NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1344169025|ref|NP_001347737|]
View 

G protein-activated inward rectifier potassium channel 3 [Mus musculus]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
IRK_C pfam17655
Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has ...
171-334 2.88e-98

Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has an Ig fold.


:

Pssm-ID: 465439  Cd Length: 174  Bit Score: 289.88  E-value: 2.88e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025 171 LVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHE 250
Cdd:pfam17655   1 LKFSKNAVICQRDGKLCLMFRVGDLRKSHLIEAHVRAQLLKTRVTKEGEVIPLYQVDLDLGVDTGSDRIFLVWPLTVYHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025 251 IDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLED-GFYEVDYASFHETFEVP 329
Cdd:pfam17655  81 IDEDSPLYDLSAKDLLEEDFELVVILEGTVESTGMTTQARTSYLPEEILWGHRFEPVISYSKeGRYVVDYSNFDKTVEVP 160

                  ....*
gi 1344169025 330 TPSCS 334
Cdd:pfam17655 161 TPHCS 165
IRK pfam01007
Inward rectifier potassium channel transmembrane domain;
25-164 3.61e-73

Inward rectifier potassium channel transmembrane domain;


:

Pssm-ID: 460023  Cd Length: 141  Bit Score: 224.75  E-value: 3.61e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025  25 VEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNN 103
Cdd:pfam01007   1 VSKNGHCNVVFTNIPEkSLRYLQDIFTTLVDLKWRYMLLLFSLSFVLSWLIFGLIWYLIAYSHGDLDQRPDDGHTPCVYN 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1344169025 104 LNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQP 164
Cdd:pfam01007  81 VHSFTSAFLFSIETQTTIGYGFRYVTEECPEAIFLLVFQSIVGCLIDAFMIGIVFAKMARP 141
 
Name Accession Description Interval E-value
IRK_C pfam17655
Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has ...
171-334 2.88e-98

Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has an Ig fold.


Pssm-ID: 465439  Cd Length: 174  Bit Score: 289.88  E-value: 2.88e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025 171 LVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHE 250
Cdd:pfam17655   1 LKFSKNAVICQRDGKLCLMFRVGDLRKSHLIEAHVRAQLLKTRVTKEGEVIPLYQVDLDLGVDTGSDRIFLVWPLTVYHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025 251 IDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLED-GFYEVDYASFHETFEVP 329
Cdd:pfam17655  81 IDEDSPLYDLSAKDLLEEDFELVVILEGTVESTGMTTQARTSYLPEEILWGHRFEPVISYSKeGRYVVDYSNFDKTVEVP 160

                  ....*
gi 1344169025 330 TPSCS 334
Cdd:pfam17655 161 TPHCS 165
IRK pfam01007
Inward rectifier potassium channel transmembrane domain;
25-164 3.61e-73

Inward rectifier potassium channel transmembrane domain;


Pssm-ID: 460023  Cd Length: 141  Bit Score: 224.75  E-value: 3.61e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025  25 VEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNN 103
Cdd:pfam01007   1 VSKNGHCNVVFTNIPEkSLRYLQDIFTTLVDLKWRYMLLLFSLSFVLSWLIFGLIWYLIAYSHGDLDQRPDDGHTPCVYN 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1344169025 104 LNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQP 164
Cdd:pfam01007  81 VHSFTSAFLFSIETQTTIGYGFRYVTEECPEAIFLLVFQSIVGCLIDAFMIGIVFAKMARP 141
 
Name Accession Description Interval E-value
IRK_C pfam17655
Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has ...
171-334 2.88e-98

Inward rectifier potassium channel C-terminal domain; This cytoplasmic C-terminal domain has an Ig fold.


Pssm-ID: 465439  Cd Length: 174  Bit Score: 289.88  E-value: 2.88e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025 171 LVFSSHAVVSLRDGRLCLMFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHE 250
Cdd:pfam17655   1 LKFSKNAVICQRDGKLCLMFRVGDLRKSHLIEAHVRAQLLKTRVTKEGEVIPLYQVDLDLGVDTGSDRIFLVWPLTVYHV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025 251 IDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLED-GFYEVDYASFHETFEVP 329
Cdd:pfam17655  81 IDEDSPLYDLSAKDLLEEDFELVVILEGTVESTGMTTQARTSYLPEEILWGHRFEPVISYSKeGRYVVDYSNFDKTVEVP 160

                  ....*
gi 1344169025 330 TPSCS 334
Cdd:pfam17655 161 TPHCS 165
IRK pfam01007
Inward rectifier potassium channel transmembrane domain;
25-164 3.61e-73

Inward rectifier potassium channel transmembrane domain;


Pssm-ID: 460023  Cd Length: 141  Bit Score: 224.75  E-value: 3.61e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1344169025  25 VEKDGRCNVQQGNVRE-TYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNN 103
Cdd:pfam01007   1 VSKNGHCNVVFTNIPEkSLRYLQDIFTTLVDLKWRYMLLLFSLSFVLSWLIFGLIWYLIAYSHGDLDQRPDDGHTPCVYN 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1344169025 104 LNGFVAAFLFSIETETTIGYGHRVITDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQP 164
Cdd:pfam01007  81 VHSFTSAFLFSIETQTTIGYGFRYVTEECPEAIFLLVFQSIVGCLIDAFMIGIVFAKMARP 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH