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Conserved domains on  [gi|1326291275|gb|PME96190|]
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Ter macrodomain-binding protein MatP [Vibrio cyclitrophicus]

Protein Classification

macrodomain Ter protein( domain architecture ID 10012251)

macrodomain Ter protein is required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle, and prevents early segregation of duplicated Ter macrodomains during cell division

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05097 PRK05097
macrodomain Ter protein MatP;
1-150 7.91e-92

macrodomain Ter protein MatP;


:

Pssm-ID: 235344 [Multi-domain]  Cd Length: 150  Bit Score: 262.97  E-value: 7.91e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   1 MKYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKR 80
Cdd:PRK05097    1 MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDELLKLENEPVKVLEWIDKHMNPELVNRMKQTIRARRKR 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275  81 HFNAEQVHTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTSLKEDLSKLLSDD 150
Cdd:PRK05097   81 HFNAEHQHTRKKSIDLEYRVWQRLAGLAQRRGKTLSETIVQLIEDAERKEKYANQMSSLKQDLKALLGKE 150
 
Name Accession Description Interval E-value
PRK05097 PRK05097
macrodomain Ter protein MatP;
1-150 7.91e-92

macrodomain Ter protein MatP;


Pssm-ID: 235344 [Multi-domain]  Cd Length: 150  Bit Score: 262.97  E-value: 7.91e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   1 MKYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKR 80
Cdd:PRK05097    1 MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDELLKLENEPVKVLEWIDKHMNPELVNRMKQTIRARRKR 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275  81 HFNAEQVHTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTSLKEDLSKLLSDD 150
Cdd:PRK05097   81 HFNAEHQHTRKKSIDLEYRVWQRLAGLAQRRGKTLSETIVQLIEDAERKEKYANQMSSLKQDLKALLGKE 150
MatP COG3120
Macrodomain Ter protein organizer, MatP/YcbG family [Replication, recombination and repair];
1-147 3.08e-87

Macrodomain Ter protein organizer, MatP/YcbG family [Replication, recombination and repair];


Pssm-ID: 442354  Cd Length: 149  Bit Score: 251.07  E-value: 3.08e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   1 MKYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKR 80
Cdd:COG3120     1 MKYQQLENLEAGWKWKYLVKKHREGENITRYIEQSAAQEAVQQLLTLENEPVKVLEWIKEHMNPALDNRLKQTIRARRKR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1326291275  81 HFNAEQVHTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTSLKEDLSKLL 147
Cdd:COG3120    81 HFNAEKQHTRKKSIDLEYLVWQRLSALAQRRGMTLSETIVQLIEEAERKEKYASQMSSLKQDLKALL 147
MatP pfam06303
MatP N-terminal domain; This family, many of whose members are YcbG, organizes the macrodomain ...
 2-85 7.21e-52

MatP N-terminal domain; This family, many of whose members are YcbG, organizes the macrodomain Ter of the chromosome of bacteria such as E coli. In these bacteria, insulated macrodomains influence the segregation of sister chromatids and the mobility of chromosomal DNA. organization of the Terminus region (Ter) into a macrodomain relies on the presence of a 13 bp motif called matS repeated 23 times in the 800-kb-long domain. MatS sites are the main targets in the E. coli chromosome of YcbG or MatP (macrodomain Ter protein). MatP accumulates in the cell as a discrete focus that co-localizes with the Ter macrodomain. The effects of MatP inactivation reveal its role as the main organizer of the Ter macrodomain: in the absence of MatP, DNA is less compacted, the mobility of markers is increased, and segregation of the Ter macrodomain occurs early in the cell cycle. A specific organizational system is required in the Terminus region for bacterial chromosome management during the cell cycle. This entry represents the N-terminal domain of MatP.


Pssm-ID: 428878  Cd Length: 84  Bit Score: 159.55  E-value: 7.21e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   2 KYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKRH 81
Cdd:pfam06303   1 KYQQLENLEAGWKWKYLVKKHREGEAITRYIEKSEAEAAVQQLLKLENEPVKVEEWIKAHMNPELENKLKQAIRARRKRH 80


                  ....
gi 1326291275  82 FNAE 85
Cdd:pfam06303  81 FNAE 84
 
Name Accession Description Interval E-value
PRK05097 PRK05097
macrodomain Ter protein MatP;
1-150 7.91e-92

macrodomain Ter protein MatP;


Pssm-ID: 235344 [Multi-domain]  Cd Length: 150  Bit Score: 262.97  E-value: 7.91e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   1 MKYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKR 80
Cdd:PRK05097    1 MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDELLKLENEPVKVLEWIDKHMNPELVNRMKQTIRARRKR 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275  81 HFNAEQVHTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTSLKEDLSKLLSDD 150
Cdd:PRK05097   81 HFNAEHQHTRKKSIDLEYRVWQRLAGLAQRRGKTLSETIVQLIEDAERKEKYANQMSSLKQDLKALLGKE 150
MatP COG3120
Macrodomain Ter protein organizer, MatP/YcbG family [Replication, recombination and repair];
1-147 3.08e-87

Macrodomain Ter protein organizer, MatP/YcbG family [Replication, recombination and repair];


Pssm-ID: 442354  Cd Length: 149  Bit Score: 251.07  E-value: 3.08e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   1 MKYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKR 80
Cdd:COG3120     1 MKYQQLENLEAGWKWKYLVKKHREGENITRYIEQSAAQEAVQQLLTLENEPVKVLEWIKEHMNPALDNRLKQTIRARRKR 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1326291275  81 HFNAEQVHTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTSLKEDLSKLL 147
Cdd:COG3120    81 HFNAEKQHTRKKSIDLEYLVWQRLSALAQRRGMTLSETIVQLIEEAERKEKYASQMSSLKQDLKALL 147
MatP pfam06303
MatP N-terminal domain; This family, many of whose members are YcbG, organizes the macrodomain ...
 2-85 7.21e-52

MatP N-terminal domain; This family, many of whose members are YcbG, organizes the macrodomain Ter of the chromosome of bacteria such as E coli. In these bacteria, insulated macrodomains influence the segregation of sister chromatids and the mobility of chromosomal DNA. organization of the Terminus region (Ter) into a macrodomain relies on the presence of a 13 bp motif called matS repeated 23 times in the 800-kb-long domain. MatS sites are the main targets in the E. coli chromosome of YcbG or MatP (macrodomain Ter protein). MatP accumulates in the cell as a discrete focus that co-localizes with the Ter macrodomain. The effects of MatP inactivation reveal its role as the main organizer of the Ter macrodomain: in the absence of MatP, DNA is less compacted, the mobility of markers is increased, and segregation of the Ter macrodomain occurs early in the cell cycle. A specific organizational system is required in the Terminus region for bacterial chromosome management during the cell cycle. This entry represents the N-terminal domain of MatP.


Pssm-ID: 428878  Cd Length: 84  Bit Score: 159.55  E-value: 7.21e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275   2 KYQQLENLECGWKWNYLVKKWKEGESITCHIDSSEADVAVQALLKLEHQPTGVLEWISNNMSPELDNKLKQAIRAKRKRH 81
Cdd:pfam06303   1 KYQQLENLEAGWKWKYLVKKHREGEAITRYIEKSEAEAAVQQLLKLENEPVKVEEWIKAHMNPELENKLKQAIRARRKRH 80


                  ....
gi 1326291275  82 FNAE 85
Cdd:pfam06303  81 FNAE 84
MatP_C pfam17414
MatP C-terminal ribbon-helix-helix domain; This family, many of whose members are YcbG, ...
 88-147 2.08e-26

MatP C-terminal ribbon-helix-helix domain; This family, many of whose members are YcbG, organizes the macrodomain Ter of the chromosome of bacteria such as E coli. In these bacteria, insulated macrodomains influence the segregation of sister chromatids and the mobility of chromosomal DNA. organization of the Terminus region (Ter) into a macrodomain relies on the presence of a 13 bp motif called matS repeated 23 times in the 800-kb-long domain. MatS sites are the main targets in the E. coli chromosome of YcbG or MatP (macrodomain Ter protein). MatP accumulates in the cell as a discrete focus that co-localizes with the Ter macrodomain. The effects of MatP inactivation reveal its role as the main organizer of the Ter macrodomain: in the absence of MatP, DNA is less compacted, the mobility of markers is increased, and segregation of the Ter macrodomain occurs early in the cell cycle. A specific organizational system is required in the Terminus region for bacterial chromosome management during the cell cycle. This entry represents the C-terminal ribbon-helix-helix domain.


Pssm-ID: 435905  Cd Length: 60  Bit Score: 94.04  E-value: 2.08e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1326291275  88 HTKKKSIDLDYRVWEKLSQRANELGCTLSDAIEYLVSEASRSEQASKTVTSLKEDLSKLL 147
Cdd:pfam17414   1 HTRKKSIDLDYRVWERLSKLSQRLGMTLSETIEYLIDEAERKEKYSEQMSSLKADLKDLL 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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