|
Name |
Accession |
Description |
Interval |
E-value |
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
10-736 |
0e+00 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 762.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 10 IAFIFCVLVIGAFvaFSVYLikiDNVVRAKFEGQRWDIPAKVFARPLEIYSNAAVSQDDVQEELKMLGYKNADSYAKTGS 89
Cdd:TIGR02071 4 LKLAFTAAVLLAF--YGLYL---DQQIRSRFDGKVWQLPAAVYARPLNLEPGMSLSKKELLIELDATQYRQVSHVTLPGE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 90 YVNNGNEMYVHTRGFDFGTSVEPEQVLKISFGKDTITDV-SATKPSSSGIARLEPMLIGGIYPQHNEDRVLIKLKNVPKP 168
Cdd:TIGR02071 79 YSVQNNSIEVIRRPFDFPDGAEPQRRARLTFNGNQLSKIeNLDNNKEFGFFRLDPKLIAMLYSPNGEQRLFVPRDQFPEL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 169 LIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGK-RQGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAMLIELHYDKD 247
Cdd:TIGR02071 159 LVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRtVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 248 EILEAYLNEVNLGQNGNYSINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLNNMLVMG 327
Cdd:TIGR02071 239 RILELYLNEVYLGQSGDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 328 YLTQQQYETETARPLNVIAKPTLGpARFPDFLDIVRRQLRTEYQESDLTNQGLKIFTTLDPLAQTRVQNSFKETVARLgn 407
Cdd:TIGR02071 319 IIDDEEYDMLSARPLGVQKKGGII-SRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPAL-- 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 408 ANPSRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAIES-GRYNWASQIEDSAISI- 484
Cdd:TIGR02071 396 KKKKKLPDLEAAMVVTDRFTGEVRAMVGGSDpQFAGFNRALQARRQIGSLVKPAVYLTALSQpDKYRLNTWIEDQPLSIk 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 485 QSEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVT-SNISSYPSIYLGAVDMSPMEVMS 563
Cdd:TIGR02071 476 LSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINkDEIPPVPSMLLGAINLTPYEVAQ 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 564 IYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNSGTGRSAYNTFPtSLELAGKSGTT 643
Cdd:TIGR02071 556 LYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFP-SLSLAGKTGTT 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 644 NDTRDSWFAGYSGNYAAVVWLGLDDNKITGLTGSTGALPVWINVMKQLRQKPVNLRQPNDVLWQWLDSSTGELSASGCAG 723
Cdd:TIGR02071 635 NDNRDSWFAGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLSYQTPEPLLLVPPEGIDWFGVDPQGNGGCKANCPG 714
|
730
....*....|...
gi 1196563722 724 AVHIPLLRNSMPN 736
Cdd:TIGR02071 715 ARRLPIWTGNPQA 727
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
133-713 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 675.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 133 PSSSGIARLEPMLIGGIYPqhnEDRVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVT-GGKRQGGSTL 211
Cdd:COG0744 53 PQTSTIYDRDGTLIATLGD---ENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTaGGVVQGGSTI 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 212 TQQLVKNFYLSPEKTIKRKVNEALMAMLIELHYDKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGLPLRELNIAQQA 291
Cdd:COG0744 130 TQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG----AYGIEAAAQYYFGKSASDLTLAEAA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 292 YLVGLVQGPTLYNPWRNPEAAKKRRDIVLNNMLVMGYLTQQQYETETARPLNVIAKPT-LGPARFPDFLDIVRRQLRTEY 370
Cdd:COG0744 206 LLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNgAAAGKYPYFVDYVRRELEELL 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 371 QESDLTNQGLKIFTTLDPLAQTRVQNSFKETVARlgnanpSRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDA 449
Cdd:COG0744 286 GEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPE------GKPGGLQAALVVVDPKTGEVLAMVGGRDyGKSQFNRATQA 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 450 KRQVGSLLKPVIYLSAIESGrYNWASQIEDSAISIqsEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGIST 529
Cdd:COG0744 360 KRQPGSTFKPFVYAAALEQG-YTPATTVDDEPVTF--PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDK 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 530 FINHLKKFGVTSNISSYPSIYLGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYV 609
Cdd:COG0744 437 VVDTARRLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYL 516
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 610 LNYGLQQVMNSGTGRSAYntfPTSLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDDNK-ITGLTGSTGALPVWINVM 688
Cdd:COG0744 517 MTDMLQDVVTSGTGRAAR---LPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSpMGYVTGGSLPAPIWRDFM 593
|
570 580
....*....|....*....|....*..
gi 1196563722 689 KQLRQK--PVNLRQPNDVLWQWLDSST 713
Cdd:COG0744 594 EAALEGlpVEDFPKPSGVVRIDEPSPT 620
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
2-712 |
4.93e-178 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 532.42 E-value: 4.93e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 2 KSERGIGIIAFIFCVLVIgAFVAFSVYLikiDNVVRAKFEGQRWDIPAKVFARPLEIYSNAAVSQDDVQEELKMLGYKNA 81
Cdd:PRK09506 59 GKRGWLWLLLKLFIVFAV-LIAIYGVYL---DQKIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKNEMVKLLEATQYRQV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 82 DSYAKTGSYVNNGNEMYVHTRGFDFGTSVEPEQVLKISFGKDTITDVSATKPSSS-GIARLEPMLIGGIYPQHNEDRVLI 160
Cdd:PRK09506 135 SKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDRLATIVNLDNNRQfGFFRLDPRLITMLQSPNGEQRLFV 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 161 KLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAML 239
Cdd:PRK09506 215 PRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTvQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALI 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 240 IELHYDKDEILEAYLNEVNLGQNGNYSINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIV 319
Cdd:PRK09506 295 MDARYSKDRILELYLNEVYLGQSGDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLV 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 320 LNNMLVMGYLTQQQYETETARPLNVIAKP---TLGPArfpdFLDIVRRQLRTEYQE--SDLTnqGLKIFTTLDPLAQTRV 394
Cdd:PRK09506 375 LRLLQQQQIIDQELYDMLSARPLGVQPKGgviSPQPA----FMQMVRQELQAKLGDkvKDLS--GVKIFTTLDPVSQDAA 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 395 QNSFKETVARLGNANpsRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-ESGRYN 472
Cdd:PRK09506 449 EKAVEEGIPALKKQR--KLSDLETAMVVVDRFSGEVRAMVGGSEpQFAGYNRAMQARRSIGSLAKPATYLTALsQPDKYR 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 473 WASQIEDSAISI-QSEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVTSN-ISSYPSIY 550
Cdd:PRK09506 527 LNTWIADAPISLrQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDqLNPVPAML 606
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 551 LGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNSGTGRSAYNTF 630
Cdd:PRK09506 607 LGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKY 686
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 631 PTsLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDDNKITGLTGSTGALPVWINVMKQLRQKPVNLRQPNDVLWQWLD 710
Cdd:PRK09506 687 PN-LHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRDNNQPTKLYGASGAMTIYQRYLENQTPTPLNLTPPEDIVDMGVD 765
|
..
gi 1196563722 711 SS 712
Cdd:PRK09506 766 YD 767
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
149-324 |
3.45e-80 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 254.75 E-value: 3.45e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 149 IYPQHNEDRVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLSPEKTI 227
Cdd:pfam00912 5 LAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLFLTPERTL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 228 KRKVNEALMAMLIELHYDKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWR 307
Cdd:pfam00912 85 TRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRG----AYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 1196563722 308 NPEAAKKRRDIVLNNML 324
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
10-736 |
0e+00 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 762.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 10 IAFIFCVLVIGAFvaFSVYLikiDNVVRAKFEGQRWDIPAKVFARPLEIYSNAAVSQDDVQEELKMLGYKNADSYAKTGS 89
Cdd:TIGR02071 4 LKLAFTAAVLLAF--YGLYL---DQQIRSRFDGKVWQLPAAVYARPLNLEPGMSLSKKELLIELDATQYRQVSHVTLPGE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 90 YVNNGNEMYVHTRGFDFGTSVEPEQVLKISFGKDTITDV-SATKPSSSGIARLEPMLIGGIYPQHNEDRVLIKLKNVPKP 168
Cdd:TIGR02071 79 YSVQNNSIEVIRRPFDFPDGAEPQRRARLTFNGNQLSKIeNLDNNKEFGFFRLDPKLIAMLYSPNGEQRLFVPRDQFPEL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 169 LIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGK-RQGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAMLIELHYDKD 247
Cdd:TIGR02071 159 LVDTLLATEDRDFYEHDGISLYSIGRAVWVNLTAGRtVQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALILDARYSKD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 248 EILEAYLNEVNLGQNGNYSINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLNNMLVMG 327
Cdd:TIGR02071 239 RILELYLNEVYLGQSGDDAIHGFPLASQYYFGRPLGELSLDQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 328 YLTQQQYETETARPLNVIAKPTLGpARFPDFLDIVRRQLRTEYQESDLTNQGLKIFTTLDPLAQTRVQNSFKETVARLgn 407
Cdd:TIGR02071 319 IIDDEEYDMLSARPLGVQKKGGII-SRQPAFLQLVRRELRQKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQETIPAL-- 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 408 ANPSRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAIES-GRYNWASQIEDSAISI- 484
Cdd:TIGR02071 396 KKKKKLPDLEAAMVVTDRFTGEVRAMVGGSDpQFAGFNRALQARRQIGSLVKPAVYLTALSQpDKYRLNTWIEDQPLSIk 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 485 QSEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVT-SNISSYPSIYLGAVDMSPMEVMS 563
Cdd:TIGR02071 476 LSNGQVWSPQNYDRRYSGTVMLYDALAHSLNIPTVNLGMKVGLPKVSQTWNKLGINkDEIPPVPSMLLGAINLTPYEVAQ 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 564 IYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNSGTGRSAYNTFPtSLELAGKSGTT 643
Cdd:TIGR02071 556 LYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLGADFP-SLSLAGKTGTT 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 644 NDTRDSWFAGYSGNYAAVVWLGLDDNKITGLTGSTGALPVWINVMKQLRQKPVNLRQPNDVLWQWLDSSTGELSASGCAG 723
Cdd:TIGR02071 635 NDNRDSWFAGIDGKEVTIIWLGRDDNGPTKLTGASGALQVYARYLSYQTPEPLLLVPPEGIDWFGVDPQGNGGCKANCPG 714
|
730
....*....|...
gi 1196563722 724 AVHIPLLRNSMPN 736
Cdd:TIGR02071 715 ARRLPIWTGNPQA 727
|
|
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
133-713 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 675.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 133 PSSSGIARLEPMLIGGIYPqhnEDRVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVT-GGKRQGGSTL 211
Cdd:COG0744 53 PQTSTIYDRDGTLIATLGD---ENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTaGGVVQGGSTI 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 212 TQQLVKNFYLSPEKTIKRKVNEALMAMLIELHYDKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGLPLRELNIAQQA 291
Cdd:COG0744 130 TQQLVKNLFLSNERTLSRKLKEALLALKLERKYSKDEILELYLNTVYFGRG----AYGIEAAAQYYFGKSASDLTLAEAA 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 292 YLVGLVQGPTLYNPWRNPEAAKKRRDIVLNNMLVMGYLTQQQYETETARPLNVIAKPT-LGPARFPDFLDIVRRQLRTEY 370
Cdd:COG0744 206 LLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMVEQGYITQAEADAAKAEPLTLVPPPNgAAAGKYPYFVDYVRRELEELL 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 371 QESDLTNQGLKIFTTLDPLAQTRVQNSFKETVARlgnanpSRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDA 449
Cdd:COG0744 286 GEDDLYRGGLKIYTTLDPKLQKAAEKAVKNVLPE------GKPGGLQAALVVVDPKTGEVLAMVGGRDyGKSQFNRATQA 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 450 KRQVGSLLKPVIYLSAIESGrYNWASQIEDSAISIqsEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGIST 529
Cdd:COG0744 360 KRQPGSTFKPFVYAAALEQG-YTPATTVDDEPVTF--PGGGWSPKNYDGRYRGPVTLREALANSLNTPAVRLAQEVGLDK 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 530 FINHLKKFGVTSNISSYPSIYLGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYV 609
Cdd:COG0744 437 VVDTARRLGITSPLDPNPSLALGTSEVSPLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYL 516
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 610 LNYGLQQVMNSGTGRSAYntfPTSLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDDNK-ITGLTGSTGALPVWINVM 688
Cdd:COG0744 517 MTDMLQDVVTSGTGRAAR---LPGRPVAGKTGTTNDNRDAWFVGYTPQLVTAVWVGNDDNSpMGYVTGGSLPAPIWRDFM 593
|
570 580
....*....|....*....|....*..
gi 1196563722 689 KQLRQK--PVNLRQPNDVLWQWLDSST 713
Cdd:COG0744 594 EAALEGlpVEDFPKPSGVVRIDEPSPT 620
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
145-725 |
0e+00 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 565.17 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 145 LIGGIYPQHnedRVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNV-TGGKRQGGSTLTQQLVKNFYLSP 223
Cdd:COG5009 57 LIAEFGEER---RIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLrTGRRVQGGSTITQQVAKNFLLSP 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 224 EKTIKRKVNEALMAMLIELHYDKDEILEAYLNEVNLGQnGNYsinGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLY 303
Cdd:COG5009 134 ERTLTRKIKEAILALRIEQELSKDEILELYLNKIYLGH-RAY---GVAAAAQTYFGKSLDELTLAEAAMLAGLPKAPSRY 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 304 NPWRNPEAAKKRRDIVLNNMLVMGYLTQQQYETETARPLNVIAKPTLGPARFPDFLDIVRRQLRTEYQESDLTNQGLKIF 383
Cdd:COG5009 210 NPIRNPERALERRNYVLGRMLELGYITQAEYEAAKAEPLTARYHGASAEVDAPYFAEMVRRELVERYGEDALYTGGLKVY 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 384 TTLDPLAQ------------------------TRVQNSFKETVARLGN-------------------------------- 407
Cdd:COG5009 290 TTLDPRLQeaaekalrdgllaydrrhgyrgpeAHLDLAEEDWDEALAEvpdvgdlrpavvlevddksarvglrdgetgtl 369
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 408 ------------------ANPSRLK-------------------------ELQGAVLITHPENGELVAAVGSTqDFT--G 442
Cdd:COG5009 370 pleglkwarpyindnrrgPAPKSASdvlkpgdvirvrpvadggwrlrqipEVQGALVALDPHTGAVLALVGGF-DFEqsK 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 443 FNRALDAKRQVGSLLKPVIYLSAIESGrYNWASQIEDSAISIQ--SEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVR 520
Cdd:COG5009 449 FNRATQAKRQPGSSFKPFVYAAALDNG-YTPATIINDAPIVFDdgGGGGVWRPKNYSGKFYGPTTLREALEKSRNLVTVR 527
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 521 LGQEFGISTFINHLKKFGVTSNISSYPSIYLGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSV-- 598
Cdd:COG5009 528 LLQDVGIDYVIDYAERFGIYSKLPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRIEDRNGKVIYRADPARac 607
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 599 -------------------QPTIDPSAAYVLNYGLQQVMNSGTGRSAYntfptSL--ELAGKSGTTNDTRDSWFAGYSGN 657
Cdd:COG5009 608 edcdaaewdgaeprlpdpaEQVIDPRTAYQMTSMLRGVVQRGTGRRAR-----ALgrDIAGKTGTTNDSKDAWFVGFTPD 682
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1196563722 658 YAAVVWLGLDDNKITGL--TGSTGALPVWINVMKQ-LRQKPVN-LRQPNDVLWQWLDSSTGELSASGCAGAV 725
Cdd:COG5009 683 LVAGVWVGFDDPRSLGRgeTGGRAALPIWIDFMKAaLKDKPEKpFPVPEGIVTVRIDPKTGLLASPGDPDAI 754
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
156-694 |
0e+00 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 542.62 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 156 DRVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVT-GGKRQGGSTLTQQLVKNFYLSPEKTIKRKVNEA 234
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITsGRVLEGGSTITQQLAKNLYLTNERTITRKIQEA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 235 LMAMLIELHYDKDEILEAYLNEVNLGqNGNYSINGyglASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKK 314
Cdd:TIGR02074 81 LLALKLEQKLSKDEILELYLNRIYFG-NGAYGIEA---AAQFYFGKSVNDLTLAEAAMLAGLPKAPSAYNPFKNPERAKD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 315 RRDIVLNNMLVMGYLTQQQYETETARPLNVIAK-PTLGPARFPDFLDIVRRQLRTEYQEsDLTNQGLKIFTTLDPLAQTR 393
Cdd:TIGR02074 157 RRNLVLSNMVENGYITAEEAEEAINEPIQLYLQtKKSEQYKAPYFVDYVIQELEEEYGE-ELYTGGLKIYTTLDLDAQKA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 394 VQNSFKETvarLGNANPSRLKELQGAVLITHPENGELVAAVGStQDFT--GFNRALDAKRQVGSLLKPVIYLSAIESGrY 471
Cdd:TIGR02074 236 AEKVLNTG---LRVAGRRDGDDLQAALVAIDPDTGAVRALVGG-RDYGksQFNRATQAKRQPGSTFKPFVYAAALEKG-L 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 472 NWASQIEDSAISIQSEGkAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVTSNISSYPSIYL 551
Cdd:TIGR02074 311 TPATIVNDEPITYNGNG-PWSPKNYGGGYRGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPLDPVLSLAL 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 552 GAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNSGTGRSAYntfP 631
Cdd:TIGR02074 390 GTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVVESGTGRSAR---L 466
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196563722 632 TSLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDDNKITGL--TGSTGALPVWINVMKQLRQK 694
Cdd:TIGR02074 467 PGRPVAGKTGTTQNWRDAWFVGYTPYYVTAVWVGYDDKKTLGKsgTGGGLAAPIWRDFMAEALKN 531
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
2-712 |
4.93e-178 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 532.42 E-value: 4.93e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 2 KSERGIGIIAFIFCVLVIgAFVAFSVYLikiDNVVRAKFEGQRWDIPAKVFARPLEIYSNAAVSQDDVQEELKMLGYKNA 81
Cdd:PRK09506 59 GKRGWLWLLLKLFIVFAV-LIAIYGVYL---DQKIRSRIDGKVWQLPAAVYGRMVNLEPGMSYSKNEMVKLLEATQYRQV 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 82 DSYAKTGSYVNNGNEMYVHTRGFDFGTSVEPEQVLKISFGKDTITDVSATKPSSS-GIARLEPMLIGGIYPQHNEDRVLI 160
Cdd:PRK09506 135 SKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDRLATIVNLDNNRQfGFFRLDPRLITMLQSPNGEQRLFV 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 161 KLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAML 239
Cdd:PRK09506 215 PRSGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTvQGGSTLTQQLVKNLFLSNERSLWRKANEAYMALI 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 240 IELHYDKDEILEAYLNEVNLGQNGNYSINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIV 319
Cdd:PRK09506 295 MDARYSKDRILELYLNEVYLGQSGDDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNPKLALERRNLV 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 320 LNNMLVMGYLTQQQYETETARPLNVIAKP---TLGPArfpdFLDIVRRQLRTEYQE--SDLTnqGLKIFTTLDPLAQTRV 394
Cdd:PRK09506 375 LRLLQQQQIIDQELYDMLSARPLGVQPKGgviSPQPA----FMQMVRQELQAKLGDkvKDLS--GVKIFTTLDPVSQDAA 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 395 QNSFKETVARLGNANpsRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-ESGRYN 472
Cdd:PRK09506 449 EKAVEEGIPALKKQR--KLSDLETAMVVVDRFSGEVRAMVGGSEpQFAGYNRAMQARRSIGSLAKPATYLTALsQPDKYR 526
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 473 WASQIEDSAISI-QSEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVTSN-ISSYPSIY 550
Cdd:PRK09506 527 LNTWIADAPISLrQPNGQVWSPQNDDRRFSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDqLNPVPAML 606
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 551 LGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNSGTGRSAYNTF 630
Cdd:PRK09506 607 LGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGTGRQLGAKY 686
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 631 PTsLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDDNKITGLTGSTGALPVWINVMKQLRQKPVNLRQPNDVLWQWLD 710
Cdd:PRK09506 687 PN-LHLAGKTGTTNDLVDSWFAGIDGKEVTITWVGRDNNQPTKLYGASGAMTIYQRYLENQTPTPLNLTPPEDIVDMGVD 765
|
..
gi 1196563722 711 SS 712
Cdd:PRK09506 766 YD 767
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
9-716 |
4.64e-172 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 514.78 E-value: 4.64e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 9 IIAFIFCVLVIGAFvafSVYL-IKIDNVVrakfEGQRWDIPAKVFARPLEIYSNAAVSQDDVQEELKMLGYKNADSYAKT 87
Cdd:PRK14850 14 IYVFFFVLLLILCY---GVYLyVKINRFI----NGKVWNFPTSIYSRIVNLEPGNSYSQKDVIHLLKSTMYRKVDLVTLP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 88 GSYVNNGNEMYVHTRGFDFGTSVEPEQVLKISFGKDTITDV-SATKPSSSGIARLEPMLIGGIYPQHNEDRVLIKLKNVP 166
Cdd:PRK14850 87 GEFSVKNNTIELIRRSFDFPDIREDEIHARLYFNKDKLVRIkNIDNNHDFSFLRLDPKLIAMLYSPEGKKRLFIPRNQYP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 167 KPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAMLIELHYD 245
Cdd:PRK14850 167 EMLIKTLLAIEDKYFYEHDGIHLSSIGRAFLVNLMSGHTiQGGSTLTQQLVKNLFLTNTRSLWRKINEIYMALILDRFYS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 246 KDEILEAYLNEVNLGQNGNYSINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVLNNMLV 325
Cdd:PRK14850 247 KDRILELYLNEVYLGQDGNEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNPNLTLKRRNLVLFLLYK 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 326 MGYLTQQQYETETARPLNVIAKPTLGPARfPDFLDIVRRQLRTEYQESDLTNQGLKIFTTLDPLAQTRVQNSFKETVARL 405
Cdd:PRK14850 327 QKVITRKLYKDLCSRPLNVQSKGNIISSH-PAFIQLVCEEFHKKIHYPFKNFSGTKIFTTLDYISQNAAEQAVKIGIPIL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 406 gnANPSRLKELQGAVLITHPENGELVAAVGSTQ-DFTGFNRALDAKRQVGSLLKPVIYLSAI-ESGRYNWASQIEDSAIS 483
Cdd:PRK14850 406 --KRKKRLKDLEVAMVIIDRFSGEVRALIGSSKpEFNGYNRALKARRSIGSLSKPITYLTALsQPEKYHLNTWISDTPIS 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 484 IQ-SEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVTSN-ISSYPSIYLGAVDMSPMEV 561
Cdd:PRK14850 484 IKlDNGQYWTPKNNNFSFSGKVMLIDALIHSINIPTVHLSINLGLKKLVDSWILLGISSNyITPLPSISLGAINLTPMEV 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 562 MSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNSGTGRSaYNTFPTSLELAGKSG 641
Cdd:PRK14850 564 AQVFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKS-LGTIFKEFSLAGKTG 642
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1196563722 642 TTNDTRDSWFAGYSGNYAAVVWLGLDDNKITGLTGSTGALPVWINVMKQLRQKPVNLRQPNDVLWQWLDSStGEL 716
Cdd:PRK14850 643 TTNNLVDSWFVGIDGKQVVITWIGRDNNHTTKLYGSSGAMKIYKRYLQYQNPVPLVLKAPNNINMFYINNL-GEL 716
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
157-745 |
6.21e-107 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 345.28 E-value: 6.21e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 157 RVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKnfyLS--PEKTIKRKVNE 233
Cdd:COG4953 65 RLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWQNLRSGRIvSGGSTLTMQVAR---LLepRPRTLSGKLRQ 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 234 ALMAMLIELHYDKDEILEAYLNEVNLGqnGNysINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAK 313
Cdd:COG4953 142 ILRALQLERRYSKDEILELYLNLAPYG--GN--IEGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERAR 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 314 KRRDIVLNNMLVMGYLTQQQYETETARPlnVIAKPTLGPARFPDFLDIVRRQLRteyqesdltnQGLKIFTTLDPLAQTR 393
Cdd:COG4953 218 AARDRVLARLAEAGVIDAEEAALALLEP--VPARRRPLPQLAPHLARRLLRQLP----------GGTRIRTTLDAGLQRR 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 394 VQNSFKETVARLGNANPSrlkelQGAVLITHPENGELVAAVGSTqDFT-----GFNRALDAKRQVGSLLKPVIYLSAIES 468
Cdd:COG4953 286 LERLVRRYVRRLKQNGIH-----NAAVLVVDNRTGEVLAYVGSA-DFFdasrqGQVDMVRALRSPGSTLKPFLYGLALDQ 359
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 469 GRYNWASQIEDSAISIqsegKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVTSNI--SSY 546
Cdd:COG4953 360 GLIHPETLLADVPTSF----GGYRPENFDGTFQGPVSAREALARSLNIPAVRLLEALGPARFYARLRRAGLRLLLppAEH 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 547 P--SIYLGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLeryslsvqptIDPSAAYvlnyglqQVMN--SGT 622
Cdd:COG4953 436 YglSLILGGAEVTLEELVGLYAALARGGEARPLRLLAGEPASPGRRL----------LSPGAAW-------LVRDilSDV 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 623 GR----SAYNTFPTSLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDDNK-ITGLTGSTGALPVWINVMKQLRQKPVN 697
Cdd:COG4953 499 PRpdgaFGWRALDSPPPIAWKTGTSYGFRDAWAVGFTGRYTVGVWVGNPDGTpVPGLTGAEAAAPLLFDIFDLLPASRWP 578
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1196563722 698 L--RQPNDVL-----WQwldssTGELSASGCAGAVHIPLLRNSMPnrSTACAESQ 745
Cdd:COG4953 579 LpfPPPAGLLrvevcAP-----SGLLAGPNCPQRVTEWFIPGTSP--PTLCPYHQ 626
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
149-324 |
3.45e-80 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 254.75 E-value: 3.45e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 149 IYPQHNEDRVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLSPEKTI 227
Cdd:pfam00912 5 LAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGRIvQGGSTITQQLAKNLFLTPERTL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 228 KRKVNEALMAMLIELHYDKDEILEAYLNEVNLGQNgnysINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWR 307
Cdd:pfam00912 85 TRKLKEAVLALKLERRYSKDEILEAYLNTVYFGRG----AYGIEAAARAYFGKDASDLTLAEAALLAGLPQAPSRYNPLR 160
|
170
....*....|....*..
gi 1196563722 308 NPEAAKKRRDIVLNNML 324
Cdd:pfam00912 161 NPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
140-720 |
6.41e-74 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 257.75 E-value: 6.41e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 140 RLE-PMLI----GGIYPQHNEDRVL-IKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAI-VSNVTGGKRQGGSTLT 212
Cdd:PRK11636 43 RLQtPMQVysadGELIAQYGEKRRIpLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAAsVALFSGHASQGASTIT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 213 QQLVKNFYLSPEKTIKRKVNEALMAMLIELHYDKDEILEAYLNEVNLGqngnYSINGYGLASQFYFGLPLRELNIAQQAY 292
Cdd:PRK11636 123 QQLARNFFLSPERTLMRKIKEAFLAIRIEQLLTKDEILELYLNKIYLG----YRAYGVGAAAQVYFGKTVDQLTLSEMAV 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 293 LVGLVQGPTLYNPWRNPEAAKKRRDIVLNNMLVMGYLTQQQYETETARPLNviakptlgpARF---------PDFLDIVR 363
Cdd:PRK11636 199 IAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQAQYDQARSEPIV---------ANYhapeiafsaPYLSEMVR 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 364 RQLRTEYQESDLTNqGLKIFTT----LDPLAQTRVQN------------------------------------------- 396
Cdd:PRK11636 270 QEMYNRYGENAYED-GYRVYTTitrkVQQAAQQAVRNnvldydmrhgyrgpanvlwkvgesawdnkkitdtlkalptygp 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 397 ---------SFKETVARLGN-------------ANPSRLKELQGAV---------------------------------- 420
Cdd:PRK11636 349 llpavvtsaNPQEATAMLADgssvalpmegvrwARPYRSDTQQGPTprkvtdvvqtgqqiwvrqvddawwlaqvpdvnsa 428
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 421 LIT-HPENGELVAAVGSTqDF--TGFNRALDAKRQVGSLLKPVIYLSAIESGrYNWASQIEDSAISI--QSEGKAWTPKN 495
Cdd:PRK11636 429 LVSiNPQNGAVMALVGGF-DFnqSKFNRATQALRQVGSNIKPFLYTAAMDKG-LTLASMLNDVPISRwdAGAGSDWRPKN 506
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 496 YSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGVTS-NISSYPSIYLGAVDMSPMEVMSIYGNFATGGFK 574
Cdd:PRK11636 507 SPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAqNIVHTESLALGSASFTPMQVARGYAVMANGGFL 586
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 575 YPVKSIRSVVDTNGHTL--------------------------------ERYSLSV--------QPTIDP-SAAYVLNYG 613
Cdd:PRK11636 587 VDPYFISKIENDQGGVIfeakpkvacpecdipviygdtqksnvlenddvENVATSQeqqnssvpMPQLEQaNQALVAQNG 666
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 614 LQQ----------------VMNS---------GTGRSAYNTFPTSlELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGLDD 668
Cdd:PRK11636 667 AQEyaphvintplafliksALNTnifgepgwmGTGWRAGRDLKRR-DIGGKTGTTNSSKDAWFSGYGPGVVTSVWIGFDD 745
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 669 NKIT-GLTGSTGAL---------------PVWINVMK-QLRQKPVN-LRQPNDVLWQWLDSSTGELSASG 720
Cdd:PRK11636 746 HRRDlGRTTASGAIkdqisgyeggaksaqPAWDDYMKaALEGVPEQpLTPPPGIVTVNIDRSTGKLANGG 815
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
157-703 |
3.19e-45 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 174.12 E-value: 3.19e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 157 RVLIKLKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGK-RQGGSTLTQQLVKnfYLSPE-KTIKRKVNEA 234
Cdd:PRK11240 62 RYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRvISGGSTLTMQVAR--LLDPHpRTFGGKIRQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 235 LMAMLIELHYDKDEILEAYLNEVNLGQngnySINGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKK 314
Cdd:PRK11240 140 WRALQLEWHLSKREILTLYLNRAPFGG----TLQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEA 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 315 RRDIVLNNMLVMGYLTQQQyeTETARPLNVIAKPTLGPARFPDFldiVRRQLRTEYQEsdltnqglKIFTTLDPLAQTRV 394
Cdd:PRK11240 216 ARNKVLERMAEQGVWSAEQ--VKESREEPVWLAPRQMPQLAPLF---ARMMLGKSKSD--------KIVTTLDAGLQRRL 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 395 QNSFKETVARLgnanPSRlkeLQGAVLITHPENGELVAAVGSTqDFTGFNR-----ALDAKRQVGSLLKPVIYLSAIESG 469
Cdd:PRK11240 283 EDLALNWKGRL----PPR---SSLAMIVVDHTDMAVRGWVGSV-DLNDDSRfghvdMVNAIRSPGSVLKPFVYGLALDDG 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 470 RYNWASQIEDsaisIQSEGKAWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFGV--TSNISSYP 547
Cdd:PRK11240 355 LIHPASLLQD----VPRRTGDYRPGNFDSGFHGPVSMSEALVRSLNLPAVQVLEAYGPKRFAAKLRNVGLplYLPAGAEP 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 548 --SIYLGAVDMSPMEVMSIYGNFATGGfkypvKSIRSVVDTNGHTLERYSLSvqptidPSAAYVlnygLQQVMnSGTGRS 625
Cdd:PRK11240 431 nlSLILGGAGARLEDMVAAYSAFARHG-----KAAKLRLQPDDPLLERPLMS------PGAAWI----IRRIM-ADEAQP 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 626 -AYNTFPTSLELAGKSGTTNDTRDSWFAGYSGNYAAVVWLGL-DDNKITGLTGSTGALPVW--INVMKQLRQKPVNLRQP 701
Cdd:PRK11240 495 lPDAALPRVVPLAWKTGTSYGYRDAWAIGVNARYVIGIWTGRpDGTPVVGQFGFASAVPLLnqVNNLLLSRSSQRGANLP 574
|
..
gi 1196563722 702 ND 703
Cdd:PRK11240 575 ED 576
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
164-336 |
3.95e-35 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 133.39 E-value: 3.95e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 164 NVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKRQGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAMLIELH 243
Cdd:PRK13481 52 NMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNERSFTRKVKELFVAHRVEKQ 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 244 YDKDEILEAYLNEVNLGQNgNYSINGyglASQFYFGLP-------LRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRR 316
Cdd:PRK13481 132 YSKNEILSFYLNNIYFGDN-QYTLEG---AANHYFGTTvnknsttMSHITVLQSAILASKVNAPSVYNINDMSENFTQRV 207
|
170 180
....*....|....*....|
gi 1196563722 317 DIVLNNMLVMGYLTQQQYET 336
Cdd:PRK13481 208 STNLEKMKQQNYINETQYQQ 227
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
162-330 |
8.00e-31 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 120.64 E-value: 8.00e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 162 LKNVPKPLIEALIATEDRNFYSHHGISVRGTARAIVSNVTGGKR-QGGSTLTQQLVKNFYLSPEKTIKRKVNEALMAMLI 240
Cdd:TIGR02070 60 YDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDALEKNEKSGKVvRGGSTISQQLAKNLFLWSGRSYLRKGLEAWATWML 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 241 ELHYDKDEILEAYLNEVNLGqNGNYsinGYGLASQFYFGLPLRELNIAQQAYLVGLVQGPTLYNPWRNPEAAKKRRDIVL 320
Cdd:TIGR02070 140 ETWWSKQRILEVYLNSVEWG-NGVF---GAEAAARYYFKRSASNLTRGQAARLAAVLPNPKYYDENRPGPYVRRKATWIL 215
|
170
....*....|
gi 1196563722 321 NNmlvMGYLT 330
Cdd:TIGR02070 216 KQ---MGYLG 222
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
378-691 |
5.41e-28 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 119.54 E-value: 5.41e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 378 QGLKIFTTLDPLAQTRVQNSFKETVARLGNANpsrlkelqGAVLITHPENGELVAAVGS----TQDFTG------FNRAL 447
Cdd:COG0768 217 PGKDLVLTIDSDLQKIAEEALKKAVEEYKAKS--------GAVVVMDPKTGEILAMASYpsfdPNLFVGgpdeplRNRAV 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 448 DAKRQVGSLLKPVIYLSAIESGRYNWASQIEDSAiSIQSEGkaWTPKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGI 527
Cdd:COG0768 289 QGTYEPGSTFKPFTAAAALEEGVITPDTTFDCPG-YYRVGG--RTIRDWDRGGHGTLTLTEALAKSSNVGFYKLALRLGI 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 528 STFINHLKKFG------------VTSNISSYPSIYLGA---------VDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDT 586
Cdd:COG0768 366 DKLYDYLKKFGlgqktgidlpgeASGLLPSPKRWYPGEtatmsigqgLSVTPLQLAQAYAAIANGGVLVKPHLVKEIVDP 445
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 587 NGHTLERYSLSVQPTIDPSAAYVLNYGLQQVMNS--GTGRSAYNtfpTSLELAGKSGT-----------TNDTRDSWFAG 653
Cdd:COG0768 446 DGEVVKEEPEVLRRVISPETAETVREGMEGVVNEpgGTARRAAI---PGYRVAGKTGTaqvvdignggyYKGRHIASFVG 522
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1196563722 654 Y--SGN--YAAVVWLgldDNKITGLTGSTGALPVWINVMKQL 691
Cdd:COG0768 523 FapADNprYAVAVVV---ENPGGGAYGGTVAAPVFREIMEAY 561
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
418-654 |
2.04e-22 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 98.26 E-value: 2.04e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 418 GAVLITHPENGELVAAVGS-TQDFTGF-----NRALDAKRQVGSLLKPVIYLSAIESGRYNWASQIEDSAISIQSeGKAW 491
Cdd:pfam00905 1 GSAVVLDPKTGEVLAMVGKpSYDPNGFigplrNRAVTSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQG-GKSI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 492 tpKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFG---------------------VTSNISSYpSIY 550
Cdd:pfam00905 80 --GDWNQDQVGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGygnktgiglpgenagyltpywLEGATASF-GIG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 551 LGavdMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERyslsvQPTIDPSAAYVLNYGLQQVMNSGTGRSAYNTF 630
Cdd:pfam00905 157 LT---ITPLQQAQAYAAIANGGKLVPPHLVKSIEDKVDPKVLN-----KLPISKSTAEKVKDMLRLVVNDGTGTGTAAVP 228
|
250 260 270
....*....|....*....|....*....|....*
gi 1196563722 631 PtsLELAGKSGTT-----------NDTRDSWFAGY 654
Cdd:pfam00905 229 G--YKVAGKTGTAqvagpkgggyyDGAQIGWFVGY 261
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
412-691 |
1.96e-18 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 89.89 E-value: 1.96e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 412 RLKELQGAVLITHPENGELVAAVgSTQDF------TG-----------------FNRALDAKRQVGSLLKPVIYLSAIES 468
Cdd:TIGR03423 243 ALGGRRGAVVVMDPRTGEILAMV-STPSFdpnlfvDGisskdykallndpdrplLNRAIQGVYPPGSTFKPVVALAALEE 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 469 GRYNWASQIEDSAiSIQSEGKAWtpKNYSGGEHGVVPMSQALSQSYNLSAVRLGQEFGISTFINHLKKFG---------- 538
Cdd:TIGR03423 322 GVITPETRIYCPG-YFQLGGRRF--RCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGIDKIAEYAKRFGfgqktgidlp 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 539 --VTSNISS------------YP------SIYLGAVDMSPMEVMSIYGNFATGGFKYPVKSIRSVVDTNGHTLERYSLSV 598
Cdd:TIGR03423 399 geKSGLVPSrewkrkrfgqpwYPgdtlnvSIGQGYVLVTPLQLAVATAALANGGKLYKPHLVKSIEDPDGGVVRRTEPEV 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 599 QPTIDPSAAY--VLNYGLQQVMNS--GTGRSAYNtfPTSLELAGKSGT-----------------TNDTRD-SWFAGysg 656
Cdd:TIGR03423 479 LRPLPISPENldVVREGMRDVVNGpgGTARRARL--GLPYKMAGKTGTaqvvslkqgekydaeqiPERLRDhALFVA--- 553
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 1196563722 657 nYAAVvwlglDDNKIT-------GLTGSTGALPVWINVMKQL 691
Cdd:TIGR03423 554 -FAPY-----DNPKIAvavivehGGGGSSAAAPIARKIMDAY 589
|
|
| UB2H |
pfam14814 |
Bifunctional transglycosylase second domain; UB2H is the second domain of the ... |
58-141 |
2.68e-17 |
|
Bifunctional transglycosylase second domain; UB2H is the second domain of the transglycosylases, or penicillin-binding proteins PBP1bs)), the multi-domain membrane proteins essential for cell wall synthesis that are targeted by penicillin antibiotics. The exact function of the UB2H domain is uncertain, but it may act as the binding component of PBP1b with different binding partners, or it may participate in the regulation between DNA repair and/or synthesis and cell wall formation during the bacterial cell cycle.
Pssm-ID: 434234 [Multi-domain] Cd Length: 85 Bit Score: 77.21 E-value: 2.68e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196563722 58 IYSNAAVSQDDVQEELKMLGYKNADSYAKTGSYVNNGNEMYVHTRGFDFGTSVEPEQVLKISFGKDTITDVSATKPSSS- 136
Cdd:pfam14814 1 LYPGQALSAAQLEQELKLLGYRKVSNPTRPGEYSVSGNRIELYRRGFDFPDGAEPARRVRLRFAGGRVARLQDLDTGRDl 80
|
....*
gi 1196563722 137 GIARL 141
Cdd:pfam14814 81 ALVRL 85
|
|
| |
