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Conserved domains on  [gi|125505|sp|P01044|]
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RecName: Full=Kininogen-1; AltName: Full=Kininogen I; AltName: Full=Thiol proteinase inhibitor; Contains: RecName: Full=Kininogen-1 heavy chain; Contains: RecName: Full=Bradykinin; AltName: Full=Kallidin I; Contains: RecName: Full=Lysyl-bradykinin; AltName: Full=Kallidin II; Contains: RecName: Full=Kininogen-1 light chain; Flags: Precursor

Protein Classification

CY domain-containing protein( domain architecture ID 10440427)

CY domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 3.90e-29

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 110.89  E-value: 3.90e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505     265 GCPKPIPVDSPDLEEPLSHSIAKLNAEHDGaFYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKgsNEELTKSCEINIH 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 125505     345 GQILHCDANVYVVPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-236 3.22e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 3.22e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505     143 GCVHPISTKSPDLEPVLRYAIQYFNNNTsHSHLFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKeeFSFLTPDCKSLSS 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....
gi 125505     223 GDTGECTDKAHVDV 236
Cdd:pfam00031  78 KWLGLCSAQVYKVP 91
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-115 6.06e-19

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 82.00  E-value: 6.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      24 EIDCNDQDVFKAVDAALTKYNSENkSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFqSNKTWQDCDYKDsaQAAT 103
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWL 80

                          90
                  ....*....|..
gi 125505     104 GECTATVAKRGN 115
Cdd:pfam00031  81 GLCSAQVYKVPW 92
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 3.90e-29

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 110.89  E-value: 3.90e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505     265 GCPKPIPVDSPDLEEPLSHSIAKLNAEHDGaFYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKgsNEELTKSCEINIH 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 125505     345 GQILHCDANVYVVPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-236 3.22e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 3.22e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505     143 GCVHPISTKSPDLEPVLRYAIQYFNNNTsHSHLFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKeeFSFLTPDCKSLSS 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....
gi 125505     223 GDTGECTDKAHVDV 236
Cdd:pfam00031  78 KWLGLCSAQVYKVP 91
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 262-370 5.17e-28

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 108.28  E-value: 5.17e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      262 LCAGCPKPIPVDSPDLEEPLSHSIAKLNAEHDGAFYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKGSneELTKSCEI 341
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 125505      342 NIHGQIlHCDANVYVVPWEEK-VYPTVNCQ 370
Cdd:smart00043  79 LDQGEK-FCTAKVWEKPWENKiKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 265-369 2.69e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 103.32  E-value: 2.69e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505   265 GCPKPIPVDSPDLEEPLSHSIAKLNAEHDGAfYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKGSNEELTKSCEINIH 344
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 125505   345 GQILHCDANVYVVPWEE-KVYPTVNC 369
Cdd:cd00042  80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 7.29e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 102.17  E-value: 7.29e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505   143 GCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHlFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKEEFSFLTPDCKSLSS 222
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 125505   223 GDTGECTDKAHVDVKLR-ISSFSQKC 247
Cdd:cd00042  80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 8.05e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 102.12  E-value: 8.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      141 CLGCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHLFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKEefSFLTPDCKSL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKL--SVDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 125505      221 SSGDtGECTDKA-HVDVKLRISSFSQKCD 248
Cdd:smart00043  80 DQGE-KFCTAKVwEKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-115 6.06e-19

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 82.00  E-value: 6.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      24 EIDCNDQDVFKAVDAALTKYNSENkSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFqSNKTWQDCDYKDsaQAAT 103
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWL 80

                          90
                  ....*....|..
gi 125505     104 GECTATVAKRGN 115
Cdd:pfam00031  81 GLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 3.57e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.16  E-value: 3.57e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505       23 QEIDCNDQDVFKAVDAALTKYNSENKSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFQSNKtWQDCDYKDSAQaa 102
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE-- 83

                           90       100
                   ....*....|....*....|....*
gi 125505      103 tGECTATV-AKRGNMKFSVAIQTCL 126
Cdd:smart00043  84 -KFCTAKVwEKPWENKIKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-118 8.06e-05

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 42.08  E-value: 8.06e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505    23 QEIDCNDQDVFKAVDAALTKYNSENKSGNqfvlYRITEV--ARMDN-PDTFYSLKYQIKEGDCPFQSNKTW-QDCDYKDS 98
Cdd:cd00042   4 SDIPANDPEVQELADFAVAEYNKKSNDKY----LEFFKVlsAKSQVvAGTNYYITVEAGDTNCKKSSVPLDcPDCKLLEE 79

                        90       100
                ....*....|....*....|
gi 125505    99 AQaaTGECTATVAKRGNMKF 118
Cdd:cd00042  80 GK--KKFCTAKVWEKPWENF 97
 
Name Accession Description Interval E-value
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 3.90e-29

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 110.89  E-value: 3.90e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505     265 GCPKPIPVDSPDLEEPLSHSIAKLNAEHDGaFYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKgsNEELTKSCEINIH 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKTDN-YYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 125505     345 GQILHCDANVYVVPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-236 3.22e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 108.19  E-value: 3.22e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505     143 GCVHPISTKSPDLEPVLRYAIQYFNNNTsHSHLFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKeeFSFLTPDCKSLSS 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....
gi 125505     223 GDTGECTDKAHVDV 236
Cdd:pfam00031  78 KWLGLCSAQVYKVP 91
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 262-370 5.17e-28

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 108.28  E-value: 5.17e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      262 LCAGCPKPIPVDSPDLEEPLSHSIAKLNAEHDGAFYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKGSneELTKSCEI 341
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 125505      342 NIHGQIlHCDANVYVVPWEEK-VYPTVNCQ 370
Cdd:smart00043  79 LDQGEK-FCTAKVWEKPWENKiKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 265-369 2.69e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 103.32  E-value: 2.69e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505   265 GCPKPIPVDSPDLEEPLSHSIAKLNAEHDGAfYFKIDTVKKATVQVVAGLKYSIVFIARETTCSKGSNEELTKSCEINIH 344
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 125505   345 GQILHCDANVYVVPWEE-KVYPTVNC 369
Cdd:cd00042  80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 7.29e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 102.17  E-value: 7.29e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505   143 GCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHlFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKEEFSFLTPDCKSLSS 222
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 125505   223 GDTGECTDKAHVDVKLR-ISSFSQKC 247
Cdd:cd00042  80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 141-248 8.05e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 102.12  E-value: 8.05e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      141 CLGCVHPISTKSPDLEPVLRYAIQYFNNNTSHSHLFDLKEVKRAQRQVVSGWNYEVNYSIAQTNCSKEefSFLTPDCKSL 220
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKL--SVDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 125505      221 SSGDtGECTDKA-HVDVKLRISSFSQKCD 248
Cdd:smart00043  80 DQGE-KFCTAKVwEKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 24-115 6.06e-19

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 82.00  E-value: 6.06e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      24 EIDCNDQDVFKAVDAALTKYNSENkSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFqSNKTWQDCDYKDsaQAAT 103
Cdd:pfam00031   5 PIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWL 80

                          90
                  ....*....|..
gi 125505     104 GECTATVAKRGN 115
Cdd:pfam00031  81 GLCSAQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 3.57e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.16  E-value: 3.57e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505       23 QEIDCNDQDVFKAVDAALTKYNSENKSGNQFVLYRITEVARMDNPDTFYSLKYQIKEGDCPFQSNKtWQDCDYKDSAQaa 102
Cdd:smart00043   7 SDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQGE-- 83

                           90       100
                   ....*....|....*....|....*
gi 125505      103 tGECTATV-AKRGNMKFSVAIQTCL 126
Cdd:smart00043  84 -KFCTAKVwEKPWENKIKLVEFKCT 107
Cathelicidins pfam00666
Cathelicidin; A novel protein family, showing a conserved proregion and a variable ...
 35-113 5.10e-05

Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins.


Pssm-ID: 395539  Cd Length: 101  Bit Score: 42.49  E-value: 5.10e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505      35 AVDAALTKYNSENKSGNQFVLYRITEVARMD-NPDTFYSLKYQIKEGDCPFQSNKTWQDCDYKDsaQAATGECTATVAKR 113
Cdd:pfam00666   8 AVLRAVDQFNEQSSEANLYRLLELDPPPQDDeDPDTPKPVSFRVKETVCPRTTQQPPEQCDFKE--NGLVKRCVGTVTLN 85
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-118 8.06e-05

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 42.08  E-value: 8.06e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 125505    23 QEIDCNDQDVFKAVDAALTKYNSENKSGNqfvlYRITEV--ARMDN-PDTFYSLKYQIKEGDCPFQSNKTW-QDCDYKDS 98
Cdd:cd00042   4 SDIPANDPEVQELADFAVAEYNKKSNDKY----LEFFKVlsAKSQVvAGTNYYITVEAGDTNCKKSSVPLDcPDCKLLEE 79

                        90       100
                ....*....|....*....|
gi 125505    99 AQaaTGECTATVAKRGNMKF 118
Cdd:cd00042  80 GK--KKFCTAKVWEKPWENF 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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