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Conserved domains on  [gi|12838427|dbj|BAB24199|]
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unnamed protein product [Mus musculus]

Protein Classification

solute carrier family 25 protein( domain architecture ID 10445172)

solute carrier 25 family (SLC25) protein which transfers molecules across the membranes of organelles, usually mitochondria

Gene Ontology:  GO:0016020|GO:1990542
TCDB:  2.A.29

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
118-203 1.90e-24

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.03  E-value: 1.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   118 FSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEP--KIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSC 195
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84

                  ....*...
gi 12838427   196 YRSLKRAY 203
Cdd:pfam00153  85 YETLKRLL 92
Mito_carr pfam00153
Mitochondrial carrier protein;
16-108 6.80e-22

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 88.10  E-value: 6.80e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427    16 LEVAVAGSVSGFVTRALISPLDVIKIRFQLQierlcPSDPNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYGAV 95
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|...
gi 12838427    96 QFLAFEELTELLY 108
Cdd:pfam00153  81 YFGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
212-311 6.80e-21

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 85.40  E-value: 6.80e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   212 KQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGfEHARSafgqvrSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMK 291
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQG-GSGKS------KGRGILDCFKKIYKEEGIRGLYKGLLPNLLR 73
                          90       100
                  ....*....|....*....|
gi 12838427   292 AALSTGFMFFWYELFCNLFH 311
Cdd:pfam00153  74 VAPAAAIYFGTYETLKRLLL 93
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
118-203 1.90e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.03  E-value: 1.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   118 FSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEP--KIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSC 195
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84

                  ....*...
gi 12838427   196 YRSLKRAY 203
Cdd:pfam00153  85 YETLKRLL 92
Mito_carr pfam00153
Mitochondrial carrier protein;
16-108 6.80e-22

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 88.10  E-value: 6.80e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427    16 LEVAVAGSVSGFVTRALISPLDVIKIRFQLQierlcPSDPNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYGAV 95
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|...
gi 12838427    96 QFLAFEELTELLY 108
Cdd:pfam00153  81 YFGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
212-311 6.80e-21

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 85.40  E-value: 6.80e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   212 KQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGfEHARSafgqvrSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMK 291
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQG-GSGKS------KGRGILDCFKKIYKEEGIRGLYKGLLPNLLR 73
                          90       100
                  ....*....|....*....|
gi 12838427   292 AALSTGFMFFWYELFCNLFH 311
Cdd:pfam00153  74 VAPAAAIYFGTYETLKRLLL 93
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
20-284 7.37e-20

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 87.90  E-value: 7.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   20 VAGSVSGFVTRALISPLDVIKIRFQLQierlcPSDPNAK------YHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYG 93
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTQ-----DSIPEIKsgkvprYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   94 AVQFlAFEELTELL---YQANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTRLAA---QGEPKIYNNLREAIRTMYK 167
Cdd:PTZ00169  87 AFNF-AFKDYFKNMfpkYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASdigKGGDREFTGLFDCLMKISK 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  168 TEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRA-----------YDWLIppdgKQTGNLKnllcgcgSGVISktftYP 236
Cdd:PTZ00169 166 QTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALlfgndkntnilYKWAV----AQTVTIL-------AGLIS----YP 230
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 12838427  237 LDLIKKRLQVGGFEHARSAFgqvrSYRGLLDLTQQVLQEEGTRGFFKG 284
Cdd:PTZ00169 231 FDTVRRRMMMMSGRKAKSEI----QYTGTLDCWKKILKNEGLGGFFKG 274
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
118-203 1.90e-24

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 95.03  E-value: 1.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   118 FSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEP--KIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSC 195
Cdd:pfam00153   5 FLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSgkSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIYFGT 84

                  ....*...
gi 12838427   196 YRSLKRAY 203
Cdd:pfam00153  85 YETLKRLL 92
Mito_carr pfam00153
Mitochondrial carrier protein;
16-108 6.80e-22

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 88.10  E-value: 6.80e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427    16 LEVAVAGSVSGFVTRALISPLDVIKIRFQLQierlcPSDPNAKYHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYGAV 95
Cdd:pfam00153   6 LASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-----GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|...
gi 12838427    96 QFLAFEELTELLY 108
Cdd:pfam00153  81 YFGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
212-311 6.80e-21

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 85.40  E-value: 6.80e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   212 KQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGfEHARSafgqvrSYRGLLDLTQQVLQEEGTRGFFKGLSPSLMK 291
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQG-GSGKS------KGRGILDCFKKIYKEEGIRGLYKGLLPNLLR 73
                          90       100
                  ....*....|....*....|
gi 12838427   292 AALSTGFMFFWYELFCNLFH 311
Cdd:pfam00153  74 VAPAAAIYFGTYETLKRLLL 93
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
20-284 7.37e-20

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 87.90  E-value: 7.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   20 VAGSVSGFVTRALISPLDVIKIRFQLQierlcPSDPNAK------YHGIFQAAKQILQEEGPRAFWKGHVPAQILSIGYG 93
Cdd:PTZ00169  12 LMGGISAAISKTAVAPIERVKMLIQTQ-----DSIPEIKsgkvprYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   94 AVQFlAFEELTELL---YQANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTRLAA---QGEPKIYNNLREAIRTMYK 167
Cdd:PTZ00169  87 AFNF-AFKDYFKNMfpkYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASdigKGGDREFTGLFDCLMKISK 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  168 TEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRA-----------YDWLIppdgKQTGNLKnllcgcgSGVISktftYP 236
Cdd:PTZ00169 166 QTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALlfgndkntnilYKWAV----AQTVTIL-------AGLIS----YP 230
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 12838427  237 LDLIKKRLQVGGFEHARSAFgqvrSYRGLLDLTQQVLQEEGTRGFFKG 284
Cdd:PTZ00169 231 FDTVRRRMMMMSGRKAKSEI----QYTGTLDCWKKILKNEGLGGFFKG 274
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
20-284 1.25e-08

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 54.93  E-value: 1.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   20 VAGSVSGFVTRALISPLDVIKIRFQLQiERLCPSDPNAKYHGIFQAAKqilqeegprafwkGHVPAQILsigygavqFLA 99
Cdd:PTZ00168   8 VTGALSGVIVDAVLYPIDSIKTNIQAK-KSFSFSDIKKLYSGILPTLV-------------GTVPASAF--------FYC 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  100 FEELTELLYQANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYNnlreAIRTMYKTEGPFVFY-KGL 178
Cdd:PTZ00168  66 FYELSKKLLTEYRENISKTNLYLISTSIAEITACIVRLPFEIVKQNMQVSGNISVLK----TIYEITQREGLPSFLgKSY 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  179 TPTVIAIFPYAGLQFSCYRSLKRAYDWLIPPDGKQTGNLKNLLCGCGSGVISKTFTYPLDLIKKRLQVGGfeharsafgq 258
Cdd:PTZ00168 142 FVMIVREIPFDCIQYFLWETLKEKAKKDFGKFSKKYPSITSAICGGLAGGIAGFLTTPVDVIKSRQIIYG---------- 211
                        250       260
                 ....*....|....*....|....*.
gi 12838427  259 vRSYRGlldlTQQVLQEEGTRGFFKG 284
Cdd:PTZ00168 212 -KSYIE----TVTEIAEEGYLTFYKG 232
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
118-289 3.85e-08

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 53.62  E-value: 3.85e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  118 FSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGE-PKI-------YNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYA 189
Cdd:PTZ00169   7 FATDFLMGGISAAISKTAVAPIERVKMLIQTQDSiPEIksgkvprYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPTQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  190 GLQFSCYRSLKRaydwLIPPDGKQTGNLK----NLLCGCGSGVISKTFTYPLDLIKKRL--QVGGfeharsafGQVRSYR 263
Cdd:PTZ00169  87 AFNFAFKDYFKN----MFPKYNQKTDFWKffgvNILSGGLAGASSLLIVYPLDFARTRLasDIGK--------GGDREFT 154
                        170       180
                 ....*....|....*....|....*.
gi 12838427  264 GLLDLTQQVLQEEGTRGFFKGLSPSL 289
Cdd:PTZ00169 155 GLFDCLMKISKQTGFLSLYQGFGVSV 180
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
38-193 3.26e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 38.37  E-value: 3.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427   38 VIKIRFQLQIERLCPSDPNAKYHGIFQaakqILQEEGPRAFW-KGHVPAQILSIGYGAVQFLAFEELTELLYQ--ANLYQ 114
Cdd:PTZ00168 100 IVRLPFEIVKQNMQVSGNISVLKTIYE----ITQREGLPSFLgKSYFVMIVREIPFDCIQYFLWETLKEKAKKdfGKFSK 175
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 12838427  115 THQFSAHFVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIynnlrEAIRTMYKtEGPFVFYKGLTPTVIAIFpYAGLQF 193
Cdd:PTZ00168 176 KYPSITSAICGGLAGGIAGFLTTPVDVIKSRQIIYGKSYI-----ETVTEIAE-EGYLTFYKGCCFRSSYLF-FGGLIF 247
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
121-266 7.95e-03

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 37.21  E-value: 7.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 12838427  121 HFVCGGLSAGTATLTVHPVDVLRTRLAAQGEPKIYNnlreaIRTMyktegpfvfYKGLTPTVIAIFPYAGLqFSCYRSLK 200
Cdd:PTZ00168   6 NLVTGALSGVIVDAVLYPIDSIKTNIQAKKSFSFSD-----IKKL---------YSGILPTLVGTVPASAF-FYCFYELS 70
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 12838427  201 RAydwlIPPDGKQTGNLKNLLCGCGS--GVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLL 266
Cdd:PTZ00168  71 KK----LLTEYRENISKTNLYLISTSiaEITACIVRLPFEIVKQNMQVSGNISVLKTIYEITQREGLP 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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