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Conserved domains on  [gi|13385848|ref|NP_080622|]
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Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Elongin_A super family cl06096
RNA polymerase II transcription factor SIII (Elongin) subunit A; This family represents a ...
265-302 4.28e-03

RNA polymerase II transcription factor SIII (Elongin) subunit A; This family represents a conserved region within RNA polymerase II transcription factor SIII (Elongin) subunit A. In mammals, the Elongin complex activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin is a heterotrimer composed of A, B, and C subunits of 110, 18, and 15 kilodaltons, respectively. Subunit A has been shown to function as the transcriptionally active component of Elongin.


The actual alignment was detected with superfamily member pfam06881:

Pssm-ID: 399694  Cd Length: 105  Bit Score: 36.42  E-value: 4.28e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 13385848   265 LWKRLCQYHFSERqiRKRLILSDKGQLDWKKMYFKLVR 302
Cdd:pfam06881  41 LWKRFIKRDFPEW--AEEKDYEPKNPKSWRKLYEKLKE 76
 
Name Accession Description Interval E-value
Elongin_A pfam06881
RNA polymerase II transcription factor SIII (Elongin) subunit A; This family represents a ...
265-302 4.28e-03

RNA polymerase II transcription factor SIII (Elongin) subunit A; This family represents a conserved region within RNA polymerase II transcription factor SIII (Elongin) subunit A. In mammals, the Elongin complex activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin is a heterotrimer composed of A, B, and C subunits of 110, 18, and 15 kilodaltons, respectively. Subunit A has been shown to function as the transcriptionally active component of Elongin.


Pssm-ID: 399694  Cd Length: 105  Bit Score: 36.42  E-value: 4.28e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 13385848   265 LWKRLCQYHFSERqiRKRLILSDKGQLDWKKMYFKLVR 302
Cdd:pfam06881  41 LWKRFIKRDFPEW--AEEKDYEPKNPKSWRKLYEKLKE 76
 
Name Accession Description Interval E-value
Elongin_A pfam06881
RNA polymerase II transcription factor SIII (Elongin) subunit A; This family represents a ...
265-302 4.28e-03

RNA polymerase II transcription factor SIII (Elongin) subunit A; This family represents a conserved region within RNA polymerase II transcription factor SIII (Elongin) subunit A. In mammals, the Elongin complex activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin is a heterotrimer composed of A, B, and C subunits of 110, 18, and 15 kilodaltons, respectively. Subunit A has been shown to function as the transcriptionally active component of Elongin.


Pssm-ID: 399694  Cd Length: 105  Bit Score: 36.42  E-value: 4.28e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 13385848   265 LWKRLCQYHFSERqiRKRLILSDKGQLDWKKMYFKLVR 302
Cdd:pfam06881  41 LWKRFIKRDFPEW--AEEKDYEPKNPKSWRKLYEKLKE 76
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.19
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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