE 414
Cdd:TIGR02071 326 DMLSARPLGVQKKGGII-SRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPALKK-KKKLPD 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 415 LQGAVLVAHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-QSGRYNWASPVEDSSISI-QSNGQSWT 491
Cdd:TIGR02071 404 LEAAMVVTDRFTGEVRAMVGGSDpQFAGFNRALQARRQIGSLVKPAVYLTALsQPDKYRLNTWIEDQPLSIkLSNGQVWS 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 492 PKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVT-SNIPSYPSIFLGAVDMSPMEVLGIYGNFATG 570
Cdd:TIGR02071 484 PQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINkDEIPPVPSMLLGAINLTPYEVAQLYQTIASG 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 571 GFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSAYNTLPtSLKLAGKSGTTNDTRDSWF 650
Cdd:TIGR02071 564 GNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFP-SLSLAGKTGTTNDNRDSWF 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 651 AGYSGNYVSVVWLGLDDNKQTGLTGSSGALPVWTNVMSQLRQKPVNLRQPDDVQWHWIDSGSGYLAAQGCEGAMYIPLLR 730
Cdd:TIGR02071 643 AGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLSYQTPEPLLLVPPEGIDWFGVDPQGNGGCKANCPGARRLPIWT 722
|
.
gi 1196559932 731 N 731
Cdd:TIGR02071 723 G 723
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
133-705 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 677.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 133 PSSTGIARLEPMLIGGIYPqhnEDRVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVT-GGKRQGGSTL 211
Cdd:COG0744 53 PQTSTIYDRDGTLIATLGD---ENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTaGGVVQGGSTI 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 212 TQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGMPLRELNIAQQA 291
Cdd:COG0744 130 TQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG----AYGIEAAAQYYFGKSASDLTLAEAA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 292 YLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYLTQEQYETETARPLNVIAKPT-LGPSRFPDFLDIVRRQLRTEY 370
Cdd:COG0744 206 LLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNgAAAGKYPYFVDYVRRELEELL 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 371 QEGDLTNQGLRIFTTLDPIAQTKIQDSFKATVNRlsrgsNRLKELQGAVLVAHPENGELVAAVGSTQ-DFTGFNRALDAK 449
Cdd:COG0744 286 GEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPE-----GKPGGLQAALVVVDPKTGEVLAMVGGRDyGKSQFNRATQAK 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 450 RQVGSLLKPVIYLSAIQSGrYNWASPVEDSSISIqsNGQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTF 529
Cdd:COG0744 361 RQPGSTFKPFVYAAALEQG-YTPATTVDDEPVTF--PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKV 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 530 SNHLKRFGVTSNIPSYPSIFLGAVDMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVL 609
Cdd:COG0744 438 VDTARRLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLM 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 610 NYGLQQVMTSGTGRSAYntlPTSLKLAGKSGTTNDTRDSWFAGYSGNYVSVVWLGLDDNKQTG-LTGSSGALPVWTNVMS 688
Cdd:COG0744 518 TDMLQDVVTSGTGRAAR---LPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGyVTGGSLPAPIWRDFME 594
|
570
....*....|....*....
gi 1196559932 689 QLRQK--PVNLRQPDDVQW 705
Cdd:COG0744 595 AALEGlpVEDFPKPSGVVR 613
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
12-774 |
0e+00 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 563.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 12 LIFCILVIAAfLVFSIYLIRLDSVVRDKFEGKRWDIPAKVFARPLEVYTNAPISQADFTQELKLLGYKSSENYTKSGNYV 91
Cdd:PRK09506 66 LLLKLFIVFA-VLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKNEMVKLLEATQYRQVSKMTRPGEFT 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 92 SSGNELYVHTRGFDFGDSVEPEQVLKVTFADEQVSEV-SATKPSSTGIARLEPMLIGGIYPQHNEDRVLIKLDKVPKPLI 170
Cdd:PRK09506 145 VQANSIEMIRRPFDFPDSKEGQVRARLTFDGDRLATIvNLDNNRQFGFFRLDPRLITMLQSPNGEQRLFVPRSGFPDLLV 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 171 EALIATEDRNFYSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEI 249
Cdd:PRK09506 225 DTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTvQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRI 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 250 LEAYLNEVNLGQNGNYSINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYL 329
Cdd:PRK09506 305 LELYLNEVYLGQSGDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQII 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 330 TQEQYETETARPLNViaKPTLGP-SRFPDFLDIVRRQLRTEYqeGDLTN--QGLRIFTTLDPIAQTKIQDSFKATVNRLs 406
Cdd:PRK09506 385 DQELYDMLSARPLGV--QPKGGViSPQPAFMQMVRQELQAKL--GDKVKdlSGVKIFTTLDPVSQDAAEKAVEEGIPAL- 459
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 407 RGSNRLKELQGAVLVAHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-QSGRYNWASPVEDSSISI- 483
Cdd:PRK09506 460 KKQRKLSDLETAMVVVDRFSGEVRAMVGGSEpQFAGYNRAMQARRSIGSLAKPATYLTALsQPDKYRLNTWIADAPISLr 539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 484 QSNGQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTSN-IPSYPSIFLGAVDMSPMEVLG 562
Cdd:PRK09506 540 QPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDqLNPVPAMLLGALNLTPIEVAQ 619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 563 IYGNFATGGFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSAYNTLPTsLKLAGKSGTT 642
Cdd:PRK09506 620 AFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYPN-LHLAGKTGTT 698
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 643 NDTRDSWFAGYSGNYVSVVWLGLDDNKQTGLTGSSGALPVWTNVMSQLRQKPVNLRQPDDVQWHWIDSGSGYLAAQGceG 722
Cdd:PRK09506 699 NDLVDSWFAGIDGKEVTITWVGRDNNQPTKLYGASGAMTIYQRYLENQTPTPLNLTPPEDIVDMGVDYDGNFVCGSG--G 776
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 1196559932 723 AMYIPLLRNTiPRkaTACGLPHYQVEPTYNPETDGNQATPEQ-GDSIDNYIRE 774
Cdd:PRK09506 777 MRVLPVWTDD-PQ--SLCQQSEMQQQPSQPQQQPQQQPAEQKdSDGVAGWIKD 826
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
149-324 |
3.11e-81 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 257.45 E-value: 3.11e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 149 IYPQHNEDRVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLTPEKTI 227
Cdd:pfam00912 5 LAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLFLTPERTL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 228 KRKVNEAFMALLVELHYNKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWR 307
Cdd:pfam00912 85 TRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRG----AYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 1196559932 308 NPEAAKKRRDIVLHNML 324
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
17-731 |
0e+00 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 768.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 17 LVIAAFLVFsiYLIRLDSVVRDKFEGKRWDIPAKVFARPLEVYTNAPISQADFTQELKLLGYKSSENYTKSGNYVSSGNE 96
Cdd:TIGR02071 8 FTAAVLLAF--YGLYLDQQIRSRFDGKVWQLPAAVYARPLNLEPGMSLSKKELLIELDATQYRQVSHVTLPGEYSVQNNS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 97 LYVHTRGFDFGDSVEPEQVLKVTFADEQVSEV-SATKPSSTGIARLEPMLIGGIYPQHNEDRVLIKLDKVPKPLIEALIA 175
Cdd:TIGR02071 86 IEVIRRPFDFPDGAEPQRRARLTFNGNQLSKIeNLDNNKEFGFFRLDPKLIAMLYSPNGEQRLFVPRDQFPELLVDTLLA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 176 TEDRNFYSHHGISIRGTARAIVSNVTGGK-RQGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEILEAYL 254
Cdd:TIGR02071 166 TEDRDFYEHDGISLYSIGRAVWVNLTAGRtVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKDRILELYL 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 255 NEVNLGQNGNYSINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYLTQEQY 334
Cdd:TIGR02071 246 NEVYLGQSGDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQKIIDDEEY 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 335 ETETARPLNVIAKPTLGpSRFPDFLDIVRRQLRTEYQEGDLTNQGLRIFTTLDPIAQTKIQDSFKATVNRLSRgSNRLKE 414
Cdd:TIGR02071 326 DMLSARPLGVQKKGGII-SRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPALKK-KKKLPD 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 415 LQGAVLVAHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-QSGRYNWASPVEDSSISI-QSNGQSWT 491
Cdd:TIGR02071 404 LEAAMVVTDRFTGEVRAMVGGSDpQFAGFNRALQARRQIGSLVKPAVYLTALsQPDKYRLNTWIEDQPLSIkLSNGQVWS 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 492 PKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVT-SNIPSYPSIFLGAVDMSPMEVLGIYGNFATG 570
Cdd:TIGR02071 484 PQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINkDEIPPVPSMLLGAINLTPYEVAQLYQTIASG 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 571 GFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSAYNTLPtSLKLAGKSGTTNDTRDSWF 650
Cdd:TIGR02071 564 GNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFP-SLSLAGKTGTTNDNRDSWF 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 651 AGYSGNYVSVVWLGLDDNKQTGLTGSSGALPVWTNVMSQLRQKPVNLRQPDDVQWHWIDSGSGYLAAQGCEGAMYIPLLR 730
Cdd:TIGR02071 643 AGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLSYQTPEPLLLVPPEGIDWFGVDPQGNGGCKANCPGARRLPIWT 722
|
.
gi 1196559932 731 N 731
Cdd:TIGR02071 723 G 723
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
133-705 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 677.41 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 133 PSSTGIARLEPMLIGGIYPqhnEDRVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVT-GGKRQGGSTL 211
Cdd:COG0744 53 PQTSTIYDRDGTLIATLGD---ENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTaGGVVQGGSTI 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 212 TQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGMPLRELNIAQQA 291
Cdd:COG0744 130 TQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG----AYGIEAAAQYYFGKSASDLTLAEAA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 292 YLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYLTQEQYETETARPLNVIAKPT-LGPSRFPDFLDIVRRQLRTEY 370
Cdd:COG0744 206 LLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNgAAAGKYPYFVDYVRRELEELL 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 371 QEGDLTNQGLRIFTTLDPIAQTKIQDSFKATVNRlsrgsNRLKELQGAVLVAHPENGELVAAVGSTQ-DFTGFNRALDAK 449
Cdd:COG0744 286 GEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPE-----GKPGGLQAALVVVDPKTGEVLAMVGGRDyGKSQFNRATQAK 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 450 RQVGSLLKPVIYLSAIQSGrYNWASPVEDSSISIqsNGQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTF 529
Cdd:COG0744 361 RQPGSTFKPFVYAAALEQG-YTPATTVDDEPVTF--PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDKV 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 530 SNHLKRFGVTSNIPSYPSIFLGAVDMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVL 609
Cdd:COG0744 438 VDTARRLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLM 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 610 NYGLQQVMTSGTGRSAYntlPTSLKLAGKSGTTNDTRDSWFAGYSGNYVSVVWLGLDDNKQTG-LTGSSGALPVWTNVMS 688
Cdd:COG0744 518 TDMLQDVVTSGTGRAAR---LPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSPMGyVTGGSLPAPIWRDFME 594
|
570
....*....|....*....
gi 1196559932 689 QLRQK--PVNLRQPDDVQW 705
Cdd:COG0744 595 AALEGlpVEDFPKPSGVVR 613
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
145-750 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 568.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 145 LIGGIYPQHnedRVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNV-TGGKRQGGSTLTQQLVKNFYLTP 223
Cdd:COG5009 57 LIAEFGEER---RIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLrTGRRVQGGSTITQQVAKNFLLSP 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 224 EKTIKRKVNEAFMALLVELHYNKDEILEAYLNEVNLGQnGNYsinGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLY 303
Cdd:COG5009 134 ERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGH-RAY---GVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRY 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 304 NPWRNPEAAKKRRDIVLHNMLVMGYLTQEQYETETARPLNVIAKPTLGPSRFPDFLDIVRRQLRTEYQEGDLTNQGLRIF 383
Cdd:COG5009 210 NPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEDALYTGGLKVY 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 384 TTLDPIAQTKIQDSF---------------------------------------------------KATV---------- 402
Cdd:COG5009 290 TTLDPRLQEAAEKALrdgllaydrrhgyrgpeahldlaeedwdealaevpdvgdlrpavvlevddkSARVglrdgetgtl 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 403 ------------------NRLSRGSNRLK---------------------ELQGAVLVAHPENGELVAAVGSTqDFT--G 441
Cdd:COG5009 370 pleglkwarpyindnrrgPAPKSASDVLKpgdvirvrpvadggwrlrqipEVQGALVALDPHTGAVLALVGGF-DFEqsK 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 442 FNRALDAKRQVGSLLKPVIYLSAIQSGrYNWASPVEDSSISIQ--SNGQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVR 519
Cdd:COG5009 449 FNRATQAKRQPGSSFKPFVYAAALDNG-YTPATIINDAPIVFDdgGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVR 527
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 520 LGQEFGLSTFSNHLKRFGVTSNIPSYPSIFLGAVDMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQNGRLL--------- 590
Cdd:COG5009 528 LLQDVGIDYVIDYAERFGIYSKLPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIyradparac 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 591 ------------TRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSAYntlptSLK--LAGKSGTTNDTRDSWFAGYSGN 656
Cdd:COG5009 608 edcdaaewdgaePRLPDPAEQVIDPRTAYQMTSMLRGVVQRGTGRRAR-----ALGrdIAGKTGTTNDSKDAWFVGFTPD 682
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 657 YVSVVWLGLDDNKQTGL--TGSSGALPVWTNVMSQ-LRQKPVN-LRQPDDVQWHWIDSGSGYLAAQGCEGAMYIPLLRNT 732
Cdd:COG5009 683 LVAGVWVGFDDPRSLGRgeTGGRAALPIWIDFMKAaLKDKPEKpFPVPEGIVTVRIDPKTGLLASPGDPDAIFEAFKPGT 762
|
730
....*....|....*...
gi 1196559932 733 IPRKATACGLPHYQVEPT 750
Cdd:COG5009 763 EPTESASEDLGPDASEGT 780
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
12-774 |
0e+00 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 563.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 12 LIFCILVIAAfLVFSIYLIRLDSVVRDKFEGKRWDIPAKVFARPLEVYTNAPISQADFTQELKLLGYKSSENYTKSGNYV 91
Cdd:PRK09506 66 LLLKLFIVFA-VLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKNEMVKLLEATQYRQVSKMTRPGEFT 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 92 SSGNELYVHTRGFDFGDSVEPEQVLKVTFADEQVSEV-SATKPSSTGIARLEPMLIGGIYPQHNEDRVLIKLDKVPKPLI 170
Cdd:PRK09506 145 VQANSIEMIRRPFDFPDSKEGQVRARLTFDGDRLATIvNLDNNRQFGFFRLDPRLITMLQSPNGEQRLFVPRSGFPDLLV 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 171 EALIATEDRNFYSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEI 249
Cdd:PRK09506 225 DTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTvQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALIMDARYSKDRI 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 250 LEAYLNEVNLGQNGNYSINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYL 329
Cdd:PRK09506 305 LELYLNEVYLGQSGDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLVLRLLQQQQII 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 330 TQEQYETETARPLNViaKPTLGP-SRFPDFLDIVRRQLRTEYqeGDLTN--QGLRIFTTLDPIAQTKIQDSFKATVNRLs 406
Cdd:PRK09506 385 DQELYDMLSARPLGV--QPKGGViSPQPAFMQMVRQELQAKL--GDKVKdlSGVKIFTTLDPVSQDAAEKAVEEGIPAL- 459
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 407 RGSNRLKELQGAVLVAHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-QSGRYNWASPVEDSSISI- 483
Cdd:PRK09506 460 KKQRKLSDLETAMVVVDRFSGEVRAMVGGSEpQFAGYNRAMQARRSIGSLAKPATYLTALsQPDKYRLNTWIADAPISLr 539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 484 QSNGQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTSN-IPSYPSIFLGAVDMSPMEVLG 562
Cdd:PRK09506 540 QPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDqLNPVPAMLLGALNLTPIEVAQ 619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 563 IYGNFATGGFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSAYNTLPTsLKLAGKSGTT 642
Cdd:PRK09506 620 AFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKYPN-LHLAGKTGTT 698
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 643 NDTRDSWFAGYSGNYVSVVWLGLDDNKQTGLTGSSGALPVWTNVMSQLRQKPVNLRQPDDVQWHWIDSGSGYLAAQGceG 722
Cdd:PRK09506 699 NDLVDSWFAGIDGKEVTITWVGRDNNQPTKLYGASGAMTIYQRYLENQTPTPLNLTPPEDIVDMGVDYDGNFVCGSG--G 776
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|...
gi 1196559932 723 AMYIPLLRNTiPRkaTACGLPHYQVEPTYNPETDGNQATPEQ-GDSIDNYIRE 774
Cdd:PRK09506 777 MRVLPVWTDD-PQ--SLCQQSEMQQQPSQPQQQPQQQPAEQKdSDGVAGWIKD 826
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
156-693 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 546.47 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 156 DRVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVT-GGKRQGGSTLTQQLVKNFYLTPEKTIKRKVNEA 234
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITsGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 235 FMALLVELHYNKDEILEAYLNEVNLGqNGNYSINGyglASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKK 314
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFG-NGAYGIEA---AAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 315 RRDIVLHNMLVMGYLTQEQYETETARPLNVIAK-PTLGPSRFPDFLDIVRRQLRTEYQEgDLTNQGLRIFTTLDPIAQTK 393
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQtKKSEQYKAPYFVDYVIQELEEEYGE-ELYTGGLKIYTTLDLDAQKA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 394 IQDSFKATVNRLSRGSNrlKELQGAVLVAHPENGELVAAVGStQDFT--GFNRALDAKRQVGSLLKPVIYLSAIQSGrYN 471
Cdd:TIGR02074 236 AEKVLNTGLRVAGRRDG--DDLQAALVAIDPDTGAVRALVGG-RDYGksQFNRATQAKRQPGSTFKPFVYAAALEKG-LT 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 472 WASPVEDSSISIQSNGqSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTSNIPSYPSIFLG 551
Cdd:TIGR02074 312 PATIVNDEPITYNGNG-PWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDPVLSLALG 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 552 AVDMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSAYntlPT 631
Cdd:TIGR02074 391 TVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSAR---LP 467
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1196559932 632 SLKLAGKSGTTNDTRDSWFAGYSGNYVSVVWLGLDDNKQTGLTGSSG--ALPVWTNVMSQLRQK 693
Cdd:TIGR02074 468 GRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKSGTGGglAAPIWRDFMAEALKN 531
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
23-709 |
2.18e-172 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 515.55 E-value: 2.18e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 23 LVFSIYLIRLDSVVRDKFEGKRWDIPAKVFARPLEVYTNAPISQADFTQELKLLGYKSSENYTKSGNYVSSGNELYVHTR 102
Cdd:PRK14850 22 LLILCYGVYLYVKINRFINGKVWNFPTSIYSRIVNLEPGNSYSQKDVIHLLKSTMYRKVDLVTLPGEFSVKNNTIELIRR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 103 GFDFGDSVEPEQVLKVTF-ADEQVSEVSATKPSSTGIARLEPMLIGGIYPQHNEDRVLIKLDKVPKPLIEALIATEDRNF 181
Cdd:PRK14850 102 SFDFPDIREDEIHARLYFnKDKLVRIKNIDNNHDFSFLRLDPKLIAMLYSPEGKKRLFIPRNQYPEMLIKTLLAIEDKYF 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 182 YSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEILEAYLNEVNLG 260
Cdd:PRK14850 182 YEHDGIHLSSIGRAFLVNLMSGHTiQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYSKDRILELYLNEVYLG 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 261 QNGNYSINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYLTQEQYETETAR 340
Cdd:PRK14850 262 QDGNEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYKQKVITRKLYKDLCSR 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 341 PLNVIAKPTLGPSRfPDFLDIVRRQL--RTEYQEGDLTnqGLRIFTTLDPIAQTKIQDSFKATVNRLSRgSNRLKELQGA 418
Cdd:PRK14850 342 PLNVQSKGNIISSH-PAFIQLVCEEFhkKIHYPFKNFS--GTKIFTTLDYISQNAAEQAVKIGIPILKR-KKRLKDLEVA 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 419 VLVAHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-QSGRYNWASPVEDSSISIQ-SNGQSWTPKNY 495
Cdd:PRK14850 418 MVIIDRFSGEVRALIGSSKpEFNGYNRALKARRSIGSLSKPITYLTALsQPEKYHLNTWISDTPISIKlDNGQYWTPKNN 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 496 SGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTSN-IPSYPSIFLGAVDMSPMEVLGIYGNFATGGFKY 574
Cdd:PRK14850 498 NFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNyITPLPSISLGAINLTPMEVAQVFQIIGSGGYKS 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 575 PTKAIRTVVDQNGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTSGTGRSaYNTLPTSLKLAGKSGTTNDTRDSWFAGYS 654
Cdd:PRK14850 578 SLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKS-LGTIFKEFSLAGKTGTTNNLVDSWFVGID 656
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 1196559932 655 GNYVSVVWLGLDDNKQTGLTGSSGALPVWTNVMSQLRQKPVNLRQPDDVQWHWID 709
Cdd:PRK14850 657 GKQVVITWIGRDNNHTTKLYGSSGAMKIYKRYLQYQNPVPLVLKAPNNINMFYIN 711
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
157-746 |
1.77e-105 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 341.43 E-value: 1.77e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 157 RVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKnfYLTP-EKTIKRKVNEA 234
Cdd:COG4953 65 RLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIvSGGSTLTMQVAR--LLEPrPRTLSGKLRQI 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 235 FMALLVELHYNKDEILEAYLNEVNLGqnGNysINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKK 314
Cdd:COG4953 143 LRALQLERRYSKDEILELYLNLAPYG--GN--IEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 315 RRDIVLHNMLVMGYLTQEQYETETARPlnVIAKPTLGPSRFPDFLDIVRRQLRteyqegdltnQGLRIFTTLDPIAQTKI 394
Cdd:COG4953 219 ARDRVLARLAEAGVIDAEEAALALLEP--VPARRRPLPQLAPHLARRLLRQLP----------GGTRIRTTLDAGLQRRL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 395 QDSFKATVNRLSRGSnrlkELQGAVLVAHPENGELVAAVGSTqDFT-----GFNRALDAKRQVGSLLKPVIYLSAIQSGR 469
Cdd:COG4953 287 ERLVRRYVRRLKQNG----IHNAAVLVVDNRTGEVLAYVGSA-DFFdasrqGQVDMVRALRSPGSTLKPFLYGLALDQGL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 470 ynwASP---VEDSSISIqsngQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTSNIP--S 544
Cdd:COG4953 362 ---IHPetlLADVPTSF----GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLPpaE 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 545 YP--SIFLGAVDMSPMEVLGIYGNFATGGfkyptKAIRTVVDQNGRLLTRYGLnvqqtIDPSSAY-VLNyglqqvMTSGT 621
Cdd:COG4953 435 HYglSLILGGAEVTLEELVGLYAALARGG-----EARPLRLLAGEPASPGRRL-----LSPGAAWlVRD------ILSDV 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 622 GR----SAYNTLPTSLKLAGKSGTTNDTRDSWFAGYSGNYVSVVWLGLDDNKQT-GLTGSSGALPVWTNVMSQLRQKPVN 696
Cdd:COG4953 499 PRpdgaFGWRALDSPPPIAWKTGTSYGFRDAWAVGFTGRYTVGVWVGNPDGTPVpGLTGAEAAAPLLFDIFDLLPASRWP 578
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|..
gi 1196559932 697 L--RQPDDVQWHWIDSGSGYLAAQGCEGAMYIPLLRNTIPrkATACglPHYQ 746
Cdd:COG4953 579 LpfPPPAGLLRVEVCAPSGLLAGPNCPQRVTEWFIPGTSP--PTLC--PYHQ 626
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
149-324 |
3.11e-81 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 257.45 E-value: 3.11e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 149 IYPQHNEDRVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLTPEKTI 227
Cdd:pfam00912 5 LAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLFLTPERTL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 228 KRKVNEAFMALLVELHYNKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWR 307
Cdd:pfam00912 85 TRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRG----AYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 1196559932 308 NPEAAKKRRDIVLHNML 324
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
140-719 |
2.71e-74 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 258.91 E-value: 2.71e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 140 RLE-PMLI----GGIYPQHNEDRVL-IKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAI-VSNVTGGKRQGGSTLT 212
Cdd:PRK11636 43 RLQtPMQVysadGELIAQYGEKRRIpLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAAsVALFSGHASQGASTIT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 213 QQLVKNFYLTPEKTIKRKVNEAFMALLVELHYNKDEILEAYLNEVNLGqngnYSINGYGLASQFYFGMPLRELNIAQQAY 292
Cdd:PRK11636 123 QQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLG----YRAYGVGAAAQVYFGKTVDQLTLSEMAV 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 293 LVGLVQGPTLYNPWRNPEAAKKRRDIVLHNMLVMGYLTQEQYETETARPLNV-IAKPTLGPSRfPDFLDIVRRQLRTEYQ 371
Cdd:PRK11636 199 IAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIVAnYHAPEIAFSA-PYLSEMVRQEMYNRYG 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 372 EGDLTNqGLRIFTTL-------------------------------------DPIAQTKIQDSFK----------ATVNR 404
Cdd:PRK11636 278 ENAYED-GYRVYTTItrkvqqaaqqavrnnvldydmrhgyrgpanvlwkvgeSAWDNKKITDTLKalptygpllpAVVTS 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 405 ---------LSRGSN--------------RLKELQGAV----------------------------------LVA-HPEN 426
Cdd:PRK11636 357 anpqeatamLADGSSvalpmegvrwarpyRSDTQQGPTprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsaLVSiNPQN 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 427 GELVAAVGSTqDF--TGFNRALDAKRQVGSLLKPVIYLSAIQSGrYNWASPVEDSSISI--QSNGQSWTPKNYSGGEHGV 502
Cdd:PRK11636 437 GAVMALVGGF-DFnqSKFNRATQALRQVGSNIKPFLYTAAMDKG-LTLASMLNDVPISRwdAGAGSDWRPKNSPPQYAGP 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 503 VPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTS-NIPSYPSIFLGAVDMSPMEVLGIYGNFATGGFKYPTKAIRT 581
Cdd:PRK11636 515 IRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAqNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISK 594
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 582 VVDQNGRLLTR---------------YG--------------------------------------LNVQQTIDPSSAYV 608
Cdd:PRK11636 595 IENDQGGVIFEakpkvacpecdipviYGdtqksnvlenddvenvatsqeqqnssvpmpqleqanqaLVAQNGAQEYAPHV 674
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 609 LNYGLQQVMTS-------------GTGRSAYNTLPTSlKLAGKSGTTNDTRDSWFAGYSGNYVSVVWLGLDDNKQT-GLT 674
Cdd:PRK11636 675 INTPLAFLIKSalntnifgepgwmGTGWRAGRDLKRR-DIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDDHRRDlGRT 753
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196559932 675 GSSGAL---------------PVWTNVM-SQLRQKPVN-LRQPDDVQWHWIDSGSGYLAAQG 719
Cdd:PRK11636 754 TASGAIkdqisgyeggaksaqPAWDDYMkAALEGVPEQpLTPPPGIVTVNIDRSTGKLANGG 815
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
157-703 |
1.19e-45 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 175.66 E-value: 1.19e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 157 RVLIKLDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVTGGK-RQGGSTLTQQLVKnfYLTPE-KTIKRKVNEA 234
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRvISGGSTLTMQVAR--LLDPHpRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 235 FMALLVELHYNKDEILEAYLNEVNLGQngnySINGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKK 314
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGG----TLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEA 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 315 RRDIVLHNMLVMGYLTQEQyeTETARPLNVIAKPTLGPSRFPDFldiVRRQLRTEYQEgdltnqglRIFTTLDPIAQTKI 394
Cdd:PRK11240 216 ARNKVLERMAEQGVWSAEQ--VKESREEPVWLAPRQMPQLAPLF---ARMMLGKSKSD--------KIVTTLDAGLQRRL 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 395 QDSFKATVNRLSRGSNrlkelqGAVLVAHPENGELVAAVGSTqDFTGFNR-----ALDAKRQVGSLLKPVIYLSAIQSGR 469
Cdd:PRK11240 283 EDLALNWKGRLPPRSS------LAMIVVDHTDMAVRGWVGSV-DLNDDSRfghvdMVNAIRSPGSVLKPFVYGLALDDGL 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 470 YNWASPVEDssisIQSNGQSWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGVTSNIP--SYP- 546
Cdd:PRK11240 356 IHPASLLQD----VPRRTGDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPagAEPn 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 547 -SIFLGAVDMSPMEVLGIYGNFATGGfkyptKAIRTVVDQNGRLLTRyglnvqQTIDPSSAYVlnygLQQVMtSGTGRS- 624
Cdd:PRK11240 432 lSLILGGAGARLEDMVAAYSAFARHG-----KAAKLRLQPDDPLLER------PLMSPGAAWI----IRRIM-ADEAQPl 495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 625 AYNTLPTSLKLAGKSGTTNDTRDSWFAGYSGNYVSVVWLGLDDNKQT-GLTGSSGALPVWTNV----MSQLRQK----PV 695
Cdd:PRK11240 496 PDAALPRVVPLAWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVvGQFGFASAVPLLNQVnnllLSRSSQRganlPE 575
|
....*...
gi 1196559932 696 NLRqPDDV 703
Cdd:PRK11240 576 DPR-PASV 582
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
163-336 |
2.03e-35 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 134.16 E-value: 2.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 163 DKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVTGGKRQGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLVEL 242
Cdd:PRK13481 51 DNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEK 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 243 HYNKDEILEAYLNEVNLGQNgNYSINGyglASQFYFG---------MPlrELNIAQQAYLVGLVQGPTLYNPWRNPEAAK 313
Cdd:PRK13481 131 QYSKNEILSFYLNNIYFGDN-QYTLEG---AANHYFGttvnknsttMS--HITVLQSAILASKVNAPSVYNINDMSENFT 204
|
170 180
....*....|....*....|...
gi 1196559932 314 KRRDIVLHNMLVMGYLTQEQYET 336
Cdd:PRK13481 205 QRVSTNLEKMKQQNYINETQYQQ 227
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
162-332 |
1.44e-28 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 114.48 E-value: 1.44e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 162 LDKVPKPLIEALIATEDRNFYSHHGISIRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLTPEKTIKRKVNEAFMALLV 240
Cdd:TIGR02070 60 YDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVvRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWML 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 241 ELHYNKDEILEAYLNEVNLGqNGNYsinGYGLASQFYFGMPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVL 320
Cdd:TIGR02070 140 ETWWSKQRILEVYLNSVEWG-NGVF---GAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWIL 215
|
170
....*....|..
gi 1196559932 321 HNmlvMGYLTQE 332
Cdd:TIGR02070 216 KQ---MGYLGLP 224
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
378-690 |
4.68e-26 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 113.38 E-value: 4.68e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 378 QGLRIFTTLDpiaqTKIQdsfKATVNRLSRGSNRLKELQGAVLVAHPENGELVAAVGS----TQDFTG------FNRALD 447
Cdd:COG0768 217 PGKDLVLTID----SDLQ---KIAEEALKKAVEEYKAKSGAVVVMDPKTGEILAMASYpsfdPNLFVGgpdeplRNRAVQ 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 448 AKRQVGSLLKPVIYLSAIQSGRYNWASPVEDS-SISIQSngqsWTPKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGL 526
Cdd:COG0768 290 GTYEPGSTFKPFTAAAALEEGVITPDTTFDCPgYYRVGG----RTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGI 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 527 STFSNHLKRFG------------VTSNIPSYPSIFLGA---------VDMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQ 585
Cdd:COG0768 366 DKLYDYLKKFGlgqktgidlpgeASGLLPSPKRWYPGEtatmsigqgLSVTPLQLAQAYAAIANGGVLVKPHLVKEIVDP 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 586 NGRLLTRYGLNVQQTIDPSSAYVLNYGLQQVMTS--GTGRSAYNtlpTSLKLAGKSGT-----------TNDTRDSWFAG 652
Cdd:COG0768 446 DGEVVKEEPEVLRRVISPETAETVREGMEGVVNEpgGTARRAAI---PGYRVAGKTGTaqvvdignggyYKGRHIASFVG 522
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1196559932 653 Y--SGN--YVSVVWLgldDNKQTGLTGSSGALPVWTNVMSQL 690
Cdd:COG0768 523 FapADNprYAVAVVV---ENPGGGAYGGTVAAPVFREIMEAY 561
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
417-687 |
2.44e-22 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 98.26 E-value: 2.44e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 417 GAVLVAHPENGELVAAVGS-TQDFTGF-----NRALDAKRQVGSLLKPVIYLSAIQSGRYNWASPVEDSSISIQsNGQSW 490
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKpSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQ-GGKSI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 491 tpKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFGV------------TSNIPSY-----PSIFLGAV 553
Cdd:pfam00905 80 --GDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgnktgiglpgenAGYLTPYwlegaTASFGIGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 554 DMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQNGRLLTRyglnvQQTIDPSSAYVLNYGLQQVMTSGTGRSAYNTLPtsL 633
Cdd:pfam00905 158 TITPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLN-----KLPISKSTAEKVKDMLRLVVNDGTGTGTAAVPG--Y 230
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1196559932 634 KLAGKSGTT-----------NDTRDSWFAGY--SGNYVSVVWLGLDDNKqtGLTGSSGALPVWTNVM 687
Cdd:pfam00905 231 KVAGKTGTAqvagpkgggyyDGAQIGWFVGYapADNPKYAFAVLIDDPK--RYYGGKVAAPIFKDIL 295
|
|
| UB2H |
pfam14814 |
Bifunctional transglycosylase second domain; UB2H is the second domain of the ... |
59-141 |
5.90e-22 |
|
Bifunctional transglycosylase second domain; UB2H is the second domain of the transglycosylases, or penicillin-binding proteins PBP1bs)), the multi-domain membrane proteins essential for cell wall synthesis that are targeted by penicillin antibiotics. The exact function of the UB2H domain is uncertain, but it may act as the binding component of PBP1b with different binding partners, or it may participate in the regulation between DNA repair and/or synthesis and cell wall formation during the bacterial cell cycle.
Pssm-ID: 434234 [Multi-domain] Cd Length: 85 Bit Score: 90.69 E-value: 5.90e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 59 YTNAPISQADFTQELKLLGYKSSENYTKSGNYVSSGNELYVHTRGFDFGDSVEPEQVLKVTFADEQVSEVSATKP-SSTG 137
Cdd:pfam14814 2 YPGQALSAAQLEQELKLLGYRKVSNPTRPGEYSVSGNRIELYRRGFDFPDGAEPARRVRLRFAGGRVARLQDLDTgRDLA 81
|
....
gi 1196559932 138 IARL 141
Cdd:pfam14814 82 LVRL 85
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
410-687 |
3.59e-17 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 85.65 E-value: 3.59e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 410 NRLKELQGAVLVAHPENGELVAAVgSTQDF------TG-----------------FNRALDAKRQVGSLLKPVIYLSAIQ 466
Cdd:TIGR03423 242 KALGGRRGAVVVMDPRTGEILAMV-STPSFdpnlfvDGisskdykallndpdrplLNRAIQGVYPPGSTFKPVVALAALE 320
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 467 SGRYNWASPVEDSSiSIQSNGQSWtpKNYSGGEHGVVPMVQALSHSYNLSSVRLGQEFGLSTFSNHLKRFG--------- 537
Cdd:TIGR03423 321 EGVITPETRIYCPG-YFQLGGRRF--RCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGfgqktgidl 397
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 538 ---VTSNIPS------------YP------SIFLGAVDMSPMEVLGIYGNFATGGFKYPTKAIRTVVDQNGRLLTRYGLN 596
Cdd:TIGR03423 398 pgeKSGLVPSrewkrkrfgqpwYPgdtlnvSIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPE 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196559932 597 VQQTIDPSSAY--VLNYGLQQVMTS--GTGRSAYntLPTSLKLAGKSGT-----------------TNDTRD-SWFAGYs 654
Cdd:TIGR03423 478 VLRPLPISPENldVVREGMRDVVNGpgGTARRAR--LGLPYKMAGKTGTaqvvslkqgekydaeqiPERLRDhALFVAF- 554
|
330 340 350
....*....|....*....|....*....|....*....
gi 1196559932 655 GNY------VSVVWlglddnkQTGLTGSSGALPVWTNVM 687
Cdd:TIGR03423 555 APYdnpkiaVAVIV-------EHGGGGSSAAAPIARKIM 586
|
|
| |
