NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1370622178|gb|PSN32330|]
View 

hypothetical protein C0J52_17636 [Blattella germanica]

Protein Classification

galectin family protein( domain architecture ID 10658251)

galectin family protein may exclusively bind beta-galactosides such as lactose in a manner independent of metal ions

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 19-143 1.47e-55

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


:

Pssm-ID: 214904  Cd Length: 122  Bit Score: 177.40  E-value: 1.47e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178   19 GGFHPGKMVRIQGTVHPSANRFAINLQCGPNmlprDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIARGQGFEI 98
Cdd:smart00908   2 GGLSPGSSITIRGIVLPDAKRFSINLQCGPN----ADIALHFNPRFDEGTIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1370622178   99 IILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTISLIQ 143
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRLPLESIDTLEISGDVQLTSVQ 122
 
Name Accession Description Interval E-value
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 19-143 1.47e-55

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


Pssm-ID: 214904  Cd Length: 122  Bit Score: 177.40  E-value: 1.47e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178   19 GGFHPGKMVRIQGTVHPSANRFAINLQCGPNmlprDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIARGQGFEI 98
Cdd:smart00908   2 GGLSPGSSITIRGIVLPDAKRFSINLQCGPN----ADIALHFNPRFDEGTIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1370622178   99 IILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTISLIQ 143
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRLPLESIDTLEISGDVQLTSVQ 122
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 12-143 2.78e-53

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


Pssm-ID: 238025  Cd Length: 127  Bit Score: 171.66  E-value: 2.78e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178  12 PYVGLIDGGFHPGKMVRIQGTVHPSANRFAINLQCGPnmlprDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIA 91
Cdd:cd00070     1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGS-----SDIALHFNPRFDENVIVRNSFLNGNWGPEERSGGFPFQ 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370622178  92 RGQGFEIIILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTISLIQ 143
Cdd:cd00070    76 PGQPFELTILVEEDKFQIFVNGQHFFSFPHRLPLESIDYLSINGDVSLTSVE 127
Gal-bind_lectin pfam00337
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ...
 19-140 5.28e-51

Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).


Pssm-ID: 459768  Cd Length: 124  Bit Score: 165.89  E-value: 5.28e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178  19 GGFHPGKMVRIQGTVHPSANRFAINLQCGPNmlPRDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIARGQGFEI 98
Cdd:pfam00337   2 GGLQPGSSLTIKGIVLPDAQRFSINLQTGVG--PSDDIALHFNPRFDENVIVRNSRQNGQWGQEEREGGFPFQPGQPFEL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1370622178  99 IILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTIS 140
Cdd:pfam00337  80 TILVGDDHFKIYVNGQHFTTFKHRLPPEDIDALQVRGDVKLT 121
 
Name Accession Description Interval E-value
Gal-bind_lectin smart00908
Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are ...
 19-143 1.47e-55

Galactoside-binding lectin; Animal lectins display a wide variety of architectures. They are classified according to the carbohydrate-recognition domain (CRD) of which there are two main types, S-type and C-type. Galectins (previously S-lectins) bind exclusively beta-galactosides like lactose. They do not require metal ions for activity. Galectins are found predominantly, but not exclusively in mammals. Their function is unclear. They are developmentally regulated and may be involved in differentiation, cellular regulation and tissue construction.


Pssm-ID: 214904  Cd Length: 122  Bit Score: 177.40  E-value: 1.47e-55
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178   19 GGFHPGKMVRIQGTVHPSANRFAINLQCGPNmlprDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIARGQGFEI 98
Cdd:smart00908   2 GGLSPGSSITIRGIVLPDAKRFSINLQCGPN----ADIALHFNPRFDEGTIVRNSKQNGKWGKEERSGGFPFQPGQPFEL 77

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*
gi 1370622178   99 IILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTISLIQ 143
Cdd:smart00908  78 EILVEEDEFKVAVNGQHFLEFPHRLPLESIDTLEISGDVQLTSVQ 122
GLECT cd00070
Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as ...
 12-143 2.78e-53

Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may be involved in differentiation, cell-cell interaction and cellular regulation.


Pssm-ID: 238025  Cd Length: 127  Bit Score: 171.66  E-value: 2.78e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178  12 PYVGLIDGGFHPGKMVRIQGTVHPSANRFAINLQCGPnmlprDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIA 91
Cdd:cd00070     1 PYKLPLPGGLKPGSTLTVKGRVLPNAKRFSINLGTGS-----SDIALHFNPRFDENVIVRNSFLNGNWGPEERSGGFPFQ 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1370622178  92 RGQGFEIIILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTISLIQ 143
Cdd:cd00070    76 PGQPFELTILVEEDKFQIFVNGQHFFSFPHRLPLESIDYLSINGDVSLTSVE 127
Gal-bind_lectin pfam00337
Galactoside-binding lectin; This family contains galactoside binding lectins. The family also ...
 19-140 5.28e-51

Galactoside-binding lectin; This family contains galactoside binding lectins. The family also includes enzymes such as human eosinophil lysophospholipase (EC:3.1.1.5).


Pssm-ID: 459768  Cd Length: 124  Bit Score: 165.89  E-value: 5.28e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178  19 GGFHPGKMVRIQGTVHPSANRFAINLQCGPNmlPRDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIARGQGFEI 98
Cdd:pfam00337   2 GGLQPGSSLTIKGIVLPDAQRFSINLQTGVG--PSDDIALHFNPRFDENVIVRNSRQNGQWGQEEREGGFPFQPGQPFEL 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1370622178  99 IILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTIS 140
Cdd:pfam00337  80 TILVGDDHFKIYVNGQHFTTFKHRLPPEDIDALQVRGDVKLT 121
GLECT smart00276
Galectin; Galectin - galactose-binding lectin
 13-145 1.33e-45

Galectin; Galectin - galactose-binding lectin


Pssm-ID: 214596  Cd Length: 128  Bit Score: 152.00  E-value: 1.33e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370622178   13 YVGLIDGGFHPGKMVRIQGTVHPSANRFAINLQCGPnmlprDDIAVHVCPKFHENHITRNSLQNMSWGVEENHGHMPIAR 92
Cdd:smart00276   1 FTLPIPGGLKPGQTLTVRGIVLPDAKRFSINLLTGG-----DDIALHFNPRFNENKIVCNSKLNGSWGSEEREGGFPFQP 75

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1370622178   93 GQGFEIIILCDPSHYKIAVNGNHYAEFGHRIPFQRVSYLTIDGDVTISLIQYE 145
Cdd:smart00276  76 GQPFDLTIIVQPDHFQIFVNGVHITTFPHRLPLESIDYLSINGDVQLTSVSFE 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH